What airlines fly to Panama?

American Airlines, Delta and United Airlines are the top three most popular airlines that fly to Panama from Myrtle Beach according to our data. American Airlines is the first choice among our users, with 62% of people opting to fly with this airline when traveling to Panama. Keep in mind that there are 3 different airlines that fly to Panama on a routine basis, so you have a few additional options to choose from.

When did momondo last update prices for flights from Myrtle Beach Intl Airport to Panama?

Prices for flights from Myrtle Beach Intl Airport to Panama refresh daily.

How many operators does momondo search for flights from Myrtle Beach Intl Airport to Panama?

The number of operators available for flights from Myrtle Beach Intl Airport to Panama is 1 as of October 2025.

How old do you have to be to fly from Myrtle Beach Intl Airport to Panama?

Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Myrtle Beach Intl Airport to Panama.

What documentation or ID do you need to fly to Panama?

The travel and health documents you'll need for your trip to Panama may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Panama. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

$440 Cheap Flights from Myrtle Beach to Panama in 2025/26

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4:03 pm - 1:47 pmMYR-PTY

21h 44m2 stops

3:50 pm - 5:10 pmPTY-MYR

24h 20m2 stops

$440American Airlines

Find Deal

Mon, Dec 15 - Thu, Mar 12

6:15 am - 12:40 amMYR-PTY

18h 25m2 stops

2:55 am - 8:03 pmPTY-MYR

17h 08m2 stops

$638Multiple Airlines

Find Deal

Fri, Nov 21 - Thu, Nov 27

5:03 am - 1:43 pmMYR-PTY

8h 40m2 stops

2:43 pm - 11:08 amPTY-MYR

20h 25m2 stops

$690American Airlines

Find Deal

Fri, Nov 21 - Fri, Nov 28

6:15 am - 10:30 amMYR-PTY

28h 15m3 stops

2:55 am - 11:54 pmPTY-MYR

20h 59m3 stops

$698Multiple Airlines

Find Deal

Fri, Nov 21 - Thu, Nov 27

6:15 am - 10:30 amMYR-PTY

28h 15m3 stops

9:45 am - 11:54 pmPTY-MYR

14h 09m2 stops

$736Multiple Airlines

Find Deal

Fri, Nov 21 - Fri, Nov 28

2:46 pm - 1:00 amMYR-PTY

34h 14m2 stops

12:03 pm - 11:54 pmPTY-MYR

11h 51m1 stop

$773Multiple Airlines

Find Deal

Fri, Nov 21 - Fri, Nov 28

2:46 pm - 8:19 pmMYR-PTY

29h 33m1 stop

2:55 am - 8:03 pmPTY-MYR

17h 08m2 stops

$787Multiple Airlines

Find Deal

Fri, Nov 21 - Thu, Nov 27

6:00 am - 2:21 pmMYR-PTY

8h 21m1 stop

2:20 pm - 11:35 pmPTY-MYR

8h 15m1 stop

$798Delta

Find Deal

Mon, Dec 15 - Thu, Mar 12

6:00 am - 2:21 pmMYR-PTY

8h 21m1 stop

2:20 pm - 11:35 pmPTY-MYR

8h 15m1 stop

$808Delta

Find Deal

Mon, Dec 15 - Thu, Mar 12

6:15 am - 10:30 amMYR-PTY

28h 15m3 stops

2:55 pm - 8:03 pmPTY-MYR

29h 08m3 stops

$831Multiple Airlines

Find Deal

Fri, Nov 21 - Fri, Nov 28

Delta flights from Myrtle Beach to Panama

Our best Delta deals on Myrtle Beach to Panama flight tickets

Delta

Dec 15

MYR6:00 amMyrtle Beach Intl

8h 21m

1 stop

PTY2:21 pmPanama City Tocumen Intl

Mar 12

PTY2:20 pmPanama City Tocumen Intl

8h 15m

1 stop

MYR11:35 pmMyrtle Beach Intl

$798

Find similar

Delta

Dec 15

MYR6:00 amMyrtle Beach Intl

8h 21m

1 stop

PTY2:21 pmPanama City Tocumen Intl

Mar 12

PTY2:20 pmPanama City Tocumen Intl

8h 15m

1 stop

MYR11:35 pmMyrtle Beach Intl

$808

Find similar

American Airlines flights from Myrtle Beach to Panama

Our best American Airlines deals on Myrtle Beach to Panama flight tickets

American Airlines

Dec 15

MYR4:03 pmMyrtle Beach Intl

21h 44m

2 stops

PTY1:47 pmPanama City Tocumen Intl

Mar 12

PTY3:50 pmPanama City Tocumen Intl

24h 20m

2 stops

MYR5:10 pmMyrtle Beach Intl

$440

Find similar

American Airlines

Nov 21

MYR5:03 amMyrtle Beach Intl

8h 40m

2 stops

PTY1:43 pmPanama City Tocumen Intl

Nov 28

PTY2:43 pmPanama City Tocumen Intl

20h 25m

2 stops

MYR11:08 amMyrtle Beach Intl

$690

Find similar

Fly from

Fly to

Route

Depart

Return

Price

Myrtle BeachPanama City

MYR - PTY

MYRPTY

Myrtle Beach Intl

Mon 12/15

4:03 pm-1:47 pm

2 stops21h 44m

Panama City Tocumen Intl

Thu 3/12

3:50 pm-5:10 pm

2 stops24h 20m

$440

Myrtle BeachPanama City

MYR - PTY

MYRPTY

Myrtle Beach Intl

Fri 11/21

6:15 am-12:40 am

2 stops18h 25m

Panama City Tocumen Intl

Thu 11/27

2:55 am-8:03 pm

2 stops17h 08m

$638

Myrtle BeachPanama City

MYR - PTY

MYRPTY

Myrtle Beach Intl

Fri 11/21

5:03 am-1:43 pm

2 stops8h 40m

Panama City Tocumen Intl

Fri 11/28

2:43 pm-11:08 am

2 stops20h 25m

$690

Myrtle BeachPanama City

MYR - PTY

MYRPTY

Myrtle Beach Intl

Fri 11/21

6:15 am-10:30 am

3 stops28h 15m

Panama City Tocumen Intl

Thu 11/27

2:55 am-11:54 pm

3 stops20h 59m

$698

Myrtle BeachPanama City

MYR - PTY

MYRPTY

Myrtle Beach Intl

Fri 11/21

6:15 am-10:30 am

3 stops28h 15m

Panama City Tocumen Intl

Fri 11/28

9:45 am-11:54 pm

2 stops14h 09m

$736

Myrtle BeachPanama City

MYR - PTY

MYRPTY

Myrtle Beach Intl

Fri 11/21

2:46 pm-1:00 am

2 stops34h 14m

Panama City Tocumen Intl

Fri 11/28

12:03 pm-11:54 pm

1 stop11h 51m

$773

Myrtle BeachPanama City

MYR - PTY

MYRPTY

Myrtle Beach Intl

Fri 11/21

2:46 pm-8:19 pm

1 stop29h 33m

Panama City Tocumen Intl

Thu 11/27

2:55 am-8:03 pm

2 stops17h 08m

$787

Myrtle BeachPanama City

MYR - PTY

MYRPTY

Myrtle Beach Intl

Mon 12/15

6:00 am-2:21 pm

1 stop8h 21m

Panama City Tocumen Intl

Thu 3/12

2:20 pm-11:35 pm

1 stop8h 15m

$798

Myrtle BeachPanama City

MYR - PTY

MYRPTY

Myrtle Beach Intl

Mon 12/15

6:00 am-2:21 pm

1 stop8h 21m

Panama City Tocumen Intl

Thu 3/12

2:20 pm-11:35 pm

1 stop8h 15m

$808

Myrtle BeachPanama City

MYR - PTY

MYRPTY

Myrtle Beach Intl

Fri 11/21

6:15 am-10:30 am

3 stops28h 15m

Panama City Tocumen Intl

Fri 11/28

2:55 pm-8:03 pm

3 stops29h 08m

$831

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

How to get the cheapest flight ticket from Myrtle Beach to Panama

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the cheapest day to depart on your flight to Panama?

According to our data, Wednesday is the cheapest day to fly to Panama from Myrtle Beach. The lowest ticket price found for a Wednesday departure recently was $475. Keep in mind that prices can always vary depending on your route and whether or not you are flying domestic or international. When flying out on a Thursday, the most expensive travel day of the week, you can expect to see flight prices from Myrtle Beach to Panama for around $587.

Cheap Myrtle Beach to Panama flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Myrtle Beach to Panama

Direct flights	None

There are no direct flights from Myrtle Beach to Panama. There are no popular flight routes from Myrtle Beach to Panama.

Search flight deals

When did momondo last update prices for flights from Myrtle Beach Intl Airport to Panama?
Prices for flights from Myrtle Beach Intl Airport to Panama refresh daily.
How many operators does momondo search for flights from Myrtle Beach Intl Airport to Panama?
The number of operators available for flights from Myrtle Beach Intl Airport to Panama is 1 as of October 2025.
How old do you have to be to fly from Myrtle Beach Intl Airport to Panama?
Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Myrtle Beach Intl Airport to Panama.
What documentation or ID do you need to fly to Panama?
The travel and health documents you'll need for your trip to Panama may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Panama. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

Best airlines flying from Myrtle Beach to Panama

Compare and see reviews for airlines that fly from Myrtle Beach to Panama with momondo

Airline	Rating	Free Cancellation	Price
American Airlines	PriceFrom $437	Free Cancellation	Rating 7.2 11,033 reviews		Search American Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Myrtle Beach to Panama?

Finding the right flight to Panama from Myrtle Beach is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Panama quick and easy, saving you time and money.

Can I find flights from Myrtle Beach to Panama with flexible booking policies on momondo?

Flights from Myrtle Beach to Panama with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Myrtle Beach to Panama?

Once all potential Myrtle Beach to Panama flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Myrtle Beach to Panama right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Panama from Myrtle Beach. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

An easier way to manage your Panama trip

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Popular cities in Panama

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Cheap flights from Myrtle Beach to Panama from $440

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Myrtle Beach to Panama departing on 12/15. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.

Big names and deals

Big names and deals

Filter for what you want

Filter for what you want

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Find the cheapest flights from Myrtle Beach to Panama

Cheap round-trip flights

Delta flights from Myrtle Beach to Panama

Our best Delta deals on Myrtle Beach to Panama flight tickets

American Airlines flights from Myrtle Beach to Panama

Our best American Airlines deals on Myrtle Beach to Panama flight tickets

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How to get the cheapest flight ticket from Myrtle Beach to Panama

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to Panama?

What airlines fly to Panama?

Cheap Myrtle Beach to Panama flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Myrtle Beach to Panama

Direct flights

When did momondo last update prices for flights from Myrtle Beach Intl Airport to Panama?

How many operators does momondo search for flights from Myrtle Beach Intl Airport to Panama?

How old do you have to be to fly from Myrtle Beach Intl Airport to Panama?

What documentation or ID do you need to fly to Panama?

Best airlines flying from Myrtle Beach to Panama

Compare and see reviews for airlines that fly from Myrtle Beach to Panama with momondo

Why use momondo?

Why should I use momondo to find a flight deal from Myrtle Beach to Panama?

Can I find flights from Myrtle Beach to Panama with flexible booking policies on momondo?

How can momondo help me find flights from Myrtle Beach to Panama?

I’m not ready to book a flight from Myrtle Beach to Panama right now. Can momondo alert me if prices change?

An easier way to manage your Panama trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

Find better results for your trip to Panama

Popular cities in Panama

Popular flights according to clicks in the last 7 days on momondo