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Cheap flights from San Diego to Panama from $270

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from San Diego to Panama departing on 8/12. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from San Diego to Panama

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
7:59 pm - 10:30 am
SAN
-
PTY
12h 31m
2 stops
Multiple Airlines Logo
5:30 am - 5:10 pm
PTY
-
SAN
13h 40m
2 stops
$548Multiple Airlines
Mon, Aug 24 - Fri, Aug 28
Multiple Airlines Logo
10:02 pm - 1:55 am
SAN
-
PTY
25h 53m
2 stops
Multiple Airlines Logo
5:30 am - 10:59 pm
PTY
-
SAN
19h 29m
2 stops
$602Multiple Airlines
Fri, Aug 14 - Sun, Aug 30
Multiple Airlines Logo
9:30 pm - 1:55 am
SAN
-
PTY
26h 25m
3 stops
Multiple Airlines Logo
3:50 pm - 4:11 pm
PTY
-
SAN
26h 21m
2 stops
$613Multiple Airlines
Mon, Aug 24 - Fri, Aug 28
Multiple Airlines Logo
10:48 am - 10:30 am
SAN
-
PTY
20h 42m
2 stops
Multiple Airlines Logo
3:50 pm - 9:37 am
PTY
-
SAN
20h 47m
2 stops
$618Multiple Airlines
Fri, Nov 6 - Sat, Nov 14
Delta Logo
10:40 pm - 12:56 pm
SAN
-
PTY
12h 16m
1 stop
Delta Logo
2:21 pm - 10:44 pm
PTY
-
SAN
10h 23m
1 stop
$621Delta
Thu, Sep 24 - Mon, Sep 28
Delta Logo
9:40 pm - 1:05 pm
SAN
-
PTY
13h 25m
1 stop
Delta Logo
2:20 pm - 11:00 pm
PTY
-
SAN
10h 40m
1 stop
$671Delta
Fri, Aug 14 - Sun, Aug 30
Copa Airlines Logo
9:07 pm - 7:17 pm
SAN
-
DAV
20h 10m
1 stop
Copa Airlines Logo
8:26 am - 6:30 pm
DAV
-
SAN
12h 04m
1 stop
$768Copa Airlines
Fri, Oct 9 - Mon, Oct 12
Copa Airlines Logo
5:00 pm - 7:17 pm
SAN
-
DAV
24h 17m
2 stops
Copa Airlines Logo
9:50 am - 6:30 pm
DAV
-
SAN
10h 40m
1 stop
$910Copa Airlines
Fri, Oct 9 - Mon, Oct 12
United Airlines Logo
8:00 am - 9:08 am
SAN
-
DAV
23h 08m
2 stops
United Airlines Logo
9:50 am - 5:46 pm
DAV
-
SAN
33h 56m
2 stops
$1,116United Airlines
Tue, Aug 25 - Fri, Aug 28
United Airlines Logo
8:00 am - 9:08 am
SAN
-
DAV
23h 08m
2 stops
United Airlines Logo
9:50 am - 9:25 pm
DAV
-
SAN
37h 35m
2 stops
$1,135United Airlines
Tue, Aug 25 - Fri, Aug 28

American Airlines flights from San Diego to Panama

Our best American Airlines deals on San Diego to Panama flight tickets
American Airlines
Sep 12
SAN11:00 pmSan Diego
13h 10m
1 stop
PTY2:10 pmPanama City Tocumen Intl
Sep 26
PTY3:40 pmPanama City Tocumen Intl
21h 16m
2 stops
SAN10:56 amSan Diego
$694
American Airlines
Sep 9
SAN7:55 pmSan Diego
16h 15m
2 stops
PTY2:10 pmPanama City Tocumen Intl
Sep 13
PTY3:40 pmPanama City Tocumen Intl
19h 26m
2 stops
SAN9:06 amSan Diego
$720
American Airlines
Aug 24
SAN10:45 pmSan Diego
11h 39m
1 stop
PTY12:24 pmPanama City Tocumen Intl
Aug 28
PTY1:24 pmPanama City Tocumen Intl
22h 55m
2 stops
SAN10:19 amSan Diego
$735

Copa Airlines flights from San Diego to Panama

Our best Copa Airlines deals on San Diego to Panama flight tickets
Copa Airlines
Aug 31
SAN8:58 pmSan Diego
6h 22m
PTY5:20 amPanama City Tocumen Intl
Sep 13
PTY1:55 pmPanama City Tocumen Intl
6h 35m
SAN6:30 pmSan Diego
$676
Copa Airlines
Aug 24
SAN8:58 pmSan Diego
6h 22m
PTY5:20 amPanama City Tocumen Intl
Aug 28
PTY2:01 pmPanama City Tocumen Intl
6h 29m
SAN6:30 pmSan Diego
$696
Copa Airlines
Jul 22
SAN10:00 pmSan Diego
6h 22m
PTY6:22 amPanama City Tocumen Intl
Jul 26
PTY2:01 pmPanama City Tocumen Intl
6h 29m
SAN6:30 pmSan Diego
$706

momondo Fare Finder

 
Customize your flight search to find flights from San Diego to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated May 23, 2026.
Use the filters below to find and compare flights from San Diego to Panama that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

Mon 8/24

7:59 pm-10:30 am

2 stops12h 31m

Panama City Tocumen Intl

Fri 8/28

5:30 am-5:10 pm

2 stops13h 40m

$548

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

Fri 8/14

10:02 pm-1:55 am

2 stops25h 53m

Panama City Tocumen Intl

Sun 8/30

5:30 am-10:59 pm

2 stops19h 29m

$602

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

Mon 8/24

9:30 pm-1:55 am

3 stops26h 25m

Panama City Tocumen Intl

Fri 8/28

3:50 pm-4:11 pm

2 stops26h 21m

$613

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

Fri 11/6

10:48 am-10:30 am

2 stops20h 42m

Panama City Tocumen Intl

Sat 11/14

3:50 pm-9:37 am

2 stops20h 47m

$618
Quickest round-trip

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

Thu 9/24

10:40 pm-12:56 pm

1 stop12h 16m

Panama City Tocumen Intl

Mon 9/28

2:21 pm-10:44 pm

1 stop10h 23m

$621

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

Fri 8/14

9:40 pm-1:05 pm

1 stop13h 25m

Panama City Tocumen Intl

Sun 8/30

2:20 pm-11:00 pm

1 stop10h 40m

$671

San DiegoDavid

SAN - DAV

SANDAV

San Diego

Fri 10/9

9:07 pm-7:17 pm

1 stop20h 10m

David Enrique Malek

Mon 10/12

8:26 am-6:30 pm

1 stop12h 04m

$768

San DiegoDavid

SAN - DAV

SANDAV

San Diego

Fri 10/9

5:00 pm-7:17 pm

2 stops24h 17m

David Enrique Malek

Mon 10/12

9:50 am-6:30 pm

1 stop10h 40m

$910

San DiegoDavid

SAN - DAV

SANDAV

San Diego

Tue 8/25

8:00 am-9:08 am

2 stops23h 08m

David Enrique Malek

Fri 8/28

9:50 am-5:46 pm

2 stops33h 56m

$1,116

San DiegoDavid

SAN - DAV

SANDAV

San Diego

Tue 8/25

8:00 am-9:08 am

2 stops23h 08m

David Enrique Malek

Fri 8/28

9:50 am-9:25 pm

2 stops37h 35m

$1,135

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Panama from

How to get the cheapest flight ticket from San Diego to Panama

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Panama?

The month of September is, on average, the cheapest month to fly to Panama from San Diego, with most prices found around $145. If you don’t want to visit Panama in September, then you should wait until June to fly from San Diego, when ticket prices are also cheap, with an average price of $169.

What is the cheapest day to depart on your flight to Panama?

According to our data, Wednesday is the cheapest day to fly to Panama from San Diego. The lowest ticket price found for a Wednesday departure recently was $505. Keep in mind that prices can always vary depending on your route and whether or not you are flying domestic or international. When flying out on a Saturday, the most expensive travel day of the week, you can expect to see flight prices from San Diego to Panama for around $1,200.

What is the cheapest San Diego to Panama flight route?

Fly from San Diego to Panama City Tocumen Intl for the best San Diego - Panama flight prices

How far in advance should I book a flight from San Diego to Panama?

You are more likely to see cheaper flights to Panama from San Diego when booking weeks ahead of your departure date. In general, you can expect to find flights to Panama for around $605 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Panama from San Diego for as low as $426 on momondo.

What cabin class options are available on San Diego to Panama flights?

There are 3 cabin classes available to choose from on San Diego to Panama flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on San Diego to Panama flights?

You could potentially save up to 39% on your flight if you consider stops on a San Diego to Panama flight.

Cheap San Diego to Panama flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from San Diego to Panama

Best Price Found

$246

Fastest flight time

6h 04m

Direct flights

Mon, Tue, Thu, Fri and Sat

Airports in Panama

21 airports
The best one-way flight to Panama from San Diego in the past 72 hours is $246. The best round-trip flight deal from San Diego to Panama found on momondo in the last 72 hours is $541.
The fastest flight from San Diego to Panama takes 6h 04m
Direct flights go from San Diego to Panama on Monday, Tuesday, Thursday, Friday and Saturday. There are no airlines offering direct flights.
There are 21 airports in Panama. From San Diego there are direct flights to Panama City Tocumen Intl (PTY).
Search flight deals

Frequently asked questions about flying from San Diego to Panama

  • When did momondo last update prices for flights from San Diego Airport to Panama?

    Prices for flights from San Diego Airport to Panama refresh daily.

  • How many operators does momondo search for flights from San Diego Airport to Panama?

  • How old do you have to be to fly from San Diego Airport to Panama?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from San Diego Airport to Panama.

  • What documentation or ID do you need to fly to Panama?

    The travel and health documents required for your trip to Panama can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Panama. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular plane model from San Diego to Panama?

Best airlines flying from San Diego to Panama

Compare and see reviews for airlines that fly from San Diego to Panama with momondo
Airline
Rating
Free Cancellation
Price
United AirlinesPriceFrom $243Free CancellationRating
7.4
9,752 reviews
Search United Airlines flights
Copa AirlinesPriceFrom $335Free CancellationRating
7.5
1,575 reviews
Search Copa Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from San Diego to Panama?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from San Diego to Panama. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from San Diego to Panama with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Panama from San Diego with this policy.

How can momondo help me find flights from San Diego to Panama?

Once all potential San Diego to Panama flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from San Diego to Panama right now. Can momondo alert me if prices change?

If you are not ready to book a flight from San Diego to Panama now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Panama and let you know when they change.

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