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Cheap flights from San Diego to Panama from $175

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from San Diego to Panama departing on 1/16. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Cheap round-trip flights

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Copa Airlines Logo
8:16 pm - 5:20 amSAN-PTY
6h 04mnonstop
Copa Airlines Logo
1:45 pm - 5:41 pmPTY-SAN
6h 56mnonstop
$409Copa Airlines
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Wed, Jan 21 - Mon, Jan 26
United Airlines Logo
5:23 pm - 2:45 pmSAN-PTY
18h 22m1 stop
United Airlines Logo
8:55 am - 6:21 pmPTY-SAN
12h 26m1 stop
$424United Airlines
Find Deal
Fri, Dec 12 - Mon, Dec 15
United Airlines Logo
7:00 pm - 5:07 pmSAN-PTY
19h 07m2 stops
United Airlines Logo
11:35 am - 10:30 pmPTY-SAN
13h 55m2 stops
$428United Airlines
Find Deal
Fri, Dec 12 - Mon, Dec 15
United Airlines Logo
8:00 am - 7:38 pmSAN-PTY
8h 38m1 stop
United Airlines Logo
4:41 pm - 11:05 amPTY-SAN
21h 24m1 stop
$433United Airlines
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Wed, Jan 7 - Wed, Jan 21
Copa Airlines Logo
8:16 pm - 5:20 amSAN-PTY
6h 04mnonstop
Copa Airlines Logo
1:15 pm - 5:13 pmPTY-SAN
6h 58mnonstop
$434Copa Airlines
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Sun, Jan 11 - Sun, Feb 8
United Airlines Logo
5:23 pm - 2:45 pmSAN-PTY
18h 22m1 stop
United Airlines Logo
11:35 am - 7:56 pmPTY-SAN
11h 21m1 stop
$449United Airlines
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Fri, Dec 5 - Mon, Dec 15
United Airlines Logo
8:37 pm - 2:45 pmSAN-PTY
15h 08m2 stops
United Airlines Logo
4:41 pm - 10:27 amPTY-SAN
20h 46m2 stops
$450United Airlines
Find Deal
Wed, Jan 7 - Thu, Jan 15
United Airlines Logo
5:10 pm - 2:45 pmSAN-PTY
18h 35m1 stop
United Airlines Logo
8:55 am - 11:40 pmPTY-SAN
17h 45m2 stops
$453United Airlines
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Mon, Dec 29 - Mon, Feb 23
Copa Airlines Logo
8:12 pm - 5:20 amSAN-PTY
6h 08mnonstop
Copa Airlines Logo
1:45 pm - 5:37 pmPTY-SAN
6h 52mnonstop
$459Copa Airlines
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Sun, Dec 7 - Tue, Dec 16
United Airlines Logo
1:51 pm - 2:45 pmSAN-PTY
21h 54m1 stop
United Airlines Logo
4:41 pm - 10:27 amPTY-SAN
20h 46m2 stops
$460United Airlines
Find Deal
Thu, Jan 8 - Thu, Jan 15

United Airlines flights from San Diego to Panama

Our best United Airlines deals on San Diego to Panama flight tickets
United Airlines
Dec 12
SAN5:23 pmSan Diego
18h 22m
1 stop
PTY2:45 pmPanama City Tocumen Intl
Dec 15
PTY8:55 amPanama City Tocumen Intl
12h 26m
1 stop
SAN6:21 pmSan Diego
$424
Find similar
United Airlines
Dec 12
SAN7:00 pmSan Diego
19h 07m
2 stops
PTY5:07 pmPanama City Tocumen Intl
Dec 15
PTY11:35 amPanama City Tocumen Intl
13h 55m
2 stops
SAN10:30 pmSan Diego
$428
Find similar
United Airlines
Jan 7
SAN8:00 amSan Diego
8h 38m
1 stop
PTY7:38 pmPanama City Tocumen Intl
Jan 21
PTY4:41 pmPanama City Tocumen Intl
26h 55m
1 stop
SAN4:36 pmSan Diego
$433
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American Airlines flights from San Diego to Panama

Our best American Airlines deals on San Diego to Panama flight tickets
American Airlines
Dec 7
SAN10:35 pmSan Diego
12h 12m
1 stop
PTY1:47 pmPanama City Tocumen Intl
Dec 16
PTY2:50 pmPanama City Tocumen Intl
11h 10m
1 stop
SAN11:00 pmSan Diego
$424
Find similar
American Airlines
Jan 25
SAN10:25 pmSan Diego
12h 02m
1 stop
PTY1:27 pmPanama City Tocumen Intl
Feb 1
PTY4:50 pmPanama City Tocumen Intl
22h 37m
1 stop
SAN12:27 pmSan Diego
$510
Find similar
American Airlines
Jan 29
SAN10:25 pmSan Diego
14h 13m
1 stop
PTY3:38 pmPanama City Tocumen Intl
Feb 4
PTY2:27 pmPanama City Tocumen Intl
11h 42m
1 stop
SAN11:09 pmSan Diego
$515
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momondo Fare Finder

 
Customize your flight search to find flights from San Diego to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated November 25, 2025.
Use the filters below to find and compare flights from San Diego to Panama that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

Wed 1/21

8:16 pm-5:20 am

Nonstop6h 04m

Panama City Tocumen Intl

Mon 1/26

1:45 pm-5:41 pm

Nonstop6h 56m

$409

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

Fri 12/12

5:23 pm-2:45 pm

1 stop18h 22m

Panama City Tocumen Intl

Mon 12/15

8:55 am-6:21 pm

1 stop12h 26m

$424

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

Fri 12/12

7:00 pm-5:07 pm

2 stops19h 07m

Panama City Tocumen Intl

Mon 12/15

11:35 am-10:30 pm

2 stops13h 55m

$428

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

Wed 1/7

8:00 am-7:38 pm

1 stop8h 38m

Panama City Tocumen Intl

Wed 1/21

4:41 pm-11:05 am

1 stop21h 24m

$433

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

Sun 1/11

8:16 pm-5:20 am

Nonstop6h 04m

Panama City Tocumen Intl

Sun 2/8

1:15 pm-5:13 pm

Nonstop6h 58m

$434

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

Fri 12/5

5:23 pm-2:45 pm

1 stop18h 22m

Panama City Tocumen Intl

Mon 12/15

11:35 am-7:56 pm

1 stop11h 21m

$449

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

Wed 1/7

8:37 pm-2:45 pm

2 stops15h 08m

Panama City Tocumen Intl

Thu 1/15

4:41 pm-10:27 am

2 stops20h 46m

$450

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

Mon 12/29

5:10 pm-2:45 pm

1 stop18h 35m

Panama City Tocumen Intl

Mon 2/23

8:55 am-11:40 pm

2 stops17h 45m

$453

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

Sun 12/7

8:12 pm-5:20 am

Nonstop6h 08m

Panama City Tocumen Intl

Tue 12/16

1:45 pm-5:37 pm

Nonstop6h 52m

$459

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

Thu 1/8

1:51 pm-2:45 pm

1 stop21h 54m

Panama City Tocumen Intl

Thu 1/15

4:41 pm-10:27 am

2 stops20h 46m

$460

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Panama from

How to get the cheapest flight ticket from San Diego to Panama

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Panama?

The month of September is, on average, the cheapest month to fly to Panama from San Diego, with most prices found around $388. If you don’t want to visit Panama in September, then you should wait until August to fly from San Diego, when ticket prices are also cheap, with an average price of $423.

What is the cheapest day to depart on your flight to Panama?

According to our data, Wednesday is the cheapest day to fly to Panama from San Diego. The lowest ticket price found for a Wednesday departure recently was $475. Keep in mind that prices can always vary depending on your route and whether or not you are flying domestic or international. When flying out on a Saturday, the most expensive travel day of the week, you can expect to see flight prices from San Diego to Panama for around $1,200.

What is the cheapest time of day to depart on your flight to Panama?

In the evening is the cheapest time of day to fly from San Diego to Panama when you can find flight prices for as low as $491. Flying to Panama in the evening is an ideal time because this is during off-peak travel hours. In the morning is when there is more demand to fly to Panama, so prices are often more expensive at around $687 per ticket.

What is the cheapest San Diego to Panama flight route?

Fly from San Diego to Panama City Tocumen Intl for the best San Diego - Panama flight prices

How far in advance should I book a flight to Panama?

You are more likely to see cheaper flights to Panama from San Diego when booking weeks ahead of your departure date. In general, you can expect to find flights to Panama for around $545 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Panama from San Diego for as low as $364 on momondo.

What cabin class options are available on San Diego to Panama flights?

There are 3 cabin classes available to choose from on San Diego to Panama flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on San Diego to Panama flights?

You could potentially save up to 17% on your flight if you consider stops on a San Diego to Panama flight.

Cheap San Diego to Panama flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from San Diego to Panama

Best Price Found

$199

Fastest flight time

6h 02m

Direct flights

Mon, Tue, Wed, Thu and Sat

Airports in Panama

1 airport
The best one-way flight to Panama from San Diego in the past 72 hours is $199. The best round-trip flight deal from San Diego to Panama found on momondo in the last 72 hours is $409.
The fastest flight from San Diego to Panama takes 6h 02m
Direct flights go from San Diego to Panama on Monday, Tuesday, Wednesday, Thursday and Saturday. There are no airlines offering direct flights.
There is 1 airport near Panama: Panama City Tocumen Intl (PTY)
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  • When did momondo last update prices for flights from San Diego Airport to Panama?

    Prices for flights from San Diego Airport to Panama refresh daily.

  • How many operators does momondo search for flights from San Diego Airport to Panama?

  • How old do you have to be to fly from San Diego Airport to Panama?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from San Diego Airport to Panama.

  • What documentation or ID do you need to fly to Panama?

    The travel and health documents required for your trip to Panama can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Panama. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular plane model from San Diego to Panama?

Best airlines flying from San Diego to Panama

Compare and see reviews for airlines that fly from San Diego to Panama with momondo
Airline
Rating
Free Cancellation
Price
Copa AirlinesPriceFrom $332Free CancellationRating
7.6
1,568 reviews
Search Copa Airlines flights
United AirlinesPriceFrom $355Free CancellationRating
7.4
9,043 reviews
Search United Airlines flights
DeltaPriceFrom $355Free CancellationRating
7.9
7,998 reviews
Search Delta flights
American AirlinesPriceFrom $489Free CancellationRating
7.2
11,039 reviews
Search American Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from San Diego to Panama?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from San Diego to Panama. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from San Diego to Panama with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Panama from San Diego with this policy.

How can momondo help me find flights from San Diego to Panama?

Once all potential San Diego to Panama flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from San Diego to Panama right now. Can momondo alert me if prices change?

If you are not ready to book a flight from San Diego to Panama now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Panama and let you know when they change.

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