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Cheap flights from Chicago O'Hare Intl Airport to Panama from $193

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Chicago O'Hare Intl Airport to Panama departing on 11/30. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Chicago O'Hare Intl Airport to Panama

Cheap round-trip flights

Enter your travel dates to find the best prices.
Copa Airlines Logo
2:07 pm - 8:35 pmORD-PTY
5h 28mnonstop
Copa Airlines Logo
7:20 pm - 12:05 amPTY-ORD
5h 45mnonstop
$451Copa Airlines
Find Deal
Mon, Dec 1 - Thu, Dec 4
Multiple Airlines Logo
10:20 pm - 2:00 pmORD-PTY
14h 40m1 stop
Multiple Airlines Logo
11:25 am - 12:09 amPTY-ORD
13h 44m2 stops
$454Multiple Airlines
Find Deal
Wed, Dec 3 - Wed, Dec 10
Avianca Logo
4:10 pm - 10:30 amORD-PTY
17h 20m1 stop
Avianca Logo
2:55 am - 8:20 pmPTY-ORD
18h 25m1 stop
$463Avianca
Find Deal
Thu, Jan 8 - Wed, Jan 14
Delta Logo
5:33 am - 1:55 pmORD-PTY
7h 22m1 stop
Delta Logo
3:20 pm - 11:57 pmPTY-ORD
9h 37m1 stop
$466Delta
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Sun, Jan 18 - Fri, Jan 23
Delta Logo
6:45 am - 7:59 pmORD-PTY
12h 14m2 stops
Delta Logo
3:46 pm - 10:46 pmPTY-ORD
8h 00m1 stop
$470Delta
Find Deal
Fri, Dec 5 - Wed, Dec 10
American Airlines Logo
7:30 pm - 1:27 pmORD-PTY
16h 57m1 stop
American Airlines Logo
4:50 pm - 9:05 amPTY-ORD
17h 15m1 stop
$471American Airlines
Find Deal
Thu, Feb 5 - Sun, Feb 8
American Airlines Logo
7:55 pm - 1:27 pmORD-PTY
16h 32m2 stops
American Airlines Logo
4:50 pm - 8:38 amPTY-ORD
16h 48m2 stops
$475American Airlines
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Thu, Feb 5 - Sun, Feb 8
Avianca Logo
10:20 pm - 2:00 pmORD-PTY
14h 40m1 stop
Avianca Logo
2:55 am - 8:20 pmPTY-ORD
18h 25m1 stop
$479Avianca
Find Deal
Wed, Feb 25 - Sat, Feb 28
United Airlines Logo
9:05 pm - 5:31 pmORD-DAV
19h 26m2 stops
United Airlines Logo
9:48 am - 5:08 pmDAV-ORD
32h 20m2 stops
$1,003United Airlines
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Fri, Feb 13 - Mon, Feb 16
United Airlines Logo
10:35 am - 9:09 amORD-DAV
21h 34m2 stops
United Airlines Logo
9:50 am - 10:56 pmDAV-ORD
38h 06m2 stops
$1,066United Airlines
Find Deal
Tue, Dec 2 - Tue, Dec 9

Avianca flights from Chicago O'Hare Intl Airport to Panama

Our best Avianca deals on Chicago O'Hare Intl Airport to Panama flight tickets
Avianca
Jan 8
ORD4:10 pmChicago O'Hare Intl
17h 20m
1 stop
PTY10:30 amPanama City Tocumen Intl
Jan 14
PTY2:55 amPanama City Tocumen Intl
18h 25m
1 stop
ORD8:20 pmChicago O'Hare Intl
$463
Find similar
Avianca
Feb 25
ORD10:20 pmChicago O'Hare Intl
14h 40m
1 stop
PTY2:00 pmPanama City Tocumen Intl
Feb 28
PTY2:55 amPanama City Tocumen Intl
18h 25m
1 stop
ORD8:20 pmChicago O'Hare Intl
$479
Find similar
Avianca
Nov 12
ORD10:20 pmChicago O'Hare Intl
14h 40m
1 stop
PTY2:00 pmPanama City Tocumen Intl
Nov 25
PTY2:55 amPanama City Tocumen Intl
18h 25m
1 stop
ORD8:20 pmChicago O'Hare Intl
$487
Find similar

Delta flights from Chicago O'Hare Intl Airport to Panama

Our best Delta deals on Chicago O'Hare Intl Airport to Panama flight tickets
Delta
Nov 10
ORD8:02 pmChicago O'Hare Intl
17h 10m
1 stop
PTY2:12 pmPanama City Tocumen Intl
Nov 16
PTY3:37 pmPanama City Tocumen Intl
19h 24m
2 stops
ORD10:01 amChicago O'Hare Intl
$455
Find similar
Delta
Jan 18
ORD5:33 amChicago O'Hare Intl
7h 22m
1 stop
PTY1:55 pmPanama City Tocumen Intl
Jan 23
PTY3:20 pmPanama City Tocumen Intl
9h 37m
1 stop
ORD11:57 pmChicago O'Hare Intl
$466
Find similar
Delta
Nov 11
ORD5:23 amChicago O'Hare Intl
7h 49m
1 stop
PTY2:12 pmPanama City Tocumen Intl
Nov 16
PTY8:05 amPanama City Tocumen Intl
13h 24m
2 stops
ORD8:29 pmChicago O'Hare Intl
$470
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Chicago O'Hare Intl Airport to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated November 4, 2025.
Use the filters below to find and compare flights from Chicago O'Hare Intl Airport to Panama that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

ChicagoPanama City

ORD - PTY

ORDPTY

Chicago O'Hare Intl

Mon 12/1

2:07 pm-8:35 pm

Nonstop5h 28m

Panama City Tocumen Intl

Thu 12/4

7:20 pm-12:05 am

Nonstop5h 45m

$451

ChicagoPanama City

ORD - PTY

ORDPTY

Chicago O'Hare Intl

Wed 12/3

10:20 pm-2:00 pm

1 stop14h 40m

Panama City Tocumen Intl

Wed 12/10

11:25 am-12:09 am

2 stops13h 44m

$454

ChicagoPanama City

ORD - PTY

ORDPTY

Chicago O'Hare Intl

Thu 1/8

4:10 pm-10:30 am

1 stop17h 20m

Panama City Tocumen Intl

Wed 1/14

2:55 am-8:20 pm

1 stop18h 25m

$463

ChicagoPanama City

ORD - PTY

ORDPTY

Chicago O'Hare Intl

Sun 1/18

5:33 am-1:55 pm

1 stop7h 22m

Panama City Tocumen Intl

Fri 1/23

3:20 pm-11:57 pm

1 stop9h 37m

$466

ChicagoPanama City

ORD - PTY

ORDPTY

Chicago O'Hare Intl

Fri 12/5

6:45 am-7:59 pm

2 stops12h 14m

Panama City Tocumen Intl

Wed 12/10

3:46 pm-10:46 pm

1 stop8h 00m

$470

ChicagoPanama City

ORD - PTY

ORDPTY

Chicago O'Hare Intl

Thu 2/5

7:30 pm-1:27 pm

1 stop16h 57m

Panama City Tocumen Intl

Sun 2/8

4:50 pm-9:05 am

1 stop17h 15m

$471

ChicagoPanama City

ORD - PTY

ORDPTY

Chicago O'Hare Intl

Thu 2/5

7:55 pm-1:27 pm

2 stops16h 32m

Panama City Tocumen Intl

Sun 2/8

4:50 pm-8:38 am

2 stops16h 48m

$475

ChicagoPanama City

ORD - PTY

ORDPTY

Chicago O'Hare Intl

Wed 2/25

10:20 pm-2:00 pm

1 stop14h 40m

Panama City Tocumen Intl

Sat 2/28

2:55 am-8:20 pm

1 stop18h 25m

$479

ChicagoDavid

ORD - DAV

ORDDAV

Chicago O'Hare Intl

Fri 2/13

9:05 pm-5:31 pm

2 stops19h 26m

David Enrique Malek

Mon 2/16

9:48 am-5:08 pm

2 stops32h 20m

$1,003

ChicagoDavid

ORD - DAV

ORDDAV

Chicago O'Hare Intl

Tue 12/2

10:35 am-9:09 am

2 stops21h 34m

David Enrique Malek

Tue 12/9

9:50 am-10:56 pm

2 stops38h 06m

$1,066

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Panama from

How to get the cheapest flight ticket from Chicago O'Hare Intl Airport to Panama

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Panama?

The month of November is, on average, the cheapest month to fly to Panama from Chicago O'Hare Intl Airport, with most prices found around $499. If you don’t want to visit Panama in November, then you should wait until September to fly from Chicago O'Hare Intl Airport, when ticket prices are also cheap, with an average price of $521.

What is the cheapest day to depart on your flight to Panama?

According to our data, Tuesday is the cheapest day to fly to Panama from Chicago O'Hare Intl Airport. The lowest ticket price found for a Tuesday departure recently was $530. Keep in mind that prices can always vary depending on your route and whether or not you are flying domestic or international. When flying out on a Sunday, the most expensive travel day of the week, you can expect to see flight prices from Chicago O'Hare Intl Airport to Panama for around $606.

What is the cheapest time of day to depart on your flight to Panama?

In the evening is the cheapest time of day to fly from Chicago O'Hare Intl Airport to Panama when you can find flight prices for as low as $505. Flying to Panama in the evening is an ideal time because this is during off-peak travel hours. At noon is when there is more demand to fly to Panama, so prices are often more expensive at around $592 per ticket.

What is the cheapest Chicago O'Hare Intl to Panama flight route?

Fly from Chicago O'Hare Intl to Panama City Tocumen Intl for the best Chicago O'Hare Intl - Panama flight prices

How far in advance should I book a flight to Panama?

You are more likely to see cheaper flights to Panama from Chicago O'Hare Intl Airport when booking weeks ahead of your departure date. In general, you can expect to find flights to Panama for around $573 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Panama from Chicago O'Hare Intl Airport for as low as $499 on momondo.

What cabin class options are available on Chicago O'Hare Intl to Panama flights?

There are 3 cabin classes available to choose from on Chicago O'Hare Intl to Panama flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Chicago O'Hare Intl Airport to Panama flights?

You could potentially save up to 57% on your flight if you consider stops on a Chicago O'Hare Intl Airport to Panama flight.

Cheap Chicago O'Hare Intl Airport to Panama flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Chicago O'Hare Intl Airport to Panama

Best Price Found

$170

Fastest flight time

5h 13m

Direct flights

Every day

Airports in Panama

1 airport
The best one-way flight to Panama from Chicago O'Hare Intl Airport in the past 72 hours is $170. The best round-trip flight deal from Chicago O'Hare Intl Airport to Panama found on momondo in the last 72 hours is $463.
The fastest flight from Chicago O'Hare Intl Airport to Panama takes 5h 13m
Direct flights go from Chicago O'Hare Intl Airport to Panama every day.
There is 1 airport near Panama: Panama City Tocumen Intl (PTY)
Search flight deals

  • When did momondo last update prices for flights from Chicago O'Hare Intl Airport to Panama?

    Prices for flights from Chicago O'Hare Intl Airport to Panama are updated daily.

  • How many operators does momondo search for flights from Chicago O'Hare Intl Airport to Panama?

  • How old do you have to be to fly from Chicago O'Hare Intl Airport to Panama?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Chicago O'Hare Intl Airport to Panama.

  • What documentation or ID do you need to fly to Panama?

    The travel and health documents you'll need for your trip to Panama may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Panama. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from Chicago O'Hare Intl Airport to Panama?

Best airlines flying from Chicago O'Hare Intl Airport to Panama

Compare and see reviews for airlines that fly from Chicago O'Hare Intl Airport to Panama with momondo
Airline
Rating
Free Cancellation
Price
AviancaPriceFrom $334Free CancellationRating
6.6
2,470 reviews
Search Avianca flights
Copa AirlinesPriceFrom $464Free CancellationRating
7.6
1,561 reviews
Search Copa Airlines flights
United AirlinesPriceFrom $479Free CancellationRating
7.4
8,998 reviews
Search United Airlines flights
DeltaPriceFrom $479Free CancellationRating
7.9
8,002 reviews
Search Delta flights
American AirlinesPriceFrom $589Free CancellationRating
7.2
11,038 reviews
Search American Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Chicago to Panama?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Chicago to Panama. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Chicago to Panama with flexible booking policies on momondo?

momondo does allow users to show only those flights to Panama from Chicago which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Chicago to Panama?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Chicago to Panama.

I’m not ready to book a flight from Chicago to Panama right now. Can momondo alert me if prices change?

Price alerts on flights to Panama from Chicago are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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