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Cheap flights from Knoxville to Guatemala from $349

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Knoxville to Guatemala departing on 2/23. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Knoxville to Guatemala

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
7:15 am - 6:35 pm
TYS
-
GUA
36h 20m2 stops
Multiple Airlines Logo
7:10 pm - 10:07 pm
GUA
-
TYS
25h 57m1 stop
$349Multiple Airlines
Mon, Feb 23 - Sat, Feb 28
Multiple Airlines Logo
6:00 am - 1:16 pm
TYS
-
GUA
32h 16m2 stops
Multiple Airlines Logo
12:15 pm - 4:59 pm
GUA
-
TYS
27h 44m1 stop
$366Multiple Airlines
Mon, Feb 9 - Thu, Feb 26
Multiple Airlines Logo
6:18 pm - 11:20 am
TYS
-
GUA
18h 02m1 stop
Multiple Airlines Logo
12:15 pm - 4:59 pm
GUA
-
TYS
27h 44m1 stop
$373Multiple Airlines
Mon, Feb 9 - Thu, Feb 26
Multiple Airlines Logo
12:55 pm - 11:20 am
TYS
-
GUA
23h 25m1 stop
Multiple Airlines Logo
7:10 pm - 10:07 pm
GUA
-
TYS
25h 57m1 stop
$377Multiple Airlines
Mon, Feb 23 - Sat, Feb 28
Multiple Airlines Logo
12:55 pm - 1:16 pm
TYS
-
GUA
25h 21m2 stops
Multiple Airlines Logo
1:29 pm - 1:04 pm
GUA
-
TYS
22h 35m2 stops
$435Multiple Airlines
Mon, Feb 9 - Thu, Feb 26
Multiple Airlines Logo
12:55 pm - 1:16 pm
TYS
-
GUA
25h 21m3 stops
Multiple Airlines Logo
1:29 pm - 1:04 pm
GUA
-
TYS
22h 35m2 stops
$437Multiple Airlines
Mon, Feb 9 - Thu, Feb 26
Multiple Airlines Logo
9:36 pm - 12:24 pm
TYS
-
GUA
15h 48m1 stop
Multiple Airlines Logo
10:26 pm - 6:58 pm
GUA
-
TYS
19h 32m2 stops
$451Multiple Airlines
Mon, Mar 2 - Fri, Mar 6
Multiple Airlines Logo
12:55 pm - 1:16 pm
TYS
-
GUA
25h 21m3 stops
Multiple Airlines Logo
12:15 pm - 8:46 pm
GUA
-
TYS
31h 31m3 stops
$470Multiple Airlines
Mon, Feb 9 - Thu, Feb 26
Multiple Airlines Logo
4:47 pm - 1:16 pm
TYS
-
GUA
21h 29m2 stops
Multiple Airlines Logo
12:15 pm - 5:28 pm
GUA
-
TYS
28h 13m1 stop
$476Multiple Airlines
Wed, Jan 14 - Sun, Jan 18
Multiple Airlines Logo
12:55 pm - 11:20 am
TYS
-
GUA
23h 25m1 stop
Multiple Airlines Logo
1:29 pm - 9:40 am
GUA
-
TYS
19h 11m1 stop
$477Multiple Airlines
Mon, Mar 2 - Fri, Mar 6

American Airlines flights from Knoxville to Guatemala

Our best American Airlines deals on Knoxville to Guatemala flight tickets
American Airlines
Feb 10
TYS6:20 amKnoxville McGhee Tyson
9h 31m
1 stop
GUA2:51 pmGuatemala City La Aurora
Feb 18
GUA7:00 amGuatemala City La Aurora
10h 32m
1 stop
TYS6:32 pmKnoxville McGhee Tyson
$526
Find similar
American Airlines
Feb 10
TYS6:51 pmKnoxville McGhee Tyson
21h 00m
2 stops
GUA2:51 pmGuatemala City La Aurora
Feb 18
GUA2:06 pmGuatemala City La Aurora
17h 35m
2 stops
TYS8:41 amKnoxville McGhee Tyson
$530
Find similar
American Airlines
Mar 27
TYS6:00 amKnoxville McGhee Tyson
7h 48m
1 stop
GUA11:48 amGuatemala City La Aurora
Apr 8
GUA1:15 pmGuatemala City La Aurora
7h 59m
1 stop
TYS11:14 pmKnoxville McGhee Tyson
$534
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Knoxville to Guatemala that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated December 13, 2025.
Use the filters below to find and compare flights from Knoxville to Guatemala that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

KnoxvilleGuatemala City

TYS - GUA

TYSGUA

Knoxville McGhee Tyson

Mon 2/23

7:15 am-6:35 pm

2 stops36h 20m

Guatemala City La Aurora

Sat 2/28

7:10 pm-10:07 pm

1 stop25h 57m

$349

KnoxvilleGuatemala City

TYS - GUA

TYSGUA

Knoxville McGhee Tyson

Mon 2/9

6:00 am-1:16 pm

2 stops32h 16m

Guatemala City La Aurora

Thu 2/26

12:15 pm-4:59 pm

1 stop27h 44m

$366

KnoxvilleGuatemala City

TYS - GUA

TYSGUA

Knoxville McGhee Tyson

Mon 2/9

6:18 pm-11:20 am

1 stop18h 02m

Guatemala City La Aurora

Thu 2/26

12:15 pm-4:59 pm

1 stop27h 44m

$373

KnoxvilleGuatemala City

TYS - GUA

TYSGUA

Knoxville McGhee Tyson

Mon 2/23

12:55 pm-11:20 am

1 stop23h 25m

Guatemala City La Aurora

Sat 2/28

7:10 pm-10:07 pm

1 stop25h 57m

$377

KnoxvilleGuatemala City

TYS - GUA

TYSGUA

Knoxville McGhee Tyson

Mon 2/9

12:55 pm-1:16 pm

2 stops25h 21m

Guatemala City La Aurora

Thu 2/26

1:29 pm-1:04 pm

2 stops22h 35m

$435

KnoxvilleGuatemala City

TYS - GUA

TYSGUA

Knoxville McGhee Tyson

Mon 2/9

12:55 pm-1:16 pm

3 stops25h 21m

Guatemala City La Aurora

Thu 2/26

1:29 pm-1:04 pm

2 stops22h 35m

$437

KnoxvilleGuatemala City

TYS - GUA

TYSGUA

Knoxville McGhee Tyson

Mon 3/2

9:36 pm-12:24 pm

1 stop15h 48m

Guatemala City La Aurora

Fri 3/6

10:26 pm-6:58 pm

2 stops19h 32m

$451

KnoxvilleGuatemala City

TYS - GUA

TYSGUA

Knoxville McGhee Tyson

Mon 2/9

12:55 pm-1:16 pm

3 stops25h 21m

Guatemala City La Aurora

Thu 2/26

12:15 pm-8:46 pm

3 stops31h 31m

$470

KnoxvilleGuatemala City

TYS - GUA

TYSGUA

Knoxville McGhee Tyson

Wed 1/14

4:47 pm-1:16 pm

2 stops21h 29m

Guatemala City La Aurora

Sun 1/18

12:15 pm-5:28 pm

1 stop28h 13m

$476

KnoxvilleGuatemala City

TYS - GUA

TYSGUA

Knoxville McGhee Tyson

Mon 3/2

12:55 pm-11:20 am

1 stop23h 25m

Guatemala City La Aurora

Fri 3/6

1:29 pm-9:40 am

1 stop19h 11m

$477

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

See travel insights to Guatemala from

How to get the cheapest flight ticket from Knoxville to Guatemala

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to Guatemala?

Our data shows that Tuesday is the least expensive day to fly to Guatemala. Tickets to fly out on this day can be as low as $485. The most expensive day to fly to Guatemala is Saturday, with ticket prices averaging around $740.

What is the cheapest time of day to depart on your flight to Guatemala?

According to our data, the cheapest time of day to fly to Guatemala is in the afternoon. momondo users have found flights departing from Knoxville to Guatemala in the afternoon for as low as $550. Keep in mind that these prices may fluctuate based on what airline you choose and the time of year you plan to travel. Flights to Guatemala are more costly in the morning, with an average ticket price of $630. Departure times in the morning fall within the peak daily travel times, which is why tickets can be more expensive.

Cheap Knoxville to Guatemala flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Knoxville to Guatemala

Fastest flight time

8h 05m

Direct flights

None
The fastest flight from Knoxville to Guatemala takes 8h 05m
There are no direct flights from Knoxville to Guatemala. There are no popular flight routes from Knoxville to Guatemala.
Search flight deals

  • When did momondo last update prices for flights from Knoxville McGhee Tyson Airport to Guatemala?

    Prices for flights from Knoxville McGhee Tyson Airport to Guatemala are refreshed on a daily basis.

  • How many operators does momondo search for flights from Knoxville McGhee Tyson Airport to Guatemala?

  • How old do you have to be to fly from Knoxville McGhee Tyson Airport to Guatemala?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Knoxville McGhee Tyson Airport to Guatemala.

  • What documentation or ID do you need to fly to Guatemala?

    The travel and health documents required for your trip to Guatemala can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Guatemala. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Best airlines flying from Knoxville to Guatemala

Compare and see reviews for airlines that fly from Knoxville to Guatemala with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $463Free CancellationRating
7.2
11,054 reviews
Search American Airlines flights
DeltaPriceFrom $504Free CancellationRating
7.9
8,007 reviews
Search Delta flights

Why use momondo?

Why should I use momondo to find a flight deal from Knoxville to Guatemala?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Knoxville to Guatemala. momondo saves you time and could save you money on your trip.

Can I find flights from Knoxville to Guatemala with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Guatemala from Knoxville with this policy.

How can momondo help me find flights from Knoxville to Guatemala?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Knoxville to Guatemala.

I’m not ready to book a flight from Knoxville to Guatemala right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Guatemala, momondo offers a useful price alert feature which will track prices for flights to Guatemala from Knoxville and alert you when they change.

An easier way to manage your Guatemala trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
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