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Cheap flights from Santo Domingo to Charleston from $163

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Santo Domingo to Charleston departing on 10/16. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Cheap round-trip flights

Delta Logo
6:45 am - 5:05 pmSDQ-CHS
11h 20m1 stop
Delta Logo
5:25 am - 2:42 pmCHS-SDQ
8h 17m1 stop
$320Delta
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Mon, Nov 10 - Fri, Nov 14
Delta Logo
7:49 pm - 10:34 amSDQ-CHS
14h 45m1 stop
Delta Logo
5:25 am - 2:42 pmCHS-SDQ
8h 17m1 stop
$338Delta
Find Deal
Fri, Oct 17 - Wed, Nov 12
United Airlines Logo
3:20 pm - 11:44 pmSDQ-CHS
8h 24m1 stop
United Airlines Logo
6:00 am - 3:06 pmCHS-SDQ
8h 06m1 stop
$361United Airlines
Find Deal
Wed, Oct 15 - Wed, Nov 12
Multiple Airlines Logo
3:54 pm - 9:06 amSDQ-CHS
17h 12m1 stop
Multiple Airlines Logo
2:59 pm - 5:50 pmCHS-SDQ
25h 51m2 stops
$364Multiple Airlines
Find Deal
Thu, Oct 16 - Tue, Nov 11
Multiple Airlines Logo
3:54 pm - 9:06 amSDQ-CHS
17h 12m1 stop
Multiple Airlines Logo
12:55 pm - 5:50 pmCHS-SDQ
27h 55m2 stops
$370Multiple Airlines
Find Deal
Thu, Oct 16 - Wed, Nov 12
JetBlue Logo
2:34 pm - 8:54 amSDQ-CHS
18h 20m1 stop
JetBlue Logo
5:20 pm - 2:17 pmCHS-SDQ
19h 57m1 stop
$402JetBlue
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Thu, Oct 16 - Wed, Nov 12
JetBlue Logo
4:10 am - 1:19 pmSDQ-CHS
10h 09m1 stop
JetBlue Logo
5:20 pm - 10:32 amCHS-SDQ
16h 12m1 stop
$410JetBlue
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Sun, Nov 9 - Fri, Nov 14
United Airlines Logo
4:18 pm - 11:45 pmSDQ-CHS
8h 27m1 stop
United Airlines Logo
2:30 pm - 11:46 pmCHS-SDQ
8h 16m1 stop
$419United Airlines
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Thu, Feb 5 - Sat, Feb 7
American Airlines Logo
4:20 pm - 11:59 pmSDQ-CHS
7h 39m1 stop
American Airlines Logo
9:25 am - 3:58 pmCHS-SDQ
5h 33m1 stop
$458American Airlines
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Tue, Oct 7 - Sun, Dec 7
American Airlines Logo
7:00 am - 4:54 pmSDQ-CHS
9h 54m2 stops
American Airlines Logo
6:00 am - 3:58 pmCHS-SDQ
8h 58m1 stop
$462American Airlines
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Tue, Oct 7 - Sun, Dec 7

United Airlines flights from Santo Domingo to Charleston

Our best United Airlines deals on Santo Domingo to Charleston flight tickets
United Airlines
Oct 15
SDQ3:20 pmSanto Domingo Las Americas
8h 24m
1 stop
CHS11:44 pmCharleston
Nov 12
CHS6:00 amCharleston
8h 06m
1 stop
SDQ3:06 pmSanto Domingo Las Americas
$361
Find similar
United Airlines
Feb 5
SDQ4:18 pmSanto Domingo Las Americas
8h 27m
1 stop
CHS11:45 pmCharleston
Feb 7
CHS2:30 pmCharleston
8h 16m
1 stop
SDQ11:46 pmSanto Domingo Las Americas
$419
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JetBlue flights from Santo Domingo to Charleston

Our best JetBlue deals on Santo Domingo to Charleston flight tickets
JetBlue
Oct 16
SDQ2:34 pmSanto Domingo Las Americas
18h 20m
1 stop
CHS8:54 amCharleston
Nov 12
CHS5:20 pmCharleston
19h 57m
1 stop
SDQ2:17 pmSanto Domingo Las Americas
$402
Find similar
JetBlue
Nov 9
SDQ4:10 amSanto Domingo Las Americas
10h 09m
1 stop
CHS1:19 pmCharleston
Nov 14
CHS5:20 pmCharleston
16h 12m
1 stop
SDQ10:32 amSanto Domingo Las Americas
$410
Find similar
JetBlue
Nov 21
SDQ4:09 amSanto Domingo Las Americas
13h 39m
1 stop
CHS4:48 pmCharleston
Nov 29
CHS8:30 pmCharleston
5h 00m
1 stop
SDQ2:30 amSanto Domingo Las Americas
$418
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momondo Fare Finder

 
Customize your flight search to find flights from Santo Domingo to Charleston that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated September 23, 2025.
Use the filters below to find and compare flights from Santo Domingo to Charleston that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Santo DomingoCharleston

SDQ - CHS

SDQCHS

Santo Domingo Las Americas

Mon 11/10

6:45 am-5:05 pm

1 stop11h 20m

Charleston

Fri 11/14

5:25 am-2:42 pm

1 stop8h 17m

$320

Santo DomingoCharleston

SDQ - CHS

SDQCHS

Santo Domingo Las Americas

Fri 10/17

7:49 pm-10:34 am

1 stop14h 45m

Charleston

Wed 11/12

5:25 am-2:42 pm

1 stop8h 17m

$338

Santo DomingoCharleston

SDQ - CHS

SDQCHS

Santo Domingo Las Americas

Wed 10/15

3:20 pm-11:44 pm

1 stop8h 24m

Charleston

Wed 11/12

6:00 am-3:06 pm

1 stop8h 06m

$361

Santo DomingoCharleston

SDQ - CHS

SDQCHS

Santo Domingo Las Americas

Thu 10/16

3:54 pm-9:06 am

1 stop17h 12m

Charleston

Tue 11/11

2:59 pm-5:50 pm

2 stops25h 51m

$364

Santo DomingoCharleston

SDQ - CHS

SDQCHS

Santo Domingo Las Americas

Thu 10/16

3:54 pm-9:06 am

1 stop17h 12m

Charleston

Wed 11/12

12:55 pm-5:50 pm

2 stops27h 55m

$370

Santo DomingoCharleston

SDQ - CHS

SDQCHS

Santo Domingo Las Americas

Thu 10/16

2:34 pm-8:54 am

1 stop18h 20m

Charleston

Wed 11/12

5:20 pm-2:17 pm

1 stop19h 57m

$402

Santo DomingoCharleston

SDQ - CHS

SDQCHS

Santo Domingo Las Americas

Sun 11/9

4:10 am-1:19 pm

1 stop10h 09m

Charleston

Fri 11/14

5:20 pm-10:32 am

1 stop16h 12m

$410

Santo DomingoCharleston

SDQ - CHS

SDQCHS

Santo Domingo Las Americas

Thu 2/5

4:18 pm-11:45 pm

1 stop8h 27m

Charleston

Sat 2/7

2:30 pm-11:46 pm

1 stop8h 16m

$419

Santo DomingoCharleston

SDQ - CHS

SDQCHS

Santo Domingo Las Americas

Tue 10/7

4:20 pm-11:59 pm

1 stop7h 39m

Charleston

Sun 12/7

9:25 am-3:58 pm

1 stop5h 33m

$458

Santo DomingoCharleston

SDQ - CHS

SDQCHS

Santo Domingo Las Americas

Tue 10/7

7:00 am-4:54 pm

2 stops9h 54m

Charleston

Sun 12/7

6:00 am-3:58 pm

1 stop8h 58m

$462

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Santo Domingo to Charleston

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Santo Domingo and Charleston?

What is the cheapest day to depart on your flight to Charleston?

The cheapest day to depart from Santo Domingo to Charleston is on a Thursday. Travelers who choose to depart for Charleston on a Thursday will often find tickets for as low as $344. The most expensive day to fly to Charleston is Tuesday, with ticket prices averaging around $542.

What is the cheapest time of day to depart on your flight to Charleston?

The cheapest time of day to fly to Charleston is in the evening when flights can be purchased for as low as $365. In the morning is when there is more demand to fly to Charleston, so prices are often more expensive at around $542 per ticket.

When to book flights from Santo Domingo to Charleston

Are you open to changing your travel dates? Check out the ideal times to fly from Santo Domingo to Charleston according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Santo Domingo to Charleston (SDQ to CHS) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Santo Domingo to Charleston

Direct flights

None
There are no direct flights from Santo Domingo to Charleston. There are no popular flight routes from Santo Domingo to Charleston.
Search flight deals

  • How far is Santo Domingo Las Americas to Charleston by plane?

    A flight from Santo Domingo Las Americas to Charleston will travel around 1165.2 mi. Flights usually cover this in 7h 01m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Santo Domingo Las Americas Airport to Charleston Airport?

    Prices for flights from Santo Domingo Las Americas Airport to Charleston Airport refresh daily.

  • How old do you have to be to fly from Santo Domingo Las Americas Airport to Charleston Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Santo Domingo Las Americas Airport to Charleston Airport.

  • What documentation or ID do you need to fly to Charleston Airport?

    The travel and health documents required for your trip to Charleston Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Charleston Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Traveling to a place near Charleston?

Book flights to Charleston if you plan to visit one of these locations
Folly Beach
Isle of Palms
North Charleston
Kiawah Island
Summerville
Mount Pleasant
Edisto Island
Walterboro
Santee
Goose Creek
Edisto Beach
Seabrook Island

Why use momondo?

Why should I use momondo to find a flight deal from Santo Domingo to Charleston?

It is quick and easy to find Santo Domingo to Charleston flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Charleston that suits you.

Can I find flights from Santo Domingo to Charleston with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Santo Domingo to Charleston flights to just show those with flexible booking policies.

How can momondo help me find flights from Santo Domingo to Charleston?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Charleston from Santo Domingo.

I’m not ready to book a flight from Santo Domingo to Charleston right now. Can momondo alert me if prices change?

Price alerts on flights to Charleston from Santo Domingo are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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