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Cheap flights from San Diego to Panama from $182

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from San Diego to Panama departing on 4/15. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from San Diego to Panama

Cheap round-trip flights

Enter your travel dates to find the best prices.
Copa Airlines Logo
9:18 pm - 5:20 am
SAN
-
PTY
6h 02mnonstop
Copa Airlines Logo
1:15 pm - 6:14 pm
PTY
-
SAN
6h 59mnonstop
$510Copa Airlines
Mon, Mar 16 - Sun, Mar 22
United Airlines Logo
5:50 pm - 1:45 pm
SAN
-
PTY
17h 55m
1 stop
United Airlines Logo
7:55 am - 8:05 pm
PTY
-
SAN
14h 10m
1 stop
$525United Airlines
Mon, Mar 23 - Mon, Apr 6
United Airlines Logo
8:50 pm - 1:45 pm
SAN
-
PTY
14h 55m
2 stops
United Airlines Logo
3:30 pm - 9:54 am
PTY
-
SAN
20h 24m
2 stops
$529United Airlines
Sun, Mar 22 - Tue, Mar 31
United Airlines Logo
5:50 pm - 1:45 pm
SAN
-
PTY
17h 55m
1 stop
United Airlines Logo
3:30 pm - 11:04 am
PTY
-
SAN
21h 34m
1 stop
$536United Airlines
Sun, Mar 22 - Tue, Mar 31
Multiple Airlines Logo
9:59 pm - 1:55 am
SAN
-
PTY
25h 56m
2 stops
Multiple Airlines Logo
5:30 am - 9:29 pm
PTY
-
SAN
17h 59m
2 stops
$538Multiple Airlines
Thu, Apr 23 - Mon, Apr 27
American Airlines Logo
10:30 pm - 2:20 pm
SAN
-
PTY
13h 50m
1 stop
American Airlines Logo
3:10 pm - 12:10 pm
PTY
-
SAN
23h 00m
1 stop
$539American Airlines
Mon, Mar 16 - Mon, Mar 23
United Airlines Logo
5:50 pm - 6:38 pm
SAN
-
PTY
22h 48m
1 stop
United Airlines Logo
3:41 pm - 10:20 am
PTY
-
SAN
20h 39m
2 stops
$541United Airlines
Thu, Mar 19 - Sat, Mar 28
United Airlines Logo
11:03 am - 1:45 pm
SAN
-
PTY
24h 42m
2 stops
United Airlines Logo
3:41 pm - 10:22 am
PTY
-
SAN
20h 41m
2 stops
$544United Airlines
Mon, Mar 16 - Mon, Mar 23
United Airlines Logo
8:50 pm - 6:38 pm
SAN
-
PTY
19h 48m
2 stops
United Airlines Logo
3:30 pm - 8:05 pm
PTY
-
SAN
30h 35m
1 stop
$556United Airlines
Fri, Mar 27 - Sun, Apr 5
Copa Airlines Logo
9:18 pm - 9:04 am
SAN
-
DAV
9h 46m
1 stop
Copa Airlines Logo
9:48 am - 6:14 pm
DAV
-
SAN
10h 26m
1 stop
$610Copa Airlines
Wed, Mar 11 - Wed, Mar 18

United Airlines flights from San Diego to Panama

Our best United Airlines deals on San Diego to Panama flight tickets
United Airlines
Mar 23
SAN5:50 pmSan Diego
17h 55m
1 stop
PTY1:45 pmPanama City Tocumen Intl
Apr 6
PTY7:55 amPanama City Tocumen Intl
14h 10m
1 stop
SAN8:05 pmSan Diego
$525
United Airlines
Mar 22
SAN8:50 pmSan Diego
14h 55m
2 stops
PTY1:45 pmPanama City Tocumen Intl
Mar 31
PTY3:30 pmPanama City Tocumen Intl
20h 24m
2 stops
SAN9:54 amSan Diego
$529
United Airlines
Mar 22
SAN5:50 pmSan Diego
17h 55m
1 stop
PTY1:45 pmPanama City Tocumen Intl
Mar 31
PTY3:30 pmPanama City Tocumen Intl
21h 34m
1 stop
SAN11:04 amSan Diego
$536

American Airlines flights from San Diego to Panama

Our best American Airlines deals on San Diego to Panama flight tickets
American Airlines
Mar 16
SAN10:30 pmSan Diego
13h 50m
1 stop
PTY2:20 pmPanama City Tocumen Intl
Mar 23
PTY3:10 pmPanama City Tocumen Intl
23h 00m
1 stop
SAN12:10 pmSan Diego
$539
American Airlines
Feb 6
SAN10:25 pmSan Diego
12h 02m
1 stop
PTY1:27 pmPanama City Tocumen Intl
Feb 19
PTY2:40 pmPanama City Tocumen Intl
11h 00m
1 stop
SAN10:40 pmSan Diego
$750
American Airlines
Feb 9
SAN10:25 pmSan Diego
12h 02m
1 stop
PTY1:27 pmPanama City Tocumen Intl
Feb 15
PTY2:40 pmPanama City Tocumen Intl
20h 59m
2 stops
SAN8:39 amSan Diego
$769

momondo Fare Finder

 
Customize your flight search to find flights from San Diego to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated January 27, 2026.
Use the filters below to find and compare flights from San Diego to Panama that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

Mon 3/16

9:18 pm-5:20 am

Nonstop6h 02m

Panama City Tocumen Intl

Sun 3/22

1:15 pm-6:14 pm

Nonstop6h 59m

$510

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

Mon 3/23

5:50 pm-1:45 pm

1 stop17h 55m

Panama City Tocumen Intl

Mon 4/6

7:55 am-8:05 pm

1 stop14h 10m

$525

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

Sun 3/22

8:50 pm-1:45 pm

2 stops14h 55m

Panama City Tocumen Intl

Tue 3/31

3:30 pm-9:54 am

2 stops20h 24m

$529

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

Sun 3/22

5:50 pm-1:45 pm

1 stop17h 55m

Panama City Tocumen Intl

Tue 3/31

3:30 pm-11:04 am

1 stop21h 34m

$536

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

Thu 4/23

9:59 pm-1:55 am

2 stops25h 56m

Panama City Tocumen Intl

Mon 4/27

5:30 am-9:29 pm

2 stops17h 59m

$538

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

Mon 3/16

10:30 pm-2:20 pm

1 stop13h 50m

Panama City Tocumen Intl

Mon 3/23

3:10 pm-12:10 pm

1 stop23h 00m

$539

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

Thu 3/19

5:50 pm-6:38 pm

1 stop22h 48m

Panama City Tocumen Intl

Sat 3/28

3:41 pm-10:20 am

2 stops20h 39m

$541

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

Mon 3/16

11:03 am-1:45 pm

2 stops24h 42m

Panama City Tocumen Intl

Mon 3/23

3:41 pm-10:22 am

2 stops20h 41m

$544

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

Fri 3/27

8:50 pm-6:38 pm

2 stops19h 48m

Panama City Tocumen Intl

Sun 4/5

3:30 pm-8:05 pm

1 stop30h 35m

$556

San DiegoDavid

SAN - DAV

SANDAV

San Diego

Wed 3/11

9:18 pm-9:04 am

1 stop9h 46m

David Enrique Malek

Wed 3/18

9:48 am-6:14 pm

1 stop10h 26m

$610

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Panama from

How to get the cheapest flight ticket from San Diego to Panama

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Panama?

The month of September is, on average, the cheapest month to fly to Panama from San Diego, with most prices found around $388. If you don’t want to visit Panama in September, then you should wait until August to fly from San Diego, when ticket prices are also cheap, with an average price of $439.

What is the cheapest day to depart on your flight to Panama?

According to our data, Thursday is the cheapest day to fly to Panama from San Diego. The lowest ticket price found for a Thursday departure recently was $230. Keep in mind that prices can always vary depending on your route and whether or not you are flying domestic or international. When flying out on a Saturday, the most expensive travel day of the week, you can expect to see flight prices from San Diego to Panama for around $1,200.

What is the cheapest San Diego to Panama flight route?

Fly from San Diego to Panama City Tocumen Intl for the best San Diego - Panama flight prices

How far in advance should I book a flight to Panama?

You are more likely to see cheaper flights to Panama from San Diego when booking weeks ahead of your departure date. In general, you can expect to find flights to Panama for around $547 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Panama from San Diego for as low as $384 on momondo.

What cabin class options are available on San Diego to Panama flights?

There are 3 cabin classes available to choose from on San Diego to Panama flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on San Diego to Panama flights?

You could potentially save up to 9% on your flight if you consider stops on a San Diego to Panama flight.

Cheap San Diego to Panama flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from San Diego to Panama

Best Price Found

$293

Fastest flight time

6h 02m

Direct flights

Mon, Tue, Thu and Sat

Airports in Panama

21 airports
The best one-way flight to Panama from San Diego in the past 72 hours is $293. The best round-trip flight deal from San Diego to Panama found on momondo in the last 72 hours is $472.
The fastest flight from San Diego to Panama takes 6h 02m
Direct flights go from San Diego to Panama on Monday, Tuesday, Thursday and Saturday. There are no airlines offering direct flights.
There are 21 airports in Panama. From San Diego there are direct flights to Panama City Tocumen Intl (PTY).
Search flight deals

  • When did momondo last update prices for flights from San Diego Airport to Panama?

    Prices for flights from San Diego Airport to Panama refresh daily.

  • How many operators does momondo search for flights from San Diego Airport to Panama?

  • How old do you have to be to fly from San Diego Airport to Panama?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from San Diego Airport to Panama.

  • What documentation or ID do you need to fly to Panama?

    The travel and health documents required for your trip to Panama can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Panama. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular plane model from San Diego to Panama?

Best airlines flying from San Diego to Panama

Compare and see reviews for airlines that fly from San Diego to Panama with momondo
Airline
Rating
Free Cancellation
Price
Copa AirlinesPriceFrom $234Free CancellationRating
7.5
1,560 reviews
Search Copa Airlines flights
United AirlinesPriceFrom $279Free CancellationRating
7.4
9,206 reviews
Search United Airlines flights
DeltaPriceFrom $355Free CancellationRating
7.9
8,119 reviews
Search Delta flights
American AirlinesPriceFrom $489Free CancellationRating
7.2
11,198 reviews
Search American Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from San Diego to Panama?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from San Diego to Panama. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from San Diego to Panama with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Panama from San Diego with this policy.

How can momondo help me find flights from San Diego to Panama?

Once all potential San Diego to Panama flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from San Diego to Panama right now. Can momondo alert me if prices change?

If you are not ready to book a flight from San Diego to Panama now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Panama and let you know when they change.

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