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Cheap flights from San Diego to Panama from $252

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from San Diego to Panama departing on 6/9. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from San Diego to Panama

Cheap round-trip flights

Enter your travel dates to find the best prices.
Copa Airlines Logo
10:00 pm - 6:07 am
SAN
-
PTY
6h 07mnonstop
Copa Airlines Logo
1:39 pm - 6:30 pm
PTY
-
SAN
6h 51mnonstop
$570Copa Airlines
Fri, May 8 - Sun, May 17
American Airlines Logo
10:05 pm - 12:46 pm
SAN
-
PTY
12h 41m
1 stop
American Airlines Logo
1:49 pm - 10:28 pm
PTY
-
SAN
10h 39m
1 stop
$585American Airlines
Tue, May 5 - Tue, May 19
American Airlines Logo
2:04 pm - 12:46 pm
SAN
-
PTY
20h 42m
2 stops
American Airlines Logo
1:49 pm - 10:28 pm
PTY
-
SAN
10h 39m
1 stop
$589American Airlines
Thu, May 7 - Thu, May 14
American Airlines Logo
2:04 pm - 12:46 pm
SAN
-
PTY
20h 42m
2 stops
American Airlines Logo
1:49 pm - 10:09 am
PTY
-
SAN
22h 20m
2 stops
$594American Airlines
Fri, May 8 - Sun, May 17
American Airlines Logo
12:53 pm - 12:46 pm
SAN
-
PTY
21h 53m
1 stop
American Airlines Logo
1:49 pm - 10:28 pm
PTY
-
SAN
10h 39m
1 stop
$601American Airlines
Thu, May 7 - Thu, May 14
American Airlines Logo
4:32 pm - 12:46 pm
SAN
-
PTY
18h 14m
2 stops
American Airlines Logo
1:49 pm - 11:16 am
PTY
-
SAN
23h 27m
1 stop
$605American Airlines
Mon, May 4 - Mon, May 11
United Airlines Logo
6:15 am - 8:58 am
SAN
-
DAV
24h 43m
2 stops
United Airlines Logo
9:38 am - 8:04 pm
DAV
-
SAN
36h 26m
2 stops
$1,234United Airlines
Sat, May 2 - Wed, May 6
United Airlines Logo
6:15 am - 8:58 am
SAN
-
DAV
24h 43m
2 stops
United Airlines Logo
9:38 am - 9:25 pm
DAV
-
SAN
37h 47m
2 stops
$1,265United Airlines
Sat, May 2 - Wed, May 6
United Airlines Logo
6:15 am - 8:58 am
SAN
-
DAV
24h 43m
2 stops
United Airlines Logo
9:38 am - 6:30 pm
DAV
-
SAN
10h 52m
1 stop
$1,313United Airlines
Sat, May 2 - Wed, May 6
United Airlines Logo
6:05 pm - 8:58 am
SAN
-
DAV
12h 53m
2 stops
United Airlines Logo
9:38 am - 6:30 pm
DAV
-
SAN
10h 52m
1 stop
$1,370United Airlines
Sat, May 2 - Wed, May 6

Delta flights from San Diego to Panama

Our best Delta deals on San Diego to Panama flight tickets
Delta
May 15
SAN1:50 pmSan Diego
21h 00m
1 stop
PTY12:50 pmPanama City Tocumen Intl
May 22
PTY2:15 pmPanama City Tocumen Intl
11h 12m
1 stop
SAN11:27 pmSan Diego
$599
Delta
May 15
SAN1:50 pmSan Diego
21h 00m
1 stop
PTY12:50 pmPanama City Tocumen Intl
May 23
PTY2:15 pmPanama City Tocumen Intl
21h 24m
1 stop
SAN9:39 amSan Diego
$613
Delta
May 15
SAN1:50 pmSan Diego
21h 00m
1 stop
PTY12:50 pmPanama City Tocumen Intl
May 24
PTY2:15 pmPanama City Tocumen Intl
11h 12m
1 stop
SAN11:27 pmSan Diego
$649

American Airlines flights from San Diego to Panama

Our best American Airlines deals on San Diego to Panama flight tickets
American Airlines
May 5
SAN10:05 pmSan Diego
12h 41m
1 stop
PTY12:46 pmPanama City Tocumen Intl
May 19
PTY1:49 pmPanama City Tocumen Intl
10h 39m
1 stop
SAN10:28 pmSan Diego
$585
American Airlines
May 7
SAN2:04 pmSan Diego
20h 42m
2 stops
PTY12:46 pmPanama City Tocumen Intl
May 14
PTY1:49 pmPanama City Tocumen Intl
20h 49m
2 stops
SAN8:38 amSan Diego
$589
American Airlines
May 8
SAN2:04 pmSan Diego
20h 42m
2 stops
PTY12:46 pmPanama City Tocumen Intl
May 17
PTY1:49 pmPanama City Tocumen Intl
22h 20m
2 stops
SAN10:09 amSan Diego
$594

momondo Fare Finder

 
Customize your flight search to find flights from San Diego to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated April 11, 2026.
Use the filters below to find and compare flights from San Diego to Panama that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

Fri 5/8

10:00 pm-6:07 am

Nonstop6h 07m

Panama City Tocumen Intl

Sun 5/17

1:39 pm-6:30 pm

Nonstop6h 51m

$570

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

Tue 5/5

10:05 pm-12:46 pm

1 stop12h 41m

Panama City Tocumen Intl

Tue 5/19

1:49 pm-10:28 pm

1 stop10h 39m

$585

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

Thu 5/7

2:04 pm-12:46 pm

2 stops20h 42m

Panama City Tocumen Intl

Thu 5/14

1:49 pm-10:28 pm

1 stop10h 39m

$589

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

Fri 5/8

2:04 pm-12:46 pm

2 stops20h 42m

Panama City Tocumen Intl

Sun 5/17

1:49 pm-10:09 am

2 stops22h 20m

$594

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

Thu 5/7

12:53 pm-12:46 pm

1 stop21h 53m

Panama City Tocumen Intl

Thu 5/14

1:49 pm-10:28 pm

1 stop10h 39m

$601

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

Mon 5/4

4:32 pm-12:46 pm

2 stops18h 14m

Panama City Tocumen Intl

Mon 5/11

1:49 pm-11:16 am

1 stop23h 27m

$605

San DiegoDavid

SAN - DAV

SANDAV

San Diego

Sat 5/2

6:15 am-8:58 am

2 stops24h 43m

David Enrique Malek

Wed 5/6

9:38 am-8:04 pm

2 stops36h 26m

$1,234

San DiegoDavid

SAN - DAV

SANDAV

San Diego

Sat 5/2

6:15 am-8:58 am

2 stops24h 43m

David Enrique Malek

Wed 5/6

9:38 am-9:25 pm

2 stops37h 47m

$1,265

San DiegoDavid

SAN - DAV

SANDAV

San Diego

Sat 5/2

6:15 am-8:58 am

2 stops24h 43m

David Enrique Malek

Wed 5/6

9:38 am-6:30 pm

1 stop10h 52m

$1,313

San DiegoDavid

SAN - DAV

SANDAV

San Diego

Sat 5/2

6:05 pm-8:58 am

2 stops12h 53m

David Enrique Malek

Wed 5/6

9:38 am-6:30 pm

1 stop10h 52m

$1,370

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Panama from

How to get the cheapest flight ticket from San Diego to Panama

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Panama?

The month of September is, on average, the cheapest month to fly to Panama from San Diego, with most prices found around $388. If you don’t want to visit Panama in September, then you should wait until August to fly from San Diego, when ticket prices are also cheap, with an average price of $423.

What is the cheapest day to depart on your flight to Panama?

According to our data, Thursday is the cheapest day to fly to Panama from San Diego. The lowest ticket price found for a Thursday departure recently was $404. Keep in mind that prices can always vary depending on your route and whether or not you are flying domestic or international. When flying out on a Saturday, the most expensive travel day of the week, you can expect to see flight prices from San Diego to Panama for around $869.

What is the cheapest San Diego to Panama flight route?

Fly from San Diego to Panama City Tocumen Intl for the best San Diego - Panama flight prices

How far in advance should I book a flight to Panama?

You are more likely to see cheaper flights to Panama from San Diego when booking weeks ahead of your departure date. In general, you can expect to find flights to Panama for around $566 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Panama from San Diego for as low as $418 on momondo.

What cabin class options are available on San Diego to Panama flights?

There are 3 cabin classes available to choose from on San Diego to Panama flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on San Diego to Panama flights?

You could potentially save up to 39% on your flight if you consider stops on a San Diego to Panama flight.

Cheap San Diego to Panama flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from San Diego to Panama

Best Price Found

$230

Fastest flight time

6h 02m

Direct flights

Mon, Tue, Thu, Fri and Sat

Airports in Panama

21 airports
The best one-way flight to Panama from San Diego in the past 72 hours is $230. The best round-trip flight deal from San Diego to Panama found on momondo in the last 72 hours is $459.
The fastest flight from San Diego to Panama takes 6h 02m
Direct flights go from San Diego to Panama on Monday, Tuesday, Thursday, Friday and Saturday. There are no airlines offering direct flights.
There are 21 airports in Panama. From San Diego there are direct flights to Panama City Tocumen Intl (PTY).
Search flight deals

Frequently asked questions about flying from San Diego to Panama

  • When did momondo last update prices for flights from San Diego Airport to Panama?

    Prices for flights from San Diego Airport to Panama refresh daily.

  • How many operators does momondo search for flights from San Diego Airport to Panama?

  • How old do you have to be to fly from San Diego Airport to Panama?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from San Diego Airport to Panama.

  • What documentation or ID do you need to fly to Panama?

    The travel and health documents required for your trip to Panama can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Panama. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular plane model from San Diego to Panama?

Best airlines flying from San Diego to Panama

Compare and see reviews for airlines that fly from San Diego to Panama with momondo
Airline
Rating
Free Cancellation
Price
Copa AirlinesPriceFrom $235Free CancellationRating
7.5
1,574 reviews
Search Copa Airlines flights
United AirlinesPriceFrom $243Free CancellationRating
7.4
9,569 reviews
Search United Airlines flights
DeltaPriceFrom $285Free CancellationRating
7.9
8,405 reviews
Search Delta flights

Why use momondo?

Why should I use momondo to find a flight deal from San Diego to Panama?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from San Diego to Panama. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from San Diego to Panama with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Panama from San Diego with this policy.

How can momondo help me find flights from San Diego to Panama?

Once all potential San Diego to Panama flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from San Diego to Panama right now. Can momondo alert me if prices change?

If you are not ready to book a flight from San Diego to Panama now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Panama and let you know when they change.

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Find better results for your trip to Panama

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