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Cheap flights from New York LaGuardia Airport to Des Moines from $104

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from New York LaGuardia Airport to Des Moines departing on 5/27. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from New York LaGuardia Airport to Des Moines

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
4:59 pm - 10:51 pm
LGA
-
DSM
30h 52m
1 stop
Multiple Airlines Logo
8:30 am - 4:57 pm
DSM
-
LGA
31h 27m
2 stops
$248Multiple Airlines
Wed, Mar 4 - Sun, Mar 22
Multiple Airlines Logo
12:59 pm - 11:12 pm
LGA
-
DSM
11h 13m
1 stop
Multiple Airlines Logo
9:00 am - 3:59 pm
DSM
-
LGA
53h 59m
2 stops
$250Multiple Airlines
Thu, Feb 19 - Sun, Feb 22
Multiple Airlines Logo
4:59 pm - 10:51 pm
LGA
-
DSM
30h 52m
1 stop
Multiple Airlines Logo
8:30 am - 2:00 pm
DSM
-
LGA
28h 30m
1 stop
$256Multiple Airlines
Wed, Mar 4 - Sun, Mar 22
Multiple Airlines Logo
4:59 pm - 9:06 am
LGA
-
DSM
17h 07m
1 stop
Multiple Airlines Logo
8:21 pm - 3:43 pm
DSM
-
LGA
18h 22m
2 stops
$259Multiple Airlines
Wed, Mar 11 - Mon, Mar 16
Multiple Airlines Logo
7:59 am - 8:14 pm
LGA
-
DSM
13h 15m
1 stop
Multiple Airlines Logo
10:56 am - 11:29 am
DSM
-
LGA
23h 33m
1 stop
$303Multiple Airlines
Thu, Mar 12 - Tue, Mar 17
Multiple Airlines Logo
12:59 pm - 10:51 pm
LGA
-
DSM
10h 52m
1 stop
Multiple Airlines Logo
7:00 am - 10:00 am
DSM
-
LGA
26h 00m
2 stops
$305Multiple Airlines
Thu, Mar 5 - Sun, Mar 8
Multiple Airlines Logo
8:00 am - 10:06 pm
LGA
-
DSM
15h 06m
1 stop
Multiple Airlines Logo
8:14 pm - 10:35 pm
DSM
-
LGA
25h 21m
2 stops
$310Multiple Airlines
Thu, Apr 9 - Fri, Apr 10
American Airlines Logo
9:00 am - 1:05 pm
LGA
-
DSM
5h 05m
1 stop
American Airlines Logo
7:45 am - 11:29 am
DSM
-
LGA
2h 44mnonstop
$317American Airlines
Wed, Mar 18 - Tue, Mar 24
Multiple Airlines Logo
10:55 pm - 7:16 pm
LGA
-
DSM
21h 21m
2 stops
Multiple Airlines Logo
6:00 am - 7:35 pm
DSM
-
LGA
12h 35m
1 stop
$323Multiple Airlines
Tue, Mar 24 - Thu, Mar 26
American Airlines Logo
5:40 pm - 7:57 pm
LGA
-
DSM
3h 17mnonstop
American Airlines Logo
1:37 pm - 11:59 pm
DSM
-
LGA
9h 22m
1 stop
$324American Airlines
Tue, Mar 31 - Mon, Apr 6

Delta flights from New York LaGuardia Airport to Des Moines

Our best Delta deals on New York LaGuardia Airport to Des Moines flight tickets
Delta
Apr 7
LGA5:15 pmNew York LaGuardia
3h 12m
DSM7:27 pmDes Moines
Apr 12
DSM9:22 amDes Moines
2h 38m
LGA1:00 pmNew York LaGuardia
$362
Delta
Apr 24
LGA5:15 pmNew York LaGuardia
3h 13m
DSM7:28 pmDes Moines
Apr 26
DSM9:15 amDes Moines
2h 40m
LGA12:55 pmNew York LaGuardia
$377
Delta
Mar 4
LGA5:15 pmNew York LaGuardia
3h 18m
DSM7:33 pmDes Moines
Mar 22
DSM9:15 amDes Moines
2h 38m
LGA12:53 pmNew York LaGuardia
$386

Southwest flights from New York LaGuardia Airport to Des Moines

Our best Southwest deals on New York LaGuardia Airport to Des Moines flight tickets
Southwest
Apr 1
LGA6:50 amNew York LaGuardia
5h 50m
1 stop
DSM11:40 amDes Moines
Apr 9
DSM6:50 amDes Moines
8h 00m
2 stops
LGA3:50 pmNew York LaGuardia
$346
Southwest
Apr 7
LGA2:15 pmNew York LaGuardia
8h 00m
1 stop
DSM9:15 pmDes Moines
Apr 12
DSM5:20 amDes Moines
5h 00m
1 stop
LGA11:20 amNew York LaGuardia
$372
Southwest
Apr 1
LGA10:15 amNew York LaGuardia
11h 35m
2 stops
DSM8:50 pmDes Moines
Apr 9
DSM6:50 amDes Moines
8h 00m
2 stops
LGA3:50 pmNew York LaGuardia
$378

momondo Fare Finder

 
Customize your flight search to find flights from New York LaGuardia Airport to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated February 8, 2026.
Use the filters below to find and compare flights from New York LaGuardia Airport to Des Moines that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

New YorkDes Moines

LGA - DSM

LGADSM

New York LaGuardia

Wed 3/4

4:59 pm-10:51 pm

1 stop30h 52m

Des Moines

Sun 3/22

8:30 am-4:57 pm

2 stops31h 27m

$248

New YorkDes Moines

LGA - DSM

LGADSM

New York LaGuardia

Thu 2/19

12:59 pm-11:12 pm

1 stop11h 13m

Des Moines

Sun 2/22

9:00 am-3:59 pm

2 stops53h 59m

$250

New YorkDes Moines

LGA - DSM

LGADSM

New York LaGuardia

Wed 3/4

4:59 pm-10:51 pm

1 stop30h 52m

Des Moines

Sun 3/22

8:30 am-2:00 pm

1 stop28h 30m

$256

New YorkDes Moines

LGA - DSM

LGADSM

New York LaGuardia

Wed 3/11

4:59 pm-9:06 am

1 stop17h 07m

Des Moines

Mon 3/16

8:21 pm-3:43 pm

2 stops18h 22m

$259

New YorkDes Moines

LGA - DSM

LGADSM

New York LaGuardia

Thu 3/12

7:59 am-8:14 pm

1 stop13h 15m

Des Moines

Tue 3/17

10:56 am-11:29 am

1 stop23h 33m

$303

New YorkDes Moines

LGA - DSM

LGADSM

New York LaGuardia

Thu 3/5

12:59 pm-10:51 pm

1 stop10h 52m

Des Moines

Sun 3/8

7:00 am-10:00 am

2 stops26h 00m

$305

New YorkDes Moines

LGA - DSM

LGADSM

New York LaGuardia

Thu 4/9

8:00 am-10:06 pm

1 stop15h 06m

Des Moines

Fri 4/10

8:14 pm-10:35 pm

2 stops25h 21m

$310

New YorkDes Moines

LGA - DSM

LGADSM

New York LaGuardia

Wed 3/18

9:00 am-1:05 pm

1 stop5h 05m

Des Moines

Tue 3/24

7:45 am-11:29 am

Nonstop2h 44m

$317

New YorkDes Moines

LGA - DSM

LGADSM

New York LaGuardia

Tue 3/24

10:55 pm-7:16 pm

2 stops21h 21m

Des Moines

Thu 3/26

6:00 am-7:35 pm

1 stop12h 35m

$323

New YorkDes Moines

LGA - DSM

LGADSM

New York LaGuardia

Tue 3/31

5:40 pm-7:57 pm

Nonstop3h 17m

Des Moines

Mon 4/6

1:37 pm-11:59 pm

1 stop9h 22m

$324

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Des Moines from

How to get the cheapest flight ticket from New York LaGuardia Airport to Des Moines

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Des Moines?

If you’re not able to fly to Des Moines in March, then May is your next best option. Flight prices from New York LaGuardia Airport to Des Moines during May average around $352.

What is the cheapest day to depart on your flight to Des Moines?

The cheapest day to depart from New York LaGuardia Airport to Des Moines is on a Friday. Travelers who choose to depart for Des Moines on a Friday will often find tickets for as low as $274. Flights from New York LaGuardia Airport to Des Moines on a Sunday will generally be more expensive and average around $448. Keep in mind that these prices on both days could fluctuate depending on the season and the demand.

What is the cheapest time of day to depart on your flight to Des Moines?

According to our data, the cheapest time of day to fly to Des Moines is in the morning. momondo users have found flights departing from New York LaGuardia Airport to Des Moines in the morning for as low as $312. Keep in mind that these prices may fluctuate based on what airline you choose and the time of year you plan to travel. Try not to purchase tickets at noon because they tend to be around $423. Of course, these prices can vary depending on the time of year and what airport you fly to.

What is the cheapest New York LaGuardia to Des Moines flight route?

Fly from New York LaGuardia to Des Moines for the best New York LaGuardia - Des Moines flight prices

What cabin class options are available on New York LaGuardia to Des Moines flights?

There are 4 cabin classes available to choose from on New York LaGuardia to Des Moines flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on New York LaGuardia Airport to Des Moines flights?

No. A direct flight is the cheapest option for a flight between New York LaGuardia Airport to Des Moines.

How have New York LaGuardia Airport to Des Moines flight prices changed over time?

As of February 2026, prices for New York LaGuardia Airport to Des Moines flights are approximately 3% cheaper when compared to flights at the same time last year.

When to book flights from New York LaGuardia Airport to Des Moines

Are you open to changing your travel dates? Check out the ideal times to fly from New York LaGuardia Airport to Des Moines according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap New York LaGuardia Airport to Des Moines (LGA to DSM) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from New York LaGuardia Airport to Des Moines

Best Price Found

$325

Fastest flight time

3h 04m

Direct flights

Every day

Airports in Des Moines

1 airport
The best one-way flight to Des Moines from New York LaGuardia Airport in the past 72 hours is $325. The best round-trip flight deal from New York LaGuardia Airport to Des Moines found on momondo in the last 72 hours is $421.
The fastest flight from New York LaGuardia Airport to Des Moines takes 3h 04m
Direct flights go from New York LaGuardia Airport to Des Moines every day.
There is 1 airport in Des Moines. From New York LaGuardia Airport there are direct flights to Des Moines (DSM).
Search flight deals

  • How far is New York LaGuardia to Des Moines by plane?

    A flight from New York LaGuardia to Des Moines will travel around 1025.9 mi. A reasonable flight in good conditions will take 3h 04m.

  • When did momondo last update prices for flights from New York LaGuardia Airport to Des Moines Airport?

    Prices for flights from New York LaGuardia Airport to Des Moines Airport are updated daily.

  • How many operators does momondo search for flights from New York LaGuardia Airport to Des Moines Airport?

  • How old do you have to be to fly from New York LaGuardia Airport to Des Moines Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from New York LaGuardia Airport to Des Moines Airport.

  • What documentation or ID do you need to fly to Des Moines Airport?

    The required travel and health documents for your Des Moines Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Des Moines Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular plane model from New York LaGuardia Airport to Des Moines?

  • What is the most popular airline from New York LaGuardia Airport to Des Moines?

Best airlines flying from New York LaGuardia Airport to Des Moines

Compare and see reviews for airlines that fly from New York LaGuardia Airport to Des Moines with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $255Free CancellationRating
7.2
11,249 reviews
Search American Airlines flights
DeltaPriceFrom $265Free CancellationRating
7.9
8,172 reviews
Search Delta flights

  • Delta Flights From New York LaGuardia Airport to Des Moines

    Delta is one of the most popular airlines flying from New York LaGuardia Airport to Des Moines, operating 5 flights/week on average for this route. A good Delta flight deal for New York LaGuardia Airport to Des Moines starts from $265 round-trip, up to an average price of $383. Our users have rated Delta at 7.9/10.

  • American Airlines Flights From New York LaGuardia Airport to Des Moines

    American Airlines (7.2/10 from 11,258 reviews) operates around 4 flights from New York LaGuardia Airport to Des Moines in any given week. The average American Airlines airfare for this route is around $346, with deals from around $255 rare but found on momondo. Referenced prices are for round-trip New York LaGuardia Airport to Des Moines flight searches in the last 72 hours.

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
West Des Moines
Ames
Ankeny
Altoona
Urbandale
Clive
Pella
Newton
Johnston
Boone
Osceola
Norwalk
Oskaloosa
Grinnell
Carlisle

Why use momondo?

Why should I use momondo to find a flight deal from New York to Des Moines?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from New York to Des Moines. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from New York to Des Moines with flexible booking policies on momondo?

All flight searches from New York to Des Moines on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from New York to Des Moines?

momondo helps you find the best flight between New York and Des Moines by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from New York to Des Moines right now. Can momondo alert me if prices change?

Price alerts on flights to Des Moines from New York are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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