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Cheap flights from Santiago de los Caballeros to Panama City from $397

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Santiago de los Caballeros to Panama City departing on 5/13. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

Find the cheapest flights from Santiago de los Caballeros to Panama City

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
1:32 pm - 10:03 am
STI
-
ECP
21h 31m
2 stops
American Airlines Logo
2:36 pm - 12:20 pm
ECP
-
STI
20h 44m
2 stops
$689American Airlines
Fri, May 15 - Tue, Sep 15
American Airlines Logo
1:32 pm - 10:03 am
STI
-
ECP
21h 31m
2 stops
American Airlines Logo
2:36 pm - 12:20 pm
ECP
-
STI
20h 44m
2 stops
$704American Airlines
Fri, May 15 - Thu, Sep 17
American Airlines Logo
1:32 pm - 10:03 am
STI
-
ECP
21h 31m
2 stops
American Airlines Logo
3:29 pm - 12:20 pm
ECP
-
STI
19h 51m
2 stops
$705American Airlines
Fri, May 15 - Thu, Sep 17
American Airlines Logo
9:06 am - 10:36 pm
STI
-
ECP
14h 30m
2 stops
American Airlines Logo
3:48 pm - 2:38 pm
ECP
-
STI
21h 50m
2 stops
$712American Airlines
Tue, Jun 9 - Sat, Jun 13
American Airlines Logo
1:21 pm - 12:45 pm
STI
-
ECP
24h 24m
1 stop
American Airlines Logo
3:48 pm - 2:38 pm
ECP
-
STI
21h 50m
2 stops
$723American Airlines
Tue, Jun 9 - Sat, Jun 13
American Airlines Logo
1:32 pm - 10:03 am
STI
-
ECP
21h 31m
2 stops
American Airlines Logo
3:29 pm - 12:20 pm
ECP
-
STI
19h 51m
2 stops
$752American Airlines
Thu, May 14 - Thu, Sep 17
American Airlines Logo
1:32 pm - 12:36 pm
STI
-
ECP
24h 04m
2 stops
American Airlines Logo
7:00 pm - 12:20 pm
ECP
-
STI
16h 20m
2 stops
$754American Airlines
Fri, May 15 - Thu, Sep 17
American Airlines Logo
1:32 pm - 11:46 pm
STI
-
ECP
11h 14m
2 stops
American Airlines Logo
7:00 pm - 12:20 pm
ECP
-
STI
16h 20m
3 stops
$3,129American Airlines
Fri, May 15 - Tue, Sep 15
American Airlines Logo
1:32 pm - 11:46 pm
STI
-
ECP
11h 14m
2 stops
American Airlines Logo
7:00 pm - 12:20 pm
ECP
-
STI
16h 20m
3 stops
$3,146American Airlines
Fri, May 15 - Thu, Sep 17
American Airlines Logo
1:32 pm - 11:46 pm
STI
-
ECP
11h 14m
2 stops
American Airlines Logo
7:00 pm - 12:20 pm
ECP
-
STI
16h 20m
3 stops
$3,150American Airlines
Fri, May 15 - Thu, Sep 17

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American Airlines flights from Santiago de los Caballeros to Panama City, Florida

Our best American Airlines deals on Santiago de los Caballeros to Panama City, Florida flight tickets
American Airlines
May 15
STI1:32 pmSantiago de los Caballeros
21h 31m
2 stops
ECP10:03 amPanama City NW Florida Beaches
Sep 15
ECP2:36 pmPanama City NW Florida Beaches
20h 44m
2 stops
STI12:20 pmSantiago de los Caballeros
$689
American Airlines
May 15
STI1:32 pmSantiago de los Caballeros
21h 31m
2 stops
ECP10:03 amPanama City NW Florida Beaches
Sep 17
ECP2:36 pmPanama City NW Florida Beaches
20h 44m
2 stops
STI12:20 pmSantiago de los Caballeros
$704
American Airlines
May 15
STI1:32 pmSantiago de los Caballeros
21h 31m
2 stops
ECP10:03 amPanama City NW Florida Beaches
Sep 17
ECP3:29 pmPanama City NW Florida Beaches
19h 51m
2 stops
STI12:20 pmSantiago de los Caballeros
$705

United Airlines flights from Santiago de los Caballeros to Panama City, Florida

Our best United Airlines deals on Santiago de los Caballeros to Panama City, Florida flight tickets
United Airlines
Apr 29
STI2:07 pmSantiago de los Caballeros
20h 37m
3 stops
ECP9:44 amPanama City NW Florida Beaches
May 3
ECP10:34 amPanama City NW Florida Beaches
11h 18m
2 stops
STI10:52 pmSantiago de los Caballeros
$7,387
United Airlines
Jun 9
STI2:07 pmSantiago de los Caballeros
20h 37m
3 stops
ECP9:44 amPanama City NW Florida Beaches
Jun 13
ECP10:25 amPanama City NW Florida Beaches
11h 27m
2 stops
STI10:52 pmSantiago de los Caballeros
$7,418

momondo Fare Finder

 
Customize your flight search to find flights from Santiago de los Caballeros to Panama City, Florida that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated April 21, 2026.
Use the filters below to find and compare flights from Santiago de los Caballeros to Panama City, Florida that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Santiago de los CaballerosPanama City

STI - ECP

STIECP

Santiago de los Caballeros

Fri 5/15

1:32 pm-10:03 am

2 stops21h 31m

Panama City NW Florida Beaches

Tue 9/15

2:36 pm-12:20 pm

2 stops20h 44m

$689

Santiago de los CaballerosPanama City

STI - ECP

STIECP

Santiago de los Caballeros

Fri 5/15

1:32 pm-10:03 am

2 stops21h 31m

Panama City NW Florida Beaches

Thu 9/17

2:36 pm-12:20 pm

2 stops20h 44m

$704

Santiago de los CaballerosPanama City

STI - ECP

STIECP

Santiago de los Caballeros

Fri 5/15

1:32 pm-10:03 am

2 stops21h 31m

Panama City NW Florida Beaches

Thu 9/17

3:29 pm-12:20 pm

2 stops19h 51m

$705

Santiago de los CaballerosPanama City

STI - ECP

STIECP

Santiago de los Caballeros

Tue 6/9

9:06 am-10:36 pm

2 stops14h 30m

Panama City NW Florida Beaches

Sat 6/13

3:48 pm-2:38 pm

2 stops21h 50m

$712

Santiago de los CaballerosPanama City

STI - ECP

STIECP

Santiago de los Caballeros

Tue 6/9

1:21 pm-12:45 pm

1 stop24h 24m

Panama City NW Florida Beaches

Sat 6/13

3:48 pm-2:38 pm

2 stops21h 50m

$723

Santiago de los CaballerosPanama City

STI - ECP

STIECP

Santiago de los Caballeros

Thu 5/14

1:32 pm-10:03 am

2 stops21h 31m

Panama City NW Florida Beaches

Thu 9/17

3:29 pm-12:20 pm

2 stops19h 51m

$752

Santiago de los CaballerosPanama City

STI - ECP

STIECP

Santiago de los Caballeros

Fri 5/15

1:32 pm-12:36 pm

2 stops24h 04m

Panama City NW Florida Beaches

Thu 9/17

7:00 pm-12:20 pm

2 stops16h 20m

$754
Quickest round-trip

Santiago de los CaballerosPanama City

STI - ECP

STIECP

Santiago de los Caballeros

Fri 5/15

1:32 pm-11:46 pm

2 stops11h 14m

Panama City NW Florida Beaches

Tue 9/15

7:00 pm-12:20 pm

3 stops16h 20m

$3,129

Santiago de los CaballerosPanama City

STI - ECP

STIECP

Santiago de los Caballeros

Fri 5/15

1:32 pm-11:46 pm

2 stops11h 14m

Panama City NW Florida Beaches

Thu 9/17

7:00 pm-12:20 pm

3 stops16h 20m

$3,146

Santiago de los CaballerosPanama City

STI - ECP

STIECP

Santiago de los Caballeros

Fri 5/15

1:32 pm-11:46 pm

2 stops11h 14m

Panama City NW Florida Beaches

Thu 9/17

7:00 pm-12:20 pm

3 stops16h 20m

$3,150

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Panama City from

How to get the cheapest flight ticket from Santiago de los Caballeros to Panama City, Florida

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest airline that flies from Santiago de los Caballeros to Panama City NW Florida Beaches?

Delta is the most popular carrier operating from Santiago de los Caballeros to Panama City NW Florida Beaches

When to book flights from Santiago de los Caballeros to Panama City, Florida

Are you open to changing your travel dates? Check out the ideal times to fly from Santiago de los Caballeros to Panama City, Florida according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Santiago de los Caballeros to Panama City, Florida (STI to ECP) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Santiago de los Caballeros to Panama City, Florida

Fastest flight time

16h 22m

Direct flights

None
The fastest flight from Santiago de los Caballeros to Panama City, Florida takes 16h 22m
There are no direct flights from Santiago de los Caballeros to Panama City, Florida. There are no popular flight routes from Santiago de los Caballeros to Panama City, Florida.
Search flight deals

Frequently asked questions about flying from Santiago de los Caballeros to Panama City, Florida

  • How far is Santiago de los Caballeros to Panama City NW Florida Beaches by plane?

    There are 1192.0 mi between Santiago de los Caballeros and Panama City NW Florida Beaches. 16h 22m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Santiago de los Caballeros Airport to Panama City NW Florida Beaches Airport?

    Prices for flights from Santiago de los Caballeros Airport to Panama City NW Florida Beaches Airport are updated daily.

  • How old do you have to be to fly from Santiago de los Caballeros Airport to Panama City NW Florida Beaches Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Santiago de los Caballeros Airport to Panama City NW Florida Beaches Airport.

  • What documentation or ID do you need to fly to Panama City NW Florida Beaches Airport?

    The necessary travel and health documents for your Panama City NW Florida Beaches Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
Panama City Beach
Rosemary Beach
Port St. Joe
Seaside
Mexico Beach
Seagrove Beach
Freeport

Why use momondo?

Why should I use momondo to find a flight deal from Santiago de los Caballeros to Panama City?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Santiago de los Caballeros to Panama City. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Santiago de los Caballeros to Panama City with flexible booking policies on momondo?

momondo does allow users to show only those flights to Panama City from Santiago de los Caballeros which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Santiago de los Caballeros to Panama City?

Once you have performed a search for Santiago de los Caballeros to Panama City flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Santiago de los Caballeros to Panama City right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Panama City, momondo offers a useful price alert feature which will track prices for flights to Panama City from Santiago de los Caballeros and alert you when they change.

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