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Cheap flights from San Diego to Panama from $225

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from San Diego to Panama departing on 3/30. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from San Diego to Panama

Cheap round-trip flights

Enter your travel dates to find the best prices.
Copa Airlines Logo
9:18 pm - 5:20 am
SAN
-
PTY
6h 02mnonstop
Copa Airlines Logo
1:15 pm - 6:14 pm
PTY
-
SAN
6h 59mnonstop
$510Copa Airlines
Mon, Mar 23 - Fri, Mar 27
Multiple Airlines Logo
9:59 pm - 1:55 am
SAN
-
PTY
25h 56m
2 stops
Multiple Airlines Logo
5:30 am - 9:29 pm
PTY
-
SAN
17h 59m
2 stops
$538Multiple Airlines
Thu, Apr 23 - Sun, May 3
Multiple Airlines Logo
10:02 pm - 1:55 am
SAN
-
PTY
25h 53m
2 stops
Multiple Airlines Logo
3:50 pm - 9:29 pm
PTY
-
SAN
31h 39m
2 stops
$555Multiple Airlines
Tue, Apr 21 - Sat, Apr 25
Multiple Airlines Logo
9:59 pm - 10:30 am
SAN
-
PTY
33h 31m
2 stops
Multiple Airlines Logo
7:50 pm - 8:29 pm
PTY
-
SAN
27h 39m
2 stops
$578Multiple Airlines
Mon, Jan 26 - Thu, Jan 29
Multiple Airlines Logo
10:02 pm - 1:55 am
SAN
-
PTY
25h 53m
2 stops
Multiple Airlines Logo
3:50 pm - 8:45 pm
PTY
-
SAN
30h 55m
2 stops
$583Multiple Airlines
Tue, Apr 7 - Tue, Apr 14
Copa Airlines Logo
8:18 pm - 5:20 am
SAN
-
PTY
6h 02mnonstop
Copa Airlines Logo
1:15 pm - 6:14 pm
PTY
-
SAN
6h 59mnonstop
$600Copa Airlines
Sun, Mar 1 - Sun, Mar 8
Copa Airlines Logo
8:18 pm - 5:20 am
SAN
-
PTY
6h 02mnonstop
Copa Airlines Logo
1:15 pm - 6:14 pm
PTY
-
SAN
6h 59mnonstop
$610Copa Airlines
Wed, Mar 4 - Wed, Mar 18
United Airlines Logo
6:15 am - 5:35 pm
SAN
-
DAV
33h 20m
2 stops
United Airlines Logo
10:05 am - 6:05 pm
DAV
-
SAN
34h 00m
2 stops
$1,040United Airlines
Fri, Apr 10 - Tue, Apr 14
United Airlines Logo
5:00 pm - 5:35 pm
SAN
-
DAV
22h 35m
2 stops
United Airlines Logo
10:05 am - 6:05 pm
DAV
-
SAN
34h 00m
2 stops
$1,060United Airlines
Fri, Apr 10 - Tue, Apr 14
United Airlines Logo
9:18 pm - 9:08 am
SAN
-
DAV
9h 50m
1 stop
United Airlines Logo
10:05 am - 8:12 pm
DAV
-
SAN
12h 07m
2 stops
$1,405United Airlines
Fri, Apr 10 - Tue, Apr 14

United Airlines flights from San Diego to Panama

Our best United Airlines deals on San Diego to Panama flight tickets
United Airlines
Apr 12
SAN6:15 amSan Diego
10h 22m
1 stop
PTY6:37 pmPanama City Tocumen Intl
Apr 23
PTY7:55 amPanama City Tocumen Intl
12h 10m
1 stop
SAN6:05 pmSan Diego
$625
United Airlines
Apr 12
SAN6:15 amSan Diego
10h 22m
1 stop
PTY6:37 pmPanama City Tocumen Intl
Apr 20
PTY7:55 amPanama City Tocumen Intl
14h 17m
2 stops
SAN8:12 pmSan Diego
$629
United Airlines
Mar 22
SAN8:00 amSan Diego
8h 38m
1 stop
PTY6:38 pmPanama City Tocumen Intl
Mar 31
PTY10:00 amPanama City Tocumen Intl
27h 04m
1 stop
SAN11:04 amSan Diego
$638

Copa Airlines flights from San Diego to Panama

Our best Copa Airlines deals on San Diego to Panama flight tickets
Copa Airlines
Mar 1
SAN8:18 pmSan Diego
6h 02m
PTY5:20 amPanama City Tocumen Intl
Mar 8
PTY1:15 pmPanama City Tocumen Intl
6h 59m
SAN6:14 pmSan Diego
$600
Copa Airlines
Mar 4
SAN8:18 pmSan Diego
6h 02m
PTY5:20 amPanama City Tocumen Intl
Mar 18
PTY1:15 pmPanama City Tocumen Intl
6h 59m
SAN6:14 pmSan Diego
$610
Copa Airlines
May 7
SAN5:00 pmSan Diego
19h 14m
1 stop
PTY2:14 pmPanama City Tocumen Intl
May 17
PTY10:00 amPanama City Tocumen Intl
9h 53m
1 stop
SAN5:53 pmSan Diego
$621

momondo Fare Finder

 
Customize your flight search to find flights from San Diego to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated January 13, 2026.
Use the filters below to find and compare flights from San Diego to Panama that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

Mon 3/23

9:18 pm-5:20 am

Nonstop6h 02m

Panama City Tocumen Intl

Fri 3/27

1:15 pm-6:14 pm

Nonstop6h 59m

$510

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

Thu 4/23

9:59 pm-1:55 am

2 stops25h 56m

Panama City Tocumen Intl

Sun 5/3

5:30 am-9:29 pm

2 stops17h 59m

$538

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

Tue 4/21

10:02 pm-1:55 am

2 stops25h 53m

Panama City Tocumen Intl

Sat 4/25

3:50 pm-9:29 pm

2 stops31h 39m

$555

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

Mon 1/26

9:59 pm-10:30 am

2 stops33h 31m

Panama City Tocumen Intl

Thu 1/29

7:50 pm-8:29 pm

2 stops27h 39m

$578

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

Tue 4/7

10:02 pm-1:55 am

2 stops25h 53m

Panama City Tocumen Intl

Tue 4/14

3:50 pm-8:45 pm

2 stops30h 55m

$583

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

Sun 3/1

8:18 pm-5:20 am

Nonstop6h 02m

Panama City Tocumen Intl

Sun 3/8

1:15 pm-6:14 pm

Nonstop6h 59m

$600

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

Wed 3/4

8:18 pm-5:20 am

Nonstop6h 02m

Panama City Tocumen Intl

Wed 3/18

1:15 pm-6:14 pm

Nonstop6h 59m

$610

San DiegoDavid

SAN - DAV

SANDAV

San Diego

Fri 4/10

6:15 am-5:35 pm

2 stops33h 20m

David Enrique Malek

Tue 4/14

10:05 am-6:05 pm

2 stops34h 00m

$1,040

San DiegoDavid

SAN - DAV

SANDAV

San Diego

Fri 4/10

5:00 pm-5:35 pm

2 stops22h 35m

David Enrique Malek

Tue 4/14

10:05 am-6:05 pm

2 stops34h 00m

$1,060

San DiegoDavid

SAN - DAV

SANDAV

San Diego

Fri 4/10

9:18 pm-9:08 am

1 stop9h 50m

David Enrique Malek

Tue 4/14

10:05 am-8:12 pm

2 stops12h 07m

$1,405

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Panama from

How to get the cheapest flight ticket from San Diego to Panama

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Panama?

The month of September is, on average, the cheapest month to fly to Panama from San Diego, with most prices found around $388. If you don’t want to visit Panama in September, then you should wait until August to fly from San Diego, when ticket prices are also cheap, with an average price of $439.

What is the cheapest day to depart on your flight to Panama?

According to our data, Thursday is the cheapest day to fly to Panama from San Diego. The lowest ticket price found for a Thursday departure recently was $230. Keep in mind that prices can always vary depending on your route and whether or not you are flying domestic or international. When flying out on a Saturday, the most expensive travel day of the week, you can expect to see flight prices from San Diego to Panama for around $1,200.

What is the cheapest San Diego to Panama flight route?

Fly from San Diego to Panama City Tocumen Intl for the best San Diego - Panama flight prices

How far in advance should I book a flight to Panama?

You are more likely to see cheaper flights to Panama from San Diego when booking weeks ahead of your departure date. In general, you can expect to find flights to Panama for around $544 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Panama from San Diego for as low as $364 on momondo.

What cabin class options are available on San Diego to Panama flights?

There are 3 cabin classes available to choose from on San Diego to Panama flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on San Diego to Panama flights?

You could potentially save up to 17% on your flight if you consider stops on a San Diego to Panama flight.

Cheap San Diego to Panama flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from San Diego to Panama

Best Price Found

$264

Fastest flight time

6h 02m

Direct flights

Mon, Tue, Thu and Sat

Airports in Panama

21 airports
The best one-way flight to Panama from San Diego in the past 72 hours is $264. The best round-trip flight deal from San Diego to Panama found on momondo in the last 72 hours is $417.
The fastest flight from San Diego to Panama takes 6h 02m
Direct flights go from San Diego to Panama on Monday, Tuesday, Thursday and Saturday. The only airline offering direct flights is Copa Airlines.
There are 21 airports in Panama. From San Diego there are direct flights to Panama City Tocumen Intl (PTY).
Search flight deals

  • When did momondo last update prices for flights from San Diego Airport to Panama?

    Prices for flights from San Diego Airport to Panama refresh daily.

  • How many operators does momondo search for flights from San Diego Airport to Panama?

  • How old do you have to be to fly from San Diego Airport to Panama?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from San Diego Airport to Panama.

  • What documentation or ID do you need to fly to Panama?

    The travel and health documents required for your trip to Panama can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Panama. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular plane model from San Diego to Panama?

Best airlines flying from San Diego to Panama

Compare and see reviews for airlines that fly from San Diego to Panama with momondo
Airline
Rating
Free Cancellation
Price
Copa AirlinesPriceFrom $334Free CancellationRating
7.6
1,559 reviews
Search Copa Airlines flights
United AirlinesPriceFrom $355Free CancellationRating
7.4
9,156 reviews
Search United Airlines flights
DeltaPriceFrom $355Free CancellationRating
7.9
8,040 reviews
Search Delta flights
American AirlinesPriceFrom $489Free CancellationRating
7.2
11,119 reviews
Search American Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from San Diego to Panama?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from San Diego to Panama. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from San Diego to Panama with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Panama from San Diego with this policy.

How can momondo help me find flights from San Diego to Panama?

Once all potential San Diego to Panama flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from San Diego to Panama right now. Can momondo alert me if prices change?

If you are not ready to book a flight from San Diego to Panama now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Panama and let you know when they change.

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