Latest deals
Insights
When to book
FAQs
Reviews
Price Alerts

Cheap flights from San Diego to Santiago from $308

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from San Diego to Santiago departing on 12/10. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

Discover deals from 900+ travel sites with momondo.

Save money when you book flights with momondo

Big names and deals

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Price Alerts

Not ready to book? to track prices.
Search flight deals

Find the cheapest flights from San Diego to Santiago

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
8:25 am - 8:00 amSAN-SCL
18h 35m1 stop
American Airlines Logo
11:15 pm - 2:32 pmSCL-SAN
20h 17m1 stop
$650American Airlines
Find Deal
Tue, Dec 2 - Sat, Dec 6
American Airlines Logo
10:09 am - 8:00 amSAN-SCL
16h 51m2 stops
American Airlines Logo
11:15 pm - 3:21 pmSCL-SAN
21h 06m2 stops
$655American Airlines
Find Deal
Tue, Dec 2 - Sat, Dec 6
United Airlines Logo
1:47 pm - 8:50 amSAN-SCL
14h 03m1 stop
United Airlines Logo
10:45 pm - 6:21 pmSCL-SAN
24h 36m1 stop
$664United Airlines
Find Deal
Tue, Nov 25 - Mon, Dec 1
LATAM Airlines Logo
10:30 pm - 6:10 amSAN-SCL
26h 40m1 stop
LATAM Airlines Logo
10:15 pm - 11:48 pmSCL-SAN
30h 33m2 stops
$668LATAM Airlines
Find Deal
Fri, Dec 26 - Mon, Jan 19
United Airlines Logo
6:45 am - 8:50 amSAN-SCL
21h 05m2 stops
United Airlines Logo
10:45 pm - 8:45 pmSCL-SAN
27h 00m2 stops
$669United Airlines
Find Deal
Tue, Nov 25 - Mon, Dec 1
American Airlines Logo
9:37 am - 8:55 amSAN-SCL
18h 18m2 stops
American Airlines Logo
10:30 pm - 11:57 amSCL-SAN
18h 27m2 stops
$673American Airlines
Find Deal
Sun, Dec 7 - Sun, Dec 14
Copa Airlines Logo
8:16 pm - 11:43 pmSAN-SCL
22h 27m1 stop
Copa Airlines Logo
3:34 am - 5:41 pmSCL-SAN
19h 07m1 stop
$678Copa Airlines
Find Deal
Tue, Jan 13 - Sun, Jan 25
LATAM Airlines Logo
6:15 am - 5:35 amSAN-SCL
19h 20m2 stops
LATAM Airlines Logo
4:15 am - 10:55 pmSCL-SAN
21h 40m2 stops
$691LATAM Airlines
Find Deal
Fri, Mar 13 - Tue, Apr 14
LATAM Airlines Logo
6:15 am - 5:35 amSAN-SCL
19h 20m1 stop
LATAM Airlines Logo
4:15 am - 10:55 pmSCL-SAN
21h 40m2 stops
$700LATAM Airlines
Find Deal
Fri, Mar 13 - Tue, Apr 14
LATAM Airlines Logo
6:35 am - 7:00 amSAN-SCL
19h 25m2 stops
LATAM Airlines Logo
7:15 am - 9:54 amSCL-SAN
31h 39m3 stops
$715LATAM Airlines
Find Deal
Tue, Nov 25 - Tue, Dec 2

American Airlines flights from San Diego to Santiago

Our best American Airlines deals on San Diego to Santiago flight tickets
American Airlines
Dec 2
SAN8:25 amSan Diego
18h 35m
1 stop
SCL8:00 amSantiago Arturo Merino Benitez
Dec 6
SCL11:15 pmSantiago Arturo Merino Benitez
20h 17m
1 stop
SAN2:32 pmSan Diego
$650
Find similar
American Airlines
Dec 2
SAN6:15 amSan Diego
20h 45m
1 stop
SCL8:00 amSantiago Arturo Merino Benitez
Dec 6
SCL11:15 pmSantiago Arturo Merino Benitez
21h 06m
2 stops
SAN3:21 pmSan Diego
$655
Find similar
American Airlines
Dec 7
SAN9:37 amSan Diego
18h 18m
2 stops
SCL8:55 amSantiago Arturo Merino Benitez
Dec 14
SCL10:30 pmSantiago Arturo Merino Benitez
18h 27m
2 stops
SAN11:57 amSan Diego
$673
Find similar

United Airlines flights from San Diego to Santiago

Our best United Airlines deals on San Diego to Santiago flight tickets
United Airlines
Nov 25
SAN1:47 pmSan Diego
14h 03m
1 stop
SCL8:50 amSantiago Arturo Merino Benitez
Dec 1
SCL10:45 pmSantiago Arturo Merino Benitez
24h 36m
1 stop
SAN6:21 pmSan Diego
$664
Find similar
United Airlines
Nov 25
SAN6:45 amSan Diego
21h 05m
2 stops
SCL8:50 amSantiago Arturo Merino Benitez
Dec 2
SCL10:45 pmSantiago Arturo Merino Benitez
19h 05m
2 stops
SAN12:50 pmSan Diego
$669
Find similar
United Airlines
Nov 21
SAN5:50 pmSan Diego
34h 00m
1 stop
SCL8:50 amSantiago Arturo Merino Benitez
Dec 1
SCL10:45 pmSantiago Arturo Merino Benitez
22h 31m
1 stop
SAN4:16 pmSan Diego
$674
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from San Diego to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated November 13, 2025.
Use the filters below to find and compare flights from San Diego to Santiago that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

San DiegoSantiago

SAN - SCL

SANSCL

San Diego

Tue 12/2

8:25 am-8:00 am

1 stop18h 35m

Santiago Arturo Merino Benitez

Sat 12/6

11:15 pm-2:32 pm

1 stop20h 17m

$650

San DiegoSantiago

SAN - SCL

SANSCL

San Diego

Tue 12/2

10:09 am-8:00 am

2 stops16h 51m

Santiago Arturo Merino Benitez

Sat 12/6

11:15 pm-3:21 pm

2 stops21h 06m

$655

San DiegoSantiago

SAN - SCL

SANSCL

San Diego

Tue 11/25

1:47 pm-8:50 am

1 stop14h 03m

Santiago Arturo Merino Benitez

Mon 12/1

10:45 pm-6:21 pm

1 stop24h 36m

$664

San DiegoSantiago

SAN - SCL

SANSCL

San Diego

Fri 12/26

10:30 pm-6:10 am

1 stop26h 40m

Santiago Arturo Merino Benitez

Mon 1/19

10:15 pm-11:48 pm

2 stops30h 33m

$668

San DiegoSantiago

SAN - SCL

SANSCL

San Diego

Tue 11/25

6:45 am-8:50 am

2 stops21h 05m

Santiago Arturo Merino Benitez

Mon 12/1

10:45 pm-8:45 pm

2 stops27h 00m

$669

San DiegoSantiago

SAN - SCL

SANSCL

San Diego

Sun 12/7

9:37 am-8:55 am

2 stops18h 18m

Santiago Arturo Merino Benitez

Sun 12/14

10:30 pm-11:57 am

2 stops18h 27m

$673

San DiegoSantiago

SAN - SCL

SANSCL

San Diego

Tue 1/13

8:16 pm-11:43 pm

1 stop22h 27m

Santiago Arturo Merino Benitez

Sun 1/25

3:34 am-5:41 pm

1 stop19h 07m

$678

San DiegoSantiago

SAN - SCL

SANSCL

San Diego

Fri 3/13

6:15 am-5:35 am

2 stops19h 20m

Santiago Arturo Merino Benitez

Tue 4/14

4:15 am-10:55 pm

2 stops21h 40m

$691

San DiegoSantiago

SAN - SCL

SANSCL

San Diego

Fri 3/13

6:15 am-5:35 am

1 stop19h 20m

Santiago Arturo Merino Benitez

Tue 4/14

4:15 am-10:55 pm

2 stops21h 40m

$700

San DiegoSantiago

SAN - SCL

SANSCL

San Diego

Tue 11/25

6:35 am-7:00 am

2 stops19h 25m

Santiago Arturo Merino Benitez

Tue 12/2

7:15 am-9:54 am

3 stops31h 39m

$715

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
1
2

See travel insights to Santiago from

How to get the cheapest flight ticket from San Diego to Santiago

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Santiago?

In general, August is the cheapest month to fly from San Diego to Santiago. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $654. If you don’t want to visit Santiago in August, then you should wait until October to fly from San Diego, when ticket prices are also cheap, with an average price of $683.

What is the cheapest day to depart on your flight to Santiago?

The cheapest day to depart on your flight to Santiago is on a Sunday when prices can be found for as low as $1,003. This is often the case because there is less demand to fly during this day of the week. Be sure to avoid booking your departure on a Tuesday as prices are generally higher than usual. According to our data, the average ticket price to Santiago on Tuesday is $1,131.

What is the cheapest time of day to depart on your flight to Santiago?

At noon is the cheapest time of day to fly from San Diego to Santiago when you can find flight prices for as low as $882. Flying to Santiago at noon is an ideal time because this is during off-peak travel hours. In the afternoon is when there is more demand to fly to Santiago, so prices are often more expensive at around $1,072 per ticket.

How far in advance should I book a flight to Santiago?

You are more likely to see cheaper flights to Santiago from San Diego when booking weeks ahead of your departure date. In general, you can expect to find flights to Santiago for around $950 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Santiago from San Diego for as low as $453 on momondo.

How have San Diego to Santiago flight prices changed over time?

As of November 2025, prices for San Diego to Santiago flights are approximately 42% cheaper when compared to flights at the same time last year.

When to book flights from San Diego to Santiago

Are you open to changing your travel dates? Check out the ideal times to fly from San Diego to Santiago according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap San Diego to Santiago (SAN to SCL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from San Diego to Santiago

Direct flights

None
There are no direct flights from San Diego to Santiago. There are no popular flight routes from San Diego to Santiago.
Search flight deals

  • How far is San Diego to Santiago Arturo Merino Benitez by plane?

    There are 5476.6 mi between San Diego and Santiago Arturo Merino Benitez. In terms of flight time, this usually takes a little over 14h 03m.

  • When did momondo last update prices for flights from San Diego Airport to Santiago Arturo Merino Benitez Airport?

    Prices for flights from San Diego Airport to Santiago Arturo Merino Benitez Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from San Diego Airport to Santiago Arturo Merino Benitez Airport?

  • How old do you have to be to fly from San Diego Airport to Santiago Arturo Merino Benitez Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from San Diego Airport to Santiago Arturo Merino Benitez Airport.

  • What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?

    The required travel and health documents for your Santiago Arturo Merino Benitez Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Santiago Arturo Merino Benitez Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from San Diego to Santiago?

Best airlines flying from San Diego to Santiago

Compare and see reviews for airlines that fly from San Diego to Santiago with momondo
Airline
Rating
Free Cancellation
Price
Copa AirlinesPriceFrom $453Free CancellationRating
7.6
1,565 reviews
Search Copa Airlines flights
LATAM AirlinesPriceFrom $507Free CancellationRating
7.5
1,876 reviews
Search LATAM Airlines flights
American AirlinesPriceFrom $563Free CancellationRating
7.2
11,051 reviews
Search American Airlines flights
United AirlinesPriceFrom $574Free CancellationRating
7.4
9,017 reviews
Search United Airlines flights
DeltaPriceFrom $802Free CancellationRating
7.9
8,007 reviews
Search Delta flights

Traveling to a place near Santiago?

Book flights to Santiago if you plan to visit one of these locations
Viña del Mar
Santa Cruz
Valparaíso
Valle Nevado
San Fernando
Pichilemu

Why use momondo?

Why should I use momondo to find a flight deal from San Diego to Santiago?

It is quick and easy to find San Diego to Santiago flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Santiago that suits you.

Can I find flights from San Diego to Santiago with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for San Diego to Santiago flights to just show those with flexible booking policies.

How can momondo help me find flights from San Diego to Santiago?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from San Diego to Santiago.

I’m not ready to book a flight from San Diego to Santiago right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Santiago, momondo offers a useful price alert feature which will track prices for flights to Santiago from San Diego and alert you when they change.

An easier way to manage your Santiago trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
Start using Trips
Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.
1 adult
Sat 12/13
Sat 12/20
By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to Chile