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Cheap flights from Missouri to Grand Cayman from $366

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Missouri to Grand Cayman departing on 4/18. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Missouri to Grand Cayman

Cheap round-trip flights

Enter your travel dates to find the best prices.
Air Canada Logo
4:05 pm - 11:10 am
STL
-
GCM
19h 05m1 stop
Air Canada Logo
12:25 pm - 12:06 pm
GCM
-
STL
23h 41m1 stop
$366Air Canada
Sat, Apr 18 - Sat, May 2
Air Canada Logo
4:05 pm - 11:10 am
STL
-
GCM
19h 05m1 stop
Air Canada Logo
12:25 pm - 8:05 pm
GCM
-
STL
31h 40m2 stops
$369Air Canada
Sat, Apr 18 - Sat, May 2
Air Canada Logo
4:05 pm - 11:10 am
STL
-
GCM
19h 05m1 stop
Air Canada Logo
12:25 pm - 12:06 pm
GCM
-
STL
23h 41m1 stop
$376Air Canada
Sat, Apr 18 - Sat, May 2
Air Canada Logo
4:05 pm - 11:10 am
STL
-
GCM
19h 05m1 stop
Air Canada Logo
12:25 pm - 12:06 pm
GCM
-
STL
23h 41m1 stop
$377Air Canada
Sat, Apr 18 - Sat, May 2
Air Canada Logo
4:05 pm - 11:10 am
STL
-
GCM
19h 05m1 stop
Air Canada Logo
12:25 pm - 8:05 pm
GCM
-
STL
31h 40m2 stops
$380Air Canada
Sat, Apr 18 - Sat, May 2
American Airlines Logo
7:00 am - 8:20 pm
STL
-
GCM
12h 20m2 stops
American Airlines Logo
8:50 am - 10:05 pm
GCM
-
STL
14h 15m1 stop
$388American Airlines
Thu, Feb 5 - Thu, Feb 12
Delta Logo
6:00 am - 12:40 pm
STL
-
GCM
5h 40m1 stop
Delta Logo
2:05 pm - 11:36 pm
GCM
-
STL
10h 31m1 stop
$390Delta
Mon, Feb 2 - Sat, Feb 7
United Airlines Logo
6:30 am - 1:45 pm
STL
-
GCM
6h 15m1 stop
United Airlines Logo
5:30 pm - 12:29 pm
GCM
-
STL
19h 59m2 stops
$395United Airlines
Mon, Feb 2 - Sat, Feb 7
Delta Logo
5:50 am - 12:40 pm
MCI
-
GCM
5h 50m1 stop
Delta Logo
3:55 pm - 11:27 pm
GCM
-
MCI
8h 32m1 stop
$406Delta
Sat, Jan 31 - Sat, Feb 7
American Airlines Logo
10:58 am - 8:20 pm
MCI
-
GCM
8h 22m2 stops
American Airlines Logo
12:50 pm - 11:59 pm
GCM
-
MCI
12h 09m1 stop
$411American Airlines
Sat, Jan 31 - Sat, Feb 7

Air Canada flights from Missouri to Grand Cayman

Our best Air Canada deals on Missouri to Grand Cayman flight tickets
Air Canada
Apr 18
STL4:05 pmLambert-St Louis
19h 05m
1 stop
GCM11:10 amGeorge Town Owen Roberts Intl
May 2
GCM12:25 pmGeorge Town Owen Roberts Intl
23h 41m
1 stop
STL12:06 pmLambert-St Louis
$366
Find similar
Air Canada
Apr 18
STL4:05 pmLambert-St Louis
19h 05m
1 stop
GCM11:10 amGeorge Town Owen Roberts Intl
May 2
GCM12:25 pmGeorge Town Owen Roberts Intl
31h 40m
2 stops
STL8:05 pmLambert-St Louis
$369
Find similar
Air Canada
Apr 18
STL4:05 pmLambert-St Louis
19h 05m
1 stop
GCM11:10 amGeorge Town Owen Roberts Intl
May 2
GCM12:25 pmGeorge Town Owen Roberts Intl
23h 41m
1 stop
STL12:06 pmLambert-St Louis
$376
Find similar

American Airlines flights from Missouri to Grand Cayman

Our best American Airlines deals on Missouri to Grand Cayman flight tickets
American Airlines
Feb 5
STL7:00 amLambert-St Louis
12h 20m
2 stops
GCM8:20 pmGeorge Town Owen Roberts Intl
Feb 12
GCM8:50 amGeorge Town Owen Roberts Intl
14h 15m
1 stop
STL10:05 pmLambert-St Louis
$388
Find similar
American Airlines
Apr 18
STL7:03 pmLambert-St Louis
17h 42m
2 stops
GCM12:45 pmGeorge Town Owen Roberts Intl
May 2
GCM3:20 pmGeorge Town Owen Roberts Intl
17h 35m
1 stop
STL8:55 amLambert-St Louis
$400
Find similar
American Airlines
Jan 31
MCI10:58 amKansas City
8h 22m
2 stops
GCM8:20 pmGeorge Town Owen Roberts Intl
Feb 7
GCM12:50 pmGeorge Town Owen Roberts Intl
12h 09m
1 stop
MCI11:59 pmKansas City
$411
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Missouri to Grand Cayman that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated December 24, 2025.
Use the filters below to find and compare flights from Missouri to Grand Cayman that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

St. LouisGeorge Town

STL - GCM

STLGCM

Lambert-St Louis

Sat 4/18

4:05 pm-11:10 am

1 stop19h 05m

George Town Owen Roberts Intl

Sat 5/2

12:25 pm-12:06 pm

1 stop23h 41m

$366

St. LouisGeorge Town

STL - GCM

STLGCM

Lambert-St Louis

Sat 4/18

4:05 pm-11:10 am

1 stop19h 05m

George Town Owen Roberts Intl

Sat 5/2

12:25 pm-8:05 pm

2 stops31h 40m

$369

St. LouisGeorge Town

STL - GCM

STLGCM

Lambert-St Louis

Sat 4/18

4:05 pm-11:10 am

1 stop19h 05m

George Town Owen Roberts Intl

Sat 5/2

12:25 pm-12:06 pm

1 stop23h 41m

$376

St. LouisGeorge Town

STL - GCM

STLGCM

Lambert-St Louis

Sat 4/18

4:05 pm-11:10 am

1 stop19h 05m

George Town Owen Roberts Intl

Sat 5/2

12:25 pm-12:06 pm

1 stop23h 41m

$377

St. LouisGeorge Town

STL - GCM

STLGCM

Lambert-St Louis

Sat 4/18

4:05 pm-11:10 am

1 stop19h 05m

George Town Owen Roberts Intl

Sat 5/2

12:25 pm-8:05 pm

2 stops31h 40m

$380

St. LouisGeorge Town

STL - GCM

STLGCM

Lambert-St Louis

Thu 2/5

7:00 am-8:20 pm

2 stops12h 20m

George Town Owen Roberts Intl

Thu 2/12

8:50 am-10:05 pm

1 stop14h 15m

$388

St. LouisGeorge Town

STL - GCM

STLGCM

Lambert-St Louis

Mon 2/2

6:00 am-12:40 pm

1 stop5h 40m

George Town Owen Roberts Intl

Sat 2/7

2:05 pm-11:36 pm

1 stop10h 31m

$390

St. LouisGeorge Town

STL - GCM

STLGCM

Lambert-St Louis

Mon 2/2

6:30 am-1:45 pm

1 stop6h 15m

George Town Owen Roberts Intl

Sat 2/7

5:30 pm-12:29 pm

2 stops19h 59m

$395

Kansas CityGeorge Town

MCI - GCM

MCIGCM

Kansas City

Sat 1/31

5:50 am-12:40 pm

1 stop5h 50m

George Town Owen Roberts Intl

Sat 2/7

3:55 pm-11:27 pm

1 stop8h 32m

$406

Kansas CityGeorge Town

MCI - GCM

MCIGCM

Kansas City

Sat 1/31

10:58 am-8:20 pm

2 stops8h 22m

George Town Owen Roberts Intl

Sat 2/7

12:50 pm-11:59 pm

1 stop12h 09m

$411

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

See travel insights to Grand Cayman from

How to get the cheapest flight ticket from Missouri to Grand Cayman

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Grand Cayman?

The cheapest month to fly to Grand Cayman from Missouri is in September. Flight prices, which tend to average around $468, are often lower during this time because this is during the off-season. If you don’t want to visit Grand Cayman in September, then you should wait until January to fly from Missouri, when ticket prices are also cheap, with an average price of $536.

What is the cheapest day to depart on your flight to Grand Cayman?

The cheapest day to depart from Missouri to Grand Cayman is on a Wednesday when prices can be found for as low as $492. On the other hand, Saturday is the most expensive day to depart from Missouri because it is more convenient for both business and leisure travelers. As a result, prices tend to be around $665.

How far in advance should I book a flight to Grand Cayman?

You are more likely to see cheaper flights to Grand Cayman from Missouri when booking weeks ahead of your departure date. In general, you can expect to find flights to Grand Cayman for around $611 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Grand Cayman from Missouri for as low as $510 on momondo.

Can stopping save me money on Missouri to Grand Cayman flights?

No. A direct flight is the cheapest option for a flight between Missouri to Grand Cayman.

Cheap Missouri to Grand Cayman flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Missouri to Grand Cayman

Fastest flight time

5h 24m

Direct flights

None
The fastest flight from Missouri to Grand Cayman takes 5h 24m
There are no direct flights from Missouri to Grand Cayman. There are no popular flight routes from Missouri to Grand Cayman.
Search flight deals

  • When did momondo last update prices for flights from Missouri to Grand Cayman?

    Prices for flights from Missouri to Grand Cayman refresh daily.

  • How many operators does momondo search for flights from Missouri to Grand Cayman?

  • How old do you have to be to fly from Missouri to Grand Cayman?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Missouri to Grand Cayman.

  • What documentation or ID do you need to fly to Grand Cayman?

    The required travel and health documents for your Grand Cayman trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Grand Cayman. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular plane model from Missouri to Grand Cayman?

Best airlines flying from Missouri to Grand Cayman

Compare and see reviews for airlines that fly from Missouri to Grand Cayman with momondo
Airline
Rating
Free Cancellation
Price
United AirlinesPriceFrom $238Free CancellationRating
7.4
9,116 reviews
Search United Airlines flights
DeltaPriceFrom $266Free CancellationRating
7.9
8,011 reviews
Search Delta flights
SouthwestPriceFrom $429Free CancellationRating
8.0
4,257 reviews
Search Southwest flights
American AirlinesPriceFrom $439Free CancellationRating
7.2
11,056 reviews
Search American Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Missouri to Grand Cayman?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Grand Cayman from Missouri.

Can I find flights from Missouri to Grand Cayman with flexible booking policies on momondo?

Flights from Missouri to Grand Cayman with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Missouri to Grand Cayman?

momondo helps you find the best flight between Missouri and Grand Cayman by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Missouri to Grand Cayman right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Grand Cayman from Missouri. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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