Cheap flights from Istanbul Airport to Chicago from $363

The month of April is, on average, the cheapest month to fly to Chicago from Istanbul Airport, with most prices found around $658. If you’re not able to fly to Chicago in April, then January is your next best option. Flight prices from Istanbul Airport to Chicago during January average around $664.

The cheapest day to depart on your flight to Chicago is on a Sunday when prices can be found for as low as $779. This is often the case because there is less demand to fly during this day of the week. When flying out on a Thursday, the most expensive travel day of the week, you can expect to see flight prices from Istanbul Airport to Chicago for around $837.

Our most recent data shows that the best time of day to fly to Chicago is in the morning. Flights from Istanbul Airport to Chicago during this time can be as low as $788. In contrast, the most expensive time of day to depart to Chicago is in the afternoon when prices are around $837.

Fly from Istanbul to Chicago O'Hare Intl for the best Istanbul - Chicago flight prices

You are more likely to see cheaper flights to Chicago from Istanbul Airport when booking weeks ahead of your departure date. In general, you can expect to find flights to Chicago for around $772 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Chicago from Istanbul Airport for as low as $614 on momondo.

There are 3 cabin classes available to choose from on Istanbul to Chicago flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

British Airways and Air Serbia are the most popular carriers operating from Istanbul to Chicago

Turkish Airlines, Lufthansa and LOT are the top three most popular airlines that fly to Chicago from Istanbul Airport according to our data. Turkish Airlines is the first choice among our users, with 77% of people opting to fly with this airline when traveling to Chicago. Keep in mind that there are 4 different airlines that fly to Chicago on a routine basis, so you have a few additional options to choose from.

Historically, on average around 17% of flights between Istanbul and Chicago have experienced a delay on any given week. The average delay length over the past 12 months has been 204 minutes.

Generally, flights departing in the morning tend to experience fewer delays. Flights at night have, in the past, seen delays more frequently in comparison.

Monday is statistically the day of the week which experiences the fewest number of delays on this flight route. Wednesday has historically seen more delays on average compared to the rest of the week.

According to our data, Turkish Airlines have had the least number of delays on this route over the last 12 months; with about 16% of their flights experiencing any sort of delay.

Warsaw (WAW) was the most common stop: 57% of momondo users choosing 1-stop flights on this route connected there.

Flights via Amsterdam (AMS) offer the lowest average round-trip price of $506.

Flights connecting via Frankfurt am Main (FRA) have the shortest average one-way travel time: 14h 33m.

Frankfurt am Main (FRA) has the shortest average layover time for this route: 2h 39m.

As of April 2026, there are 9 flights per day flying from Istanbul Airport to Chicago. The most common time of day flights depart is 7:00AM, with 58% of flights taking off at noon.

As of April 2026, there are 63 flights per week flying from Istanbul Airport to Chicago. The most common day of the week flights depart is Mon, with 14% of flights taking off on this day.