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Cheap flights from Rome to Des Moines from $522

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Rome to Des Moines departing on 6/6. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Rome to Des Moines

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
10:00 am - 12:07 am
FCO
-
DSM
21h 07m
2 stops
American Airlines Logo
2:37 pm - 4:55 pm
DSM
-
FCO
20h 18m
2 stops
$895American Airlines
Thu, Oct 22 - Mon, Oct 26
American Airlines Logo
10:00 am - 12:07 am
FCO
-
DSM
21h 07m
2 stops
American Airlines Logo
1:43 pm - 9:00 am
DSM
-
FCO
13h 17m
1 stop
$906American Airlines
Thu, Oct 22 - Mon, Oct 26
American Airlines Logo
6:50 am - 6:56 pm
FCO
-
DSM
19h 06m
2 stops
American Airlines Logo
6:07 pm - 4:55 pm
DSM
-
FCO
16h 48m
2 stops
$907American Airlines
Thu, Oct 22 - Mon, Oct 26
American Airlines Logo
12:15 pm - 9:44 pm
FCO
-
DSM
16h 29m
2 stops
American Airlines Logo
6:07 pm - 7:35 pm
DSM
-
FCO
19h 28m
2 stops
$912American Airlines
Thu, Oct 22 - Mon, Oct 26
American Airlines Logo
12:15 pm - 9:44 pm
FCO
-
DSM
16h 29m
2 stops
American Airlines Logo
1:43 pm - 9:00 am
DSM
-
FCO
13h 17m
1 stop
$923American Airlines
Thu, Oct 22 - Mon, Oct 26
British Airways Logo
6:50 am - 7:03 pm
FCO
-
DSM
19h 13m
2 stops
British Airways Logo
7:05 pm - 4:55 pm
DSM
-
FCO
14h 50m
2 stops
$927British Airways
Thu, Aug 13 - Wed, Nov 11
American Airlines Logo
11:05 am - 9:44 pm
FCO
-
DSM
17h 39m
1 stop
American Airlines Logo
2:37 pm - 12:50 pm
DSM
-
FCO
16h 13m
2 stops
$937American Airlines
Thu, Oct 22 - Mon, Oct 26
American Airlines Logo
11:05 am - 9:44 pm
FCO
-
DSM
17h 39m
1 stop
American Airlines Logo
1:43 pm - 9:00 am
DSM
-
FCO
13h 17m
1 stop
$952American Airlines
Thu, Oct 22 - Mon, Oct 26
Delta Logo
6:30 am - 5:48 pm
FCO
-
DSM
18h 18m
2 stops
Delta Logo
2:15 pm - 11:20 am
DSM
-
FCO
14h 05m
1 stop
$992Delta
Thu, Aug 13 - Wed, Nov 11
KLM Logo
1:10 pm - 5:48 pm
FCO
-
DSM
35h 38m
1 stop
KLM Logo
11:04 am - 8:15 am
DSM
-
FCO
14h 11m
1 stop
$999KLM
Thu, Aug 13 - Wed, Nov 11

Delta flights from Rome to Des Moines

Our best Delta deals on Rome to Des Moines flight tickets
Delta
Aug 13
FCO6:30 amRome Fiumicino
18h 18m
2 stops
DSM5:48 pmDes Moines
Nov 11
DSM2:15 pmDes Moines
14h 05m
1 stop
FCO11:20 amRome Fiumicino
$992
Delta
Jun 26
FCO6:30 amRome Fiumicino
21h 11m
2 stops
DSM8:41 pmDes Moines
Jul 3
DSM6:03 pmDes Moines
16h 27m
2 stops
FCO5:30 pmRome Fiumicino
$1,094
Delta
Jun 26
FCO6:30 amRome Fiumicino
21h 11m
2 stops
DSM8:41 pmDes Moines
Jul 3
DSM11:42 amDes Moines
16h 08m
1 stop
FCO10:50 amRome Fiumicino
$1,098

KLM flights from Rome to Des Moines

Our best KLM deals on Rome to Des Moines flight tickets
KLM
Aug 13
FCO1:10 pmRome Fiumicino
35h 38m
1 stop
DSM5:48 pmDes Moines
Nov 11
DSM11:04 amDes Moines
14h 11m
1 stop
FCO8:15 amRome Fiumicino
$999
KLM
Jun 26
FCO9:00 amRome Fiumicino
18h 41m
1 stop
DSM8:41 pmDes Moines
Jul 3
DSM11:42 amDes Moines
12h 53m
1 stop
FCO7:35 amRome Fiumicino
$1,150
KLM
Jun 14
FCO2:45 pmRome Fiumicino
30h 20m
1 stop
DSM2:05 pmDes Moines
Jun 19
DSM10:24 amDes Moines
17h 36m
1 stop
FCO11:00 amRome Fiumicino
$1,324

momondo Fare Finder

 
Customize your flight search to find flights from Rome to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated May 17, 2026.
Use the filters below to find and compare flights from Rome to Des Moines that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

RomeDes Moines

FCO - DSM

FCODSM

Rome Fiumicino

Thu 10/22

10:00 am-12:07 am

2 stops21h 07m

Des Moines

Mon 10/26

2:37 pm-4:55 pm

2 stops20h 18m

$895

RomeDes Moines

FCO - DSM

FCODSM

Rome Fiumicino

Thu 10/22

10:00 am-12:07 am

2 stops21h 07m

Des Moines

Mon 10/26

1:43 pm-9:00 am

1 stop13h 17m

$906

RomeDes Moines

FCO - DSM

FCODSM

Rome Fiumicino

Thu 10/22

6:50 am-6:56 pm

2 stops19h 06m

Des Moines

Mon 10/26

6:07 pm-4:55 pm

2 stops16h 48m

$907

RomeDes Moines

FCO - DSM

FCODSM

Rome Fiumicino

Thu 10/22

12:15 pm-9:44 pm

2 stops16h 29m

Des Moines

Mon 10/26

6:07 pm-7:35 pm

2 stops19h 28m

$912
Quickest round-trip

RomeDes Moines

FCO - DSM

FCODSM

Rome Fiumicino

Thu 10/22

12:15 pm-9:44 pm

2 stops16h 29m

Des Moines

Mon 10/26

1:43 pm-9:00 am

1 stop13h 17m

$923

RomeDes Moines

FCO - DSM

FCODSM

Rome Fiumicino

Thu 8/13

6:50 am-7:03 pm

2 stops19h 13m

Des Moines

Wed 11/11

7:05 pm-4:55 pm

2 stops14h 50m

$927

RomeDes Moines

FCO - DSM

FCODSM

Rome Fiumicino

Thu 10/22

11:05 am-9:44 pm

1 stop17h 39m

Des Moines

Mon 10/26

2:37 pm-12:50 pm

2 stops16h 13m

$937

RomeDes Moines

FCO - DSM

FCODSM

Rome Fiumicino

Thu 10/22

11:05 am-9:44 pm

1 stop17h 39m

Des Moines

Mon 10/26

1:43 pm-9:00 am

1 stop13h 17m

$952

RomeDes Moines

FCO - DSM

FCODSM

Rome Fiumicino

Thu 8/13

6:30 am-5:48 pm

2 stops18h 18m

Des Moines

Wed 11/11

2:15 pm-11:20 am

1 stop14h 05m

$992

RomeDes Moines

FCO - DSM

FCODSM

Rome Fiumicino

Thu 8/13

1:10 pm-5:48 pm

1 stop35h 38m

Des Moines

Wed 11/11

11:04 am-8:15 am

1 stop14h 11m

$999

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Rome to Des Moines

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Can stopping save me money on Rome to Des Moines flights?

You could potentially save up to 24% on your flight if you consider stops on a Rome to Des Moines flight.

When to book flights from Rome to Des Moines

Are you open to changing your travel dates? Check out the ideal times to fly from Rome to Des Moines according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Rome to Des Moines (ROM to DSM) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Rome to Des Moines

Fastest flight time

17h 24m

Direct flights

None
The fastest flight from Rome to Des Moines takes 17h 24m
There are no direct flights from Rome to Des Moines. There are no popular flight routes from Rome to Des Moines.
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Frequently asked questions about flying from Rome to Des Moines

  • How far is Rome to Des Moines by plane?

    Rome and Des Moines are 5055.2 mi apart from one another. 17h 24m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Rome to Des Moines Airport?

    Prices for flights from Rome to Des Moines Airport refresh daily.

  • How old do you have to be to fly from Rome to Des Moines Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Rome to Des Moines Airport.

  • What documentation or ID do you need to fly to Des Moines Airport?

    The required travel and health documents for your Des Moines Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Des Moines Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
West Des Moines
Ames
Ankeny
Altoona
Clive
Urbandale
Pella
Johnston
Newton
Osceola
Boone
Oskaloosa
Grinnell
Norwalk
Carlisle

Why use momondo?

Why should I use momondo to find a flight deal from Rome to Des Moines?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Rome to Des Moines. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Rome to Des Moines with flexible booking policies on momondo?

Yes. All flights to Des Moines from Rome on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Rome to Des Moines?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Des Moines from Rome.

I’m not ready to book a flight from Rome to Des Moines right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Des Moines from Rome. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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