Which layover airport has the shortest connection time from St. Louis to Prague?

Frankfurt am Main (FRA) has the shortest average layover time for this route: 3h 20m.

Which airport is the most popular layover for flights between St. Louis and Prague?

Frankfurt am Main (FRA) was the most common stop: 72% of momondo users choosing 1-stop flights on this route connected there.

What is the cheapest airline that flies from Lambert-St Louis to Václav Havel Prague?

British Airways is the most popular carrier operating from Lambert-St Louis to Václav Havel Prague

Which layover airport offers the lowest fares from St. Louis to Prague?

Flights via London (LHR) offer the lowest average round-trip price of $714.

Which layover airport has the shortest travel time from St. Louis to Prague?

Flights connecting via Frankfurt am Main (FRA) have the shortest average one-way travel time: 13h 11m.

What airlines fly to Prague?

United Airlines, Lufthansa and Delta are the top three most popular airlines that fly to Prague from St. Louis according to our data. United Airlines is the first choice among our users, with 39% of people opting to fly with this airline when traveling to Prague. Keep in mind that there are 4 different airlines that fly to Prague on a routine basis, so you have a few additional options to choose from.

When did momondo last update prices for flights from Lambert-St Louis Airport to Václav Havel Prague Airport?

Prices for flights from Lambert-St Louis Airport to Václav Havel Prague Airport are refreshed on a daily basis.

How many operators does momondo search for flights from Lambert-St Louis Airport to Václav Havel Prague Airport?

The number of operators available for flights from Lambert-St Louis Airport to Václav Havel Prague Airport is 4 as of January 2026.

How old do you have to be to fly from Lambert-St Louis Airport to Václav Havel Prague Airport?

The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Lambert-St Louis Airport to Václav Havel Prague Airport.

What documentation or ID do you need to fly to Václav Havel Prague Airport?

The travel and health documents you'll need for your trip to Václav Havel Prague Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Václav Havel Prague Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

$341 Cheap Flights from St. Louis to Prague in 2026

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Find the cheapest flights from St. Louis to Prague

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Cheap round-trip flights

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12:11 pm - 3:45 pm

STL

PRG

20h 34m

2 stops

10:10 am - 10:14 pm

PRG

STL

19h 04m

2 stops

$445British Airways

Wed, Apr 29 - Fri, May 8

9:35 pm - 10:55 pm

STL

PRG

18h 20m

1 stop

10:10 am - 10:14 pm

PRG

STL

19h 04m

2 stops

$448British Airways

Wed, Apr 29 - Fri, May 8

5:15 am - 6:50 pm

STL

PRG

31h 35m

2 stops

7:35 pm - 10:58 pm

PRG

STL

33h 23m

2 stops

$461Multiple Airlines

Wed, Mar 18 - Tue, Mar 24

2:00 pm - 9:05 pm

STL

PRG

24h 05m

2 stops

11:00 am - 11:22 pm

PRG

STL

19h 22m

2 stops

$470British Airways

Fri, Feb 27 - Wed, Mar 4

9:35 pm - 5:05 pm

STL

PRG

12h 30m

1 stop

10:10 am - 10:14 pm

PRG

STL

19h 04m

2 stops

$481British Airways

Wed, Apr 29 - Fri, May 8

7:00 am - 6:50 pm

STL

PRG

28h 50m

2 stops

7:35 pm - 7:29 pm

PRG

STL

30h 54m

2 stops

$486Multiple Airlines

Thu, Feb 12 - Mon, Feb 23

12:15 pm - 1:55 pm

STL

PRG

18h 40m

2 stops

7:30 am - 1:55 pm

PRG

STL

13h 25m

1 stop

$487United Airlines

Wed, Feb 25 - Wed, Mar 4

4:05 pm - 5:55 pm

STL

PRG

42h 50m

2 stops

10:25 am - 3:24 pm

PRG

STL

35h 59m

2 stops

$488Multiple Airlines

Sat, Apr 11 - Wed, Apr 22

2:29 pm - 5:20 pm

STL

PRG

19h 51m

2 stops

1:00 pm - 7:30 pm

PRG

STL

13h 30m

1 stop

$492British Airways

Sat, Apr 11 - Wed, Apr 22

12:11 pm - 1:35 pm

STL

PRG

18h 24m

2 stops

6:50 am - 10:14 pm

PRG

STL

22h 24m

2 stops

$495British Airways

Sun, Apr 19 - Sun, Apr 26

American Airlines flights from St. Louis to Prague

Our best American Airlines deals on St. Louis to Prague flight tickets

American Airlines

Mar 1

STL6:38 pmLambert-St Louis

16h 32m

2 stops

PRG6:10 pmVáclav Havel Prague

Mar 17

PRG6:45 amVáclav Havel Prague

19h 31m

2 stops

STL8:16 pmLambert-St Louis

$453

American Airlines

Feb 10

STL12:03 pmLambert-St Louis

17h 52m

2 stops

PRG12:55 pmVáclav Havel Prague

Feb 17

PRG6:45 amVáclav Havel Prague

19h 07m

2 stops

STL6:52 pmLambert-St Louis

$460

Lufthansa flights from St. Louis to Prague

Our best Lufthansa deals on St. Louis to Prague flight tickets

Lufthansa

Mar 1

STL3:50 pmLambert-St Louis

15h 25m

1 stop

PRG2:15 pmVáclav Havel Prague

Mar 17

PRG3:05 pmVáclav Havel Prague

29h 50m

1 stop

STL2:55 pmLambert-St Louis

$515

Lufthansa

Apr 8

STL3:30 pmLambert-St Louis

15h 00m

1 stop

PRG1:30 pmVáclav Havel Prague

Apr 14

PRG6:40 pmVáclav Havel Prague

25h 45m

1 stop

STL1:25 pmLambert-St Louis

$526

Lufthansa

Apr 19

STL3:30 pmLambert-St Louis

12h 25m

1 stop

PRG10:55 amVáclav Havel Prague

Apr 26

PRG6:10 amVáclav Havel Prague

14h 15m

1 stop

STL1:25 pmLambert-St Louis

$550

Fly from

Fly to

Route

Depart

Return

Price

St. LouisPrague

STL - PRG

STLPRG

Lambert-St Louis

Wed 4/29

12:11 pm-3:45 pm

2 stops20h 34m

Václav Havel Prague

Fri 5/8

10:10 am-10:14 pm

2 stops19h 04m

$445

St. LouisPrague

STL - PRG

STLPRG

Lambert-St Louis

Wed 4/29

9:35 pm-10:55 pm

1 stop18h 20m

Václav Havel Prague

Fri 5/8

10:10 am-10:14 pm

2 stops19h 04m

$448

St. LouisPrague

STL - PRG

STLPRG

Lambert-St Louis

Wed 3/18

5:15 am-6:50 pm

2 stops31h 35m

Václav Havel Prague

Tue 3/24

7:35 pm-10:58 pm

2 stops33h 23m

$461

St. LouisPrague

STL - PRG

STLPRG

Lambert-St Louis

Fri 2/27

2:00 pm-9:05 pm

2 stops24h 05m

Václav Havel Prague

Wed 3/4

11:00 am-11:22 pm

2 stops19h 22m

$470

St. LouisPrague

STL - PRG

STLPRG

Lambert-St Louis

Wed 4/29

9:35 pm-5:05 pm

1 stop12h 30m

Václav Havel Prague

Fri 5/8

10:10 am-10:14 pm

2 stops19h 04m

$481

St. LouisPrague

STL - PRG

STLPRG

Lambert-St Louis

Thu 2/12

7:00 am-6:50 pm

2 stops28h 50m

Václav Havel Prague

Mon 2/23

7:35 pm-7:29 pm

2 stops30h 54m

$486

St. LouisPrague

STL - PRG

STLPRG

Lambert-St Louis

Wed 2/25

12:15 pm-1:55 pm

2 stops18h 40m

Václav Havel Prague

Wed 3/4

7:30 am-1:55 pm

1 stop13h 25m

$487

St. LouisPrague

STL - PRG

STLPRG

Lambert-St Louis

Sat 4/11

4:05 pm-5:55 pm

2 stops42h 50m

Václav Havel Prague

Wed 4/22

10:25 am-3:24 pm

2 stops35h 59m

$488

St. LouisPrague

STL - PRG

STLPRG

Lambert-St Louis

Sat 4/11

2:29 pm-5:20 pm

2 stops19h 51m

Václav Havel Prague

Wed 4/22

1:00 pm-7:30 pm

1 stop13h 30m

$492

St. LouisPrague

STL - PRG

STLPRG

Lambert-St Louis

Sun 4/19

12:11 pm-1:35 pm

2 stops18h 24m

Václav Havel Prague

Sun 4/26

6:50 am-10:14 pm

2 stops22h 24m

$495

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from St. Louis to Prague

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Layovers

Can stopping save me money on St. Louis to Prague flights?

You could potentially save up to 33% on your flight if you consider stops on a St. Louis to Prague flight.

When to book flights from St. Louis to Prague

Are you open to changing your travel dates? Check out the ideal times to fly from St. Louis to Prague according to our flight data. Find out which month and days have the cheapest flights.

Estimated round-trip price

Cheap St. Louis to Prague (STL to PRG) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from St. Louis to Prague

Fastest flight time	15h 44m
Direct flights	None

The fastest flight from St. Louis to Prague takes 15h 44m

There are no direct flights from St. Louis to Prague. There are no popular flight routes from St. Louis to Prague.

Search flight deals

How far is Lambert-St Louis to Václav Havel Prague by plane?
Lambert-St Louis and Václav Havel Prague are 4789.6 mi apart from one another. Flights usually cover this in 15h 44m, depending on flying conditions and air traffic around both airports.
When did momondo last update prices for flights from Lambert-St Louis Airport to Václav Havel Prague Airport?
Prices for flights from Lambert-St Louis Airport to Václav Havel Prague Airport are refreshed on a daily basis.
How many operators does momondo search for flights from Lambert-St Louis Airport to Václav Havel Prague Airport?
The number of operators available for flights from Lambert-St Louis Airport to Václav Havel Prague Airport is 4 as of January 2026.
How old do you have to be to fly from Lambert-St Louis Airport to Václav Havel Prague Airport?
The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Lambert-St Louis Airport to Václav Havel Prague Airport.
What documentation or ID do you need to fly to Václav Havel Prague Airport?
The travel and health documents you'll need for your trip to Václav Havel Prague Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Václav Havel Prague Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.
What is the most popular airline from St. Louis to Prague?
momondo data reveals that the most frequently booked airline on the route from St. Louis to Prague is United Airlines, representing 39% of all bookings. The subsequent popular airlines are Lufthansa at 34%, Delta at 15%, and British Airways at 12%.

Best airlines flying from St. Louis to Prague

Compare and see reviews for airlines that fly from St. Louis to Prague with momondo

Airline	Rating	Free Cancellation	Price
United Airlines	PriceFrom $504	Free Cancellation	Rating 7.4 9,152 reviews	Search United Airlines flights
British Airways	PriceFrom $582	Free Cancellation	Rating 6.7 7,669 reviews	Search British Airways flights
Delta	PriceFrom $642	Free Cancellation	Rating 7.9 8,039 reviews	Search Delta flights
Lufthansa	PriceFrom $684	Free Cancellation	Rating 6.8 7,709 reviews	Search Lufthansa flights

Český Krumlov

Pilsen

Liberec

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Why should I use momondo to find a flight deal from St. Louis to Prague?

It is quick and easy to find St. Louis to Prague flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Prague that suits you.

Can I find flights from St. Louis to Prague with flexible booking policies on momondo?

Yes. All flights to Prague from St. Louis on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from St. Louis to Prague?

Once you have performed a search for St. Louis to Prague flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from St. Louis to Prague right now. Can momondo alert me if prices change?

If you are not ready to book a flight from St. Louis to Prague now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Prague and let you know when they change.

An easier way to manage your Prague trip

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Cheap flights from St. Louis to Prague from $341

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from St. Louis to Prague departing on 1/30. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.

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American Airlines flights from St. Louis to Prague

Our best American Airlines deals on St. Louis to Prague flight tickets

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See travel insights to Prague from

How to get the cheapest flight ticket from St. Louis to Prague

Can stopping save me money on St. Louis to Prague flights?

You could potentially save up to 33% on your flight if you consider stops on a St. Louis to Prague flight.

What is the cheapest airline that flies from Lambert-St Louis to Václav Havel Prague?

British Airways is the most popular carrier operating from Lambert-St Louis to Václav Havel Prague

What airlines fly to Prague?

Which airport is the most popular layover for flights between St. Louis and Prague?

Frankfurt am Main (FRA) was the most common stop: 72% of momondo users choosing 1-stop flights on this route connected there.

Which layover airport offers the lowest fares from St. Louis to Prague?

Flights via London (LHR) offer the lowest average round-trip price of $714.

Which layover airport has the shortest travel time from St. Louis to Prague?

Flights connecting via Frankfurt am Main (FRA) have the shortest average one-way travel time: 13h 11m.

Which layover airport has the shortest connection time from St. Louis to Prague?

Frankfurt am Main (FRA) has the shortest average layover time for this route: 3h 20m.

When to book flights from St. Louis to Prague

Cheap St. Louis to Prague (STL to PRG) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from St. Louis to Prague

Fastest flight time

Direct flights

How far is Lambert-St Louis to Václav Havel Prague by plane?

When did momondo last update prices for flights from Lambert-St Louis Airport to Václav Havel Prague Airport?

How many operators does momondo search for flights from Lambert-St Louis Airport to Václav Havel Prague Airport?

How old do you have to be to fly from Lambert-St Louis Airport to Václav Havel Prague Airport?

What documentation or ID do you need to fly to Václav Havel Prague Airport?

What is the most popular airline from St. Louis to Prague?

Best airlines flying from St. Louis to Prague

Compare and see reviews for airlines that fly from St. Louis to Prague with momondo

Traveling to a place near Prague?

Why use momondo?

Why should I use momondo to find a flight deal from St. Louis to Prague?

Can I find flights from St. Louis to Prague with flexible booking policies on momondo?

How can momondo help me find flights from St. Louis to Prague?

I’m not ready to book a flight from St. Louis to Prague right now. Can momondo alert me if prices change?

An easier way to manage your Prague trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

Find better results for your trip to the Czech Republic

Fly your favorite airline to Prague

Airlines are sorted and displayed according to clicks in the past 7 days on momondo