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Cheap flights from Indiana to Des Moines from $73

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Indiana to Des Moines departing on 9/17. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Indiana to Des Moines

Cheap round-trip flights

Southwest Logo
7:00 am - 2:40 pmORD-DSM
7h 40m1 stop
Southwest Logo
6:35 am - 2:00 pmDSM-ORD
7h 25m1 stop
$163Southwest
Find Deal
Wed, Oct 1 - Mon, Oct 27
Southwest Logo
5:45 am - 9:30 amMDW-DSM
3h 45m1 stop
Southwest Logo
4:45 pm - 10:05 pmDSM-MDW
5h 20m1 stop
$166Southwest
Find Deal
Tue, Oct 14 - Wed, Oct 15
Delta Logo
6:15 am - 10:14 amORD-DSM
3h 59m1 stop
Delta Logo
5:25 pm - 9:21 pmDSM-ORD
3h 56m1 stop
$177Delta
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Sat, Sep 20 - Mon, Sep 22
Frontier Logo
6:00 am - 2:23 pmORD-DSM
8h 23m1 stop
Frontier Logo
3:23 pm - 12:32 amDSM-ORD
9h 09m1 stop
$182Frontier
Find Deal
Thu, Aug 28 - Sun, Aug 31
American Airlines Logo
10:06 pm - 11:24 pmORD-DSM
1h 18mnonstop
American Airlines Logo
9:28 am - 10:58 amDSM-ORD
1h 30mnonstop
$189American Airlines
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Thu, Aug 28 - Sun, Aug 31
American Airlines Logo
3:18 pm - 4:44 pmORD-DSM
1h 26mnonstop
American Airlines Logo
3:21 pm - 4:54 pmDSM-ORD
1h 33mnonstop
$190American Airlines
Find Deal
Thu, Aug 28 - Sun, Aug 31
United Airlines Logo
11:20 am - 2:10 pmIND-DSM
3h 50m1 stop
United Airlines Logo
8:00 am - 1:17 pmDSM-IND
4h 17m1 stop
$191United Airlines
Find Deal
Tue, Aug 26 - Wed, Aug 27
Frontier Logo
6:00 am - 2:23 pmORD-DSM
8h 23m1 stop
Frontier Logo
3:23 pm - 12:32 amDSM-ORD
9h 09m1 stop
$198Frontier
Find Deal
Thu, Aug 28 - Sun, Aug 31
Delta Logo
6:10 am - 10:07 amORD-DSM
3h 57m1 stop
Delta Logo
3:30 pm - 9:35 pmDSM-ORD
6h 05m1 stop
$218Delta
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Thu, Aug 28 - Sat, Aug 30
United Airlines Logo
9:12 am - 10:39 amORD-DSM
1h 27mnonstop
United Airlines Logo
9:44 pm - 11:15 pmDSM-ORD
1h 31mnonstop
$254United Airlines
Find Deal
Fri, Aug 22 - Sun, Nov 30

American Airlines flights from Indiana to Des Moines

Our best American Airlines deals on Indiana to Des Moines flight tickets
American Airlines
Aug 28
ORD10:06 pmChicago O'Hare Intl
1h 18m
DSM11:24 pmDes Moines
Aug 31
DSM9:28 amDes Moines
1h 30m
ORD10:58 amChicago O'Hare Intl
$189
Find similar
American Airlines
Aug 28
ORD3:18 pmChicago O'Hare Intl
1h 26m
DSM4:44 pmDes Moines
Aug 31
DSM3:21 pmDes Moines
1h 33m
ORD4:54 pmChicago O'Hare Intl
$190
Find similar
American Airlines
Aug 30
SDF4:51 pmLouisville Intl
7h 26m
1 stop
DSM11:17 pmDes Moines
Sep 1
DSM3:21 pmDes Moines
6h 52m
1 stop
SDF11:13 pmLouisville Intl
$191
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Delta flights from Indiana to Des Moines

Our best Delta deals on Indiana to Des Moines flight tickets
Delta
Sep 20
ORD6:15 amChicago O'Hare Intl
3h 59m
1 stop
DSM10:14 amDes Moines
Sep 22
DSM5:25 pmDes Moines
3h 56m
1 stop
ORD9:21 pmChicago O'Hare Intl
$177
Find similar
Delta
Aug 28
ORD6:10 amChicago O'Hare Intl
3h 57m
1 stop
DSM10:07 amDes Moines
Aug 30
DSM3:30 pmDes Moines
6h 05m
1 stop
ORD9:35 pmChicago O'Hare Intl
$218
Find similar
Delta
Oct 31
MDW9:20 amChicago Midway
4h 39m
1 stop
DSM1:59 pmDes Moines
Nov 2
DSM5:05 amDes Moines
6h 23m
1 stop
MDW11:28 amChicago Midway
$223
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Indiana to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 7, 2025.
Use the filters below to find and compare flights from Indiana to Des Moines that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

ChicagoDes Moines

ORD - DSM

ORDDSM

Chicago O'Hare Intl

Wed 10/1

7:00 am-2:40 pm

1 stop7h 40m

Des Moines

Mon 10/27

6:35 am-2:00 pm

1 stop7h 25m

$163

ChicagoDes Moines

MDW - DSM

MDWDSM

Chicago Midway

Tue 10/14

5:45 am-9:30 am

1 stop3h 45m

Des Moines

Wed 10/15

4:45 pm-10:05 pm

1 stop5h 20m

$166

ChicagoDes Moines

ORD - DSM

ORDDSM

Chicago O'Hare Intl

Sat 9/20

6:15 am-10:14 am

1 stop3h 59m

Des Moines

Mon 9/22

5:25 pm-9:21 pm

1 stop3h 56m

$177

ChicagoDes Moines

ORD - DSM

ORDDSM

Chicago O'Hare Intl

Thu 8/28

6:00 am-2:23 pm

1 stop8h 23m

Des Moines

Sun 8/31

3:23 pm-12:32 am

1 stop9h 09m

$182

ChicagoDes Moines

ORD - DSM

ORDDSM

Chicago O'Hare Intl

Thu 8/28

10:06 pm-11:24 pm

Nonstop1h 18m

Des Moines

Sun 8/31

9:28 am-10:58 am

Nonstop1h 30m

$189

ChicagoDes Moines

ORD - DSM

ORDDSM

Chicago O'Hare Intl

Thu 8/28

3:18 pm-4:44 pm

Nonstop1h 26m

Des Moines

Sun 8/31

3:21 pm-4:54 pm

Nonstop1h 33m

$190

IndianapolisDes Moines

IND - DSM

INDDSM

Indianapolis

Tue 8/26

11:20 am-2:10 pm

1 stop3h 50m

Des Moines

Wed 8/27

8:00 am-1:17 pm

1 stop4h 17m

$191

ChicagoDes Moines

ORD - DSM

ORDDSM

Chicago O'Hare Intl

Thu 8/28

6:00 am-2:23 pm

1 stop8h 23m

Des Moines

Sun 8/31

3:23 pm-12:32 am

1 stop9h 09m

$198

ChicagoDes Moines

ORD - DSM

ORDDSM

Chicago O'Hare Intl

Thu 8/28

6:10 am-10:07 am

1 stop3h 57m

Des Moines

Sat 8/30

3:30 pm-9:35 pm

1 stop6h 05m

$218

ChicagoDes Moines

ORD - DSM

ORDDSM

Chicago O'Hare Intl

Fri 8/22

9:12 am-10:39 am

Nonstop1h 27m

Des Moines

Sun 11/30

9:44 pm-11:15 pm

Nonstop1h 31m

$254

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Des Moines from

How to get the cheapest flight ticket from Indiana to Des Moines

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Des Moines?

If you’re not able to fly to Des Moines in January, then May is your next best option. Flight prices from Indiana to Des Moines during May average around $352.

What is the cheapest day to depart on your flight to Des Moines?

The cheapest day to depart from Indiana to Des Moines is on a Tuesday. Travelers who choose to depart for Des Moines on a Tuesday will often find tickets for as low as $299. Flights from Indiana to Des Moines on a Monday will generally be more expensive and average around $539. Keep in mind that these prices on both days could fluctuate depending on the season and the demand.

What is the cheapest time of day to depart on your flight to Des Moines?

According to our data, the cheapest time of day to fly to Des Moines is in the morning. momondo users have found flights departing from Indiana to Des Moines in the morning for as low as $376. Keep in mind that these prices may fluctuate based on what airline you choose and the time of year you plan to travel. Try not to purchase tickets at noon because they tend to be around $450. Of course, these prices can vary depending on the time of year and what airport you fly to.

Cheap Indiana to Des Moines flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Indiana to Des Moines

Best Price Found

$73

Fastest flight time

1h 18m

Direct flights

Every day

Airports in Des Moines

1 airport
The best one-way flight to Des Moines from Indiana in the past 72 hours is $73. The best round-trip flight deal from Indiana to Des Moines found on momondo in the last 72 hours is $163.
The fastest flight from Indiana to Des Moines takes 1h 18m
Direct flights go from Indiana to Des Moines every day.
There is 1 airport near Des Moines: Des Moines (DSM)
Search flight deals

  • When did momondo last update prices for flights from Indiana to Des Moines Airport?

    Prices for flights from Indiana to Des Moines Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Indiana to Des Moines Airport?

  • How old do you have to be to fly from Indiana to Des Moines Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Indiana to Des Moines Airport.

  • What documentation or ID do you need to fly to Des Moines Airport?

    The required travel and health documents for your Des Moines Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Des Moines Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from Indiana to Des Moines

Compare and see reviews for airlines that fly from Indiana to Des Moines with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $228Free CancellationRating
8.0
7,985 reviews
Search Delta flights
United AirlinesPriceFrom $241Free CancellationRating
7.4
8,917 reviews
Search United Airlines flights
American AirlinesPriceFrom $246Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
West Des Moines
Ames
Ankeny
Altoona
Clive
Urbandale
Newton
Pella
Boone
Johnston
Osceola
Norwalk
Grinnell
Oskaloosa
Carlisle

Why use momondo?

Why should I use momondo to find a flight deal from Indiana to Des Moines?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Indiana to Des Moines. momondo saves you time and could save you money on your trip.

Can I find flights from Indiana to Des Moines with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Des Moines from Indiana with this policy.

How can momondo help me find flights from Indiana to Des Moines?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Indiana to Des Moines.

I’m not ready to book a flight from Indiana to Des Moines right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Des Moines from Indiana. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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