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Cheap flights from San Diego to Panama from $165

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from San Diego to Panama departing on 10/15. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Cheap round-trip flights

Copa Airlines Logo
9:12 pm - 5:25 amSAN-PTY
6h 13mnonstop
Copa Airlines Logo
1:15 pm - 5:57 pmPTY-SAN
6h 42mnonstop
$389Copa Airlines
Find Deal
Wed, Oct 1 - Mon, Oct 6
United Airlines Logo
7:28 pm - 6:37 pmSAN-PTY
21h 09m2 stops
United Airlines Logo
3:35 pm - 12:15 amPTY-SAN
10h 40m1 stop
$393United Airlines
Find Deal
Wed, Oct 15 - Wed, Oct 22
Delta Logo
10:30 pm - 12:56 pmSAN-PTY
12h 26m1 stop
Delta Logo
2:21 pm - 9:48 amPTY-SAN
21h 27m1 stop
$395Delta
Find Deal
Sun, Oct 12 - Mon, Oct 20
United Airlines Logo
6:15 am - 8:10 pmSAN-PTY
11h 55m1 stop
United Airlines Logo
3:35 pm - 12:15 amPTY-SAN
10h 40m1 stop
$402United Airlines
Find Deal
Sun, Oct 12 - Sun, Oct 19
United Airlines Logo
8:00 am - 8:10 pmSAN-PTY
10h 10m1 stop
United Airlines Logo
3:35 pm - 7:56 amPTY-SAN
18h 21m1 stop
$403United Airlines
Find Deal
Wed, Oct 15 - Wed, Oct 22
United Airlines Logo
6:15 am - 6:37 pmSAN-PTY
10h 22m1 stop
United Airlines Logo
3:30 pm - 9:12 amPTY-SAN
19h 42m2 stops
$408United Airlines
Find Deal
Mon, Oct 13 - Mon, Oct 20
American Airlines Logo
10:45 pm - 2:31 pmSAN-PTY
13h 46m1 stop
American Airlines Logo
3:31 pm - 11:26 amPTY-SAN
21h 55m1 stop
$409American Airlines
Find Deal
Sun, Sep 28 - Sun, Oct 5
American Airlines Logo
10:45 pm - 2:31 pmSAN-PTY
13h 46m2 stops
American Airlines Logo
3:31 pm - 9:12 amPTY-SAN
19h 41m2 stops
$413American Airlines
Find Deal
Sun, Sep 28 - Sun, Oct 5
Copa Airlines Logo
9:12 pm - 5:25 amSAN-PTY
6h 13mnonstop
Copa Airlines Logo
1:15 pm - 5:57 pmPTY-SAN
6h 42mnonstop
$433Copa Airlines
Find Deal
Sun, Oct 12 - Sun, Oct 19
Delta Logo
6:20 am - 8:04 pmSAN-PTY
10h 44m1 stop
Delta Logo
3:27 pm - 11:11 pmPTY-SAN
10h 44m1 stop
$623Delta
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Sat, Jan 31 - Thu, Feb 12

Copa Airlines flights from San Diego to Panama

Our best Copa Airlines deals on San Diego to Panama flight tickets
Copa Airlines
Oct 1
SAN9:12 pmSan Diego
6h 13m
PTY5:25 amPanama City Tocumen Intl
Oct 6
PTY1:15 pmPanama City Tocumen Intl
6h 42m
SAN5:57 pmSan Diego
$389
Find similar
Copa Airlines
Oct 12
SAN9:12 pmSan Diego
6h 13m
PTY5:25 amPanama City Tocumen Intl
Oct 19
PTY1:15 pmPanama City Tocumen Intl
6h 42m
SAN5:57 pmSan Diego
$433
Find similar
Copa Airlines
Oct 8
SAN9:12 pmSan Diego
6h 13m
PTY5:25 amPanama City Tocumen Intl
Oct 12
PTY1:15 pmPanama City Tocumen Intl
6h 42m
SAN5:57 pmSan Diego
$441
Find similar

United Airlines flights from San Diego to Panama

Our best United Airlines deals on San Diego to Panama flight tickets
United Airlines
Oct 15
SAN7:28 pmSan Diego
21h 09m
2 stops
PTY6:37 pmPanama City Tocumen Intl
Oct 22
PTY3:35 pmPanama City Tocumen Intl
10h 40m
1 stop
SAN12:15 amSan Diego
$393
Find similar
United Airlines
Oct 12
SAN6:15 amSan Diego
11h 55m
1 stop
PTY8:10 pmPanama City Tocumen Intl
Oct 19
PTY3:35 pmPanama City Tocumen Intl
10h 40m
1 stop
SAN12:15 amSan Diego
$402
Find similar
United Airlines
Oct 15
SAN8:00 amSan Diego
10h 10m
1 stop
PTY8:10 pmPanama City Tocumen Intl
Oct 22
PTY3:35 pmPanama City Tocumen Intl
18h 21m
1 stop
SAN7:56 amSan Diego
$403
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from San Diego to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 31, 2025.
Use the filters below to find and compare flights from San Diego to Panama that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

Wed 10/1

9:12 pm-5:25 am

Nonstop6h 13m

Panama City Tocumen Intl

Mon 10/6

1:15 pm-5:57 pm

Nonstop6h 42m

$389

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

Wed 10/15

7:28 pm-6:37 pm

2 stops21h 09m

Panama City Tocumen Intl

Wed 10/22

3:35 pm-12:15 am

1 stop10h 40m

$393

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

Sun 10/12

10:30 pm-12:56 pm

1 stop12h 26m

Panama City Tocumen Intl

Mon 10/20

2:21 pm-9:48 am

1 stop21h 27m

$395

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

Sun 10/12

6:15 am-8:10 pm

1 stop11h 55m

Panama City Tocumen Intl

Sun 10/19

3:35 pm-12:15 am

1 stop10h 40m

$402

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

Wed 10/15

8:00 am-8:10 pm

1 stop10h 10m

Panama City Tocumen Intl

Wed 10/22

3:35 pm-7:56 am

1 stop18h 21m

$403

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

Mon 10/13

6:15 am-6:37 pm

1 stop10h 22m

Panama City Tocumen Intl

Mon 10/20

3:30 pm-9:12 am

2 stops19h 42m

$408

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

Sun 9/28

10:45 pm-2:31 pm

1 stop13h 46m

Panama City Tocumen Intl

Sun 10/5

3:31 pm-11:26 am

1 stop21h 55m

$409

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

Sun 9/28

10:45 pm-2:31 pm

2 stops13h 46m

Panama City Tocumen Intl

Sun 10/5

3:31 pm-9:12 am

2 stops19h 41m

$413

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

Sun 10/12

9:12 pm-5:25 am

Nonstop6h 13m

Panama City Tocumen Intl

Sun 10/19

1:15 pm-5:57 pm

Nonstop6h 42m

$433

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

Sat 1/31

6:20 am-8:04 pm

1 stop10h 44m

Panama City Tocumen Intl

Thu 2/12

3:27 pm-11:11 pm

1 stop10h 44m

$623

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Panama from

How to get the cheapest flight ticket from San Diego to Panama

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Panama?

The month of September is, on average, the cheapest month to fly to Panama from San Diego, with most prices found around $396. If you don’t want to visit Panama in September, then you should wait until August to fly from San Diego, when ticket prices are also cheap, with an average price of $439.

What is the cheapest day to depart on your flight to Panama?

According to our data, Wednesday is the cheapest day to fly to Panama from San Diego. The lowest ticket price found for a Wednesday departure recently was $472. Keep in mind that prices can always vary depending on your route and whether or not you are flying domestic or international. When flying out on a Tuesday, the most expensive travel day of the week, you can expect to see flight prices from San Diego to Panama for around $649.

What is the cheapest time of day to depart on your flight to Panama?

In the evening is the cheapest time of day to fly from San Diego to Panama when you can find flight prices for as low as $493. Flying to Panama in the evening is an ideal time because this is during off-peak travel hours. In the morning is when there is more demand to fly to Panama, so prices are often more expensive at around $687 per ticket.

What is the cheapest San Diego to Panama flight route?

Fly from San Diego to Panama City Tocumen Intl for the best San Diego - Panama flight prices

How far in advance should I book a flight to Panama?

You are more likely to see cheaper flights to Panama from San Diego when booking weeks ahead of your departure date. In general, you can expect to find flights to Panama for around $590 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Panama from San Diego for as low as $329 on momondo.

What cabin class options are available on San Diego to Panama flights?

There are 2 cabin classes available to choose from on San Diego to Panama flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on San Diego to Panama flights?

You could potentially save up to 12% on your flight if you consider stops on a San Diego to Panama flight.

Cheap San Diego to Panama flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from San Diego to Panama

Best Price Found

$186

Fastest flight time

6h 03m

Direct flights

Mon, Tue, Wed, Thu and Sat

Airports in Panama

1 airport
The best one-way flight to Panama from San Diego in the past 72 hours is $186. The best round-trip flight deal from San Diego to Panama found on momondo in the last 72 hours is $421.
The fastest flight from San Diego to Panama takes 6h 03m
Direct flights go from San Diego to Panama on Monday, Tuesday, Wednesday, Thursday and Saturday. There are no airlines offering direct flights.
There is 1 airport near Panama: Panama City Tocumen Intl (PTY)
Search flight deals

  • When did momondo last update prices for flights from San Diego Airport to Panama?

    Prices for flights from San Diego Airport to Panama refresh daily.

  • How many operators does momondo search for flights from San Diego Airport to Panama?

  • How old do you have to be to fly from San Diego Airport to Panama?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from San Diego Airport to Panama.

  • What documentation or ID do you need to fly to Panama?

    The travel and health documents required for your trip to Panama can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Panama. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular plane model from San Diego to Panama?

Best airlines flying from San Diego to Panama

Compare and see reviews for airlines that fly from San Diego to Panama with momondo
Airline
Rating
Free Cancellation
Price
Copa AirlinesPriceFrom $224Free CancellationRating
7.5
1,519 reviews
Search Copa Airlines flights
DeltaPriceFrom $355Free CancellationRating
7.9
7,976 reviews
Search Delta flights
United AirlinesPriceFrom $403Free CancellationRating
7.4
8,941 reviews
Search United Airlines flights
American AirlinesPriceFrom $586Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from San Diego to Panama?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from San Diego to Panama. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from San Diego to Panama with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Panama from San Diego with this policy.

How can momondo help me find flights from San Diego to Panama?

Once all potential San Diego to Panama flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from San Diego to Panama right now. Can momondo alert me if prices change?

If you are not ready to book a flight from San Diego to Panama now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Panama and let you know when they change.

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