When did momondo last update prices for flights from Knoxville McGhee Tyson Airport to Panama?

Prices for flights from Knoxville McGhee Tyson Airport to Panama are updated daily.

How old do you have to be to fly from Knoxville McGhee Tyson Airport to Panama?

The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Knoxville McGhee Tyson Airport to Panama.

What documentation or ID do you need to fly to Panama?

The necessary travel and health documents for your Panama trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

$734 Cheap Flights from Knoxville to Panama in 2026/27

Find the cheapest flights from Knoxville to Panama

Round-trip

Cheap round-trip flights

Enter your travel dates to find the best prices.

9:15 am - 6:37 pmTYS Knoxville McGhee Tyson-PTY Panama City Tocumen Intl

10h 22m1 stop Houston George Bush Intcntl

10:00 am - 11:19 pmPTY Panama City Tocumen Intl-TYS Knoxville McGhee Tyson

12h 19m1 stop Houston George Bush Intcntl

$734United Airlines

Wed, Apr 28 - Sat, May 1

9:15 am - 6:37 pmTYS Knoxville McGhee Tyson-PTY Panama City Tocumen Intl

10h 22m1 stop Houston George Bush Intcntl

7:55 am - 5:37 pmPTY Panama City Tocumen Intl-TYS Knoxville McGhee Tyson

8h 42m1 stop Houston George Bush Intcntl

$734United Airlines

Mon, Apr 19 - Fri, Apr 23

7:00 am - 2:14 pmTYS Knoxville McGhee Tyson-PTY Panama City Tocumen Intl

8h 14m1 stop Houston George Bush Intcntl

10:00 am - 10:00 amPTY Panama City Tocumen Intl-TYS Knoxville McGhee Tyson

23h 00m2 stops Houston George Bush Intcntl Washington, D.C. Dulles Intl

$739United Airlines

Wed, Apr 28 - Sat, May 1

10:50 am - 4:04 amTYS Knoxville McGhee Tyson-PTY Panama City Tocumen Intl

18h 14m2 stops Chicago O'Hare Intl Newark

7:55 am - 9:05 pmPTY Panama City Tocumen Intl-TYS Knoxville McGhee Tyson

12h 10m2 stops Houston George Bush Intcntl Chicago O'Hare Intl

$739United Airlines

Wed, Apr 28 - Sat, May 1

2:00 pm - 4:04 amTYS Knoxville McGhee Tyson-PTY Panama City Tocumen Intl

15h 04m2 stops Chicago O'Hare Intl Newark

10:55 pm - 1:18 pmPTY Panama City Tocumen Intl-TYS Knoxville McGhee Tyson

13h 23m2 stops Newark Chicago O'Hare Intl

$739United Airlines

Mon, Apr 19 - Fri, Apr 23

12:00 pm - 6:37 pmTYS Knoxville McGhee Tyson-PTY Panama City Tocumen Intl

7h 37m1 stop Houston George Bush Intcntl

10:55 pm - 4:49 pmPTY Panama City Tocumen Intl-TYS Knoxville McGhee Tyson

16h 54m2 stops Newark Chicago O'Hare Intl

$739United Airlines

Mon, Apr 19 - Fri, Apr 23

6:00 am - 2:34 pmTYS Knoxville McGhee Tyson-PTY Panama City Tocumen Intl

8h 34m1 stop Miami

3:34 pm - 11:21 amPTY Panama City Tocumen Intl-TYS Knoxville McGhee Tyson

19h 47m2 stops Miami Philadelphia

$1,020American Airlines

Fri, Nov 27 - Sun, Nov 29

3:47 pm - 2:34 pmTYS Knoxville McGhee Tyson-PTY Panama City Tocumen Intl

22h 47m2 stops Charlotte Douglas Miami

3:34 pm - 11:21 amPTY Panama City Tocumen Intl-TYS Knoxville McGhee Tyson

19h 47m2 stops Miami Philadelphia

$1,099American Airlines

Fri, Nov 27 - Sun, Nov 29

6:00 am - 2:34 pmTYS Knoxville McGhee Tyson-PTY Panama City Tocumen Intl

8h 34m1 stop Miami

3:34 pm - 12:52 amPTY Panama City Tocumen Intl-TYS Knoxville McGhee Tyson

9h 18m1 stop Miami

$1,115American Airlines

Fri, Nov 27 - Sun, Nov 29

6:47 pm - 3:33 pmTYS Knoxville McGhee Tyson-PTY Panama City Tocumen Intl

20h 46m1 stop Miami

2:41 pm - 10:58 pmPTY Panama City Tocumen Intl-TYS Knoxville McGhee Tyson

8h 17m1 stop Miami

$1,126American Airlines

Fri, Dec 18 - Fri, Dec 25

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American Airlines flights from Knoxville to Panama

Our best American Airlines deals on Knoxville to Panama flight tickets

American Airlines

Nov 27

TYS6:00 amKnoxville McGhee Tyson

8h 34m

1 stop

PTY2:34 pmPanama City Tocumen Intl

Nov 29

PTY3:34 pmPanama City Tocumen Intl

19h 47m

2 stops

TYS11:21 amKnoxville McGhee Tyson

$1,020

American Airlines

Nov 27

TYS3:47 pmKnoxville McGhee Tyson

22h 47m

2 stops

PTY2:34 pmPanama City Tocumen Intl

Nov 29

PTY3:34 pmPanama City Tocumen Intl

19h 47m

2 stops

TYS11:21 amKnoxville McGhee Tyson

$1,099

American Airlines

Nov 27

TYS6:00 amKnoxville McGhee Tyson

8h 34m

1 stop

PTY2:34 pmPanama City Tocumen Intl

Nov 29

PTY3:34 pmPanama City Tocumen Intl

9h 18m

1 stop

TYS12:52 amKnoxville McGhee Tyson

$1,115

United Airlines flights from Knoxville to Panama

Our best United Airlines deals on Knoxville to Panama flight tickets

United Airlines

Apr 28

TYS9:15 amKnoxville McGhee Tyson

10h 22m

1 stop

PTY6:37 pmPanama City Tocumen Intl

May 1

PTY10:00 amPanama City Tocumen Intl

12h 19m

1 stop

TYS11:19 pmKnoxville McGhee Tyson

$734

United Airlines

Apr 28

TYS7:00 amKnoxville McGhee Tyson

8h 14m

1 stop

PTY2:14 pmPanama City Tocumen Intl

May 1

PTY10:00 amPanama City Tocumen Intl

23h 00m

2 stops

TYS10:00 amKnoxville McGhee Tyson

$739

United Airlines

Nov 23

TYS6:45 amKnoxville McGhee Tyson

13h 17m

2 stops

PTY8:02 pmPanama City Tocumen Intl

Dec 7

PTY8:55 amPanama City Tocumen Intl

9h 23m

1 stop

TYS6:18 pmKnoxville McGhee Tyson

$863

Fly from

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Route

Depart

Return

Price

Cheapest round-trip

KnoxvillePanama City

TYS Knoxville McGhee Tyson - PTY Panama City Tocumen Intl

TYSPTY

Knoxville McGhee Tyson

Wed 4/28

9:15 am-6:37 pm

1 stop10h 22m

Panama City Tocumen Intl

Sat 5/1

10:00 am-11:19 pm

1 stop12h 19m

$734

KnoxvillePanama City

TYS Knoxville McGhee Tyson - PTY Panama City Tocumen Intl

TYSPTY

Knoxville McGhee Tyson

Mon 4/19

9:15 am-6:37 pm

1 stop10h 22m

Panama City Tocumen Intl

Fri 4/23

7:55 am-5:37 pm

1 stop8h 42m

$734

KnoxvillePanama City

TYS Knoxville McGhee Tyson - PTY Panama City Tocumen Intl

TYSPTY

Knoxville McGhee Tyson

Wed 4/28

7:00 am-2:14 pm

1 stop8h 14m

Panama City Tocumen Intl

Sat 5/1

10:00 am-10:00 am

2 stops23h 00m

$739

KnoxvillePanama City

TYS Knoxville McGhee Tyson - PTY Panama City Tocumen Intl

TYSPTY

Knoxville McGhee Tyson

Wed 4/28

10:50 am-4:04 am

2 stops18h 14m

Panama City Tocumen Intl

Sat 5/1

7:55 am-9:05 pm

2 stops12h 10m

$739

KnoxvillePanama City

TYS Knoxville McGhee Tyson - PTY Panama City Tocumen Intl

TYSPTY

Knoxville McGhee Tyson

Mon 4/19

2:00 pm-4:04 am

2 stops15h 04m

Panama City Tocumen Intl

Fri 4/23

10:55 pm-1:18 pm

2 stops13h 23m

$739

KnoxvillePanama City

TYS Knoxville McGhee Tyson - PTY Panama City Tocumen Intl

TYSPTY

Knoxville McGhee Tyson

Mon 4/19

12:00 pm-6:37 pm

1 stop7h 37m

Panama City Tocumen Intl

Fri 4/23

10:55 pm-4:49 pm

2 stops16h 54m

$739

KnoxvillePanama City

TYS Knoxville McGhee Tyson - PTY Panama City Tocumen Intl

TYSPTY

Knoxville McGhee Tyson

Fri 11/27

6:00 am-2:34 pm

1 stop8h 34m

Panama City Tocumen Intl

Sun 11/29

3:34 pm-11:21 am

2 stops19h 47m

$1,020

KnoxvillePanama City

TYS Knoxville McGhee Tyson - PTY Panama City Tocumen Intl

TYSPTY

Knoxville McGhee Tyson

Fri 11/27

3:47 pm-2:34 pm

2 stops22h 47m

Panama City Tocumen Intl

Sun 11/29

3:34 pm-11:21 am

2 stops19h 47m

$1,099

Quickest round-trip

KnoxvillePanama City

TYS Knoxville McGhee Tyson - PTY Panama City Tocumen Intl

TYSPTY

Knoxville McGhee Tyson

Fri 11/27

6:00 am-2:34 pm

1 stop8h 34m

Panama City Tocumen Intl

Sun 11/29

3:34 pm-12:52 am

1 stop9h 18m

$1,115

KnoxvillePanama City

TYS Knoxville McGhee Tyson - PTY Panama City Tocumen Intl

TYSPTY

Knoxville McGhee Tyson

Fri 12/18

6:47 pm-3:33 pm

1 stop20h 46m

Panama City Tocumen Intl

Fri 12/25

2:41 pm-10:58 pm

1 stop8h 17m

$1,126

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

How to get the cheapest flight ticket from Knoxville to Panama

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Panama?

The month of July is, on average, the cheapest month to fly to Panama from Knoxville, with most prices found around $0. If you don’t want to visit Panama in July, then you should wait until April to fly from Knoxville, when ticket prices are also cheap, with an average price of $496.

Cheap Knoxville to Panama flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Knoxville to Panama

Best Price Found	$734
Fastest flight time	7h 45m
Direct flights	None

The best flight deal from Knoxville to Panama found on momondo in the last 72 hours is $734

The fastest flight from Knoxville to Panama takes 7h 45m

There are no direct flights from Knoxville to Panama. There are no popular flight routes from Knoxville to Panama.

Search flight deals

Frequently asked questions about flying from Knoxville to Panama

When did momondo last update prices for flights from Knoxville McGhee Tyson Airport to Panama?
Prices for flights from Knoxville McGhee Tyson Airport to Panama are updated daily.
How old do you have to be to fly from Knoxville McGhee Tyson Airport to Panama?
The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Knoxville McGhee Tyson Airport to Panama.
What documentation or ID do you need to fly to Panama?
The necessary travel and health documents for your Panama trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Why use momondo?

Why should I use momondo to find a flight deal from Knoxville to Panama?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Knoxville to Panama. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Knoxville to Panama with flexible booking policies on momondo?

Yes. All flights to Panama from Knoxville on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Knoxville to Panama?

momondo helps you find the best flight between Knoxville and Panama by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Knoxville to Panama right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Knoxville to Panama now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Panama and let you know when they change.

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Cheap flights from Knoxville to Panama from $734

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Knoxville to Panama departing on 4/28. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.

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American Airlines flights from Knoxville to Panama

Our best American Airlines deals on Knoxville to Panama flight tickets

United Airlines flights from Knoxville to Panama

Our best United Airlines deals on Knoxville to Panama flight tickets

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How to get the cheapest flight ticket from Knoxville to Panama

What is the cheapest month to fly to Panama?

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Best Price Found

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Direct flights

Frequently asked questions about flying from Knoxville to Panama

Why use momondo?

An easier way to manage your Panama trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

Find better results for your trip to Panama

Popular cities in Panama

Popular flights according to clicks in the last 7 days on momondo

Knoxville flight routes

According to popular flight searches on momondo this year

Panama flight routes

According to popular flight searches on momondo this year

Fly your favorite airline to Panama

Airlines are sorted and displayed according to clicks in the past 7 days on momondo

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List of cabin classes available on flights landing in Panama. Availability may vary depending on flight origin and airline.

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According to popular flight searches on momondo this year