How many flights depart from South Carolina to Des Moines on average per week?

As of July 2025, there are 13 flights per week flying from South Carolina to Des Moines. The most common day of the week flights depart is Mon, with 15% of flights taking off on this day.

How long does it take to fly to Des Moines?

If you’re flying from a popular airport in South Carolina, such as Greenville or Columbia, and flying into Des Moines, then you can expect flight times to average 4h 09m and 4h 22m, respectively.

What airlines fly to Des Moines?

American Airlines, Delta and United Airlines are the top three most popular airlines that fly to Des Moines from South Carolina according to our data. American Airlines is the first choice among our users, with 48% of people opting to fly with this airline when traveling to Des Moines. Keep in mind that there are 3 different airlines that fly to Des Moines on a routine basis, so you have a few additional options to choose from.

What is the cheapest airline that flies from South Carolina to Des Moines?

American Airlines, Southwest, and Allegiant Air are the most popular carriers operating from South Carolina to Des Moines

When did momondo last update prices for flights from South Carolina to Des Moines Airport?

Prices for flights from South Carolina to Des Moines Airport refresh daily.

How many operators does momondo search for flights from South Carolina to Des Moines Airport?

There are 3 operators available for flights from South Carolina to Des Moines Airport as of July 2025.

How old do you have to be to fly from South Carolina to Des Moines Airport?

The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from South Carolina to Des Moines Airport.

What documentation or ID do you need to fly to Des Moines Airport?

The travel and health documents you'll need for your trip to Des Moines Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Des Moines Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

$80 Cheap Flights from South Carolina to Des Moines in 2025

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Find the cheapest flights from South Carolina to Des Moines

Round-trip

One-way

Last minute

Direct

Cheap round-trip flights

6:35 am - 1:05 pmGSP-DSM

7h 30m1 stop

4:09 pm - 10:30 pmDSM-GSP

5h 21m1 stop

$159American Airlines

Find Deal

mié., sep. 10 - lun., sep. 15

6:20 am - 10:45 amSAV-DSM

5h 25m1 stop

5:00 am - 11:29 amDSM-SAV

5h 29m1 stop

$163American Airlines

Find Deal

mar., oct. 21 - mar., oct. 28

1:50 pm - 9:50 pmSAV-DSM

9h 00m2 stops

10:15 am - 8:05 pmDSM-SAV

8h 50m2 stops

$169Southwest

Find Deal

mar., oct. 21 - mar., oct. 28

2:35 pm - 10:50 pmCHS-DSM

9h 15m2 stops

7:00 am - 3:35 pmDSM-CHS

7h 35m1 stop

$194Southwest

Find Deal

jue., sep. 18 - lun., sep. 22

9:52 pm - 1:32 pmCLT-DSM

16h 40m2 stops

5:49 pm - 9:22 amDSM-CLT

14h 33m2 stops

$209

Find Deal

jue., sep. 4 - dom., sep. 7

9:10 am - 2:40 pmCLT-DSM

6h 30m1 stop

5:49 pm - 9:22 amDSM-CLT

14h 33m2 stops

$214

Find Deal

vie., sep. 5 - dom., sep. 7

5:30 am - 10:40 amGSP-DSM

6h 10m1 stop

6:30 pm - 11:34 pmDSM-GSP

4h 04m1 stop

$217Delta

Find Deal

jue., sep. 11 - mié., sep. 17

5:30 am - 10:38 amGSP-DSM

6h 08m1 stop

7:15 am - 2:41 pmDSM-GSP

6h 26m1 stop

$234Delta

Find Deal

lun., sep. 8 - jue., sep. 18

6:08 am - 2:10 pmGSP-DSM

9h 02m2 stops

3:25 pm - 9:01 pmDSM-GSP

4h 36m1 stop

$266United Airlines

Find Deal

mar., sep. 9 - sáb., sep. 13

6:08 am - 2:10 pmGSP-DSM

9h 02m2 stops

11:35 am - 10:58 pmDSM-GSP

10h 23m2 stops

$271United Airlines

Find Deal

mar., sep. 9 - sáb., sep. 13

United Airlines flights from South Carolina to Des Moines

Our best United Airlines deals on South Carolina to Des Moines flight tickets

United Airlines

Sep 9

GSP6:08 amGreenville

9h 02m

2 stops

DSM2:10 pmDes Moines

Sep 13

DSM3:25 pmDes Moines

4h 36m

1 stop

GSP9:01 pmGreenville

$266

Find similar

United Airlines

Sep 9

GSP6:08 amGreenville

9h 02m

2 stops

DSM2:10 pmDes Moines

Sep 13

DSM11:35 amDes Moines

10h 23m

2 stops

GSP10:58 pmGreenville

$271

Find similar

United Airlines

Dec 3

CAE5:24 pmColumbia Metropolitan

4h 58m

1 stop

DSM9:22 pmDes Moines

Dec 14

DSM3:25 pmDes Moines

5h 40m

1 stop

CAE10:05 pmColumbia Metropolitan

$319

Find similar

Southwest flights from South Carolina to Des Moines

Our best Southwest deals on South Carolina to Des Moines flight tickets

Southwest

Oct 21

SAV1:50 pmSavannah/Hilton Head

9h 00m

2 stops

DSM9:50 pmDes Moines

Oct 28

DSM10:15 amDes Moines

8h 50m

2 stops

SAV8:05 pmSavannah/Hilton Head

$169

Find similar

Southwest

Sep 18

CHS2:35 pmCharleston

9h 15m

2 stops

DSM10:50 pmDes Moines

Sep 22

DSM7:00 amDes Moines

7h 35m

1 stop

CHS3:35 pmCharleston

$194

Find similar

Southwest

Sep 18

CHS2:35 pmCharleston

9h 15m

2 stops

DSM10:50 pmDes Moines

Sep 22

DSM7:00 amDes Moines

11h 00m

2 stops

CHS7:00 pmCharleston

$199

Find similar

How to get the cheapest flight ticket from South Carolina to Des Moines

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Other information

What is the cheapest month to fly to Des Moines?

If you’re not able to fly to Des Moines in May, then July is your next best option. Flight prices from South Carolina to Des Moines during July average around $335.

What is the cheapest day to depart on your flight to Des Moines?

The cheapest day to depart from South Carolina to Des Moines is on a Wednesday. Travelers who choose to depart for Des Moines on a Wednesday will often find tickets for as low as $321. Flights from South Carolina to Des Moines on a Saturday will generally be more expensive and average around $594. Keep in mind that these prices on both days could fluctuate depending on the season and the demand.

What is the cheapest time of day to depart on your flight to Des Moines?

According to our data, the cheapest time of day to fly to Des Moines is in the afternoon. momondo users have found flights departing from South Carolina to Des Moines in the afternoon for as low as $411. Keep in mind that these prices may fluctuate based on what airline you choose and the time of year you plan to travel. Try not to purchase tickets at noon because they tend to be around $485. Of course, these prices can vary depending on the time of year and what airport you fly to.

Cheap South Carolina to Des Moines flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from South Carolina to Des Moines

Best Price Found	$80
Fastest flight time	2h 18m
Direct flights	Every day
Airports in Des Moines	1 airport

The best one-way flight to Des Moines from South Carolina in the past 72 hours is $80. The best round-trip flight deal from South Carolina to Des Moines found on momondo in the last 72 hours is $159.

The fastest flight from South Carolina to Des Moines takes 2h 18m

Direct flights go from South Carolina to Des Moines every day.

There is 1 airport near Des Moines: Des Moines (DSM)

Search flight deals

When did momondo last update prices for flights from South Carolina to Des Moines Airport?
Prices for flights from South Carolina to Des Moines Airport refresh daily.
How many operators does momondo search for flights from South Carolina to Des Moines Airport?
There are 3 operators available for flights from South Carolina to Des Moines Airport as of July 2025.
How old do you have to be to fly from South Carolina to Des Moines Airport?
The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from South Carolina to Des Moines Airport.
What documentation or ID do you need to fly to Des Moines Airport?
The travel and health documents you'll need for your trip to Des Moines Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Des Moines Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

Best airlines flying from South Carolina to Des Moines

Compare and see reviews for airlines that fly from South Carolina to Des Moines with momondo

Airline	Rating	Free Cancellation	Price
American Airlines	PriceFrom $216	Free Cancellation	Rating 7.2 10,000 reviews	Search American Airlines flights
Delta	PriceFrom $236	Free Cancellation	Rating 8.0 7,952 reviews	Search Delta flights
United Airlines	PriceFrom $336	Free Cancellation	Rating 7.4 8,846 reviews	Search United Airlines flights

West Des Moines

Ames

Ankeny

Clive

Altoona

Urbandale

Newton

Pella

Boone

Johnston

Osceola

Norwalk

Grinnell

Oskaloosa

Carlisle

Why use momondo?

Why should I use momondo to find a flight deal from South Carolina to Des Moines?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Des Moines from South Carolina.

Can I find flights from South Carolina to Des Moines with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for South Carolina to Des Moines flights to just show those with flexible booking policies.

How can momondo help me find flights from South Carolina to Des Moines?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from South Carolina to Des Moines.

I’m not ready to book a flight from South Carolina to Des Moines right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of South Carolina to Des Moines flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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Cheap flights from South Carolina to Des Moines from $80

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from South Carolina to Des Moines departing on 8/7. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.

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Big names and deals

Filter for what you want

Filter for what you want

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Trusted and free

Price Alerts

Price Alerts

Find the cheapest flights from South Carolina to Des Moines

Cheap round-trip flights

Cheap one-way flights

Cheap last minute flights

Cheap direct flights

United Airlines flights from South Carolina to Des Moines

Our best United Airlines deals on South Carolina to Des Moines flight tickets

Southwest flights from South Carolina to Des Moines

Our best Southwest deals on South Carolina to Des Moines flight tickets

See travel insights to Des Moines from

How to get the cheapest flight ticket from South Carolina to Des Moines

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Des Moines?

If you’re not able to fly to Des Moines in May, then July is your next best option. Flight prices from South Carolina to Des Moines during July average around $335.

What is the cheapest day to depart on your flight to Des Moines?

What is the cheapest time of day to depart on your flight to Des Moines?

What is the cheapest airline that flies from South Carolina to Des Moines?

American Airlines, Southwest, and Allegiant Air are the most popular carriers operating from South Carolina to Des Moines

What airlines fly to Des Moines?

How many flights depart from South Carolina to Des Moines on average per week?

As of July 2025, there are 13 flights per week flying from South Carolina to Des Moines. The most common day of the week flights depart is Mon, with 15% of flights taking off on this day.

How long does it take to fly to Des Moines?

If you’re flying from a popular airport in South Carolina, such as Greenville or Columbia, and flying into Des Moines, then you can expect flight times to average 4h 09m and 4h 22m, respectively.

Cheap South Carolina to Des Moines flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from South Carolina to Des Moines

Best Price Found

Fastest flight time

Direct flights

Airports in Des Moines

When did momondo last update prices for flights from South Carolina to Des Moines Airport?

How many operators does momondo search for flights from South Carolina to Des Moines Airport?

How old do you have to be to fly from South Carolina to Des Moines Airport?

What documentation or ID do you need to fly to Des Moines Airport?

Best airlines flying from South Carolina to Des Moines

Compare and see reviews for airlines that fly from South Carolina to Des Moines with momondo

Traveling to a place near Des Moines?

Why use momondo?

Why should I use momondo to find a flight deal from South Carolina to Des Moines?

Can I find flights from South Carolina to Des Moines with flexible booking policies on momondo?

How can momondo help me find flights from South Carolina to Des Moines?

I’m not ready to book a flight from South Carolina to Des Moines right now. Can momondo alert me if prices change?

An easier way to manage your Des Moines trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

Find better results for your trip to the United States

Airports servicing Iowa