Cheap flights from Chicago O'Hare Intl Airport to Panama from $190

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Chicago O'Hare Intl Airport to Panama departing on 1/14. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
9:23 am - 10:30 am
ORD
-
PTY
24h 07m3 stops
Multiple Airlines Logo
2:55 am - 6:16 pm
PTY
-
ORD
16h 21m2 stops
$477Multiple Airlines
Thu, Jan 22 - Wed, Jan 28
Multiple Airlines Logo
6:57 pm - 8:50 am
ORD
-
PTY
12h 53m2 stops
Multiple Airlines Logo
6:15 pm - 8:18 am
PTY
-
ORD
15h 03m1 stop
$484Multiple Airlines
Mon, Jan 19 - Mon, Jan 26
Multiple Airlines Logo
6:57 pm - 8:06 am
ORD
-
PTY
12h 09m1 stop
Multiple Airlines Logo
9:33 pm - 9:39 am
PTY
-
ORD
13h 06m1 stop
$495Multiple Airlines
Mon, Feb 9 - Tue, Feb 17
Multiple Airlines Logo
6:57 pm - 8:50 am
ORD
-
PTY
12h 53m2 stops
Multiple Airlines Logo
6:34 pm - 8:18 am
PTY
-
ORD
14h 44m1 stop
$498Multiple Airlines
Fri, Jan 23 - Fri, Jan 30
Multiple Airlines Logo
7:20 am - 8:50 am
ORD
-
PTY
24h 30m2 stops
Multiple Airlines Logo
2:55 am - 9:03 pm
PTY
-
ORD
19h 08m2 stops
$500Multiple Airlines
Thu, Jan 22 - Wed, Jan 28
United Airlines Logo
5:45 am - 5:31 pm
ORD
-
DAV
10h 46m2 stops
United Airlines Logo
9:48 am - 7:46 am
DAV
-
ORD
22h 58m2 stops
$1,012United Airlines
Tue, Feb 17 - Thu, Feb 19
United Airlines Logo
7:34 am - 5:31 pm
ORD
-
DAV
8h 57m1 stop
United Airlines Logo
9:48 am - 12:26 am
DAV
-
ORD
15h 38m2 stops
$1,181United Airlines
Fri, Feb 20 - Wed, Feb 25
United Airlines Logo
5:45 am - 5:31 pm
ORD
-
DAV
10h 46m2 stops
United Airlines Logo
9:48 am - 12:04 am
DAV
-
ORD
15h 16m1 stop
$1,183United Airlines
Tue, Feb 17 - Thu, Feb 19
United Airlines Logo
9:05 pm - 5:31 pm
ORD
-
DAV
19h 26m2 stops
United Airlines Logo
9:48 am - 12:26 am
DAV
-
ORD
15h 38m2 stops
$1,252United Airlines
Sun, Mar 1 - Sat, Mar 7
Copa Airlines Logo
2:22 pm - 9:04 am
ORD
-
DAV
17h 42m1 stop
Copa Airlines Logo
8:32 am - 12:31 pm
DAV
-
ORD
28h 59m1 stop
$1,270Copa Airlines
Sun, Mar 1 - Sat, Mar 7

United Airlines flights from Chicago O'Hare Intl Airport to Panama

Our best United Airlines deals on Chicago O'Hare Intl Airport to Panama flight tickets
United Airlines
Dec 21
ORD9:23 pmChicago O'Hare Intl
18h 44m
1 stop
PTY5:07 pmPanama City Tocumen Intl
Dec 31
PTY11:55 pmPanama City Tocumen Intl
10h 15m
1 stop
ORD9:10 amChicago O'Hare Intl
United Airlines
Dec 17
ORD7:35 amChicago O'Hare Intl
11h 03m
1 stop
PTY7:38 pmPanama City Tocumen Intl
Dec 24
PTY4:41 pmPanama City Tocumen Intl
8h 33m
1 stop
ORD12:14 amChicago O'Hare Intl
United Airlines
Dec 21
ORD8:05 pmChicago O'Hare Intl
20h 02m
1 stop
PTY5:07 pmPanama City Tocumen Intl
Dec 28
PTY8:55 amPanama City Tocumen Intl
10h 50m
1 stop
ORD6:45 pmChicago O'Hare Intl

Avianca flights from Chicago O'Hare Intl Airport to Panama

Our best Avianca deals on Chicago O'Hare Intl Airport to Panama flight tickets
Avianca
Feb 5
ORD10:20 pmChicago O'Hare Intl
17h 35m
1 stop
PTY4:55 pmPanama City Tocumen Intl
Feb 7
PTY2:55 amPanama City Tocumen Intl
18h 25m
1 stop
ORD8:20 pmChicago O'Hare Intl
Avianca
Jan 6
ORD4:10 pmChicago O'Hare Intl
17h 20m
1 stop
PTY10:30 amPanama City Tocumen Intl
Jan 20
PTY2:55 amPanama City Tocumen Intl
18h 25m
1 stop
ORD8:20 pmChicago O'Hare Intl
Avianca
Jan 3
ORD4:10 pmChicago O'Hare Intl
17h 20m
1 stop
PTY10:30 amPanama City Tocumen Intl
Jan 31
PTY2:55 amPanama City Tocumen Intl
18h 25m
1 stop
ORD8:20 pmChicago O'Hare Intl

momondo Fare Finder

 
Customize your flight search to find flights from Chicago O'Hare Intl Airport to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated December 11, 2025.
Use the filters below to find and compare flights from Chicago O'Hare Intl Airport to Panama that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

ChicagoPanama City

ORD - PTY

ORDPTY

Chicago O'Hare Intl

Thu 1/22

9:23 am-10:30 am

3 stops24h 07m

Panama City Tocumen Intl

Wed 1/28

2:55 am-6:16 pm

2 stops16h 21m

$477

ChicagoPanama City

ORD - PTY

ORDPTY

Chicago O'Hare Intl

Mon 1/19

6:57 pm-8:50 am

2 stops12h 53m

Panama City Tocumen Intl

Mon 1/26

6:15 pm-8:18 am

1 stop15h 03m

$484

ChicagoPanama City

ORD - PTY

ORDPTY

Chicago O'Hare Intl

Mon 2/9

6:57 pm-8:06 am

1 stop12h 09m

Panama City Tocumen Intl

Tue 2/17

9:33 pm-9:39 am

1 stop13h 06m

$495

ChicagoPanama City

ORD - PTY

ORDPTY

Chicago O'Hare Intl

Fri 1/23

6:57 pm-8:50 am

2 stops12h 53m

Panama City Tocumen Intl

Fri 1/30

6:34 pm-8:18 am

1 stop14h 44m

$498

ChicagoPanama City

ORD - PTY

ORDPTY

Chicago O'Hare Intl

Thu 1/22

7:20 am-8:50 am

2 stops24h 30m

Panama City Tocumen Intl

Wed 1/28

2:55 am-9:03 pm

2 stops19h 08m

$500

ChicagoDavid

ORD - DAV

ORDDAV

Chicago O'Hare Intl

Tue 2/17

5:45 am-5:31 pm

2 stops10h 46m

David Enrique Malek

Thu 2/19

9:48 am-7:46 am

2 stops22h 58m

$1,012

ChicagoDavid

ORD - DAV

ORDDAV

Chicago O'Hare Intl

Fri 2/20

7:34 am-5:31 pm

1 stop8h 57m

David Enrique Malek

Wed 2/25

9:48 am-12:26 am

2 stops15h 38m

$1,181

ChicagoDavid

ORD - DAV

ORDDAV

Chicago O'Hare Intl

Tue 2/17

5:45 am-5:31 pm

2 stops10h 46m

David Enrique Malek

Thu 2/19

9:48 am-12:04 am

1 stop15h 16m

$1,183

ChicagoDavid

ORD - DAV

ORDDAV

Chicago O'Hare Intl

Sun 3/1

9:05 pm-5:31 pm

2 stops19h 26m

David Enrique Malek

Sat 3/7

9:48 am-12:26 am

2 stops15h 38m

$1,252

ChicagoDavid

ORD - DAV

ORDDAV

Chicago O'Hare Intl

Sun 3/1

2:22 pm-9:04 am

1 stop17h 42m

David Enrique Malek

Sat 3/7

8:32 am-12:31 pm

1 stop28h 59m

$1,270

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Panama from

How to get the cheapest flight ticket from Chicago O'Hare Intl Airport to Panama

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Panama?

The month of October is, on average, the cheapest month to fly to Panama from Chicago O'Hare Intl Airport, with most prices found around $480. If you don’t want to visit Panama in October, then you should wait until September to fly from Chicago O'Hare Intl Airport, when ticket prices are also cheap, with an average price of $521.

What is the cheapest day to depart on your flight to Panama?

According to our data, Tuesday is the cheapest day to fly to Panama from Chicago O'Hare Intl Airport. The lowest ticket price found for a Tuesday departure recently was $528. Keep in mind that prices can always vary depending on your route and whether or not you are flying domestic or international. When flying out on a Sunday, the most expensive travel day of the week, you can expect to see flight prices from Chicago O'Hare Intl Airport to Panama for around $587.

What is the cheapest time of day to depart on your flight to Panama?

In the evening is the cheapest time of day to fly from Chicago O'Hare Intl Airport to Panama when you can find flight prices for as low as $499. Flying to Panama in the evening is an ideal time because this is during off-peak travel hours. In the morning is when there is more demand to fly to Panama, so prices are often more expensive at around $577 per ticket.

What is the cheapest Chicago O'Hare Intl to Panama flight route?

Fly from Chicago O'Hare Intl to Panama City Tocumen Intl for the best Chicago O'Hare Intl - Panama flight prices

How far in advance should I book a flight to Panama?

You are more likely to see cheaper flights to Panama from Chicago O'Hare Intl Airport when booking weeks ahead of your departure date. In general, you can expect to find flights to Panama for around $584 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Panama from Chicago O'Hare Intl Airport for as low as $538 on momondo.

What cabin class options are available on Chicago O'Hare Intl to Panama flights?

There are 3 cabin classes available to choose from on Chicago O'Hare Intl to Panama flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Chicago O'Hare Intl Airport to Panama flights?

You could potentially save up to 34% on your flight if you consider stops on a Chicago O'Hare Intl Airport to Panama flight.

Cheap Chicago O'Hare Intl Airport to Panama flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Chicago O'Hare Intl Airport to Panama

Best Price Found

$207

Fastest flight time

5h 13m

Direct flights

Every day

Airports in Panama

21 airports
The best one-way flight to Panama from Chicago O'Hare Intl Airport in the past 72 hours is $207. The best round-trip flight deal from Chicago O'Hare Intl Airport to Panama found on momondo in the last 72 hours is $430.
The fastest flight from Chicago O'Hare Intl Airport to Panama takes 5h 13m
Direct flights go from Chicago O'Hare Intl Airport to Panama every day.
There are 21 airports in Panama. From Chicago O'Hare Intl Airport there are direct flights to Panama City Tocumen Intl (PTY).
  • When did momondo last update prices for flights from Chicago O'Hare Intl Airport to Panama?

    Prices for flights from Chicago O'Hare Intl Airport to Panama are updated daily.

  • How many operators does momondo search for flights from Chicago O'Hare Intl Airport to Panama?

  • How old do you have to be to fly from Chicago O'Hare Intl Airport to Panama?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Chicago O'Hare Intl Airport to Panama.

  • What documentation or ID do you need to fly to Panama?

    The travel and health documents you'll need for your trip to Panama may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Panama. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from Chicago O'Hare Intl Airport to Panama?

Best airlines flying from Chicago O'Hare Intl Airport to Panama

Compare and see reviews for airlines that fly from Chicago O'Hare Intl Airport to Panama with momondo
Airline
Rating
Free Cancellation
Price
AviancaPriceFrom $358Free CancellationRating
6.6
2,478 reviews
Search Avianca flights
Copa AirlinesPriceFrom $464Free CancellationRating
7.6
1,558 reviews
Search Copa Airlines flights
United AirlinesPriceFrom $479Free CancellationRating
7.4
9,095 reviews
Search United Airlines flights
DeltaPriceFrom $479Free CancellationRating
7.9
8,008 reviews
Search Delta flights
American AirlinesPriceFrom $589Free CancellationRating
7.2
11,048 reviews
Search American Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Chicago to Panama?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Chicago to Panama. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Chicago to Panama with flexible booking policies on momondo?

momondo does allow users to show only those flights to Panama from Chicago which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Chicago to Panama?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Chicago to Panama.

I’m not ready to book a flight from Chicago to Panama right now. Can momondo alert me if prices change?

Price alerts on flights to Panama from Chicago are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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1 adult
Sat 1/10
Sat 1/17

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