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Cheap flights from Santo Domingo to Charleston from $207

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Santo Domingo to Charleston departing on 7/4. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Find the cheapest flights from Santo Domingo to Charleston

Cheap round-trip flights

Enter your travel dates to find the best prices.
Delta Logo
6:05 am - 4:42 pm
SDQ
-
CHS
10h 37m
1 stop
Delta Logo
5:10 am - 1:28 pm
CHS
-
SDQ
8h 18m
1 stop
$391Delta
Tue, Jul 14 - Tue, Aug 4
JetBlue Logo
5:01 am - 4:47 pm
SDQ
-
CHS
11h 46m
1 stop
JetBlue Logo
5:27 pm - 11:59 pm
CHS
-
SDQ
6h 32m
1 stop
$410JetBlue
Fri, Aug 28 - Tue, Sep 1
American Airlines Logo
10:27 am - 5:30 pm
SDQ
-
CHS
7h 03m
1 stop
American Airlines Logo
6:30 pm - 3:17 pm
CHS
-
SDQ
20h 47m
1 stop
$417American Airlines
Fri, Sep 18 - Fri, Oct 2
American Airlines Logo
4:20 pm - 11:43 pm
SDQ
-
CHS
7h 23m
1 stop
American Airlines Logo
6:30 pm - 6:34 pm
CHS
-
SDQ
24h 04m
1 stop
$418American Airlines
Fri, Sep 18 - Fri, Oct 2
American Airlines Logo
2:15 pm - 5:30 pm
SDQ
-
CHS
27h 15m
1 stop
American Airlines Logo
6:39 pm - 9:22 am
CHS
-
SDQ
14h 43m
2 stops
$421American Airlines
Fri, Sep 18 - Fri, Oct 2
American Airlines Logo
2:15 pm - 9:47 am
SDQ
-
CHS
19h 32m
2 stops
American Airlines Logo
6:39 pm - 9:22 am
CHS
-
SDQ
14h 43m
2 stops
$422American Airlines
Fri, Sep 18 - Fri, Oct 2
JetBlue Logo
10:10 am - 7:24 pm
SDQ
-
CHS
9h 14m
1 stop
JetBlue Logo
5:42 pm - 11:59 pm
CHS
-
SDQ
6h 17m
1 stop
$431JetBlue
Sat, Jul 18 - Mon, Aug 17
Delta Logo
2:53 pm - 10:07 pm
SDQ
-
CHS
7h 14m
1 stop
Delta Logo
12:59 pm - 12:54 am
CHS
-
SDQ
11h 55m
2 stops
$445Delta
Thu, Aug 20 - Wed, Aug 26
American Airlines Logo
7:40 pm - 10:22 am
SDQ
-
CHS
14h 42m
1 stop
American Airlines Logo
7:00 am - 6:44 pm
CHS
-
SDQ
11h 44m
1 stop
$457American Airlines
Mon, Jul 27 - Tue, Aug 18
American Airlines Logo
10:27 am - 11:55 pm
SDQ
-
CHS
13h 28m
2 stops
American Airlines Logo
7:34 pm - 1:22 pm
CHS
-
SDQ
17h 48m
1 stop
$458American Airlines
Tue, Jul 14 - Tue, Aug 4

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Delta flights from Santo Domingo to Charleston

Our best Delta deals on Santo Domingo to Charleston flight tickets
Delta
Jul 14
SDQ6:05 amSanto Domingo Las Americas
10h 37m
1 stop
CHS4:42 pmCharleston
Aug 4
CHS5:10 amCharleston
8h 18m
1 stop
SDQ1:28 pmSanto Domingo Las Americas
$391
Delta
Aug 20
SDQ2:53 pmSanto Domingo Las Americas
7h 14m
1 stop
CHS10:07 pmCharleston
Aug 26
CHS12:59 pmCharleston
11h 55m
2 stops
SDQ12:54 amSanto Domingo Las Americas
$445
Delta
Jul 14
SDQ6:05 amSanto Domingo Las Americas
10h 37m
1 stop
CHS4:42 pmCharleston
Aug 4
CHS5:10 amCharleston
12h 56m
2 stops
SDQ6:06 pmSanto Domingo Las Americas
$493

American Airlines flights from Santo Domingo to Charleston

Our best American Airlines deals on Santo Domingo to Charleston flight tickets
American Airlines
Sep 18
SDQ10:27 amSanto Domingo Las Americas
7h 03m
1 stop
CHS5:30 pmCharleston
Oct 2
CHS6:30 pmCharleston
20h 47m
1 stop
SDQ3:17 pmSanto Domingo Las Americas
$417
American Airlines
Sep 18
SDQ4:20 pmSanto Domingo Las Americas
7h 23m
1 stop
CHS11:43 pmCharleston
Oct 2
CHS6:30 pmCharleston
24h 04m
1 stop
SDQ6:34 pmSanto Domingo Las Americas
$418
American Airlines
Sep 18
SDQ2:15 pmSanto Domingo Las Americas
27h 15m
1 stop
CHS5:30 pmCharleston
Oct 2
CHS6:39 pmCharleston
14h 43m
2 stops
SDQ9:22 amSanto Domingo Las Americas
$421

momondo Fare Finder

 
Customize your flight search to find flights from Santo Domingo to Charleston that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated June 9, 2026.
Use the filters below to find and compare flights from Santo Domingo to Charleston that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Santo DomingoCharleston

SDQ - CHS

SDQCHS

Santo Domingo Las Americas

Tue 7/14

6:05 am-4:42 pm

1 stop10h 37m

Charleston

Tue 8/4

5:10 am-1:28 pm

1 stop8h 18m

$391

Santo DomingoCharleston

SDQ - CHS

SDQCHS

Santo Domingo Las Americas

Fri 8/28

5:01 am-4:47 pm

1 stop11h 46m

Charleston

Tue 9/1

5:27 pm-11:59 pm

1 stop6h 32m

$410

Santo DomingoCharleston

SDQ - CHS

SDQCHS

Santo Domingo Las Americas

Fri 9/18

10:27 am-5:30 pm

1 stop7h 03m

Charleston

Fri 10/2

6:30 pm-3:17 pm

1 stop20h 47m

$417

Santo DomingoCharleston

SDQ - CHS

SDQCHS

Santo Domingo Las Americas

Fri 9/18

4:20 pm-11:43 pm

1 stop7h 23m

Charleston

Fri 10/2

6:30 pm-6:34 pm

1 stop24h 04m

$418

Santo DomingoCharleston

SDQ - CHS

SDQCHS

Santo Domingo Las Americas

Fri 9/18

2:15 pm-5:30 pm

1 stop27h 15m

Charleston

Fri 10/2

6:39 pm-9:22 am

2 stops14h 43m

$421

Santo DomingoCharleston

SDQ - CHS

SDQCHS

Santo Domingo Las Americas

Fri 9/18

2:15 pm-9:47 am

2 stops19h 32m

Charleston

Fri 10/2

6:39 pm-9:22 am

2 stops14h 43m

$422
Quickest round-trip

Santo DomingoCharleston

SDQ - CHS

SDQCHS

Santo Domingo Las Americas

Sat 7/18

10:10 am-7:24 pm

1 stop9h 14m

Charleston

Mon 8/17

5:42 pm-11:59 pm

1 stop6h 17m

$431

Santo DomingoCharleston

SDQ - CHS

SDQCHS

Santo Domingo Las Americas

Thu 8/20

2:53 pm-10:07 pm

1 stop7h 14m

Charleston

Wed 8/26

12:59 pm-12:54 am

2 stops11h 55m

$445

Santo DomingoCharleston

SDQ - CHS

SDQCHS

Santo Domingo Las Americas

Mon 7/27

7:40 pm-10:22 am

1 stop14h 42m

Charleston

Tue 8/18

7:00 am-6:44 pm

1 stop11h 44m

$457

Santo DomingoCharleston

SDQ - CHS

SDQCHS

Santo Domingo Las Americas

Tue 7/14

10:27 am-11:55 pm

2 stops13h 28m

Charleston

Tue 8/4

7:34 pm-1:22 pm

1 stop17h 48m

$458

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Charleston from

How to get the cheapest flight ticket from Santo Domingo to Charleston

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest airline that flies from Santo Domingo Las Americas to Charleston?

Delta, United Airlines, and American Airlines are the most popular carriers operating from Santo Domingo Las Americas to Charleston

When to book flights from Santo Domingo to Charleston

Are you open to changing your travel dates? Check out the ideal times to fly from Santo Domingo to Charleston according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Santo Domingo to Charleston (SDQ to CHS) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Santo Domingo to Charleston

Fastest flight time

10h 37m

Direct flights

None
The fastest flight from Santo Domingo to Charleston takes 10h 37m
There are no direct flights from Santo Domingo to Charleston. There are no popular flight routes from Santo Domingo to Charleston.
Search flight deals

Frequently asked questions about flying from Santo Domingo to Charleston

  • How far is Santo Domingo Las Americas to Charleston by plane?

    A flight from Santo Domingo Las Americas to Charleston will travel around 1165.2 mi. Flights usually cover this in 10h 37m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Santo Domingo Las Americas Airport to Charleston Airport?

    Prices for flights from Santo Domingo Las Americas Airport to Charleston Airport refresh daily.

  • How old do you have to be to fly from Santo Domingo Las Americas Airport to Charleston Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Santo Domingo Las Americas Airport to Charleston Airport.

  • What documentation or ID do you need to fly to Charleston Airport?

    The travel and health documents required for your trip to Charleston Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Charleston Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Traveling to a place near Charleston?

Book flights to Charleston if you plan to visit one of these locations
Folly Beach
Isle of Palms
North Charleston
Summerville
Kiawah Island
Mount Pleasant
Edisto Island
Santee
Walterboro
Goose Creek
Edisto Beach
Seabrook Island

Why use momondo?

Why should I use momondo to find a flight deal from Santo Domingo to Charleston?

It is quick and easy to find Santo Domingo to Charleston flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Charleston that suits you.

Can I find flights from Santo Domingo to Charleston with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Santo Domingo to Charleston flights to just show those with flexible booking policies.

How can momondo help me find flights from Santo Domingo to Charleston?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Charleston from Santo Domingo.

I’m not ready to book a flight from Santo Domingo to Charleston right now. Can momondo alert me if prices change?

Price alerts on flights to Charleston from Santo Domingo are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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