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Cheap flights from Knoxville to Guatemala from $343

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Knoxville to Guatemala departing on 5/29. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Knoxville to Guatemala

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
7:30 am - 1:24 pm
TYS
-
GUA
7h 54m
1 stop
American Airlines Logo
12:04 pm - 11:18 pm
GUA
-
TYS
9h 14m
1 stop
$625American Airlines
Wed, Sep 9 - Wed, Sep 16
American Airlines Logo
10:50 am - 6:20 pm
TYS
-
GUA
9h 30m
2 stops
American Airlines Logo
1:15 pm - 11:31 pm
GUA
-
TYS
8h 16m
1 stop
$629American Airlines
Wed, Sep 9 - Wed, Sep 16
Multiple Airlines Logo
9:15 am - 6:35 pm
TYS
-
GUA
11h 20m
2 stops
Multiple Airlines Logo
7:10 pm - 2:42 pm
GUA
-
TYS
18h 32m
1 stop
$637Multiple Airlines
Wed, Oct 28 - Tue, Nov 3
American Airlines Logo
6:00 am - 1:24 pm
TYS
-
GUA
9h 24m
1 stop
American Airlines Logo
7:00 am - 4:37 pm
GUA
-
TYS
8h 37m
1 stop
$653American Airlines
Wed, Oct 28 - Tue, Nov 3
American Airlines Logo
7:13 am - 6:15 pm
TYS
-
GUA
13h 02m
2 stops
American Airlines Logo
11:37 am - 11:51 pm
GUA
-
TYS
11h 14m
2 stops
$657American Airlines
Wed, Oct 28 - Tue, Nov 3
Delta Logo
7:00 am - 12:30 pm
TYS
-
GUA
6h 30m
1 stop
Delta Logo
2:10 pm - 11:46 pm
GUA
-
TYS
8h 36m
1 stop
$663Delta
Sun, Nov 8 - Thu, Nov 12
Delta Logo
7:00 am - 12:30 pm
TYS
-
GUA
6h 30m
1 stop
Delta Logo
2:10 pm - 11:46 pm
GUA
-
TYS
8h 36m
1 stop
$683Delta
Sun, Nov 8 - Thu, Nov 12
American Airlines Logo
7:38 am - 8:14 pm
TYS
-
GUA
13h 36m
2 stops
American Airlines Logo
7:00 am - 9:31 pm
GUA
-
TYS
13h 31m
2 stops
$687American Airlines
Sun, Nov 8 - Thu, Nov 12
American Airlines Logo
5:40 am - 11:00 am
TYS
-
GUA
7h 20m
1 stop
American Airlines Logo
12:04 pm - 11:18 pm
GUA
-
TYS
9h 14m
1 stop
$703American Airlines
Fri, Sep 18 - Sat, Sep 19
American Airlines Logo
5:40 am - 11:00 am
TYS
-
GUA
7h 20m
1 stop
American Airlines Logo
12:04 pm - 8:25 am
GUA
-
TYS
18h 21m
2 stops
$707American Airlines
Fri, Sep 18 - Sat, Sep 19

United Airlines flights from Knoxville to Guatemala

Our best United Airlines deals on Knoxville to Guatemala flight tickets
United Airlines
May 27
TYS12:10 pmKnoxville McGhee Tyson
6h 27m
1 stop
GUA4:37 pmGuatemala City La Aurora
Jun 2
GUA11:55 pmGuatemala City La Aurora
8h 47m
1 stop
TYS10:42 amKnoxville McGhee Tyson
$755
United Airlines
Aug 24
TYS7:15 amKnoxville McGhee Tyson
11h 22m
1 stop
GUA4:37 pmGuatemala City La Aurora
Aug 26
GUA1:30 amGuatemala City La Aurora
20h 29m
2 stops
TYS11:59 pmKnoxville McGhee Tyson
$777
United Airlines
May 27
TYS12:10 pmKnoxville McGhee Tyson
6h 27m
1 stop
GUA4:37 pmGuatemala City La Aurora
Jun 2
GUA10:50 pmGuatemala City La Aurora
12h 28m
2 stops
TYS1:18 pmKnoxville McGhee Tyson
$780

American Airlines flights from Knoxville to Guatemala

Our best American Airlines deals on Knoxville to Guatemala flight tickets
American Airlines
Sep 9
TYS7:30 amKnoxville McGhee Tyson
7h 54m
1 stop
GUA1:24 pmGuatemala City La Aurora
Sep 16
GUA12:04 pmGuatemala City La Aurora
9h 14m
1 stop
TYS11:18 pmKnoxville McGhee Tyson
$625
American Airlines
Sep 9
TYS10:50 amKnoxville McGhee Tyson
9h 30m
2 stops
GUA6:20 pmGuatemala City La Aurora
Sep 16
GUA1:15 pmGuatemala City La Aurora
8h 16m
1 stop
TYS11:31 pmKnoxville McGhee Tyson
$629
American Airlines
Oct 28
TYS6:00 amKnoxville McGhee Tyson
9h 24m
1 stop
GUA1:24 pmGuatemala City La Aurora
Nov 3
GUA7:00 amGuatemala City La Aurora
8h 37m
1 stop
TYS4:37 pmKnoxville McGhee Tyson
$653

momondo Fare Finder

 
Customize your flight search to find flights from Knoxville to Guatemala that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated May 24, 2026.
Use the filters below to find and compare flights from Knoxville to Guatemala that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

KnoxvilleGuatemala City

TYS - GUA

TYSGUA

Knoxville McGhee Tyson

Wed 9/9

7:30 am-1:24 pm

1 stop7h 54m

Guatemala City La Aurora

Wed 9/16

12:04 pm-11:18 pm

1 stop9h 14m

$625

KnoxvilleGuatemala City

TYS - GUA

TYSGUA

Knoxville McGhee Tyson

Wed 9/9

10:50 am-6:20 pm

2 stops9h 30m

Guatemala City La Aurora

Wed 9/16

1:15 pm-11:31 pm

1 stop8h 16m

$629

KnoxvilleGuatemala City

TYS - GUA

TYSGUA

Knoxville McGhee Tyson

Wed 10/28

9:15 am-6:35 pm

2 stops11h 20m

Guatemala City La Aurora

Tue 11/3

7:10 pm-2:42 pm

1 stop18h 32m

$637

KnoxvilleGuatemala City

TYS - GUA

TYSGUA

Knoxville McGhee Tyson

Wed 10/28

6:00 am-1:24 pm

1 stop9h 24m

Guatemala City La Aurora

Tue 11/3

7:00 am-4:37 pm

1 stop8h 37m

$653

KnoxvilleGuatemala City

TYS - GUA

TYSGUA

Knoxville McGhee Tyson

Wed 10/28

7:13 am-6:15 pm

2 stops13h 02m

Guatemala City La Aurora

Tue 11/3

11:37 am-11:51 pm

2 stops11h 14m

$657
Quickest round-trip

KnoxvilleGuatemala City

TYS - GUA

TYSGUA

Knoxville McGhee Tyson

Sun 11/8

7:00 am-12:30 pm

1 stop6h 30m

Guatemala City La Aurora

Thu 11/12

2:10 pm-11:46 pm

1 stop8h 36m

$663

KnoxvilleGuatemala City

TYS - GUA

TYSGUA

Knoxville McGhee Tyson

Sun 11/8

7:00 am-12:30 pm

1 stop6h 30m

Guatemala City La Aurora

Thu 11/12

2:10 pm-11:46 pm

1 stop8h 36m

$683

KnoxvilleGuatemala City

TYS - GUA

TYSGUA

Knoxville McGhee Tyson

Sun 11/8

7:38 am-8:14 pm

2 stops13h 36m

Guatemala City La Aurora

Thu 11/12

7:00 am-9:31 pm

2 stops13h 31m

$687

KnoxvilleGuatemala City

TYS - GUA

TYSGUA

Knoxville McGhee Tyson

Fri 9/18

5:40 am-11:00 am

1 stop7h 20m

Guatemala City La Aurora

Sat 9/19

12:04 pm-11:18 pm

1 stop9h 14m

$703

KnoxvilleGuatemala City

TYS - GUA

TYSGUA

Knoxville McGhee Tyson

Fri 9/18

5:40 am-11:00 am

1 stop7h 20m

Guatemala City La Aurora

Sat 9/19

12:04 pm-8:25 am

2 stops18h 21m

$707

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 16 resultsSorted by cheapest first
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See travel insights to Guatemala from

How to get the cheapest flight ticket from Knoxville to Guatemala

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest airline that flies from Knoxville McGhee Tyson to Guatemala?

GOL and United Airlines are the most popular carriers operating from Knoxville McGhee Tyson to Guatemala

Cheap Knoxville to Guatemala flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Knoxville to Guatemala

Fastest flight time

6h 27m

Direct flights

None
The fastest flight from Knoxville to Guatemala takes 6h 27m
There are no direct flights from Knoxville to Guatemala. There are no popular flight routes from Knoxville to Guatemala.
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Frequently asked questions about flying from Knoxville to Guatemala

  • When did momondo last update prices for flights from Knoxville McGhee Tyson Airport to Guatemala?

    Prices for flights from Knoxville McGhee Tyson Airport to Guatemala are refreshed on a daily basis.

  • How many operators does momondo search for flights from Knoxville McGhee Tyson Airport to Guatemala?

  • How old do you have to be to fly from Knoxville McGhee Tyson Airport to Guatemala?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Knoxville McGhee Tyson Airport to Guatemala.

  • What documentation or ID do you need to fly to Guatemala?

    The travel and health documents required for your trip to Guatemala can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Guatemala. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Best airlines flying from Knoxville to Guatemala

Compare and see reviews for airlines that fly from Knoxville to Guatemala with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $509Free CancellationRating
7.1
11,631 reviews
Search American Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Knoxville to Guatemala?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Knoxville to Guatemala. momondo saves you time and could save you money on your trip.

Can I find flights from Knoxville to Guatemala with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Guatemala from Knoxville with this policy.

How can momondo help me find flights from Knoxville to Guatemala?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Knoxville to Guatemala.

I’m not ready to book a flight from Knoxville to Guatemala right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Guatemala, momondo offers a useful price alert feature which will track prices for flights to Guatemala from Knoxville and alert you when they change.

An easier way to manage your Guatemala trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
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