What is the cheapest airline that flies from Indiana to South America?

Spirit Airlines, Copa Airlines, and Avianca are the most popular carriers operating from Indiana to South America

How many flights depart from Indiana to South America on average per week?

The number of flights available between Indiana and South America is 28 per week as of September 2025. The most frequent departure day is Mon, with 14% of weekly flights leaving on this day.

How long is the flight from Indiana to South America?

Average flight duration from Indiana to South America depends on which airport you fly into and out of. Flying from Indianapolis to Copenhagen is 14h 22m on average, while flying from South Bend to Copenhagen is 16h 39m on average. Copenhagen is the most popular airport in South America.

What airlines fly to South America?

Delta, American Airlines and Spirit Airlines are the top three most popular airlines that fly to South America from Indiana according to our data. Delta is the first choice among our users, with 33% of people opting to fly with this airline when traveling to South America. Keep in mind that there are 5 different airlines that fly to South America on a routine basis, so you have a few additional options to choose from.

When did momondo last update prices for flights from Indiana to South America?

Prices for flights from Indiana to South America are updated daily.

How many operators does momondo search for flights from Indiana to South America?

As of September 2025, there are 12 operators available to choose from for flights from Indiana to South America.

How old do you have to be to fly from Indiana to South America?

The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Indiana to South America.

What documentation or ID do you need to fly to South America?

The travel and health documents required for your trip to South America can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at South America. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

$91 Cheap Flights from Indiana to South America in 2025

1 adult

0 bags

Discover deals from 900+ travel sites with momondo.

Save money when you book flights with momondo

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Not ready to book? to track prices.

Search flight deals

Find the cheapest flights from Indiana to South America

Round-trip

One-way

Last minute

Direct

Cheap round-trip flights

5:05 am - 12:25 pmORD-CTG

7h 20m1 stop

1:32 pm - 11:45 pmCTG-ORD

10h 13m1 stop

$287Spirit Airlines

Find Deal

Sun, Oct 5 - Sat, Oct 11

5:05 am - 12:25 pmORD-CTG

7h 20m1 stop

1:32 pm - 11:45 pmCTG-ORD

10h 13m1 stop

$289Spirit Airlines

Find Deal

Sun, Oct 5 - Sat, Oct 11

3:07 pm - 8:42 amORD-CTG

17h 35m1 stop

9:27 am - 12:56 amCTG-ORD

15h 29m1 stop

$290Copa Airlines

Find Deal

Fri, Oct 24 - Mon, Oct 27

10:20 pm - 11:40 amORD-CTG

12h 20m1 stop

8:25 am - 9:20 pmCTG-ORD

12h 55m1 stop

$296Avianca

Find Deal

Thu, Mar 5 - Tue, Mar 10

8:02 am - 11:00 pmORD-CTG

14h 58m1 stop

9:42 am - 12:21 amCTG-ORD

14h 39m1 stop

$305Copa Airlines

Find Deal

Sun, Sep 21 - Wed, Oct 1

9:02 pm - 1:26 pmORD-CTG

15h 24m2 stops

4:30 pm - 9:05 amCTG-ORD

17h 35m2 stops

$306American Airlines

Find Deal

Sat, Nov 8 - Tue, Nov 11

4:40 pm - 1:26 pmORD-CTG

19h 46m1 stop

4:30 pm - 9:05 amCTG-ORD

17h 35m2 stops

$314American Airlines

Find Deal

Mon, Nov 3 - Mon, Nov 10

10:20 pm - 11:40 amORD-CTG

12h 20m1 stop

7:15 am - 8:20 pmCTG-ORD

14h 05m1 stop

$326Avianca

Find Deal

Thu, Nov 13 - Thu, Nov 20

8:49 pm - 1:04 pmORD-MDE

16h 15m1 stop

1:16 am - 6:38 pmMDE-ORD

17h 22m1 stop

$332

Find Deal

Sun, Oct 5 - Tue, Oct 14

4:53 pm - 12:21 amORD-MDE

7h 28m1 stop

1:16 am - 3:08 pmMDE-ORD

13h 52m2 stops

$336

Find Deal

Mon, Oct 6 - Tue, Oct 14

Copa Airlines flights from Indiana to South America

Our best Copa Airlines deals on Indiana to South America flight tickets

Copa Airlines

Oct 24

ORD3:07 pmChicago O'Hare Intl

17h 35m

1 stop

CTG8:42 amCartagena Rafael Nunez

Oct 27

CTG9:27 amCartagena Rafael Nunez

15h 29m

1 stop

ORD12:56 amChicago O'Hare Intl

$290

Find similar

Copa Airlines

Sep 21

ORD8:02 amChicago O'Hare Intl

14h 58m

1 stop

CTG11:00 pmCartagena Rafael Nunez

Oct 1

CTG9:42 amCartagena Rafael Nunez

14h 39m

1 stop

ORD12:21 amChicago O'Hare Intl

$305

Find similar

Copa Airlines

Feb 9

ORD2:22 pmChicago O'Hare Intl

8h 43m

1 stop

BOG12:05 amBogotá El Dorado

Feb 23

BOG4:45 amBogotá El Dorado

8h 46m

1 stop

ORD12:31 pmChicago O'Hare Intl

$309

Find similar

Avianca flights from Indiana to South America

Our best Avianca deals on Indiana to South America flight tickets

Avianca

Mar 5

ORD10:20 pmChicago O'Hare Intl

12h 20m

1 stop

CTG11:40 amCartagena Rafael Nunez

Mar 10

CTG8:25 amCartagena Rafael Nunez

12h 55m

1 stop

ORD9:20 pmChicago O'Hare Intl

$296

Find similar

Avianca

Nov 13

ORD10:20 pmChicago O'Hare Intl

12h 20m

1 stop

CTG11:40 amCartagena Rafael Nunez

Nov 20

CTG7:15 amCartagena Rafael Nunez

14h 05m

1 stop

ORD8:20 pmChicago O'Hare Intl

$326

Find similar

Avianca

Jan 29

ORD10:20 pmChicago O'Hare Intl

16h 20m

1 stop

CTG3:40 pmCartagena Rafael Nunez

Feb 2

CTG8:30 pmCartagena Rafael Nunez

24h 50m

1 stop

ORD8:20 pmChicago O'Hare Intl

$336

Find similar

Fly from

Fly to

Route

Depart

Return

Price

ChicagoCartagena

ORD - CTG

ORDCTG

Chicago O'Hare Intl

Sun 10/5

5:05 am-12:25 pm

1 stop7h 20m

Cartagena Rafael Nunez

Sat 10/11

1:32 pm-11:45 pm

1 stop10h 13m

$287

ChicagoCartagena

ORD - CTG

ORDCTG

Chicago O'Hare Intl

Sun 10/5

5:05 am-12:25 pm

1 stop7h 20m

Cartagena Rafael Nunez

Sat 10/11

1:32 pm-11:45 pm

1 stop10h 13m

$289

ChicagoCartagena

ORD - CTG

ORDCTG

Chicago O'Hare Intl

Fri 10/24

3:07 pm-8:42 am

1 stop17h 35m

Cartagena Rafael Nunez

Mon 10/27

9:27 am-12:56 am

1 stop15h 29m

$290

ChicagoCartagena

ORD - CTG

ORDCTG

Chicago O'Hare Intl

Thu 3/5

10:20 pm-11:40 am

1 stop12h 20m

Cartagena Rafael Nunez

Tue 3/10

8:25 am-9:20 pm

1 stop12h 55m

$296

ChicagoCartagena

ORD - CTG

ORDCTG

Chicago O'Hare Intl

Sun 9/21

8:02 am-11:00 pm

1 stop14h 58m

Cartagena Rafael Nunez

Wed 10/1

9:42 am-12:21 am

1 stop14h 39m

$305

ChicagoCartagena

ORD - CTG

ORDCTG

Chicago O'Hare Intl

Sat 11/8

9:02 pm-1:26 pm

2 stops15h 24m

Cartagena Rafael Nunez

Tue 11/11

4:30 pm-9:05 am

2 stops17h 35m

$306

ChicagoCartagena

ORD - CTG

ORDCTG

Chicago O'Hare Intl

Mon 11/3

4:40 pm-1:26 pm

1 stop19h 46m

Cartagena Rafael Nunez

Mon 11/10

4:30 pm-9:05 am

2 stops17h 35m

$314

ChicagoCartagena

ORD - CTG

ORDCTG

Chicago O'Hare Intl

Thu 11/13

10:20 pm-11:40 am

1 stop12h 20m

Cartagena Rafael Nunez

Thu 11/20

7:15 am-8:20 pm

1 stop14h 05m

$326

ChicagoMedellín

ORD - MDE

ORDMDE

Chicago O'Hare Intl

Sun 10/5

8:49 pm-1:04 pm

1 stop16h 15m

Medellín Jose Maria Cordova Intl

Tue 10/14

1:16 am-6:38 pm

1 stop17h 22m

$332

ChicagoMedellín

ORD - MDE

ORDMDE

Chicago O'Hare Intl

Mon 10/6

4:53 pm-12:21 am

1 stop7h 28m

Medellín Jose Maria Cordova Intl

Tue 10/14

1:16 am-3:08 pm

2 stops13h 52m

$336

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Indiana to South America

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Other information

What is the cheapest month to fly to South America?

In general, January is the cheapest month to fly from Indiana to South America. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $663. If you aren’t able to travel during the month of January, then book flights to South America from Indiana during May instead. Flights to South America in May, while not as cheap as those in January, still average around $754.

What is the cheapest day to depart on your flight to South America?

The cheapest day to depart from Indiana to South America is on a Tuesday when prices can be found for as low as $690. When flying out on a Friday, the most expensive travel day of the week, you can expect to see flight prices from Indiana to South America for around $873.

What is the cheapest time of day to depart on your flight to South America?

Our data shows that the cheapest Indiana to South America flights are usually those with departure times in the afternoon. Our users have found flights to South America in the afternoon for as low as $783. If you have a flexible travel schedule, then try to avoid flying in the morning when prices are $812 on average. Flights to South America from Indiana in the morning are generally more expensive because this time of day is more convenient for travelers’ schedules.

How far in advance should I book a flight to South America?

You are more likely to see cheaper flights to South America from Indiana when booking weeks ahead of your departure date. In general, you can expect to find flights to South America for around $827 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to South America from Indiana for as low as $673 on momondo.

Can stopping save me money on Indiana to South America flights?

You could potentially save up to 70% on your flight if you consider stops on a Indiana to South America flight.

Cheap Indiana to South America flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Indiana to South America

Fastest flight time	5h 50m
Direct flights	Every day
Airports in South America	1 airport

The fastest flight from Indiana to South America takes 5h 50m

Direct flights go from Indiana to South America every day.

There is 1 airport near South America: Bogotá El Dorado (BOG)

Search flight deals

When did momondo last update prices for flights from Indiana to South America?
Prices for flights from Indiana to South America are updated daily.
How many operators does momondo search for flights from Indiana to South America?
As of September 2025, there are 12 operators available to choose from for flights from Indiana to South America.
How old do you have to be to fly from Indiana to South America?
The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Indiana to South America.
What documentation or ID do you need to fly to South America?
The travel and health documents required for your trip to South America can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at South America. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Best airlines flying from Indiana to South America

Compare and see reviews for airlines that fly from Indiana to South America with momondo

Airline	Rating	Free Cancellation	Price
Spirit Airlines	PriceFrom $288	Free Cancellation	Rating 6.3 8,023 reviews	Search Spirit Airlines flights
LATAM Airlines	PriceFrom $426	Free Cancellation	Rating 7.5 1,847 reviews	Search LATAM Airlines flights
Delta	PriceFrom $426	Free Cancellation	Rating 7.9 7,960 reviews	Search Delta flights
American Airlines	PriceFrom $495	Free Cancellation	Rating 7.2 10,000 reviews	Search American Airlines flights
United Airlines	PriceFrom $538	Free Cancellation	Rating 7.4 8,937 reviews	Search United Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Indiana to South America?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Indiana to South America for you.

Can I find flights from Indiana to South America with flexible booking policies on momondo?

All flight searches from Indiana to South America on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Indiana to South America?

Once all potential Indiana to South America flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Indiana to South America right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Indiana to South America flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

An easier way to manage your South America trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Start using Trips

Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

1 adult

Sat 10/11

Sat 10/18

Email me momondo's favorite deals

By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to South America

Popular cities in South America

Flights to Limafrom $276

Flights to Buenos Airesfrom $557

Flights to Bogotáfrom $180

Flights to Sao Paulofrom $331

Flights to Medellínfrom $173

Flights to Rio de Janeirofrom $387

Flights to Santiagofrom $362

Flights to Cartagenafrom $181

Flights to Quitofrom $303

Flights to Cuscofrom $378

Flights to Califrom $195

Flights to Guayaquilfrom $231

Cheap flights from Indiana to South America from $91

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Indiana to South America departing on 9/30. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.

Big names and deals

Big names and deals

Filter for what you want

Filter for what you want

Trusted and free

Trusted and free

Price Alerts

Price Alerts

Find the cheapest flights from Indiana to South America

Cheap round-trip flights

Cheap one-way flights

Cheap last minute flights

Cheap direct flights

Copa Airlines flights from Indiana to South America

Our best Copa Airlines deals on Indiana to South America flight tickets

Avianca flights from Indiana to South America

Our best Avianca deals on Indiana to South America flight tickets

momondo Fare Finder

Use the filters below to find and compare flights from Indiana to South America that are best for you.

How to get the cheapest flight ticket from Indiana to South America

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to South America?

What is the cheapest day to depart on your flight to South America?

The cheapest day to depart from Indiana to South America is on a Tuesday when prices can be found for as low as $690. When flying out on a Friday, the most expensive travel day of the week, you can expect to see flight prices from Indiana to South America for around $873.

What is the cheapest time of day to depart on your flight to South America?

How far in advance should I book a flight to South America?

Can stopping save me money on Indiana to South America flights?

You could potentially save up to 70% on your flight if you consider stops on a Indiana to South America flight.

What is the cheapest airline that flies from Indiana to South America?

Spirit Airlines, Copa Airlines, and Avianca are the most popular carriers operating from Indiana to South America

What airlines fly to South America?

How many flights depart from Indiana to South America on average per week?

The number of flights available between Indiana and South America is 28 per week as of September 2025. The most frequent departure day is Mon, with 14% of weekly flights leaving on this day.

How long is the flight from Indiana to South America?

Average flight duration from Indiana to South America depends on which airport you fly into and out of. Flying from Indianapolis to Copenhagen is 14h 22m on average, while flying from South Bend to Copenhagen is 16h 39m on average. Copenhagen is the most popular airport in South America.

Cheap Indiana to South America flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Indiana to South America

Fastest flight time

Direct flights

Airports in South America

When did momondo last update prices for flights from Indiana to South America?

How many operators does momondo search for flights from Indiana to South America?

How old do you have to be to fly from Indiana to South America?

What documentation or ID do you need to fly to South America?

Best airlines flying from Indiana to South America

Compare and see reviews for airlines that fly from Indiana to South America with momondo

Why use momondo?

Why should I use momondo to find a flight deal from Indiana to South America?

Can I find flights from Indiana to South America with flexible booking policies on momondo?

How can momondo help me find flights from Indiana to South America?

I’m not ready to book a flight from Indiana to South America right now. Can momondo alert me if prices change?

An easier way to manage your South America trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

Find better results for your trip to South America

Popular cities in South America

Popular flights according to clicks in the last 7 days on momondo