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Cheap flights from San Diego to Santiago from $266

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from San Diego to Santiago departing on 10/6. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from San Diego to Santiago

Cheap round-trip flights

United Airlines Logo
10:20 am - 8:50 amSAN-SCL
17h 30m1 stop
United Airlines Logo
10:45 pm - 6:24 pmSCL-SAN
24h 39m1 stop
$514United Airlines
Find Deal
Thu, Nov 6 - Fri, Nov 14
United Airlines Logo
1:47 pm - 8:50 amSAN-SCL
14h 03m1 stop
United Airlines Logo
10:45 pm - 5:29 pmSCL-SAN
23h 44m2 stops
$518United Airlines
Find Deal
Mon, Nov 3 - Sat, Nov 15
Copa Airlines Logo
9:12 pm - 8:20 pmSAN-SCL
19h 08m1 stop
Copa Airlines Logo
5:12 am - 5:03 pmSCL-SAN
16h 51m1 stop
$526Copa Airlines
Find Deal
Mon, Oct 20 - Mon, Nov 3
Copa Airlines Logo
9:07 pm - 8:21 pmSAN-SCL
19h 14m1 stop
Copa Airlines Logo
3:23 am - 5:03 pmSCL-SAN
18h 40m1 stop
$532Copa Airlines
Find Deal
Fri, Oct 31 - Thu, Nov 6
American Airlines Logo
12:30 pm - 8:00 amSAN-SCL
15h 30m1 stop
American Airlines Logo
9:55 pm - 11:30 amSCL-SAN
17h 35m1 stop
$544American Airlines
Find Deal
Sun, Oct 12 - Sun, Oct 19
American Airlines Logo
7:15 am - 8:00 amSAN-SCL
20h 45m2 stops
American Airlines Logo
9:55 pm - 6:04 pmSCL-SAN
24h 09m2 stops
$548American Airlines
Find Deal
Tue, Oct 14 - Tue, Oct 21
Delta Logo
6:20 am - 6:00 amSAN-SCL
19h 40m2 stops
Delta Logo
10:10 pm - 4:08 pmSCL-SAN
21h 58m1 stop
$566Delta
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Thu, Oct 23 - Thu, Oct 30
Delta Logo
6:15 am - 6:50 amSAN-SCL
20h 35m2 stops
Delta Logo
8:50 am - 11:14 pmSCL-SAN
18h 24m2 stops
$568Delta
Find Deal
Tue, Oct 14 - Thu, Oct 23
LATAM Airlines Logo
6:15 am - 6:45 amSAN-SCL
20h 30m2 stops
LATAM Airlines Logo
4:35 am - 8:07 pmSCL-SAN
20h 32m2 stops
$575LATAM Airlines
Find Deal
Wed, Oct 22 - Sun, Nov 2
LATAM Airlines Logo
6:20 am - 6:50 amSAN-SCL
20h 30m2 stops
LATAM Airlines Logo
3:00 pm - 6:32 pmSCL-SAN
31h 32m2 stops
$579LATAM Airlines
Find Deal
Thu, Oct 23 - Thu, Oct 30

United Airlines flights from San Diego to Santiago

Our best United Airlines deals on San Diego to Santiago flight tickets
United Airlines
Nov 6
SAN8:00 amSan Diego
19h 50m
1 stop
SCL8:50 amSantiago Arturo Merino Benitez
Nov 11
SCL10:45 pmSantiago Arturo Merino Benitez
17h 16m
1 stop
SAN11:01 amSan Diego
$514
Find similar
United Airlines
Nov 3
SAN11:02 amSan Diego
16h 48m
2 stops
SCL8:50 amSantiago Arturo Merino Benitez
Nov 15
SCL10:45 pmSantiago Arturo Merino Benitez
21h 15m
2 stops
SAN3:00 pmSan Diego
$518
Find similar
United Airlines
Feb 28
SAN12:16 pmSan Diego
15h 34m
1 stop
SCL8:50 amSantiago Arturo Merino Benitez
Mar 7
SCL9:45 pmSantiago Arturo Merino Benitez
19h 42m
1 stop
SAN12:27 pmSan Diego
$804
Find similar

Copa Airlines flights from San Diego to Santiago

Our best Copa Airlines deals on San Diego to Santiago flight tickets
Copa Airlines
Oct 20
SAN9:12 pmSan Diego
19h 08m
1 stop
SCL8:20 pmSantiago Arturo Merino Benitez
Nov 3
SCL5:12 amSantiago Arturo Merino Benitez
16h 51m
1 stop
SAN5:03 pmSan Diego
$526
Find similar
Copa Airlines
Oct 31
SAN9:07 pmSan Diego
19h 14m
1 stop
SCL8:21 pmSantiago Arturo Merino Benitez
Nov 6
SCL3:23 amSantiago Arturo Merino Benitez
18h 40m
1 stop
SAN5:03 pmSan Diego
$532
Find similar
Copa Airlines
Oct 17
SAN9:12 pmSan Diego
19h 08m
1 stop
SCL8:20 pmSantiago Arturo Merino Benitez
Nov 3
SCL5:12 amSantiago Arturo Merino Benitez
16h 51m
1 stop
SAN5:03 pmSan Diego
$556
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from San Diego to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated September 17, 2025.
Use the filters below to find and compare flights from San Diego to Santiago that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

San DiegoSantiago

SAN - SCL

SANSCL

San Diego

Thu 11/6

10:20 am-8:50 am

1 stop17h 30m

Santiago Arturo Merino Benitez

Fri 11/14

10:45 pm-6:24 pm

1 stop24h 39m

$514

San DiegoSantiago

SAN - SCL

SANSCL

San Diego

Mon 11/3

1:47 pm-8:50 am

1 stop14h 03m

Santiago Arturo Merino Benitez

Sat 11/15

10:45 pm-5:29 pm

2 stops23h 44m

$518

San DiegoSantiago

SAN - SCL

SANSCL

San Diego

Mon 10/20

9:12 pm-8:20 pm

1 stop19h 08m

Santiago Arturo Merino Benitez

Mon 11/3

5:12 am-5:03 pm

1 stop16h 51m

$526

San DiegoSantiago

SAN - SCL

SANSCL

San Diego

Fri 10/31

9:07 pm-8:21 pm

1 stop19h 14m

Santiago Arturo Merino Benitez

Thu 11/6

3:23 am-5:03 pm

1 stop18h 40m

$532

San DiegoSantiago

SAN - SCL

SANSCL

San Diego

Sun 10/12

12:30 pm-8:00 am

1 stop15h 30m

Santiago Arturo Merino Benitez

Sun 10/19

9:55 pm-11:30 am

1 stop17h 35m

$544

San DiegoSantiago

SAN - SCL

SANSCL

San Diego

Tue 10/14

7:15 am-8:00 am

2 stops20h 45m

Santiago Arturo Merino Benitez

Tue 10/21

9:55 pm-6:04 pm

2 stops24h 09m

$548

San DiegoSantiago

SAN - SCL

SANSCL

San Diego

Thu 10/23

6:20 am-6:00 am

2 stops19h 40m

Santiago Arturo Merino Benitez

Thu 10/30

10:10 pm-4:08 pm

1 stop21h 58m

$566

San DiegoSantiago

SAN - SCL

SANSCL

San Diego

Tue 10/14

6:15 am-6:50 am

2 stops20h 35m

Santiago Arturo Merino Benitez

Thu 10/23

8:50 am-11:14 pm

2 stops18h 24m

$568

San DiegoSantiago

SAN - SCL

SANSCL

San Diego

Wed 10/22

6:15 am-6:45 am

2 stops20h 30m

Santiago Arturo Merino Benitez

Sun 11/2

4:35 am-8:07 pm

2 stops20h 32m

$575

San DiegoSantiago

SAN - SCL

SANSCL

San Diego

Thu 10/23

6:20 am-6:50 am

2 stops20h 30m

Santiago Arturo Merino Benitez

Thu 10/30

3:00 pm-6:32 pm

2 stops31h 32m

$579

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Santiago from

How to get the cheapest flight ticket from San Diego to Santiago

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Santiago?

In general, August is the cheapest month to fly from San Diego to Santiago. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $654. If you don’t want to visit Santiago in August, then you should wait until October to fly from San Diego, when ticket prices are also cheap, with an average price of $748.

What is the cheapest day to depart on your flight to Santiago?

The cheapest day to depart on your flight to Santiago is on a Sunday when prices can be found for as low as $1,003. This is often the case because there is less demand to fly during this day of the week. Be sure to avoid booking your departure on a Tuesday as prices are generally higher than usual. According to our data, the average ticket price to Santiago on Tuesday is $1,131.

What is the cheapest time of day to depart on your flight to Santiago?

At noon is the cheapest time of day to fly from San Diego to Santiago when you can find flight prices for as low as $882. Flying to Santiago at noon is an ideal time because this is during off-peak travel hours. In the afternoon is when there is more demand to fly to Santiago, so prices are often more expensive at around $1,072 per ticket.

How far in advance should I book a flight to Santiago?

You are more likely to see cheaper flights to Santiago from San Diego when booking weeks ahead of your departure date. In general, you can expect to find flights to Santiago for around $946 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Santiago from San Diego for as low as $453 on momondo.

How have San Diego to Santiago flight prices changed over time?

As of September 2025, prices for San Diego to Santiago flights are approximately 6% more expensive when compared to flights at the same time last year.

When to book flights from San Diego to Santiago

Are you open to changing your travel dates? Check out the ideal times to fly from San Diego to Santiago according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap San Diego to Santiago (SAN to SCL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from San Diego to Santiago

Direct flights

None
There are no direct flights from San Diego to Santiago. There are no popular flight routes from San Diego to Santiago.
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  • How far is San Diego to Santiago Arturo Merino Benitez by plane?

    There are 5476.6 mi between San Diego and Santiago Arturo Merino Benitez. In terms of flight time, this usually takes a little over 14h 03m.

  • When did momondo last update prices for flights from San Diego Airport to Santiago Arturo Merino Benitez Airport?

    Prices for flights from San Diego Airport to Santiago Arturo Merino Benitez Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from San Diego Airport to Santiago Arturo Merino Benitez Airport?

  • How old do you have to be to fly from San Diego Airport to Santiago Arturo Merino Benitez Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from San Diego Airport to Santiago Arturo Merino Benitez Airport.

  • What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?

    The required travel and health documents for your Santiago Arturo Merino Benitez Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Santiago Arturo Merino Benitez Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from San Diego to Santiago?

Best airlines flying from San Diego to Santiago

Compare and see reviews for airlines that fly from San Diego to Santiago with momondo
Airline
Rating
Free Cancellation
Price
Copa AirlinesPriceFrom $453Free CancellationRating
7.6
1,533 reviews
Search Copa Airlines flights
United AirlinesPriceFrom $542Free CancellationRating
7.4
8,926 reviews
Search United Airlines flights
LATAM AirlinesPriceFrom $556Free CancellationRating
7.5
1,849 reviews
Search LATAM Airlines flights
American AirlinesPriceFrom $599Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights
DeltaPriceFrom $792Free CancellationRating
7.9
7,961 reviews
Search Delta flights

Traveling to a place near Santiago?

Book flights to Santiago if you plan to visit one of these locations
Viña del Mar
Santa Cruz
Valparaíso
Valle Nevado
San Fernando
Pichilemu

Why use momondo?

Why should I use momondo to find a flight deal from San Diego to Santiago?

It is quick and easy to find San Diego to Santiago flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Santiago that suits you.

Can I find flights from San Diego to Santiago with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for San Diego to Santiago flights to just show those with flexible booking policies.

How can momondo help me find flights from San Diego to Santiago?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from San Diego to Santiago.

I’m not ready to book a flight from San Diego to Santiago right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Santiago, momondo offers a useful price alert feature which will track prices for flights to Santiago from San Diego and alert you when they change.

An easier way to manage your Santiago trip

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