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Cheap flights from Mexico City Federal District to Des Moines from $245

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Mexico City Federal District to Des Moines departing on 6/15. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Find the cheapest flights from Mexico City Federal District to Des Moines

Cheap round-trip flights

Enter your travel dates to find the best prices.
Frontier Logo
4:10 pm - 1:09 pm
MEX
-
DSM
43h 59m
2 stops
Frontier Logo
2:16 pm - 5:30 pm
DSM
-
MEX
28h 14m
1 stop
$437Frontier
Wed, Apr 29 - Wed, May 6
Multiple Airlines Logo
8:30 am - 2:19 pm
MEX
-
DSM
28h 49m
2 stops
Multiple Airlines Logo
9:44 pm - 12:00 am
DSM
-
MEX
51h 16m
2 stops
$489Multiple Airlines
Wed, May 27 - Sun, Aug 16
Multiple Airlines Logo
8:10 am - 9:24 pm
MEX
-
DSM
12h 14m
2 stops
Multiple Airlines Logo
10:01 pm - 8:05 pm
DSM
-
MEX
23h 04m
1 stop
$514Multiple Airlines
Fri, May 1 - Fri, May 8
Frontier Logo
7:55 pm - 1:09 pm
MEX
-
DSM
40h 14m
2 stops
Frontier Logo
2:16 pm - 10:45 pm
DSM
-
MEX
33h 29m
2 stops
$525Frontier
Wed, Apr 29 - Wed, May 6
Multiple Airlines Logo
4:10 pm - 11:24 pm
MEX
-
DSM
30h 14m
2 stops
Multiple Airlines Logo
12:37 pm - 10:15 pm
DSM
-
MEX
10h 38m
1 stop
$549Multiple Airlines
Sun, May 24 - Fri, Aug 14
Multiple Airlines Logo
11:00 am - 9:24 pm
MEX
-
DSM
9h 24m
1 stop
Multiple Airlines Logo
10:01 pm - 8:05 pm
DSM
-
MEX
23h 04m
1 stop
$550Multiple Airlines
Fri, May 1 - Fri, May 8
United Airlines Logo
4:40 am - 10:43 pm
MEX
-
DSM
17h 03m
1 stop
United Airlines Logo
5:00 am - 12:45 pm
DSM
-
MEX
8h 45m
1 stop
$557United Airlines
Mon, Apr 27 - Mon, May 4
United Airlines Logo
9:35 am - 8:30 pm
MEX
-
DSM
9h 55m
2 stops
United Airlines Logo
5:16 pm - 9:10 pm
DSM
-
MEX
28h 54m
1 stop
$564United Airlines
Wed, May 27 - Sun, Aug 16
United Airlines Logo
6:30 am - 11:42 pm
MEX
-
DSM
16h 12m
2 stops
United Airlines Logo
7:16 pm - 8:35 am
DSM
-
MEX
14h 19m
2 stops
$566United Airlines
Thu, Apr 16 - Sun, Apr 19
Multiple Airlines Logo
8:40 am - 1:31 pm
MEX
-
DSM
27h 51m
1 stop
Multiple Airlines Logo
12:37 pm - 10:15 pm
DSM
-
MEX
10h 38m
1 stop
$567Multiple Airlines
Sun, May 24 - Fri, Aug 14

Frontier flights from Mexico City Federal District to Des Moines

Our best Frontier deals on Mexico City Federal District to Des Moines flight tickets
Frontier
Apr 29
MEX4:10 pmMexico City Benito Juarez
43h 59m
2 stops
DSM1:09 pmDes Moines
May 6
DSM2:16 pmDes Moines
28h 14m
1 stop
MEX5:30 pmMexico City Benito Juarez
$437
Frontier
Apr 29
MEX7:55 pmMexico City Benito Juarez
40h 14m
2 stops
DSM1:09 pmDes Moines
May 6
DSM2:16 pmDes Moines
33h 29m
2 stops
MEX10:45 pmMexico City Benito Juarez
$525
Frontier
May 24
MEX7:00 amMexico City Benito Juarez
29h 31m
2 stops
DSM1:31 pmDes Moines
Aug 14
DSM8:21 pmDes Moines
22h 09m
1 stop
MEX5:30 pmMexico City Benito Juarez
$605

American Airlines flights from Mexico City Federal District to Des Moines

Our best American Airlines deals on Mexico City Federal District to Des Moines flight tickets
American Airlines
Apr 29
MEX1:10 pmMexico City Benito Juarez
20h 16m
1 stop
DSM10:26 amDes Moines
May 6
DSM5:00 amDes Moines
14h 32m
1 stop
MEX6:32 pmMexico City Benito Juarez
$566
American Airlines
May 24
MEX7:00 amMexico City Benito Juarez
10h 22m
1 stop
DSM6:22 pmDes Moines
Aug 14
DSM6:30 amDes Moines
10h 41m
1 stop
MEX4:11 pmMexico City Benito Juarez
$604
American Airlines
May 24
MEX5:00 amMexico City Benito Juarez
12h 22m
1 stop
DSM6:22 pmDes Moines
Aug 14
DSM6:30 amDes Moines
13h 08m
1 stop
MEX6:38 pmMexico City Benito Juarez
$618

momondo Fare Finder

 
Customize your flight search to find flights from Mexico City Federal District to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated March 18, 2026.
Use the filters below to find and compare flights from Mexico City Federal District to Des Moines that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Mexico CityDes Moines

MEX - DSM

MEXDSM

Mexico City Benito Juarez

Wed 4/29

4:10 pm-1:09 pm

2 stops43h 59m

Des Moines

Wed 5/6

2:16 pm-5:30 pm

1 stop28h 14m

$437

Mexico CityDes Moines

MEX - DSM

MEXDSM

Mexico City Benito Juarez

Wed 5/27

8:30 am-2:19 pm

2 stops28h 49m

Des Moines

Sun 8/16

9:44 pm-12:00 am

2 stops51h 16m

$489

Mexico CityDes Moines

MEX - DSM

MEXDSM

Mexico City Benito Juarez

Fri 5/1

8:10 am-9:24 pm

2 stops12h 14m

Des Moines

Fri 5/8

10:01 pm-8:05 pm

1 stop23h 04m

$514

Mexico CityDes Moines

MEX - DSM

MEXDSM

Mexico City Benito Juarez

Wed 4/29

7:55 pm-1:09 pm

2 stops40h 14m

Des Moines

Wed 5/6

2:16 pm-10:45 pm

2 stops33h 29m

$525

Mexico CityDes Moines

MEX - DSM

MEXDSM

Mexico City Benito Juarez

Sun 5/24

4:10 pm-11:24 pm

2 stops30h 14m

Des Moines

Fri 8/14

12:37 pm-10:15 pm

1 stop10h 38m

$549

Mexico CityDes Moines

MEX - DSM

MEXDSM

Mexico City Benito Juarez

Fri 5/1

11:00 am-9:24 pm

1 stop9h 24m

Des Moines

Fri 5/8

10:01 pm-8:05 pm

1 stop23h 04m

$550
Quickest round-trip

Mexico CityDes Moines

MEX - DSM

MEXDSM

Mexico City Benito Juarez

Mon 4/27

4:40 am-10:43 pm

1 stop17h 03m

Des Moines

Mon 5/4

5:00 am-12:45 pm

1 stop8h 45m

$557

Mexico CityDes Moines

MEX - DSM

MEXDSM

Mexico City Benito Juarez

Wed 5/27

9:35 am-8:30 pm

2 stops9h 55m

Des Moines

Sun 8/16

5:16 pm-9:10 pm

1 stop28h 54m

$564

Mexico CityDes Moines

MEX - DSM

MEXDSM

Mexico City Benito Juarez

Thu 4/16

6:30 am-11:42 pm

2 stops16h 12m

Des Moines

Sun 4/19

7:16 pm-8:35 am

2 stops14h 19m

$566

Mexico CityDes Moines

MEX - DSM

MEXDSM

Mexico City Benito Juarez

Sun 5/24

8:40 am-1:31 pm

1 stop27h 51m

Des Moines

Fri 8/14

12:37 pm-10:15 pm

1 stop10h 38m

$567

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Des Moines from

How to get the cheapest flight ticket from Mexico City Federal District to Des Moines

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Des Moines?

If you’re not able to fly to Des Moines in February, then September is your next best option. Flight prices from Mexico City Federal District to Des Moines during September average around $486.

Can stopping save me money on Mexico City Federal District to Des Moines flights?

You could potentially save up to 4% on your flight if you consider stops on a Mexico City Federal District to Des Moines flight.

Cheap Mexico City Federal District to Des Moines flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Mexico City Federal District to Des Moines

Fastest flight time

7h 10m

Direct flights

None
The fastest flight from Mexico City Federal District to Des Moines takes 7h 10m
There are no direct flights from Mexico City Federal District to Des Moines. There are no popular flight routes from Mexico City Federal District to Des Moines.
Search flight deals

  • When did momondo last update prices for flights from Mexico City Federal District to Des Moines Airport?

    Prices for flights from Mexico City Federal District to Des Moines Airport refresh daily.

  • How old do you have to be to fly from Mexico City Federal District to Des Moines Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Mexico City Federal District to Des Moines Airport.

  • What documentation or ID do you need to fly to Des Moines Airport?

    The necessary travel and health documents for your Des Moines Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
West Des Moines
Ames
Ankeny
Altoona
Clive
Urbandale
Pella
Johnston
Newton
Osceola
Boone
Grinnell
Oskaloosa
Norwalk
Carlisle

Why use momondo?

Why should I use momondo to find a flight deal from Mexico City Federal District to Des Moines?

Finding the right flight to Des Moines from Mexico City Federal District is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Des Moines quick and easy, saving you time and money.

Can I find flights from Mexico City Federal District to Des Moines with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Des Moines from Mexico City Federal District with this policy.

How can momondo help me find flights from Mexico City Federal District to Des Moines?

momondo provides multiple filters to help you find the best flight to Des Moines from Mexico City Federal District. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Mexico City Federal District to Des Moines right now. Can momondo alert me if prices change?

Price alerts on flights to Des Moines from Mexico City Federal District are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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