What airlines fly to Panama?

American Airlines, Delta and United Airlines are the top three most popular airlines that fly to Panama from Myrtle Beach according to our data. American Airlines is the first choice among our users, with 64% of people opting to fly with this airline when traveling to Panama. Keep in mind that there are 3 different airlines that fly to Panama on a routine basis, so you have a few additional options to choose from.

When did momondo last update prices for flights from Myrtle Beach Intl Airport to Panama?

Prices for flights from Myrtle Beach Intl Airport to Panama refresh daily.

How many operators does momondo search for flights from Myrtle Beach Intl Airport to Panama?

The number of operators available for flights from Myrtle Beach Intl Airport to Panama is 1 as of December 2025.

How old do you have to be to fly from Myrtle Beach Intl Airport to Panama?

Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Myrtle Beach Intl Airport to Panama.

What documentation or ID do you need to fly to Panama?

The travel and health documents you'll need for your trip to Panama may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Panama. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

$460 Cheap Flights from Myrtle Beach to Panama in 2025/26

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Round-trip

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6:26 pm - 12:15 pm

MYR

PTY

18h 49m2 stops

1:55 pm - 11:37 am

PTY

MYR

20h 42m2 stops

$460American Airlines

Wed, May 6 - Mon, May 11

6:35 pm - 2:22 pm

MYR

PTY

20h 47m2 stops

1:44 pm - 10:01 am

PTY

MYR

19h 17m2 stops

$480American Airlines

Thu, Mar 19 - Thu, Mar 26

6:00 am - 12:55 pm

MYR

PTY

7h 55m1 stop

2:20 pm - 11:38 pm

PTY

MYR

8h 18m1 stop

$578Delta

Wed, May 6 - Mon, May 11

6:17 pm - 12:25 pm

MYR

PTY

19h 08m2 stops

1:50 pm - 10:01 am

PTY

MYR

19h 11m2 stops

$670American Airlines

Sat, Jun 6 - Thu, Jun 11

6:00 am - 12:55 pm

MYR

PTY

7h 55m1 stop

2:20 pm - 11:59 pm

PTY

MYR

8h 39m1 stop

$868Delta

Thu, Mar 19 - Thu, Mar 26

6:00 am - 12:55 pm

MYR

PTY

7h 55m1 stop

2:20 pm - 11:38 pm

PTY

MYR

8h 18m1 stop

$967Delta

Sat, Jun 6 - Thu, Jun 11

5:28 am - 12:15 pm

MYR

PTY

7h 47m2 stops

1:55 pm - 8:14 am

PTY

MYR

17h 19m3 stops

$2,255American Airlines

Wed, May 6 - Mon, May 11

11:25 am - 7:31 pm

MYR

PTY

9h 06m1 stop

10:29 pm - 4:49 pm

PTY

MYR

17h 20m2 stops

$3,950United Airlines

Wed, May 6 - Wed, May 6

American Airlines flights from Myrtle Beach to Panama

Our best American Airlines deals on Myrtle Beach to Panama flight tickets

American Airlines

May 6

MYR6:26 pmMyrtle Beach Intl

18h 49m

2 stops

PTY12:15 pmPanama City Tocumen Intl

May 11

PTY1:55 pmPanama City Tocumen Intl

20h 42m

2 stops

MYR11:37 amMyrtle Beach Intl

$460

Find similar

American Airlines

Mar 19

MYR6:35 pmMyrtle Beach Intl

20h 47m

2 stops

PTY2:22 pmPanama City Tocumen Intl

Mar 26

PTY1:44 pmPanama City Tocumen Intl

19h 17m

2 stops

MYR10:01 amMyrtle Beach Intl

$480

Find similar

American Airlines

Jan 6

MYR5:44 pmMyrtle Beach Intl

21h 47m

2 stops

PTY3:31 pmPanama City Tocumen Intl

Jan 12

PTY2:27 pmPanama City Tocumen Intl

19h 51m

2 stops

MYR10:18 amMyrtle Beach Intl

$540

Find similar

Delta flights from Myrtle Beach to Panama

Our best Delta deals on Myrtle Beach to Panama flight tickets

Delta

May 6

MYR6:00 amMyrtle Beach Intl

7h 55m

1 stop

PTY12:55 pmPanama City Tocumen Intl

May 11

PTY2:20 pmPanama City Tocumen Intl

8h 18m

1 stop

MYR11:38 pmMyrtle Beach Intl

$578

Find similar

Delta

Mar 19

MYR6:00 amMyrtle Beach Intl

7h 55m

1 stop

PTY12:55 pmPanama City Tocumen Intl

Mar 26

PTY2:20 pmPanama City Tocumen Intl

8h 39m

1 stop

MYR11:59 pmMyrtle Beach Intl

$868

Find similar

Delta

Dec 24

MYR6:00 amMyrtle Beach Intl

14h 00m

1 stop

PTY8:00 pmPanama City Tocumen Intl

Dec 30

PTY8:00 amPanama City Tocumen Intl

14h 50m

1 stop

MYR10:50 pmMyrtle Beach Intl

$870

Find similar

Fly from

Fly to

Route

Depart

Return

Price

Myrtle BeachPanama City

MYR - PTY

MYRPTY

Myrtle Beach Intl

Wed 5/6

6:26 pm-12:15 pm

2 stops18h 49m

Panama City Tocumen Intl

Mon 5/11

1:55 pm-11:37 am

2 stops20h 42m

$460

Myrtle BeachPanama City

MYR - PTY

MYRPTY

Myrtle Beach Intl

Thu 3/19

6:35 pm-2:22 pm

2 stops20h 47m

Panama City Tocumen Intl

Thu 3/26

1:44 pm-10:01 am

2 stops19h 17m

$480

Myrtle BeachPanama City

MYR - PTY

MYRPTY

Myrtle Beach Intl

Wed 5/6

6:00 am-12:55 pm

1 stop7h 55m

Panama City Tocumen Intl

Mon 5/11

2:20 pm-11:38 pm

1 stop8h 18m

$578

Myrtle BeachPanama City

MYR - PTY

MYRPTY

Myrtle Beach Intl

Sat 6/6

6:17 pm-12:25 pm

2 stops19h 08m

Panama City Tocumen Intl

Thu 6/11

1:50 pm-10:01 am

2 stops19h 11m

$670

Myrtle BeachPanama City

MYR - PTY

MYRPTY

Myrtle Beach Intl

Thu 3/19

6:00 am-12:55 pm

1 stop7h 55m

Panama City Tocumen Intl

Thu 3/26

2:20 pm-11:59 pm

1 stop8h 39m

$868

Myrtle BeachPanama City

MYR - PTY

MYRPTY

Myrtle Beach Intl

Sat 6/6

6:00 am-12:55 pm

1 stop7h 55m

Panama City Tocumen Intl

Thu 6/11

2:20 pm-11:38 pm

1 stop8h 18m

$967

Myrtle BeachPanama City

MYR - PTY

MYRPTY

Myrtle Beach Intl

Wed 5/6

5:28 am-12:15 pm

2 stops7h 47m

Panama City Tocumen Intl

Mon 5/11

1:55 pm-8:14 am

3 stops17h 19m

$2,255

Myrtle BeachPanama City

MYR - PTY

MYRPTY

Myrtle Beach Intl

Wed 5/6

11:25 am-7:31 pm

1 stop9h 06m

Panama City Tocumen Intl

Wed 5/6

10:29 pm-4:49 pm

2 stops17h 20m

$3,950

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

How to get the cheapest flight ticket from Myrtle Beach to Panama

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the cheapest day to depart on your flight to Panama?

According to our data, Wednesday is the cheapest day to fly to Panama from Myrtle Beach. The lowest ticket price found for a Wednesday departure recently was $475. Keep in mind that prices can always vary depending on your route and whether or not you are flying domestic or international. When flying out on a Thursday, the most expensive travel day of the week, you can expect to see flight prices from Myrtle Beach to Panama for around $587.

Cheap Myrtle Beach to Panama flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Myrtle Beach to Panama

Fastest flight time	7h 55m
Direct flights	None

The fastest flight from Myrtle Beach to Panama takes 7h 55m

There are no direct flights from Myrtle Beach to Panama. There are no popular flight routes from Myrtle Beach to Panama.

Search flight deals

When did momondo last update prices for flights from Myrtle Beach Intl Airport to Panama?
Prices for flights from Myrtle Beach Intl Airport to Panama refresh daily.
How many operators does momondo search for flights from Myrtle Beach Intl Airport to Panama?
The number of operators available for flights from Myrtle Beach Intl Airport to Panama is 1 as of December 2025.
How old do you have to be to fly from Myrtle Beach Intl Airport to Panama?
Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Myrtle Beach Intl Airport to Panama.
What documentation or ID do you need to fly to Panama?
The travel and health documents you'll need for your trip to Panama may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Panama. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

Best airlines flying from Myrtle Beach to Panama

Compare and see reviews for airlines that fly from Myrtle Beach to Panama with momondo

Airline	Rating	Free Cancellation	Price
American Airlines	PriceFrom $437	Free Cancellation	Rating 7.2 11,048 reviews		Search American Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Myrtle Beach to Panama?

Finding the right flight to Panama from Myrtle Beach is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Panama quick and easy, saving you time and money.

Can I find flights from Myrtle Beach to Panama with flexible booking policies on momondo?

Flights from Myrtle Beach to Panama with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Myrtle Beach to Panama?

Once all potential Myrtle Beach to Panama flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Myrtle Beach to Panama right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Panama from Myrtle Beach. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

An easier way to manage your Panama trip

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Popular cities in Panama

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Cheap flights from Myrtle Beach to Panama from $460

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Myrtle Beach to Panama departing on 5/6. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.

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Big names and deals

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Filter for what you want

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Find the cheapest flights from Myrtle Beach to Panama

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American Airlines flights from Myrtle Beach to Panama

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Delta flights from Myrtle Beach to Panama

Our best Delta deals on Myrtle Beach to Panama flight tickets

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How to get the cheapest flight ticket from Myrtle Beach to Panama

What is the cheapest day to depart on your flight to Panama?

What airlines fly to Panama?

Cheap Myrtle Beach to Panama flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Myrtle Beach to Panama

Fastest flight time

Direct flights

When did momondo last update prices for flights from Myrtle Beach Intl Airport to Panama?

How many operators does momondo search for flights from Myrtle Beach Intl Airport to Panama?

How old do you have to be to fly from Myrtle Beach Intl Airport to Panama?

What documentation or ID do you need to fly to Panama?

Best airlines flying from Myrtle Beach to Panama

Compare and see reviews for airlines that fly from Myrtle Beach to Panama with momondo

Why use momondo?

Why should I use momondo to find a flight deal from Myrtle Beach to Panama?

Can I find flights from Myrtle Beach to Panama with flexible booking policies on momondo?

How can momondo help me find flights from Myrtle Beach to Panama?

I’m not ready to book a flight from Myrtle Beach to Panama right now. Can momondo alert me if prices change?

An easier way to manage your Panama trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

Find better results for your trip to Panama

Popular cities in Panama

Popular flights according to clicks in the last 7 days on momondo