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Cheap flights from Santa Ana to Santiago from $645

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Santa Ana to Santiago departing on 1/14. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Cheap round-trip flights

American Airlines Logo
10:41 am - 7:45 amSNA-SCL
16h 04m1 stop
American Airlines Logo
11:15 pm - 4:02 pmSCL-SNA
21h 47m1 stop
$814American Airlines
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Mon, Dec 8 - Mon, Dec 15
American Airlines Logo
8:30 am - 8:55 amSNA-SCL
19h 25m2 stops
American Airlines Logo
10:30 pm - 12:38 pmSCL-SNA
19h 08m2 stops
$818American Airlines
Find Deal
Mon, Dec 8 - Mon, Dec 15
United Airlines Logo
8:15 am - 7:50 amSNA-SCL
19h 35m1 stop
United Airlines Logo
10:45 pm - 2:08 pmSCL-SNA
20h 23m1 stop
$894United Airlines
Find Deal
Fri, Oct 31 - Fri, Nov 7
United Airlines Logo
12:14 pm - 7:50 amSNA-SCL
15h 36m1 stop
United Airlines Logo
10:45 pm - 8:32 pmSCL-SNA
26h 47m2 stops
$898United Airlines
Find Deal
Fri, Oct 31 - Fri, Nov 7
LATAM Airlines Logo
12:26 pm - 7:40 amSNA-SCL
15h 14m1 stop
LATAM Airlines Logo
11:10 pm - 11:40 amSCL-SNA
17h 30m1 stop
$964LATAM Airlines
Find Deal
Tue, Oct 28 - Tue, Nov 18
LATAM Airlines Logo
6:45 am - 7:40 amSNA-SCL
19h 55m1 stop
LATAM Airlines Logo
11:10 pm - 11:06 amSCL-SNA
16h 56m1 stop
$965LATAM Airlines
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Thu, Dec 11 - Thu, Dec 25
Delta Logo
9:20 pm - 6:59 amSNA-SCL
29h 39m2 stops
Delta Logo
10:55 pm - 8:27 pmSCL-SNA
25h 32m2 stops
$1,117Delta
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Fri, Sep 26 - Sat, Oct 4
Delta Logo
9:20 pm - 7:00 amSNA-SCL
29h 40m1 stop
Delta Logo
10:55 pm - 8:27 pmSCL-SNA
25h 32m2 stops
$1,123Delta
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Fri, Sep 26 - Sat, Oct 4
Air Canada Logo
10:52 am - 12:15 pmSNA-SCL
44h 23m2 stops
Air Canada Logo
8:55 pm - 11:25 amSCL-SNA
43h 30m2 stops
$2,014Air Canada
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Sun, Dec 21 - Mon, Jan 5
Air Canada Logo
12:25 pm - 12:15 pmSNA-SCL
42h 50m2 stops
Air Canada Logo
8:55 pm - 11:25 amSCL-SNA
43h 30m2 stops
$2,114Air Canada
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Sat, Dec 20 - Mon, Jan 5

LATAM Airlines flights from Santa Ana to Santiago

Our best LATAM Airlines deals on Santa Ana to Santiago flight tickets
LATAM Airlines
Oct 28
SNA12:26 pmSanta Ana J. Wayne/Orange Cnty
15h 14m
1 stop
SCL7:40 amSantiago Arturo Merino Benitez
Nov 18
SCL11:10 pmSantiago Arturo Merino Benitez
17h 30m
1 stop
SNA11:40 amSanta Ana J. Wayne/Orange Cnty
$964
Find similar
LATAM Airlines
Dec 11
SNA6:45 amSanta Ana J. Wayne/Orange Cnty
19h 55m
1 stop
SCL7:40 amSantiago Arturo Merino Benitez
Dec 25
SCL11:10 pmSantiago Arturo Merino Benitez
16h 56m
1 stop
SNA11:06 amSanta Ana J. Wayne/Orange Cnty
$965
Find similar
LATAM Airlines
Sep 29
SNA1:52 pmSanta Ana J. Wayne/Orange Cnty
21h 08m
2 stops
SCL3:00 pmSantiago Arturo Merino Benitez
Oct 6
SCL5:55 pmSantiago Arturo Merino Benitez
21h 21m
2 stops
SNA11:16 amSanta Ana J. Wayne/Orange Cnty
$1,124
Find similar

American Airlines flights from Santa Ana to Santiago

Our best American Airlines deals on Santa Ana to Santiago flight tickets
American Airlines
Dec 8
SNA10:41 amSanta Ana J. Wayne/Orange Cnty
16h 04m
1 stop
SCL7:45 amSantiago Arturo Merino Benitez
Dec 15
SCL11:15 pmSantiago Arturo Merino Benitez
21h 47m
1 stop
SNA4:02 pmSanta Ana J. Wayne/Orange Cnty
$814
Find similar
American Airlines
Dec 8
SNA8:30 amSanta Ana J. Wayne/Orange Cnty
19h 25m
2 stops
SCL8:55 amSantiago Arturo Merino Benitez
Dec 15
SCL10:30 pmSantiago Arturo Merino Benitez
19h 08m
2 stops
SNA12:38 pmSanta Ana J. Wayne/Orange Cnty
$818
Find similar
American Airlines
Sep 26
SNA6:45 amSanta Ana J. Wayne/Orange Cnty
21h 10m
2 stops
SCL7:55 amSantiago Arturo Merino Benitez
Oct 4
SCL9:55 pmSantiago Arturo Merino Benitez
18h 05m
2 stops
SNA12:00 pmSanta Ana J. Wayne/Orange Cnty
$1,168
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momondo Fare Finder

 
Customize your flight search to find flights from Santa Ana to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated September 16, 2025.
Use the filters below to find and compare flights from Santa Ana to Santiago that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Santa AnaSantiago

SNA - SCL

SNASCL

Santa Ana J. Wayne/Orange Cnty

Mon 12/8

10:41 am-7:45 am

1 stop16h 04m

Santiago Arturo Merino Benitez

Mon 12/15

11:15 pm-4:02 pm

1 stop21h 47m

$814

Santa AnaSantiago

SNA - SCL

SNASCL

Santa Ana J. Wayne/Orange Cnty

Mon 12/8

8:30 am-8:55 am

2 stops19h 25m

Santiago Arturo Merino Benitez

Mon 12/15

10:30 pm-12:38 pm

2 stops19h 08m

$818

Santa AnaSantiago

SNA - SCL

SNASCL

Santa Ana J. Wayne/Orange Cnty

Fri 10/31

8:15 am-7:50 am

1 stop19h 35m

Santiago Arturo Merino Benitez

Fri 11/7

10:45 pm-2:08 pm

1 stop20h 23m

$894

Santa AnaSantiago

SNA - SCL

SNASCL

Santa Ana J. Wayne/Orange Cnty

Fri 10/31

12:14 pm-7:50 am

1 stop15h 36m

Santiago Arturo Merino Benitez

Fri 11/7

10:45 pm-8:32 pm

2 stops26h 47m

$898

Santa AnaSantiago

SNA - SCL

SNASCL

Santa Ana J. Wayne/Orange Cnty

Tue 10/28

12:26 pm-7:40 am

1 stop15h 14m

Santiago Arturo Merino Benitez

Tue 11/18

11:10 pm-11:40 am

1 stop17h 30m

$964

Santa AnaSantiago

SNA - SCL

SNASCL

Santa Ana J. Wayne/Orange Cnty

Thu 12/11

6:45 am-7:40 am

1 stop19h 55m

Santiago Arturo Merino Benitez

Thu 12/25

11:10 pm-11:06 am

1 stop16h 56m

$965

Santa AnaSantiago

SNA - SCL

SNASCL

Santa Ana J. Wayne/Orange Cnty

Fri 9/26

9:20 pm-6:59 am

2 stops29h 39m

Santiago Arturo Merino Benitez

Sat 10/4

10:55 pm-8:27 pm

2 stops25h 32m

$1,117

Santa AnaSantiago

SNA - SCL

SNASCL

Santa Ana J. Wayne/Orange Cnty

Fri 9/26

9:20 pm-7:00 am

1 stop29h 40m

Santiago Arturo Merino Benitez

Sat 10/4

10:55 pm-8:27 pm

2 stops25h 32m

$1,123

Santa AnaSantiago

SNA - SCL

SNASCL

Santa Ana J. Wayne/Orange Cnty

Sun 12/21

10:52 am-12:15 pm

2 stops44h 23m

Santiago Arturo Merino Benitez

Mon 1/5

8:55 pm-11:25 am

2 stops43h 30m

$2,014

Santa AnaSantiago

SNA - SCL

SNASCL

Santa Ana J. Wayne/Orange Cnty

Sat 12/20

12:25 pm-12:15 pm

2 stops42h 50m

Santiago Arturo Merino Benitez

Mon 1/5

8:55 pm-11:25 am

2 stops43h 30m

$2,114

Flights are sorted by cheapest round-trip flights first.

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How to get the cheapest flight ticket from Santa Ana to Santiago

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to Santiago?

The cheapest day to depart on your flight to Santiago is on a Monday when prices can be found for as low as $844. This is often the case because there is less demand to fly during this day of the week. Be sure to avoid booking your departure on a Saturday as prices are generally higher than usual. According to our data, the average ticket price to Santiago on Saturday is $1,048.

What is the cheapest time of day to depart on your flight to Santiago?

In the morning is the cheapest time of day to fly from Santa Ana to Santiago when you can find flight prices for as low as $850. Flying to Santiago in the morning is an ideal time because this is during off-peak travel hours. In the evening is when there is more demand to fly to Santiago, so prices are often more expensive at around $1,020 per ticket.

When to book flights from Santa Ana to Santiago

Are you open to changing your travel dates? Check out the ideal times to fly from Santa Ana to Santiago according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Santa Ana to Santiago (SNA to SCL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Santa Ana to Santiago

Direct flights

None
There are no direct flights from Santa Ana to Santiago. There are no popular flight routes from Santa Ana to Santiago.
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  • How far is Santa Ana J. Wayne/Orange Cnty to Santiago Arturo Merino Benitez by plane?

    A flight from Santa Ana J. Wayne/Orange Cnty to Santiago Arturo Merino Benitez will travel around 5557.9 mi. By plane, this route typically takes 14h 25m.

  • When did momondo last update prices for flights from Santa Ana J. Wayne/Orange Cnty Airport to Santiago Arturo Merino Benitez Airport?

    Prices for flights from Santa Ana J. Wayne/Orange Cnty Airport to Santiago Arturo Merino Benitez Airport are refreshed on a daily basis.

  • How old do you have to be to fly from Santa Ana J. Wayne/Orange Cnty Airport to Santiago Arturo Merino Benitez Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Santa Ana J. Wayne/Orange Cnty Airport to Santiago Arturo Merino Benitez Airport.

  • What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?

    The travel and health documents required for your trip to Santiago Arturo Merino Benitez Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Santiago Arturo Merino Benitez Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Traveling to a place near Santiago?

Book flights to Santiago if you plan to visit one of these locations
Viña del Mar
Santa Cruz
Valparaíso
Valle Nevado
San Fernando
Pichilemu

Why use momondo?

Why should I use momondo to find a flight deal from Santa Ana to Santiago?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Santa Ana to Santiago for you.

Can I find flights from Santa Ana to Santiago with flexible booking policies on momondo?

momondo does allow users to show only those flights to Santiago from Santa Ana which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Santa Ana to Santiago?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Santiago from Santa Ana.

I’m not ready to book a flight from Santa Ana to Santiago right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Santiago, momondo offers a useful price alert feature which will track prices for flights to Santiago from Santa Ana and alert you when they change.

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