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Cheap flights from Myrtle Beach to Panama from $244

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Myrtle Beach to Panama departing on 5/2. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Myrtle Beach to Panama

Cheap round-trip flights

Enter your travel dates to find the best prices.
United Airlines Logo
10:28 am - 2:14 pm
MYR
-
PTY
28h 46m
2 stops
United Airlines Logo
3:30 pm - 10:39 am
PTY
-
MYR
18h 09m
2 stops
$591United Airlines
Sat, Aug 22 - Sat, Aug 29
United Airlines Logo
11:30 am - 4:04 am
MYR
-
PTY
17h 34m
2 stops
United Airlines Logo
3:30 pm - 2:18 pm
PTY
-
MYR
21h 48m
2 stops
$601United Airlines
Sat, May 16 - Tue, May 19
American Airlines Logo
5:00 am - 12:46 pm
MYR
-
PTY
8h 46m
2 stops
American Airlines Logo
1:49 pm - 8:24 am
PTY
-
MYR
17h 35m
2 stops
$636American Airlines
Sun, May 3 - Sun, May 10
Multiple Airlines Logo
10:20 am - 5:00 pm
MYR
-
PTY
31h 40m
2 stops
Multiple Airlines Logo
12:15 pm - 8:36 pm
PTY
-
MYR
7h 21m
1 stop
$647Multiple Airlines
Sun, May 3 - Sun, May 10
United Airlines Logo
10:00 am - 7:31 pm
MYR
-
PTY
10h 31m
1 stop
United Airlines Logo
10:55 pm - 8:58 am
PTY
-
MYR
9h 03m
1 stop
$661United Airlines
Sat, Aug 22 - Sat, Aug 29
United Airlines Logo
6:00 pm - 4:04 am
MYR
-
PTY
11h 04m
1 stop
United Airlines Logo
3:30 pm - 2:18 pm
PTY
-
MYR
21h 48m
2 stops
$691United Airlines
Sat, May 16 - Tue, May 19
Multiple Airlines Logo
11:52 am - 8:19 pm
MYR
-
PTY
9h 27m
1 stop
Multiple Airlines Logo
12:15 pm - 8:36 pm
PTY
-
MYR
7h 21m
1 stop
$765Multiple Airlines
Sun, May 3 - Sun, May 10
American Airlines Logo
5:00 am - 12:46 pm
MYR
-
PTY
8h 46m
2 stops
American Airlines Logo
1:49 pm - 8:24 am
PTY
-
MYR
17h 35m
3 stops
$2,191American Airlines
Sun, May 3 - Sun, May 10
American Airlines Logo
7:00 am - 2:20 pm
MYR
-
PTY
8h 20m
2 stops
American Airlines Logo
3:20 pm - 8:56 am
PTY
-
MYR
16h 36m
3 stops
$2,318American Airlines
Sat, Aug 22 - Sat, Aug 29

United Airlines flights from Myrtle Beach to Panama

Our best United Airlines deals on Myrtle Beach to Panama flight tickets
United Airlines
Aug 22
MYR10:28 amMyrtle Beach Intl
28h 46m
2 stops
PTY2:14 pmPanama City Tocumen Intl
Aug 29
PTY3:30 pmPanama City Tocumen Intl
18h 09m
2 stops
MYR10:39 amMyrtle Beach Intl
$591
United Airlines
May 16
MYR11:30 amMyrtle Beach Intl
17h 34m
2 stops
PTY4:04 amPanama City Tocumen Intl
May 19
PTY3:30 pmPanama City Tocumen Intl
21h 48m
2 stops
MYR2:18 pmMyrtle Beach Intl
$601
United Airlines
Aug 22
MYR10:00 amMyrtle Beach Intl
10h 31m
1 stop
PTY7:31 pmPanama City Tocumen Intl
Aug 29
PTY10:55 pmPanama City Tocumen Intl
9h 03m
1 stop
MYR8:58 amMyrtle Beach Intl
$661

American Airlines flights from Myrtle Beach to Panama

Our best American Airlines deals on Myrtle Beach to Panama flight tickets
American Airlines
May 3
MYR5:00 amMyrtle Beach Intl
8h 46m
2 stops
PTY12:46 pmPanama City Tocumen Intl
May 10
PTY1:49 pmPanama City Tocumen Intl
17h 35m
2 stops
MYR8:24 amMyrtle Beach Intl
$636
American Airlines
May 3
MYR5:00 amMyrtle Beach Intl
8h 46m
2 stops
PTY12:46 pmPanama City Tocumen Intl
May 10
PTY1:49 pmPanama City Tocumen Intl
17h 35m
3 stops
MYR8:24 amMyrtle Beach Intl
$2,191
American Airlines
Aug 22
MYR7:00 amMyrtle Beach Intl
8h 20m
2 stops
PTY2:20 pmPanama City Tocumen Intl
Aug 29
PTY3:20 pmPanama City Tocumen Intl
16h 36m
3 stops
MYR8:56 amMyrtle Beach Intl
$2,318

momondo Fare Finder

 
Customize your flight search to find flights from Myrtle Beach to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated April 6, 2026.
Use the filters below to find and compare flights from Myrtle Beach to Panama that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Myrtle BeachPanama City

MYR - PTY

MYRPTY

Myrtle Beach Intl

Sat 8/22

10:28 am-2:14 pm

2 stops28h 46m

Panama City Tocumen Intl

Sat 8/29

3:30 pm-10:39 am

2 stops18h 09m

$591

Myrtle BeachPanama City

MYR - PTY

MYRPTY

Myrtle Beach Intl

Sat 5/16

11:30 am-4:04 am

2 stops17h 34m

Panama City Tocumen Intl

Tue 5/19

3:30 pm-2:18 pm

2 stops21h 48m

$601

Myrtle BeachPanama City

MYR - PTY

MYRPTY

Myrtle Beach Intl

Sun 5/3

5:00 am-12:46 pm

2 stops8h 46m

Panama City Tocumen Intl

Sun 5/10

1:49 pm-8:24 am

2 stops17h 35m

$636

Myrtle BeachPanama City

MYR - PTY

MYRPTY

Myrtle Beach Intl

Sun 5/3

10:20 am-5:00 pm

2 stops31h 40m

Panama City Tocumen Intl

Sun 5/10

12:15 pm-8:36 pm

1 stop7h 21m

$647

Myrtle BeachPanama City

MYR - PTY

MYRPTY

Myrtle Beach Intl

Sat 8/22

10:00 am-7:31 pm

1 stop10h 31m

Panama City Tocumen Intl

Sat 8/29

10:55 pm-8:58 am

1 stop9h 03m

$661

Myrtle BeachPanama City

MYR - PTY

MYRPTY

Myrtle Beach Intl

Sat 5/16

6:00 pm-4:04 am

1 stop11h 04m

Panama City Tocumen Intl

Tue 5/19

3:30 pm-2:18 pm

2 stops21h 48m

$691
Quickest round-trip

Myrtle BeachPanama City

MYR - PTY

MYRPTY

Myrtle Beach Intl

Sun 5/3

11:52 am-8:19 pm

1 stop9h 27m

Panama City Tocumen Intl

Sun 5/10

12:15 pm-8:36 pm

1 stop7h 21m

$765

Myrtle BeachPanama City

MYR - PTY

MYRPTY

Myrtle Beach Intl

Sun 5/3

5:00 am-12:46 pm

2 stops8h 46m

Panama City Tocumen Intl

Sun 5/10

1:49 pm-8:24 am

3 stops17h 35m

$2,191

Myrtle BeachPanama City

MYR - PTY

MYRPTY

Myrtle Beach Intl

Sat 8/22

7:00 am-2:20 pm

2 stops8h 20m

Panama City Tocumen Intl

Sat 8/29

3:20 pm-8:56 am

3 stops16h 36m

$2,318
Cheapest one-way

Myrtle BeachPanama City

MYR - PTY

MYRPTY

Myrtle Beach Intl

Sat 5/2

8:31 pm-2:15 pm

3 stops42h 44m

$244

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 16 resultsSorted by cheapest first
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See travel insights to Panama from

How to get the cheapest flight ticket from Myrtle Beach to Panama

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest airline that flies from Myrtle Beach Intl to Panama?

Delta is the most popular carrier operating from Myrtle Beach Intl to Panama

What airlines fly to Panama?

American Airlines, Delta and United Airlines are the top three most popular airlines that fly to Panama from Myrtle Beach according to our data. American Airlines is the first choice among our users, with 59% of people opting to fly with this airline when traveling to Panama. Keep in mind that there are 3 different airlines that fly to Panama on a routine basis, so you have a few additional options to choose from.

Cheap Myrtle Beach to Panama flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Myrtle Beach to Panama

Fastest flight time

18h 04m

Direct flights

None
The fastest flight from Myrtle Beach to Panama takes 18h 04m
There are no direct flights from Myrtle Beach to Panama. There are no popular flight routes from Myrtle Beach to Panama.
Search flight deals

Frequently asked questions about flying from Myrtle Beach to Panama

  • When did momondo last update prices for flights from Myrtle Beach Intl Airport to Panama?

    Prices for flights from Myrtle Beach Intl Airport to Panama refresh daily.

  • How old do you have to be to fly from Myrtle Beach Intl Airport to Panama?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Myrtle Beach Intl Airport to Panama.

  • What documentation or ID do you need to fly to Panama?

    The travel and health documents you'll need for your trip to Panama may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Panama. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

Why use momondo?

Why should I use momondo to find a flight deal from Myrtle Beach to Panama?

Finding the right flight to Panama from Myrtle Beach is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Panama quick and easy, saving you time and money.

Can I find flights from Myrtle Beach to Panama with flexible booking policies on momondo?

Flights from Myrtle Beach to Panama with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Myrtle Beach to Panama?

Once all potential Myrtle Beach to Panama flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Myrtle Beach to Panama right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Panama from Myrtle Beach. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

An easier way to manage your Panama trip

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