Cheap flights from Myrtle Beach to Panama from $306

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Myrtle Beach to Panama departing on 2/5. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
6:22 pm - 12:40 pm
MYR
-
PTY
19h 18m
2 stops
American Airlines Logo
1:40 pm - 8:32 am
PTY
-
MYR
17h 52m
2 stops
$481American Airlines
Thu, Mar 19 - Thu, Mar 26
American Airlines Logo
6:22 pm - 12:40 pm
MYR
-
PTY
19h 18m
2 stops
American Airlines Logo
1:40 pm - 11:21 am
PTY
-
MYR
20h 41m
2 stops
$521American Airlines
Mon, Mar 16 - Mon, Mar 23
American Airlines Logo
5:19 pm - 12:40 pm
MYR
-
PTY
20h 21m
2 stops
American Airlines Logo
1:40 pm - 12:14 pm
PTY
-
MYR
21h 34m
2 stops
$531American Airlines
Thu, Mar 19 - Thu, Mar 26
Multiple Airlines Logo
6:28 pm - 8:50 am
MYR
-
PTY
39h 22m
3 stops
Multiple Airlines Logo
2:55 pm - 5:33 pm
PTY
-
MYR
25h 38m
2 stops
$540Multiple Airlines
Sun, Mar 15 - Sun, Mar 22
Multiple Airlines Logo
6:28 pm - 1:00 am
MYR
-
PTY
31h 32m
2 stops
Multiple Airlines Logo
12:03 pm - 5:33 pm
PTY
-
MYR
28h 30m
1 stop
$546Multiple Airlines
Mon, Mar 16 - Mon, Mar 23
Multiple Airlines Logo
6:28 pm - 8:50 am
MYR
-
PTY
39h 22m
3 stops
Multiple Airlines Logo
9:45 am - 5:33 pm
PTY
-
MYR
30h 48m
3 stops
$571Multiple Airlines
Sun, Mar 15 - Sun, Mar 22
Multiple Airlines Logo
6:28 pm - 8:19 pm
MYR
-
PTY
26h 51m
1 stop
Multiple Airlines Logo
5:50 pm - 5:33 pm
PTY
-
MYR
22h 43m
2 stops
$572Multiple Airlines
Sun, Mar 15 - Sun, Mar 22
American Airlines Logo
5:44 pm - 1:27 pm
MYR
-
PTY
19h 43m
2 stops
American Airlines Logo
2:40 pm - 9:57 am
PTY
-
MYR
19h 17m
2 stops
$591American Airlines
Tue, Feb 10 - Tue, Mar 3
Multiple Airlines Logo
6:28 pm - 8:19 pm
MYR
-
PTY
26h 51m
1 stop
Multiple Airlines Logo
12:03 pm - 5:33 pm
PTY
-
MYR
28h 30m
1 stop
$607Multiple Airlines
Mon, Mar 16 - Mon, Mar 23
American Airlines Logo
6:22 pm - 2:20 pm
MYR
-
PTY
20h 58m
2 stops
American Airlines Logo
1:40 pm - 11:39 am
PTY
-
MYR
20h 59m
2 stops
$630American Airlines
Sun, Mar 15 - Sun, Mar 22

American Airlines flights from Myrtle Beach to Panama

Our best American Airlines deals on Myrtle Beach to Panama flight tickets
American Airlines
Mar 19
MYR6:22 pmMyrtle Beach Intl
19h 18m
2 stops
PTY12:40 pmPanama City Tocumen Intl
Mar 26
PTY1:40 pmPanama City Tocumen Intl
17h 52m
2 stops
MYR8:32 amMyrtle Beach Intl
$481
American Airlines
Mar 16
MYR6:22 pmMyrtle Beach Intl
19h 18m
2 stops
PTY12:40 pmPanama City Tocumen Intl
Mar 23
PTY1:40 pmPanama City Tocumen Intl
20h 41m
2 stops
MYR11:21 amMyrtle Beach Intl
$521
American Airlines
Mar 19
MYR5:19 pmMyrtle Beach Intl
20h 21m
2 stops
PTY12:40 pmPanama City Tocumen Intl
Mar 26
PTY1:40 pmPanama City Tocumen Intl
21h 34m
2 stops
MYR12:14 pmMyrtle Beach Intl
$531

Delta flights from Myrtle Beach to Panama

Our best Delta deals on Myrtle Beach to Panama flight tickets
Delta
Jul 22
MYR6:00 amMyrtle Beach Intl
8h 07m
1 stop
PTY1:07 pmPanama City Tocumen Intl
Jul 28
PTY2:20 pmPanama City Tocumen Intl
8h 19m
1 stop
MYR11:39 pmMyrtle Beach Intl
$655
Delta
Mar 19
MYR6:00 amMyrtle Beach Intl
8h 03m
1 stop
PTY1:03 pmPanama City Tocumen Intl
Mar 26
PTY2:28 pmPanama City Tocumen Intl
8h 36m
1 stop
MYR12:04 amMyrtle Beach Intl
$721
Delta
Mar 19
MYR6:00 amMyrtle Beach Intl
8h 03m
1 stop
PTY1:03 pmPanama City Tocumen Intl
Mar 26
PTY2:28 pmPanama City Tocumen Intl
8h 36m
1 stop
MYR12:04 amMyrtle Beach Intl
$797

momondo Fare Finder

 
Customize your flight search to find flights from Myrtle Beach to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated January 31, 2026.
Use the filters below to find and compare flights from Myrtle Beach to Panama that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Myrtle BeachPanama City

MYR - PTY

MYRPTY

Myrtle Beach Intl

Thu 3/19

6:22 pm-12:40 pm

2 stops19h 18m

Panama City Tocumen Intl

Thu 3/26

1:40 pm-8:32 am

2 stops17h 52m

$481

Myrtle BeachPanama City

MYR - PTY

MYRPTY

Myrtle Beach Intl

Mon 3/16

6:22 pm-12:40 pm

2 stops19h 18m

Panama City Tocumen Intl

Mon 3/23

1:40 pm-11:21 am

2 stops20h 41m

$521

Myrtle BeachPanama City

MYR - PTY

MYRPTY

Myrtle Beach Intl

Thu 3/19

5:19 pm-12:40 pm

2 stops20h 21m

Panama City Tocumen Intl

Thu 3/26

1:40 pm-12:14 pm

2 stops21h 34m

$531

Myrtle BeachPanama City

MYR - PTY

MYRPTY

Myrtle Beach Intl

Sun 3/15

6:28 pm-8:50 am

3 stops39h 22m

Panama City Tocumen Intl

Sun 3/22

2:55 pm-5:33 pm

2 stops25h 38m

$540

Myrtle BeachPanama City

MYR - PTY

MYRPTY

Myrtle Beach Intl

Mon 3/16

6:28 pm-1:00 am

2 stops31h 32m

Panama City Tocumen Intl

Mon 3/23

12:03 pm-5:33 pm

1 stop28h 30m

$546

Myrtle BeachPanama City

MYR - PTY

MYRPTY

Myrtle Beach Intl

Sun 3/15

6:28 pm-8:50 am

3 stops39h 22m

Panama City Tocumen Intl

Sun 3/22

9:45 am-5:33 pm

3 stops30h 48m

$571

Myrtle BeachPanama City

MYR - PTY

MYRPTY

Myrtle Beach Intl

Sun 3/15

6:28 pm-8:19 pm

1 stop26h 51m

Panama City Tocumen Intl

Sun 3/22

5:50 pm-5:33 pm

2 stops22h 43m

$572

Myrtle BeachPanama City

MYR - PTY

MYRPTY

Myrtle Beach Intl

Tue 2/10

5:44 pm-1:27 pm

2 stops19h 43m

Panama City Tocumen Intl

Tue 3/3

2:40 pm-9:57 am

2 stops19h 17m

$591

Myrtle BeachPanama City

MYR - PTY

MYRPTY

Myrtle Beach Intl

Mon 3/16

6:28 pm-8:19 pm

1 stop26h 51m

Panama City Tocumen Intl

Mon 3/23

12:03 pm-5:33 pm

1 stop28h 30m

$607

Myrtle BeachPanama City

MYR - PTY

MYRPTY

Myrtle Beach Intl

Sun 3/15

6:22 pm-2:20 pm

2 stops20h 58m

Panama City Tocumen Intl

Sun 3/22

1:40 pm-11:39 am

2 stops20h 59m

$630

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 13 resultsSorted by cheapest first
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See travel insights to Panama from

How to get the cheapest flight ticket from Myrtle Beach to Panama

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest airline that flies from Myrtle Beach Intl to Panama?

American Airlines and Delta are the most popular carriers operating from Myrtle Beach Intl to Panama

What airlines fly to Panama?

American Airlines, Delta and United Airlines are the top three most popular airlines that fly to Panama from Myrtle Beach according to our data. American Airlines is the first choice among our users, with 63% of people opting to fly with this airline when traveling to Panama. Keep in mind that there are 3 different airlines that fly to Panama on a routine basis, so you have a few additional options to choose from.

Cheap Myrtle Beach to Panama flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Myrtle Beach to Panama

Fastest flight time

7h 55m

Direct flights

None
The fastest flight from Myrtle Beach to Panama takes 7h 55m
There are no direct flights from Myrtle Beach to Panama. There are no popular flight routes from Myrtle Beach to Panama.
  • When did momondo last update prices for flights from Myrtle Beach Intl Airport to Panama?

    Prices for flights from Myrtle Beach Intl Airport to Panama refresh daily.

  • How old do you have to be to fly from Myrtle Beach Intl Airport to Panama?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Myrtle Beach Intl Airport to Panama.

  • What documentation or ID do you need to fly to Panama?

    The travel and health documents you'll need for your trip to Panama may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Panama. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

Why use momondo?

Why should I use momondo to find a flight deal from Myrtle Beach to Panama?

Finding the right flight to Panama from Myrtle Beach is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Panama quick and easy, saving you time and money.

Can I find flights from Myrtle Beach to Panama with flexible booking policies on momondo?

Flights from Myrtle Beach to Panama with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Myrtle Beach to Panama?

Once all potential Myrtle Beach to Panama flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Myrtle Beach to Panama right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Panama from Myrtle Beach. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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1 adult
Mon 3/2
Mon 3/9

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Popular cities in Panama

Popular flights according to clicks in the last 7 days on momondo