Cheap flights from San Diego to Panama from $266

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from San Diego to Panama departing on 10/11. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from San Diego to Panama

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
6:48 pm - 10:30 am
SAN
-
PTY
13h 42m
2 stops
Multiple Airlines Logo
7:50 pm - 7:59 pm
PTY
-
SAN
26h 09m
2 stops
$618Multiple Airlines
Sun, Oct 25 - Sat, Oct 31
Multiple Airlines Logo
7:00 am - 1:55 am
SAN
-
PTY
16h 55m
2 stops
Multiple Airlines Logo
5:30 am - 6:29 pm
PTY
-
SAN
14h 59m
2 stops
$620Multiple Airlines
Fri, Oct 2 - Fri, Oct 16
Multiple Airlines Logo
9:01 am - 1:55 am
SAN
-
PTY
14h 54m
2 stops
Multiple Airlines Logo
5:30 am - 8:29 pm
PTY
-
SAN
16h 59m
2 stops
$638Multiple Airlines
Thu, May 28 - Mon, Jun 1
Multiple Airlines Logo
9:01 am - 10:30 am
SAN
-
PTY
23h 29m
2 stops
Multiple Airlines Logo
5:30 am - 6:27 pm
PTY
-
SAN
14h 57m
2 stops
$645Multiple Airlines
Wed, May 27 - Wed, Jun 3
Multiple Airlines Logo
7:43 am - 1:55 am
SAN
-
PTY
16h 12m
2 stops
Multiple Airlines Logo
5:30 am - 6:27 pm
PTY
-
SAN
14h 57m
2 stops
$655Multiple Airlines
Sat, May 23 - Fri, May 29
Copa Airlines Logo
9:03 pm - 5:20 am
SAN
-
PTY
6h 17mnonstop
Copa Airlines Logo
1:48 pm - 6:30 pm
PTY
-
SAN
6h 42mnonstop
$676Copa Airlines
Fri, Sep 25 - Fri, Oct 2
Delta Logo
10:53 am - 12:50 pm
SAN
-
PTY
23h 57m
1 stop
Delta Logo
2:15 pm - 12:38 pm
PTY
-
SAN
24h 23m
1 stop
$678Delta
Sun, May 17 - Sun, May 24
United Airlines Logo
6:50 pm - 6:37 pm
SAN
-
PTY
21h 47m
2 stops
United Airlines Logo
10:00 am - 5:46 pm
PTY
-
SAN
9h 46m
1 stop
$682United Airlines
Fri, Sep 25 - Fri, Oct 2
Copa Airlines Logo
9:03 pm - 5:20 am
SAN
-
PTY
6h 17mnonstop
Copa Airlines Logo
1:48 pm - 6:30 pm
PTY
-
SAN
6h 42mnonstop
$686Copa Airlines
Fri, Sep 25 - Fri, Oct 2
United Airlines Logo
8:00 am - 9:10 am
SAN
-
DAV
23h 10m
2 stops
United Airlines Logo
9:50 am - 10:58 am
DAV
-
SAN
27h 08m
2 stops
$1,135United Airlines
Tue, Oct 13 - Sat, Oct 17

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Copa Airlines flights from San Diego to Panama

Our best Copa Airlines deals on San Diego to Panama flight tickets
Copa Airlines
Sep 25
SAN9:03 pmSan Diego
6h 17m
PTY5:20 amPanama City Tocumen Intl
Oct 2
PTY1:48 pmPanama City Tocumen Intl
6h 42m
SAN6:30 pmSan Diego
$676
Copa Airlines
Sep 25
SAN9:03 pmSan Diego
6h 17m
PTY5:20 amPanama City Tocumen Intl
Oct 2
PTY1:48 pmPanama City Tocumen Intl
6h 42m
SAN6:30 pmSan Diego
$686
Copa Airlines
Jul 6
SAN10:00 pmSan Diego
6h 22m
PTY6:22 amPanama City Tocumen Intl
Jul 15
PTY2:01 pmPanama City Tocumen Intl
6h 29m
SAN6:30 pmSan Diego
$706

Delta flights from San Diego to Panama

Our best Delta deals on San Diego to Panama flight tickets
Delta
May 17
SAN10:53 amSan Diego
23h 57m
1 stop
PTY12:50 pmPanama City Tocumen Intl
May 24
PTY2:15 pmPanama City Tocumen Intl
24h 23m
1 stop
SAN12:38 pmSan Diego
$678
Delta
Jul 23
SAN9:30 pmSan Diego
13h 35m
1 stop
PTY1:05 pmPanama City Tocumen Intl
Aug 14
PTY2:20 pmPanama City Tocumen Intl
24h 13m
1 stop
SAN12:33 pmSan Diego
$707
Delta
May 14
SAN10:25 pmSan Diego
12h 25m
1 stop
PTY12:50 pmPanama City Tocumen Intl
May 25
PTY2:15 pmPanama City Tocumen Intl
11h 12m
1 stop
SAN11:27 pmSan Diego
$725

momondo Fare Finder

 
Customize your flight search to find flights from San Diego to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated May 6, 2026.
Use the filters below to find and compare flights from San Diego to Panama that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

Sun 10/25

6:48 pm-10:30 am

2 stops13h 42m

Panama City Tocumen Intl

Sat 10/31

7:50 pm-7:59 pm

2 stops26h 09m

$618

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

Fri 10/2

7:00 am-1:55 am

2 stops16h 55m

Panama City Tocumen Intl

Fri 10/16

5:30 am-6:29 pm

2 stops14h 59m

$620

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

Thu 5/28

9:01 am-1:55 am

2 stops14h 54m

Panama City Tocumen Intl

Mon 6/1

5:30 am-8:29 pm

2 stops16h 59m

$638

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

Wed 5/27

9:01 am-10:30 am

2 stops23h 29m

Panama City Tocumen Intl

Wed 6/3

5:30 am-6:27 pm

2 stops14h 57m

$645

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

Sat 5/23

7:43 am-1:55 am

2 stops16h 12m

Panama City Tocumen Intl

Fri 5/29

5:30 am-6:27 pm

2 stops14h 57m

$655
Quickest round-trip

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

Fri 9/25

9:03 pm-5:20 am

Nonstop6h 17m

Panama City Tocumen Intl

Fri 10/2

1:48 pm-6:30 pm

Nonstop6h 42m

$676

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

Sun 5/17

10:53 am-12:50 pm

1 stop23h 57m

Panama City Tocumen Intl

Sun 5/24

2:15 pm-12:38 pm

1 stop24h 23m

$678

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

Fri 9/25

6:50 pm-6:37 pm

2 stops21h 47m

Panama City Tocumen Intl

Fri 10/2

10:00 am-5:46 pm

1 stop9h 46m

$682

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

Fri 9/25

9:03 pm-5:20 am

Nonstop6h 17m

Panama City Tocumen Intl

Fri 10/2

1:48 pm-6:30 pm

Nonstop6h 42m

$686

San DiegoDavid

SAN - DAV

SANDAV

San Diego

Tue 10/13

8:00 am-9:10 am

2 stops23h 10m

David Enrique Malek

Sat 10/17

9:50 am-10:58 am

2 stops27h 08m

$1,135

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Panama from

How to get the cheapest flight ticket from San Diego to Panama

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Panama?

The month of September is, on average, the cheapest month to fly to Panama from San Diego, with most prices found around $145. If you don’t want to visit Panama in September, then you should wait until August to fly from San Diego, when ticket prices are also cheap, with an average price of $169.

What is the cheapest day to depart on your flight to Panama?

According to our data, Wednesday is the cheapest day to fly to Panama from San Diego. The lowest ticket price found for a Wednesday departure recently was $501. Keep in mind that prices can always vary depending on your route and whether or not you are flying domestic or international. When flying out on a Saturday, the most expensive travel day of the week, you can expect to see flight prices from San Diego to Panama for around $869.

What is the cheapest San Diego to Panama flight route?

Fly from San Diego to Panama City Tocumen Intl for the best San Diego - Panama flight prices

How far in advance should I book a flight from San Diego to Panama?

You are more likely to see cheaper flights to Panama from San Diego when booking weeks ahead of your departure date. In general, you can expect to find flights to Panama for around $582 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Panama from San Diego for as low as $418 on momondo.

Can stopping save me money on San Diego to Panama flights?

You could potentially save up to 39% on your flight if you consider stops on a San Diego to Panama flight.

Cheap San Diego to Panama flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from San Diego to Panama

Best Price Found

$246

Fastest flight time

6h 07m

Direct flights

Mon, Tue, Thu and Sat

Airports in Panama

21 airports
The best one-way flight to Panama from San Diego in the past 72 hours is $246. The best round-trip flight deal from San Diego to Panama found on momondo in the last 72 hours is $508.
The fastest flight from San Diego to Panama takes 6h 07m
Direct flights go from San Diego to Panama on Monday, Tuesday, Thursday and Saturday. There are no airlines offering direct flights.
There are 21 airports in Panama. From San Diego there are direct flights to Panama City Tocumen Intl (PTY).

Frequently asked questions about flying from San Diego to Panama

  • When did momondo last update prices for flights from San Diego Airport to Panama?

    Prices for flights from San Diego Airport to Panama refresh daily.

  • How many operators does momondo search for flights from San Diego Airport to Panama?

  • How old do you have to be to fly from San Diego Airport to Panama?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from San Diego Airport to Panama.

  • What documentation or ID do you need to fly to Panama?

    The travel and health documents required for your trip to Panama can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Panama. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular plane model from San Diego to Panama?

Best airlines flying from San Diego to Panama

Compare and see reviews for airlines that fly from San Diego to Panama with momondo
Airline
Rating
Free Cancellation
Price
United AirlinesPriceFrom $243Free CancellationRating
7.4
9,684 reviews
Search United Airlines flights
DeltaPriceFrom $285Free CancellationRating
7.9
8,459 reviews
Search Delta flights
Copa AirlinesPriceFrom $334Free CancellationRating
7.5
1,580 reviews
Search Copa Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from San Diego to Panama?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from San Diego to Panama. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from San Diego to Panama with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Panama from San Diego with this policy.

How can momondo help me find flights from San Diego to Panama?

Once all potential San Diego to Panama flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from San Diego to Panama right now. Can momondo alert me if prices change?

If you are not ready to book a flight from San Diego to Panama now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Panama and let you know when they change.

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Fri 6/5
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