Which layover airport offers the lowest fares from St. Louis to Prague?

Flights via London (LHR) offer the lowest average round-trip price of $714.

Which airport is the most popular layover for flights between St. Louis and Prague?

London (LHR) was the most common stop: 56% of momondo users choosing 1-stop flights on this route connected there.

What airlines fly to Prague?

United Airlines, Lufthansa and Delta are the top three most popular airlines that fly to Prague from St. Louis according to our data. United Airlines is the first choice among our users, with 39% of people opting to fly with this airline when traveling to Prague. Keep in mind that there are 5 different airlines that fly to Prague on a routine basis, so you have a few additional options to choose from.

Which layover airport has the shortest connection time from St. Louis to Prague?

Frankfurt am Main (FRA) has the shortest average layover time for this route: 2h 41m.

Which layover airport has the shortest travel time from St. Louis to Prague?

Flights connecting via Frankfurt am Main (FRA) have the shortest average one-way travel time: 11h 48m.

What is the cheapest airline that flies from Lambert-St Louis to Václav Havel Prague?

United Airlines, British Airways, and Lufthansa are the most popular carriers operating from Lambert-St Louis to Václav Havel Prague

When did momondo last update prices for flights from Lambert-St Louis Airport to Václav Havel Prague Airport?

Prices for flights from Lambert-St Louis Airport to Václav Havel Prague Airport are refreshed on a daily basis.

How many operators does momondo search for flights from Lambert-St Louis Airport to Václav Havel Prague Airport?

The number of operators available for flights from Lambert-St Louis Airport to Václav Havel Prague Airport is 5 as of December 2025.

How old do you have to be to fly from Lambert-St Louis Airport to Václav Havel Prague Airport?

The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Lambert-St Louis Airport to Václav Havel Prague Airport.

What documentation or ID do you need to fly to Václav Havel Prague Airport?

The travel and health documents you'll need for your trip to Václav Havel Prague Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Václav Havel Prague Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

$408 Cheap Flights from St. Louis to Prague in 2025/26

Q: What is the typical price of a round-trip flight between St. Louis and Prague?

Prices are currently low for flights on this route. Typical prices usually range from $739 to $1,097. The lowest price recently found on this route was $492.

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Cheap round-trip flights

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11:14 am - 5:00 pm

STL

PRG

22h 46m2 stops

8:55 pm - 7:30 pm

PRG

STL

29h 35m1 stop

$492British Airways

Mon, Apr 20 - Mon, Apr 27

6:40 pm - 4:05 pm

STL

PRG

14h 25m2 stops

7:25 am - 10:58 pm

PRG

STL

22h 33m2 stops

$494Lufthansa

Sun, Jan 25 - Sun, Feb 1

5:04 pm - 9:05 pm

STL

PRG

21h 01m2 stops

1:55 pm - 9:15 pm

PRG

STL

38h 20m2 stops

$495British Airways

Fri, Jan 16 - Sun, Jan 25

10:00 pm - 9:15 am

STL

PRG

28h 15m1 stop

10:20 am - 7:30 pm

PRG

STL

16h 10m1 stop

$496British Airways

Tue, Apr 21 - Tue, Apr 28

9:57 am - 1:05 pm

STL

PRG

20h 08m2 stops

7:25 am - 3:29 pm

PRG

STL

39h 04m2 stops

$505United Airlines

Fri, Feb 6 - Tue, Feb 10

3:50 pm - 9:50 am

STL

PRG

11h 00m1 stop

10:30 am - 10:58 pm

PRG

STL

19h 28m2 stops

$507Lufthansa

Fri, Jan 16 - Sun, Jan 25

4:05 pm - 1:55 pm

STL

PRG

14h 50m2 stops

10:30 am - 10:58 pm

PRG

STL

19h 28m2 stops

$508Multiple Airlines

Fri, Jan 16 - Sun, Jan 25

6:35 pm - 9:20 pm

STL

PRG

43h 45m2 stops

6:10 am - 1:25 pm

PRG

STL

14h 15m1 stop

$510Lufthansa

Mon, Apr 20 - Wed, Apr 29

3:50 pm - 2:05 pm

STL

PRG

15h 15m1 stop

7:35 am - 3:29 pm

PRG

STL

38h 54m2 stops

$513United Airlines

Fri, Jan 30 - Fri, Feb 6

9:57 am - 2:05 pm

STL

PRG

21h 08m2 stops

7:25 am - 10:58 pm

PRG

STL

22h 33m2 stops

$521United Airlines

Fri, Feb 6 - Tue, Feb 10

Lufthansa flights from St. Louis to Prague

Our best Lufthansa deals on St. Louis to Prague flight tickets

Lufthansa

Jan 25

STL6:40 pmLambert-St Louis

14h 25m

2 stops

PRG4:05 pmVáclav Havel Prague

Feb 1

PRG7:25 amVáclav Havel Prague

22h 33m

2 stops

STL10:58 pmLambert-St Louis

$494

Find similar

Lufthansa

Jan 16

STL3:50 pmLambert-St Louis

11h 00m

1 stop

PRG9:50 amVáclav Havel Prague

Jan 25

PRG10:30 amVáclav Havel Prague

19h 28m

2 stops

STL10:58 pmLambert-St Louis

$507

Find similar

Lufthansa

Apr 20

STL6:35 pmLambert-St Louis

43h 45m

2 stops

PRG9:20 pmVáclav Havel Prague

Apr 29

PRG6:10 amVáclav Havel Prague

14h 15m

1 stop

STL1:25 pmLambert-St Louis

$510

Find similar

United Airlines flights from St. Louis to Prague

Our best United Airlines deals on St. Louis to Prague flight tickets

United Airlines

Feb 6

STL9:57 amLambert-St Louis

20h 08m

2 stops

PRG1:05 pmVáclav Havel Prague

Feb 10

PRG7:25 amVáclav Havel Prague

39h 04m

2 stops

STL3:29 pmLambert-St Louis

$505

Find similar

United Airlines

Jan 30

STL3:50 pmLambert-St Louis

15h 15m

1 stop

PRG2:05 pmVáclav Havel Prague

Feb 3

PRG7:25 amVáclav Havel Prague

38h 50m

2 stops

STL3:15 pmLambert-St Louis

$513

Find similar

United Airlines

Feb 6

STL9:57 amLambert-St Louis

21h 08m

2 stops

PRG2:05 pmVáclav Havel Prague

Feb 10

PRG7:25 amVáclav Havel Prague

22h 33m

2 stops

STL10:58 pmLambert-St Louis

$521

Find similar

Fly from

Fly to

Route

Depart

Return

Price

St. LouisPrague

STL - PRG

STLPRG

Lambert-St Louis

Mon 4/20

11:14 am-5:00 pm

2 stops22h 46m

Václav Havel Prague

Mon 4/27

8:55 pm-7:30 pm

1 stop29h 35m

$492

St. LouisPrague

STL - PRG

STLPRG

Lambert-St Louis

Sun 1/25

6:40 pm-4:05 pm

2 stops14h 25m

Václav Havel Prague

Sun 2/1

7:25 am-10:58 pm

2 stops22h 33m

$494

St. LouisPrague

STL - PRG

STLPRG

Lambert-St Louis

Fri 1/16

5:04 pm-9:05 pm

2 stops21h 01m

Václav Havel Prague

Sun 1/25

1:55 pm-9:15 pm

2 stops38h 20m

$495

St. LouisPrague

STL - PRG

STLPRG

Lambert-St Louis

Tue 4/21

10:00 pm-9:15 am

1 stop28h 15m

Václav Havel Prague

Tue 4/28

10:20 am-7:30 pm

1 stop16h 10m

$496

St. LouisPrague

STL - PRG

STLPRG

Lambert-St Louis

Fri 2/6

9:57 am-1:05 pm

2 stops20h 08m

Václav Havel Prague

Tue 2/10

7:25 am-3:29 pm

2 stops39h 04m

$505

St. LouisPrague

STL - PRG

STLPRG

Lambert-St Louis

Fri 1/16

3:50 pm-9:50 am

1 stop11h 00m

Václav Havel Prague

Sun 1/25

10:30 am-10:58 pm

2 stops19h 28m

$507

St. LouisPrague

STL - PRG

STLPRG

Lambert-St Louis

Fri 1/16

4:05 pm-1:55 pm

2 stops14h 50m

Václav Havel Prague

Sun 1/25

10:30 am-10:58 pm

2 stops19h 28m

$508

St. LouisPrague

STL - PRG

STLPRG

Lambert-St Louis

Mon 4/20

6:35 pm-9:20 pm

2 stops43h 45m

Václav Havel Prague

Wed 4/29

6:10 am-1:25 pm

1 stop14h 15m

$510

St. LouisPrague

STL - PRG

STLPRG

Lambert-St Louis

Fri 1/30

3:50 pm-2:05 pm

1 stop15h 15m

Václav Havel Prague

Fri 2/6

7:35 am-3:29 pm

2 stops38h 54m

$513

St. LouisPrague

STL - PRG

STLPRG

Lambert-St Louis

Fri 2/6

9:57 am-2:05 pm

2 stops21h 08m

Václav Havel Prague

Tue 2/10

7:25 am-10:58 pm

2 stops22h 33m

$521

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 19 resultsSorted by cheapest first

How to get the cheapest flight ticket from St. Louis to Prague

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Layovers

What is the typical price of a round-trip flight between St. Louis and Prague?

What is the cheapest month to fly to Prague?

In general, March is the cheapest month to fly from St. Louis to Prague. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $655. If you are unable to visit Prague during the month of March, then departing from St. Louis during the month January is also very affordable. Most momondo users find prices during this month for around $683.

What is the cheapest day to depart on your flight to Prague?

The cheapest day to depart from St. Louis to Prague is on a Thursday. Travelers who choose to depart for Prague on a Thursday will often find tickets for as low as $983. When flying out on a Sunday, the most expensive travel day of the week, you can expect to see flight prices from St. Louis to Prague for around $1,216.

What is the cheapest time of day to depart on your flight to Prague?

According to our data, the cheapest time of day to fly to Prague is in the morning. momondo users have found flights departing from St. Louis to Prague in the morning for as low as $1,013. Keep in mind that these prices may fluctuate based on what airline you choose and the time of year you plan to travel. Try not to purchase tickets at noon because they tend to be around $1,216. Of course, these prices can vary depending on the time of year and what airport you fly to.

Can stopping save me money on St. Louis to Prague flights?

You could potentially save up to 21% on your flight if you consider stops on a St. Louis to Prague flight.

When to book flights from St. Louis to Prague

Are you open to changing your travel dates? Check out the ideal times to fly from St. Louis to Prague according to our flight data. Find out which month and days have the cheapest flights.

Estimated round-trip price

Cheap St. Louis to Prague (STL to PRG) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from St. Louis to Prague

Fastest flight time	12h 30m
Direct flights	None

The fastest flight from St. Louis to Prague takes 12h 30m

There are no direct flights from St. Louis to Prague. There are no popular flight routes from St. Louis to Prague.

Search flight deals

How far is Lambert-St Louis to Václav Havel Prague by plane?
Lambert-St Louis and Václav Havel Prague are 4789.6 mi apart from one another. Flights usually cover this in 12h 30m, depending on flying conditions and air traffic around both airports.
When did momondo last update prices for flights from Lambert-St Louis Airport to Václav Havel Prague Airport?
Prices for flights from Lambert-St Louis Airport to Václav Havel Prague Airport are refreshed on a daily basis.
How many operators does momondo search for flights from Lambert-St Louis Airport to Václav Havel Prague Airport?
The number of operators available for flights from Lambert-St Louis Airport to Václav Havel Prague Airport is 5 as of December 2025.
How old do you have to be to fly from Lambert-St Louis Airport to Václav Havel Prague Airport?
The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Lambert-St Louis Airport to Václav Havel Prague Airport.
What documentation or ID do you need to fly to Václav Havel Prague Airport?
The travel and health documents you'll need for your trip to Václav Havel Prague Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Václav Havel Prague Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.
What is the most popular airline from St. Louis to Prague?
momondo data reveals that the most frequently booked airline on the route from St. Louis to Prague is United Airlines, representing 35% of all bookings. The subsequent popular airlines are Lufthansa at 28%, Delta at 15%, and Air Canada at 11%.

Best airlines flying from St. Louis to Prague

Compare and see reviews for airlines that fly from St. Louis to Prague with momondo

Airline	Rating	Free Cancellation	Price
United Airlines	PriceFrom $504	Free Cancellation	Rating 7.4 9,093 reviews	Search United Airlines flights
British Airways	PriceFrom $582	Free Cancellation	Rating 6.7 7,585 reviews	Search British Airways flights
Delta	PriceFrom $642	Free Cancellation	Rating 7.9 8,009 reviews	Search Delta flights
Lufthansa	PriceFrom $684	Free Cancellation	Rating 6.8 7,635 reviews	Search Lufthansa flights
Air Canada	PriceFrom $745	Free Cancellation	Rating 7.1 10,534 reviews	Search Air Canada flights

Český Krumlov

Pilsen

Liberec

Why use momondo?

Why should I use momondo to find a flight deal from St. Louis to Prague?

It is quick and easy to find St. Louis to Prague flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Prague that suits you.

Can I find flights from St. Louis to Prague with flexible booking policies on momondo?

Yes. All flights to Prague from St. Louis on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from St. Louis to Prague?

Once you have performed a search for St. Louis to Prague flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from St. Louis to Prague right now. Can momondo alert me if prices change?

If you are not ready to book a flight from St. Louis to Prague now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Prague and let you know when they change.

An easier way to manage your Prague trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

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Cheap flights from St. Louis to Prague from $408

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from St. Louis to Prague departing on 1/16. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.

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Filter for what you want

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Find the cheapest flights from St. Louis to Prague

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Cheap one-way flights

Lufthansa flights from St. Louis to Prague

Our best Lufthansa deals on St. Louis to Prague flight tickets

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Our best United Airlines deals on St. Louis to Prague flight tickets

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Use the filters below to find and compare flights from St. Louis to Prague that are best for you.

See travel insights to Prague from

How to get the cheapest flight ticket from St. Louis to Prague

What is the typical price of a round-trip flight between St. Louis and Prague?

What is the cheapest month to fly to Prague?

What is the cheapest day to depart on your flight to Prague?

What is the cheapest time of day to depart on your flight to Prague?

Can stopping save me money on St. Louis to Prague flights?

You could potentially save up to 21% on your flight if you consider stops on a St. Louis to Prague flight.

What is the cheapest airline that flies from Lambert-St Louis to Václav Havel Prague?

United Airlines, British Airways, and Lufthansa are the most popular carriers operating from Lambert-St Louis to Václav Havel Prague

What airlines fly to Prague?

Which airport is the most popular layover for flights between St. Louis and Prague?

London (LHR) was the most common stop: 56% of momondo users choosing 1-stop flights on this route connected there.

Which layover airport offers the lowest fares from St. Louis to Prague?

Flights via London (LHR) offer the lowest average round-trip price of $714.

Which layover airport has the shortest travel time from St. Louis to Prague?

Flights connecting via Frankfurt am Main (FRA) have the shortest average one-way travel time: 11h 48m.

Which layover airport has the shortest connection time from St. Louis to Prague?

Frankfurt am Main (FRA) has the shortest average layover time for this route: 2h 41m.

When to book flights from St. Louis to Prague

Cheap St. Louis to Prague (STL to PRG) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from St. Louis to Prague

Fastest flight time

Direct flights

How far is Lambert-St Louis to Václav Havel Prague by plane?

When did momondo last update prices for flights from Lambert-St Louis Airport to Václav Havel Prague Airport?

How many operators does momondo search for flights from Lambert-St Louis Airport to Václav Havel Prague Airport?

How old do you have to be to fly from Lambert-St Louis Airport to Václav Havel Prague Airport?

What documentation or ID do you need to fly to Václav Havel Prague Airport?

What is the most popular airline from St. Louis to Prague?

Best airlines flying from St. Louis to Prague

Compare and see reviews for airlines that fly from St. Louis to Prague with momondo

Traveling to a place near Prague?

Why use momondo?

Why should I use momondo to find a flight deal from St. Louis to Prague?

Can I find flights from St. Louis to Prague with flexible booking policies on momondo?

How can momondo help me find flights from St. Louis to Prague?

I’m not ready to book a flight from St. Louis to Prague right now. Can momondo alert me if prices change?

An easier way to manage your Prague trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

Find better results for your trip to the Czech Republic

Fly your favorite airline to Prague

Airlines are sorted and displayed according to clicks in the past 7 days on momondo