When did momondo last update prices for flights from Knoxville McGhee Tyson Airport to Panama?

Prices for flights from Knoxville McGhee Tyson Airport to Panama are updated daily.

How many operators does momondo search for flights from Knoxville McGhee Tyson Airport to Panama?

As of September 2026, there is 1 operator available to choose from for flights from Knoxville McGhee Tyson Airport to Panama.

How old do you have to be to fly from Knoxville McGhee Tyson Airport to Panama?

The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Knoxville McGhee Tyson Airport to Panama.

What documentation or ID do you need to fly to Panama?

The necessary travel and health documents for your Panama trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

$673 Cheap Flights from Knoxville to Panama in 2026/27

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Knoxville to Panama

Round-trip

Cheap round-trip flights

Enter your travel dates to find the best prices.

6:20 am - 8:02 pmTYS Knoxville McGhee Tyson-PTY Panama City Tocumen Intl

13h 42m1 stop Newark

8:55 am - 6:18 pmPTY Panama City Tocumen Intl-TYS Knoxville McGhee Tyson

9h 23m1 stop Houston George Bush Intcntl

$673United Airlines

Wed, Dec 9 - Wed, Dec 16

6:15 am - 8:02 pmTYS Knoxville McGhee Tyson-PTY Panama City Tocumen Intl

13h 47m1 stop Newark

8:55 am - 6:23 pmPTY Panama City Tocumen Intl-TYS Knoxville McGhee Tyson

9h 28m1 stop Houston George Bush Intcntl

$675United Airlines

Fri, Jan 15 - Tue, Jan 26

6:25 am - 7:38 pmTYS Knoxville McGhee Tyson-PTY Panama City Tocumen Intl

13h 13m2 stops Chicago O'Hare Intl Houston George Bush Intcntl

8:55 am - 11:59 pmPTY Panama City Tocumen Intl-TYS Knoxville McGhee Tyson

15h 04m2 stops Houston George Bush Intcntl Washington, D.C. Dulles Intl

$677United Airlines

Wed, Dec 9 - Wed, Dec 16

6:25 am - 7:38 pmTYS Knoxville McGhee Tyson-PTY Panama City Tocumen Intl

13h 13m2 stops Chicago O'Hare Intl Houston George Bush Intcntl

8:55 am - 6:18 pmPTY Panama City Tocumen Intl-TYS Knoxville McGhee Tyson

9h 23m1 stop Houston George Bush Intcntl

$677United Airlines

Wed, Dec 9 - Wed, Dec 16

7:00 am - 2:45 pmTYS Knoxville McGhee Tyson-PTY Panama City Tocumen Intl

7h 45m1 stop Houston George Bush Intcntl

4:41 pm - 11:12 amPTY Panama City Tocumen Intl-TYS Knoxville McGhee Tyson

18h 31m1 stop Houston George Bush Intcntl

$678United Airlines

Thu, Nov 5 - Thu, Nov 12

7:00 am - 2:45 pmTYS Knoxville McGhee Tyson-PTY Panama City Tocumen Intl

7h 45m1 stop Houston George Bush Intcntl

10:00 am - 9:53 amPTY Panama City Tocumen Intl-TYS Knoxville McGhee Tyson

23h 53m2 stops Newark Chicago O'Hare Intl

$682United Airlines

Thu, Nov 5 - Thu, Nov 12

3:55 pm - 2:13 pmTYS Knoxville McGhee Tyson-PTY Panama City Tocumen Intl

22h 18m2 stops Philadelphia Miami

3:13 pm - 10:30 amPTY Panama City Tocumen Intl-TYS Knoxville McGhee Tyson

19h 17m2 stops Miami Charlotte Douglas

$684American Airlines

Thu, Nov 5 - Thu, Nov 12

7:05 pm - 3:55 pmTYS Knoxville McGhee Tyson-PTY Panama City Tocumen Intl

20h 50m2 stops Dallas/Fort Worth Miami

2:25 pm - 11:50 amPTY Panama City Tocumen Intl-TYS Knoxville McGhee Tyson

21h 25m2 stops Miami Dallas/Fort Worth

$691American Airlines

Fri, Jan 15 - Tue, Jan 26

7:09 am - 12:59 pmTYS Knoxville McGhee Tyson-PTY Panama City Tocumen Intl

6h 50m1 stop Atlanta Hartsfield-Jackson

2:24 pm - 10:22 pmPTY Panama City Tocumen Intl-TYS Knoxville McGhee Tyson

6h 58m1 stop Atlanta Hartsfield-Jackson

$819Delta

Mon, Oct 12 - Tue, Oct 20

6:23 pm - 12:59 pmTYS Knoxville McGhee Tyson-PTY Panama City Tocumen Intl

19h 36m1 stop Atlanta Hartsfield-Jackson

2:24 pm - 10:22 pmPTY Panama City Tocumen Intl-TYS Knoxville McGhee Tyson

6h 58m1 stop Atlanta Hartsfield-Jackson

$826Delta

Sun, Oct 11 - Tue, Oct 20

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Delta flights from Knoxville to Panama

Our best Delta deals on Knoxville to Panama flight tickets

Delta

Oct 12

TYS7:09 amKnoxville McGhee Tyson

6h 50m

1 stop

PTY12:59 pmPanama City Tocumen Intl

Oct 20

PTY2:24 pmPanama City Tocumen Intl

6h 58m

1 stop

TYS10:22 pmKnoxville McGhee Tyson

$819

Delta

Oct 11

TYS6:23 pmKnoxville McGhee Tyson

19h 36m

1 stop

PTY12:59 pmPanama City Tocumen Intl

Oct 20

PTY2:24 pmPanama City Tocumen Intl

6h 58m

1 stop

TYS10:22 pmKnoxville McGhee Tyson

$826

Delta

Oct 11

TYS7:45 pmKnoxville McGhee Tyson

18h 14m

1 stop

PTY12:59 pmPanama City Tocumen Intl

Oct 19

PTY2:24 pmPanama City Tocumen Intl

8h 34m

1 stop

TYS11:58 pmKnoxville McGhee Tyson

$884

GOL flights from Knoxville to Panama

Our best GOL deals on Knoxville to Panama flight tickets

GOL

Oct 12

TYS7:58 pmKnoxville McGhee Tyson

18h 04m

2 stops

PTY1:02 pmPanama City Tocumen Intl

Oct 20

PTY2:02 pmPanama City Tocumen Intl

19h 21m

2 stops

TYS10:23 amKnoxville McGhee Tyson

$847

GOL

Oct 12

TYS7:58 pmKnoxville McGhee Tyson

18h 04m

2 stops

PTY1:02 pmPanama City Tocumen Intl

Oct 18

PTY2:02 pmPanama City Tocumen Intl

7h 57m

1 stop

TYS10:59 pmKnoxville McGhee Tyson

$889

GOL

Oct 13

TYS6:00 amKnoxville McGhee Tyson

8h 02m

1 stop

PTY1:02 pmPanama City Tocumen Intl

Oct 18

PTY2:02 pmPanama City Tocumen Intl

19h 23m

2 stops

TYS10:25 amKnoxville McGhee Tyson

$919

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

KnoxvillePanama City

TYS Knoxville McGhee Tyson - PTY Panama City Tocumen Intl

TYSPTY

Knoxville McGhee Tyson

Wed 12/9

6:20 am-8:02 pm

1 stop13h 42m

Panama City Tocumen Intl

Wed 12/16

8:55 am-6:18 pm

1 stop9h 23m

$673

KnoxvillePanama City

TYS Knoxville McGhee Tyson - PTY Panama City Tocumen Intl

TYSPTY

Knoxville McGhee Tyson

Fri 1/15

6:15 am-8:02 pm

1 stop13h 47m

Panama City Tocumen Intl

Tue 1/26

8:55 am-6:23 pm

1 stop9h 28m

$675

KnoxvillePanama City

TYS Knoxville McGhee Tyson - PTY Panama City Tocumen Intl

TYSPTY

Knoxville McGhee Tyson

Wed 12/9

6:25 am-7:38 pm

2 stops13h 13m

Panama City Tocumen Intl

Wed 12/16

8:55 am-11:59 pm

2 stops15h 04m

$677

KnoxvillePanama City

TYS Knoxville McGhee Tyson - PTY Panama City Tocumen Intl

TYSPTY

Knoxville McGhee Tyson

Wed 12/9

6:25 am-7:38 pm

2 stops13h 13m

Panama City Tocumen Intl

Wed 12/16

8:55 am-6:18 pm

1 stop9h 23m

$677

KnoxvillePanama City

TYS Knoxville McGhee Tyson - PTY Panama City Tocumen Intl

TYSPTY

Knoxville McGhee Tyson

Thu 11/5

7:00 am-2:45 pm

1 stop7h 45m

Panama City Tocumen Intl

Thu 11/12

4:41 pm-11:12 am

1 stop18h 31m

$678

KnoxvillePanama City

TYS Knoxville McGhee Tyson - PTY Panama City Tocumen Intl

TYSPTY

Knoxville McGhee Tyson

Thu 11/5

7:00 am-2:45 pm

1 stop7h 45m

Panama City Tocumen Intl

Thu 11/12

10:00 am-9:53 am

2 stops23h 53m

$682

KnoxvillePanama City

TYS Knoxville McGhee Tyson - PTY Panama City Tocumen Intl

TYSPTY

Knoxville McGhee Tyson

Thu 11/5

3:55 pm-2:13 pm

2 stops22h 18m

Panama City Tocumen Intl

Thu 11/12

3:13 pm-10:30 am

2 stops19h 17m

$684

KnoxvillePanama City

TYS Knoxville McGhee Tyson - PTY Panama City Tocumen Intl

TYSPTY

Knoxville McGhee Tyson

Fri 1/15

7:05 pm-3:55 pm

2 stops20h 50m

Panama City Tocumen Intl

Tue 1/26

2:25 pm-11:50 am

2 stops21h 25m

$691

Quickest round-trip

KnoxvillePanama City

TYS Knoxville McGhee Tyson - PTY Panama City Tocumen Intl

TYSPTY

Knoxville McGhee Tyson

Mon 10/12

7:09 am-12:59 pm

1 stop6h 50m

Panama City Tocumen Intl

Tue 10/20

2:24 pm-10:22 pm

1 stop6h 58m

$819

KnoxvillePanama City

TYS Knoxville McGhee Tyson - PTY Panama City Tocumen Intl

TYSPTY

Knoxville McGhee Tyson

Sun 10/11

6:23 pm-12:59 pm

1 stop19h 36m

Panama City Tocumen Intl

Tue 10/20

2:24 pm-10:22 pm

1 stop6h 58m

$826

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

How to get the cheapest flight ticket from Knoxville to Panama

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Panama?

The month of July is, on average, the cheapest month to fly to Panama from Knoxville, with most prices found around $0. If you don’t want to visit Panama in July, then you should wait until April to fly from Knoxville, when ticket prices are also cheap, with an average price of $496.

Cheap Knoxville to Panama flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Knoxville to Panama

Best Price Found	$673
Fastest flight time	7h 45m
Direct flights	None

The best flight deal from Knoxville to Panama found on momondo in the last 72 hours is $673

The fastest flight from Knoxville to Panama takes 7h 45m

There are no direct flights from Knoxville to Panama. There are no popular flight routes from Knoxville to Panama.

Search flight deals

Frequently asked questions about flying from Knoxville to Panama

When did momondo last update prices for flights from Knoxville McGhee Tyson Airport to Panama?
Prices for flights from Knoxville McGhee Tyson Airport to Panama are updated daily.
How many operators does momondo search for flights from Knoxville McGhee Tyson Airport to Panama?
As of September 2026, there is 1 operator available to choose from for flights from Knoxville McGhee Tyson Airport to Panama.
How old do you have to be to fly from Knoxville McGhee Tyson Airport to Panama?
The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Knoxville McGhee Tyson Airport to Panama.
What documentation or ID do you need to fly to Panama?
The necessary travel and health documents for your Panama trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Best airlines flying from Knoxville to Panama

Compare and see reviews for airlines that fly from Knoxville to Panama with momondo

Airline	Rating	Free Cancellation	Price
Delta	PriceFrom $547	Free Cancellation	Rating 7.8 8,591 reviews		Search Delta flights

Why use momondo?

Why should I use momondo to find a flight deal from Knoxville to Panama?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Knoxville to Panama. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Knoxville to Panama with flexible booking policies on momondo?

Yes. All flights to Panama from Knoxville on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Knoxville to Panama?

momondo helps you find the best flight between Knoxville and Panama by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Knoxville to Panama right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Knoxville to Panama now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Panama and let you know when they change.

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Flights to Panama Cityfrom $498

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Cheap flights from Knoxville to Panama from $673

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Knoxville to Panama departing on 12/9. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.

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Delta flights from Knoxville to Panama

Our best Delta deals on Knoxville to Panama flight tickets

GOL flights from Knoxville to Panama

Our best GOL deals on Knoxville to Panama flight tickets

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How to get the cheapest flight ticket from Knoxville to Panama

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Best Price Found

Fastest flight time

Direct flights

Frequently asked questions about flying from Knoxville to Panama

Best airlines flying from Knoxville to Panama

Compare and see reviews for airlines that fly from Knoxville to Panama with momondo

Why use momondo?

An easier way to manage your Panama trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

Find better results for your trip to Panama

Popular cities in Panama

Popular flights according to clicks in the last 7 days on momondo

Knoxville flight routes

According to popular flight searches on momondo this year

Panama flight routes

According to popular flight searches on momondo this year

Fly your favorite airline to Panama

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Cabin classes currently available on flights to Panama

List of cabin classes available on flights landing in Panama. Availability may vary depending on flight origin and airline.

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