Which layover airport has the shortest connection time from San Diego to Santiago?

Atlanta (ATL) has the shortest average layover time for this route: 1h 28m.

What airlines fly to Santiago?

LATAM Airlines, American Airlines and Delta are the top three most popular airlines that fly to Santiago from San Diego according to our data. LATAM Airlines is the first choice among our users, with 37% of people opting to fly with this airline when traveling to Santiago. Keep in mind that there are 5 different airlines that fly to Santiago on a routine basis, so you have a few additional options to choose from.

Which airport is the most popular layover for flights between San Diego and Santiago?

Panama City (PTY) was the most common stop: 50% of momondo users choosing 1-stop flights on this route connected there.

Which layover airport offers the lowest fares from San Diego to Santiago?

Flights via Panama City (PTY) offer the lowest average round-trip price of $543.

What is the cheapest airline that flies from San Diego to Santiago Arturo Merino Benitez?

LATAM Airlines and Copa Airlines are the most popular carriers operating from San Diego to Santiago Arturo Merino Benitez

Which layover airport has the shortest travel time from San Diego to Santiago?

Flights connecting via Atlanta (ATL) have the shortest average one-way travel time: 14h 10m.

When did momondo last update prices for flights from San Diego Airport to Santiago Arturo Merino Benitez Airport?

Prices for flights from San Diego Airport to Santiago Arturo Merino Benitez Airport are refreshed on a daily basis.

How many operators does momondo search for flights from San Diego Airport to Santiago Arturo Merino Benitez Airport?

There are 5 operators available for flights from San Diego Airport to Santiago Arturo Merino Benitez Airport as of March 2026.

How old do you have to be to fly from San Diego Airport to Santiago Arturo Merino Benitez Airport?

The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from San Diego Airport to Santiago Arturo Merino Benitez Airport.

What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?

The required travel and health documents for your Santiago Arturo Merino Benitez Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Santiago Arturo Merino Benitez Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

$347 Cheap Flights from San Diego to Santiago in 2026

Q: What is the typical price of a round-trip flight between San Diego and Santiago?

Prices are currently low for flights on this route. Typical prices usually range from $1,103 to $888. The lowest price recently found on this route was $751.

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Find the cheapest flights from San Diego to Santiago

Round-trip

One-way

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Cheap round-trip flights

Enter your travel dates to find the best prices.

6:15 am - 4:50 am

SAN

SCL

19h 35m

2 stops

5:40 am - 10:55 pm

SCL

SAN

20h 15m

2 stops

$751LATAM Airlines

Tue, Aug 18 - Sat, Aug 29

6:20 am - 4:50 am

SAN

SCL

19h 30m

2 stops

11:25 pm - 6:03 pm

SCL

SAN

21h 38m

1 stop

$753LATAM Airlines

Tue, May 5 - Sun, May 17

9:18 pm - 11:26 pm

SAN

SCL

23h 08m

1 stop

11:25 am - 6:30 pm

SCL

SAN

34h 05m

1 stop

$757Copa Airlines

Fri, Apr 10 - Thu, Apr 23

9:18 pm - 7:23 pm

SAN

SCL

19h 05m

1 stop

12:09 am - 6:30 pm

SCL

SAN

21h 21m

1 stop

$760Copa Airlines

Mon, Apr 13 - Tue, Apr 21

9:12 am - 7:05 am

SAN

SCL

18h 53m

2 stops

8:35 pm - 11:53 am

SCL

SAN

18h 18m

1 stop

$765American Airlines

Fri, Apr 10 - Thu, Apr 23

6:15 am - 5:35 am

SAN

SCL

20h 20m

1 stop

5:40 am - 10:55 pm

SCL

SAN

20h 15m

2 stops

$769LATAM Airlines

Thu, Jun 4 - Sat, Aug 29

8:00 am - 7:15 am

SAN

SCL

20h 15m

1 stop

11:25 pm - 6:03 pm

SCL

SAN

21h 38m

1 stop

$771LATAM Airlines

Tue, May 5 - Sun, May 17

12:53 pm - 7:05 am

SAN

SCL

15h 12m

1 stop

8:35 pm - 11:16 am

SCL

SAN

17h 41m

1 stop

$772American Airlines

Tue, May 5 - Sun, May 17

12:53 pm - 7:05 am

SAN

SCL

15h 12m

1 stop

8:35 pm - 10:28 pm

SCL

SAN

28h 53m

1 stop

$774American Airlines

Sat, May 9 - Sun, May 17

10:53 am - 6:55 am

SAN

SCL

17h 02m

2 stops

11:25 pm - 2:57 pm

SCL

SAN

18h 32m

1 stop

$776LATAM Airlines

Thu, May 14 - Sun, May 17

Delta flights from San Diego to Santiago

Our best Delta deals on San Diego to Santiago flight tickets

Delta

May 25

SAN10:00 pmSan Diego

29h 50m

1 stop

SCL6:50 amSantiago Arturo Merino Benitez

May 30

SCL11:25 pmSantiago Arturo Merino Benitez

21h 38m

1 stop

SAN6:03 pmSan Diego

$794

Delta

May 7

SAN6:15 amSan Diego

20h 20m

1 stop

SCL5:35 amSantiago Arturo Merino Benitez

May 16

SCL11:25 pmSantiago Arturo Merino Benitez

18h 32m

1 stop

SAN2:57 pmSan Diego

$796

Delta

May 8

SAN8:00 amSan Diego

19h 55m

2 stops

SCL6:55 amSantiago Arturo Merino Benitez

May 18

SCL7:55 pmSantiago Arturo Merino Benitez

18h 21m

2 stops

SAN11:16 amSan Diego

$798

Copa Airlines flights from San Diego to Santiago

Our best Copa Airlines deals on San Diego to Santiago flight tickets

Copa Airlines

Apr 10

SAN9:18 pmSan Diego

23h 08m

1 stop

SCL11:26 pmSantiago Arturo Merino Benitez

Apr 23

SCL11:25 amSantiago Arturo Merino Benitez

34h 05m

1 stop

SAN6:30 pmSan Diego

$757

Copa Airlines

Apr 13

SAN9:18 pmSan Diego

19h 05m

1 stop

SCL7:23 pmSantiago Arturo Merino Benitez

Apr 21

SCL12:09 amSantiago Arturo Merino Benitez

21h 21m

1 stop

SAN6:30 pmSan Diego

$760

Copa Airlines

May 10

SAN10:00 pmSan Diego

18h 23m

1 stop

SCL7:23 pmSantiago Arturo Merino Benitez

May 16

SCL12:01 amSantiago Arturo Merino Benitez

21h 29m

1 stop

SAN6:30 pmSan Diego

$793

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

San DiegoSantiago

SAN - SCL

SANSCL

San Diego

Tue 8/18

6:15 am-4:50 am

2 stops19h 35m

Santiago Arturo Merino Benitez

Sat 8/29

5:40 am-10:55 pm

2 stops20h 15m

$751

San DiegoSantiago

SAN - SCL

SANSCL

San Diego

Tue 5/5

6:20 am-4:50 am

2 stops19h 30m

Santiago Arturo Merino Benitez

Sun 5/17

11:25 pm-6:03 pm

1 stop21h 38m

$753

San DiegoSantiago

SAN - SCL

SANSCL

San Diego

Fri 4/10

9:18 pm-11:26 pm

1 stop23h 08m

Santiago Arturo Merino Benitez

Thu 4/23

11:25 am-6:30 pm

1 stop34h 05m

$757

San DiegoSantiago

SAN - SCL

SANSCL

San Diego

Mon 4/13

9:18 pm-7:23 pm

1 stop19h 05m

Santiago Arturo Merino Benitez

Tue 4/21

12:09 am-6:30 pm

1 stop21h 21m

$760

San DiegoSantiago

SAN - SCL

SANSCL

San Diego

Fri 4/10

9:12 am-7:05 am

2 stops18h 53m

Santiago Arturo Merino Benitez

Thu 4/23

8:35 pm-11:53 am

1 stop18h 18m

$765

San DiegoSantiago

SAN - SCL

SANSCL

San Diego

Thu 6/4

6:15 am-5:35 am

1 stop20h 20m

Santiago Arturo Merino Benitez

Sat 8/29

5:40 am-10:55 pm

2 stops20h 15m

$769

San DiegoSantiago

SAN - SCL

SANSCL

San Diego

Tue 5/5

8:00 am-7:15 am

1 stop20h 15m

Santiago Arturo Merino Benitez

Sun 5/17

11:25 pm-6:03 pm

1 stop21h 38m

$771

Quickest round-trip

San DiegoSantiago

SAN - SCL

SANSCL

San Diego

Tue 5/5

12:53 pm-7:05 am

1 stop15h 12m

Santiago Arturo Merino Benitez

Sun 5/17

8:35 pm-11:16 am

1 stop17h 41m

$772

San DiegoSantiago

SAN - SCL

SANSCL

San Diego

Sat 5/9

12:53 pm-7:05 am

1 stop15h 12m

Santiago Arturo Merino Benitez

Sun 5/17

8:35 pm-10:28 pm

1 stop28h 53m

$774

San DiegoSantiago

SAN - SCL

SANSCL

San Diego

Thu 5/14

10:53 am-6:55 am

2 stops17h 02m

Santiago Arturo Merino Benitez

Sun 5/17

11:25 pm-2:57 pm

1 stop18h 32m

$776

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from San Diego to Santiago

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Layovers

What is the typical price of a round-trip flight between San Diego and Santiago?

What is the cheapest month to fly to Santiago?

In general, August is the cheapest month to fly from San Diego to Santiago. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $550. If you don’t want to visit Santiago in August, then you should wait until November to fly from San Diego, when ticket prices are also cheap, with an average price of $599.

How far in advance should I book a flight to Santiago?

You are more likely to see cheaper flights to Santiago from San Diego when booking weeks ahead of your departure date. In general, you can expect to find flights to Santiago for around $923 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Santiago from San Diego for as low as $453 on momondo.

How have San Diego to Santiago flight prices changed over time?

When to book flights from San Diego to Santiago

Are you open to changing your travel dates? Check out the ideal times to fly from San Diego to Santiago according to our flight data. Find out which month and days have the cheapest flights.

Estimated round-trip price

Cheap San Diego to Santiago (SAN to SCL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from San Diego to Santiago

Fastest flight time	15h 36m
Direct flights	None

The fastest flight from San Diego to Santiago takes 15h 36m

There are no direct flights from San Diego to Santiago. There are no popular flight routes from San Diego to Santiago.

Search flight deals

How far is San Diego to Santiago Arturo Merino Benitez by plane?
There are 5476.6 mi between San Diego and Santiago Arturo Merino Benitez. In terms of flight time, this usually takes a little over 15h 36m.
When did momondo last update prices for flights from San Diego Airport to Santiago Arturo Merino Benitez Airport?
Prices for flights from San Diego Airport to Santiago Arturo Merino Benitez Airport are refreshed on a daily basis.
How many operators does momondo search for flights from San Diego Airport to Santiago Arturo Merino Benitez Airport?
There are 5 operators available for flights from San Diego Airport to Santiago Arturo Merino Benitez Airport as of March 2026.
How old do you have to be to fly from San Diego Airport to Santiago Arturo Merino Benitez Airport?
The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from San Diego Airport to Santiago Arturo Merino Benitez Airport.
What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?
The required travel and health documents for your Santiago Arturo Merino Benitez Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Santiago Arturo Merino Benitez Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.
What is the most popular airline from San Diego to Santiago?
Based on momondo bookings for this flight route, the most popular airline on flight routes from San Diego to Santiago is LATAM Airlines (33% of total bookings). The next most popular airlines are American Airlines (30%), Delta (14%), and United Airlines (12%).

Best airlines flying from San Diego to Santiago

Compare and see reviews for airlines that fly from San Diego to Santiago with momondo

Airline	Rating	Free Cancellation	Price
Copa Airlines	PriceFrom $453	Free Cancellation	Rating 7.5 1,579 reviews	Search Copa Airlines flights
LATAM Airlines	PriceFrom $504	Free Cancellation	Rating 7.4 1,903 reviews	Search LATAM Airlines flights
American Airlines	PriceFrom $563	Free Cancellation	Rating 7.1 11,520 reviews	Search American Airlines flights
United Airlines	PriceFrom $574	Free Cancellation	Rating 7.4 9,499 reviews	Search United Airlines flights
Delta	PriceFrom $642	Free Cancellation	Rating 7.9 8,357 reviews	Search Delta flights

Viña del Mar

Valparaíso

Santa Cruz

Valle Nevado

San Fernando

Pichilemu

Zapallar

Why use momondo?

Why should I use momondo to find a flight deal from San Diego to Santiago?

It is quick and easy to find San Diego to Santiago flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Santiago that suits you.

Can I find flights from San Diego to Santiago with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for San Diego to Santiago flights to just show those with flexible booking policies.

How can momondo help me find flights from San Diego to Santiago?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from San Diego to Santiago.

I’m not ready to book a flight from San Diego to Santiago right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Santiago, momondo offers a useful price alert feature which will track prices for flights to Santiago from San Diego and alert you when they change.