Cheap flights from Boston to Panama City from $306

In general, May is the cheapest month to fly from Boston to Panama City. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $588. If you’re not able to fly to Panama City in May, then October is your next best option. Flight prices from Boston to Panama City during October average around $606.

Our data shows that Tuesday is the least expensive day to fly to Panama City. Tickets to fly out on this day can be as low as $556. If your travel schedule is flexible, try to avoid departing on a Friday because tickets tend to average around $649. These prices are subject to change though, so be sure to set up a Price Alert for flights to Panama City.

Our most recent data shows that the best time of day to fly to Panama City is in the afternoon. Flights from Boston to Panama City during this time can be as low as $521. Try not to purchase tickets in the morning because they tend to be around $635. Of course, these prices can vary depending on the time of year and what airport you fly to.

Fly from Boston Logan Intl to Panama City Tocumen Intl for the best Boston Logan Intl - Panama City Tocumen Intl flight prices

You are more likely to see cheaper flights to Panama City from Boston when booking weeks ahead of your departure date. In general, you can expect to find flights to Panama City for around $659 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Panama City from Boston for as low as $461 on momondo.

There are 3 cabin classes available to choose from on Boston to Panama City flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

You could potentially save up to 52% on your flight if you consider stops on a Boston to Panama City flight.

Aeromexico and Avianca are the most popular carriers operating from Boston Logan Intl to Panama City Tocumen Intl

Copa Airlines, United Airlines and Delta are the top three most popular airlines that fly to Panama City from Boston according to our data. Copa Airlines is the first choice among our users, with 89% of people opting to fly with this airline when traveling to Panama City. Keep in mind that there are 5 different airlines that fly to Panama City on a routine basis, so you have a few additional options to choose from.

Historically, on average around 14% of flights between Boston and Panama City have experienced a delay on any given week. The average delay length over the past 12 months has been 109 minutes.

Generally, flights departing in the morning tend to experience fewer delays. Flights at night have, in the past, seen delays more frequently in comparison.

Friday is statistically the day of the week which experiences the fewest number of delays on this flight route. Sunday has historically seen more delays on average compared to the rest of the week.

According to our data, Copa Airlines have had the least number of delays on this route over the last 12 months; with about 14% of their flights experiencing any sort of delay.

Newark (EWR) was the most common stop: 80% of momondo users choosing 1-stop flights on this route connected there.

Flights via Atlanta (ATL) offer the lowest average round-trip price of $510.

Flights connecting via Atlanta (ATL) have the shortest average one-way travel time: 8h 19m.

Newark (EWR) has the shortest average layover time for this route: 2h 00m.

The number of flights available between Boston and Panama City is 2 per day as of June 2026. The most frequent departure time is 8:00AM, with 100% of daily flights leaving at noon.

As of June 2026, there are 19 flights per week flying from Boston to Panama City. The most common day of the week flights depart is Mon, with 16% of flights taking off on this day.