Which layover airport has the shortest travel time from San Diego to Santiago?

Flights connecting via Atlanta (ATL) have the shortest average one-way travel time: 15h 05m.

Which layover airport offers the lowest fares from San Diego to Santiago?

Flights via Panama City (PTY) offer the lowest average round-trip price of $543.

What is the cheapest airline that flies from San Diego to Santiago Arturo Merino Benitez?

LATAM Airlines and American Airlines are the most popular carriers operating from San Diego to Santiago Arturo Merino Benitez

What airlines fly to Santiago?

LATAM Airlines, American Airlines and Delta are the top three most popular airlines that fly to Santiago from San Diego according to our data. LATAM Airlines is the first choice among our users, with 38% of people opting to fly with this airline when traveling to Santiago. Keep in mind that there are 5 different airlines that fly to Santiago on a routine basis, so you have a few additional options to choose from.

Which layover airport has the shortest connection time from San Diego to Santiago?

Atlanta (ATL) has the shortest average layover time for this route: 1h 52m.

Which airport is the most popular layover for flights between San Diego and Santiago?

Panama City (PTY) was the most common stop: 40% of momondo users choosing 1-stop flights on this route connected there.

When did momondo last update prices for flights from San Diego Airport to Santiago Arturo Merino Benitez Airport?

Prices for flights from San Diego Airport to Santiago Arturo Merino Benitez Airport are refreshed on a daily basis.

How many operators does momondo search for flights from San Diego Airport to Santiago Arturo Merino Benitez Airport?

There are 5 operators available for flights from San Diego Airport to Santiago Arturo Merino Benitez Airport as of February 2026.

How old do you have to be to fly from San Diego Airport to Santiago Arturo Merino Benitez Airport?

The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from San Diego Airport to Santiago Arturo Merino Benitez Airport.

What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?

The required travel and health documents for your Santiago Arturo Merino Benitez Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Santiago Arturo Merino Benitez Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

$331 Cheap Flights from San Diego to Santiago in 2026

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Find the cheapest flights from San Diego to Santiago

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One-way

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10:30 pm - 7:40 am

SAN

SCL

29h 10m

1 stop

6:40 pm - 12:58 pm

SCL

SAN

22h 18m

2 stops

$653LATAM Airlines

Mon, Mar 16 - Wed, Mar 18

1:01 pm - 9:05 am

SAN

SCL

16h 04m

1 stop

8:35 pm - 11:53 am

SCL

SAN

18h 18m

1 stop

$704American Airlines

Wed, Mar 25 - Mon, Apr 27

9:53 am - 7:00 am

SAN

SCL

17h 07m

2 stops

8:35 pm - 3:51 pm

SCL

SAN

22h 16m

2 stops

$709American Airlines

Wed, Mar 25 - Mon, Apr 27

12:36 pm - 6:50 am

SAN

SCL

15h 14m

1 stop

8:30 pm - 11:36 am

SCL

SAN

18h 06m

1 stop

$719American Airlines

Thu, Jun 11 - Thu, Jul 9

6:20 am - 6:50 am

SAN

SCL

21h 30m

2 stops

8:30 pm - 11:36 am

SCL

SAN

18h 06m

1 stop

$724American Airlines

Thu, Jun 11 - Thu, Jul 9

3:15 pm - 2:05 pm

SAN

SCL

19h 50m

2 stops

4:00 pm - 6:39 pm

SCL

SAN

29h 39m

2 stops

$745LATAM Airlines

Mon, Apr 20 - Thu, Apr 23

6:20 am - 1:05 pm

SAN

SCL

27h 45m

3 stops

4:00 pm - 6:39 pm

SCL

SAN

29h 39m

2 stops

$750LATAM Airlines

Mon, Apr 20 - Thu, Apr 23

12:40 pm - 11:15 am

SAN

SCL

18h 35m

1 stop

10:25 pm - 6:51 pm

SCL

SAN

24h 26m

1 stop

$752Multiple Airlines

Mon, Mar 16 - Thu, Mar 19

12:36 pm - 6:50 am

SAN

SCL

15h 14m

1 stop

8:30 pm - 11:14 am

SCL

SAN

17h 44m

1 stop

$769American Airlines

Mon, Jul 27 - Thu, Aug 13

10:40 am - 5:35 am

SAN

SCL

15h 55m

1 stop

11:05 pm - 6:39 pm

SCL

SAN

22h 34m

2 stops

$772LATAM Airlines

Mon, Apr 6 - Mon, Apr 13

Delta flights from San Diego to Santiago

Our best Delta deals on San Diego to Santiago flight tickets

Delta

Jun 6

SAN6:15 amSan Diego

20h 20m

1 stop

SCL5:35 amSantiago Arturo Merino Benitez

Jun 28

SCL10:55 pmSantiago Arturo Merino Benitez

24h 53m

1 stop

SAN8:48 pmSan Diego

$816

Delta

Mar 30

SAN7:00 amSan Diego

20h 25m

1 stop

SCL7:25 amSantiago Arturo Merino Benitez

Apr 2

SCL8:55 pmSantiago Arturo Merino Benitez

20h 03m

2 stops

SAN12:58 pmSan Diego

$907

Delta

Mar 30

SAN10:30 pmSan Diego

27h 05m

2 stops

SCL5:35 amSantiago Arturo Merino Benitez

Apr 2

SCL8:55 pmSantiago Arturo Merino Benitez

20h 03m

2 stops

SAN12:58 pmSan Diego

$912

LATAM Airlines flights from San Diego to Santiago

Our best LATAM Airlines deals on San Diego to Santiago flight tickets

LATAM Airlines

Mar 16

SAN10:30 pmSan Diego

29h 10m

1 stop

SCL7:40 amSantiago Arturo Merino Benitez

Mar 18

SCL6:40 pmSantiago Arturo Merino Benitez

22h 18m

2 stops

SAN12:58 pmSan Diego

$653

LATAM Airlines

Apr 20

SAN3:15 pmSan Diego

19h 50m

2 stops

SCL2:05 pmSantiago Arturo Merino Benitez

Apr 23

SCL4:00 pmSantiago Arturo Merino Benitez

29h 39m

2 stops

SAN6:39 pmSan Diego

$745

LATAM Airlines

Apr 20

SAN6:20 amSan Diego

27h 45m

3 stops

SCL1:05 pmSantiago Arturo Merino Benitez

Apr 23

SCL4:00 pmSantiago Arturo Merino Benitez

29h 39m

2 stops

SAN6:39 pmSan Diego

$750

Fly from

Fly to

Route

Depart

Return

Price

San DiegoSantiago

SAN - SCL

SANSCL

San Diego

Mon 3/16

10:30 pm-7:40 am

1 stop29h 10m

Santiago Arturo Merino Benitez

Wed 3/18

6:40 pm-12:58 pm

2 stops22h 18m

$653

San DiegoSantiago

SAN - SCL

SANSCL

San Diego

Wed 3/25

1:01 pm-9:05 am

1 stop16h 04m

Santiago Arturo Merino Benitez

Mon 4/27

8:35 pm-11:53 am

1 stop18h 18m

$704

San DiegoSantiago

SAN - SCL

SANSCL

San Diego

Wed 3/25

9:53 am-7:00 am

2 stops17h 07m

Santiago Arturo Merino Benitez

Mon 4/27

8:35 pm-3:51 pm

2 stops22h 16m

$709

San DiegoSantiago

SAN - SCL

SANSCL

San Diego

Thu 6/11

12:36 pm-6:50 am

1 stop15h 14m

Santiago Arturo Merino Benitez

Thu 7/9

8:30 pm-11:36 am

1 stop18h 06m

$719

San DiegoSantiago

SAN - SCL

SANSCL

San Diego

Thu 6/11

6:20 am-6:50 am

2 stops21h 30m

Santiago Arturo Merino Benitez

Thu 7/9

8:30 pm-11:36 am

1 stop18h 06m

$724

San DiegoSantiago

SAN - SCL

SANSCL

San Diego

Mon 4/20

3:15 pm-2:05 pm

2 stops19h 50m

Santiago Arturo Merino Benitez

Thu 4/23

4:00 pm-6:39 pm

2 stops29h 39m

$745

San DiegoSantiago

SAN - SCL

SANSCL

San Diego

Mon 4/20

6:20 am-1:05 pm

3 stops27h 45m

Santiago Arturo Merino Benitez

Thu 4/23

4:00 pm-6:39 pm

2 stops29h 39m

$750

San DiegoSantiago

SAN - SCL

SANSCL

San Diego

Mon 3/16

12:40 pm-11:15 am

1 stop18h 35m

Santiago Arturo Merino Benitez

Thu 3/19

10:25 pm-6:51 pm

1 stop24h 26m

$752

San DiegoSantiago

SAN - SCL

SANSCL

San Diego

Mon 7/27

12:36 pm-6:50 am

1 stop15h 14m

Santiago Arturo Merino Benitez

Thu 8/13

8:30 pm-11:14 am

1 stop17h 44m

$769

San DiegoSantiago

SAN - SCL

SANSCL

San Diego

Mon 4/6

10:40 am-5:35 am

1 stop15h 55m

Santiago Arturo Merino Benitez

Mon 4/13

11:05 pm-6:39 pm

2 stops22h 34m

$772

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How to get the cheapest flight ticket from San Diego to Santiago

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Layovers

What is the cheapest month to fly to Santiago?

In general, November is the cheapest month to fly from San Diego to Santiago. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $635. If you don’t want to visit Santiago in November, then you should wait until August to fly from San Diego, when ticket prices are also cheap, with an average price of $654.

How far in advance should I book a flight to Santiago?

You are more likely to see cheaper flights to Santiago from San Diego when booking weeks ahead of your departure date. In general, you can expect to find flights to Santiago for around $929 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Santiago from San Diego for as low as $453 on momondo.

How have San Diego to Santiago flight prices changed over time?

When to book flights from San Diego to Santiago

Are you open to changing your travel dates? Check out the ideal times to fly from San Diego to Santiago according to our flight data. Find out which month and days have the cheapest flights.

Estimated round-trip price

Cheap San Diego to Santiago (SAN to SCL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from San Diego to Santiago

Fastest flight time	19h 50m
Direct flights	None

The fastest flight from San Diego to Santiago takes 19h 50m

There are no direct flights from San Diego to Santiago. There are no popular flight routes from San Diego to Santiago.

Search flight deals

How far is San Diego to Santiago Arturo Merino Benitez by plane?
There are 5476.6 mi between San Diego and Santiago Arturo Merino Benitez. In terms of flight time, this usually takes a little over 19h 50m.
When did momondo last update prices for flights from San Diego Airport to Santiago Arturo Merino Benitez Airport?
Prices for flights from San Diego Airport to Santiago Arturo Merino Benitez Airport are refreshed on a daily basis.
How many operators does momondo search for flights from San Diego Airport to Santiago Arturo Merino Benitez Airport?
There are 5 operators available for flights from San Diego Airport to Santiago Arturo Merino Benitez Airport as of February 2026.
How old do you have to be to fly from San Diego Airport to Santiago Arturo Merino Benitez Airport?
The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from San Diego Airport to Santiago Arturo Merino Benitez Airport.
What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?
The required travel and health documents for your Santiago Arturo Merino Benitez Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Santiago Arturo Merino Benitez Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.
What is the most popular airline from San Diego to Santiago?
Based on momondo bookings for this flight route, the most popular airline on flight routes from San Diego to Santiago is LATAM Airlines (35% of total bookings). The next most popular airlines are American Airlines (27%), Delta (19%), and United Airlines (11%).

Best airlines flying from San Diego to Santiago

Compare and see reviews for airlines that fly from San Diego to Santiago with momondo

Airline	Rating	Free Cancellation	Price
Copa Airlines	PriceFrom $453	Free Cancellation	Rating 7.5 1,557 reviews	Search Copa Airlines flights
LATAM Airlines	PriceFrom $507	Free Cancellation	Rating 7.5 1,924 reviews	Search LATAM Airlines flights
American Airlines	PriceFrom $563	Free Cancellation	Rating 7.1 11,367 reviews	Search American Airlines flights
United Airlines	PriceFrom $574	Free Cancellation	Rating 7.4 9,362 reviews	Search United Airlines flights
Delta	PriceFrom $642	Free Cancellation	Rating 7.9 8,245 reviews	Search Delta flights

Viña del Mar

Valparaíso

Santa Cruz

Valle Nevado

San Fernando

Pichilemu

Zapallar

Why use momondo?

Why should I use momondo to find a flight deal from San Diego to Santiago?

It is quick and easy to find San Diego to Santiago flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Santiago that suits you.

Can I find flights from San Diego to Santiago with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for San Diego to Santiago flights to just show those with flexible booking policies.

How can momondo help me find flights from San Diego to Santiago?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from San Diego to Santiago.

I’m not ready to book a flight from San Diego to Santiago right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Santiago, momondo offers a useful price alert feature which will track prices for flights to Santiago from San Diego and alert you when they change.