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Cheap flights from Knoxville to Guatemala from $343

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Knoxville to Guatemala departing on 11/28. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Knoxville to Guatemala

Cheap round-trip flights

Logo
7:25 pm - 4:50 amTYS-GUA
11h 25m1 stop
Logo
7:05 pm - 10:29 amGUA-TYS
13h 24m1 stop
$403
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Sat, Sep 13 - Sat, Oct 4
Logo
9:30 am - 6:35 pmTYS-GUA
11h 05m2 stops
Logo
7:05 pm - 10:29 amGUA-TYS
13h 24m1 stop
$538
Find Deal
Sat, Sep 13 - Sat, Oct 4
Logo
9:30 am - 6:35 pmTYS-GUA
11h 05m2 stops
Logo
7:05 pm - 10:29 amGUA-TYS
13h 24m1 stop
$568
Find Deal
Sat, Sep 13 - Sat, Oct 4
American Airlines Logo
11:07 am - 7:12 pmTYS-GUA
10h 05m2 stops
American Airlines Logo
6:30 am - 11:03 pmGUA-TYS
14h 33m2 stops
$612American Airlines
Find Deal
Sat, Sep 13 - Sat, Oct 4
American Airlines Logo
7:28 am - 5:14 pmTYS-GUA
11h 46m1 stop
American Airlines Logo
12:30 pm - 11:50 pmGUA-TYS
9h 20m1 stop
$652American Airlines
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Mon, Sep 8 - Sat, Oct 4
American Airlines Logo
5:05 am - 7:12 pmTYS-GUA
16h 07m2 stops
American Airlines Logo
12:30 pm - 11:50 pmGUA-TYS
9h 20m1 stop
$656American Airlines
Find Deal
Mon, Sep 8 - Sat, Oct 4
American Airlines Logo
7:29 am - 7:12 pmTYS-GUA
13h 43m2 stops
American Airlines Logo
8:30 am - 8:50 pmGUA-TYS
10h 20m2 stops
$659American Airlines
Find Deal
Sat, Sep 13 - Sat, Oct 4
United Airlines Logo
9:30 am - 4:32 pmTYS-GUA
9h 02m1 stop
United Airlines Logo
1:30 am - 7:52 pmGUA-TYS
16h 22m1 stop
$697United Airlines
Find Deal
Sat, Sep 13 - Fri, Oct 3
United Airlines Logo
12:00 pm - 4:32 pmTYS-GUA
6h 32m1 stop
United Airlines Logo
1:30 am - 6:10 pmGUA-TYS
14h 40m1 stop
$720United Airlines
Find Deal
Mon, Sep 8 - Fri, Oct 3
United Airlines Logo
9:30 am - 4:32 pmTYS-GUA
9h 02m1 stop
United Airlines Logo
1:30 am - 6:10 pmGUA-TYS
14h 40m1 stop
$740United Airlines
Find Deal
Sat, Sep 13 - Fri, Oct 3

American Airlines flights from Knoxville to Guatemala

Our best American Airlines deals on Knoxville to Guatemala flight tickets
American Airlines
Sep 13
TYS11:07 amKnoxville McGhee Tyson
10h 05m
2 stops
GUA7:12 pmGuatemala City La Aurora
Oct 4
GUA6:30 amGuatemala City La Aurora
14h 33m
2 stops
TYS11:03 pmKnoxville McGhee Tyson
$612
Find similar
American Airlines
Sep 8
TYS7:28 amKnoxville McGhee Tyson
11h 46m
1 stop
GUA5:14 pmGuatemala City La Aurora
Oct 4
GUA12:30 pmGuatemala City La Aurora
9h 20m
1 stop
TYS11:50 pmKnoxville McGhee Tyson
$652
Find similar
American Airlines
Sep 8
TYS5:05 amKnoxville McGhee Tyson
16h 07m
2 stops
GUA7:12 pmGuatemala City La Aurora
Oct 4
GUA12:30 pmGuatemala City La Aurora
9h 20m
1 stop
TYS11:50 pmKnoxville McGhee Tyson
$656
Find similar

United Airlines flights from Knoxville to Guatemala

Our best United Airlines deals on Knoxville to Guatemala flight tickets
United Airlines
Sep 13
TYS9:30 amKnoxville McGhee Tyson
9h 02m
1 stop
GUA4:32 pmGuatemala City La Aurora
Oct 3
GUA1:30 amGuatemala City La Aurora
16h 22m
1 stop
TYS7:52 pmKnoxville McGhee Tyson
$697
Find similar
United Airlines
Sep 8
TYS12:00 pmKnoxville McGhee Tyson
6h 32m
1 stop
GUA4:32 pmGuatemala City La Aurora
Oct 3
GUA1:30 amGuatemala City La Aurora
14h 40m
1 stop
TYS6:10 pmKnoxville McGhee Tyson
$720
Find similar
United Airlines
Sep 13
TYS9:30 amKnoxville McGhee Tyson
9h 02m
1 stop
GUA4:32 pmGuatemala City La Aurora
Oct 3
GUA1:30 amGuatemala City La Aurora
14h 40m
1 stop
TYS6:10 pmKnoxville McGhee Tyson
$740
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Knoxville to Guatemala that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 24, 2025.
Use the filters below to find and compare flights from Knoxville to Guatemala that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

KnoxvilleGuatemala City

TYS - GUA

TYSGUA

Knoxville McGhee Tyson

Sat 9/13

7:25 pm-4:50 am

1 stop11h 25m

Guatemala City La Aurora

Sat 10/4

7:05 pm-10:29 am

1 stop13h 24m

$403

KnoxvilleGuatemala City

TYS - GUA

TYSGUA

Knoxville McGhee Tyson

Sat 9/13

9:30 am-6:35 pm

2 stops11h 05m

Guatemala City La Aurora

Sat 10/4

7:05 pm-10:29 am

1 stop13h 24m

$538

KnoxvilleGuatemala City

TYS - GUA

TYSGUA

Knoxville McGhee Tyson

Sat 9/13

9:30 am-6:35 pm

2 stops11h 05m

Guatemala City La Aurora

Sat 10/4

7:05 pm-10:29 am

1 stop13h 24m

$568

KnoxvilleGuatemala City

TYS - GUA

TYSGUA

Knoxville McGhee Tyson

Sat 9/13

11:07 am-7:12 pm

2 stops10h 05m

Guatemala City La Aurora

Sat 10/4

6:30 am-11:03 pm

2 stops14h 33m

$612

KnoxvilleGuatemala City

TYS - GUA

TYSGUA

Knoxville McGhee Tyson

Mon 9/8

7:28 am-5:14 pm

1 stop11h 46m

Guatemala City La Aurora

Sat 10/4

12:30 pm-11:50 pm

1 stop9h 20m

$652

KnoxvilleGuatemala City

TYS - GUA

TYSGUA

Knoxville McGhee Tyson

Mon 9/8

5:05 am-7:12 pm

2 stops16h 07m

Guatemala City La Aurora

Sat 10/4

12:30 pm-11:50 pm

1 stop9h 20m

$656

KnoxvilleGuatemala City

TYS - GUA

TYSGUA

Knoxville McGhee Tyson

Sat 9/13

7:29 am-7:12 pm

2 stops13h 43m

Guatemala City La Aurora

Sat 10/4

8:30 am-8:50 pm

2 stops10h 20m

$659

KnoxvilleGuatemala City

TYS - GUA

TYSGUA

Knoxville McGhee Tyson

Sat 9/13

9:30 am-4:32 pm

1 stop9h 02m

Guatemala City La Aurora

Fri 10/3

1:30 am-7:52 pm

1 stop16h 22m

$697

KnoxvilleGuatemala City

TYS - GUA

TYSGUA

Knoxville McGhee Tyson

Mon 9/8

12:00 pm-4:32 pm

1 stop6h 32m

Guatemala City La Aurora

Fri 10/3

1:30 am-6:10 pm

1 stop14h 40m

$720

KnoxvilleGuatemala City

TYS - GUA

TYSGUA

Knoxville McGhee Tyson

Sat 9/13

9:30 am-4:32 pm

1 stop9h 02m

Guatemala City La Aurora

Fri 10/3

1:30 am-6:10 pm

1 stop14h 40m

$740

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 13 resultsSorted by cheapest first
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See travel insights to Guatemala from

How to get the cheapest flight ticket from Knoxville to Guatemala

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Guatemala?

In general, August is the cheapest month to fly from Knoxville to Guatemala. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $469. The month of April is another great option to travel to Guatemala, with average flight prices from Knoxville averaging around $482.

What is the cheapest day to depart on your flight to Guatemala?

Our data shows that Tuesday is the least expensive day to fly to Guatemala. Tickets to fly out on this day can be as low as $485. The most expensive day to fly to Guatemala is Saturday, with ticket prices averaging around $740.

What is the cheapest time of day to depart on your flight to Guatemala?

According to our data, the cheapest time of day to fly to Guatemala is in the afternoon. momondo users have found flights departing from Knoxville to Guatemala in the afternoon for as low as $550. Keep in mind that these prices may fluctuate based on what airline you choose and the time of year you plan to travel. Flights to Guatemala are more costly in the morning, with an average ticket price of $630. Departure times in the morning fall within the peak daily travel times, which is why tickets can be more expensive.

Cheap Knoxville to Guatemala flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Knoxville to Guatemala

Direct flights

None
There are no direct flights from Knoxville to Guatemala. There are no popular flight routes from Knoxville to Guatemala.
Search flight deals

  • When did momondo last update prices for flights from Knoxville McGhee Tyson Airport to Guatemala?

    Prices for flights from Knoxville McGhee Tyson Airport to Guatemala are refreshed on a daily basis.

  • How many operators does momondo search for flights from Knoxville McGhee Tyson Airport to Guatemala?

  • How old do you have to be to fly from Knoxville McGhee Tyson Airport to Guatemala?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Knoxville McGhee Tyson Airport to Guatemala.

  • What documentation or ID do you need to fly to Guatemala?

    The travel and health documents required for your trip to Guatemala can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Guatemala. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Best airlines flying from Knoxville to Guatemala

Compare and see reviews for airlines that fly from Knoxville to Guatemala with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $463Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Knoxville to Guatemala?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Knoxville to Guatemala. momondo saves you time and could save you money on your trip.

Can I find flights from Knoxville to Guatemala with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Guatemala from Knoxville with this policy.

How can momondo help me find flights from Knoxville to Guatemala?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Knoxville to Guatemala.

I’m not ready to book a flight from Knoxville to Guatemala right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Guatemala, momondo offers a useful price alert feature which will track prices for flights to Guatemala from Knoxville and alert you when they change.

An easier way to manage your Guatemala trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
Start using Trips
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