Cheap flights from Mexico City to Medellín from $166

The month of February is, on average, the cheapest month to fly to Medellín from Mexico City, with most prices found around $330. If you aren’t able to travel to Medellín during the month of February, then flying in March is also cheap. Prices for this month can be found on momondo for an average of $359.

The cheapest day to depart from Mexico City to Medellín is on a Sunday. Travelers who choose to depart for Medellín on a Sunday will often find tickets for as low as $420. Flights from Mexico City to Medellín on a Monday will generally be more expensive and average around $494. Keep in mind that these prices on both days could fluctuate depending on the season and the demand.

Our data shows that the cheapest Mexico City to Medellín flights are usually those with departure times in the evening. Our users have found flights to Medellín in the evening for as low as $416. In contrast, the most expensive time of day to depart to Medellín is in the morning when prices are around $480.

Fly from Mexico City Benito Juarez to Medellín Jose Maria Cordova Intl for the best Mexico City Benito Juarez - Medellín flight prices

You are more likely to see cheaper flights to Medellín from Mexico City when booking weeks ahead of your departure date. In general, you can expect to find flights to Medellín for around $395 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Medellín from Mexico City for as low as $367 on momondo.

There are 3 cabin classes available to choose from on Mexico City to Medellín flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Copa Airlines is the most popular carrier operating from Mexico City Benito Juarez to Medellín

Avianca, Aeromexico and Copa Airlines are the top three most popular airlines that fly to Medellín from Mexico City according to our data. Avianca is the first choice among our users, with 61% of people opting to fly with this airline when traveling to Medellín. Keep in mind that there are 4 different airlines that fly to Medellín on a routine basis, so you have a few additional options to choose from.

Historically, on average around 6% of flights between Mexico City and Medellín have experienced a delay on any given week. The average delay length over the past 12 months has been 129 minutes.

Generally, flights departing at night tend to experience fewer delays. Flights in the evening have, in the past, seen delays more frequently in comparison.

Sunday is statistically the day of the week which experiences the fewest number of delays on this flight route. Wednesday has historically seen more delays on average compared to the rest of the week.

According to our data, Avianca have had the least number of delays on this route over the last 12 months; with about 3% of their flights experiencing any sort of delay.

4 flights are operational daily from Mexico City to Medellín as of September 2026. The most popular departure time for this route is 5:00AM, with 64% of flights per day taking off in the morning.

28 flights are operational weekly from Mexico City to Medellín as of September 2026. The most popular departure day for this route is Mon, with 14% of flights per week taking off on this day.