Cheap flights from Santiago to Cartagena from $157

In general, March is the cheapest month to fly from Santiago to Cartagena. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $382. If you’re not able to fly to Cartagena in March, then November is your next best option. Flight prices from Santiago to Cartagena during November average around $408.

Fly from Santiago Arturo Merino Benitez to Cartagena Rafael Nunez for the best Santiago Arturo Merino Benitez - Cartagena Rafael Nunez flight prices

You are more likely to see cheaper flights to Cartagena from Santiago when booking weeks ahead of your departure date. In general, you can expect to find flights to Cartagena for around $452 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Cartagena from Santiago for as low as $381 on momondo.

There is only 1 cabin class available to choose from on Santiago to Cartagena flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

You could potentially save up to 53% on your flight if you consider stops on a Santiago to Cartagena flight.

As of September 2026, prices for Santiago to Cartagena flights are approximately 10% more expensive when compared to flights at the same time last year.

JetSMART is the most popular carrier operating from Santiago Arturo Merino Benitez to Cartagena Rafael Nunez

JetSMART, Avianca and LATAM Airlines are the top three most popular airlines that fly to Cartagena from Santiago according to our data. JetSMART is the first choice among our users, with 50% of people opting to fly with this airline when traveling to Cartagena. Keep in mind that there are 3 different airlines that fly to Cartagena on a routine basis, so you have a few additional options to choose from.

Historically, on average around 8% of flights between Santiago and Cartagena have experienced a delay on any given week. The average delay length over the past 12 months has been 274 minutes.

Generally, flights departing at night tend to experience fewer delays. Flights at night have, in the past, seen delays more frequently in comparison.

Thursday is statistically the day of the week which experiences the fewest number of delays on this flight route. Monday has historically seen more delays on average compared to the rest of the week.

According to our data, Avianca have had the least number of delays on this route over the last 12 months; with about 8% of their flights experiencing any sort of delay.

Lima (LIM) was the most common stop: 67% of momondo users choosing 1-stop flights on this route connected there.

Flights via Lima (LIM) offer the lowest average round-trip price of $364.

Flights connecting via Panama City (PTY) have the shortest average one-way travel time: 9h 34m.

Panama City (PTY) has the shortest average layover time for this route: 2h 14m.