Cheap flights from San Diego to Panama from $257
This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from San Diego to Panama departing on 2/3. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Fly from
Fly to
Route
Depart
Return
San DiegoPanama City
SAN San Diego - PTY Panama City Tocumen Intl
SANPTY
San Diego
Tue 1/19
10:40 pm-1:26 pm
1 stop11h 46m
Panama City Tocumen Intl
Fri 1/22
2:26 pm-11:44 pm
1 stop12h 18m
San DiegoPanama City
SAN San Diego - PTY Panama City Tocumen Intl
SANPTY
San Diego
Wed 1/20
12:12 pm-3:55 pm
1 stop24h 43m
Panama City Tocumen Intl
Wed 1/27
2:26 pm-11:44 pm
1 stop12h 18m
San DiegoPanama City
SAN San Diego - PTY Panama City Tocumen Intl
SANPTY
San Diego
Mon 3/22
9:25 pm-2:30 pm
2 stops15h 05m
Panama City Tocumen Intl
Wed 3/31
3:31 pm-9:20 am
2 stops19h 49m
San DiegoPanama City
SAN San Diego - PTY Panama City Tocumen Intl
SANPTY
San Diego
Sun 11/22
10:30 pm-7:36 am
Nonstop6h 06m
Panama City Tocumen Intl
Fri 11/27
1:45 pm-5:15 pm
Nonstop6h 30m
San DiegoPanama City
SAN San Diego - PTY Panama City Tocumen Intl
SANPTY
San Diego
Wed 1/20
3:24 pm-3:55 pm
2 stops21h 31m
Panama City Tocumen Intl
Wed 1/27
2:26 pm-8:27 am
2 stops21h 01m
San DiegoPanama City
SAN San Diego - PTY Panama City Tocumen Intl
SANPTY
San Diego
Fri 11/6
10:30 pm-7:36 am
Nonstop6h 06m
Panama City Tocumen Intl
Sun 11/15
1:45 pm-5:15 pm
Nonstop6h 30m
San DiegoPanama City
SAN San Diego - PTY Panama City Tocumen Intl
SANPTY
San Diego
Wed 10/28
10:30 pm-6:43 am
Nonstop6h 13m
Panama City Tocumen Intl
Mon 11/2
1:45 pm-5:15 pm
Nonstop6h 30m
San DiegoPanama City
SAN San Diego - PTY Panama City Tocumen Intl
SANPTY
San Diego
Thu 10/29
12:38 pm-12:59 pm
1 stop22h 21m
Panama City Tocumen Intl
Wed 11/4
3:24 pm-12:44 pm
1 stop24h 20m
San DiegoPanama City
SAN San Diego - PTY Panama City Tocumen Intl
SANPTY
San Diego
Wed 11/4
8:05 am-7:38 pm
1 stop8h 33m
Panama City Tocumen Intl
Tue 11/10
8:55 am-3:54 pm
1 stop9h 59m
San DiegoPanama City
SAN San Diego - PTY Panama City Tocumen Intl
SANPTY
San Diego
Mon 11/16
8:05 am-7:38 pm
1 stop8h 33m
Panama City Tocumen Intl
Wed 11/18
8:55 am-3:54 pm
1 stop9h 59m
See travel insights to Panama from
How to get the cheapest flight ticket from San Diego to Panama
Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip
What is the cheapest month to fly to Panama?
The month of November is, on average, the cheapest month to fly to Panama from San Diego, with most prices found around $439. If you don’t want to visit Panama in November, then you should wait until February to fly from San Diego, when ticket prices are also cheap, with an average price of $494.
What is the cheapest day to depart on your flight to Panama?
According to our data, Tuesday is the cheapest day to fly to Panama from San Diego. The lowest ticket price found for a Tuesday departure recently was $544. Keep in mind that prices can always vary depending on your route and whether or not you are flying domestic or international. When flying out on a Saturday, the most expensive travel day of the week, you can expect to see flight prices from San Diego to Panama for around $1,005.
What is the cheapest San Diego to Panama flight route?
Fly from San Diego to Panama City Tocumen Intl for the best San Diego - Panama flight prices
How far in advance should I book a flight from San Diego to Panama?
You are more likely to see cheaper flights to Panama from San Diego when booking weeks ahead of your departure date. In general, you can expect to find flights to Panama for around $707 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Panama from San Diego for as low as $279 on momondo.
What cabin class options are available on San Diego to Panama flights?
There are 3 cabin classes available to choose from on San Diego to Panama flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.
Can stopping save me money on San Diego to Panama flights?
You could potentially save up to 68% on your flight if you consider stops on a San Diego to Panama flight.
What is the cheapest airline that flies from San Diego to Panama?
American Airlines and GOL are the most popular carriers operating from San Diego to Panama
What airlines fly to Panama?
Copa Airlines, United Airlines and American Airlines are the top three most popular airlines that fly to Panama from San Diego according to our data. Copa Airlines is the first choice among our users, with 71% of people opting to fly with this airline when traveling to Panama. Keep in mind that there are 3 different airlines that fly to Panama on a routine basis, so you have a few additional options to choose from.
How many flights depart from San Diego to Panama on average per day?
1 flights are operational daily from San Diego to Panama as of October 2026. The most popular departure time for this route is 10:00PM, with 100% of flights per day taking off in the evening.
How many flights depart from San Diego to Panama on average per week?
As of October 2026, 8 flights take off from San Diego and land in Panama each week. The most common flight departure day for this route is Mon, with 25% of weekly flights taking off on this day.
Cheap San Diego to Panama flight deals and tips
Find info about flight duration, direct flights, and airports for your flight from San Diego to Panama
Frequently asked questions about flying from San Diego to Panama
When did momondo last update prices for flights from San Diego Airport to Panama?
Prices for flights from San Diego Airport to Panama refresh daily.
How many operators does momondo search for flights from San Diego Airport to Panama?
As of October 2026, there are 3 operators available to choose from for flights from San Diego Airport to Panama.
How old do you have to be to fly from San Diego Airport to Panama?
Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from San Diego Airport to Panama.
What documentation or ID do you need to fly to Panama?
The travel and health documents required for your trip to Panama can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Panama. We always recommend checking with your airline or a trusted third party such as IATA to get advice.
What is the most popular plane model from San Diego to Panama?
Based on momondo bookings for this flight route, the most popular plane model on flight routes from San Diego to Panama is Boeing 737 MAX 9 (86.60% of total bookings). The next most popular plane models are Boeing 737 MAX 8 (3.09%), Boeing 737 (3.09%), and Boeing 737-900 (2.06%).
Best airlines flying from San Diego to Panama
Compare and see reviews for airlines that fly from San Diego to Panama with momondo
| Airline | Rating | Free Cancellation | Price | ||
|---|---|---|---|---|---|
| PriceFrom $279 | Free Cancellation | Rating 7.4 10,319 reviews | |||
| PriceFrom $309 | Free Cancellation | Rating 7.0 12,145 reviews | |||
| PriceFrom $365 | Free Cancellation | Rating 7.6 1,548 reviews |
Why use momondo?
Why should I use momondo to find a flight deal from San Diego to Panama?
momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from San Diego to Panama. Millions of users trust and use momondo every year so you are in good hands.
Can I find flights from San Diego to Panama with flexible booking policies on momondo?
Yes. momondo enables you to select and highlight flights to Panama from San Diego with this policy.
How can momondo help me find flights from San Diego to Panama?
Once all potential San Diego to Panama flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.
I’m not ready to book a flight from San Diego to Panama right now. Can momondo alert me if prices change?
If you are not ready to book a flight from San Diego to Panama now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Panama and let you know when they change.