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Cheap flights from Santo Domingo to Charleston from $251

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Santo Domingo to Charleston departing on 8/27. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Find the cheapest flights from Santo Domingo to Charleston

Cheap round-trip flights

Enter your travel dates to find the best prices.
Delta Logo
2:53 pm - 10:11 pm
SDQ
-
CHS
7h 18m
1 stop
Delta Logo
6:40 am - 1:27 pm
CHS
-
SDQ
6h 47m
1 stop
$472Delta
Fri, Sep 18 - Fri, Oct 2
American Airlines Logo
10:21 am - 11:43 pm
SDQ
-
CHS
13h 22m
1 stop
American Airlines Logo
6:20 pm - 3:17 pm
CHS
-
SDQ
20h 57m
1 stop
$476American Airlines
Fri, Sep 18 - Fri, Oct 2
American Airlines Logo
2:22 pm - 9:39 am
SDQ
-
CHS
19h 17m
2 stops
American Airlines Logo
6:15 am - 6:44 pm
CHS
-
SDQ
12h 29m
2 stops
$481American Airlines
Thu, Aug 13 - Mon, Aug 24
Delta Logo
2:53 pm - 10:11 pm
SDQ
-
CHS
7h 18m
1 stop
Delta Logo
6:00 am - 5:29 pm
CHS
-
SDQ
11h 29m
1 stop
$484Delta
Fri, Sep 18 - Fri, Oct 2
American Airlines Logo
10:27 am - 11:59 pm
SDQ
-
CHS
13h 32m
1 stop
American Airlines Logo
6:00 am - 12:35 pm
CHS
-
SDQ
6h 35m
1 stop
$491American Airlines
Wed, Oct 21 - Sun, Oct 25
Delta Logo
2:53 pm - 10:11 pm
SDQ
-
CHS
7h 18m
1 stop
Delta Logo
6:40 am - 1:27 pm
CHS
-
SDQ
6h 47m
1 stop
$495Delta
Fri, Sep 18 - Fri, Oct 2
American Airlines Logo
2:15 pm - 9:47 am
SDQ
-
CHS
19h 32m
2 stops
American Airlines Logo
6:00 am - 6:34 pm
CHS
-
SDQ
12h 34m
1 stop
$504American Airlines
Fri, Sep 18 - Fri, Oct 2
American Airlines Logo
2:22 pm - 9:39 am
SDQ
-
CHS
19h 17m
2 stops
American Airlines Logo
6:15 am - 6:44 pm
CHS
-
SDQ
12h 29m
2 stops
$505American Airlines
Thu, Aug 13 - Mon, Aug 24
American Airlines Logo
7:34 pm - 11:52 am
SDQ
-
CHS
16h 18m
2 stops
American Airlines Logo
6:00 am - 6:34 pm
CHS
-
SDQ
12h 34m
1 stop
$506American Airlines
Fri, Sep 18 - Fri, Oct 2
American Airlines Logo
2:00 pm - 11:54 pm
SDQ
-
CHS
9h 54m
1 stop
American Airlines Logo
6:00 am - 3:24 pm
CHS
-
SDQ
9h 24m
1 stop
$543American Airlines
Thu, Aug 13 - Mon, Aug 24

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JetBlue flights from Santo Domingo to Charleston

Our best JetBlue deals on Santo Domingo to Charleston flight tickets
JetBlue
Aug 13
SDQ5:01 amSanto Domingo Las Americas
11h 32m
1 stop
CHS4:33 pmCharleston
Aug 24
CHS5:59 pmCharleston
6h 00m
1 stop
SDQ11:59 pmSanto Domingo Las Americas
$576
JetBlue
Aug 16
SDQ5:01 amSanto Domingo Las Americas
11h 32m
1 stop
CHS4:33 pmCharleston
Aug 17
CHS5:59 pmCharleston
21h 24m
1 stop
SDQ3:23 pmSanto Domingo Las Americas
$821
JetBlue
Aug 16
SDQ7:40 pmSanto Domingo Las Americas
16h 34m
2 stops
CHS12:14 pmCharleston
Aug 17
CHS5:59 pmCharleston
6h 00m
1 stop
SDQ11:59 pmSanto Domingo Las Americas
$865

Delta flights from Santo Domingo to Charleston

Our best Delta deals on Santo Domingo to Charleston flight tickets
Delta
Sep 18
SDQ2:53 pmSanto Domingo Las Americas
7h 18m
1 stop
CHS10:11 pmCharleston
Oct 2
CHS6:40 amCharleston
6h 47m
1 stop
SDQ1:27 pmSanto Domingo Las Americas
$472
Delta
Sep 18
SDQ2:53 pmSanto Domingo Las Americas
7h 18m
1 stop
CHS10:11 pmCharleston
Oct 2
CHS6:00 amCharleston
11h 29m
1 stop
SDQ5:29 pmSanto Domingo Las Americas
$484
Delta
Sep 18
SDQ2:53 pmSanto Domingo Las Americas
7h 18m
1 stop
CHS10:11 pmCharleston
Oct 2
CHS6:40 amCharleston
6h 47m
1 stop
SDQ1:27 pmSanto Domingo Las Americas
$495

momondo Fare Finder

 
Customize your flight search to find flights from Santo Domingo to Charleston that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated July 27, 2026.
Use the filters below to find and compare flights from Santo Domingo to Charleston that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

Santo DomingoCharleston

SDQ - CHS

SDQCHS

Santo Domingo Las Americas

Fri 9/18

2:53 pm-10:11 pm

1 stop7h 18m

Charleston

Fri 10/2

6:40 am-1:27 pm

1 stop6h 47m

$472

Santo DomingoCharleston

SDQ - CHS

SDQCHS

Santo Domingo Las Americas

Fri 9/18

10:21 am-11:43 pm

1 stop13h 22m

Charleston

Fri 10/2

6:20 pm-3:17 pm

1 stop20h 57m

$476

Santo DomingoCharleston

SDQ - CHS

SDQCHS

Santo Domingo Las Americas

Thu 8/13

2:22 pm-9:39 am

2 stops19h 17m

Charleston

Mon 8/24

6:15 am-6:44 pm

2 stops12h 29m

$481

Santo DomingoCharleston

SDQ - CHS

SDQCHS

Santo Domingo Las Americas

Fri 9/18

2:53 pm-10:11 pm

1 stop7h 18m

Charleston

Fri 10/2

6:00 am-5:29 pm

1 stop11h 29m

$484

Santo DomingoCharleston

SDQ - CHS

SDQCHS

Santo Domingo Las Americas

Wed 10/21

10:27 am-11:59 pm

1 stop13h 32m

Charleston

Sun 10/25

6:00 am-12:35 pm

1 stop6h 35m

$491

Santo DomingoCharleston

SDQ - CHS

SDQCHS

Santo Domingo Las Americas

Fri 9/18

2:53 pm-10:11 pm

1 stop7h 18m

Charleston

Fri 10/2

6:40 am-1:27 pm

1 stop6h 47m

$495

Santo DomingoCharleston

SDQ - CHS

SDQCHS

Santo Domingo Las Americas

Fri 9/18

2:15 pm-9:47 am

2 stops19h 32m

Charleston

Fri 10/2

6:00 am-6:34 pm

1 stop12h 34m

$504

Santo DomingoCharleston

SDQ - CHS

SDQCHS

Santo Domingo Las Americas

Thu 8/13

2:22 pm-9:39 am

2 stops19h 17m

Charleston

Mon 8/24

6:15 am-6:44 pm

2 stops12h 29m

$505

Santo DomingoCharleston

SDQ - CHS

SDQCHS

Santo Domingo Las Americas

Fri 9/18

7:34 pm-11:52 am

2 stops16h 18m

Charleston

Fri 10/2

6:00 am-6:34 pm

1 stop12h 34m

$506

Santo DomingoCharleston

SDQ - CHS

SDQCHS

Santo Domingo Las Americas

Thu 8/13

2:00 pm-11:54 pm

1 stop9h 54m

Charleston

Mon 8/24

6:00 am-3:24 pm

1 stop9h 24m

$543

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Charleston from

How to get the cheapest flight ticket from Santo Domingo to Charleston

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest airline that flies from Santo Domingo Las Americas to Charleston?

JetBlue, Delta, and American Airlines are the most popular carriers operating from Santo Domingo Las Americas to Charleston

When to book flights from Santo Domingo to Charleston

Are you open to changing your travel dates? Check out the ideal times to fly from Santo Domingo to Charleston according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Santo Domingo to Charleston (SDQ to CHS) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Santo Domingo to Charleston

Fastest flight time

7h 18m

Direct flights

None
The fastest flight from Santo Domingo to Charleston takes 7h 18m
There are no direct flights from Santo Domingo to Charleston. There are no popular flight routes from Santo Domingo to Charleston.
Search flight deals

Frequently asked questions about flying from Santo Domingo to Charleston

  • How far is Santo Domingo Las Americas to Charleston by plane?

    A flight from Santo Domingo Las Americas to Charleston will travel around 1165.2 mi. Flights usually cover this in 7h 18m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Santo Domingo Las Americas Airport to Charleston Airport?

    Prices for flights from Santo Domingo Las Americas Airport to Charleston Airport refresh daily.

  • How old do you have to be to fly from Santo Domingo Las Americas Airport to Charleston Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Santo Domingo Las Americas Airport to Charleston Airport.

  • What documentation or ID do you need to fly to Charleston Airport?

    The travel and health documents required for your trip to Charleston Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Charleston Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Traveling to a place near Charleston?

Book flights to Charleston if you plan to visit one of these locations
Folly Beach
North Charleston
Summerville
Isle of Palms
Mount Pleasant
Kiawah Island
Walterboro
Santee
Goose Creek
Edisto Island
Edisto Beach
Seabrook Island

Why use momondo?

Why should I use momondo to find a flight deal from Santo Domingo to Charleston?

It is quick and easy to find Santo Domingo to Charleston flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Charleston that suits you.

Can I find flights from Santo Domingo to Charleston with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Santo Domingo to Charleston flights to just show those with flexible booking policies.

How can momondo help me find flights from Santo Domingo to Charleston?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Charleston from Santo Domingo.

I’m not ready to book a flight from Santo Domingo to Charleston right now. Can momondo alert me if prices change?

Price alerts on flights to Charleston from Santo Domingo are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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