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Cheap flights from Santo Domingo to Charleston from $220

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Santo Domingo to Charleston departing on 8/22. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Santo Domingo to Charleston (SDQ-CHS)

Cheap round-trip flights

American Airlines Logo
2:35 pm - 11:59 pmSDQ-CHS
9h 24m1 stop
American Airlines Logo
7:08 am - 8:30 pmCHS-SDQ
13h 22m1 stop
$485American Airlines
Find Deal
Tue, Sep 2 - Tue, Sep 9
American Airlines Logo
7:20 pm - 9:39 amSDQ-CHS
14h 19m1 stop
American Airlines Logo
6:00 am - 3:20 pmCHS-SDQ
9h 20m2 stops
$490American Airlines
Find Deal
Tue, Sep 2 - Tue, Sep 9
Logo
5:05 pm - 3:24 pmSDQ-CHS
22h 19m2 stops
Logo
2:59 pm - 4:00 pmCHS-SDQ
25h 01m3 stops
$556
Find Deal
Tue, Sep 2 - Tue, Sep 9
JetBlue Logo
2:05 am - 10:15 amSDQ-CHS
8h 10m1 stop
JetBlue Logo
11:10 am - 10:31 pmCHS-SDQ
11h 21m1 stop
$717JetBlue
Find Deal
Mon, Sep 1 - Tue, Sep 9

American Airlines flights from Santo Domingo to Charleston

Our best American Airlines deals on Santo Domingo to Charleston flight tickets
American Airlines
Sep 2
SDQ2:35 pmSanto Domingo Las Americas
9h 24m
1 stop
CHS11:59 pmCharleston
Sep 9
CHS7:08 amCharleston
13h 22m
1 stop
SDQ8:30 pmSanto Domingo Las Americas
$485
Find similar
American Airlines
Sep 2
SDQ7:20 pmSanto Domingo Las Americas
14h 19m
1 stop
CHS9:39 amCharleston
Sep 9
CHS6:00 amCharleston
9h 20m
2 stops
SDQ3:20 pmSanto Domingo Las Americas
$490
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Santo Domingo to Charleston that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 5, 2025.
Use the filters below to find and compare flights from Santo Domingo to Charleston that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Santo DomingoCharleston

SDQ - CHS

SDQCHS

Santo Domingo Las Americas

Tue 9/2

2:35 pm-11:59 pm

1 stop9h 24m

Charleston

Tue 9/9

7:08 am-8:30 pm

1 stop13h 22m

$485

Santo DomingoCharleston

SDQ - CHS

SDQCHS

Santo Domingo Las Americas

Tue 9/2

7:20 pm-9:39 am

1 stop14h 19m

Charleston

Tue 9/9

6:00 am-3:20 pm

2 stops9h 20m

$490

Santo DomingoCharleston

SDQ - CHS

SDQCHS

Santo Domingo Las Americas

Tue 9/2

5:05 pm-3:24 pm

2 stops22h 19m

Charleston

Tue 9/9

2:59 pm-4:00 pm

3 stops25h 01m

$556

Santo DomingoCharleston

SDQ - CHS

SDQCHS

Santo Domingo Las Americas

Mon 9/1

2:05 am-10:15 am

1 stop8h 10m

Charleston

Tue 9/9

11:10 am-10:31 pm

1 stop11h 21m

$717

Santo DomingoCharleston

SDQ - CHS

SDQCHS

Santo Domingo Las Americas

Fri 8/22

5:05 pm-6:46 pm

2 stops25h 41m

$220

Santo DomingoCharleston

SDQ - CHS

SDQCHS

Santo Domingo Las Americas

Tue 10/28

4:01 pm-7:04 pm

2 stops27h 03m

$225

Santo DomingoCharleston

SDQ - CHS

SDQCHS

Santo Domingo Las Americas

Fri 9/19

2:50 pm-11:48 pm

1 stop8h 58m

$250

Santo DomingoCharleston

SDQ - CHS

SDQCHS

Santo Domingo Las Americas

Mon 10/27

3:09 am-1:17 pm

1 stop10h 08m

$254

Santo DomingoCharleston

SDQ - CHS

SDQCHS

Santo Domingo Las Americas

Tue 10/28

4:01 pm-7:04 pm

3 stops27h 03m

$258

Santo DomingoCharleston

SDQ - CHS

SDQCHS

Santo Domingo Las Americas

Fri 8/22

6:05 am-8:45 am

1 stop26h 40m

$264

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 14 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Santo Domingo to Charleston

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to Charleston?

The cheapest day to depart from Santo Domingo to Charleston is on a Thursday. Travelers who choose to depart for Charleston on a Thursday will often find tickets for as low as $344. The most expensive day to fly to Charleston is Tuesday, with ticket prices averaging around $542.

What is the cheapest time of day to depart on your flight to Charleston?

The cheapest time of day to fly to Charleston is in the evening when flights can be purchased for as low as $365. In the morning is when there is more demand to fly to Charleston, so prices are often more expensive at around $542 per ticket.

When to book flights from Santo Domingo to Charleston

Are you open to changing your travel dates? Check out the ideal times to fly from Santo Domingo to Charleston according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Santo Domingo to Charleston (SDQ to CHS) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Santo Domingo to Charleston

Best Price Found

$220

Fastest flight time

8h 10m

Direct flights

None

Airports in Charleston

1 airport
The best one-way flight to Charleston from Santo Domingo in the past 72 hours is $220. The best round-trip flight deal from Santo Domingo to Charleston found on momondo in the last 72 hours is $485.
The fastest flight from Santo Domingo to Charleston takes 8h 10m
There are no direct flights from Santo Domingo to Charleston. Popular non-direct route for this connection is Santo Domingo Las Americas Airport - Charleston Airport.
There is 1 airport near Charleston: Charleston (CHS)
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  • How far is Santo Domingo Las Americas to Charleston by plane?

    A flight from Santo Domingo Las Americas to Charleston will travel around 1165.2 mi. Flights usually cover this in 8h 10m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Santo Domingo Las Americas Airport to Charleston Airport?

    Prices for flights from Santo Domingo Las Americas Airport to Charleston Airport refresh daily.

  • How many operators does momondo search for flights from Santo Domingo Las Americas Airport to Charleston Airport?

  • How old do you have to be to fly from Santo Domingo Las Americas Airport to Charleston Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Santo Domingo Las Americas Airport to Charleston Airport.

  • What documentation or ID do you need to fly to Charleston Airport?

    The travel and health documents required for your trip to Charleston Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Charleston Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular airline from Santo Domingo to Charleston?

Best airlines flying from Santo Domingo to Charleston

Compare and see reviews for airlines that fly from Santo Domingo to Charleston with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $264Free CancellationRating
8.0
7,985 reviews
Search Delta flights

Traveling to a place near Charleston?

Book flights to Charleston if you plan to visit one of these locations
Folly Beach
Isle of Palms
North Charleston
Kiawah Island
Mount Pleasant
Summerville
Edisto Island
Walterboro
Edisto Beach
Santee
Goose Creek
Seabrook Island

Why use momondo?

Why should I use momondo to find a flight deal from Santo Domingo to Charleston?

It is quick and easy to find Santo Domingo to Charleston flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Charleston that suits you.

Can I find flights from Santo Domingo to Charleston with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Santo Domingo to Charleston flights to just show those with flexible booking policies.

How can momondo help me find flights from Santo Domingo to Charleston?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Charleston from Santo Domingo.

I’m not ready to book a flight from Santo Domingo to Charleston right now. Can momondo alert me if prices change?

Price alerts on flights to Charleston from Santo Domingo are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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