Cheap flights from San Francisco to Cairo from $324

In general, February is the cheapest month to fly from San Francisco to Cairo. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $762. If you’re not able to fly to Cairo in February, then April is your next best option. Flight prices from San Francisco to Cairo during April average around $778.

You are more likely to see cheaper flights to Cairo from San Francisco when booking weeks ahead of your departure date. In general, you can expect to find flights to Cairo for around $1,025 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Cairo from San Francisco for as low as $966 on momondo.

You could potentially save up to 21% on your flight if you consider stops on a San Francisco to Cairo flight.

As of October 2026, prices for San Francisco to Cairo flights are approximately 21% more expensive when compared to flights at the same time last year.

SAUDIA and Delta are the most popular carriers operating from San Francisco to Cairo

Turkish Airlines, ITA Airways and Delta are the top three most popular airlines that fly to Cairo from San Francisco according to our data. Turkish Airlines is the first choice among our users, with 49% of people opting to fly with this airline when traveling to Cairo. Keep in mind that there are 16 different airlines that fly to Cairo on a routine basis, so you have a few additional options to choose from.

Istanbul (IST) was the most common stop: 43% of momondo users choosing 1-stop flights on this route connected there.

Flights via Rome (FCO) offer the lowest average round-trip price of $826.

Flights connecting via Frankfurt am Main (FRA) have the shortest average one-way travel time: 20h 01m.

Dubai (DXB) has the shortest average layover time for this route: 2h 14m.