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Cheap flights from San Diego to Santiago from $290

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from San Diego to Santiago departing on 11/8. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from San Diego to Santiago

Cheap round-trip flights

LATAM Airlines Logo
12:00 pm - 7:40 amSAN-SCL
14h 40m1 stop
LATAM Airlines Logo
8:10 am - 10:55 pmSCL-SAN
19h 45m2 stops
$488LATAM Airlines
Find Deal
Thu, Nov 6 - Fri, Nov 14
LATAM Airlines Logo
12:00 pm - 7:40 amSAN-SCL
14h 40m1 stop
LATAM Airlines Logo
11:55 pm - 9:19 amSCL-SAN
14h 24m1 stop
$498LATAM Airlines
Find Deal
Thu, Nov 6 - Fri, Nov 14
American Airlines Logo
12:30 pm - 8:00 amSAN-SCL
15h 30m1 stop
American Airlines Logo
9:55 pm - 11:26 amSCL-SAN
17h 31m1 stop
$514American Airlines
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Wed, Oct 8 - Wed, Oct 15
Delta Logo
2:00 pm - 1:20 pmSAN-SCL
19h 20m2 stops
Delta Logo
11:05 pm - 9:19 amSCL-SAN
14h 14m1 stop
$515Delta
Find Deal
Sun, Sep 14 - Sun, Sep 21
American Airlines Logo
12:30 pm - 8:00 amSAN-SCL
15h 30m1 stop
American Airlines Logo
9:55 pm - 3:30 pmSCL-SAN
21h 35m2 stops
$518American Airlines
Find Deal
Wed, Oct 8 - Wed, Oct 15
Delta Logo
6:20 am - 6:30 amSAN-SCL
20h 10m2 stops
Delta Logo
11:30 pm - 11:44 pmSCL-SAN
28h 14m2 stops
$519Delta
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Fri, Sep 12 - Sat, Sep 20
Copa Airlines Logo
9:08 pm - 10:40 pmSAN-SCL
22h 32m1 stop
Copa Airlines Logo
5:11 am - 5:50 pmSCL-SAN
16h 39m1 stop
$527Copa Airlines
Find Deal
Fri, Sep 5 - Wed, Sep 17
Copa Airlines Logo
9:12 pm - 11:40 pmSAN-SCL
22h 28m1 stop
Copa Airlines Logo
3:35 am - 5:57 pmSCL-SAN
18h 22m1 stop
$551Copa Airlines
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Fri, Oct 10 - Thu, Oct 16
United Airlines Logo
11:20 am - 8:50 amSAN-SCL
16h 30m2 stops
United Airlines Logo
10:45 pm - 2:55 pmSCL-SAN
21h 10m2 stops
$619United Airlines
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Fri, Nov 7 - Sat, Nov 22
United Airlines Logo
11:02 am - 8:50 amSAN-SCL
16h 48m2 stops
United Airlines Logo
10:45 pm - 1:04 pmSCL-SAN
19h 19m2 stops
$704United Airlines
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Fri, Nov 28 - Mon, Dec 8

Delta flights from San Diego to Santiago

Our best Delta deals on San Diego to Santiago flight tickets
Delta
Sep 14
SAN2:00 pmSan Diego
19h 20m
2 stops
SCL1:20 pmSantiago Arturo Merino Benitez
Sep 21
SCL11:05 pmSantiago Arturo Merino Benitez
14h 14m
1 stop
SAN9:19 amSan Diego
$515
Find similar
Delta
Sep 12
SAN6:20 amSan Diego
20h 10m
2 stops
SCL6:30 amSantiago Arturo Merino Benitez
Sep 20
SCL11:30 pmSantiago Arturo Merino Benitez
28h 14m
2 stops
SAN11:44 pmSan Diego
$519
Find similar
Delta
Sep 11
SAN9:52 pmSan Diego
29h 58m
1 stop
SCL7:50 amSantiago Arturo Merino Benitez
Sep 20
SCL11:30 pmSantiago Arturo Merino Benitez
28h 14m
2 stops
SAN11:44 pmSan Diego
$529
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LATAM Airlines flights from San Diego to Santiago

Our best LATAM Airlines deals on San Diego to Santiago flight tickets
LATAM Airlines
Nov 6
SAN12:00 pmSan Diego
14h 40m
1 stop
SCL7:40 amSantiago Arturo Merino Benitez
Nov 14
SCL8:10 amSantiago Arturo Merino Benitez
19h 45m
2 stops
SAN10:55 pmSan Diego
$488
Find similar
LATAM Airlines
Nov 6
SAN12:00 pmSan Diego
14h 40m
1 stop
SCL7:40 amSantiago Arturo Merino Benitez
Nov 14
SCL11:55 pmSantiago Arturo Merino Benitez
14h 24m
1 stop
SAN9:19 amSan Diego
$498
Find similar
LATAM Airlines
Nov 7
SAN6:15 amSan Diego
20h 25m
1 stop
SCL7:40 amSantiago Arturo Merino Benitez
Nov 22
SCL11:10 pmSantiago Arturo Merino Benitez
24h 01m
1 stop
SAN6:11 pmSan Diego
$508
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from San Diego to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 26, 2025.
Use the filters below to find and compare flights from San Diego to Santiago that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

San DiegoSantiago

SAN - SCL

SANSCL

San Diego

Thu 11/6

12:00 pm-7:40 am

1 stop14h 40m

Santiago Arturo Merino Benitez

Fri 11/14

8:10 am-10:55 pm

2 stops19h 45m

$488

San DiegoSantiago

SAN - SCL

SANSCL

San Diego

Thu 11/6

12:00 pm-7:40 am

1 stop14h 40m

Santiago Arturo Merino Benitez

Fri 11/14

11:55 pm-9:19 am

1 stop14h 24m

$498

San DiegoSantiago

SAN - SCL

SANSCL

San Diego

Wed 10/8

12:30 pm-8:00 am

1 stop15h 30m

Santiago Arturo Merino Benitez

Wed 10/15

9:55 pm-11:26 am

1 stop17h 31m

$514

San DiegoSantiago

SAN - SCL

SANSCL

San Diego

Sun 9/14

2:00 pm-1:20 pm

2 stops19h 20m

Santiago Arturo Merino Benitez

Sun 9/21

11:05 pm-9:19 am

1 stop14h 14m

$515

San DiegoSantiago

SAN - SCL

SANSCL

San Diego

Wed 10/8

12:30 pm-8:00 am

1 stop15h 30m

Santiago Arturo Merino Benitez

Wed 10/15

9:55 pm-3:30 pm

2 stops21h 35m

$518

San DiegoSantiago

SAN - SCL

SANSCL

San Diego

Fri 9/12

6:20 am-6:30 am

2 stops20h 10m

Santiago Arturo Merino Benitez

Sat 9/20

11:30 pm-11:44 pm

2 stops28h 14m

$519

San DiegoSantiago

SAN - SCL

SANSCL

San Diego

Fri 9/5

9:08 pm-10:40 pm

1 stop22h 32m

Santiago Arturo Merino Benitez

Wed 9/17

5:11 am-5:50 pm

1 stop16h 39m

$527

San DiegoSantiago

SAN - SCL

SANSCL

San Diego

Fri 10/10

9:12 pm-11:40 pm

1 stop22h 28m

Santiago Arturo Merino Benitez

Thu 10/16

3:35 am-5:57 pm

1 stop18h 22m

$551

San DiegoSantiago

SAN - SCL

SANSCL

San Diego

Fri 11/7

11:20 am-8:50 am

2 stops16h 30m

Santiago Arturo Merino Benitez

Sat 11/22

10:45 pm-2:55 pm

2 stops21h 10m

$619

San DiegoSantiago

SAN - SCL

SANSCL

San Diego

Fri 11/28

11:02 am-8:50 am

2 stops16h 48m

Santiago Arturo Merino Benitez

Mon 12/8

10:45 pm-1:04 pm

2 stops19h 19m

$704

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Santiago from

How to get the cheapest flight ticket from San Diego to Santiago

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Santiago?

In general, October is the cheapest month to fly from San Diego to Santiago. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $803. If you don’t want to visit Santiago in October, then you should wait until November to fly from San Diego, when ticket prices are also cheap, with an average price of $832.

What is the cheapest day to depart on your flight to Santiago?

The cheapest day to depart on your flight to Santiago is on a Sunday when prices can be found for as low as $1,003. This is often the case because there is less demand to fly during this day of the week. Be sure to avoid booking your departure on a Tuesday as prices are generally higher than usual. According to our data, the average ticket price to Santiago on Tuesday is $1,131.

What is the cheapest time of day to depart on your flight to Santiago?

At noon is the cheapest time of day to fly from San Diego to Santiago when you can find flight prices for as low as $882. Flying to Santiago at noon is an ideal time because this is during off-peak travel hours. In the afternoon is when there is more demand to fly to Santiago, so prices are often more expensive at around $1,072 per ticket.

How far in advance should I book a flight to Santiago?

You are more likely to see cheaper flights to Santiago from San Diego when booking weeks ahead of your departure date. In general, you can expect to find flights to Santiago for around $997 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Santiago from San Diego for as low as $758 on momondo.

How have San Diego to Santiago flight prices changed over time?

As of August 2025, prices for San Diego to Santiago flights are approximately 11% more expensive when compared to flights at the same time last year.

When to book flights from San Diego to Santiago

Are you open to changing your travel dates? Check out the ideal times to fly from San Diego to Santiago according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap San Diego to Santiago (SAN to SCL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from San Diego to Santiago

Direct flights

None
There are no direct flights from San Diego to Santiago. There are no popular flight routes from San Diego to Santiago.
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  • How far is San Diego to Santiago Arturo Merino Benitez by plane?

    There are 5476.6 mi between San Diego and Santiago Arturo Merino Benitez. In terms of flight time, this usually takes a little over 13h 57m.

  • When did momondo last update prices for flights from San Diego Airport to Santiago Arturo Merino Benitez Airport?

    Prices for flights from San Diego Airport to Santiago Arturo Merino Benitez Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from San Diego Airport to Santiago Arturo Merino Benitez Airport?

  • How old do you have to be to fly from San Diego Airport to Santiago Arturo Merino Benitez Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from San Diego Airport to Santiago Arturo Merino Benitez Airport.

  • What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?

    The required travel and health documents for your Santiago Arturo Merino Benitez Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Santiago Arturo Merino Benitez Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from San Diego to Santiago?

Best airlines flying from San Diego to Santiago

Compare and see reviews for airlines that fly from San Diego to Santiago with momondo
Airline
Rating
Free Cancellation
Price
Copa AirlinesPriceFrom $453Free CancellationRating
7.5
1,515 reviews
Search Copa Airlines flights
United AirlinesPriceFrom $542Free CancellationRating
7.4
8,943 reviews
Search United Airlines flights
LATAM AirlinesPriceFrom $632Free CancellationRating
7.5
1,843 reviews
Search LATAM Airlines flights
American AirlinesPriceFrom $693Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights
DeltaPriceFrom $792Free CancellationRating
7.9
7,979 reviews
Search Delta flights

Traveling to a place near Santiago?

Book flights to Santiago if you plan to visit one of these locations
Viña del Mar
Santa Cruz
Valparaíso
Valle Nevado
San Fernando
Pichilemu

Why use momondo?

Why should I use momondo to find a flight deal from San Diego to Santiago?

It is quick and easy to find San Diego to Santiago flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Santiago that suits you.

Can I find flights from San Diego to Santiago with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for San Diego to Santiago flights to just show those with flexible booking policies.

How can momondo help me find flights from San Diego to Santiago?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from San Diego to Santiago.

I’m not ready to book a flight from San Diego to Santiago right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Santiago, momondo offers a useful price alert feature which will track prices for flights to Santiago from San Diego and alert you when they change.

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