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Cheap flights from Chicago Midway Airport to Panama from $231

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Chicago Midway Airport to Panama departing on 11/15. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Chicago Midway Airport to Panama

Cheap round-trip flights

Enter your travel dates to find the best prices.
Delta Logo
6:00 am - 2:12 pmMDW-PTY
7h 12m1 stop
Delta Logo
3:37 pm - 11:40 pmPTY-MDW
9h 03m1 stop
$466Delta
Find Deal
Wed, Nov 19 - Sat, Nov 22
Delta Logo
9:34 am - 7:59 pmMDW-PTY
9h 25m2 stops
Delta Logo
3:46 pm - 11:47 pmPTY-MDW
9h 01m1 stop
$470Delta
Find Deal
Fri, Dec 5 - Wed, Dec 10
Delta Logo
5:31 pm - 1:55 pmMDW-PTY
19h 24m1 stop
Delta Logo
3:20 pm - 10:26 pmPTY-MDW
8h 06m1 stop
$474Delta
Find Deal
Mon, Jan 12 - Tue, Jan 27
Delta Logo
5:31 pm - 1:55 pmMDW-PTY
19h 24m1 stop
Delta Logo
3:20 pm - 12:48 pmPTY-MDW
22h 28m2 stops
$479Delta
Find Deal
Mon, Jan 12 - Tue, Jan 27
Delta Logo
5:31 pm - 1:55 pmMDW-PTY
19h 24m1 stop
Delta Logo
3:20 pm - 12:01 pmPTY-MDW
21h 41m1 stop
$482Delta
Find Deal
Mon, Jan 12 - Thu, Jan 29
Multiple Airlines Logo
2:16 pm - 8:06 amMDW-PTY
16h 50m1 stop
Multiple Airlines Logo
9:45 am - 9:53 pmPTY-MDW
13h 08m2 stops
$519Multiple Airlines
Find Deal
Thu, Dec 4 - Thu, Dec 11
Multiple Airlines Logo
2:16 pm - 12:40 amMDW-PTY
33h 24m2 stops
Multiple Airlines Logo
2:55 am - 9:53 pmPTY-MDW
19h 58m2 stops
$525Multiple Airlines
Find Deal
Thu, Dec 4 - Wed, Dec 10
Multiple Airlines Logo
2:16 pm - 8:40 amMDW-PTY
17h 24m1 stop
Multiple Airlines Logo
10:25 am - 9:53 pmPTY-MDW
12h 28m1 stop
$563Multiple Airlines
Find Deal
Thu, Dec 4 - Thu, Dec 11
Multiple Airlines Logo
2:16 pm - 8:40 amMDW-PTY
17h 24m1 stop
Multiple Airlines Logo
7:31 am - 10:18 pmPTY-MDW
15h 47m2 stops
$581Multiple Airlines
Find Deal
Thu, Dec 4 - Mon, Dec 8
Delta Logo
6:00 am - 12:55 pmMDW-PTY
6h 55m1 stop
Delta Logo
2:20 pm - 9:56 amPTY-MDW
19h 36m1 stop
$587Delta
Find Deal
Tue, Mar 10 - Wed, Mar 11

Delta flights from Chicago Midway Airport to Panama

Our best Delta deals on Chicago Midway Airport to Panama flight tickets
Delta
Nov 19
MDW6:00 amChicago Midway
7h 12m
1 stop
PTY2:12 pmPanama City Tocumen Intl
Nov 22
PTY3:37 pmPanama City Tocumen Intl
9h 03m
1 stop
MDW11:40 pmChicago Midway
$466
Find similar
Delta
Dec 5
MDW9:34 amChicago Midway
9h 25m
2 stops
PTY7:59 pmPanama City Tocumen Intl
Dec 10
PTY3:46 pmPanama City Tocumen Intl
9h 01m
1 stop
MDW11:47 pmChicago Midway
$470
Find similar
Delta
Jan 12
MDW5:31 pmChicago Midway
19h 24m
1 stop
PTY1:55 pmPanama City Tocumen Intl
Jan 27
PTY3:20 pmPanama City Tocumen Intl
8h 06m
1 stop
MDW10:26 pmChicago Midway
$474
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Chicago Midway Airport to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated November 4, 2025.
Use the filters below to find and compare flights from Chicago Midway Airport to Panama that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

ChicagoPanama City

MDW - PTY

MDWPTY

Chicago Midway

Wed 11/19

6:00 am-2:12 pm

1 stop7h 12m

Panama City Tocumen Intl

Sat 11/22

3:37 pm-11:40 pm

1 stop9h 03m

$466

ChicagoPanama City

MDW - PTY

MDWPTY

Chicago Midway

Fri 12/5

9:34 am-7:59 pm

2 stops9h 25m

Panama City Tocumen Intl

Wed 12/10

3:46 pm-11:47 pm

1 stop9h 01m

$470

ChicagoPanama City

MDW - PTY

MDWPTY

Chicago Midway

Mon 1/12

5:31 pm-1:55 pm

1 stop19h 24m

Panama City Tocumen Intl

Tue 1/27

3:20 pm-10:26 pm

1 stop8h 06m

$474

ChicagoPanama City

MDW - PTY

MDWPTY

Chicago Midway

Mon 1/12

5:31 pm-1:55 pm

1 stop19h 24m

Panama City Tocumen Intl

Tue 1/27

3:20 pm-12:48 pm

2 stops22h 28m

$479

ChicagoPanama City

MDW - PTY

MDWPTY

Chicago Midway

Mon 1/12

5:31 pm-1:55 pm

1 stop19h 24m

Panama City Tocumen Intl

Thu 1/29

3:20 pm-12:01 pm

1 stop21h 41m

$482

ChicagoPanama City

MDW - PTY

MDWPTY

Chicago Midway

Thu 12/4

2:16 pm-8:06 am

1 stop16h 50m

Panama City Tocumen Intl

Thu 12/11

9:45 am-9:53 pm

2 stops13h 08m

$519

ChicagoPanama City

MDW - PTY

MDWPTY

Chicago Midway

Thu 12/4

2:16 pm-12:40 am

2 stops33h 24m

Panama City Tocumen Intl

Wed 12/10

2:55 am-9:53 pm

2 stops19h 58m

$525

ChicagoPanama City

MDW - PTY

MDWPTY

Chicago Midway

Thu 12/4

2:16 pm-8:40 am

1 stop17h 24m

Panama City Tocumen Intl

Thu 12/11

10:25 am-9:53 pm

1 stop12h 28m

$563

ChicagoPanama City

MDW - PTY

MDWPTY

Chicago Midway

Thu 12/4

2:16 pm-8:40 am

1 stop17h 24m

Panama City Tocumen Intl

Mon 12/8

7:31 am-10:18 pm

2 stops15h 47m

$581

ChicagoPanama City

MDW - PTY

MDWPTY

Chicago Midway

Tue 3/10

6:00 am-12:55 pm

1 stop6h 55m

Panama City Tocumen Intl

Wed 3/11

2:20 pm-9:56 am

1 stop19h 36m

$587

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Chicago Midway Airport to Panama

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest airline that flies from Chicago Midway to Panama?

Delta and WestJet are the most popular carriers operating from Chicago Midway to Panama

Cheap Chicago Midway Airport to Panama flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Chicago Midway Airport to Panama

Direct flights

None
There are no direct flights from Chicago Midway Airport to Panama. There are no popular flight routes from Chicago Midway Airport to Panama.
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  • When did momondo last update prices for flights from Chicago Midway Airport to Panama?

    Prices for flights from Chicago Midway Airport to Panama are refreshed on a daily basis.

  • How old do you have to be to fly from Chicago Midway Airport to Panama?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Chicago Midway Airport to Panama.

  • What documentation or ID do you need to fly to Panama?

    The necessary travel and health documents for your Panama trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Why use momondo?

Why should I use momondo to find a flight deal from Chicago to Panama?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Chicago to Panama. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Chicago to Panama with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Chicago to Panama flights to just show those with flexible booking policies.

How can momondo help me find flights from Chicago to Panama?

momondo provides multiple filters to help you find the best flight to Panama from Chicago. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Chicago to Panama right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Chicago to Panama flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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