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Cheap flights from Knoxville to Cancún from $375

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Knoxville to Cancún departing on 12/8. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Knoxville to Cancún

Cheap round-trip flights

Enter your travel dates to find the best prices.
United Airlines Logo
7:20 pm - 2:42 pmTYS  Knoxville McGhee Tyson-CZM Cozumel Intl
20h 22m2 stops Washington, D.C. Dulles Intl Houston George Bush Intcntl
United Airlines Logo
3:52 pm - 9:45 amCZM  Cozumel Intl-TYS Knoxville McGhee Tyson
16h 53m2 stops Houston George Bush Intcntl Chicago O'Hare Intl
$585United Airlines
Tue, Sep 1 - Tue, Sep 29
United Airlines Logo
7:15 am - 2:42 pmTYS  Knoxville McGhee Tyson-CZM Cozumel Intl
8h 27m1 stop Houston George Bush Intcntl
United Airlines Logo
3:52 pm - 9:45 amCZM  Cozumel Intl-TYS Knoxville McGhee Tyson
16h 53m2 stops Houston George Bush Intcntl Chicago O'Hare Intl
$585United Airlines
Tue, Sep 1 - Tue, Sep 29
United Airlines Logo
7:25 pm - 2:42 pmTYS  Knoxville McGhee Tyson-CZM Cozumel Intl
20h 17m2 stops Washington, D.C. Dulles Intl Houston George Bush Intcntl
United Airlines Logo
3:50 pm - 9:53 amCZM  Cozumel Intl-TYS Knoxville McGhee Tyson
17h 03m2 stops Houston George Bush Intcntl Chicago O'Hare Intl
$610United Airlines
Mon, Oct 19 - Mon, Oct 26
American Airlines Logo
6:00 am - 1:55 pmTYS  Knoxville McGhee Tyson-CZM Cozumel Intl
8h 55m1 stop Miami
American Airlines Logo
2:35 pm - 11:09 pmCZM  Cozumel Intl-TYS Knoxville McGhee Tyson
7h 34m1 stop Miami
$611American Airlines
Mon, Oct 19 - Mon, Oct 26
American Airlines Logo
7:16 pm - 2:22 pmTYS  Knoxville McGhee Tyson-CZM Cozumel Intl
19h 06m2 stops Miami Dallas/Fort Worth
American Airlines Logo
5:24 pm - 10:33 amCZM  Cozumel Intl-TYS Knoxville McGhee Tyson
17h 09m2 stops Dallas/Fort Worth Charlotte Douglas
$612American Airlines
Sat, Nov 14 - Sat, Nov 21
American Airlines Logo
8:30 pm - 2:22 pmTYS  Knoxville McGhee Tyson-CZM Cozumel Intl
17h 52m2 stops Chicago O'Hare Intl Dallas/Fort Worth
American Airlines Logo
1:54 pm - 7:36 pmCZM  Cozumel Intl-TYS Knoxville McGhee Tyson
5h 42m1 stop Charlotte Douglas
$612American Airlines
Sat, Nov 14 - Sat, Nov 21
American Airlines Logo
7:58 pm - 1:55 pmTYS  Knoxville McGhee Tyson-CZM Cozumel Intl
18h 57m2 stops Charlotte Douglas Miami
American Airlines Logo
2:25 pm - 12:01 pmCZM  Cozumel Intl-TYS Knoxville McGhee Tyson
20h 36m2 stops Dallas/Fort Worth Chicago O'Hare Intl
$615American Airlines
Sat, Oct 24 - Sat, Oct 31
American Airlines Logo
7:58 pm - 1:25 pmTYS  Knoxville McGhee Tyson-CZM Cozumel Intl
18h 27m2 stops Charlotte Douglas Dallas/Fort Worth
American Airlines Logo
2:25 pm - 11:18 pmCZM  Cozumel Intl-TYS Knoxville McGhee Tyson
7h 53m1 stop Dallas/Fort Worth
$615American Airlines
Sat, Oct 24 - Sat, Oct 31
American Airlines Logo
6:55 pm - 1:55 pmTYS  Knoxville McGhee Tyson-CZM Cozumel Intl
20h 00m2 stops Chicago O'Hare Intl Miami
American Airlines Logo
2:15 pm - 11:18 pmCZM  Cozumel Intl-TYS Knoxville McGhee Tyson
8h 03m1 stop Dallas/Fort Worth
$615American Airlines
Mon, Oct 19 - Mon, Oct 26
American Airlines Logo
5:32 pm - 2:22 pmTYS  Knoxville McGhee Tyson-CZM Cozumel Intl
20h 50m1 stop Dallas/Fort Worth
American Airlines Logo
1:54 pm - 9:41 pmCZM  Cozumel Intl-TYS Knoxville McGhee Tyson
7h 47m1 stop Charlotte Douglas
$619American Airlines
Sat, Nov 14 - Sat, Nov 21

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Aeromexico flights from Knoxville to Cozumel

Our best Aeromexico deals on Knoxville to Cozumel flight tickets
Aeromexico
Feb 2
TYS4:00 pmKnoxville McGhee Tyson
22h 15m
2 stops
CZM2:15 pmCozumel Intl
Feb 7
CZM3:05 pmCozumel Intl
8h 41m
1 stop
TYS11:46 pmKnoxville McGhee Tyson
$819
Aeromexico
Aug 10
TYS6:12 pmKnoxville McGhee Tyson
21h 30m
2 stops
CZM2:42 pmCozumel Intl
Aug 24
CZM4:29 pmCozumel Intl
30h 23m
2 stops
TYS11:52 pmKnoxville McGhee Tyson
$1,316

American Airlines flights from Knoxville to Cozumel

Our best American Airlines deals on Knoxville to Cozumel flight tickets
American Airlines
Oct 19
TYS6:00 amKnoxville McGhee Tyson
8h 55m
1 stop
CZM1:55 pmCozumel Intl
Oct 26
CZM2:35 pmCozumel Intl
7h 34m
1 stop
TYS11:09 pmKnoxville McGhee Tyson
$611
American Airlines
Nov 14
TYS7:16 pmKnoxville McGhee Tyson
19h 06m
2 stops
CZM2:22 pmCozumel Intl
Nov 21
CZM5:24 pmCozumel Intl
17h 09m
2 stops
TYS10:33 amKnoxville McGhee Tyson
$612
American Airlines
Oct 24
TYS7:58 pmKnoxville McGhee Tyson
18h 27m
2 stops
CZM1:25 pmCozumel Intl
Oct 31
CZM2:25 pmCozumel Intl
7h 53m
1 stop
TYS11:18 pmKnoxville McGhee Tyson
$615

momondo Fare Finder

 
Customize your flight search to find flights from Knoxville to Cozumel that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 9, 2026.
Use the filters below to find and compare flights from Knoxville to Cozumel that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

KnoxvilleCozumel

TYS Knoxville McGhee Tyson - CZM Cozumel Intl

TYSCZM

Knoxville McGhee Tyson

Tue 9/1

7:20 pm-2:42 pm

2 stops20h 22m

Cozumel Intl

Tue 9/29

3:52 pm-9:45 am

2 stops16h 53m

$585

KnoxvilleCozumel

TYS Knoxville McGhee Tyson - CZM Cozumel Intl

TYSCZM

Knoxville McGhee Tyson

Tue 9/1

7:15 am-2:42 pm

1 stop8h 27m

Cozumel Intl

Tue 9/29

3:52 pm-9:45 am

2 stops16h 53m

$585

KnoxvilleCozumel

TYS Knoxville McGhee Tyson - CZM Cozumel Intl

TYSCZM

Knoxville McGhee Tyson

Mon 10/19

7:25 pm-2:42 pm

2 stops20h 17m

Cozumel Intl

Mon 10/26

3:50 pm-9:53 am

2 stops17h 03m

$610
Quickest round-trip

KnoxvilleCozumel

TYS Knoxville McGhee Tyson - CZM Cozumel Intl

TYSCZM

Knoxville McGhee Tyson

Mon 10/19

6:00 am-1:55 pm

1 stop8h 55m

Cozumel Intl

Mon 10/26

2:35 pm-11:09 pm

1 stop7h 34m

$611

KnoxvilleCozumel

TYS Knoxville McGhee Tyson - CZM Cozumel Intl

TYSCZM

Knoxville McGhee Tyson

Sat 11/14

7:16 pm-2:22 pm

2 stops19h 06m

Cozumel Intl

Sat 11/21

5:24 pm-10:33 am

2 stops17h 09m

$612

KnoxvilleCozumel

TYS Knoxville McGhee Tyson - CZM Cozumel Intl

TYSCZM

Knoxville McGhee Tyson

Sat 11/14

8:30 pm-2:22 pm

2 stops17h 52m

Cozumel Intl

Sat 11/21

1:54 pm-7:36 pm

1 stop5h 42m

$612

KnoxvilleCozumel

TYS Knoxville McGhee Tyson - CZM Cozumel Intl

TYSCZM

Knoxville McGhee Tyson

Sat 10/24

7:58 pm-1:55 pm

2 stops18h 57m

Cozumel Intl

Sat 10/31

2:25 pm-12:01 pm

2 stops20h 36m

$615

KnoxvilleCozumel

TYS Knoxville McGhee Tyson - CZM Cozumel Intl

TYSCZM

Knoxville McGhee Tyson

Sat 10/24

7:58 pm-1:25 pm

2 stops18h 27m

Cozumel Intl

Sat 10/31

2:25 pm-11:18 pm

1 stop7h 53m

$615

KnoxvilleCozumel

TYS Knoxville McGhee Tyson - CZM Cozumel Intl

TYSCZM

Knoxville McGhee Tyson

Mon 10/19

6:55 pm-1:55 pm

2 stops20h 00m

Cozumel Intl

Mon 10/26

2:15 pm-11:18 pm

1 stop8h 03m

$615

KnoxvilleCozumel

TYS Knoxville McGhee Tyson - CZM Cozumel Intl

TYSCZM

Knoxville McGhee Tyson

Sat 11/14

5:32 pm-2:22 pm

1 stop20h 50m

Cozumel Intl

Sat 11/21

1:54 pm-9:41 pm

1 stop7h 47m

$619

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Knoxville to Cozumel

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest airline that flies from Knoxville McGhee Tyson to Cozumel Intl?

United Airlines is the most popular carrier operating from Knoxville McGhee Tyson to Cozumel Intl

What airlines fly to Cozumel?

American Airlines, Delta and United Airlines are the top three most popular airlines that fly to Cozumel from Knoxville according to our data. American Airlines is the first choice among our users, with 62% of people opting to fly with this airline when traveling to Cozumel. Keep in mind that there are 5 different airlines that fly to Cozumel on a routine basis, so you have a few additional options to choose from.

When to book flights from Knoxville to Cozumel

Are you open to changing your travel dates? Check out the ideal times to fly from Knoxville to Cozumel according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Knoxville to Cozumel (TYS to CZM) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Knoxville to Cozumel

Fastest flight time

5h 03m

Direct flights

None
The fastest flight from Knoxville to Cozumel takes 5h 03m
There are no direct flights from Knoxville to Cozumel. There are no popular flight routes from Knoxville to Cozumel.
Search flight deals

Frequently asked questions about flying from Knoxville to Cozumel

  • How far is Knoxville McGhee Tyson to Cozumel Intl by plane?

    The straight-line distance from Knoxville McGhee Tyson to Cozumel Intl is 1083.2 mi. A reasonable flight in good conditions will take 5h 03m.

  • When did momondo last update prices for flights from Knoxville McGhee Tyson Airport to Cozumel Intl Airport?

    Prices for flights from Knoxville McGhee Tyson Airport to Cozumel Intl Airport were last updated today.

  • How many operators does momondo search for flights from Knoxville McGhee Tyson Airport to Cozumel Intl Airport?

  • How old do you have to be to fly from Knoxville McGhee Tyson Airport to Cozumel Intl Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Knoxville McGhee Tyson Airport to Cozumel Intl Airport.

  • What documentation or ID do you need to fly to Cozumel Intl Airport?

    The travel and health documents you'll need for your trip to Cozumel Intl Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Cozumel Intl Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Knoxville to Cozumel?

Best airlines flying from Knoxville to Cozumel

Compare and see reviews for airlines that fly from Knoxville to Cozumel with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $599Free CancellationRating
7.1
11,899 reviews
Search American Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Knoxville to Cozumel?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Knoxville to Cozumel for you.

Can I find flights from Knoxville to Cozumel with flexible booking policies on momondo?

momondo does allow users to show only those flights to Cozumel from Knoxville which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Knoxville to Cozumel?

Once you have performed a search for Knoxville to Cozumel flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Knoxville to Cozumel right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Cozumel from Knoxville. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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