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Cheap flights from Santa Cruz de la Sierra to Chicago from $443

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Santa Cruz de la Sierra to Chicago departing on 5/20. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Find the cheapest flights from Santa Cruz de la Sierra to Chicago

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
3:35 am - 11:56 pm
VVI
-
ORD
21h 21m
2 stops
Multiple Airlines Logo
11:20 pm - 2:30 am
ORD
-
VVI
26h 10m
1 stop
$730Multiple Airlines
Sun, May 10 - Sat, May 16
Multiple Airlines Logo
1:12 am - 4:50 pm
VVI
-
ORD
40h 38m
2 stops
Multiple Airlines Logo
11:20 pm - 2:30 am
ORD
-
VVI
26h 10m
1 stop
$775Multiple Airlines
Tue, May 5 - Tue, May 12
Multiple Airlines Logo
3:35 am - 4:50 pm
VVI
-
ORD
38h 15m
2 stops
Multiple Airlines Logo
9:20 am - 4:50 am
ORD
-
VVI
18h 30m
1 stop
$784Multiple Airlines
Tue, May 5 - Mon, May 25
Multiple Airlines Logo
3:35 am - 11:15 pm
VVI
-
ORD
20h 40m
2 stops
Multiple Airlines Logo
11:20 pm - 2:30 am
ORD
-
VVI
26h 10m
1 stop
$794Multiple Airlines
Tue, May 12 - Sat, May 16
Multiple Airlines Logo
3:35 am - 6:38 pm
VVI
-
ORD
40h 03m
3 stops
Multiple Airlines Logo
11:20 pm - 2:30 am
ORD
-
VVI
26h 10m
1 stop
$799Multiple Airlines
Tue, May 5 - Tue, May 12
Multiple Airlines Logo
3:35 am - 11:56 pm
VVI
-
ORD
21h 21m
2 stops
Multiple Airlines Logo
9:20 am - 4:50 am
ORD
-
VVI
18h 30m
1 stop
$806Multiple Airlines
Thu, May 7 - Mon, May 25
Multiple Airlines Logo
3:35 am - 11:56 pm
VVI
-
ORD
21h 21m
2 stops
Multiple Airlines Logo
4:50 pm - 2:30 am
ORD
-
VVI
32h 40m
3 stops
$809Multiple Airlines
Sun, May 10 - Sat, May 16
Multiple Airlines Logo
3:35 am - 4:50 pm
VVI
-
ORD
38h 15m
2 stops
Multiple Airlines Logo
9:20 am - 4:50 am
ORD
-
VVI
18h 30m
1 stop
$812Multiple Airlines
Tue, May 5 - Sun, May 31
Multiple Airlines Logo
3:35 am - 11:56 pm
VVI
-
ORD
21h 21m
2 stops
Multiple Airlines Logo
5:05 am - 2:30 am
ORD
-
VVI
20h 25m
2 stops
$814Multiple Airlines
Sun, May 10 - Sun, May 17
Multiple Airlines Logo
3:35 am - 4:50 pm
VVI
-
ORD
38h 15m
2 stops
Multiple Airlines Logo
9:20 am - 4:50 am
ORD
-
VVI
18h 30m
1 stop
$828Multiple Airlines
Tue, May 5 - Thu, May 28

Copa Airlines flights from Santa Cruz de la Sierra to Chicago

Our best Copa Airlines deals on Santa Cruz de la Sierra to Chicago flight tickets
Copa Airlines
May 7
VVI11:47 amSanta Cruz de la Sierra Viru Viru Intl
14h 28m
1 stop
ORD1:15 amChicago O'Hare Intl
May 28
ORD8:02 amChicago O'Hare Intl
13h 36m
1 stop
VVI10:38 pmSanta Cruz de la Sierra Viru Viru Intl
$886
Copa Airlines
Aug 1
VVI11:47 amSanta Cruz de la Sierra Viru Viru Intl
13h 15m
1 stop
ORD12:02 amChicago O'Hare Intl
Sep 8
ORD8:01 amChicago O'Hare Intl
13h 43m
1 stop
VVI10:44 pmSanta Cruz de la Sierra Viru Viru Intl
$912

United Airlines flights from Santa Cruz de la Sierra to Chicago

Our best United Airlines deals on Santa Cruz de la Sierra to Chicago flight tickets
United Airlines
May 2
VVI11:47 amSanta Cruz de la Sierra Viru Viru Intl
21h 57m
2 stops
ORD8:44 amChicago O'Hare Intl
May 31
ORD7:38 amChicago O'Hare Intl
18h 53m
2 stops
VVI3:31 amSanta Cruz de la Sierra Viru Viru Intl
$880
United Airlines
May 7
VVI11:47 amSanta Cruz de la Sierra Viru Viru Intl
20h 39m
2 stops
ORD7:26 amChicago O'Hare Intl
May 28
ORD9:40 pmChicago O'Hare Intl
23h 58m
2 stops
VVI10:38 pmSanta Cruz de la Sierra Viru Viru Intl
$889

momondo Fare Finder

 
Customize your flight search to find flights from Santa Cruz de la Sierra to Chicago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated April 12, 2026.
Use the filters below to find and compare flights from Santa Cruz de la Sierra to Chicago that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Santa Cruz de la SierraChicago

VVI - ORD

VVIORD

Santa Cruz de la Sierra Viru Viru Intl

Sun 5/10

3:35 am-11:56 pm

2 stops21h 21m

Chicago O'Hare Intl

Sat 5/16

11:20 pm-2:30 am

1 stop26h 10m

$730

Santa Cruz de la SierraChicago

VVI - ORD

VVIORD

Santa Cruz de la Sierra Viru Viru Intl

Tue 5/5

1:12 am-4:50 pm

2 stops40h 38m

Chicago O'Hare Intl

Tue 5/12

11:20 pm-2:30 am

1 stop26h 10m

$775

Santa Cruz de la SierraChicago

VVI - ORD

VVIORD

Santa Cruz de la Sierra Viru Viru Intl

Tue 5/5

3:35 am-4:50 pm

2 stops38h 15m

Chicago O'Hare Intl

Mon 5/25

9:20 am-4:50 am

1 stop18h 30m

$784

Santa Cruz de la SierraChicago

VVI - ORD

VVIORD

Santa Cruz de la Sierra Viru Viru Intl

Tue 5/12

3:35 am-11:15 pm

2 stops20h 40m

Chicago O'Hare Intl

Sat 5/16

11:20 pm-2:30 am

1 stop26h 10m

$794

Santa Cruz de la SierraChicago

VVI - ORD

VVIORD

Santa Cruz de la Sierra Viru Viru Intl

Tue 5/5

3:35 am-6:38 pm

3 stops40h 03m

Chicago O'Hare Intl

Tue 5/12

11:20 pm-2:30 am

1 stop26h 10m

$799
Quickest round-trip

Santa Cruz de la SierraChicago

VVI - ORD

VVIORD

Santa Cruz de la Sierra Viru Viru Intl

Thu 5/7

3:35 am-11:56 pm

2 stops21h 21m

Chicago O'Hare Intl

Mon 5/25

9:20 am-4:50 am

1 stop18h 30m

$806

Santa Cruz de la SierraChicago

VVI - ORD

VVIORD

Santa Cruz de la Sierra Viru Viru Intl

Sun 5/10

3:35 am-11:56 pm

2 stops21h 21m

Chicago O'Hare Intl

Sat 5/16

4:50 pm-2:30 am

3 stops32h 40m

$809

Santa Cruz de la SierraChicago

VVI - ORD

VVIORD

Santa Cruz de la Sierra Viru Viru Intl

Tue 5/5

3:35 am-4:50 pm

2 stops38h 15m

Chicago O'Hare Intl

Sun 5/31

9:20 am-4:50 am

1 stop18h 30m

$812

Santa Cruz de la SierraChicago

VVI - ORD

VVIORD

Santa Cruz de la Sierra Viru Viru Intl

Sun 5/10

3:35 am-11:56 pm

2 stops21h 21m

Chicago O'Hare Intl

Sun 5/17

5:05 am-2:30 am

2 stops20h 25m

$814

Santa Cruz de la SierraChicago

VVI - ORD

VVIORD

Santa Cruz de la Sierra Viru Viru Intl

Tue 5/5

3:35 am-4:50 pm

2 stops38h 15m

Chicago O'Hare Intl

Thu 5/28

9:20 am-4:50 am

1 stop18h 30m

$828

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Santa Cruz de la Sierra to Chicago

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Santa Cruz de la Sierra and Chicago?

Can stopping save me money on Santa Cruz de la Sierra to Chicago flights?

You could potentially save up to 22% on your flight if you consider stops on a Santa Cruz de la Sierra to Chicago flight.

When to book flights from Santa Cruz de la Sierra to Chicago

Are you open to changing your travel dates? Check out the ideal times to fly from Santa Cruz de la Sierra to Chicago according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Santa Cruz de la Sierra to Chicago (VVI to CHI) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Santa Cruz de la Sierra to Chicago

Fastest flight time

14h 15m

Direct flights

None
The fastest flight from Santa Cruz de la Sierra to Chicago takes 14h 15m
There are no direct flights from Santa Cruz de la Sierra to Chicago. There are no popular flight routes from Santa Cruz de la Sierra to Chicago.
Search flight deals

Frequently asked questions about flying from Santa Cruz de la Sierra to Chicago

  • How far is Santa Cruz de la Sierra Viru Viru Intl to Chicago by plane?

    A flight from Santa Cruz de la Sierra Viru Viru Intl to Chicago will travel around 4407.1 mi. Typically, this will take 14h 15m by plane in normal conditions.

  • When did momondo last update prices for flights from Santa Cruz de la Sierra Viru Viru Intl Airport to Chicago?

    Prices for flights from Santa Cruz de la Sierra Viru Viru Intl Airport to Chicago were last updated today.

  • How many operators does momondo search for flights from Santa Cruz de la Sierra Viru Viru Intl Airport to Chicago?

  • How old do you have to be to fly from Santa Cruz de la Sierra Viru Viru Intl Airport to Chicago?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Santa Cruz de la Sierra Viru Viru Intl Airport to Chicago.

  • What documentation or ID do you need to fly to Chicago?

    The required travel and health documents for your Chicago trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Chicago. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Santa Cruz de la Sierra to Chicago?

Best airlines flying from Santa Cruz de la Sierra to Chicago

Compare and see reviews for airlines that fly from Santa Cruz de la Sierra to Chicago with momondo
Airline
Rating
Free Cancellation
Price
Copa AirlinesPriceFrom $690Free CancellationRating
7.5
1,572 reviews
Search Copa Airlines flights

Traveling to a place near Chicago?

Book flights to Chicago if you plan to visit one of these locations
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Crown Point
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Porter
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Saint John

Why use momondo?

Why should I use momondo to find a flight deal from Santa Cruz de la Sierra to Chicago?

It is quick and easy to find Santa Cruz de la Sierra to Chicago flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Chicago that suits you.

Can I find flights from Santa Cruz de la Sierra to Chicago with flexible booking policies on momondo?

Yes. All flights to Chicago from Santa Cruz de la Sierra on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Santa Cruz de la Sierra to Chicago?

Once you have performed a search for Santa Cruz de la Sierra to Chicago flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Santa Cruz de la Sierra to Chicago right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Santa Cruz de la Sierra to Chicago now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Chicago and let you know when they change.

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Find better results for your trip to the United States

Fly into one of these airports located in Chicago

Airports listed have a maximum distance of 78.5 mi from Chicago
Chicago Midway Airport
Chicago O'Hare Intl Airport
Chicago Greater Rockford Airport