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Cheap flights from Santa Ana, California to Santiago from $643

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Santa Ana, California to Santiago departing on 12/10. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Cheap round-trip flights

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American Airlines Logo
8:30 am - 7:45 amSNA-SCL
18h 15m1 stop
American Airlines Logo
11:15 pm - 5:59 pmSCL-SNA
23h 44m1 stop
$814American Airlines
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Mon, Dec 8 - Mon, Dec 15
American Airlines Logo
9:59 am - 8:55 amSNA-SCL
17h 56m2 stops
American Airlines Logo
11:55 pm - 2:09 pmSCL-SNA
19h 14m2 stops
$819American Airlines
Find Deal
Mon, Dec 8 - Mon, Dec 15
United Airlines Logo
11:05 am - 8:50 amSNA-SCL
16h 45m2 stops
United Airlines Logo
10:45 pm - 8:50 pmSCL-SNA
27h 05m2 stops
$887United Airlines
Find Deal
Mon, Feb 9 - Fri, Feb 27
LATAM Airlines Logo
6:45 am - 3:30 pmSNA-SCL
27h 45m2 stops
LATAM Airlines Logo
7:15 am - 11:49 amSCL-SNA
33h 34m3 stops
$1,016LATAM Airlines
Find Deal
Mon, Feb 9 - Fri, Feb 27
Delta Logo
9:20 pm - 7:40 amSNA-SCL
29h 20m1 stop
Delta Logo
12:20 am - 10:19 pmSCL-SNA
26h 59m2 stops
$1,063Delta
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Mon, Feb 9 - Thu, Feb 26
United Airlines Logo
8:00 am - 7:50 amSNA-SCL
19h 50m1 stop
United Airlines Logo
9:45 pm - 11:30 amSCL-SNA
17h 45m1 stop
$1,074United Airlines
Find Deal
Tue, Mar 17 - Thu, Mar 19
Delta Logo
6:45 am - 3:30 pmSNA-SCL
27h 45m2 stops
Delta Logo
12:20 am - 8:08 pmSCL-SNA
24h 48m2 stops
$1,112Delta
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Mon, Feb 9 - Thu, Feb 26
LATAM Airlines Logo
6:45 am - 6:10 amSNA-SCL
18h 25m1 stop
LATAM Airlines Logo
3:00 pm - 1:05 pmSCL-SNA
27h 05m2 stops
$1,173LATAM Airlines
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Wed, Dec 17 - Sat, Dec 27
Air Canada Logo
12:25 pm - 6:50 amSNA-SCL
37h 25m2 stops
Air Canada Logo
8:55 pm - 11:25 amSCL-SNA
43h 30m2 stops
$4,452Air Canada
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Wed, Dec 17 - Sat, Jan 3
Air Canada Logo
12:25 pm - 12:15 pmSNA-SCL
42h 50m2 stops
Air Canada Logo
8:55 pm - 11:25 amSCL-SNA
43h 30m2 stops
$5,043Air Canada
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Thu, Dec 18 - Sat, Jan 3

Air Canada flights from Santa Ana, California to Santiago

Our best Air Canada deals on Santa Ana, California to Santiago flight tickets
Air Canada
Dec 17
SNA12:25 pmSanta Ana J. Wayne/Orange Cnty
37h 25m
2 stops
SCL6:50 amSantiago Arturo Merino Benitez
Jan 3
SCL8:55 pmSantiago Arturo Merino Benitez
43h 30m
2 stops
SNA11:25 amSanta Ana J. Wayne/Orange Cnty
$4,452
Find similar
Air Canada
Dec 18
SNA12:25 pmSanta Ana J. Wayne/Orange Cnty
42h 50m
2 stops
SCL12:15 pmSantiago Arturo Merino Benitez
Jan 3
SCL8:55 pmSantiago Arturo Merino Benitez
43h 30m
2 stops
SNA11:25 amSanta Ana J. Wayne/Orange Cnty
$5,043
Find similar
Air Canada
Dec 19
SNA10:52 amSanta Ana J. Wayne/Orange Cnty
20h 23m
2 stops
SCL12:15 pmSantiago Arturo Merino Benitez
Jan 3
SCL8:55 pmSantiago Arturo Merino Benitez
27h 01m
2 stops
SNA6:56 pmSanta Ana J. Wayne/Orange Cnty
$19,374
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LATAM Airlines flights from Santa Ana, California to Santiago

Our best LATAM Airlines deals on Santa Ana, California to Santiago flight tickets
LATAM Airlines
Feb 9
SNA6:45 amSanta Ana J. Wayne/Orange Cnty
27h 45m
2 stops
SCL3:30 pmSantiago Arturo Merino Benitez
Feb 27
SCL7:15 amSantiago Arturo Merino Benitez
33h 34m
3 stops
SNA11:49 amSanta Ana J. Wayne/Orange Cnty
$1,016
Find similar
LATAM Airlines
Dec 17
SNA6:45 amSanta Ana J. Wayne/Orange Cnty
18h 25m
1 stop
SCL6:10 amSantiago Arturo Merino Benitez
Dec 27
SCL3:00 pmSantiago Arturo Merino Benitez
27h 05m
2 stops
SNA1:05 pmSanta Ana J. Wayne/Orange Cnty
$1,173
Find similar
LATAM Airlines
Feb 18
SNA12:04 pmSanta Ana J. Wayne/Orange Cnty
13h 56m
1 stop
SCL7:00 amSantiago Arturo Merino Benitez
Mar 10
SCL11:15 pmSantiago Arturo Merino Benitez
16h 19m
1 stop
SNA11:34 amSanta Ana J. Wayne/Orange Cnty
$1,409
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momondo Fare Finder

 
Customize your flight search to find flights from Santa Ana, California to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated November 5, 2025.
Use the filters below to find and compare flights from Santa Ana, California to Santiago that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Santa AnaSantiago

SNA - SCL

SNASCL

Santa Ana J. Wayne/Orange Cnty

Mon 12/8

8:30 am-7:45 am

1 stop18h 15m

Santiago Arturo Merino Benitez

Mon 12/15

11:15 pm-5:59 pm

1 stop23h 44m

$814

Santa AnaSantiago

SNA - SCL

SNASCL

Santa Ana J. Wayne/Orange Cnty

Mon 12/8

9:59 am-8:55 am

2 stops17h 56m

Santiago Arturo Merino Benitez

Mon 12/15

11:55 pm-2:09 pm

2 stops19h 14m

$819

Santa AnaSantiago

SNA - SCL

SNASCL

Santa Ana J. Wayne/Orange Cnty

Mon 2/9

11:05 am-8:50 am

2 stops16h 45m

Santiago Arturo Merino Benitez

Fri 2/27

10:45 pm-8:50 pm

2 stops27h 05m

$887

Santa AnaSantiago

SNA - SCL

SNASCL

Santa Ana J. Wayne/Orange Cnty

Mon 2/9

6:45 am-3:30 pm

2 stops27h 45m

Santiago Arturo Merino Benitez

Fri 2/27

7:15 am-11:49 am

3 stops33h 34m

$1,016

Santa AnaSantiago

SNA - SCL

SNASCL

Santa Ana J. Wayne/Orange Cnty

Mon 2/9

9:20 pm-7:40 am

1 stop29h 20m

Santiago Arturo Merino Benitez

Thu 2/26

12:20 am-10:19 pm

2 stops26h 59m

$1,063

Santa AnaSantiago

SNA - SCL

SNASCL

Santa Ana J. Wayne/Orange Cnty

Tue 3/17

8:00 am-7:50 am

1 stop19h 50m

Santiago Arturo Merino Benitez

Thu 3/19

9:45 pm-11:30 am

1 stop17h 45m

$1,074

Santa AnaSantiago

SNA - SCL

SNASCL

Santa Ana J. Wayne/Orange Cnty

Mon 2/9

6:45 am-3:30 pm

2 stops27h 45m

Santiago Arturo Merino Benitez

Thu 2/26

12:20 am-8:08 pm

2 stops24h 48m

$1,112

Santa AnaSantiago

SNA - SCL

SNASCL

Santa Ana J. Wayne/Orange Cnty

Wed 12/17

6:45 am-6:10 am

1 stop18h 25m

Santiago Arturo Merino Benitez

Sat 12/27

3:00 pm-1:05 pm

2 stops27h 05m

$1,173

Santa AnaSantiago

SNA - SCL

SNASCL

Santa Ana J. Wayne/Orange Cnty

Wed 12/17

12:25 pm-6:50 am

2 stops37h 25m

Santiago Arturo Merino Benitez

Sat 1/3

8:55 pm-11:25 am

2 stops43h 30m

$4,452

Santa AnaSantiago

SNA - SCL

SNASCL

Santa Ana J. Wayne/Orange Cnty

Thu 12/18

12:25 pm-12:15 pm

2 stops42h 50m

Santiago Arturo Merino Benitez

Sat 1/3

8:55 pm-11:25 am

2 stops43h 30m

$5,043

Flights are sorted by cheapest round-trip flights first.

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How to get the cheapest flight ticket from Santa Ana, California to Santiago

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to Santiago?

The cheapest day to depart on your flight to Santiago is on a Monday when prices can be found for as low as $844. This is often the case because there is less demand to fly during this day of the week. Be sure to avoid booking your departure on a Saturday as prices are generally higher than usual. According to our data, the average ticket price to Santiago on Saturday is $1,062.

What is the cheapest time of day to depart on your flight to Santiago?

In the morning is the cheapest time of day to fly from Santa Ana, California to Santiago when you can find flight prices for as low as $850. Flying to Santiago in the morning is an ideal time because this is during off-peak travel hours. At noon is when there is more demand to fly to Santiago, so prices are often more expensive at around $1,025 per ticket.

When to book flights from Santa Ana, California to Santiago

Are you open to changing your travel dates? Check out the ideal times to fly from Santa Ana, California to Santiago according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Santa Ana, California to Santiago (SNA to SCL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Santa Ana, California to Santiago

Direct flights

None
There are no direct flights from Santa Ana, California to Santiago. There are no popular flight routes from Santa Ana, California to Santiago.
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  • How far is Santa Ana J. Wayne/Orange Cnty to Santiago Arturo Merino Benitez by plane?

    A flight from Santa Ana J. Wayne/Orange Cnty to Santiago Arturo Merino Benitez will travel around 5557.9 mi. By plane, this route typically takes 13h 55m.

  • When did momondo last update prices for flights from Santa Ana J. Wayne/Orange Cnty Airport to Santiago Arturo Merino Benitez Airport?

    Prices for flights from Santa Ana J. Wayne/Orange Cnty Airport to Santiago Arturo Merino Benitez Airport are refreshed on a daily basis.

  • How old do you have to be to fly from Santa Ana J. Wayne/Orange Cnty Airport to Santiago Arturo Merino Benitez Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Santa Ana J. Wayne/Orange Cnty Airport to Santiago Arturo Merino Benitez Airport.

  • What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?

    The travel and health documents required for your trip to Santiago Arturo Merino Benitez Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Santiago Arturo Merino Benitez Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Traveling to a place near Santiago?

Book flights to Santiago if you plan to visit one of these locations
Viña del Mar
Santa Cruz
Valparaíso
Valle Nevado
San Fernando
Pichilemu

Why use momondo?

Why should I use momondo to find a flight deal from Santa Ana to Santiago?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Santa Ana to Santiago for you.

Can I find flights from Santa Ana to Santiago with flexible booking policies on momondo?

momondo does allow users to show only those flights to Santiago from Santa Ana which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Santa Ana to Santiago?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Santiago from Santa Ana.

I’m not ready to book a flight from Santa Ana to Santiago right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Santiago, momondo offers a useful price alert feature which will track prices for flights to Santiago from Santa Ana and alert you when they change.

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