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Cheap flights from San Diego to Panama from $228

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from San Diego to Panama departing on 6/5. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from San Diego to Panama

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
9:05 am - 1:55 am
SAN
-
PTY
14h 50m
2 stops
Multiple Airlines Logo
3:50 pm - 12:54 pm
PTY
-
SAN
23h 04m
2 stops
$545Multiple Airlines
fre., sep. 25 - fre., okt. 2
Multiple Airlines Logo
11:05 am - 10:30 am
SAN
-
PTY
21h 25m
2 stops
Multiple Airlines Logo
5:30 am - 2:38 pm
PTY
-
SAN
35h 08m
2 stops
$555Multiple Airlines
tor., maj 7 - tor., maj 14
Copa Airlines Logo
10:00 pm - 6:07 am
SAN
-
PTY
6h 07mnonstop
Copa Airlines Logo
1:39 pm - 6:30 pm
PTY
-
SAN
6h 51mnonstop
$570Copa Airlines
fre., maj 15 - man., maj 18
Multiple Airlines Logo
8:15 am - 1:55 am
SAN
-
PTY
15h 40m
2 stops
Multiple Airlines Logo
3:50 pm - 12:48 pm
PTY
-
SAN
22h 58m
2 stops
$572Multiple Airlines
man., maj 4 - tor., maj 7
Multiple Airlines Logo
10:04 am - 1:55 am
SAN
-
PTY
13h 51m
2 stops
Multiple Airlines Logo
5:30 am - 4:16 pm
PTY
-
SAN
12h 46m
2 stops
$579Multiple Airlines
lør., aug. 15 - lør., aug. 22
United Airlines Logo
6:15 am - 6:37 pm
SAN
-
PTY
10h 22m
1 stop
United Airlines Logo
10:00 am - 7:50 pm
PTY
-
SAN
11h 50m
1 stop
$585United Airlines
tor., maj 14 - tor., maj 21
Multiple Airlines Logo
11:05 am - 10:30 am
SAN
-
PTY
21h 25m
2 stops
Multiple Airlines Logo
3:50 pm - 2:38 pm
PTY
-
SAN
24h 48m
2 stops
$586Multiple Airlines
ons., maj 6 - ons., juni 3
American Airlines Logo
12:51 pm - 12:46 pm
SAN
-
PTY
21h 55m
2 stops
American Airlines Logo
1:49 pm - 8:38 am
PTY
-
SAN
20h 49m
2 stops
$589American Airlines
tir., maj 12 - tir., maj 19
United Airlines Logo
5:15 pm - 9:08 am
SAN
-
DAV
37h 53m
2 stops
United Airlines Logo
9:50 am - 9:25 pm
DAV
-
SAN
37h 35m
2 stops
$1,150United Airlines
man., aug. 10 - fre., aug. 14
Copa Airlines Logo
8:58 pm - 9:08 am
SAN
-
DAV
10h 10m
1 stop
Copa Airlines Logo
8:26 am - 8:01 pm
DAV
-
SAN
13h 35m
2 stops
$1,344Copa Airlines
søn., aug. 2 - lør., aug. 8

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Copa Airlines flights from San Diego to Panama

Our best Copa Airlines deals on San Diego to Panama flight tickets
Copa Airlines
May 15
SAN10:00 pmSan Diego
6h 07m
PTY6:07 amPanama City Tocumen Intl
May 18
PTY1:39 pmPanama City Tocumen Intl
6h 51m
SAN6:30 pmSan Diego
$570
Copa Airlines
May 6
SAN10:00 pmSan Diego
6h 07m
PTY6:07 amPanama City Tocumen Intl
May 10
PTY1:39 pmPanama City Tocumen Intl
6h 51m
SAN6:30 pmSan Diego
$620
Copa Airlines
Apr 29
SAN9:18 pmSan Diego
6h 02m
PTY5:20 amPanama City Tocumen Intl
May 6
PTY1:39 pmPanama City Tocumen Intl
6h 51m
SAN6:30 pmSan Diego
$670

American Airlines flights from San Diego to Panama

Our best American Airlines deals on San Diego to Panama flight tickets
American Airlines
May 12
SAN12:51 pmSan Diego
21h 55m
2 stops
PTY12:46 pmPanama City Tocumen Intl
May 19
PTY1:49 pmPanama City Tocumen Intl
20h 49m
2 stops
SAN8:38 amSan Diego
$589
American Airlines
May 15
SAN12:53 pmSan Diego
21h 53m
1 stop
PTY12:46 pmPanama City Tocumen Intl
May 18
PTY1:49 pmPanama City Tocumen Intl
23h 27m
1 stop
SAN11:16 amSan Diego
$601
American Airlines
May 11
SAN7:20 pmSan Diego
15h 26m
2 stops
PTY12:46 pmPanama City Tocumen Intl
May 18
PTY1:49 pmPanama City Tocumen Intl
23h 27m
1 stop
SAN11:16 amSan Diego
$605

momondo Fare Finder

 
Customize your flight search to find flights from San Diego to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated april 17, 2026.
Use the filters below to find and compare flights from San Diego to Panama that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

fre. 9/25

9:05 am-1:55 am

2 stops14h 50m

Panama City Tocumen Intl

fre. 10/2

3:50 pm-12:54 pm

2 stops23h 04m

$545

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

tor. 5/7

11:05 am-10:30 am

2 stops21h 25m

Panama City Tocumen Intl

tor. 5/14

5:30 am-2:38 pm

2 stops35h 08m

$555
Quickest round-trip

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

fre. 5/15

10:00 pm-6:07 am

Nonstop6h 07m

Panama City Tocumen Intl

man. 5/18

1:39 pm-6:30 pm

Nonstop6h 51m

$570

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

man. 5/4

8:15 am-1:55 am

2 stops15h 40m

Panama City Tocumen Intl

tor. 5/7

3:50 pm-12:48 pm

2 stops22h 58m

$572

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

lør. 8/15

10:04 am-1:55 am

2 stops13h 51m

Panama City Tocumen Intl

lør. 8/22

5:30 am-4:16 pm

2 stops12h 46m

$579

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

tor. 5/14

6:15 am-6:37 pm

1 stop10h 22m

Panama City Tocumen Intl

tor. 5/21

10:00 am-7:50 pm

1 stop11h 50m

$585

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

ons. 5/6

11:05 am-10:30 am

2 stops21h 25m

Panama City Tocumen Intl

ons. 6/3

3:50 pm-2:38 pm

2 stops24h 48m

$586

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

tir. 5/12

12:51 pm-12:46 pm

2 stops21h 55m

Panama City Tocumen Intl

tir. 5/19

1:49 pm-8:38 am

2 stops20h 49m

$589

San DiegoDavid

SAN - DAV

SANDAV

San Diego

man. 8/10

5:15 pm-9:08 am

2 stops37h 53m

David Enrique Malek

fre. 8/14

9:50 am-9:25 pm

2 stops37h 35m

$1,150

San DiegoDavid

SAN - DAV

SANDAV

San Diego

søn. 8/2

8:58 pm-9:08 am

1 stop10h 10m

David Enrique Malek

lør. 8/8

8:26 am-8:01 pm

2 stops13h 35m

$1,344

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Panama from

How to get the cheapest flight ticket from San Diego to Panama

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Panama?

The month of September is, on average, the cheapest month to fly to Panama from San Diego, with most prices found around $388. If you don’t want to visit Panama in September, then you should wait until August to fly from San Diego, when ticket prices are also cheap, with an average price of $423.

What is the cheapest day to depart on your flight to Panama?

According to our data, Thursday is the cheapest day to fly to Panama from San Diego. The lowest ticket price found for a Thursday departure recently was $404. Keep in mind that prices can always vary depending on your route and whether or not you are flying domestic or international. When flying out on a Saturday, the most expensive travel day of the week, you can expect to see flight prices from San Diego to Panama for around $869.

What is the cheapest San Diego to Panama flight route?

Fly from San Diego to Panama City Tocumen Intl for the best San Diego - Panama flight prices

How far in advance should I book a flight to Panama?

You are more likely to see cheaper flights to Panama from San Diego when booking weeks ahead of your departure date. In general, you can expect to find flights to Panama for around $568 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Panama from San Diego for as low as $418 on momondo.

What cabin class options are available on San Diego to Panama flights?

There are 3 cabin classes available to choose from on San Diego to Panama flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on San Diego to Panama flights?

You could potentially save up to 39% on your flight if you consider stops on a San Diego to Panama flight.

Cheap San Diego to Panama flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from San Diego to Panama

Best Price Found

$230

Fastest flight time

6h 02m

Direct flights

Mon, Tue, Thu, Fri and Sat

Airports in Panama

21 airports
The best one-way flight to Panama from San Diego in the past 72 hours is $230. The best round-trip flight deal from San Diego to Panama found on momondo in the last 72 hours is $458.
The fastest flight from San Diego to Panama takes 6h 02m
Direct flights go from San Diego to Panama on Monday, Tuesday, Thursday, Friday and Saturday. There are no airlines offering direct flights.
There are 21 airports in Panama. From San Diego there are direct flights to Panama City Tocumen Intl (PTY).
Search flight deals

Frequently asked questions about flying from San Diego to Panama

  • When did momondo last update prices for flights from San Diego Airport to Panama?

    Prices for flights from San Diego Airport to Panama refresh daily.

  • How many operators does momondo search for flights from San Diego Airport to Panama?

  • How old do you have to be to fly from San Diego Airport to Panama?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from San Diego Airport to Panama.

  • What documentation or ID do you need to fly to Panama?

    The travel and health documents required for your trip to Panama can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Panama. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular plane model from San Diego to Panama?

Best airlines flying from San Diego to Panama

Compare and see reviews for airlines that fly from San Diego to Panama with momondo
Airline
Rating
Free Cancellation
Price
Copa AirlinesPriceFrom $235Free CancellationRating
7.5
1,576 reviews
Search Copa Airlines flights
United AirlinesPriceFrom $243Free CancellationRating
7.4
9,604 reviews
Search United Airlines flights
DeltaPriceFrom $285Free CancellationRating
7.9
8,424 reviews
Search Delta flights

Why use momondo?

Why should I use momondo to find a flight deal from San Diego to Panama?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from San Diego to Panama. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from San Diego to Panama with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Panama from San Diego with this policy.

How can momondo help me find flights from San Diego to Panama?

Once all potential San Diego to Panama flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from San Diego to Panama right now. Can momondo alert me if prices change?

If you are not ready to book a flight from San Diego to Panama now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Panama and let you know when they change.

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søn. 5/17
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