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Cheap flights from New York LaGuardia Airport to Des Moines from $121

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from New York LaGuardia Airport to Des Moines departing on 6/4. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from New York LaGuardia Airport to Des Moines

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
6:29 am - 8:12 pm
LGA
-
DSM
38h 43m
2 stops
Multiple Airlines Logo
4:11 pm - 4:01 pm
DSM
-
LGA
22h 50m
1 stop
$315Multiple Airlines
Thu, May 28 - Tue, Jun 9
Multiple Airlines Logo
8:15 pm - 8:37 am
LGA
-
DSM
13h 22m
1 stop
Multiple Airlines Logo
2:16 pm - 11:14 pm
DSM
-
LGA
31h 58m
2 stops
$320Multiple Airlines
Wed, Jun 3 - Wed, Jun 10
Multiple Airlines Logo
8:29 pm - 8:37 am
LGA
-
DSM
13h 08m
1 stop
Multiple Airlines Logo
5:05 pm - 11:14 pm
DSM
-
LGA
29h 09m
2 stops
$337Multiple Airlines
Sat, Jun 13 - Mon, Jun 29
Multiple Airlines Logo
8:29 pm - 8:37 am
LGA
-
DSM
13h 08m
1 stop
Multiple Airlines Logo
5:06 pm - 4:01 pm
DSM
-
LGA
21h 55m
1 stop
$345Multiple Airlines
Sat, Jun 13 - Sat, Jun 27
Delta Logo
5:30 pm - 7:34 pm
LGA
-
DSM
3h 04mnonstop
Delta Logo
7:33 am - 11:18 am
DSM
-
LGA
2h 45mnonstop
$355Delta
Thu, May 28 - Tue, Jun 9
Multiple Airlines Logo
8:15 pm - 8:53 am
LGA
-
DSM
13h 38m
1 stop
Multiple Airlines Logo
3:57 pm - 8:56 pm
DSM
-
LGA
27h 59m
2 stops
$356Multiple Airlines
Wed, May 27 - Mon, Jun 1
Multiple Airlines Logo
8:29 pm - 8:37 am
LGA
-
DSM
13h 08m
1 stop
Multiple Airlines Logo
5:45 pm - 11:14 pm
DSM
-
LGA
28h 29m
2 stops
$363Multiple Airlines
Sat, Jun 13 - Mon, Jun 29
Delta Logo
5:30 pm - 7:34 pm
LGA
-
DSM
3h 04mnonstop
Delta Logo
2:25 pm - 9:25 pm
DSM
-
LGA
6h 00m
1 stop
$365Delta
Thu, May 28 - Tue, Jun 9
Multiple Airlines Logo
8:15 pm - 8:37 am
LGA
-
DSM
13h 22m
1 stop
Multiple Airlines Logo
10:53 am - 8:56 pm
DSM
-
LGA
33h 03m
2 stops
$370Multiple Airlines
Wed, Jun 3 - Sun, Jun 7
Southwest Logo
6:00 am - 11:45 am
LGA
-
DSM
6h 45m
1 stop
Southwest Logo
6:25 am - 4:55 pm
DSM
-
LGA
9h 30m
1 stop
$375Southwest
Thu, May 28 - Tue, Jun 9

American Airlines flights from New York LaGuardia Airport to Des Moines

Our best American Airlines deals on New York LaGuardia Airport to Des Moines flight tickets
American Airlines
May 20
LGA5:59 pmNew York LaGuardia
3h 22m
DSM8:21 pmDes Moines
Jun 2
DSM7:10 amDes Moines
2h 50m
LGA11:00 amNew York LaGuardia
$410
American Airlines
Jul 8
LGA6:29 pmNew York LaGuardia
3h 22m
DSM8:51 pmDes Moines
Jul 12
DSM7:01 amDes Moines
2h 49m
LGA10:50 amNew York LaGuardia
$411
American Airlines
May 20
LGA4:36 pmNew York LaGuardia
6h 17m
1 stop
DSM9:53 pmDes Moines
Jun 2
DSM7:10 amDes Moines
2h 50m
LGA11:00 amNew York LaGuardia
$420

Delta flights from New York LaGuardia Airport to Des Moines

Our best Delta deals on New York LaGuardia Airport to Des Moines flight tickets
Delta
May 28
LGA5:30 pmNew York LaGuardia
3h 04m
DSM7:34 pmDes Moines
Jun 9
DSM7:33 amDes Moines
2h 45m
LGA11:18 amNew York LaGuardia
$355
Delta
May 28
LGA5:30 pmNew York LaGuardia
3h 04m
DSM7:34 pmDes Moines
Jun 9
DSM2:25 pmDes Moines
6h 00m
1 stop
LGA9:25 pmNew York LaGuardia
$365
Delta
Jun 13
LGA9:40 amNew York LaGuardia
3h 04m
DSM11:44 amDes Moines
Jun 27
DSM6:03 pmDes Moines
4h 41m
1 stop
LGA11:44 pmNew York LaGuardia
$385

momondo Fare Finder

 
Customize your flight search to find flights from New York LaGuardia Airport to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated May 8, 2026.
Use the filters below to find and compare flights from New York LaGuardia Airport to Des Moines that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

New YorkDes Moines

LGA - DSM

LGADSM

New York LaGuardia

Thu 5/28

6:29 am-8:12 pm

2 stops38h 43m

Des Moines

Tue 6/9

4:11 pm-4:01 pm

1 stop22h 50m

$315

New YorkDes Moines

LGA - DSM

LGADSM

New York LaGuardia

Wed 6/3

8:15 pm-8:37 am

1 stop13h 22m

Des Moines

Wed 6/10

2:16 pm-11:14 pm

2 stops31h 58m

$320

New YorkDes Moines

LGA - DSM

LGADSM

New York LaGuardia

Sat 6/13

8:29 pm-8:37 am

1 stop13h 08m

Des Moines

Mon 6/29

5:05 pm-11:14 pm

2 stops29h 09m

$337

New YorkDes Moines

LGA - DSM

LGADSM

New York LaGuardia

Sat 6/13

8:29 pm-8:37 am

1 stop13h 08m

Des Moines

Sat 6/27

5:06 pm-4:01 pm

1 stop21h 55m

$345
Quickest round-trip

New YorkDes Moines

LGA - DSM

LGADSM

New York LaGuardia

Thu 5/28

5:30 pm-7:34 pm

Nonstop3h 04m

Des Moines

Tue 6/9

7:33 am-11:18 am

Nonstop2h 45m

$355

New YorkDes Moines

LGA - DSM

LGADSM

New York LaGuardia

Wed 5/27

8:15 pm-8:53 am

1 stop13h 38m

Des Moines

Mon 6/1

3:57 pm-8:56 pm

2 stops27h 59m

$356

New YorkDes Moines

LGA - DSM

LGADSM

New York LaGuardia

Sat 6/13

8:29 pm-8:37 am

1 stop13h 08m

Des Moines

Mon 6/29

5:45 pm-11:14 pm

2 stops28h 29m

$363

New YorkDes Moines

LGA - DSM

LGADSM

New York LaGuardia

Thu 5/28

5:30 pm-7:34 pm

Nonstop3h 04m

Des Moines

Tue 6/9

2:25 pm-9:25 pm

1 stop6h 00m

$365

New YorkDes Moines

LGA - DSM

LGADSM

New York LaGuardia

Wed 6/3

8:15 pm-8:37 am

1 stop13h 22m

Des Moines

Sun 6/7

10:53 am-8:56 pm

2 stops33h 03m

$370

New YorkDes Moines

LGA - DSM

LGADSM

New York LaGuardia

Thu 5/28

6:00 am-11:45 am

1 stop6h 45m

Des Moines

Tue 6/9

6:25 am-4:55 pm

1 stop9h 30m

$375

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Des Moines from

How to get the cheapest flight ticket from New York LaGuardia Airport to Des Moines

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between New York LaGuardia Airport and Des Moines?

What is the cheapest month to fly to Des Moines?

If you’re not able to fly to Des Moines in November, then September is your next best option. Flight prices from New York LaGuardia Airport to Des Moines during September average around $375.

What is the cheapest day to depart on your flight to Des Moines?

The cheapest day to depart from New York LaGuardia Airport to Des Moines is on a Friday. Travelers who choose to depart for Des Moines on a Friday will often find tickets for as low as $209. Flights from New York LaGuardia Airport to Des Moines on a Sunday will generally be more expensive and average around $582. Keep in mind that these prices on both days could fluctuate depending on the season and the demand.

What is the cheapest time of day to depart on your flight to Des Moines?

According to our data, the cheapest time of day to fly to Des Moines is in the morning. momondo users have found flights departing from New York LaGuardia Airport to Des Moines in the morning for as low as $295. Keep in mind that these prices may fluctuate based on what airline you choose and the time of year you plan to travel. Try not to purchase tickets in the afternoon because they tend to be around $451. Of course, these prices can vary depending on the time of year and what airport you fly to.

What is the cheapest New York LaGuardia to Des Moines flight route?

Fly from New York LaGuardia to Des Moines for the best New York LaGuardia - Des Moines flight prices

Can stopping save me money on New York LaGuardia Airport to Des Moines flights?

You could potentially save up to 19% on your flight if you consider stops on a New York LaGuardia Airport to Des Moines flight.

How have New York LaGuardia Airport to Des Moines flight prices changed over time?

As of May 2026, prices for New York LaGuardia Airport to Des Moines flights are approximately 1% more expensive when compared to flights at the same time last year.

When to book flights from New York LaGuardia Airport to Des Moines

Are you open to changing your travel dates? Check out the ideal times to fly from New York LaGuardia Airport to Des Moines according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap New York LaGuardia Airport to Des Moines (LGA to DSM) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from New York LaGuardia Airport to Des Moines

Best Price Found

$365

Fastest flight time

3h 04m

Direct flights

Every day

Airports in Des Moines

1 airport
The best one-way flight to Des Moines from New York LaGuardia Airport in the past 72 hours is $365. The best round-trip flight deal from New York LaGuardia Airport to Des Moines found on momondo in the last 72 hours is $460.
The fastest flight from New York LaGuardia Airport to Des Moines takes 3h 04m
Direct flights go from New York LaGuardia Airport to Des Moines every day.
There is 1 airport in Des Moines. From New York LaGuardia Airport there are direct flights to Des Moines (DSM).
Search flight deals

Frequently asked questions about flying from New York LaGuardia Airport to Des Moines

  • How far is New York LaGuardia to Des Moines by plane?

    A flight from New York LaGuardia to Des Moines will travel around 1025.9 mi. A reasonable flight in good conditions will take 3h 04m.

  • When did momondo last update prices for flights from New York LaGuardia Airport to Des Moines Airport?

    Prices for flights from New York LaGuardia Airport to Des Moines Airport are updated daily.

  • How many operators does momondo search for flights from New York LaGuardia Airport to Des Moines Airport?

  • How old do you have to be to fly from New York LaGuardia Airport to Des Moines Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from New York LaGuardia Airport to Des Moines Airport.

  • What documentation or ID do you need to fly to Des Moines Airport?

    The required travel and health documents for your Des Moines Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Des Moines Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular plane model from New York LaGuardia Airport to Des Moines?

  • What is the most popular airline from New York LaGuardia Airport to Des Moines?

Best airlines flying from New York LaGuardia Airport to Des Moines

Compare and see reviews for airlines that fly from New York LaGuardia Airport to Des Moines with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $265Free CancellationRating
7.9
8,459 reviews
Search Delta flights
American AirlinesPriceFrom $271Free CancellationRating
7.1
11,669 reviews
Search American Airlines flights

  • Delta Flights From New York LaGuardia Airport to Des Moines

    Delta is one of the most popular airlines flying from New York LaGuardia Airport to Des Moines, operating 5 flights/week on average for this route. A good Delta flight deal for New York LaGuardia Airport to Des Moines starts from $265 round-trip, up to an average price of $425. Our users have rated Delta at 7.9/10.

  • American Airlines Flights From New York LaGuardia Airport to Des Moines

    American Airlines (7.1/10 from 11,667 reviews) operates around 5 flights from New York LaGuardia Airport to Des Moines in any given week. The average American Airlines airfare for this route is around $441, with deals from around $271 rare but found on momondo. Referenced prices are for round-trip New York LaGuardia Airport to Des Moines flight searches in the last 72 hours.

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
West Des Moines
Ames
Ankeny
Altoona
Clive
Urbandale
Pella
Johnston
Newton
Osceola
Boone
Grinnell
Oskaloosa
Norwalk
Carlisle

Why use momondo?

Why should I use momondo to find a flight deal from New York to Des Moines?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from New York to Des Moines. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from New York to Des Moines with flexible booking policies on momondo?

All flight searches from New York to Des Moines on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from New York to Des Moines?

momondo helps you find the best flight between New York and Des Moines by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from New York to Des Moines right now. Can momondo alert me if prices change?

Price alerts on flights to Des Moines from New York are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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