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Cheap flights from Knoxville to Guatemala from $378

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Knoxville to Guatemala departing on 2/19. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
5:56 pm - 1:29 pmTYS-GUA
44h 33m2 stops
Multiple Airlines Logo
7:10 pm - 10:07 pmGUA-TYS
25h 57m1 stop
$378Multiple Airlines
Find Deal
Thu, Feb 19 - Sat, Feb 28
Multiple Airlines Logo
9:32 pm - 12:24 pmTYS-GUA
15h 52m1 stop
Multiple Airlines Logo
7:10 pm - 10:07 pmGUA-TYS
25h 57m1 stop
$402Multiple Airlines
Find Deal
Thu, Feb 19 - Sat, Feb 28
Multiple Airlines Logo
9:32 pm - 12:24 pmTYS-GUA
15h 52m1 stop
Multiple Airlines Logo
1:29 pm - 8:52 pmGUA-TYS
30h 23m3 stops
$500Multiple Airlines
Find Deal
Thu, Feb 19 - Sat, Feb 28
Multiple Airlines Logo
5:56 pm - 7:41 amTYS-GUA
14h 45m2 stops
Multiple Airlines Logo
1:29 pm - 8:52 pmGUA-TYS
30h 23m3 stops
$521Multiple Airlines
Find Deal
Thu, Feb 19 - Sat, Feb 28
Multiple Airlines Logo
5:56 pm - 4:13 pmTYS-GUA
23h 17m3 stops
Multiple Airlines Logo
1:29 pm - 8:52 pmGUA-TYS
30h 23m3 stops
$602Multiple Airlines
Find Deal
Thu, Feb 19 - Sat, Feb 28
United Airlines Logo
7:05 am - 12:26 pmTYS-GUA
6h 21m1 stop
United Airlines Logo
2:10 am - 6:10 pmGUA-TYS
15h 00m1 stop
$626United Airlines
Find Deal
Thu, Feb 19 - Fri, Feb 27
United Airlines Logo
11:40 am - 7:39 pmTYS-GUA
8h 59m1 stop
United Airlines Logo
2:10 am - 7:50 pmGUA-TYS
16h 40m1 stop
$642United Airlines
Find Deal
Mon, Jan 26 - Wed, Jan 28
American Airlines Logo
6:51 pm - 1:13 pmTYS-GUA
19h 22m2 stops
American Airlines Logo
4:02 pm - 11:59 pmGUA-TYS
6h 57m1 stop
$646American Airlines
Find Deal
Mon, Jan 26 - Thu, Jan 29
American Airlines Logo
6:20 am - 1:13 pmTYS-GUA
7h 53m1 stop
American Airlines Logo
6:32 am - 3:46 pmGUA-TYS
8h 14m1 stop
$662American Airlines
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Mon, Jan 26 - Thu, Jan 29
American Airlines Logo
11:19 am - 9:05 pmTYS-GUA
10h 46m2 stops
American Airlines Logo
7:00 am - 8:56 pmGUA-TYS
12h 56m2 stops
$666American Airlines
Find Deal
Mon, Jan 26 - Thu, Jan 29

United Airlines flights from Knoxville to Guatemala

Our best United Airlines deals on Knoxville to Guatemala flight tickets
United Airlines
Feb 19
TYS7:05 amKnoxville McGhee Tyson
6h 21m
1 stop
GUA12:26 pmGuatemala City La Aurora
Feb 27
GUA2:10 amGuatemala City La Aurora
15h 00m
1 stop
TYS6:10 pmKnoxville McGhee Tyson
$626
Find similar
United Airlines
Jan 26
TYS11:40 amKnoxville McGhee Tyson
8h 59m
1 stop
GUA7:39 pmGuatemala City La Aurora
Jan 28
GUA2:10 amGuatemala City La Aurora
16h 40m
1 stop
TYS7:50 pmKnoxville McGhee Tyson
$642
Find similar

American Airlines flights from Knoxville to Guatemala

Our best American Airlines deals on Knoxville to Guatemala flight tickets
American Airlines
Jan 26
TYS6:51 pmKnoxville McGhee Tyson
19h 22m
2 stops
GUA1:13 pmGuatemala City La Aurora
Jan 29
GUA4:02 pmGuatemala City La Aurora
6h 57m
1 stop
TYS11:59 pmKnoxville McGhee Tyson
$646
Find similar
American Airlines
Jan 26
TYS6:20 amKnoxville McGhee Tyson
7h 53m
1 stop
GUA1:13 pmGuatemala City La Aurora
Jan 29
GUA6:32 amGuatemala City La Aurora
8h 14m
1 stop
TYS3:46 pmKnoxville McGhee Tyson
$662
Find similar
American Airlines
Jan 26
TYS11:19 amKnoxville McGhee Tyson
10h 46m
2 stops
GUA9:05 pmGuatemala City La Aurora
Jan 29
GUA7:00 amGuatemala City La Aurora
12h 56m
2 stops
TYS8:56 pmKnoxville McGhee Tyson
$666
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Knoxville to Guatemala that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated November 30, 2025.
Use the filters below to find and compare flights from Knoxville to Guatemala that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

KnoxvilleGuatemala City

TYS - GUA

TYSGUA

Knoxville McGhee Tyson

Thu 2/19

5:56 pm-1:29 pm

2 stops44h 33m

Guatemala City La Aurora

Sat 2/28

7:10 pm-10:07 pm

1 stop25h 57m

$378

KnoxvilleGuatemala City

TYS - GUA

TYSGUA

Knoxville McGhee Tyson

Thu 2/19

9:32 pm-12:24 pm

1 stop15h 52m

Guatemala City La Aurora

Sat 2/28

7:10 pm-10:07 pm

1 stop25h 57m

$402

KnoxvilleGuatemala City

TYS - GUA

TYSGUA

Knoxville McGhee Tyson

Thu 2/19

9:32 pm-12:24 pm

1 stop15h 52m

Guatemala City La Aurora

Sat 2/28

1:29 pm-8:52 pm

3 stops30h 23m

$500

KnoxvilleGuatemala City

TYS - GUA

TYSGUA

Knoxville McGhee Tyson

Thu 2/19

5:56 pm-7:41 am

2 stops14h 45m

Guatemala City La Aurora

Sat 2/28

1:29 pm-8:52 pm

3 stops30h 23m

$521

KnoxvilleGuatemala City

TYS - GUA

TYSGUA

Knoxville McGhee Tyson

Thu 2/19

5:56 pm-4:13 pm

3 stops23h 17m

Guatemala City La Aurora

Sat 2/28

1:29 pm-8:52 pm

3 stops30h 23m

$602

KnoxvilleGuatemala City

TYS - GUA

TYSGUA

Knoxville McGhee Tyson

Thu 2/19

7:05 am-12:26 pm

1 stop6h 21m

Guatemala City La Aurora

Fri 2/27

2:10 am-6:10 pm

1 stop15h 00m

$626

KnoxvilleGuatemala City

TYS - GUA

TYSGUA

Knoxville McGhee Tyson

Mon 1/26

11:40 am-7:39 pm

1 stop8h 59m

Guatemala City La Aurora

Wed 1/28

2:10 am-7:50 pm

1 stop16h 40m

$642

KnoxvilleGuatemala City

TYS - GUA

TYSGUA

Knoxville McGhee Tyson

Mon 1/26

6:51 pm-1:13 pm

2 stops19h 22m

Guatemala City La Aurora

Thu 1/29

4:02 pm-11:59 pm

1 stop6h 57m

$646

KnoxvilleGuatemala City

TYS - GUA

TYSGUA

Knoxville McGhee Tyson

Mon 1/26

6:20 am-1:13 pm

1 stop7h 53m

Guatemala City La Aurora

Thu 1/29

6:32 am-3:46 pm

1 stop8h 14m

$662

KnoxvilleGuatemala City

TYS - GUA

TYSGUA

Knoxville McGhee Tyson

Mon 1/26

11:19 am-9:05 pm

2 stops10h 46m

Guatemala City La Aurora

Thu 1/29

7:00 am-8:56 pm

2 stops12h 56m

$666

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 16 resultsSorted by cheapest first
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See travel insights to Guatemala from

How to get the cheapest flight ticket from Knoxville to Guatemala

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to Guatemala?

Our data shows that Tuesday is the least expensive day to fly to Guatemala. Tickets to fly out on this day can be as low as $485. The most expensive day to fly to Guatemala is Saturday, with ticket prices averaging around $740.

What is the cheapest time of day to depart on your flight to Guatemala?

According to our data, the cheapest time of day to fly to Guatemala is in the afternoon. momondo users have found flights departing from Knoxville to Guatemala in the afternoon for as low as $550. Keep in mind that these prices may fluctuate based on what airline you choose and the time of year you plan to travel. Flights to Guatemala are more costly in the morning, with an average ticket price of $630. Departure times in the morning fall within the peak daily travel times, which is why tickets can be more expensive.

Cheap Knoxville to Guatemala flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Knoxville to Guatemala

Fastest flight time

15h 35m

Direct flights

None
The fastest flight from Knoxville to Guatemala takes 15h 35m
There are no direct flights from Knoxville to Guatemala. There are no popular flight routes from Knoxville to Guatemala.
Search flight deals

  • When did momondo last update prices for flights from Knoxville McGhee Tyson Airport to Guatemala?

    Prices for flights from Knoxville McGhee Tyson Airport to Guatemala are refreshed on a daily basis.

  • How many operators does momondo search for flights from Knoxville McGhee Tyson Airport to Guatemala?

  • How old do you have to be to fly from Knoxville McGhee Tyson Airport to Guatemala?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Knoxville McGhee Tyson Airport to Guatemala.

  • What documentation or ID do you need to fly to Guatemala?

    The travel and health documents required for your trip to Guatemala can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Guatemala. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Best airlines flying from Knoxville to Guatemala

Compare and see reviews for airlines that fly from Knoxville to Guatemala with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $463Free CancellationRating
7.2
11,042 reviews
Search American Airlines flights
DeltaPriceFrom $504Free CancellationRating
7.9
8,011 reviews
Search Delta flights

Why use momondo?

Why should I use momondo to find a flight deal from Knoxville to Guatemala?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Knoxville to Guatemala. momondo saves you time and could save you money on your trip.

Can I find flights from Knoxville to Guatemala with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Guatemala from Knoxville with this policy.

How can momondo help me find flights from Knoxville to Guatemala?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Knoxville to Guatemala.

I’m not ready to book a flight from Knoxville to Guatemala right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Guatemala, momondo offers a useful price alert feature which will track prices for flights to Guatemala from Knoxville and alert you when they change.

An easier way to manage your Guatemala trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
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