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Cheap flights from Chicago Midway Airport to Panama from $263

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Chicago Midway Airport to Panama departing on 8/4. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Chicago Midway Airport to Panama

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
6:00 am - 8:34 pm
MDW
-
PTY
14h 34m
1 stop
Multiple Airlines Logo
10:26 am - 6:37 pm
PTY
-
MDW
8h 11m
1 stop
$556Multiple Airlines
Sat, Apr 18 - Sat, Apr 25
Multiple Airlines Logo
6:30 am - 1:55 am
MDW
-
PTY
19h 25m
3 stops
Multiple Airlines Logo
10:26 am - 7:31 pm
PTY
-
MDW
9h 05m
1 stop
$573Multiple Airlines
Sat, Apr 11 - Tue, Apr 21
Multiple Airlines Logo
6:00 am - 8:34 pm
MDW
-
PTY
14h 34m
1 stop
Multiple Airlines Logo
9:33 pm - 7:31 pm
PTY
-
MDW
21h 58m
2 stops
$574Multiple Airlines
Tue, May 5 - Tue, May 12
Multiple Airlines Logo
6:30 am - 2:30 pm
MDW
-
PTY
8h 00m
1 stop
Multiple Airlines Logo
10:25 am - 10:14 pm
PTY
-
MDW
11h 49m
2 stops
$581Multiple Airlines
Mon, Apr 13 - Sat, May 2
Multiple Airlines Logo
6:00 am - 8:34 pm
MDW
-
PTY
14h 34m
1 stop
Multiple Airlines Logo
9:33 pm - 7:31 pm
PTY
-
MDW
21h 58m
2 stops
$591Multiple Airlines
Thu, Apr 16 - Mon, Apr 20
Multiple Airlines Logo
6:30 am - 7:20 pm
MDW
-
PTY
12h 50m
1 stop
Multiple Airlines Logo
10:10 am - 8:04 am
PTY
-
MDW
21h 54m
2 stops
$601Multiple Airlines
Sat, Apr 11 - Wed, Apr 15
Multiple Airlines Logo
7:34 pm - 8:34 pm
MDW
-
PTY
25h 00m
1 stop
Multiple Airlines Logo
10:25 am - 10:14 pm
PTY
-
MDW
11h 49m
2 stops
$605Multiple Airlines
Sat, Apr 18 - Sat, Apr 25
Delta Logo
6:00 am - 1:02 pm
MDW
-
PTY
7h 02m
1 stop
Delta Logo
2:27 pm - 10:28 pm
PTY
-
MDW
8h 01m
1 stop
$610Delta
Sun, Apr 19 - Sat, Apr 25
Multiple Airlines Logo
2:15 pm - 8:06 am
MDW
-
PTY
17h 51m
2 stops
Multiple Airlines Logo
10:26 am - 10:19 pm
PTY
-
MDW
11h 53m
1 stop
$612Multiple Airlines
Wed, Apr 22 - Mon, Apr 27
Delta Logo
5:40 am - 1:02 pm
MDW
-
PTY
7h 22m
1 stop
Delta Logo
2:27 pm - 10:28 pm
PTY
-
MDW
8h 01m
1 stop
$630Delta
Sat, May 2 - Wed, May 6

LATAM Airlines flights from Chicago Midway Airport to Panama

Our best LATAM Airlines deals on Chicago Midway Airport to Panama flight tickets
LATAM Airlines
May 16
MDW5:10 pmChicago Midway
19h 40m
1 stop
PTY12:50 pmPanama City Tocumen Intl
May 20
PTY2:15 pmPanama City Tocumen Intl
19h 45m
1 stop
MDW10:00 amChicago Midway
$699
LATAM Airlines
Apr 25
MDW6:00 amChicago Midway
7h 02m
1 stop
PTY1:02 pmPanama City Tocumen Intl
Apr 30
PTY2:27 pmPanama City Tocumen Intl
8h 01m
1 stop
MDW10:28 pmChicago Midway
$700
LATAM Airlines
Aug 17
MDW6:00 amChicago Midway
7h 13m
1 stop
PTY1:13 pmPanama City Tocumen Intl
Aug 22
PTY2:28 pmPanama City Tocumen Intl
19h 22m
1 stop
MDW9:50 amChicago Midway
$702

Delta flights from Chicago Midway Airport to Panama

Our best Delta deals on Chicago Midway Airport to Panama flight tickets
Delta
May 2
MDW5:40 amChicago Midway
7h 22m
1 stop
PTY1:02 pmPanama City Tocumen Intl
May 6
PTY2:27 pmPanama City Tocumen Intl
8h 01m
1 stop
MDW10:28 pmChicago Midway
$610
Delta
May 2
MDW5:40 amChicago Midway
7h 22m
1 stop
PTY1:02 pmPanama City Tocumen Intl
May 6
PTY2:27 pmPanama City Tocumen Intl
8h 01m
1 stop
MDW10:28 pmChicago Midway
$630
Delta
Apr 28
MDW9:27 amChicago Midway
27h 35m
2 stops
PTY1:02 pmPanama City Tocumen Intl
May 29
PTY2:15 pmPanama City Tocumen Intl
18h 28m
2 stops
MDW8:43 amChicago Midway
$634

momondo Fare Finder

 
Customize your flight search to find flights from Chicago Midway Airport to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated March 6, 2026.
Use the filters below to find and compare flights from Chicago Midway Airport to Panama that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

ChicagoPanama City

MDW - PTY

MDWPTY

Chicago Midway

Sat 4/18

6:00 am-8:34 pm

1 stop14h 34m

Panama City Tocumen Intl

Sat 4/25

10:26 am-6:37 pm

1 stop8h 11m

$556

ChicagoPanama City

MDW - PTY

MDWPTY

Chicago Midway

Sat 4/11

6:30 am-1:55 am

3 stops19h 25m

Panama City Tocumen Intl

Tue 4/21

10:26 am-7:31 pm

1 stop9h 05m

$573

ChicagoPanama City

MDW - PTY

MDWPTY

Chicago Midway

Tue 5/5

6:00 am-8:34 pm

1 stop14h 34m

Panama City Tocumen Intl

Tue 5/12

9:33 pm-7:31 pm

2 stops21h 58m

$574

ChicagoPanama City

MDW - PTY

MDWPTY

Chicago Midway

Mon 4/13

6:30 am-2:30 pm

1 stop8h 00m

Panama City Tocumen Intl

Sat 5/2

10:25 am-10:14 pm

2 stops11h 49m

$581

ChicagoPanama City

MDW - PTY

MDWPTY

Chicago Midway

Thu 4/16

6:00 am-8:34 pm

1 stop14h 34m

Panama City Tocumen Intl

Mon 4/20

9:33 pm-7:31 pm

2 stops21h 58m

$591

ChicagoPanama City

MDW - PTY

MDWPTY

Chicago Midway

Sat 4/11

6:30 am-7:20 pm

1 stop12h 50m

Panama City Tocumen Intl

Wed 4/15

10:10 am-8:04 am

2 stops21h 54m

$601

ChicagoPanama City

MDW - PTY

MDWPTY

Chicago Midway

Sat 4/18

7:34 pm-8:34 pm

1 stop25h 00m

Panama City Tocumen Intl

Sat 4/25

10:25 am-10:14 pm

2 stops11h 49m

$605
Quickest round-trip

ChicagoPanama City

MDW - PTY

MDWPTY

Chicago Midway

Sun 4/19

6:00 am-1:02 pm

1 stop7h 02m

Panama City Tocumen Intl

Sat 4/25

2:27 pm-10:28 pm

1 stop8h 01m

$610

ChicagoPanama City

MDW - PTY

MDWPTY

Chicago Midway

Wed 4/22

2:15 pm-8:06 am

2 stops17h 51m

Panama City Tocumen Intl

Mon 4/27

10:26 am-10:19 pm

1 stop11h 53m

$612

ChicagoPanama City

MDW - PTY

MDWPTY

Chicago Midway

Sat 5/2

5:40 am-1:02 pm

1 stop7h 22m

Panama City Tocumen Intl

Wed 5/6

2:27 pm-10:28 pm

1 stop8h 01m

$630

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Panama from

How to get the cheapest flight ticket from Chicago Midway Airport to Panama

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest airline that flies from Chicago Midway to Panama?

Delta is the most popular carrier operating from Chicago Midway to Panama

Cheap Chicago Midway Airport to Panama flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Chicago Midway Airport to Panama

Fastest flight time

7h 03m

Direct flights

None
The fastest flight from Chicago Midway Airport to Panama takes 7h 03m
There are no direct flights from Chicago Midway Airport to Panama. There are no popular flight routes from Chicago Midway Airport to Panama.
Search flight deals

  • When did momondo last update prices for flights from Chicago Midway Airport to Panama?

    Prices for flights from Chicago Midway Airport to Panama are refreshed on a daily basis.

  • How old do you have to be to fly from Chicago Midway Airport to Panama?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Chicago Midway Airport to Panama.

  • What documentation or ID do you need to fly to Panama?

    The necessary travel and health documents for your Panama trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Why use momondo?

Why should I use momondo to find a flight deal from Chicago to Panama?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Chicago to Panama. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Chicago to Panama with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Chicago to Panama flights to just show those with flexible booking policies.

How can momondo help me find flights from Chicago to Panama?

momondo provides multiple filters to help you find the best flight to Panama from Chicago. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Chicago to Panama right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Chicago to Panama flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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