Cheap flights from San Diego to Panama from $236

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from San Diego to Panama departing on 4/23. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Copa Airlines Logo
10:00 pm - 6:07 am
SAN
-
PTY
6h 07mnonstop
Copa Airlines Logo
2:01 pm - 6:40 pm
PTY
-
SAN
6h 39mnonstop
$470Copa Airlines
Sun, May 31 - Fri, Jun 12
American Airlines Logo
10:05 pm - 12:46 pm
SAN
-
PTY
12h 41m
1 stop
American Airlines Logo
1:49 pm - 10:09 am
PTY
-
SAN
22h 20m
2 stops
$549American Airlines
Mon, May 4 - Mon, May 18
GOL Logo
2:04 pm - 12:46 pm
SAN
-
PTY
20h 42m
2 stops
GOL Logo
1:49 pm - 12:28 pm
PTY
-
SAN
24h 39m
2 stops
$551GOL
Wed, May 13 - Mon, May 18
Copa Airlines Logo
10:00 pm - 6:14 am
SAN
-
PTY
6h 14mnonstop
Copa Airlines Logo
2:01 pm - 6:40 pm
PTY
-
SAN
6h 39mnonstop
$553Copa Airlines
Sun, Jun 7 - Fri, Jun 19
American Airlines Logo
10:05 pm - 12:46 pm
SAN
-
PTY
12h 41m
1 stop
American Airlines Logo
1:49 pm - 11:16 am
PTY
-
SAN
23h 27m
1 stop
$558American Airlines
Mon, May 4 - Mon, May 18
American Airlines Logo
12:53 pm - 12:46 pm
SAN
-
PTY
21h 53m
1 stop
American Airlines Logo
1:14 pm - 11:51 am
PTY
-
SAN
24h 37m
2 stops
$561American Airlines
Tue, May 19 - Fri, May 22
American Airlines Logo
9:45 pm - 12:46 pm
SAN
-
PTY
13h 01m
2 stops
American Airlines Logo
1:49 pm - 11:16 am
PTY
-
SAN
23h 27m
1 stop
$563American Airlines
Mon, May 4 - Mon, May 18
GOL Logo
1:21 pm - 12:14 pm
SAN
-
PTY
20h 53m
2 stops
GOL Logo
1:14 pm - 9:04 am
PTY
-
SAN
21h 50m
2 stops
$591GOL
Thu, May 28 - Thu, Jun 11
United Airlines Logo
8:00 am - 9:10 am
SAN
-
DAV
23h 10m
2 stops
United Airlines Logo
9:50 am - 9:25 pm
DAV
-
SAN
37h 35m
2 stops
$1,076United Airlines
Fri, Sep 18 - Tue, Sep 22
United Airlines Logo
6:15 am - 8:58 am
SAN
-
DAV
24h 43m
2 stops
United Airlines Logo
9:38 am - 5:53 pm
DAV
-
SAN
34h 15m
2 stops
$1,109United Airlines
Sat, May 9 - Sat, May 16

United Airlines flights from San Diego to Panama

Our best United Airlines deals on San Diego to Panama flight tickets
United Airlines
Jul 6
SAN6:15 amSan Diego
10h 22m
1 stop
PTY6:37 pmPanama City Tocumen Intl
Jul 13
PTY10:00 amPanama City Tocumen Intl
9h 41m
1 stop
SAN5:41 pmSan Diego
$651
United Airlines
May 30
SAN6:27 pmSan Diego
19h 45m
2 stops
PTY4:12 pmPanama City Tocumen Intl
Jun 27
PTY3:30 pmPanama City Tocumen Intl
19h 32m
2 stops
SAN9:02 amSan Diego
$655
United Airlines
Jun 29
SAN6:15 amSan Diego
10h 22m
1 stop
PTY6:37 pmPanama City Tocumen Intl
Jul 5
PTY3:30 pmPanama City Tocumen Intl
21h 21m
1 stop
SAN10:51 amSan Diego
$664

Copa Airlines flights from San Diego to Panama

Our best Copa Airlines deals on San Diego to Panama flight tickets
Copa Airlines
May 31
SAN10:00 pmSan Diego
6h 07m
PTY6:07 amPanama City Tocumen Intl
Jun 12
PTY2:01 pmPanama City Tocumen Intl
6h 39m
SAN6:40 pmSan Diego
$470
Copa Airlines
Jun 7
SAN10:00 pmSan Diego
6h 14m
PTY6:14 amPanama City Tocumen Intl
Jun 19
PTY2:01 pmPanama City Tocumen Intl
6h 39m
SAN6:40 pmSan Diego
$553
Copa Airlines
Apr 29
SAN9:18 pmSan Diego
6h 02m
PTY5:20 amPanama City Tocumen Intl
May 6
PTY1:39 pmPanama City Tocumen Intl
6h 51m
SAN6:30 pmSan Diego
$590

momondo Fare Finder

 
Customize your flight search to find flights from San Diego to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated March 28, 2026.
Use the filters below to find and compare flights from San Diego to Panama that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

Sun 5/31

10:00 pm-6:07 am

Nonstop6h 07m

Panama City Tocumen Intl

Fri 6/12

2:01 pm-6:40 pm

Nonstop6h 39m

$470

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

Mon 5/4

10:05 pm-12:46 pm

1 stop12h 41m

Panama City Tocumen Intl

Mon 5/18

1:49 pm-10:09 am

2 stops22h 20m

$549

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

Wed 5/13

2:04 pm-12:46 pm

2 stops20h 42m

Panama City Tocumen Intl

Mon 5/18

1:49 pm-12:28 pm

2 stops24h 39m

$551

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

Sun 6/7

10:00 pm-6:14 am

Nonstop6h 14m

Panama City Tocumen Intl

Fri 6/19

2:01 pm-6:40 pm

Nonstop6h 39m

$553

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

Mon 5/4

10:05 pm-12:46 pm

1 stop12h 41m

Panama City Tocumen Intl

Mon 5/18

1:49 pm-11:16 am

1 stop23h 27m

$558

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

Tue 5/19

12:53 pm-12:46 pm

1 stop21h 53m

Panama City Tocumen Intl

Fri 5/22

1:14 pm-11:51 am

2 stops24h 37m

$561

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

Mon 5/4

9:45 pm-12:46 pm

2 stops13h 01m

Panama City Tocumen Intl

Mon 5/18

1:49 pm-11:16 am

1 stop23h 27m

$563

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

Thu 5/28

1:21 pm-12:14 pm

2 stops20h 53m

Panama City Tocumen Intl

Thu 6/11

1:14 pm-9:04 am

2 stops21h 50m

$591

San DiegoDavid

SAN - DAV

SANDAV

San Diego

Fri 9/18

8:00 am-9:10 am

2 stops23h 10m

David Enrique Malek

Tue 9/22

9:50 am-9:25 pm

2 stops37h 35m

$1,076

San DiegoDavid

SAN - DAV

SANDAV

San Diego

Sat 5/9

6:15 am-8:58 am

2 stops24h 43m

David Enrique Malek

Sat 5/16

9:38 am-5:53 pm

2 stops34h 15m

$1,109

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Panama from

How to get the cheapest flight ticket from San Diego to Panama

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Panama?

The month of September is, on average, the cheapest month to fly to Panama from San Diego, with most prices found around $388. If you don’t want to visit Panama in September, then you should wait until August to fly from San Diego, when ticket prices are also cheap, with an average price of $439.

What is the cheapest day to depart on your flight to Panama?

According to our data, Thursday is the cheapest day to fly to Panama from San Diego. The lowest ticket price found for a Thursday departure recently was $404. Keep in mind that prices can always vary depending on your route and whether or not you are flying domestic or international. When flying out on a Saturday, the most expensive travel day of the week, you can expect to see flight prices from San Diego to Panama for around $1,200.

What is the cheapest San Diego to Panama flight route?

Fly from San Diego to Panama City Tocumen Intl for the best San Diego - Panama flight prices

How far in advance should I book a flight to Panama?

You are more likely to see cheaper flights to Panama from San Diego when booking weeks ahead of your departure date. In general, you can expect to find flights to Panama for around $551 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Panama from San Diego for as low as $338 on momondo.

What cabin class options are available on San Diego to Panama flights?

There are 3 cabin classes available to choose from on San Diego to Panama flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on San Diego to Panama flights?

You could potentially save up to 34% on your flight if you consider stops on a San Diego to Panama flight.

Cheap San Diego to Panama flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from San Diego to Panama

Best Price Found

$205

Fastest flight time

6h 02m

Direct flights

Mon, Tue, Thu, Fri and Sat

Airports in Panama

21 airports
The best one-way flight to Panama from San Diego in the past 72 hours is $205. The best round-trip flight deal from San Diego to Panama found on momondo in the last 72 hours is $459.
The fastest flight from San Diego to Panama takes 6h 02m
Direct flights go from San Diego to Panama on Monday, Tuesday, Thursday, Friday and Saturday. There are no airlines offering direct flights.
There are 21 airports in Panama. From San Diego there are direct flights to Panama City Tocumen Intl (PTY).
  • When did momondo last update prices for flights from San Diego Airport to Panama?

    Prices for flights from San Diego Airport to Panama refresh daily.

  • How many operators does momondo search for flights from San Diego Airport to Panama?

  • How old do you have to be to fly from San Diego Airport to Panama?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from San Diego Airport to Panama.

  • What documentation or ID do you need to fly to Panama?

    The travel and health documents required for your trip to Panama can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Panama. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular plane model from San Diego to Panama?

Best airlines flying from San Diego to Panama

Compare and see reviews for airlines that fly from San Diego to Panama with momondo
Airline
Rating
Free Cancellation
Price
Copa AirlinesPriceFrom $234Free CancellationRating
7.5
1,579 reviews
Search Copa Airlines flights
United AirlinesPriceFrom $243Free CancellationRating
7.4
9,500 reviews
Search United Airlines flights
DeltaPriceFrom $285Free CancellationRating
7.9
8,357 reviews
Search Delta flights

Why use momondo?

Why should I use momondo to find a flight deal from San Diego to Panama?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from San Diego to Panama. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from San Diego to Panama with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Panama from San Diego with this policy.

How can momondo help me find flights from San Diego to Panama?

Once all potential San Diego to Panama flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from San Diego to Panama right now. Can momondo alert me if prices change?

If you are not ready to book a flight from San Diego to Panama now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Panama and let you know when they change.

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1 adult
Mon 4/27
Mon 5/4

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