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Cheap flights from San Diego to Panama from $330

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from San Diego to Panama departing on 7/23. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Find the cheapest flights from San Diego to Panama

Cheap round-trip flights

Enter your travel dates to find the best prices.
Copa Airlines Logo
10:00 pm - 6:17 am
SAN
-
PTY
6h 17mnonstop
Copa Airlines Logo
1:55 pm - 6:30 pm
PTY
-
SAN
6h 35mnonstop
$570Copa Airlines
Mon, Sep 14 - Sun, Sep 27
Delta Logo
10:25 pm - 12:58 pm
SAN
-
PTY
12h 33m
1 stop
Delta Logo
2:23 pm - 10:55 pm
PTY
-
SAN
10h 32m
1 stop
$585Delta
Mon, Sep 14 - Sun, Sep 27
United Airlines Logo
5:00 pm - 2:14 pm
SAN
-
PTY
19h 14m
2 stops
United Airlines Logo
3:30 pm - 11:35 am
PTY
-
SAN
22h 05m
2 stops
$589United Airlines
Mon, Sep 14 - Sun, Sep 27
United Airlines Logo
8:00 am - 6:37 pm
SAN
-
PTY
8h 37m
1 stop
United Airlines Logo
3:30 pm - 10:58 am
PTY
-
SAN
21h 28m
1 stop
$597United Airlines
Mon, Aug 31 - Sun, Sep 13
United Airlines Logo
12:01 pm - 2:14 pm
SAN
-
PTY
24h 13m
1 stop
United Airlines Logo
3:30 pm - 2:50 pm
PTY
-
SAN
25h 20m
2 stops
$602United Airlines
Mon, Aug 17 - Fri, Aug 21
United Airlines Logo
10:13 am - 6:37 pm
SAN
-
PTY
30h 24m
1 stop
United Airlines Logo
3:30 pm - 5:46 pm
PTY
-
SAN
28h 16m
1 stop
$609United Airlines
Fri, Sep 4 - Sat, Sep 12
Delta Logo
9:30 pm - 12:55 pm
SAN
-
PTY
13h 25m
1 stop
Delta Logo
2:20 pm - 11:00 pm
PTY
-
SAN
10h 40m
1 stop
$620Delta
Mon, Aug 17 - Fri, Aug 21
Copa Airlines Logo
8:00 am - 6:37 pm
SAN
-
PTY
8h 37m
1 stop
Copa Airlines Logo
10:00 am - 5:46 pm
PTY
-
SAN
9h 46m
1 stop
$634Copa Airlines
Fri, Sep 25 - Wed, Sep 30
Copa Airlines Logo
5:00 pm - 2:14 pm
SAN
-
PTY
19h 14m
2 stops
Copa Airlines Logo
10:00 am - 5:46 pm
PTY
-
SAN
9h 46m
1 stop
$638Copa Airlines
Fri, Sep 25 - Wed, Sep 30
Copa Airlines Logo
8:00 am - 6:37 pm
SAN
-
PTY
8h 37m
1 stop
Copa Airlines Logo
3:30 pm - 9:25 pm
PTY
-
SAN
31h 55m
1 stop
$646Copa Airlines
Tue, Aug 25 - Sun, Aug 30

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Delta flights from San Diego to Panama

Our best Delta deals on San Diego to Panama flight tickets
Delta
Sep 14
SAN10:25 pmSan Diego
12h 33m
1 stop
PTY12:58 pmPanama City Tocumen Intl
Sep 27
PTY2:23 pmPanama City Tocumen Intl
10h 32m
1 stop
SAN10:55 pmSan Diego
$585
Delta
Aug 17
SAN9:30 pmSan Diego
13h 25m
1 stop
PTY12:55 pmPanama City Tocumen Intl
Aug 21
PTY2:20 pmPanama City Tocumen Intl
10h 40m
1 stop
SAN11:00 pmSan Diego
$620
Delta
Oct 28
SAN9:40 pmSan Diego
13h 16m
1 stop
PTY12:56 pmPanama City Tocumen Intl
Nov 2
PTY3:21 pmPanama City Tocumen Intl
10h 42m
1 stop
SAN11:03 pmSan Diego
$711

United Airlines flights from San Diego to Panama

Our best United Airlines deals on San Diego to Panama flight tickets
United Airlines
Sep 14
SAN5:00 pmSan Diego
19h 14m
2 stops
PTY2:14 pmPanama City Tocumen Intl
Sep 27
PTY3:30 pmPanama City Tocumen Intl
22h 05m
2 stops
SAN11:35 amSan Diego
$589
United Airlines
Aug 31
SAN8:00 amSan Diego
8h 37m
1 stop
PTY6:37 pmPanama City Tocumen Intl
Sep 13
PTY3:30 pmPanama City Tocumen Intl
21h 28m
1 stop
SAN10:58 amSan Diego
$597
United Airlines
Aug 17
SAN12:01 pmSan Diego
24h 13m
1 stop
PTY2:14 pmPanama City Tocumen Intl
Aug 21
PTY3:30 pmPanama City Tocumen Intl
25h 20m
2 stops
SAN2:50 pmSan Diego
$602

momondo Fare Finder

 
Customize your flight search to find flights from San Diego to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated June 28, 2026.
Use the filters below to find and compare flights from San Diego to Panama that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

Mon 9/14

10:00 pm-6:17 am

Nonstop6h 17m

Panama City Tocumen Intl

Sun 9/27

1:55 pm-6:30 pm

Nonstop6h 35m

$570

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

Mon 9/14

10:25 pm-12:58 pm

1 stop12h 33m

Panama City Tocumen Intl

Sun 9/27

2:23 pm-10:55 pm

1 stop10h 32m

$585

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

Mon 9/14

5:00 pm-2:14 pm

2 stops19h 14m

Panama City Tocumen Intl

Sun 9/27

3:30 pm-11:35 am

2 stops22h 05m

$589

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

Mon 8/31

8:00 am-6:37 pm

1 stop8h 37m

Panama City Tocumen Intl

Sun 9/13

3:30 pm-10:58 am

1 stop21h 28m

$597

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

Mon 8/17

12:01 pm-2:14 pm

1 stop24h 13m

Panama City Tocumen Intl

Fri 8/21

3:30 pm-2:50 pm

2 stops25h 20m

$602

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

Fri 9/4

10:13 am-6:37 pm

1 stop30h 24m

Panama City Tocumen Intl

Sat 9/12

3:30 pm-5:46 pm

1 stop28h 16m

$609

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

Mon 8/17

9:30 pm-12:55 pm

1 stop13h 25m

Panama City Tocumen Intl

Fri 8/21

2:20 pm-11:00 pm

1 stop10h 40m

$620

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

Fri 9/25

8:00 am-6:37 pm

1 stop8h 37m

Panama City Tocumen Intl

Wed 9/30

10:00 am-5:46 pm

1 stop9h 46m

$634

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

Fri 9/25

5:00 pm-2:14 pm

2 stops19h 14m

Panama City Tocumen Intl

Wed 9/30

10:00 am-5:46 pm

1 stop9h 46m

$638

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

Tue 8/25

8:00 am-6:37 pm

1 stop8h 37m

Panama City Tocumen Intl

Sun 8/30

3:30 pm-9:25 pm

1 stop31h 55m

$646

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Panama from

How to get the cheapest flight ticket from San Diego to Panama

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Panama?

The month of September is, on average, the cheapest month to fly to Panama from San Diego, with most prices found around $169. If you don’t want to visit Panama in September, then you should wait until December to fly from San Diego, when ticket prices are also cheap, with an average price of $179.

What is the cheapest day to depart on your flight to Panama?

According to our data, Tuesday is the cheapest day to fly to Panama from San Diego. The lowest ticket price found for a Tuesday departure recently was $513. Keep in mind that prices can always vary depending on your route and whether or not you are flying domestic or international. When flying out on a Saturday, the most expensive travel day of the week, you can expect to see flight prices from San Diego to Panama for around $1,200.

What is the cheapest San Diego to Panama flight route?

Fly from San Diego to Panama City Tocumen Intl for the best San Diego - Panama flight prices

How far in advance should I book a flight from San Diego to Panama?

You are more likely to see cheaper flights to Panama from San Diego when booking weeks ahead of your departure date. In general, you can expect to find flights to Panama for around $645 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Panama from San Diego for as low as $446 on momondo.

What cabin class options are available on San Diego to Panama flights?

There are 3 cabin classes available to choose from on San Diego to Panama flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on San Diego to Panama flights?

You could potentially save up to 39% on your flight if you consider stops on a San Diego to Panama flight.

Cheap San Diego to Panama flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from San Diego to Panama

Best Price Found

$295

Fastest flight time

6h 06m

Direct flights

Mon, Tue, Thu, Fri and Sat

Airports in Panama

21 airports
The best one-way flight to Panama from San Diego in the past 72 hours is $295. The best round-trip flight deal from San Diego to Panama found on momondo in the last 72 hours is $450.
The fastest flight from San Diego to Panama takes 6h 06m
Direct flights go from San Diego to Panama on Monday, Tuesday, Thursday, Friday and Saturday. There are no airlines offering direct flights.
There are 21 airports in Panama. From San Diego there are direct flights to Panama City Tocumen Intl (PTY).
Search flight deals

Frequently asked questions about flying from San Diego to Panama

  • When did momondo last update prices for flights from San Diego Airport to Panama?

    Prices for flights from San Diego Airport to Panama refresh daily.

  • How many operators does momondo search for flights from San Diego Airport to Panama?

  • How old do you have to be to fly from San Diego Airport to Panama?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from San Diego Airport to Panama.

  • What documentation or ID do you need to fly to Panama?

    The travel and health documents required for your trip to Panama can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Panama. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular plane model from San Diego to Panama?

Best airlines flying from San Diego to Panama

Compare and see reviews for airlines that fly from San Diego to Panama with momondo
Airline
Rating
Free Cancellation
Price
United AirlinesPriceFrom $279Free CancellationRating
7.4
9,894 reviews
Search United Airlines flights
Copa AirlinesPriceFrom $367Free CancellationRating
7.6
1,566 reviews
Search Copa Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from San Diego to Panama?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from San Diego to Panama. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from San Diego to Panama with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Panama from San Diego with this policy.

How can momondo help me find flights from San Diego to Panama?

Once all potential San Diego to Panama flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from San Diego to Panama right now. Can momondo alert me if prices change?

If you are not ready to book a flight from San Diego to Panama now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Panama and let you know when they change.

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Find better results for your trip to Panama

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