Latest deals
Insights
When to book
FAQs
Reviews
Price Alerts

Cheap flights from Knoxville to Rome from $332

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Knoxville to Rome departing on 9/24. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

Discover deals from 900+ travel sites with momondo.

Save money when you book flights with momondo

Big names and deals

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Price Alerts

Not ready to book? to track prices.
Search flight deals

Find the cheapest flights from Knoxville to Rome (TYS-ROM)

Cheap round-trip flights

United Airlines Logo
8:26 am - 7:45 amTYS-FCO
17h 19m1 stop
United Airlines Logo
1:15 pm - 2:43 pmFCO-TYS
31h 28m2 stops
$582United Airlines
Find Deal
Wed, Nov 12 - Fri, Nov 21
United Airlines Logo
9:55 am - 9:15 amTYS-FCO
17h 20m2 stops
United Airlines Logo
9:45 am - 8:33 pmFCO-TYS
16h 48m1 stop
$605United Airlines
Find Deal
Wed, Oct 22 - Thu, Nov 6
Logo
3:48 pm - 9:30 amTYS-FCO
12h 42m1 stop
Logo
12:40 pm - 11:46 pmFCO-TYS
17h 06m1 stop
$615
Find Deal
Sun, Oct 26 - Thu, Nov 6
Logo
9:50 am - 8:55 amTYS-FCO
17h 05m3 stops
Logo
1:15 pm - 10:48 amFCO-TYS
27h 33m2 stops
$617
Find Deal
Wed, Nov 12 - Fri, Nov 21
KLM Logo
3:43 pm - 7:55 amTYS-FCO
34h 12m1 stop
KLM Logo
12:40 pm - 11:46 pmFCO-TYS
17h 06m1 stop
$620KLM
Find Deal
Sat, Oct 25 - Thu, Nov 6
Delta Logo
3:43 pm - 7:55 amTYS-FCO
34h 12m1 stop
Delta Logo
12:00 pm - 11:04 amFCO-TYS
29h 04m2 stops
$625Delta
Find Deal
Sat, Oct 25 - Fri, Nov 7
Delta Logo
3:43 pm - 7:55 amTYS-FCO
34h 12m1 stop
Delta Logo
12:40 pm - 1:42 pmFCO-TYS
31h 02m1 stop
$626Delta
Find Deal
Sat, Oct 25 - Fri, Nov 7
Air Canada Logo
9:55 am - 8:55 amTYS-FCO
41h 00m2 stops
Air Canada Logo
1:15 pm - 11:59 pmFCO-TYS
16h 44m2 stops
$643Air Canada
Find Deal
Sat, Oct 25 - Wed, Nov 5
KLM Logo
3:43 pm - 7:55 amTYS-FCO
34h 12m1 stop
KLM Logo
12:40 pm - 11:46 pmFCO-TYS
17h 06m1 stop
$666KLM
Find Deal
Sat, Oct 25 - Fri, Nov 7
Air Canada Logo
9:55 am - 8:55 amTYS-FCO
41h 00m2 stops
Air Canada Logo
1:15 pm - 10:48 amFCO-TYS
27h 33m2 stops
$746Air Canada
Find Deal
Sat, Oct 25 - Fri, Nov 7

United Airlines flights from Knoxville to Rome

Our best United Airlines deals on Knoxville to Rome flight tickets
United Airlines
Nov 12
TYS8:26 amKnoxville McGhee Tyson
17h 19m
1 stop
FCO7:45 amRome Fiumicino
Nov 21
FCO1:15 pmRome Fiumicino
31h 28m
2 stops
TYS2:43 pmKnoxville McGhee Tyson
$582
Find similar
United Airlines
Oct 22
TYS9:55 amKnoxville McGhee Tyson
17h 20m
2 stops
FCO9:15 amRome Fiumicino
Nov 6
FCO9:45 amRome Fiumicino
16h 48m
1 stop
TYS8:33 pmKnoxville McGhee Tyson
$605
Find similar
United Airlines
Oct 22
TYS9:55 amKnoxville McGhee Tyson
17h 20m
2 stops
FCO9:15 amRome Fiumicino
Nov 5
FCO1:30 pmRome Fiumicino
16h 29m
2 stops
TYS11:59 pmKnoxville McGhee Tyson
$609
Find similar

KLM flights from Knoxville to Rome

Our best KLM deals on Knoxville to Rome flight tickets
KLM
Oct 25
TYS3:43 pmKnoxville McGhee Tyson
34h 12m
1 stop
FCO7:55 amRome Fiumicino
Nov 6
FCO12:40 pmRome Fiumicino
17h 06m
1 stop
TYS11:46 pmKnoxville McGhee Tyson
$620
Find similar
KLM
Oct 25
TYS3:43 pmKnoxville McGhee Tyson
34h 12m
1 stop
FCO7:55 amRome Fiumicino
Nov 7
FCO12:40 pmRome Fiumicino
17h 06m
1 stop
TYS11:46 pmKnoxville McGhee Tyson
$666
Find similar
KLM
Oct 23
TYS10:05 amKnoxville McGhee Tyson
15h 30m
1 stop
FCO7:35 amRome Fiumicino
Nov 7
FCO12:40 pmRome Fiumicino
17h 06m
1 stop
TYS11:46 pmKnoxville McGhee Tyson
$710
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Knoxville to Rome that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 21, 2025.
Use the filters below to find and compare flights from Knoxville to Rome that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

KnoxvilleRome

TYS - FCO

TYSFCO

Knoxville McGhee Tyson

Wed 11/12

8:26 am-7:45 am

1 stop17h 19m

Rome Fiumicino

Fri 11/21

1:15 pm-2:43 pm

2 stops31h 28m

$582

KnoxvilleRome

TYS - FCO

TYSFCO

Knoxville McGhee Tyson

Wed 10/22

9:55 am-9:15 am

2 stops17h 20m

Rome Fiumicino

Thu 11/6

9:45 am-8:33 pm

1 stop16h 48m

$605

KnoxvilleRome

TYS - FCO

TYSFCO

Knoxville McGhee Tyson

Sun 10/26

3:48 pm-9:30 am

1 stop12h 42m

Rome Fiumicino

Thu 11/6

12:40 pm-11:46 pm

1 stop17h 06m

$615

KnoxvilleRome

TYS - FCO

TYSFCO

Knoxville McGhee Tyson

Wed 11/12

9:50 am-8:55 am

3 stops17h 05m

Rome Fiumicino

Fri 11/21

1:15 pm-10:48 am

2 stops27h 33m

$617

KnoxvilleRome

TYS - FCO

TYSFCO

Knoxville McGhee Tyson

Sat 10/25

3:43 pm-7:55 am

1 stop34h 12m

Rome Fiumicino

Thu 11/6

12:40 pm-11:46 pm

1 stop17h 06m

$620

KnoxvilleRome

TYS - FCO

TYSFCO

Knoxville McGhee Tyson

Sat 10/25

3:43 pm-7:55 am

1 stop34h 12m

Rome Fiumicino

Fri 11/7

12:00 pm-11:04 am

2 stops29h 04m

$625

KnoxvilleRome

TYS - FCO

TYSFCO

Knoxville McGhee Tyson

Sat 10/25

3:43 pm-7:55 am

1 stop34h 12m

Rome Fiumicino

Fri 11/7

12:40 pm-1:42 pm

1 stop31h 02m

$626

KnoxvilleRome

TYS - FCO

TYSFCO

Knoxville McGhee Tyson

Sat 10/25

9:55 am-8:55 am

2 stops41h 00m

Rome Fiumicino

Wed 11/5

1:15 pm-11:59 pm

2 stops16h 44m

$643

KnoxvilleRome

TYS - FCO

TYSFCO

Knoxville McGhee Tyson

Sat 10/25

3:43 pm-7:55 am

1 stop34h 12m

Rome Fiumicino

Fri 11/7

12:40 pm-11:46 pm

1 stop17h 06m

$666

KnoxvilleRome

TYS - FCO

TYSFCO

Knoxville McGhee Tyson

Sat 10/25

9:55 am-8:55 am

2 stops41h 00m

Rome Fiumicino

Fri 11/7

1:15 pm-10:48 am

2 stops27h 33m

$746

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
1
2

See travel insights to Rome from

How to get the cheapest flight ticket from Knoxville to Rome

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Rome?

The cheapest month to fly to Rome from Knoxville is in January. Flight prices, which tend to average around $776, are often lower during this time because this is during the off-season. If you aren’t able to travel to Rome during the month of January, then flying in February is also cheap. Prices for this month can be found on momondo for an average of $790.

What is the cheapest day to depart on your flight to Rome?

The cheapest day to depart on your flight to Rome is on a Wednesday when prices can be found for as low as $1,088. This is often the case because there is less demand to fly during this day of the week. Be sure to avoid booking your departure on a Friday as prices are generally higher than usual. According to our data, the average ticket price to Rome on Friday is $1,292.

What is the cheapest time of day to depart on your flight to Rome?

In the afternoon is the cheapest time of day to fly from Knoxville to Rome when you can find flight prices for as low as $1,092. Flying to Rome in the afternoon is an ideal time because this is during off-peak travel hours. Flights to Rome are more costly at noon, with an average ticket price of $1,320. Departure times at noon fall within the peak daily travel times, which is why tickets can be more expensive.

Can stopping save me money on Knoxville to Rome flights?

You could potentially save up to 11% on your flight if you consider stops on a Knoxville to Rome flight.

When to book flights from Knoxville to Rome

Are you open to changing your travel dates? Check out the ideal times to fly from Knoxville to Rome according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Knoxville to Rome (TYS to ROM) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Knoxville to Rome

Direct flights

None
There are no direct flights from Knoxville to Rome. There are no popular flight routes from Knoxville to Rome.
Search flight deals

  • How far is Knoxville McGhee Tyson to Rome by plane?

    Knoxville McGhee Tyson and Rome are 4904.9 mi apart from one another. Flights usually cover this in 11h 08m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Knoxville McGhee Tyson Airport to Rome?

    Prices for flights from Knoxville McGhee Tyson Airport to Rome are updated daily.

  • How many operators does momondo search for flights from Knoxville McGhee Tyson Airport to Rome?

  • How old do you have to be to fly from Knoxville McGhee Tyson Airport to Rome?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Knoxville McGhee Tyson Airport to Rome.

  • What documentation or ID do you need to fly to Rome?

    The required travel and health documents for your Rome trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Rome. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Knoxville to Rome?

Best airlines flying from Knoxville to Rome

Compare and see reviews for airlines that fly from Knoxville to Rome with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $612Free CancellationRating
7.9
7,981 reviews
Search Delta flights
United AirlinesPriceFrom $702Free CancellationRating
7.4
8,930 reviews
Search United Airlines flights
American AirlinesPriceFrom $718Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights

Traveling to a place near Rome?

Book flights to Rome if you plan to visit one of these locations
Fiumicino
Civitavecchia
Cassino
Ponza
Pienza
Tivoli
Sperlonga
Ciampino
Gaeta
Santa Marinella
Cortona
Orvieto
Montepulciano
Saturnia
Grosseto
Anzio
Sabaudia
Terracina
Ascoli Piceno
Foligno

Why use momondo?

Why should I use momondo to find a flight deal from Knoxville to Rome?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Knoxville to Rome for you.

Can I find flights from Knoxville to Rome with flexible booking policies on momondo?

All flight searches from Knoxville to Rome on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Knoxville to Rome?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Rome from Knoxville.

I’m not ready to book a flight from Knoxville to Rome right now. Can momondo alert me if prices change?

Price alerts on flights to Rome from Knoxville are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

An easier way to manage your Rome trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
Start using Trips
Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.
1 adult
Tue 8/26
Tue 9/2
By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to Italy

Fly into one of these airports located in Rome

Airports listed have a maximum distance of 14.7 mi from Rome
Rome Ciampino Airport
Rome Fiumicino Airport