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Cheap flights from St. Louis to Spain from $280

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from St. Louis to Spain departing on 10/25. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Cheap round-trip flights

United Airlines Logo
5:28 pm - 6:40 amSTL-MAD
30h 12m2 stops
United Airlines Logo
10:50 am - 11:57 pmMAD-STL
20h 07m1 stop
$413United Airlines
Find Deal
lun., oct. 6 - mié., oct. 22
Air Canada Logo
1:30 pm - 6:40 amSTL-MAD
10h 10m1 stop
Air Canada Logo
12:30 pm - 3:18 pmMAD-STL
33h 48m1 stop
$414Air Canada
Find Deal
lun., oct. 6 - mié., oct. 22
American Airlines Logo
10:34 am - 6:25 amSTL-MAD
12h 51m1 stop
American Airlines Logo
11:50 am - 9:29 pmMAD-STL
16h 39m1 stop
$435American Airlines
Find Deal
dom., sep. 21 - mar., oct. 7
Iberia Logo
2:51 pm - 10:20 amSTL-MAD
12h 29m1 stop
Iberia Logo
11:35 am - 8:23 pmMAD-STL
15h 48m1 stop
$461Iberia
Find Deal
mié., nov. 5 - mié., nov. 12
British Airways Logo
1:20 pm - 9:25 amSTL-MAD
13h 05m1 stop
British Airways Logo
7:25 pm - 4:50 pmMAD-STL
28h 25m2 stops
$465British Airways
Find Deal
mié., dic. 3 - lun., dic. 8
Lufthansa Logo
6:43 pm - 5:50 pmSTL-MAD
16h 07m2 stops
Lufthansa Logo
12:00 pm - 11:42 pmMAD-STL
18h 42m2 stops
$483Lufthansa
Find Deal
dom., nov. 23 - mar., dic. 2
Iberia Logo
4:45 pm - 8:55 amSTL-MAD
10h 10m1 stop
Iberia Logo
1:15 pm - 8:55 pmMAD-STL
14h 40m1 stop
$488Iberia
Find Deal
mar., oct. 28 - dom., nov. 23
Lufthansa Logo
3:30 pm - 6:25 pmSTL-BIO
19h 55m1 stop
Lufthansa Logo
6:45 am - 11:57 pmBIO-STL
24h 12m2 stops
$550Lufthansa
Find Deal
dom., oct. 5 - mié., oct. 15
British Airways Logo
1:03 pm - 9:05 amSTL-BCN
13h 02m1 stop
British Airways Logo
2:00 pm - 8:20 pmBCN-STL
13h 20m1 stop
$581British Airways
Find Deal
mié., oct. 1 - vie., oct. 10
American Airlines Logo
7:30 am - 8:50 amSTL-GRX
18h 20m2 stops
American Airlines Logo
9:40 pm - 9:56 amGRX-STL
19h 16m2 stops
$733American Airlines
Find Deal
sáb., feb. 21 - vie., feb. 27

Iberia flights from St. Louis to Spain

Our best Iberia deals on St. Louis to Spain flight tickets
Iberia
Nov 5
STL2:51 pmLambert-St Louis
12h 29m
1 stop
MAD10:20 amMadrid Barajas
Nov 12
MAD11:35 amMadrid Barajas
15h 48m
1 stop
STL8:23 pmLambert-St Louis
$461
Find similar
Iberia
Oct 28
STL4:45 pmLambert-St Louis
10h 10m
1 stop
MAD8:55 amMadrid Barajas
Nov 23
MAD1:15 pmMadrid Barajas
14h 40m
1 stop
STL8:55 pmLambert-St Louis
$488
Find similar
Iberia
Oct 24
STL8:05 pmLambert-St Louis
10h 20m
1 stop
MAD1:25 pmMadrid Barajas
Nov 7
MAD1:15 pmMadrid Barajas
14h 40m
1 stop
STL8:55 pmLambert-St Louis
$494
Find similar

United Airlines flights from St. Louis to Spain

Our best United Airlines deals on St. Louis to Spain flight tickets
United Airlines
Oct 6
STL5:28 pmLambert-St Louis
30h 12m
2 stops
MAD6:40 amMadrid Barajas
Oct 22
MAD10:50 amMadrid Barajas
20h 07m
1 stop
STL11:57 pmLambert-St Louis
$413
Find similar
United Airlines
Oct 7
STL1:30 pmLambert-St Louis
10h 10m
1 stop
MAD6:40 amMadrid Barajas
Oct 15
MAD12:45 pmMadrid Barajas
33h 59m
2 stops
STL3:44 pmLambert-St Louis
$418
Find similar
United Airlines
Oct 12
STL12:25 pmLambert-St Louis
35h 15m
2 stops
MAD6:40 amMadrid Barajas
Oct 22
MAD12:45 pmMadrid Barajas
32h 42m
2 stops
STL2:27 pmLambert-St Louis
$422
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from St. Louis to Spain that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated septiembre 4, 2025.
Use the filters below to find and compare flights from St. Louis to Spain that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

St. LouisMadrid

STL - MAD

STLMAD

Lambert-St Louis

lun. 10/6

5:28 pm-6:40 am

2 stops30h 12m

Madrid Barajas

mié. 10/22

10:50 am-11:57 pm

1 stop20h 07m

$413

St. LouisMadrid

STL - MAD

STLMAD

Lambert-St Louis

lun. 10/6

1:30 pm-6:40 am

1 stop10h 10m

Madrid Barajas

mié. 10/22

12:30 pm-3:18 pm

1 stop33h 48m

$414

St. LouisMadrid

STL - MAD

STLMAD

Lambert-St Louis

dom. 9/21

10:34 am-6:25 am

1 stop12h 51m

Madrid Barajas

mar. 10/7

11:50 am-9:29 pm

1 stop16h 39m

$435

St. LouisMadrid

STL - MAD

STLMAD

Lambert-St Louis

mié. 11/5

2:51 pm-10:20 am

1 stop12h 29m

Madrid Barajas

mié. 11/12

11:35 am-8:23 pm

1 stop15h 48m

$461

St. LouisMadrid

STL - MAD

STLMAD

Lambert-St Louis

mié. 12/3

1:20 pm-9:25 am

1 stop13h 05m

Madrid Barajas

lun. 12/8

7:25 pm-4:50 pm

2 stops28h 25m

$465

St. LouisMadrid

STL - MAD

STLMAD

Lambert-St Louis

dom. 11/23

6:43 pm-5:50 pm

2 stops16h 07m

Madrid Barajas

mar. 12/2

12:00 pm-11:42 pm

2 stops18h 42m

$483

St. LouisMadrid

STL - MAD

STLMAD

Lambert-St Louis

mar. 10/28

4:45 pm-8:55 am

1 stop10h 10m

Madrid Barajas

dom. 11/23

1:15 pm-8:55 pm

1 stop14h 40m

$488

St. LouisBilbao

STL - BIO

STLBIO

Lambert-St Louis

dom. 10/5

3:30 pm-6:25 pm

1 stop19h 55m

Bilbao

mié. 10/15

6:45 am-11:57 pm

2 stops24h 12m

$550

St. LouisBarcelona

STL - BCN

STLBCN

Lambert-St Louis

mié. 10/1

1:03 pm-9:05 am

1 stop13h 02m

Barcelona-El Prat

vie. 10/10

2:00 pm-8:20 pm

1 stop13h 20m

$581

St. LouisGranada

STL - GRX

STLGRX

Lambert-St Louis

sáb. 2/21

7:30 am-8:50 am

2 stops18h 20m

Granada Federico Garcia Lorca

vie. 2/27

9:40 pm-9:56 am

2 stops19h 16m

$733

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Spain from

How to get the cheapest flight ticket from St. Louis to Spain

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Spain?

If you don’t want to visit Spain in February, then you should wait until November to fly from St. Louis, when ticket prices are also cheap, with an average price of $755.

What is the cheapest day to depart on your flight to Spain?

The cheapest day to depart from St. Louis to Spain is on a Tuesday when prices can be found for as low as $867. When flying out on a Thursday, the most expensive travel day of the week, you can expect to see flight prices from St. Louis to Spain for around $1,135.

What is the cheapest time of day to depart on your flight to Spain?

Flying to Spain from St. Louis in the morning is the least expensive time of day to depart. momondo users have found prices as low as $905 when looking at flights departing in the morning. In contrast, the most expensive time of day to depart to Spain is in the afternoon when prices are around $1,043.

How far in advance should I book a flight to Spain?

You are more likely to see cheaper flights to Spain from St. Louis when booking weeks ahead of your departure date. In general, you can expect to find flights to Spain for around $960 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Spain from St. Louis for as low as $736 on momondo.

Can stopping save me money on St. Louis to Spain flights?

You could potentially save up to 11% on your flight if you consider stops on a St. Louis to Spain flight.

Cheap St. Louis to Spain flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from St. Louis to Spain

Direct flights

None
There are no direct flights from St. Louis to Spain. There are no popular flight routes from St. Louis to Spain.
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  • When did momondo last update prices for flights from Lambert-St Louis Airport to Spain?

    Prices for flights from Lambert-St Louis Airport to Spain were last updated today.

  • How many operators does momondo search for flights from Lambert-St Louis Airport to Spain?

  • How old do you have to be to fly from Lambert-St Louis Airport to Spain?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Lambert-St Louis Airport to Spain.

  • What documentation or ID do you need to fly to Spain?

    The travel and health documents required for your trip to Spain can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Spain. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Best airlines flying from St. Louis to Spain

Compare and see reviews for airlines that fly from St. Louis to Spain with momondo
Airline
Rating
Free Cancellation
Price
British AirwaysPriceFrom $546Free CancellationRating
6.7
7,345 reviews
Search British Airways flights
United AirlinesPriceFrom $573Free CancellationRating
7.4
8,939 reviews
Search United Airlines flights
IberiaPriceFrom $586Free CancellationRating
7.0
2,913 reviews
Search Iberia flights
KLMPriceFrom $590Free CancellationRating
7.8
1,383 reviews
Search KLM flights
DeltaPriceFrom $602Free CancellationRating
7.9
7,977 reviews
Search Delta flights
LufthansaPriceFrom $605Free CancellationRating
6.8
7,390 reviews
Search Lufthansa flights
American AirlinesPriceFrom $616Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights
Air CanadaPriceFrom $629Free CancellationRating
7.1
10,000 reviews
Search Air Canada flights

Why use momondo?

Why should I use momondo to find a flight deal from St. Louis to Spain?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from St. Louis to Spain. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from St. Louis to Spain with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Spain from St. Louis with this policy.

How can momondo help me find flights from St. Louis to Spain?

Once you have performed a search for St. Louis to Spain flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from St. Louis to Spain right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Spain from St. Louis. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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