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Cheap flights from Myrtle Beach to Panama from $291

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Myrtle Beach to Panama departing on 8/18. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Find the cheapest flights from Myrtle Beach to Panama

Cheap round-trip flights

Enter your travel dates to find the best prices.
Delta Logo
6:00 am - 12:58 pm
MYR
-
PTY
7h 58m
1 stop
Delta Logo
2:23 pm - 11:28 pm
PTY
-
MYR
8h 05m
1 stop
$637Delta
Sat, Sep 12 - Wed, Sep 16
American Airlines Logo
4:23 pm - 12:16 pm
MYR
-
PTY
20h 53m
2 stops
American Airlines Logo
1:16 pm - 11:37 am
PTY
-
MYR
21h 21m
2 stops
$641American Airlines
Sat, Sep 12 - Wed, Sep 16
Delta Logo
6:00 am - 12:55 pm
MYR
-
PTY
7h 55m
1 stop
Delta Logo
2:20 pm - 11:30 pm
PTY
-
MYR
8h 10m
1 stop
$677Delta
Fri, Aug 14 - Thu, Aug 20
American Airlines Logo
6:04 pm - 12:39 pm
MYR
-
PTY
19h 35m
2 stops
American Airlines Logo
1:39 pm - 11:34 am
PTY
-
MYR
20h 55m
2 stops
$681American Airlines
Fri, Aug 14 - Thu, Aug 20
American Airlines Logo
5:15 pm - 12:39 pm
MYR
-
PTY
20h 24m
2 stops
American Airlines Logo
1:39 pm - 11:34 am
PTY
-
MYR
20h 55m
2 stops
$686American Airlines
Thu, Aug 20 - Sun, Aug 23
Delta Logo
6:00 am - 1:56 pm
MYR
-
PTY
7h 56m
1 stop
Delta Logo
2:25 pm - 11:35 pm
PTY
-
MYR
8h 10m
1 stop
$687Delta
Sun, Nov 1 - Fri, Apr 30
United Airlines Logo
3:15 pm - 2:14 pm
MYR
-
PTY
23h 59m
2 stops
United Airlines Logo
3:30 pm - 2:19 pm
PTY
-
MYR
21h 49m
2 stops
$691United Airlines
Mon, Aug 3 - Thu, Aug 6
United Airlines Logo
7:49 pm - 4:04 am
MYR
-
PTY
9h 15m
1 stop
United Airlines Logo
3:30 pm - 2:53 pm
PTY
-
MYR
22h 23m
2 stops
$741United Airlines
Thu, Aug 20 - Sun, Aug 23
United Airlines Logo
10:23 am - 4:04 am
MYR
-
PTY
18h 41m
2 stops
United Airlines Logo
3:30 pm - 2:17 pm
PTY
-
MYR
21h 47m
2 stops
$756United Airlines
Thu, Sep 3 - Thu, Sep 10
Delta Logo
6:00 am - 12:55 pm
MYR
-
PTY
7h 55m
1 stop
Delta Logo
2:20 pm - 11:30 pm
PTY
-
MYR
8h 10m
1 stop
$780Delta
Thu, Aug 20 - Sun, Aug 23

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American Airlines flights from Myrtle Beach to Panama

Our best American Airlines deals on Myrtle Beach to Panama flight tickets
American Airlines
Sep 12
MYR4:23 pmMyrtle Beach Intl
20h 53m
2 stops
PTY12:16 pmPanama City Tocumen Intl
Sep 16
PTY1:16 pmPanama City Tocumen Intl
21h 21m
2 stops
MYR11:37 amMyrtle Beach Intl
$641
American Airlines
Aug 14
MYR6:04 pmMyrtle Beach Intl
19h 35m
2 stops
PTY12:39 pmPanama City Tocumen Intl
Aug 20
PTY1:39 pmPanama City Tocumen Intl
20h 55m
2 stops
MYR11:34 amMyrtle Beach Intl
$681
American Airlines
Aug 20
MYR5:15 pmMyrtle Beach Intl
20h 24m
2 stops
PTY12:39 pmPanama City Tocumen Intl
Aug 23
PTY1:39 pmPanama City Tocumen Intl
20h 55m
2 stops
MYR11:34 amMyrtle Beach Intl
$686

Delta flights from Myrtle Beach to Panama

Our best Delta deals on Myrtle Beach to Panama flight tickets
Delta
Sep 12
MYR6:00 amMyrtle Beach Intl
7h 58m
1 stop
PTY12:58 pmPanama City Tocumen Intl
Sep 16
PTY2:23 pmPanama City Tocumen Intl
8h 05m
1 stop
MYR11:28 pmMyrtle Beach Intl
$637
Delta
Aug 14
MYR6:00 amMyrtle Beach Intl
7h 55m
1 stop
PTY12:55 pmPanama City Tocumen Intl
Aug 20
PTY2:20 pmPanama City Tocumen Intl
8h 10m
1 stop
MYR11:30 pmMyrtle Beach Intl
$677
Delta
Nov 1
MYR6:00 amMyrtle Beach Intl
7h 56m
1 stop
PTY1:56 pmPanama City Tocumen Intl
Apr 30
PTY2:25 pmPanama City Tocumen Intl
8h 10m
1 stop
MYR11:35 pmMyrtle Beach Intl
$687

momondo Fare Finder

 
Customize your flight search to find flights from Myrtle Beach to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated July 21, 2026.
Use the filters below to find and compare flights from Myrtle Beach to Panama that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

Myrtle BeachPanama City

MYR - PTY

MYRPTY

Myrtle Beach Intl

Sat 9/12

6:00 am-12:58 pm

1 stop7h 58m

Panama City Tocumen Intl

Wed 9/16

2:23 pm-11:28 pm

1 stop8h 05m

$637

Myrtle BeachPanama City

MYR - PTY

MYRPTY

Myrtle Beach Intl

Sat 9/12

4:23 pm-12:16 pm

2 stops20h 53m

Panama City Tocumen Intl

Wed 9/16

1:16 pm-11:37 am

2 stops21h 21m

$641

Myrtle BeachPanama City

MYR - PTY

MYRPTY

Myrtle Beach Intl

Fri 8/14

6:00 am-12:55 pm

1 stop7h 55m

Panama City Tocumen Intl

Thu 8/20

2:20 pm-11:30 pm

1 stop8h 10m

$677

Myrtle BeachPanama City

MYR - PTY

MYRPTY

Myrtle Beach Intl

Fri 8/14

6:04 pm-12:39 pm

2 stops19h 35m

Panama City Tocumen Intl

Thu 8/20

1:39 pm-11:34 am

2 stops20h 55m

$681

Myrtle BeachPanama City

MYR - PTY

MYRPTY

Myrtle Beach Intl

Thu 8/20

5:15 pm-12:39 pm

2 stops20h 24m

Panama City Tocumen Intl

Sun 8/23

1:39 pm-11:34 am

2 stops20h 55m

$686

Myrtle BeachPanama City

MYR - PTY

MYRPTY

Myrtle Beach Intl

Sun 11/1

6:00 am-1:56 pm

1 stop7h 56m

Panama City Tocumen Intl

Fri 4/30

2:25 pm-11:35 pm

1 stop8h 10m

$687

Myrtle BeachPanama City

MYR - PTY

MYRPTY

Myrtle Beach Intl

Mon 8/3

3:15 pm-2:14 pm

2 stops23h 59m

Panama City Tocumen Intl

Thu 8/6

3:30 pm-2:19 pm

2 stops21h 49m

$691

Myrtle BeachPanama City

MYR - PTY

MYRPTY

Myrtle Beach Intl

Thu 8/20

7:49 pm-4:04 am

1 stop9h 15m

Panama City Tocumen Intl

Sun 8/23

3:30 pm-2:53 pm

2 stops22h 23m

$741

Myrtle BeachPanama City

MYR - PTY

MYRPTY

Myrtle Beach Intl

Thu 9/3

10:23 am-4:04 am

2 stops18h 41m

Panama City Tocumen Intl

Thu 9/10

3:30 pm-2:17 pm

2 stops21h 47m

$756

Myrtle BeachPanama City

MYR - PTY

MYRPTY

Myrtle Beach Intl

Thu 8/20

6:00 am-12:55 pm

1 stop7h 55m

Panama City Tocumen Intl

Sun 8/23

2:20 pm-11:30 pm

1 stop8h 10m

$780

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 17 resultsSorted by cheapest first
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See travel insights to Panama from

How to get the cheapest flight ticket from Myrtle Beach to Panama

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest airline that flies from Myrtle Beach Intl to Panama?

American Airlines and Delta are the most popular carriers operating from Myrtle Beach Intl to Panama

What airlines fly to Panama?

American Airlines, Delta and United Airlines are the top three most popular airlines that fly to Panama from Myrtle Beach according to our data. American Airlines is the first choice among our users, with 55% of people opting to fly with this airline when traveling to Panama. Keep in mind that there are 3 different airlines that fly to Panama on a routine basis, so you have a few additional options to choose from.

Cheap Myrtle Beach to Panama flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Myrtle Beach to Panama

Fastest flight time

7h 58m

Direct flights

None
The fastest flight from Myrtle Beach to Panama takes 7h 58m
There are no direct flights from Myrtle Beach to Panama. There are no popular flight routes from Myrtle Beach to Panama.
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Frequently asked questions about flying from Myrtle Beach to Panama

  • When did momondo last update prices for flights from Myrtle Beach Intl Airport to Panama?

    Prices for flights from Myrtle Beach Intl Airport to Panama refresh daily.

  • How old do you have to be to fly from Myrtle Beach Intl Airport to Panama?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Myrtle Beach Intl Airport to Panama.

  • What documentation or ID do you need to fly to Panama?

    The travel and health documents you'll need for your trip to Panama may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Panama. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

Why use momondo?

Why should I use momondo to find a flight deal from Myrtle Beach to Panama?

Finding the right flight to Panama from Myrtle Beach is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Panama quick and easy, saving you time and money.

Can I find flights from Myrtle Beach to Panama with flexible booking policies on momondo?

Flights from Myrtle Beach to Panama with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Myrtle Beach to Panama?

Once all potential Myrtle Beach to Panama flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Myrtle Beach to Panama right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Panama from Myrtle Beach. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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