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Cheap flights from Panama City, Florida to Mexico City Federal District from $327

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Panama City, Florida to Mexico City Federal District departing on 1/2. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Panama City, Florida to Mexico City Federal District

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
6:55 am - 8:35 pm
ECP
-
MEX
14h 40m1 stop
American Airlines Logo
1:20 pm - 8:22 pm
MEX
-
ECP
6h 02m1 stop
$550American Airlines
Wed, Apr 29 - Fri, May 8
American Airlines Logo
9:56 am - 6:31 pm
ECP
-
MEX
9h 35m2 stops
American Airlines Logo
11:20 pm - 3:17 pm
MEX
-
ECP
14h 57m2 stops
$555American Airlines
Wed, Apr 29 - Fri, May 8
Delta Logo
7:45 am - 6:21 pm
ECP
-
MEX
11h 36m1 stop
Delta Logo
8:40 am - 6:56 pm
MEX
-
ECP
9h 16m1 stop
$567Delta
Sun, May 3 - Tue, May 12
American Airlines Logo
6:03 pm - 12:45 pm
ECP
-
MEX
18h 42m1 stop
American Airlines Logo
6:00 am - 9:19 pm
MEX
-
ECP
15h 19m1 stop
$568American Airlines
Tue, Jan 6 - Fri, Jan 16
Delta Logo
7:45 am - 3:30 pm
ECP
-
MEX
8h 45m2 stops
Delta Logo
9:00 am - 6:56 pm
MEX
-
ECP
8h 56m2 stops
$572Delta
Sun, May 3 - Wed, May 13
American Airlines Logo
6:03 pm - 12:45 pm
ECP
-
MEX
18h 42m1 stop
American Airlines Logo
5:15 pm - 2:54 pm
MEX
-
ECP
21h 39m2 stops
$573American Airlines
Tue, Jan 6 - Fri, Jan 16
Aeromexico Logo
1:32 pm - 8:50 pm
ECP
-
MEX
7h 18m1 stop
Aeromexico Logo
8:40 am - 5:12 pm
MEX
-
ECP
8h 32m1 stop
$590Aeromexico
Sun, Jan 18 - Thu, Jan 22
Delta Logo
7:00 am - 4:55 pm
ECP
-
MEX
10h 55m2 stops
Delta Logo
9:00 am - 5:28 pm
MEX
-
ECP
7h 28m1 stop
$595Delta
Sat, Apr 4 - Sun, Apr 12
American Airlines Logo
6:03 pm - 11:30 am
ECP
-
MEX
17h 27m2 stops
American Airlines Logo
4:00 pm - 1:10 pm
MEX
-
ECP
21h 10m2 stops
$648American Airlines
Tue, Jan 6 - Fri, Jan 16
American Airlines Logo
12:40 pm - 6:35 pm
ECP
-
MEX
6h 55m1 stop
American Airlines Logo
5:00 am - 8:22 pm
MEX
-
ECP
14h 22m1 stop
$713American Airlines
Sat, Apr 4 - Sun, Apr 12

American Airlines flights from Panama City, Florida to Mexico City Federal District

Our best American Airlines deals on Panama City, Florida to Mexico City Federal District flight tickets
American Airlines
Apr 29
ECP6:55 amPanama City NW Florida Beaches
14h 40m
1 stop
MEX8:35 pmMexico City Benito Juarez
May 8
MEX1:20 pmMexico City Benito Juarez
6h 02m
1 stop
ECP8:22 pmPanama City NW Florida Beaches
$550
Find similar
American Airlines
Apr 29
ECP9:56 amPanama City NW Florida Beaches
9h 35m
2 stops
MEX6:31 pmMexico City Benito Juarez
May 8
MEX11:20 pmMexico City Benito Juarez
14h 57m
2 stops
ECP3:17 pmPanama City NW Florida Beaches
$555
Find similar
American Airlines
Jan 6
ECP6:03 pmPanama City NW Florida Beaches
18h 42m
1 stop
MEX12:45 pmMexico City Benito Juarez
Jan 16
MEX6:00 amMexico City Benito Juarez
15h 19m
1 stop
ECP9:19 pmPanama City NW Florida Beaches
$568
Find similar

Delta flights from Panama City, Florida to Mexico City Federal District

Our best Delta deals on Panama City, Florida to Mexico City Federal District flight tickets
Delta
May 3
ECP7:45 amPanama City NW Florida Beaches
11h 36m
1 stop
MEX6:21 pmMexico City Benito Juarez
May 12
MEX8:40 amMexico City Benito Juarez
9h 16m
1 stop
ECP6:56 pmPanama City NW Florida Beaches
$567
Find similar
Delta
May 3
ECP7:45 amPanama City NW Florida Beaches
8h 45m
2 stops
MEX3:30 pmMexico City Benito Juarez
May 13
MEX9:00 amMexico City Benito Juarez
8h 56m
2 stops
ECP6:56 pmPanama City NW Florida Beaches
$572
Find similar
Delta
Apr 4
ECP7:00 amPanama City NW Florida Beaches
10h 55m
2 stops
MEX4:55 pmMexico City Benito Juarez
Apr 12
MEX9:00 amMexico City Benito Juarez
7h 28m
1 stop
ECP5:28 pmPanama City NW Florida Beaches
$595
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Panama City, Florida to Mexico City Federal District that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated December 11, 2025.
Use the filters below to find and compare flights from Panama City, Florida to Mexico City Federal District that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Panama CityMexico City

ECP - MEX

ECPMEX

Panama City NW Florida Beaches

Wed 4/29

6:55 am-8:35 pm

1 stop14h 40m

Mexico City Benito Juarez

Fri 5/8

1:20 pm-8:22 pm

1 stop6h 02m

$550

Panama CityMexico City

ECP - MEX

ECPMEX

Panama City NW Florida Beaches

Wed 4/29

9:56 am-6:31 pm

2 stops9h 35m

Mexico City Benito Juarez

Fri 5/8

11:20 pm-3:17 pm

2 stops14h 57m

$555

Panama CityMexico City

ECP - MEX

ECPMEX

Panama City NW Florida Beaches

Sun 5/3

7:45 am-6:21 pm

1 stop11h 36m

Mexico City Benito Juarez

Tue 5/12

8:40 am-6:56 pm

1 stop9h 16m

$567

Panama CityMexico City

ECP - MEX

ECPMEX

Panama City NW Florida Beaches

Tue 1/6

6:03 pm-12:45 pm

1 stop18h 42m

Mexico City Benito Juarez

Fri 1/16

6:00 am-9:19 pm

1 stop15h 19m

$568

Panama CityMexico City

ECP - MEX

ECPMEX

Panama City NW Florida Beaches

Sun 5/3

7:45 am-3:30 pm

2 stops8h 45m

Mexico City Benito Juarez

Wed 5/13

9:00 am-6:56 pm

2 stops8h 56m

$572

Panama CityMexico City

ECP - MEX

ECPMEX

Panama City NW Florida Beaches

Tue 1/6

6:03 pm-12:45 pm

1 stop18h 42m

Mexico City Benito Juarez

Fri 1/16

5:15 pm-2:54 pm

2 stops21h 39m

$573

Panama CityMexico City

ECP - MEX

ECPMEX

Panama City NW Florida Beaches

Sun 1/18

1:32 pm-8:50 pm

1 stop7h 18m

Mexico City Benito Juarez

Thu 1/22

8:40 am-5:12 pm

1 stop8h 32m

$590

Panama CityMexico City

ECP - MEX

ECPMEX

Panama City NW Florida Beaches

Sat 4/4

7:00 am-4:55 pm

2 stops10h 55m

Mexico City Benito Juarez

Sun 4/12

9:00 am-5:28 pm

1 stop7h 28m

$595

Panama CityMexico City

ECP - MEX

ECPMEX

Panama City NW Florida Beaches

Tue 1/6

6:03 pm-11:30 am

2 stops17h 27m

Mexico City Benito Juarez

Fri 1/16

4:00 pm-1:10 pm

2 stops21h 10m

$648

Panama CityMexico City

ECP - MEX

ECPMEX

Panama City NW Florida Beaches

Sat 4/4

12:40 pm-6:35 pm

1 stop6h 55m

Mexico City Benito Juarez

Sun 4/12

5:00 am-8:22 pm

1 stop14h 22m

$713

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 13 resultsSorted by cheapest first
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See travel insights to Mexico City Federal District from

How to get the cheapest flight ticket from Panama City, Florida to Mexico City Federal District

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Mexico City Federal District?

If you are unable to visit Mexico City Federal District during the month of September, then departing from Panama City, Florida during the month May is also very affordable. Most momondo users find prices during this month for around $537.

What is the cheapest day to depart on your flight to Mexico City Federal District?

The cheapest day to depart on your flight to Mexico City Federal District is on a Thursday when prices can be found for as low as $574. This is often the case because there is less demand to fly during this day of the week. When flying out on a Saturday, the most expensive travel day of the week, you can expect to see flight prices from Panama City, Florida to Mexico City Federal District for around $920.

Cheap Panama City, Florida to Mexico City Federal District flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Panama City, Florida to Mexico City Federal District

Fastest flight time

7h 10m

Direct flights

None
The fastest flight from Panama City, Florida to Mexico City Federal District takes 7h 10m
There are no direct flights from Panama City, Florida to Mexico City Federal District. There are no popular flight routes from Panama City, Florida to Mexico City Federal District.
Search flight deals

  • When did momondo last update prices for flights from Panama City NW Florida Beaches Airport to Mexico City Federal District?

    Prices for flights from Panama City NW Florida Beaches Airport to Mexico City Federal District were last updated today.

  • How many operators does momondo search for flights from Panama City NW Florida Beaches Airport to Mexico City Federal District?

  • How old do you have to be to fly from Panama City NW Florida Beaches Airport to Mexico City Federal District?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Panama City NW Florida Beaches Airport to Mexico City Federal District.

  • What documentation or ID do you need to fly to Mexico City Federal District?

    The necessary travel and health documents for your Mexico City Federal District trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Best airlines flying from Panama City, Florida to Mexico City Federal District

Compare and see reviews for airlines that fly from Panama City, Florida to Mexico City Federal District with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $362Free CancellationRating
7.9
8,007 reviews
Search Delta flights
United AirlinesPriceFrom $546Free CancellationRating
7.4
9,095 reviews
Search United Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Panama City to Mexico City Federal District?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Mexico City Federal District from Panama City.

Can I find flights from Panama City to Mexico City Federal District with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Panama City to Mexico City Federal District flights to just show those with flexible booking policies.

How can momondo help me find flights from Panama City to Mexico City Federal District?

momondo provides multiple filters to help you find the best flight to Mexico City Federal District from Panama City. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Panama City to Mexico City Federal District right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Panama City to Mexico City Federal District flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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