Cheap flights from Knoxville to Mexico City from $212

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Knoxville to Mexico City departing on 3/20. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Knoxville to Mexico City

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
4:47 pm - 10:00 pm
TYS
-
MEX
30h 13m2 stops
Multiple Airlines Logo
7:00 am - 8:39 am
MEX
-
TYS
24h 39m2 stops
$450Multiple Airlines
mié., ene. 28 - mié., feb. 4
Multiple Airlines Logo
4:47 pm - 10:00 pm
TYS
-
MEX
30h 13m2 stops
Multiple Airlines Logo
10:20 pm - 5:28 pm
MEX
-
TYS
18h 08m2 stops
$464Multiple Airlines
mié., ene. 21 - dom., ene. 25
Multiple Airlines Logo
4:47 pm - 10:00 pm
TYS
-
MEX
30h 13m2 stops
Multiple Airlines Logo
7:00 am - 5:28 pm
MEX
-
TYS
33h 28m3 stops
$467Multiple Airlines
mié., ene. 21 - dom., ene. 25
Multiple Airlines Logo
4:47 pm - 10:00 pm
TYS
-
MEX
30h 13m2 stops
Multiple Airlines Logo
7:00 am - 8:39 am
MEX
-
TYS
24h 39m3 stops
$468Multiple Airlines
mié., ene. 28 - mié., feb. 4
Multiple Airlines Logo
4:47 pm - 11:35 pm
TYS
-
MEX
31h 48m3 stops
Multiple Airlines Logo
7:00 am - 5:28 pm
MEX
-
TYS
33h 28m3 stops
$486Multiple Airlines
mié., ene. 21 - dom., ene. 25
Multiple Airlines Logo
4:47 pm - 10:00 pm
TYS
-
MEX
30h 13m3 stops
Multiple Airlines Logo
7:00 am - 8:39 am
MEX
-
TYS
24h 39m3 stops
$494Multiple Airlines
mié., ene. 28 - mié., feb. 4
Multiple Airlines Logo
9:29 am - 11:35 pm
TYS
-
MEX
39h 06m3 stops
Multiple Airlines Logo
10:20 pm - 5:28 pm
MEX
-
TYS
18h 08m2 stops
$514Multiple Airlines
jue., ene. 22 - dom., ene. 25
Multiple Airlines Logo
9:29 am - 11:35 pm
TYS
-
MEX
39h 06m3 stops
Multiple Airlines Logo
7:00 am - 5:28 pm
MEX
-
TYS
33h 28m3 stops
$517Multiple Airlines
jue., ene. 22 - dom., ene. 25
Multiple Airlines Logo
12:55 pm - 10:30 pm
TYS
-
MEX
10h 35m2 stops
Multiple Airlines Logo
7:00 am - 12:04 pm
MEX
-
TYS
28h 04m2 stops
$518Multiple Airlines
vie., feb. 6 - sáb., feb. 14
Aeromexico Logo
5:40 am - 11:20 am
TYS
-
MEX
6h 40m1 stop
Aeromexico Logo
2:10 pm - 11:45 pm
MEX
-
TYS
8h 35m1 stop
$523Aeromexico
mié., ene. 28 - mié., feb. 4

Aeromexico flights from Knoxville to Mexico City

Our best Aeromexico deals on Knoxville to Mexico City flight tickets
Aeromexico
Jan 28
TYS5:40 amKnoxville McGhee Tyson
6h 40m
1 stop
MEX11:20 amMexico City Benito Juarez
Feb 4
MEX2:10 pmMexico City Benito Juarez
8h 35m
1 stop
TYS11:45 pmKnoxville McGhee Tyson
Aeromexico
May 12
TYS5:30 amKnoxville McGhee Tyson
10h 25m
1 stop
MEX1:55 pmMexico City Benito Juarez
May 18
MEX7:05 amMexico City Benito Juarez
14h 41m
1 stop
TYS11:46 pmKnoxville McGhee Tyson
Aeromexico
Jan 19
TYS5:40 amKnoxville McGhee Tyson
8h 15m
1 stop
MEX12:55 pmMexico City Benito Juarez
Jan 22
MEX8:40 amMexico City Benito Juarez
5h 39m
1 stop
TYS3:19 pmKnoxville McGhee Tyson

American Airlines flights from Knoxville to Mexico City

Our best American Airlines deals on Knoxville to Mexico City flight tickets
American Airlines
Feb 6
TYS11:19 amKnoxville McGhee Tyson
11h 36m
2 stops
MEX9:55 pmMexico City Benito Juarez
Feb 14
MEX11:20 amMexico City Benito Juarez
9h 40m
1 stop
TYS10:00 pmKnoxville McGhee Tyson
American Airlines
Mar 8
TYS5:00 amKnoxville McGhee Tyson
8h 45m
1 stop
MEX11:45 amMexico City Benito Juarez
Mar 11
MEX5:00 amMexico City Benito Juarez
10h 31m
1 stop
TYS5:31 pmKnoxville McGhee Tyson
American Airlines
Mar 7
TYS6:00 amKnoxville McGhee Tyson
10h 15m
2 stops
MEX3:15 pmMexico City Benito Juarez
Mar 12
MEX7:00 amMexico City Benito Juarez
6h 31m
1 stop
TYS3:31 pmKnoxville McGhee Tyson

momondo Fare Finder

 
Customize your flight search to find flights from Knoxville to Mexico City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated diciembre 15, 2025.
Use the filters below to find and compare flights from Knoxville to Mexico City that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

KnoxvilleMexico City

TYS - MEX

TYSMEX

Knoxville McGhee Tyson

mié. 1/28

4:47 pm-10:00 pm

2 stops30h 13m

Mexico City Benito Juarez

mié. 2/4

7:00 am-8:39 am

2 stops24h 39m

$450

KnoxvilleMexico City

TYS - MEX

TYSMEX

Knoxville McGhee Tyson

mié. 1/21

4:47 pm-10:00 pm

2 stops30h 13m

Mexico City Benito Juarez

dom. 1/25

10:20 pm-5:28 pm

2 stops18h 08m

$464

KnoxvilleMexico City

TYS - MEX

TYSMEX

Knoxville McGhee Tyson

mié. 1/21

4:47 pm-10:00 pm

2 stops30h 13m

Mexico City Benito Juarez

dom. 1/25

7:00 am-5:28 pm

3 stops33h 28m

$467

KnoxvilleMexico City

TYS - MEX

TYSMEX

Knoxville McGhee Tyson

mié. 1/28

4:47 pm-10:00 pm

2 stops30h 13m

Mexico City Benito Juarez

mié. 2/4

7:00 am-8:39 am

3 stops24h 39m

$468

KnoxvilleMexico City

TYS - MEX

TYSMEX

Knoxville McGhee Tyson

mié. 1/21

4:47 pm-11:35 pm

3 stops31h 48m

Mexico City Benito Juarez

dom. 1/25

7:00 am-5:28 pm

3 stops33h 28m

$486

KnoxvilleMexico City

TYS - MEX

TYSMEX

Knoxville McGhee Tyson

mié. 1/28

4:47 pm-10:00 pm

3 stops30h 13m

Mexico City Benito Juarez

mié. 2/4

7:00 am-8:39 am

3 stops24h 39m

$494

KnoxvilleMexico City

TYS - MEX

TYSMEX

Knoxville McGhee Tyson

jue. 1/22

9:29 am-11:35 pm

3 stops39h 06m

Mexico City Benito Juarez

dom. 1/25

10:20 pm-5:28 pm

2 stops18h 08m

$514

KnoxvilleMexico City

TYS - MEX

TYSMEX

Knoxville McGhee Tyson

jue. 1/22

9:29 am-11:35 pm

3 stops39h 06m

Mexico City Benito Juarez

dom. 1/25

7:00 am-5:28 pm

3 stops33h 28m

$517

KnoxvilleMexico City

TYS - MEX

TYSMEX

Knoxville McGhee Tyson

vie. 2/6

12:55 pm-10:30 pm

2 stops10h 35m

Mexico City Benito Juarez

sáb. 2/14

7:00 am-12:04 pm

2 stops28h 04m

$518

KnoxvilleMexico City

TYS - MEX

TYSMEX

Knoxville McGhee Tyson

mié. 1/28

5:40 am-11:20 am

1 stop6h 40m

Mexico City Benito Juarez

mié. 2/4

2:10 pm-11:45 pm

1 stop8h 35m

$523

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Mexico City from

How to get the cheapest flight ticket from Knoxville to Mexico City

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Mexico City?

The cheapest month to fly to Mexico City from Knoxville is in April. Flight prices, which tend to average around $487, are often lower during this time because this is during the off-season. If you aren’t able to travel during the month of April, then book flights to Mexico City from Knoxville during August instead. Flights to Mexico City in August, while not as cheap as those in April, still average around $546.

What is the cheapest day to depart on your flight to Mexico City?

Our data shows that Wednesday is the least expensive day to fly to Mexico City. Tickets to fly out on this day can be as low as $657. On the other hand, Monday is the most expensive day to depart from Knoxville because it is more convenient for both business and leisure travelers. As a result, prices tend to be around $798.

What is the cheapest time of day to depart on your flight to Mexico City?

According to our data, the cheapest time of day to fly to Mexico City is at noon. momondo users have found flights departing from Knoxville to Mexico City at noon for as low as $678. Keep in mind that these prices may fluctuate based on what airline you choose and the time of year you plan to travel. In the afternoon is when there is more demand to fly to Mexico City, so prices are often more expensive at around $884 per ticket.

When to book flights from Knoxville to Mexico City

Are you open to changing your travel dates? Check out the ideal times to fly from Knoxville to Mexico City according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Knoxville to Mexico City (TYS to MEX) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Knoxville to Mexico City

Fastest flight time

10h 20m

Direct flights

None
The fastest flight from Knoxville to Mexico City takes 10h 20m
There are no direct flights from Knoxville to Mexico City. There are no popular flight routes from Knoxville to Mexico City.
  • How far is Knoxville McGhee Tyson to Mexico City Benito Juarez by plane?

    Knoxville McGhee Tyson and Mexico City Benito Juarez are 1469.6 mi apart from one another. A reasonable flight in good conditions will take 10h 20m.

  • When did momondo last update prices for flights from Knoxville McGhee Tyson Airport to Mexico City Benito Juarez Airport?

    Prices for flights from Knoxville McGhee Tyson Airport to Mexico City Benito Juarez Airport were last updated today.

  • How many operators does momondo search for flights from Knoxville McGhee Tyson Airport to Mexico City Benito Juarez Airport?

  • How old do you have to be to fly from Knoxville McGhee Tyson Airport to Mexico City Benito Juarez Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Knoxville McGhee Tyson Airport to Mexico City Benito Juarez Airport.

  • What documentation or ID do you need to fly to Mexico City Benito Juarez Airport?

    The travel and health documents you'll need for your trip to Mexico City Benito Juarez Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Mexico City Benito Juarez Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Knoxville to Mexico City?

Best airlines flying from Knoxville to Mexico City

Compare and see reviews for airlines that fly from Knoxville to Mexico City with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $318Free CancellationRating
7.9
8,007 reviews
Search Delta flights
American AirlinesPriceFrom $455Free CancellationRating
7.2
11,052 reviews
Search American Airlines flights

Traveling to a place near Mexico City?

Book flights to Mexico City if you plan to visit one of these locations
Cuernavaca
Tepoztlán
Taxco
Valle de Bravo

Why use momondo?

Why should I use momondo to find a flight deal from Knoxville to Mexico City?

Finding the right flight to Mexico City from Knoxville is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Mexico City quick and easy, saving you time and money.

Can I find flights from Knoxville to Mexico City with flexible booking policies on momondo?

momondo does allow users to show only those flights to Mexico City from Knoxville which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Knoxville to Mexico City?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Mexico City from Knoxville.

I’m not ready to book a flight from Knoxville to Mexico City right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Mexico City from Knoxville. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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1 adult
mié. 1/14
mié. 1/21

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