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Cheap flights from Greenville to South America from $180

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Greenville to South America departing on 10/31. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Greenville to South America

Cheap round-trip flights

Multiple Airlines Logo
8:03 pm - 1:55 pmGSP-MDE
17h 52m1 stop
Multiple Airlines Logo
2:54 pm - 2:46 pmMDE-GSP
23h 52m1 stop
$402Multiple Airlines
Find Deal
Fri, Nov 7 - Wed, Nov 12
Multiple Airlines Logo
3:38 pm - 1:15 pmGSP-BOG
22h 37m2 stops
Multiple Airlines Logo
12:55 pm - 2:47 pmBOG-GSP
24h 52m1 stop
$422Multiple Airlines
Find Deal
Sat, Oct 18 - Sat, Oct 25
United Airlines Logo
9:10 am - 11:05 pmGSP-BOG
13h 55m2 stops
United Airlines Logo
8:15 am - 9:59 pmBOG-GSP
13h 44m1 stop
$518United Airlines
Find Deal
Tue, Nov 4 - Tue, Nov 11
Delta Logo
7:05 am - 2:25 pmGSP-BOG
7h 20m1 stop
Delta Logo
6:15 am - 10:34 pmBOG-GSP
16h 19m2 stops
$520Delta
Find Deal
Sat, Nov 8 - Thu, Nov 13
American Airlines Logo
5:00 am - 1:26 pmGSP-CTG
8h 26m1 stop
American Airlines Logo
4:30 pm - 11:59 pmCTG-GSP
7h 29m1 stop
$522American Airlines
Find Deal
Tue, Nov 4 - Tue, Nov 11
United Airlines Logo
9:10 am - 5:10 amGSP-BOG
20h 00m2 stops
United Airlines Logo
8:15 am - 11:49 amBOG-GSP
27h 34m2 stops
$522United Airlines
Find Deal
Tue, Nov 4 - Tue, Nov 11
American Airlines Logo
6:19 pm - 1:26 pmGSP-CTG
19h 07m2 stops
American Airlines Logo
4:30 pm - 9:39 amCTG-GSP
17h 09m2 stops
$526American Airlines
Find Deal
Tue, Nov 4 - Tue, Nov 11
Delta Logo
6:45 am - 6:40 pmGSP-BOG
12h 55m2 stops
Delta Logo
7:00 am - 9:22 pmBOG-GSP
13h 22m2 stops
$542Delta
Find Deal
Wed, Mar 11 - Fri, Mar 13
LATAM Airlines Logo
7:45 am - 2:30 pmGSP-BOG
6h 45m1 stop
LATAM Airlines Logo
3:55 pm - 9:03 amBOG-GSP
17h 08m1 stop
$571LATAM Airlines
Find Deal
Sun, Nov 16 - Mon, Dec 1
LATAM Airlines Logo
7:45 am - 8:20 pmGSP-BOG
12h 35m2 stops
LATAM Airlines Logo
7:00 am - 10:34 pmBOG-GSP
15h 34m2 stops
$575LATAM Airlines
Find Deal
Sun, Nov 16 - Mon, Dec 1

United Airlines flights from Greenville to South America

Our best United Airlines deals on Greenville to South America flight tickets
United Airlines
Nov 4
GSP9:10 amGreenville
13h 55m
2 stops
BOG11:05 pmBogotá El Dorado
Nov 11
BOG8:15 amBogotá El Dorado
13h 44m
1 stop
GSP9:59 pmGreenville
$518
Find similar
United Airlines
Nov 4
GSP9:10 amGreenville
20h 00m
2 stops
BOG5:10 amBogotá El Dorado
Nov 11
BOG8:15 amBogotá El Dorado
27h 34m
2 stops
GSP11:49 amGreenville
$522
Find similar
United Airlines
Nov 4
GSP4:56 pmGreenville
12h 14m
1 stop
BOG5:10 amBogotá El Dorado
Nov 10
BOG1:30 amBogotá El Dorado
20h 29m
1 stop
GSP9:59 pmGreenville
$527
Find similar

Delta flights from Greenville to South America

Our best Delta deals on Greenville to South America flight tickets
Delta
Nov 8
GSP7:05 amGreenville
7h 20m
1 stop
BOG2:25 pmBogotá El Dorado
Nov 13
BOG6:15 amBogotá El Dorado
16h 19m
2 stops
GSP10:34 pmGreenville
$520
Find similar
Delta
Mar 11
GSP6:45 amGreenville
12h 55m
2 stops
BOG6:40 pmBogotá El Dorado
Mar 13
BOG7:00 amBogotá El Dorado
13h 22m
2 stops
GSP9:22 pmGreenville
$542
Find similar
Delta
Nov 4
GSP6:35 amGreenville
16h 41m
2 stops
CTG11:16 pmCartagena Rafael Nunez
Nov 10
CTG4:35 amCartagena Rafael Nunez
14h 38m
2 stops
GSP7:13 pmGreenville
$548
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Greenville to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated September 21, 2025.
Use the filters below to find and compare flights from Greenville to South America that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

GreenvilleMedellín

GSP - MDE

GSPMDE

Greenville

Fri 11/7

8:03 pm-1:55 pm

1 stop17h 52m

Medellín Jose Maria Cordova Intl

Wed 11/12

2:54 pm-2:46 pm

1 stop23h 52m

$402

GreenvilleBogotá

GSP - BOG

GSPBOG

Greenville

Sat 10/18

3:38 pm-1:15 pm

2 stops22h 37m

Bogotá El Dorado

Sat 10/25

12:55 pm-2:47 pm

1 stop24h 52m

$422

GreenvilleBogotá

GSP - BOG

GSPBOG

Greenville

Tue 11/4

9:10 am-11:05 pm

2 stops13h 55m

Bogotá El Dorado

Tue 11/11

8:15 am-9:59 pm

1 stop13h 44m

$518

GreenvilleBogotá

GSP - BOG

GSPBOG

Greenville

Sat 11/8

7:05 am-2:25 pm

1 stop7h 20m

Bogotá El Dorado

Thu 11/13

6:15 am-10:34 pm

2 stops16h 19m

$520

GreenvilleCartagena

GSP - CTG

GSPCTG

Greenville

Tue 11/4

5:00 am-1:26 pm

1 stop8h 26m

Cartagena Rafael Nunez

Tue 11/11

4:30 pm-11:59 pm

1 stop7h 29m

$522

GreenvilleBogotá

GSP - BOG

GSPBOG

Greenville

Tue 11/4

9:10 am-5:10 am

2 stops20h 00m

Bogotá El Dorado

Tue 11/11

8:15 am-11:49 am

2 stops27h 34m

$522

GreenvilleCartagena

GSP - CTG

GSPCTG

Greenville

Tue 11/4

6:19 pm-1:26 pm

2 stops19h 07m

Cartagena Rafael Nunez

Tue 11/11

4:30 pm-9:39 am

2 stops17h 09m

$526

GreenvilleBogotá

GSP - BOG

GSPBOG

Greenville

Wed 3/11

6:45 am-6:40 pm

2 stops12h 55m

Bogotá El Dorado

Fri 3/13

7:00 am-9:22 pm

2 stops13h 22m

$542

GreenvilleBogotá

GSP - BOG

GSPBOG

Greenville

Sun 11/16

7:45 am-2:30 pm

1 stop6h 45m

Bogotá El Dorado

Mon 12/1

3:55 pm-9:03 am

1 stop17h 08m

$571

GreenvilleBogotá

GSP - BOG

GSPBOG

Greenville

Sun 11/16

7:45 am-8:20 pm

2 stops12h 35m

Bogotá El Dorado

Mon 12/1

7:00 am-10:34 pm

2 stops15h 34m

$575

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Greenville to South America

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to South America?

In general, November is the cheapest month to fly from Greenville to South America. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $621. If you aren’t able to travel during the month of November, then book flights to South America from Greenville during January instead. Flights to South America in January, while not as cheap as those in November, still average around $624.

What is the cheapest day to depart on your flight to South America?

The cheapest day to depart from Greenville to South America is on a Wednesday when prices can be found for as low as $713. When flying out on a Monday, the most expensive travel day of the week, you can expect to see flight prices from Greenville to South America for around $948.

What is the cheapest time of day to depart on your flight to South America?

Our data shows that the cheapest Greenville to South America flights are usually those with departure times in the afternoon. Our users have found flights to South America in the afternoon for as low as $734. If you have a flexible travel schedule, then try to avoid flying in the morning when prices are $785 on average. Flights to South America from Greenville in the morning are generally more expensive because this time of day is more convenient for travelers’ schedules.

Can stopping save me money on Greenville to South America flights?

You could potentially save up to 7% on your flight if you consider stops on a Greenville to South America flight.

Cheap Greenville to South America flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Greenville to South America

Direct flights

None
There are no direct flights from Greenville to South America. There are no popular flight routes from Greenville to South America.
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  • When did momondo last update prices for flights from Greenville Airport to South America?

    Prices for flights from Greenville Airport to South America were last updated today.

  • How many operators does momondo search for flights from Greenville Airport to South America?

  • How old do you have to be to fly from Greenville Airport to South America?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Greenville Airport to South America.

  • What documentation or ID do you need to fly to South America?

    The travel and health documents you'll need for your trip to South America may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at South America. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

Best airlines flying from Greenville to South America

Compare and see reviews for airlines that fly from Greenville to South America with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $490Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights
LATAM AirlinesPriceFrom $502Free CancellationRating
7.5
1,849 reviews
Search LATAM Airlines flights
DeltaPriceFrom $532Free CancellationRating
7.9
7,966 reviews
Search Delta flights

Why use momondo?

Why should I use momondo to find a flight deal from Greenville to South America?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Greenville to South America for you.

Can I find flights from Greenville to South America with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to South America from Greenville with this policy.

How can momondo help me find flights from Greenville to South America?

momondo provides multiple filters to help you find the best flight to South America from Greenville. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Greenville to South America right now. Can momondo alert me if prices change?

If you are simply researching potential flights to South America, momondo offers a useful price alert feature which will track prices for flights to South America from Greenville and alert you when they change.

An easier way to manage your South America trip

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Find better results for your trip to South America

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