What is the most punctual flight time for St. Louis to Panama flights?

Generally, flights departing at night tend to experience fewer delays. Flights at night have, in the past, seen delays more frequently in comparison.

What day of the week experiences the fewest flight delays on this route?

Thursday is statistically the day of the week which experiences the fewest number of delays on this flight route. Thursday has historically seen more delays on average compared to the rest of the week.

What is the cheapest airline that flies from Lambert-St Louis to Panama?

United Airlines and Delta are the most popular carriers operating from Lambert-St Louis to Panama

What airlines fly to Panama?

United Airlines, Delta and American Airlines are the top three most popular airlines that fly to Panama from St. Louis according to our data. United Airlines is the first choice among our users, with 48% of people opting to fly with this airline when traveling to Panama. Keep in mind that there are 3 different airlines that fly to Panama on a routine basis, so you have a few additional options to choose from.

How often are flights from St. Louis to Panama delayed?

Historically, on average around 0% of flights between St. Louis and Panama have experienced a delay on any given week. The average delay length over the past 12 months has been 0 minutes.

When did momondo last update prices for flights from Lambert-St Louis Airport to Panama?

Prices for flights from Lambert-St Louis Airport to Panama are refreshed on a daily basis.

How many operators does momondo search for flights from Lambert-St Louis Airport to Panama?

The number of operators available for flights from Lambert-St Louis Airport to Panama is 3 as of July 2026.

How old do you have to be to fly from Lambert-St Louis Airport to Panama?

Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Lambert-St Louis Airport to Panama.

What documentation or ID do you need to fly to Panama?

The required travel and health documents for your Panama trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Panama. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

$260 Cheap Flights from St. Louis to Panama in 2026

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from St. Louis to Panama

Round-trip

One-way

Last minute

Cheap round-trip flights

Enter your travel dates to find the best prices.

6:00 am - 12:55 pm

STL

PTY

6h 55m

1 stop

2:20 pm - 11:58 pm

PTY

STL

9h 38m

1 stop

$585Delta

Mon, Aug 10 - Mon, Aug 17

6:14 am - 6:37 pm

STL

PTY

12h 23m

1 stop

3:30 pm - 3:38 pm

PTY

STL

24h 08m

2 stops

$589United Airlines

Mon, Aug 10 - Mon, Aug 17

10:44 am - 12:55 pm

STL

PTY

26h 11m

1 stop

2:20 pm - 8:08 am

PTY

STL

17h 48m

1 stop

$594Delta

Sun, Aug 9 - Tue, Aug 18

12:28 pm - 4:04 am

STL

PTY

15h 36m

1 stop

3:30 pm - 10:10 am

PTY

STL

18h 40m

1 stop

$595United Airlines

Thu, Aug 13 - Mon, Aug 17

8:50 am - 4:04 am

STL

PTY

19h 14m

2 stops

3:30 pm - 10:10 am

PTY

STL

18h 40m

1 stop

$599United Airlines

Wed, Aug 12 - Mon, Aug 17

9:30 am - 7:31 pm

STL

PTY

10h 01m

1 stop

7:55 am - 8:48 am

PTY

STL

24h 53m

3 stops

$602United Airlines

Fri, Oct 23 - Wed, Oct 28

6:30 pm - 6:37 pm

STL

PTY

24h 07m

1 stop

10:55 pm - 11:38 pm

PTY

STL

24h 43m

1 stop

$605United Airlines

Sun, Aug 2 - Mon, Aug 10

4:50 pm - 4:04 am

STL

PTY

11h 14m

1 stop

10:55 pm - 3:38 pm

PTY

STL

16h 43m

2 stops

$606United Airlines

Fri, Aug 14 - Tue, Aug 18

5:00 am - 12:39 pm

STL

PTY

7h 39m

1 stop

1:39 pm - 10:40 pm

PTY

STL

9h 01m

1 stop

$607American Airlines

Tue, Aug 11 - Sun, Aug 16

5:13 pm - 12:16 pm

STL

PTY

19h 03m

2 stops

1:16 pm - 10:20 am

PTY

STL

21h 04m

2 stops

$611American Airlines

Thu, Sep 17 - Sun, Sep 20

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Delta flights from St. Louis to Panama

Our best Delta deals on St. Louis to Panama flight tickets

Delta

Aug 10

STL6:00 amLambert-St Louis

6h 55m

1 stop

PTY12:55 pmPanama City Tocumen Intl

Aug 17

PTY2:20 pmPanama City Tocumen Intl

9h 38m

1 stop

STL11:58 pmLambert-St Louis

$585

Delta

Aug 9

STL10:44 amLambert-St Louis

26h 11m

1 stop

PTY12:55 pmPanama City Tocumen Intl

Aug 18

PTY2:20 pmPanama City Tocumen Intl

17h 48m

1 stop

STL8:08 amLambert-St Louis

$594

United Airlines flights from St. Louis to Panama

Our best United Airlines deals on St. Louis to Panama flight tickets

United Airlines

Aug 10

STL6:14 amLambert-St Louis

12h 23m

1 stop

PTY6:37 pmPanama City Tocumen Intl

Aug 17

PTY3:30 pmPanama City Tocumen Intl

24h 08m

2 stops

STL3:38 pmLambert-St Louis

$589

United Airlines

Aug 13

STL12:28 pmLambert-St Louis

15h 36m

1 stop

PTY4:04 amPanama City Tocumen Intl

Aug 17

PTY3:30 pmPanama City Tocumen Intl

18h 40m

1 stop

STL10:10 amLambert-St Louis

$595

United Airlines

Aug 12

STL8:50 amLambert-St Louis

19h 14m

2 stops

PTY4:04 amPanama City Tocumen Intl

Aug 17

PTY3:30 pmPanama City Tocumen Intl

18h 40m

1 stop

STL10:10 amLambert-St Louis

$599

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Quickest round-trip

St. LouisPanama City

STL - PTY

STLPTY

Lambert-St Louis

Mon 8/10

6:00 am-12:55 pm

1 stop6h 55m

Panama City Tocumen Intl

Mon 8/17

2:20 pm-11:58 pm

1 stop9h 38m

$585

St. LouisPanama City

STL - PTY

STLPTY

Lambert-St Louis

Mon 8/10

6:14 am-6:37 pm

1 stop12h 23m

Panama City Tocumen Intl

Mon 8/17

3:30 pm-3:38 pm

2 stops24h 08m

$589

St. LouisPanama City

STL - PTY

STLPTY

Lambert-St Louis

Sun 8/9

10:44 am-12:55 pm

1 stop26h 11m

Panama City Tocumen Intl

Tue 8/18

2:20 pm-8:08 am

1 stop17h 48m

$594

St. LouisPanama City

STL - PTY

STLPTY

Lambert-St Louis

Thu 8/13

12:28 pm-4:04 am

1 stop15h 36m

Panama City Tocumen Intl

Mon 8/17

3:30 pm-10:10 am

1 stop18h 40m

$595

St. LouisPanama City

STL - PTY

STLPTY

Lambert-St Louis

Wed 8/12

8:50 am-4:04 am

2 stops19h 14m

Panama City Tocumen Intl

Mon 8/17

3:30 pm-10:10 am

1 stop18h 40m

$599

St. LouisPanama City

STL - PTY

STLPTY

Lambert-St Louis

Fri 10/23

9:30 am-7:31 pm

1 stop10h 01m

Panama City Tocumen Intl

Wed 10/28

7:55 am-8:48 am

3 stops24h 53m

$602

St. LouisPanama City

STL - PTY

STLPTY

Lambert-St Louis

Sun 8/2

6:30 pm-6:37 pm

1 stop24h 07m

Panama City Tocumen Intl

Mon 8/10

10:55 pm-11:38 pm

1 stop24h 43m

$605

St. LouisPanama City

STL - PTY

STLPTY

Lambert-St Louis

Fri 8/14

4:50 pm-4:04 am

1 stop11h 14m

Panama City Tocumen Intl

Tue 8/18

10:55 pm-3:38 pm

2 stops16h 43m

$606

St. LouisPanama City

STL - PTY

STLPTY

Lambert-St Louis

Tue 8/11

5:00 am-12:39 pm

1 stop7h 39m

Panama City Tocumen Intl

Sun 8/16

1:39 pm-10:40 pm

1 stop9h 01m

$607

St. LouisPanama City

STL - PTY

STLPTY

Lambert-St Louis

Thu 9/17

5:13 pm-12:16 pm

2 stops19h 03m

Panama City Tocumen Intl

Sun 9/20

1:16 pm-10:20 am

2 stops21h 04m

$611

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from St. Louis to Panama

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Delays

What is the cheapest month to fly to Panama?

The month of February is, on average, the cheapest month to fly to Panama from St. Louis, with most prices found around $174. If you don’t want to visit Panama in February, then you should wait until January to fly from St. Louis, when ticket prices are also cheap, with an average price of $362.

Can stopping save me money on St. Louis to Panama flights?

You could potentially save up to 5% on your flight if you consider stops on a St. Louis to Panama flight.

Cheap St. Louis to Panama flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from St. Louis to Panama

Fastest flight time	6h 56m
Direct flights	None

The fastest flight from St. Louis to Panama takes 6h 56m

There are no direct flights from St. Louis to Panama. There are no popular flight routes from St. Louis to Panama.

Search flight deals

Frequently asked questions about flying from St. Louis to Panama

When did momondo last update prices for flights from Lambert-St Louis Airport to Panama?
Prices for flights from Lambert-St Louis Airport to Panama are refreshed on a daily basis.
How many operators does momondo search for flights from Lambert-St Louis Airport to Panama?
The number of operators available for flights from Lambert-St Louis Airport to Panama is 3 as of July 2026.
How old do you have to be to fly from Lambert-St Louis Airport to Panama?
Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Lambert-St Louis Airport to Panama.
What documentation or ID do you need to fly to Panama?
The required travel and health documents for your Panama trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Panama. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from St. Louis to Panama

Compare and see reviews for airlines that fly from St. Louis to Panama with momondo

Airline	Rating	Free Cancellation	Price
United Airlines	PriceFrom $393	Free Cancellation	Rating 7.4 9,944 reviews	Search United Airlines flights
American Airlines	PriceFrom $393	Free Cancellation	Rating 7.1 11,782 reviews	Search American Airlines flights
Delta	PriceFrom $478	Free Cancellation	Rating 7.8 8,450 reviews	Search Delta flights

Why use momondo?

Why should I use momondo to find a flight deal from St. Louis to Panama?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from St. Louis to Panama. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from St. Louis to Panama with flexible booking policies on momondo?

Yes. All flights to Panama from St. Louis on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from St. Louis to Panama?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Panama from St. Louis.

I’m not ready to book a flight from St. Louis to Panama right now. Can momondo alert me if prices change?

If you are not ready to book a flight from St. Louis to Panama now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Panama and let you know when they change.

An easier way to manage your Panama trip

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Flights to Panama Cityfrom $361

Flights to Bocas del Torofrom $863

Flights to Davidfrom $420

Flights to Changuinola

Cheap flights from St. Louis to Panama from $260

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from St. Louis to Panama departing on 8/10. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.

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Delta flights from St. Louis to Panama

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How to get the cheapest flight ticket from St. Louis to Panama

What is the cheapest month to fly to Panama?

Can stopping save me money on St. Louis to Panama flights?

What is the cheapest airline that flies from Lambert-St Louis to Panama?

What airlines fly to Panama?

How often are flights from St. Louis to Panama delayed?

What is the most punctual flight time for St. Louis to Panama flights?

What day of the week experiences the fewest flight delays on this route?

Cheap St. Louis to Panama flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from St. Louis to Panama

Fastest flight time

Direct flights

Frequently asked questions about flying from St. Louis to Panama

Best airlines flying from St. Louis to Panama

Compare and see reviews for airlines that fly from St. Louis to Panama with momondo

Why use momondo?

An easier way to manage your Panama trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

Find better results for your trip to Panama

Popular cities in Panama

Popular flights according to clicks in the last 7 days on momondo

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According to popular flight searches on momondo this year

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According to popular flight searches on momondo this year

Fly your favorite airline to Panama

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Cabin classes currently available on flights to Panama

List of cabin classes available on flights landing in Panama. Availability may vary depending on flight origin and airline.

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According to popular flight searches on momondo this year