Which airport is the most popular layover for flights between St. Louis and Prague?

Frankfurt am Main (FRA) was the most common stop: 74% of momondo users choosing 1-stop flights on this route connected there.

What airlines fly to Prague?

Lufthansa, United Airlines and Delta are the top three most popular airlines that fly to Prague from St. Louis according to our data. Lufthansa is the first choice among our users, with 39% of people opting to fly with this airline when traveling to Prague. Keep in mind that there are 4 different airlines that fly to Prague on a routine basis, so you have a few additional options to choose from.

Which layover airport has the shortest connection time from St. Louis to Prague?

Frankfurt am Main (FRA) has the shortest average layover time for this route: 3h 08m.

Which layover airport offers the lowest fares from St. Louis to Prague?

Flights via Frankfurt am Main (FRA) offer the lowest average round-trip price of $711.

Which layover airport has the shortest travel time from St. Louis to Prague?

Flights connecting via Frankfurt am Main (FRA) have the shortest average one-way travel time: 13h 11m.

What is the cheapest airline that flies from Lambert-St Louis to Václav Havel Prague?

Delta is the most popular carrier operating from Lambert-St Louis to Václav Havel Prague

When did momondo last update prices for flights from Lambert-St Louis Airport to Václav Havel Prague Airport?

Prices for flights from Lambert-St Louis Airport to Václav Havel Prague Airport are refreshed on a daily basis.

How many operators does momondo search for flights from Lambert-St Louis Airport to Václav Havel Prague Airport?

The number of operators available for flights from Lambert-St Louis Airport to Václav Havel Prague Airport is 4 as of August 2026.

How old do you have to be to fly from Lambert-St Louis Airport to Václav Havel Prague Airport?

The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Lambert-St Louis Airport to Václav Havel Prague Airport.

What documentation or ID do you need to fly to Václav Havel Prague Airport?

The travel and health documents you'll need for your trip to Václav Havel Prague Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Václav Havel Prague Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

$375 Cheap Flights from St. Louis to Prague in 2026

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from St. Louis to Prague

Round-trip

One-way

Cheap round-trip flights

Enter your travel dates to find the best prices.

6:50 pm - 4:05 pmSTL Lambert-St Louis-PRG Václav Havel Prague

14h 15m2 stops Chicago O'Hare Intl Munich Franz Josef Strauss

7:05 am - 1:45 pmPRG Václav Havel Prague-STL Lambert-St Louis

13h 40m1 stop Frankfurt am Main

$795Lufthansa

Mon, Nov 30 - Fri, Dec 18

6:50 pm - 4:05 pmSTL Lambert-St Louis-PRG Václav Havel Prague

14h 15m2 stops Chicago O'Hare Intl Munich Franz Josef Strauss

7:05 am - 1:45 pmPRG Václav Havel Prague-STL Lambert-St Louis

13h 40m1 stop Frankfurt am Main

$796Lufthansa

Mon, Nov 30 - Sun, Dec 6

6:50 pm - 4:05 pmSTL Lambert-St Louis-PRG Václav Havel Prague

14h 15m2 stops Chicago O'Hare Intl Munich Franz Josef Strauss

6:10 am - 1:45 pmPRG Václav Havel Prague-STL Lambert-St Louis

14h 35m2 stops Munich Franz Josef Strauss Frankfurt am Main

$798Lufthansa

Mon, Nov 30 - Sun, Dec 6

6:50 pm - 4:05 pmSTL Lambert-St Louis-PRG Václav Havel Prague

14h 15m2 stops Chicago O'Hare Intl Munich Franz Josef Strauss

7:05 am - 3:26 pmPRG Václav Havel Prague-STL Lambert-St Louis

39h 21m2 stops Frankfurt am Main Toronto Pearson Intl

$803Multiple Airlines

Mon, Nov 30 - Fri, Dec 18

12:10 pm - 4:00 pmSTL Lambert-St Louis-PRG Václav Havel Prague

20h 50m2 stops Montreal Pierre Elliott Trudeau Intl Munich Franz Josef Strauss

10:20 am - 3:26 pmPRG Václav Havel Prague-STL Lambert-St Louis

36h 06m2 stops Frankfurt am Main Toronto Pearson Intl

$837Air Canada

Sun, Oct 18 - Tue, Nov 3

8:55 am - 10:50 amSTL Lambert-St Louis-PRG Václav Havel Prague

18h 55m1 stop Toronto Pearson Intl

2:50 pm - 3:26 pmPRG Václav Havel Prague-STL Lambert-St Louis

31h 36m2 stops Frankfurt am Main Toronto Pearson Intl

$841Air Canada

Sun, Oct 18 - Tue, Nov 3

8:05 am - 9:40 amSTL Lambert-St Louis-PRG Václav Havel Prague

18h 35m2 stops Chicago O'Hare Intl Frankfurt am Main

11:30 am - 2:30 pmPRG Václav Havel Prague-STL Lambert-St Louis

34h 00m2 stops Frankfurt am Main Chicago O'Hare Intl

$890United Airlines

Sun, Dec 27 - Tue, Jan 5

7:30 am - 9:20 pmSTL Lambert-St Louis-PRG Václav Havel Prague

30h 50m3 stops Newark Boston Logan Intl Munich Franz Josef Strauss

6:00 am - 6:41 pmPRG Václav Havel Prague-STL Lambert-St Louis

19h 41m2 stops Frankfurt am Main Montreal Pierre Elliott Trudeau Intl

$951United Airlines

Thu, Oct 8 - Thu, Oct 15

6:30 am - 8:15 amSTL Lambert-St Louis-PRG Václav Havel Prague

18h 45m1 stop Philadelphia

10:15 am - 9:43 pmPRG Václav Havel Prague-STL Lambert-St Louis

18h 28m1 stop Philadelphia

$1,048American Airlines

Thu, Sep 10 - Fri, Sep 18

11:09 am - 8:15 amSTL Lambert-St Louis-PRG Václav Havel Prague

14h 06m1 stop Philadelphia

10:15 am - 9:43 pmPRG Václav Havel Prague-STL Lambert-St Louis

18h 28m1 stop Philadelphia

$1,048American Airlines

Thu, Sep 10 - Fri, Sep 18

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Lufthansa flights from St. Louis to Prague

Our best Lufthansa deals on St. Louis to Prague flight tickets

Lufthansa

Nov 30

STL6:50 pmLambert-St Louis

14h 15m

2 stops

PRG4:05 pmVáclav Havel Prague

Dec 6

PRG7:05 amVáclav Havel Prague

13h 40m

1 stop

STL1:45 pmLambert-St Louis

$796

Lufthansa

Nov 30

STL6:50 pmLambert-St Louis

14h 15m

2 stops

PRG4:05 pmVáclav Havel Prague

Dec 6

PRG6:10 amVáclav Havel Prague

14h 35m

2 stops

STL1:45 pmLambert-St Louis

$798

Lufthansa

Nov 18

STL3:40 pmLambert-St Louis

11h 00m

1 stop

PRG9:40 amVáclav Havel Prague

Dec 2

PRG7:00 pmVáclav Havel Prague

34h 15m

2 stops

STL10:15 pmLambert-St Louis

$884

American Airlines flights from St. Louis to Prague

Our best American Airlines deals on St. Louis to Prague flight tickets

American Airlines

Sep 10

STL6:30 amLambert-St Louis

18h 45m

1 stop

PRG8:15 amVáclav Havel Prague

Sep 18

PRG10:15 amVáclav Havel Prague

18h 28m

1 stop

STL9:43 pmLambert-St Louis

$1,048

American Airlines

Sep 10

STL8:30 amLambert-St Louis

16h 45m

2 stops

PRG8:15 amVáclav Havel Prague

Sep 18

PRG10:15 amVáclav Havel Prague

19h 27m

2 stops

STL10:42 pmLambert-St Louis

$1,052

American Airlines

Sep 10

STL8:30 amLambert-St Louis

16h 45m

2 stops

PRG8:15 amVáclav Havel Prague

Sep 18

PRG10:15 amVáclav Havel Prague

19h 27m

2 stops

STL10:42 pmLambert-St Louis

$1,053

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Quickest round-trip

St. LouisPrague

STL Lambert-St Louis - PRG Václav Havel Prague

STLPRG

Lambert-St Louis

Mon 11/30

6:50 pm-4:05 pm

2 stops14h 15m

Václav Havel Prague

Fri 12/18

7:05 am-1:45 pm

1 stop13h 40m

$795

St. LouisPrague

STL Lambert-St Louis - PRG Václav Havel Prague

STLPRG

Lambert-St Louis

Mon 11/30

6:50 pm-4:05 pm

2 stops14h 15m

Václav Havel Prague

Sun 12/6

7:05 am-1:45 pm

1 stop13h 40m

$796

St. LouisPrague

STL Lambert-St Louis - PRG Václav Havel Prague

STLPRG

Lambert-St Louis

Mon 11/30

6:50 pm-4:05 pm

2 stops14h 15m

Václav Havel Prague

Sun 12/6

6:10 am-1:45 pm

2 stops14h 35m

$798

St. LouisPrague

STL Lambert-St Louis - PRG Václav Havel Prague

STLPRG

Lambert-St Louis

Mon 11/30

6:50 pm-4:05 pm

2 stops14h 15m

Václav Havel Prague

Fri 12/18

7:05 am-3:26 pm

2 stops39h 21m

$803

St. LouisPrague

STL Lambert-St Louis - PRG Václav Havel Prague

STLPRG

Lambert-St Louis

Sun 10/18

12:10 pm-4:00 pm

2 stops20h 50m

Václav Havel Prague

Tue 11/3

10:20 am-3:26 pm

2 stops36h 06m

$837

St. LouisPrague

STL Lambert-St Louis - PRG Václav Havel Prague

STLPRG

Lambert-St Louis

Sun 10/18

8:55 am-10:50 am

1 stop18h 55m

Václav Havel Prague

Tue 11/3

2:50 pm-3:26 pm

2 stops31h 36m

$841

St. LouisPrague

STL Lambert-St Louis - PRG Václav Havel Prague

STLPRG

Lambert-St Louis

Sun 12/27

8:05 am-9:40 am

2 stops18h 35m

Václav Havel Prague

Tue 1/5

11:30 am-2:30 pm

2 stops34h 00m

$890

St. LouisPrague

STL Lambert-St Louis - PRG Václav Havel Prague

STLPRG

Lambert-St Louis

Thu 10/8

7:30 am-9:20 pm

3 stops30h 50m

Václav Havel Prague

Thu 10/15

6:00 am-6:41 pm

2 stops19h 41m

$951

St. LouisPrague

STL Lambert-St Louis - PRG Václav Havel Prague

STLPRG

Lambert-St Louis

Thu 9/10

6:30 am-8:15 am

1 stop18h 45m

Václav Havel Prague

Fri 9/18

10:15 am-9:43 pm

1 stop18h 28m

$1,048

St. LouisPrague

STL Lambert-St Louis - PRG Václav Havel Prague

STLPRG

Lambert-St Louis

Thu 9/10

11:09 am-8:15 am

1 stop14h 06m

Václav Havel Prague

Fri 9/18

10:15 am-9:43 pm

1 stop18h 28m

$1,048

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from St. Louis to Prague

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Layovers

What is the typical price of a round-trip flight between St. Louis and Prague?

Prices are currently typical for flights on this route.

Typical prices usually range from $726 to $1,013.
The lowest price recently found on this route was $796.

What is the cheapest month to fly to Prague?

In general, January is the cheapest month to fly from St. Louis to Prague. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $0. If you are unable to visit Prague during the month of January, then departing from St. Louis during the month April is also very affordable. Most momondo users find prices during this month for around $620.

Can stopping save me money on St. Louis to Prague flights?

You could potentially save up to 17% on your flight if you consider stops on a St. Louis to Prague flight.

When to book flights from St. Louis to Prague

Are you open to changing your travel dates? Check out the ideal times to fly from St. Louis to Prague according to our flight data. Find out which month and days have the cheapest flights.

Estimated round-trip price

Cheap St. Louis to Prague (STL to PRG) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from St. Louis to Prague

Best Price Found	$375
Fastest flight time	14h 15m
Direct flights	None

The best one-way flight to Prague from St. Louis in the past 72 hours is $375. The best round-trip flight deal from St. Louis to Prague found on momondo in the last 72 hours is $795.

The fastest flight from St. Louis to Prague takes 14h 15m

There are no direct flights from St. Louis to Prague. There are no popular flight routes from St. Louis to Prague.

Search flight deals

Frequently asked questions about flying from St. Louis to Prague

How far is Lambert-St Louis to Václav Havel Prague by plane?
Lambert-St Louis and Václav Havel Prague are 4789.6 mi apart from one another. Flights usually cover this in 14h 15m, depending on flying conditions and air traffic around both airports.
When did momondo last update prices for flights from Lambert-St Louis Airport to Václav Havel Prague Airport?
Prices for flights from Lambert-St Louis Airport to Václav Havel Prague Airport are refreshed on a daily basis.
How many operators does momondo search for flights from Lambert-St Louis Airport to Václav Havel Prague Airport?
The number of operators available for flights from Lambert-St Louis Airport to Václav Havel Prague Airport is 4 as of August 2026.
How old do you have to be to fly from Lambert-St Louis Airport to Václav Havel Prague Airport?
The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Lambert-St Louis Airport to Václav Havel Prague Airport.
What documentation or ID do you need to fly to Václav Havel Prague Airport?
The travel and health documents you'll need for your trip to Václav Havel Prague Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Václav Havel Prague Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.
What is the most popular airline from St. Louis to Prague?
momondo data reveals that the most frequently booked airline on the route from St. Louis to Prague is Lufthansa, representing 39% of all bookings. The subsequent popular airlines are United Airlines at 26%, Delta at 19%, and American Airlines at 16%.

Best airlines flying from St. Louis to Prague

Compare and see reviews for airlines that fly from St. Louis to Prague with momondo

Airline	Rating	Free Cancellation	Price
United Airlines	PriceFrom $500	Free Cancellation	Rating 7.4 10,132 reviews	Search United Airlines flights
American Airlines	PriceFrom $511	Free Cancellation	Rating 7.1 12,013 reviews	Search American Airlines flights
Lufthansa	PriceFrom $572	Free Cancellation	Rating 6.8 8,222 reviews	Search Lufthansa flights
Delta	PriceFrom $908	Free Cancellation	Rating 7.8 8,531 reviews	Search Delta flights

Český Krumlov

Pilsen

Liberec

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Why should I use momondo to find a flight deal from St. Louis to Prague?

It is quick and easy to find St. Louis to Prague flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Prague that suits you.

Can I find flights from St. Louis to Prague with flexible booking policies on momondo?

Yes. All flights to Prague from St. Louis on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from St. Louis to Prague?

Once you have performed a search for St. Louis to Prague flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from St. Louis to Prague right now. Can momondo alert me if prices change?

If you are not ready to book a flight from St. Louis to Prague now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Prague and let you know when they change.

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Cheap flights from St. Louis to Prague from $375

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from St. Louis to Prague departing on 11/23. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.

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Lufthansa flights from St. Louis to Prague

Our best Lufthansa deals on St. Louis to Prague flight tickets

American Airlines flights from St. Louis to Prague

Our best American Airlines deals on St. Louis to Prague flight tickets

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See travel insights to Prague from

How to get the cheapest flight ticket from St. Louis to Prague

What is the typical price of a round-trip flight between St. Louis and Prague?

What is the cheapest month to fly to Prague?

Can stopping save me money on St. Louis to Prague flights?

What is the cheapest airline that flies from Lambert-St Louis to Václav Havel Prague?

What airlines fly to Prague?

Which airport is the most popular layover for flights between St. Louis and Prague?

Which layover airport offers the lowest fares from St. Louis to Prague?

Which layover airport has the shortest travel time from St. Louis to Prague?

Which layover airport has the shortest connection time from St. Louis to Prague?

When to book flights from St. Louis to Prague

Cheap St. Louis to Prague (STL to PRG) flight deals and tips

Best Price Found

Fastest flight time

Direct flights

Frequently asked questions about flying from St. Louis to Prague

Best airlines flying from St. Louis to Prague

Compare and see reviews for airlines that fly from St. Louis to Prague with momondo

Traveling to a place near Prague?

Why use momondo?

An easier way to manage your Prague trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

Find better results for your trip to the Czech Republic

Fly your favorite airline to Prague

Airlines are sorted and displayed according to clicks in the past 7 days on momondo

Cabin classes currently available on flights to Prague

List of cabin classes available on flights landing in Prague. Availability may vary depending on flight origin and airline.

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Popular flights according to clicks in the last 7 days on momondo

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