Which airport is the most popular layover for flights between San Diego and Santiago?

Panama City (PTY) was the most common stop: 40% of momondo users choosing 1-stop flights on this route connected there.

Which layover airport has the shortest connection time from San Diego to Santiago?

Atlanta (ATL) has the shortest average layover time for this route: 1h 52m.

What is the cheapest airline that flies from San Diego to Santiago Arturo Merino Benitez?

LATAM Airlines and Air Canada are the most popular carriers operating from San Diego to Santiago Arturo Merino Benitez

What airlines fly to Santiago?

LATAM Airlines, American Airlines and Delta are the top three most popular airlines that fly to Santiago from San Diego according to our data. LATAM Airlines is the first choice among our users, with 39% of people opting to fly with this airline when traveling to Santiago. Keep in mind that there are 5 different airlines that fly to Santiago on a routine basis, so you have a few additional options to choose from.

Which layover airport has the shortest travel time from San Diego to Santiago?

Flights connecting via Atlanta (ATL) have the shortest average one-way travel time: 15h 05m.

Which layover airport offers the lowest fares from San Diego to Santiago?

Flights via Panama City (PTY) offer the lowest average round-trip price of $543.

When did momondo last update prices for flights from San Diego Airport to Santiago Arturo Merino Benitez Airport?

Prices for flights from San Diego Airport to Santiago Arturo Merino Benitez Airport are refreshed on a daily basis.

How many operators does momondo search for flights from San Diego Airport to Santiago Arturo Merino Benitez Airport?

There are 5 operators available for flights from San Diego Airport to Santiago Arturo Merino Benitez Airport as of February 2026.

How old do you have to be to fly from San Diego Airport to Santiago Arturo Merino Benitez Airport?

The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from San Diego Airport to Santiago Arturo Merino Benitez Airport.

What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?

The required travel and health documents for your Santiago Arturo Merino Benitez Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Santiago Arturo Merino Benitez Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

$293 Cheap Flights from San Diego to Santiago in 2026

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Find the cheapest flights from San Diego to Santiago

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9:18 pm - 7:23 pm

SAN

SCL

19h 05m

1 stop

4:17 am - 6:30 pm

SCL

SAN

17h 13m

1 stop

$600Copa Airlines

Wed, Apr 22 - Mon, Apr 27

12:50 pm - 7:15 am

SAN

SCL

15h 25m

1 stop

8:40 pm - 11:35 am

SCL

SAN

17h 55m

1 stop

$665LATAM Airlines

Thu, Jun 11 - Wed, Jul 8

10:40 pm - 1:35 pm

SAN

SCL

35h 55m

2 stops

4:10 am - 10:55 pm

SCL

SAN

21h 45m

2 stops

$695LATAM Airlines

Thu, Jun 11 - Wed, Jul 8

6:20 am - 5:35 am

SAN

SCL

19h 15m

2 stops

11:40 pm - 2:54 pm

SCL

SAN

19h 14m

1 stop

$733LATAM Airlines

Wed, Mar 11 - Wed, Mar 18

10:00 am - 5:35 am

SAN

SCL

16h 35m

1 stop

7:45 am - 10:55 pm

SCL

SAN

18h 10m

2 stops

$756LATAM Airlines

Thu, Jun 11 - Wed, Jul 8

10:30 pm - 7:40 am

SAN

SCL

29h 10m

1 stop

10:25 pm - 12:58 pm

SCL

SAN

18h 33m

1 stop

$769LATAM Airlines

Wed, Mar 11 - Wed, Mar 18

6:15 am - 7:40 am

SAN

SCL

21h 25m

1 stop

11:55 pm - 2:54 pm

SCL

SAN

18h 59m

1 stop

$778LATAM Airlines

Sun, Mar 8 - Sun, Mar 15

10:30 pm - 7:40 am

SAN

SCL

29h 10m

1 stop

10:25 pm - 11:09 pm

SCL

SAN

28h 44m

1 stop

$782LATAM Airlines

Fri, Mar 13 - Mon, Mar 23

12:50 pm - 7:15 am

SAN

SCL

15h 25m

1 stop

8:40 pm - 11:35 am

SCL

SAN

17h 55m

1 stop

$786LATAM Airlines

Thu, Jun 11 - Wed, Jul 8

8:00 am - 7:40 am

SAN

SCL

19h 40m

1 stop

5:15 am - 11:14 pm

SCL

SAN

21h 59m

2 stops

$795Delta

Wed, Mar 11 - Fri, Mar 20

Copa Airlines flights from San Diego to Santiago

Our best Copa Airlines deals on San Diego to Santiago flight tickets

Copa Airlines

Apr 22

SAN9:18 pmSan Diego

19h 05m

1 stop

SCL7:23 pmSantiago Arturo Merino Benitez

Apr 27

SCL4:17 amSantiago Arturo Merino Benitez

17h 13m

1 stop

SAN6:30 pmSan Diego

$600

Copa Airlines

Jun 3

SAN9:06 pmSan Diego

23h 20m

1 stop

SCL11:26 pmSantiago Arturo Merino Benitez

Jun 9

SCL12:38 amSantiago Arturo Merino Benitez

20h 52m

1 stop

SAN6:30 pmSan Diego

$927

American Airlines flights from San Diego to Santiago

Our best American Airlines deals on San Diego to Santiago flight tickets

American Airlines

Apr 14

SAN12:53 pmSan Diego

15h 12m

1 stop

SCL7:05 amSantiago Arturo Merino Benitez

Apr 17

SCL8:35 pmSantiago Arturo Merino Benitez

18h 18m

1 stop

SAN11:53 amSan Diego

$907

American Airlines

Mar 27

SAN9:53 amSan Diego

17h 07m

2 stops

SCL7:00 amSantiago Arturo Merino Benitez

Apr 3

SCL9:25 pmSantiago Arturo Merino Benitez

19h 21m

2 stops

SAN12:46 pmSan Diego

$946

American Airlines

Feb 19

SAN9:00 amSan Diego

19h 30m

2 stops

SCL9:30 amSantiago Arturo Merino Benitez

Mar 12

SCL9:20 pmSantiago Arturo Merino Benitez

18h 43m

2 stops

SAN12:03 pmSan Diego

$1,197

Fly from

Fly to

Route

Depart

Return

Price

San DiegoSantiago

SAN - SCL

SANSCL

San Diego

Wed 4/22

9:18 pm-7:23 pm

1 stop19h 05m

Santiago Arturo Merino Benitez

Mon 4/27

4:17 am-6:30 pm

1 stop17h 13m

$600

San DiegoSantiago

SAN - SCL

SANSCL

San Diego

Thu 6/11

12:50 pm-7:15 am

1 stop15h 25m

Santiago Arturo Merino Benitez

Wed 7/8

8:40 pm-11:35 am

1 stop17h 55m

$665

San DiegoSantiago

SAN - SCL

SANSCL

San Diego

Thu 6/11

10:40 pm-1:35 pm

2 stops35h 55m

Santiago Arturo Merino Benitez

Wed 7/8

4:10 am-10:55 pm

2 stops21h 45m

$695

San DiegoSantiago

SAN - SCL

SANSCL

San Diego

Wed 3/11

6:20 am-5:35 am

2 stops19h 15m

Santiago Arturo Merino Benitez

Wed 3/18

11:40 pm-2:54 pm

1 stop19h 14m

$733

San DiegoSantiago

SAN - SCL

SANSCL

San Diego

Thu 6/11

10:00 am-5:35 am

1 stop16h 35m

Santiago Arturo Merino Benitez

Wed 7/8

7:45 am-10:55 pm

2 stops18h 10m

$756

San DiegoSantiago

SAN - SCL

SANSCL

San Diego

Wed 3/11

10:30 pm-7:40 am

1 stop29h 10m

Santiago Arturo Merino Benitez

Wed 3/18

10:25 pm-12:58 pm

1 stop18h 33m

$769

San DiegoSantiago

SAN - SCL

SANSCL

San Diego

Sun 3/8

6:15 am-7:40 am

1 stop21h 25m

Santiago Arturo Merino Benitez

Sun 3/15

11:55 pm-2:54 pm

1 stop18h 59m

$778

San DiegoSantiago

SAN - SCL

SANSCL

San Diego

Fri 3/13

10:30 pm-7:40 am

1 stop29h 10m

Santiago Arturo Merino Benitez

Mon 3/23

10:25 pm-11:09 pm

1 stop28h 44m

$782

San DiegoSantiago

SAN - SCL

SANSCL

San Diego

Thu 6/11

12:50 pm-7:15 am

1 stop15h 25m

Santiago Arturo Merino Benitez

Wed 7/8

8:40 pm-11:35 am

1 stop17h 55m

$786

San DiegoSantiago

SAN - SCL

SANSCL

San Diego

Wed 3/11

8:00 am-7:40 am

1 stop19h 40m

Santiago Arturo Merino Benitez

Fri 3/20

5:15 am-11:14 pm

2 stops21h 59m

$795

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from San Diego to Santiago

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Layovers

What is the cheapest month to fly to Santiago?

In general, November is the cheapest month to fly from San Diego to Santiago. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $635. If you don’t want to visit Santiago in November, then you should wait until August to fly from San Diego, when ticket prices are also cheap, with an average price of $654.

How far in advance should I book a flight to Santiago?

You are more likely to see cheaper flights to Santiago from San Diego when booking weeks ahead of your departure date. In general, you can expect to find flights to Santiago for around $929 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Santiago from San Diego for as low as $453 on momondo.

How have San Diego to Santiago flight prices changed over time?

When to book flights from San Diego to Santiago

Are you open to changing your travel dates? Check out the ideal times to fly from San Diego to Santiago according to our flight data. Find out which month and days have the cheapest flights.

Estimated round-trip price

Cheap San Diego to Santiago (SAN to SCL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from San Diego to Santiago

Fastest flight time	14h 05m
Direct flights	None

The fastest flight from San Diego to Santiago takes 14h 05m

There are no direct flights from San Diego to Santiago. There are no popular flight routes from San Diego to Santiago.

Search flight deals

How far is San Diego to Santiago Arturo Merino Benitez by plane?
There are 5476.6 mi between San Diego and Santiago Arturo Merino Benitez. In terms of flight time, this usually takes a little over 14h 05m.
When did momondo last update prices for flights from San Diego Airport to Santiago Arturo Merino Benitez Airport?
Prices for flights from San Diego Airport to Santiago Arturo Merino Benitez Airport are refreshed on a daily basis.
How many operators does momondo search for flights from San Diego Airport to Santiago Arturo Merino Benitez Airport?
There are 5 operators available for flights from San Diego Airport to Santiago Arturo Merino Benitez Airport as of February 2026.
How old do you have to be to fly from San Diego Airport to Santiago Arturo Merino Benitez Airport?
The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from San Diego Airport to Santiago Arturo Merino Benitez Airport.
What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?
The required travel and health documents for your Santiago Arturo Merino Benitez Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Santiago Arturo Merino Benitez Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.
What is the most popular airline from San Diego to Santiago?
Based on momondo bookings for this flight route, the most popular airline on flight routes from San Diego to Santiago is LATAM Airlines (35% of total bookings). The next most popular airlines are American Airlines (26%), Delta (19%), and United Airlines (11%).

Best airlines flying from San Diego to Santiago

Compare and see reviews for airlines that fly from San Diego to Santiago with momondo

Airline	Rating	Free Cancellation	Price
Copa Airlines	PriceFrom $453	Free Cancellation	Rating 7.5 1,557 reviews	Search Copa Airlines flights
LATAM Airlines	PriceFrom $507	Free Cancellation	Rating 7.5 1,921 reviews	Search LATAM Airlines flights
American Airlines	PriceFrom $563	Free Cancellation	Rating 7.2 11,271 reviews	Search American Airlines flights
United Airlines	PriceFrom $574	Free Cancellation	Rating 7.4 9,279 reviews	Search United Airlines flights
Delta	PriceFrom $642	Free Cancellation	Rating 7.9 8,181 reviews	Search Delta flights

Viña del Mar

Valparaíso

Santa Cruz

Valle Nevado

San Fernando

Pichilemu

Zapallar

Why use momondo?

Why should I use momondo to find a flight deal from San Diego to Santiago?

It is quick and easy to find San Diego to Santiago flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Santiago that suits you.

Can I find flights from San Diego to Santiago with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for San Diego to Santiago flights to just show those with flexible booking policies.

How can momondo help me find flights from San Diego to Santiago?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from San Diego to Santiago.

I’m not ready to book a flight from San Diego to Santiago right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Santiago, momondo offers a useful price alert feature which will track prices for flights to Santiago from San Diego and alert you when they change.