Which layover airport has the shortest travel time from St. Louis to Prague?

Flights connecting via Frankfurt am Main (FRA) have the shortest average one-way travel time: 13h 11m.

What airlines fly to Prague?

Lufthansa, United Airlines and Delta are the top three most popular airlines that fly to Prague from St. Louis according to our data. Lufthansa is the first choice among our users, with 38% of people opting to fly with this airline when traveling to Prague. Keep in mind that there are 4 different airlines that fly to Prague on a routine basis, so you have a few additional options to choose from.

Which airport is the most popular layover for flights between St. Louis and Prague?

Frankfurt am Main (FRA) was the most common stop: 74% of momondo users choosing 1-stop flights on this route connected there.

Which layover airport has the shortest connection time from St. Louis to Prague?

Frankfurt am Main (FRA) has the shortest average layover time for this route: 3h 08m.

Which layover airport offers the lowest fares from St. Louis to Prague?

Flights via Frankfurt am Main (FRA) offer the lowest average round-trip price of $711.

What is the cheapest airline that flies from Lambert-St Louis to Václav Havel Prague?

Delta, United Airlines, and Iberia are the most popular carriers operating from Lambert-St Louis to Václav Havel Prague

When did momondo last update prices for flights from Lambert-St Louis Airport to Václav Havel Prague Airport?

Prices for flights from Lambert-St Louis Airport to Václav Havel Prague Airport are refreshed on a daily basis.

How many operators does momondo search for flights from Lambert-St Louis Airport to Václav Havel Prague Airport?

The number of operators available for flights from Lambert-St Louis Airport to Václav Havel Prague Airport is 4 as of September 2026.

How old do you have to be to fly from Lambert-St Louis Airport to Václav Havel Prague Airport?

The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Lambert-St Louis Airport to Václav Havel Prague Airport.

What documentation or ID do you need to fly to Václav Havel Prague Airport?

The travel and health documents you'll need for your trip to Václav Havel Prague Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Václav Havel Prague Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

$332 Cheap Flights from St. Louis to Prague in 2026

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from St. Louis to Prague

Round-trip

One-way

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Cheap round-trip flights

Enter your travel dates to find the best prices.

5:29 pm - 5:20 pmSTL Lambert-St Louis-PRG Václav Havel Prague

16h 51m2 stops Chicago O'Hare Intl London Heathrow

9:30 pm - 11:33 pmPRG Václav Havel Prague-STL Lambert-St Louis

33h 03m2 stops London Heathrow Dallas/Fort Worth

$658British Airways

Wed, Nov 18 - Wed, Dec 2

7:24 am - 6:50 pmSTL Lambert-St Louis-PRG Václav Havel Prague

28h 26m2 stops Dallas/Fort Worth Helsinki-Vantaa

7:35 pm - 9:47 pmPRG Václav Havel Prague-STL Lambert-St Louis

33h 12m2 stops Helsinki-Vantaa Miami

$675Multiple Airlines

Wed, Nov 18 - Wed, Dec 2

4:40 pm - 9:40 amSTL Lambert-St Louis-PRG Václav Havel Prague

11h 00m1 stop Frankfurt am Main

7:05 am - 9:40 pmPRG Václav Havel Prague-STL Lambert-St Louis

21h 35m2 stops Frankfurt am Main Chicago O'Hare Intl

$736Lufthansa

Wed, Oct 28 - Mon, Nov 2

3:40 pm - 2:00 pmSTL Lambert-St Louis-PRG Václav Havel Prague

15h 20m1 stop Frankfurt am Main

7:05 am - 1:45 pmPRG Václav Havel Prague-STL Lambert-St Louis

13h 40m1 stop Frankfurt am Main

$741Lufthansa

Wed, Nov 18 - Wed, Dec 2

3:40 pm - 9:40 amSTL Lambert-St Louis-PRG Václav Havel Prague

11h 00m1 stop Frankfurt am Main

2:50 pm - 2:26 pmPRG Václav Havel Prague-STL Lambert-St Louis

30h 36m2 stops Frankfurt am Main Chicago O'Hare Intl

$741United Airlines

Wed, Nov 18 - Wed, Dec 2

4:50 pm - 10:50 amSTL Lambert-St Louis-PRG Václav Havel Prague

35h 00m2 stops Newark Toronto Pearson Intl

6:10 am - 1:25 pmPRG Václav Havel Prague-STL Lambert-St Louis

14h 15m1 stop Frankfurt am Main

$761United Airlines

Mon, Oct 5 - Tue, Oct 13

6:00 pm - 5:05 pmSTL Lambert-St Louis-PRG Václav Havel Prague

16h 05m2 stops Detroit Metropolitan Wayne County Paris Charles de Gaulle

6:30 am - 11:26 pmPRG Václav Havel Prague-STL Lambert-St Louis

23h 56m2 stops Paris Charles de Gaulle Minneapolis St Paul

$796Delta

Sat, Nov 28 - Sat, Dec 5

4:22 pm - 6:05 pmSTL Lambert-St Louis-PRG Václav Havel Prague

18h 43m2 stops Detroit Metropolitan Wayne County Paris Charles de Gaulle

6:30 am - 9:25 pmPRG Václav Havel Prague-STL Lambert-St Louis

20h 55m2 stops Paris Charles de Gaulle Minneapolis St Paul

$850Delta

Sat, Oct 24 - Sat, Oct 31

7:27 am - 8:15 amSTL Lambert-St Louis-PRG Václav Havel Prague

17h 48m2 stops Chicago O'Hare Intl Philadelphia

7:15 am - 8:57 pmPRG Václav Havel Prague-STL Lambert-St Louis

20h 42m2 stops London Heathrow Chicago O'Hare Intl

$879American Airlines

Sat, Sep 26 - Mon, Oct 5

9:35 pm - 10:55 pmSTL Lambert-St Louis-PRG Václav Havel Prague

18h 20m1 stop London Heathrow

10:15 am - 10:42 pmPRG Václav Havel Prague-STL Lambert-St Louis

19h 27m2 stops Philadelphia Charlotte Douglas

$1,119American Airlines

Wed, Sep 23 - Tue, Sep 29

Cheap last minute flights

Enter your travel dates to find the best prices.

8:55 am - 4:00 pmSTL Lambert-St Louis-PRG Václav Havel Prague

24h 05m2 stops Toronto Pearson Intl Munich Franz Josef Strauss

12:30 pm - 2:17 pmPRG Václav Havel Prague-STL Lambert-St Louis

32h 47m2 stops Toronto Pearson Intl Chicago O'Hare Intl

$994Air Canada

Mon, Sep 14 - Wed, Sep 23

2:40 pm - 8:15 amSTL Lambert-St Louis-PRG Václav Havel Prague

34h 35m2 stops Toronto Pearson Intl Zurich

12:30 pm - 3:43 pmPRG Václav Havel Prague-STL Lambert-St Louis

34h 13m2 stops Toronto Pearson Intl Chicago O'Hare Intl

$995Air Canada

Sun, Sep 13 - Wed, Sep 23

10:29 am - 9:00 amSTL Lambert-St Louis-PRG Václav Havel Prague

15h 31m2 stops Detroit Metropolitan Wayne County New York John F Kennedy Intl

11:00 am - 8:35 pmPRG Václav Havel Prague-STL Lambert-St Louis

16h 35m2 stops New York John F Kennedy Intl Detroit Metropolitan Wayne County

$1,002Delta

Mon, Sep 14 - Tue, Sep 22

3:32 pm - 4:00 pmSTL Lambert-St Louis-PRG Václav Havel Prague

17h 28m2 stops Chicago O'Hare Intl Munich Franz Josef Strauss

6:10 am - 1:25 pmPRG Václav Havel Prague-STL Lambert-St Louis

14h 15m1 stop Frankfurt am Main

$1,003United Airlines

Mon, Sep 14 - Tue, Sep 22

3:32 pm - 4:00 pmSTL Lambert-St Louis-PRG Václav Havel Prague

17h 28m2 stops Chicago O'Hare Intl Munich Franz Josef Strauss

12:30 pm - 8:20 pmPRG Václav Havel Prague-STL Lambert-St Louis

14h 50m1 stop Toronto Pearson Intl

$1,003United Airlines

Mon, Sep 14 - Wed, Sep 23

1:40 pm - 7:35 pmSTL Lambert-St Louis-PRG Václav Havel Prague

22h 55m2 stops Atlanta Hartsfield-Jackson Paris Charles de Gaulle

11:00 am - 8:35 pmPRG Václav Havel Prague-STL Lambert-St Louis

16h 35m2 stops New York John F Kennedy Intl Detroit Metropolitan Wayne County

$1,006Delta

Sun, Sep 13 - Tue, Sep 22

3:30 pm - 5:55 pmSTL Lambert-St Louis-PRG Václav Havel Prague

19h 25m1 stop Frankfurt am Main

6:10 am - 1:25 pmPRG Václav Havel Prague-STL Lambert-St Louis

14h 15m1 stop Frankfurt am Main

$1,015Lufthansa

Sun, Sep 13 - Tue, Sep 22

3:30 pm - 10:45 amSTL Lambert-St Louis-PRG Václav Havel Prague

12h 15m1 stop Frankfurt am Main

6:10 am - 1:25 pmPRG Václav Havel Prague-STL Lambert-St Louis

14h 15m1 stop Frankfurt am Main

$1,015Lufthansa

Sun, Sep 13 - Wed, Sep 23

6:30 am - 8:15 amSTL Lambert-St Louis-PRG Václav Havel Prague

18h 45m1 stop Philadelphia

10:15 am - 9:44 pmPRG Václav Havel Prague-STL Lambert-St Louis

18h 29m1 stop Philadelphia

$1,056American Airlines

Wed, Sep 16 - Wed, Sep 23

7:21 am - 8:15 amSTL Lambert-St Louis-PRG Václav Havel Prague

17h 54m2 stops Chicago O'Hare Intl Philadelphia

10:15 am - 9:44 pmPRG Václav Havel Prague-STL Lambert-St Louis

18h 29m1 stop Philadelphia

$1,060American Airlines

Wed, Sep 16 - Wed, Sep 23

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Lufthansa flights from St. Louis to Prague

Our best Lufthansa deals on St. Louis to Prague flight tickets

Lufthansa

Oct 28

STL4:40 pmLambert-St Louis

11h 00m

1 stop

PRG9:40 amVáclav Havel Prague

Nov 2

PRG7:05 amVáclav Havel Prague

21h 35m

2 stops

STL9:40 pmLambert-St Louis

$736

Lufthansa

Sep 19

STL4:40 pmLambert-St Louis

37h 00m

2 stops

PRG12:40 pmVáclav Havel Prague

Sep 30

PRG12:30 pmVáclav Havel Prague

14h 50m

1 stop

STL8:20 pmLambert-St Louis

$773

Lufthansa

Oct 5

STL3:30 pmLambert-St Louis

19h 10m

1 stop

PRG5:40 pmVáclav Havel Prague

Oct 13

PRG6:10 amVáclav Havel Prague

14h 15m

1 stop

STL1:25 pmLambert-St Louis

$785

Air Canada flights from St. Louis to Prague

Our best Air Canada deals on St. Louis to Prague flight tickets

Air Canada

Oct 28

STL4:05 pmLambert-St Louis

18h 00m

2 stops

PRG4:05 pmVáclav Havel Prague

Nov 2

PRG10:20 amVáclav Havel Prague

18h 20m

3 stops

STL9:40 pmLambert-St Louis

$739

Air Canada

Oct 18

STL12:10 pmLambert-St Louis

20h 50m

2 stops

PRG4:00 pmVáclav Havel Prague

Nov 3

PRG11:30 amVáclav Havel Prague

34h 56m

2 stops

STL3:26 pmLambert-St Louis

$824

Air Canada

Oct 18

STL2:40 pmLambert-St Louis

13h 10m

1 stop

PRG10:50 amVáclav Havel Prague

Nov 3

PRG7:05 amVáclav Havel Prague

39h 21m

2 stops

STL3:26 pmLambert-St Louis

$826

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

St. LouisPrague

STL Lambert-St Louis - PRG Václav Havel Prague

STLPRG

Lambert-St Louis

Wed 11/18

5:29 pm-5:20 pm

2 stops16h 51m

Václav Havel Prague

Wed 12/2

9:30 pm-11:33 pm

2 stops33h 03m

$658

St. LouisPrague

STL Lambert-St Louis - PRG Václav Havel Prague

STLPRG

Lambert-St Louis

Wed 11/18

7:24 am-6:50 pm

2 stops28h 26m

Václav Havel Prague

Wed 12/2

7:35 pm-9:47 pm

2 stops33h 12m

$675

St. LouisPrague

STL Lambert-St Louis - PRG Václav Havel Prague

STLPRG

Lambert-St Louis

Wed 10/28

4:40 pm-9:40 am

1 stop11h 00m

Václav Havel Prague

Mon 11/2

7:05 am-9:40 pm

2 stops21h 35m

$736

Quickest round-trip

St. LouisPrague

STL Lambert-St Louis - PRG Václav Havel Prague

STLPRG

Lambert-St Louis

Wed 11/18

3:40 pm-2:00 pm

1 stop15h 20m

Václav Havel Prague

Wed 12/2

7:05 am-1:45 pm

1 stop13h 40m

$741

St. LouisPrague

STL Lambert-St Louis - PRG Václav Havel Prague

STLPRG

Lambert-St Louis

Wed 11/18

3:40 pm-9:40 am

1 stop11h 00m

Václav Havel Prague

Wed 12/2

2:50 pm-2:26 pm

2 stops30h 36m

$741

St. LouisPrague

STL Lambert-St Louis - PRG Václav Havel Prague

STLPRG

Lambert-St Louis

Mon 10/5

4:50 pm-10:50 am

2 stops35h 00m

Václav Havel Prague

Tue 10/13

6:10 am-1:25 pm

1 stop14h 15m

$761

St. LouisPrague

STL Lambert-St Louis - PRG Václav Havel Prague

STLPRG

Lambert-St Louis

Sat 11/28

6:00 pm-5:05 pm

2 stops16h 05m

Václav Havel Prague

Sat 12/5

6:30 am-11:26 pm

2 stops23h 56m

$796

St. LouisPrague

STL Lambert-St Louis - PRG Václav Havel Prague

STLPRG

Lambert-St Louis

Sat 10/24

4:22 pm-6:05 pm

2 stops18h 43m

Václav Havel Prague

Sat 10/31

6:30 am-9:25 pm

2 stops20h 55m

$850

St. LouisPrague

STL Lambert-St Louis - PRG Václav Havel Prague

STLPRG

Lambert-St Louis

Sat 9/26

7:27 am-8:15 am

2 stops17h 48m

Václav Havel Prague

Mon 10/5

7:15 am-8:57 pm

2 stops20h 42m

$879

St. LouisPrague

STL Lambert-St Louis - PRG Václav Havel Prague

STLPRG

Lambert-St Louis

Wed 9/23

9:35 pm-10:55 pm

1 stop18h 20m

Václav Havel Prague

Tue 9/29

10:15 am-10:42 pm

2 stops19h 27m

$1,119

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from St. Louis to Prague

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Layovers

What is the typical price of a round-trip flight between St. Louis and Prague?

Prices are currently low for flights on this route.

Typical prices usually range from $726 to $1,001.
The lowest price recently found on this route was $658.

What is the cheapest month to fly to Prague?

In general, January is the cheapest month to fly from St. Louis to Prague. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $0. If you are unable to visit Prague during the month of January, then departing from St. Louis during the month April is also very affordable. Most momondo users find prices during this month for around $620.

Can stopping save me money on St. Louis to Prague flights?

You could potentially save up to 17% on your flight if you consider stops on a St. Louis to Prague flight.

When to book flights from St. Louis to Prague

Are you open to changing your travel dates? Check out the ideal times to fly from St. Louis to Prague according to our flight data. Find out which month and days have the cheapest flights.

Estimated round-trip price

Cheap St. Louis to Prague (STL to PRG) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from St. Louis to Prague

Best Price Found	$332
Fastest flight time	19h 20m
Direct flights	None

The best one-way flight to Prague from St. Louis in the past 72 hours is $332. The best round-trip flight deal from St. Louis to Prague found on momondo in the last 72 hours is $658.

The fastest flight from St. Louis to Prague takes 19h 20m

There are no direct flights from St. Louis to Prague. There are no popular flight routes from St. Louis to Prague.

Search flight deals

Frequently asked questions about flying from St. Louis to Prague

How far is Lambert-St Louis to Václav Havel Prague by plane?
Lambert-St Louis and Václav Havel Prague are 4789.6 mi apart from one another. Flights usually cover this in 19h 20m, depending on flying conditions and air traffic around both airports.
When did momondo last update prices for flights from Lambert-St Louis Airport to Václav Havel Prague Airport?
Prices for flights from Lambert-St Louis Airport to Václav Havel Prague Airport are refreshed on a daily basis.
How many operators does momondo search for flights from Lambert-St Louis Airport to Václav Havel Prague Airport?
The number of operators available for flights from Lambert-St Louis Airport to Václav Havel Prague Airport is 4 as of September 2026.
How old do you have to be to fly from Lambert-St Louis Airport to Václav Havel Prague Airport?
The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Lambert-St Louis Airport to Václav Havel Prague Airport.
What documentation or ID do you need to fly to Václav Havel Prague Airport?
The travel and health documents you'll need for your trip to Václav Havel Prague Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Václav Havel Prague Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.
What is the most popular airline from St. Louis to Prague?
momondo data reveals that the most frequently booked airline on the route from St. Louis to Prague is Lufthansa, representing 38% of all bookings. The subsequent popular airlines are United Airlines at 26%, Delta at 21%, and American Airlines at 15%.

Best airlines flying from St. Louis to Prague

Compare and see reviews for airlines that fly from St. Louis to Prague with momondo

Airline	Rating	Free Cancellation	Price
United Airlines	PriceFrom $500	Free Cancellation	Rating 7.4 10,194 reviews	Search United Airlines flights
American Airlines	PriceFrom $511	Free Cancellation	Rating 7.1 12,045 reviews	Search American Airlines flights
Lufthansa	PriceFrom $572	Free Cancellation	Rating 6.8 8,212 reviews	Search Lufthansa flights
Delta	PriceFrom $928	Free Cancellation	Rating 7.8 8,554 reviews	Search Delta flights

Český Krumlov

Pilsen

Liberec

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Why should I use momondo to find a flight deal from St. Louis to Prague?

It is quick and easy to find St. Louis to Prague flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Prague that suits you.

Can I find flights from St. Louis to Prague with flexible booking policies on momondo?

Yes. All flights to Prague from St. Louis on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from St. Louis to Prague?

Once you have performed a search for St. Louis to Prague flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from St. Louis to Prague right now. Can momondo alert me if prices change?

If you are not ready to book a flight from St. Louis to Prague now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Prague and let you know when they change.

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Cheap flights from St. Louis to Prague from $332

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from St. Louis to Prague departing on 11/2. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.

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Lufthansa flights from St. Louis to Prague

Our best Lufthansa deals on St. Louis to Prague flight tickets

Air Canada flights from St. Louis to Prague

Our best Air Canada deals on St. Louis to Prague flight tickets

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How to get the cheapest flight ticket from St. Louis to Prague

What is the typical price of a round-trip flight between St. Louis and Prague?

What is the cheapest month to fly to Prague?

Can stopping save me money on St. Louis to Prague flights?

What is the cheapest airline that flies from Lambert-St Louis to Václav Havel Prague?

What airlines fly to Prague?

Which airport is the most popular layover for flights between St. Louis and Prague?

Which layover airport offers the lowest fares from St. Louis to Prague?

Which layover airport has the shortest travel time from St. Louis to Prague?

Which layover airport has the shortest connection time from St. Louis to Prague?

When to book flights from St. Louis to Prague

Cheap St. Louis to Prague (STL to PRG) flight deals and tips

Best Price Found

Fastest flight time

Direct flights

Frequently asked questions about flying from St. Louis to Prague

Best airlines flying from St. Louis to Prague

Compare and see reviews for airlines that fly from St. Louis to Prague with momondo

Traveling to a place near Prague?

Why use momondo?

An easier way to manage your Prague trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

Find better results for your trip to the Czech Republic

Fly your favorite airline to Prague

Airlines are sorted and displayed according to clicks in the past 7 days on momondo

Cabin classes currently available on flights to Prague

List of cabin classes available on flights landing in Prague. Availability may vary depending on flight origin and airline.

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Popular flights according to clicks in the last 7 days on momondo

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According to popular flight searches on momondo this year

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