Which layover airport offers the lowest fares from San Diego to Santiago?

Flights via Panama City (PTY) offer the lowest average round-trip price of $550.

Which airport is the most popular layover for flights between San Diego and Santiago?

Panama City (PTY) was the most common stop: 50% of momondo users choosing 1-stop flights on this route connected there.

What is the cheapest airline that flies from San Diego to Santiago Arturo Merino Benitez?

LATAM Airlines is the most popular carrier operating from San Diego to Santiago Arturo Merino Benitez

What airlines fly to Santiago?

American Airlines, LATAM Airlines and United Airlines are the top three most popular airlines that fly to Santiago from San Diego according to our data. American Airlines is the first choice among our users, with 37% of people opting to fly with this airline when traveling to Santiago. Keep in mind that there are 5 different airlines that fly to Santiago on a routine basis, so you have a few additional options to choose from.

Which layover airport has the shortest connection time from San Diego to Santiago?

Atlanta (ATL) has the shortest average layover time for this route: 1h 28m.

Which layover airport has the shortest travel time from San Diego to Santiago?

Flights connecting via Atlanta (ATL) have the shortest average one-way travel time: 14h 10m.

When did momondo last update prices for flights from San Diego Airport to Santiago Arturo Merino Benitez Airport?

Prices for flights from San Diego Airport to Santiago Arturo Merino Benitez Airport are refreshed on a daily basis.

How many operators does momondo search for flights from San Diego Airport to Santiago Arturo Merino Benitez Airport?

There are 5 operators available for flights from San Diego Airport to Santiago Arturo Merino Benitez Airport as of May 2026.

How old do you have to be to fly from San Diego Airport to Santiago Arturo Merino Benitez Airport?

The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from San Diego Airport to Santiago Arturo Merino Benitez Airport.

What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?

The required travel and health documents for your Santiago Arturo Merino Benitez Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Santiago Arturo Merino Benitez Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

$365 Cheap Flights from San Diego to Santiago in 2026

Q: What is the typical price of a round-trip flight between San Diego and Santiago?

Prices are currently low for flights on this route. Typical prices usually range from $892 to $745. The lowest price recently found on this route was $706.

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Find the cheapest flights from San Diego to Santiago

Round-trip

One-way

Last minute

Cheap round-trip flights

Enter your travel dates to find the best prices.

8:58 pm - 7:36 pm

SAN

SCL

19h 38m

1 stop

4:14 am - 6:30 pm

SCL

SAN

17h 16m

1 stop

$706Copa Airlines

Fri, Aug 14 - Fri, Aug 21

10:00 pm - 1:50 am

SAN

SCL

24h 50m

1 stop

4:21 am - 6:30 pm

SCL

SAN

17h 09m

1 stop

$729Copa Airlines

Thu, Jul 9 - Thu, Jul 23

6:20 am - 1:25 pm

SAN

SCL

26h 05m

2 stops

11:10 pm - 10:10 am

SCL

SAN

16h 00m

1 stop

$749LATAM Airlines

Thu, Nov 5 - Sun, Nov 15

10:30 pm - 7:15 am

SAN

SCL

29h 45m

1 stop

8:40 pm - 9:26 am

SCL

SAN

15h 46m

1 stop

$750LATAM Airlines

Sun, Jul 12 - Sun, Jul 19

6:15 am - 5:35 am

SAN

SCL

20h 20m

1 stop

8:40 pm - 11:07 am

SCL

SAN

17h 27m

1 stop

$757LATAM Airlines

Tue, Aug 18 - Tue, Aug 25

12:32 pm - 7:15 am

SAN

SCL

15h 43m

1 stop

6:45 pm - 11:07 am

SCL

SAN

19h 22m

2 stops

$770LATAM Airlines

Tue, Aug 18 - Tue, Aug 25

10:55 am - 5:25 pm

SAN

SCL

27h 30m

2 stops

6:45 pm - 11:07 am

SCL

SAN

19h 22m

2 stops

$784LATAM Airlines

Tue, Aug 18 - Tue, Aug 25

10:00 am - 5:35 am

SAN

SCL

14h 35m

1 stop

5:40 am - 10:55 pm

SCL

SAN

22h 15m

2 stops

$803LATAM Airlines

Thu, Nov 5 - Wed, Nov 18

10:00 am - 5:35 am

SAN

SCL

14h 35m

1 stop

11:25 pm - 10:30 am

SCL

SAN

16h 05m

1 stop

$804LATAM Airlines

Thu, Nov 5 - Wed, Nov 18

10:55 am - 5:35 am

SAN

SCL

15h 40m

1 stop

11:25 pm - 7:16 pm

SCL

SAN

23h 51m

1 stop

$817LATAM Airlines

Fri, Sep 4 - Sat, Sep 26

LATAM Airlines flights from San Diego to Santiago

Our best LATAM Airlines deals on San Diego to Santiago flight tickets

LATAM Airlines

Nov 5

SAN6:20 amSan Diego

26h 05m

2 stops

SCL1:25 pmSantiago Arturo Merino Benitez

Nov 15

SCL11:10 pmSantiago Arturo Merino Benitez

16h 00m

1 stop

SAN10:10 amSan Diego

$749

LATAM Airlines

Jul 12

SAN10:30 pmSan Diego

29h 45m

1 stop

SCL7:15 amSantiago Arturo Merino Benitez

Jul 19

SCL8:40 pmSantiago Arturo Merino Benitez

15h 46m

1 stop

SAN9:26 amSan Diego

$750

LATAM Airlines

Aug 18

SAN6:15 amSan Diego

20h 20m

1 stop

SCL5:35 amSantiago Arturo Merino Benitez

Aug 25

SCL8:40 pmSantiago Arturo Merino Benitez

17h 27m

1 stop

SAN11:07 amSan Diego

$757

Copa Airlines flights from San Diego to Santiago

Our best Copa Airlines deals on San Diego to Santiago flight tickets

Copa Airlines

Aug 14

SAN8:58 pmSan Diego

19h 38m

1 stop

SCL7:36 pmSantiago Arturo Merino Benitez

Aug 21

SCL4:14 amSantiago Arturo Merino Benitez

17h 16m

1 stop

SAN6:30 pmSan Diego

$706

Copa Airlines

Jul 9

SAN10:00 pmSan Diego

24h 50m

1 stop

SCL1:50 amSantiago Arturo Merino Benitez

Jul 23

SCL4:21 amSantiago Arturo Merino Benitez

17h 09m

1 stop

SAN6:30 pmSan Diego

$729

Copa Airlines

Sep 28

SAN9:03 pmSan Diego

22h 36m

1 stop

SCL11:39 pmSantiago Arturo Merino Benitez

Oct 6

SCL3:15 amSantiago Arturo Merino Benitez

19h 15m

1 stop

SAN6:30 pmSan Diego

$883

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

San DiegoSantiago

SAN - SCL

SANSCL

San Diego

Fri 8/14

8:58 pm-7:36 pm

1 stop19h 38m

Santiago Arturo Merino Benitez

Fri 8/21

4:14 am-6:30 pm

1 stop17h 16m

$706

San DiegoSantiago

SAN - SCL

SANSCL

San Diego

Thu 7/9

10:00 pm-1:50 am

1 stop24h 50m

Santiago Arturo Merino Benitez

Thu 7/23

4:21 am-6:30 pm

1 stop17h 09m

$729

San DiegoSantiago

SAN - SCL

SANSCL

San Diego

Thu 11/5

6:20 am-1:25 pm

2 stops26h 05m

Santiago Arturo Merino Benitez

Sun 11/15

11:10 pm-10:10 am

1 stop16h 00m

$749

San DiegoSantiago

SAN - SCL

SANSCL

San Diego

Sun 7/12

10:30 pm-7:15 am

1 stop29h 45m

Santiago Arturo Merino Benitez

Sun 7/19

8:40 pm-9:26 am

1 stop15h 46m

$750

San DiegoSantiago

SAN - SCL

SANSCL

San Diego

Tue 8/18

6:15 am-5:35 am

1 stop20h 20m

Santiago Arturo Merino Benitez

Tue 8/25

8:40 pm-11:07 am

1 stop17h 27m

$757

San DiegoSantiago

SAN - SCL

SANSCL

San Diego

Tue 8/18

12:32 pm-7:15 am

1 stop15h 43m

Santiago Arturo Merino Benitez

Tue 8/25

6:45 pm-11:07 am

2 stops19h 22m

$770

San DiegoSantiago

SAN - SCL

SANSCL

San Diego

Tue 8/18

10:55 am-5:25 pm

2 stops27h 30m

Santiago Arturo Merino Benitez

Tue 8/25

6:45 pm-11:07 am

2 stops19h 22m

$784

San DiegoSantiago

SAN - SCL

SANSCL

San Diego

Thu 11/5

10:00 am-5:35 am

1 stop14h 35m

Santiago Arturo Merino Benitez

Wed 11/18

5:40 am-10:55 pm

2 stops22h 15m

$803

Quickest round-trip

San DiegoSantiago

SAN - SCL

SANSCL

San Diego

Thu 11/5

10:00 am-5:35 am

1 stop14h 35m

Santiago Arturo Merino Benitez

Wed 11/18

11:25 pm-10:30 am

1 stop16h 05m

$804

San DiegoSantiago

SAN - SCL

SANSCL

San Diego

Fri 9/4

10:55 am-5:35 am

1 stop15h 40m

Santiago Arturo Merino Benitez

Sat 9/26

11:25 pm-7:16 pm

1 stop23h 51m

$817

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from San Diego to Santiago

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Layovers

What is the typical price of a round-trip flight between San Diego and Santiago?

What is the cheapest month to fly to Santiago?

In general, September is the cheapest month to fly from San Diego to Santiago. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $573. If you don’t want to visit Santiago in September, then you should wait until November to fly from San Diego, when ticket prices are also cheap, with an average price of $671.

How far in advance should I book a flight from San Diego to Santiago?

You are more likely to see cheaper flights to Santiago from San Diego when booking weeks ahead of your departure date. In general, you can expect to find flights to Santiago for around $885 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Santiago from San Diego for as low as $453 on momondo.

How have San Diego to Santiago flight prices changed over time?

When to book flights from San Diego to Santiago

Are you open to changing your travel dates? Check out the ideal times to fly from San Diego to Santiago according to our flight data. Find out which month and days have the cheapest flights.

Estimated round-trip price

Cheap San Diego to Santiago (SAN to SCL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from San Diego to Santiago

Fastest flight time	15h 40m
Direct flights	None

The fastest flight from San Diego to Santiago takes 15h 40m

There are no direct flights from San Diego to Santiago. There are no popular flight routes from San Diego to Santiago.

Search flight deals

Frequently asked questions about flying from San Diego to Santiago

How far is San Diego to Santiago Arturo Merino Benitez by plane?
There are 5476.6 mi between San Diego and Santiago Arturo Merino Benitez. In terms of flight time, this usually takes a little over 15h 40m.
When did momondo last update prices for flights from San Diego Airport to Santiago Arturo Merino Benitez Airport?
Prices for flights from San Diego Airport to Santiago Arturo Merino Benitez Airport are refreshed on a daily basis.
How many operators does momondo search for flights from San Diego Airport to Santiago Arturo Merino Benitez Airport?
There are 5 operators available for flights from San Diego Airport to Santiago Arturo Merino Benitez Airport as of May 2026.
How old do you have to be to fly from San Diego Airport to Santiago Arturo Merino Benitez Airport?
The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from San Diego Airport to Santiago Arturo Merino Benitez Airport.
What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?
The required travel and health documents for your Santiago Arturo Merino Benitez Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Santiago Arturo Merino Benitez Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.
What is the most popular airline from San Diego to Santiago?
Based on momondo bookings for this flight route, the most popular airline on flight routes from San Diego to Santiago is American Airlines (34% of total bookings). The next most popular airlines are LATAM Airlines (31%), United Airlines (15%), and Delta (12%).

Best airlines flying from San Diego to Santiago

Compare and see reviews for airlines that fly from San Diego to Santiago with momondo

Airline	Rating	Free Cancellation	Price
Copa Airlines	PriceFrom $453	Free Cancellation	Rating 7.6 1,573 reviews	Search Copa Airlines flights
LATAM Airlines	PriceFrom $504	Free Cancellation	Rating 7.4 1,920 reviews	Search LATAM Airlines flights
American Airlines	PriceFrom $563	Free Cancellation	Rating 7.1 11,640 reviews	Search American Airlines flights
Delta	PriceFrom $574	Free Cancellation	Rating 7.9 8,422 reviews	Search Delta flights
United Airlines	PriceFrom $574	Free Cancellation	Rating 7.4 9,757 reviews	Search United Airlines flights

Viña del Mar

Valparaíso

Santa Cruz

Valle Nevado

Pichilemu

San Fernando

Zapallar

Why use momondo?

Why should I use momondo to find a flight deal from San Diego to Santiago?

It is quick and easy to find San Diego to Santiago flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Santiago that suits you.

Can I find flights from San Diego to Santiago with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for San Diego to Santiago flights to just show those with flexible booking policies.

How can momondo help me find flights from San Diego to Santiago?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from San Diego to Santiago.

I’m not ready to book a flight from San Diego to Santiago right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Santiago, momondo offers a useful price alert feature which will track prices for flights to Santiago from San Diego and alert you when they change.