How often are flights from St. Louis to Panama delayed?

Historically, on average around 0% of flights between St. Louis and Panama have experienced a delay on any given week. The average delay length over the past 12 months has been 0 minutes.

What is the cheapest airline that flies from Lambert-St Louis to Panama?

United Airlines is the most popular carrier operating from Lambert-St Louis to Panama

What airlines fly to Panama?

United Airlines, Delta and American Airlines are the top three most popular airlines that fly to Panama from St. Louis according to our data. United Airlines is the first choice among our users, with 43% of people opting to fly with this airline when traveling to Panama. Keep in mind that there are 4 different airlines that fly to Panama on a routine basis, so you have a few additional options to choose from.

What day of the week experiences the fewest flight delays on this route?

Thursday is statistically the day of the week which experiences the fewest number of delays on this flight route. Thursday has historically seen more delays on average compared to the rest of the week.

What is the most punctual flight time for St. Louis to Panama flights?

Generally, flights departing at night tend to experience fewer delays. Flights at night have, in the past, seen delays more frequently in comparison.

When did momondo last update prices for flights from Lambert-St Louis Airport to Panama?

Prices for flights from Lambert-St Louis Airport to Panama are refreshed on a daily basis.

How many operators does momondo search for flights from Lambert-St Louis Airport to Panama?

The number of operators available for flights from Lambert-St Louis Airport to Panama is 4 as of August 2026.

How old do you have to be to fly from Lambert-St Louis Airport to Panama?

Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Lambert-St Louis Airport to Panama.

What documentation or ID do you need to fly to Panama?

The required travel and health documents for your Panama trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Panama. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

$297 Cheap Flights from St. Louis to Panama in 2026

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from St. Louis to Panama

Round-trip

One-way

Last minute

Cheap round-trip flights

Enter your travel dates to find the best prices.

5:00 am - 12:16 pmSTL Lambert-St Louis-PTY Panama City Tocumen Intl

7h 16m1 stop Miami

2:02 pm - 9:59 pmPTY Panama City Tocumen Intl-STL Lambert-St Louis

7h 57m1 stop Miami

$665American Airlines

Fri, Oct 2 - Fri, Oct 9

5:00 am - 12:16 pmSTL Lambert-St Louis-PTY Panama City Tocumen Intl

7h 16m1 stop Miami

1:16 pm - 11:59 pmPTY Panama City Tocumen Intl-STL Lambert-St Louis

10h 43m1 stop Miami

$665American Airlines

Fri, Sep 18 - Fri, Sep 25

6:15 am - 6:37 pmSTL Lambert-St Louis-PTY Panama City Tocumen Intl

12h 22m1 stop Houston George Bush Intcntl

3:30 pm - 12:13 pmPTY Panama City Tocumen Intl-STL Lambert-St Louis

20h 43m2 stops Houston George Bush Intcntl Chicago O'Hare Intl

$665United Airlines

Thu, Oct 1 - Thu, Oct 8

6:15 am - 6:37 pmSTL Lambert-St Louis-PTY Panama City Tocumen Intl

12h 22m1 stop Houston George Bush Intcntl

7:55 am - 10:26 pmPTY Panama City Tocumen Intl-STL Lambert-St Louis

14h 31m1 stop Houston George Bush Intcntl

$665United Airlines

Thu, Oct 15 - Mon, Oct 26

7:20 pm - 12:59 pmSTL Lambert-St Louis-PTY Panama City Tocumen Intl

17h 39m1 stop Atlanta Hartsfield-Jackson

2:24 pm - 11:54 pmPTY Panama City Tocumen Intl-STL Lambert-St Louis

9h 30m1 stop Atlanta Hartsfield-Jackson

$665Delta

Sun, Oct 11 - Tue, Oct 27

7:20 pm - 12:59 pmSTL Lambert-St Louis-PTY Panama City Tocumen Intl

17h 39m1 stop Atlanta Hartsfield-Jackson

2:24 pm - 11:54 pmPTY Panama City Tocumen Intl-STL Lambert-St Louis

9h 30m1 stop Atlanta Hartsfield-Jackson

$665Delta

Mon, Oct 12 - Wed, Oct 21

6:30 am - 8:02 pmSTL Lambert-St Louis-PTY Panama City Tocumen Intl

12h 32m1 stop Newark

4:41 pm - 10:06 pmPTY Panama City Tocumen Intl-STL Lambert-St Louis

30h 25m1 stop Houston George Bush Intcntl

$759Copa Airlines

Fri, Jan 8 - Sun, Jan 17

6:15 am - 7:38 pmSTL Lambert-St Louis-PTY Panama City Tocumen Intl

12h 23m1 stop Houston George Bush Intcntl

4:41 pm - 10:06 pmPTY Panama City Tocumen Intl-STL Lambert-St Louis

30h 25m1 stop Houston George Bush Intcntl

$759Copa Airlines

Fri, Jan 8 - Sun, Jan 17

7:00 am - 12:16 pmSTL Lambert-St Louis-PTY Panama City Tocumen Intl

29h 16m2 stops Dallas/Fort Worth Miami

1:16 pm - 9:49 pmPTY Panama City Tocumen Intl-STL Lambert-St Louis

8h 33m1 stop Miami

$776GOL

Thu, Sep 17 - Tue, Sep 22

5:13 pm - 12:16 pmSTL Lambert-St Louis-PTY Panama City Tocumen Intl

19h 03m2 stops Washington, D.C. Reagan-National Miami

1:16 pm - 12:27 amPTY Panama City Tocumen Intl-STL Lambert-St Louis

11h 11m2 stops Miami Chicago O'Hare Intl

$776GOL

Thu, Sep 17 - Tue, Sep 22

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American Airlines flights from St. Louis to Panama

Our best American Airlines deals on St. Louis to Panama flight tickets

American Airlines

Sep 18

STL5:00 amLambert-St Louis

7h 16m

1 stop

PTY12:16 pmPanama City Tocumen Intl

Sep 21

PTY1:16 pmPanama City Tocumen Intl

10h 43m

1 stop

STL11:59 pmLambert-St Louis

$687

American Airlines

Oct 16

STL5:27 pmLambert-St Louis

19h 35m

2 stops

PTY1:02 pmPanama City Tocumen Intl

Oct 30

PTY2:02 pmPanama City Tocumen Intl

7h 57m

1 stop

STL9:59 pmLambert-St Louis

$691

American Airlines

Sep 17

STL2:11 pmLambert-St Louis

22h 05m

1 stop

PTY12:16 pmPanama City Tocumen Intl

Sep 21

PTY1:16 pmPanama City Tocumen Intl

10h 43m

1 stop

STL11:59 pmLambert-St Louis

$701

United Airlines flights from St. Louis to Panama

Our best United Airlines deals on St. Louis to Panama flight tickets

United Airlines

Oct 12

STL7:30 amLambert-St Louis

12h 01m

1 stop

PTY7:31 pmPanama City Tocumen Intl

Oct 21

PTY3:30 pmPanama City Tocumen Intl

20h 43m

2 stops

STL12:13 pmLambert-St Louis

$665

United Airlines

Oct 13

STL5:36 pmLambert-St Louis

20h 38m

2 stops

PTY2:14 pmPanama City Tocumen Intl

Oct 26

PTY3:41 pmPanama City Tocumen Intl

18h 51m

2 stops

STL10:32 amLambert-St Louis

$669

United Airlines

Nov 15

STL2:55 pmLambert-St Louis

27h 43m

1 stop

PTY7:38 pmPanama City Tocumen Intl

Nov 19

PTY8:55 amPanama City Tocumen Intl

14h 30m

1 stop

STL10:25 pmLambert-St Louis

$676

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Quickest round-trip

St. LouisPanama City

STL Lambert-St Louis - PTY Panama City Tocumen Intl

STLPTY

Lambert-St Louis

Fri 10/2

5:00 am-12:16 pm

1 stop7h 16m

Panama City Tocumen Intl

Fri 10/9

2:02 pm-9:59 pm

1 stop7h 57m

$665

St. LouisPanama City

STL Lambert-St Louis - PTY Panama City Tocumen Intl

STLPTY

Lambert-St Louis

Fri 9/18

5:00 am-12:16 pm

1 stop7h 16m

Panama City Tocumen Intl

Fri 9/25

1:16 pm-11:59 pm

1 stop10h 43m

$665

St. LouisPanama City

STL Lambert-St Louis - PTY Panama City Tocumen Intl

STLPTY

Lambert-St Louis

Thu 10/1

6:15 am-6:37 pm

1 stop12h 22m

Panama City Tocumen Intl

Thu 10/8

3:30 pm-12:13 pm

2 stops20h 43m

$665

St. LouisPanama City

STL Lambert-St Louis - PTY Panama City Tocumen Intl

STLPTY

Lambert-St Louis

Thu 10/15

6:15 am-6:37 pm

1 stop12h 22m

Panama City Tocumen Intl

Mon 10/26

7:55 am-10:26 pm

1 stop14h 31m

$665

St. LouisPanama City

STL Lambert-St Louis - PTY Panama City Tocumen Intl

STLPTY

Lambert-St Louis

Sun 10/11

7:20 pm-12:59 pm

1 stop17h 39m

Panama City Tocumen Intl

Tue 10/27

2:24 pm-11:54 pm

1 stop9h 30m

$665

St. LouisPanama City

STL Lambert-St Louis - PTY Panama City Tocumen Intl

STLPTY

Lambert-St Louis

Mon 10/12

7:20 pm-12:59 pm

1 stop17h 39m

Panama City Tocumen Intl

Wed 10/21

2:24 pm-11:54 pm

1 stop9h 30m

$665

St. LouisPanama City

STL Lambert-St Louis - PTY Panama City Tocumen Intl

STLPTY

Lambert-St Louis

Fri 1/8

6:30 am-8:02 pm

1 stop12h 32m

Panama City Tocumen Intl

Sun 1/17

4:41 pm-10:06 pm

1 stop30h 25m

$759

St. LouisPanama City

STL Lambert-St Louis - PTY Panama City Tocumen Intl

STLPTY

Lambert-St Louis

Fri 1/8

6:15 am-7:38 pm

1 stop12h 23m

Panama City Tocumen Intl

Sun 1/17

4:41 pm-10:06 pm

1 stop30h 25m

$759

St. LouisPanama City

STL Lambert-St Louis - PTY Panama City Tocumen Intl

STLPTY

Lambert-St Louis

Thu 9/17

7:00 am-12:16 pm

2 stops29h 16m

Panama City Tocumen Intl

Tue 9/22

1:16 pm-9:49 pm

1 stop8h 33m

$776

St. LouisPanama City

STL Lambert-St Louis - PTY Panama City Tocumen Intl

STLPTY

Lambert-St Louis

Thu 9/17

5:13 pm-12:16 pm

2 stops19h 03m

Panama City Tocumen Intl

Tue 9/22

1:16 pm-12:27 am

2 stops11h 11m

$776

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 13 resultsSorted by cheapest first

How to get the cheapest flight ticket from St. Louis to Panama

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Delays

What is the cheapest month to fly to Panama?

The month of April is, on average, the cheapest month to fly to Panama from St. Louis, with most prices found around $495. If you don’t want to visit Panama in April, then you should wait until November to fly from St. Louis, when ticket prices are also cheap, with an average price of $510.

Can stopping save me money on St. Louis to Panama flights?

You could potentially save up to 22% on your flight if you consider stops on a St. Louis to Panama flight.

Cheap St. Louis to Panama flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from St. Louis to Panama

Best Price Found	$297
Fastest flight time	6h 55m
Direct flights	None

The best one-way flight to Panama from St. Louis in the past 72 hours is $297. The best round-trip flight deal from St. Louis to Panama found on momondo in the last 72 hours is $665.

The fastest flight from St. Louis to Panama takes 6h 55m

There are no direct flights from St. Louis to Panama. There are no popular flight routes from St. Louis to Panama.

Search flight deals

Frequently asked questions about flying from St. Louis to Panama

When did momondo last update prices for flights from Lambert-St Louis Airport to Panama?
Prices for flights from Lambert-St Louis Airport to Panama are refreshed on a daily basis.
How many operators does momondo search for flights from Lambert-St Louis Airport to Panama?
The number of operators available for flights from Lambert-St Louis Airport to Panama is 4 as of August 2026.
How old do you have to be to fly from Lambert-St Louis Airport to Panama?
Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Lambert-St Louis Airport to Panama.
What documentation or ID do you need to fly to Panama?
The required travel and health documents for your Panama trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Panama. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from St. Louis to Panama

Compare and see reviews for airlines that fly from St. Louis to Panama with momondo

Airline	Rating	Free Cancellation	Price
American Airlines	PriceFrom $393	Free Cancellation	Rating 7.1 11,990 reviews	Search American Airlines flights
United Airlines	PriceFrom $393	Free Cancellation	Rating 7.4 10,112 reviews	Search United Airlines flights
Copa Airlines	PriceFrom $446	Free Cancellation	Rating 7.6 1,553 reviews	Search Copa Airlines flights
Delta	PriceFrom $478	Free Cancellation	Rating 7.8 8,517 reviews	Search Delta flights

Why use momondo?

Why should I use momondo to find a flight deal from St. Louis to Panama?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from St. Louis to Panama. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from St. Louis to Panama with flexible booking policies on momondo?

Yes. All flights to Panama from St. Louis on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from St. Louis to Panama?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Panama from St. Louis.

I’m not ready to book a flight from St. Louis to Panama right now. Can momondo alert me if prices change?

If you are not ready to book a flight from St. Louis to Panama now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Panama and let you know when they change.

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Flights to Panama Cityfrom $400

Flights to Bocas del Torofrom $1,130

Flights to Davidfrom $508

Flights to Changuinola

Cheap flights from St. Louis to Panama from $297

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from St. Louis to Panama departing on 10/5. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.

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American Airlines flights from St. Louis to Panama

Our best American Airlines deals on St. Louis to Panama flight tickets

United Airlines flights from St. Louis to Panama

Our best United Airlines deals on St. Louis to Panama flight tickets

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How to get the cheapest flight ticket from St. Louis to Panama

What is the cheapest month to fly to Panama?

Can stopping save me money on St. Louis to Panama flights?

What is the cheapest airline that flies from Lambert-St Louis to Panama?

What airlines fly to Panama?

How often are flights from St. Louis to Panama delayed?

What is the most punctual flight time for St. Louis to Panama flights?

What day of the week experiences the fewest flight delays on this route?

Cheap St. Louis to Panama flight deals and tips

Best Price Found

Fastest flight time

Direct flights

Frequently asked questions about flying from St. Louis to Panama

Best airlines flying from St. Louis to Panama

Compare and see reviews for airlines that fly from St. Louis to Panama with momondo

Why use momondo?

An easier way to manage your Panama trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

Find better results for your trip to Panama

Popular cities in Panama

Popular flights according to clicks in the last 7 days on momondo

St. Louis flight routes

According to popular flight searches on momondo this year

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According to popular flight searches on momondo this year

Fly your favorite airline to Panama

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Cabin classes currently available on flights to Panama

List of cabin classes available on flights landing in Panama. Availability may vary depending on flight origin and airline.

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Explore popular destinations other users love

According to popular flight searches on momondo this year