What airlines fly to Panama?

American Airlines, Delta and United Airlines are the top three most popular airlines that fly to Panama from Greenville according to our data. American Airlines is the first choice among our users, with 45% of people opting to fly with this airline when traveling to Panama. Keep in mind that there are 3 different airlines that fly to Panama on a routine basis, so you have a few additional options to choose from.

What is the cheapest airline that flies from Greenville to Panama?

United Airlines, American Airlines, and Copa Airlines are the most popular carriers operating from Greenville to Panama

When did momondo last update prices for flights from Greenville Airport to Panama?

Prices for flights from Greenville Airport to Panama are refreshed on a daily basis.

How many operators does momondo search for flights from Greenville Airport to Panama?

There is 1 operator available for flights from Greenville Airport to Panama as of June 2026.

How old do you have to be to fly from Greenville Airport to Panama?

Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Greenville Airport to Panama.

What documentation or ID do you need to fly to Panama?

The travel and health documents you'll need for your trip to Panama may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Panama. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

$285 Cheap Flights from Greenville to Panama in 2026

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Greenville to Panama

Round-trip

One-way

Last minute

Cheap round-trip flights

Enter your travel dates to find the best prices.

5:46 am - 12:55 pm

GSP

PTY

8h 09m

1 stop

2:20 pm - 10:59 pm

PTY

GSP

7h 39m

1 stop

$557Delta

Tue, Aug 11 - Wed, Aug 19

5:43 pm - 2:14 pm

GSP

PTY

21h 31m

2 stops

3:30 pm - 1:32 pm

PTY

GSP

21h 02m

2 stops

$561United Airlines

Mon, Aug 17 - Thu, Aug 20

7:00 am - 6:37 pm

GSP

PTY

12h 37m

1 stop

3:30 pm - 4:50 pm

PTY

GSP

24h 20m

1 stop

$567United Airlines

Tue, Aug 11 - Wed, Aug 19

5:43 pm - 2:14 pm

GSP

PTY

21h 31m

2 stops

3:30 pm - 1:32 pm

PTY

GSP

21h 02m

2 stops

$571United Airlines

Tue, Aug 11 - Wed, Aug 19

7:47 pm - 7:31 pm

GSP

PTY

24h 44m

2 stops

3:30 pm - 9:58 pm

PTY

GSP

29h 28m

1 stop

$572United Airlines

Mon, Aug 17 - Thu, Aug 20

7:05 pm - 12:39 pm

GSP

PTY

18h 34m

2 stops

1:39 pm - 11:00 am

PTY

GSP

20h 21m

2 stops

$577American Airlines

Mon, Aug 17 - Tue, Aug 25

7:47 pm - 7:31 pm

GSP

PTY

24h 44m

2 stops

3:30 pm - 9:58 pm

PTY

GSP

29h 28m

1 stop

$582United Airlines

Mon, Aug 17 - Thu, Aug 20

7:00 am - 12:24 pm

GSP

PTY

6h 24m

1 stop

3:35 pm - 11:14 pm

PTY

GSP

6h 39m

1 stop

$583American Airlines

Tue, Sep 15 - Thu, Oct 15

6:40 pm - 12:39 pm

GSP

PTY

18h 59m

1 stop

1:39 pm - 11:00 am

PTY

GSP

20h 21m

2 stops

$588American Airlines

Mon, Aug 17 - Tue, Aug 25

11:18 am - 4:04 am

GSP

PTY

17h 46m

1 stop

10:55 pm - 10:37 am

PTY

GSP

10h 42m

1 stop

$591United Airlines

Mon, Jul 13 - Sun, Jul 19

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United Airlines flights from Greenville to Panama

Our best United Airlines deals on Greenville to Panama flight tickets

United Airlines

Aug 11

GSP5:43 pmGreenville

21h 31m

2 stops

PTY2:14 pmPanama City Tocumen Intl

Aug 19

PTY3:30 pmPanama City Tocumen Intl

21h 02m

2 stops

GSP1:32 pmGreenville

$561

United Airlines

Aug 11

GSP7:00 amGreenville

12h 37m

1 stop

PTY6:37 pmPanama City Tocumen Intl

Aug 19

PTY3:30 pmPanama City Tocumen Intl

24h 20m

1 stop

GSP4:50 pmGreenville

$567

United Airlines

Aug 11

GSP5:43 pmGreenville

21h 31m

2 stops

PTY2:14 pmPanama City Tocumen Intl

Aug 19

PTY3:30 pmPanama City Tocumen Intl

21h 02m

2 stops

GSP1:32 pmGreenville

$571

American Airlines flights from Greenville to Panama

Our best American Airlines deals on Greenville to Panama flight tickets

American Airlines

Sep 15

GSP7:00 amGreenville

6h 24m

1 stop

PTY12:24 pmPanama City Tocumen Intl

Oct 15

PTY3:35 pmPanama City Tocumen Intl

6h 39m

1 stop

GSP11:14 pmGreenville

$583

American Airlines

Jul 6

GSP6:18 pmGreenville

18h 56m

2 stops

PTY12:14 pmPanama City Tocumen Intl

Jul 13

PTY1:14 pmPanama City Tocumen Intl

22h 00m

2 stops

GSP12:14 pmGreenville

$621

American Airlines

Jul 6

GSP8:00 pmGreenville

17h 14m

1 stop

PTY12:14 pmPanama City Tocumen Intl

Jul 13

PTY1:14 pmPanama City Tocumen Intl

20h 47m

2 stops

GSP11:01 amGreenville

$633

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

GreenvillePanama City

GSP - PTY

GSPPTY

Greenville

Tue 8/11

5:46 am-12:55 pm

1 stop8h 09m

Panama City Tocumen Intl

Wed 8/19

2:20 pm-10:59 pm

1 stop7h 39m

$557

GreenvillePanama City

GSP - PTY

GSPPTY

Greenville

Mon 8/17

5:43 pm-2:14 pm

2 stops21h 31m

Panama City Tocumen Intl

Thu 8/20

3:30 pm-1:32 pm

2 stops21h 02m

$561

GreenvillePanama City

GSP - PTY

GSPPTY

Greenville

Tue 8/11

7:00 am-6:37 pm

1 stop12h 37m

Panama City Tocumen Intl

Wed 8/19

3:30 pm-4:50 pm

1 stop24h 20m

$567

GreenvillePanama City

GSP - PTY

GSPPTY

Greenville

Tue 8/11

5:43 pm-2:14 pm

2 stops21h 31m

Panama City Tocumen Intl

Wed 8/19

3:30 pm-1:32 pm

2 stops21h 02m

$571

GreenvillePanama City

GSP - PTY

GSPPTY

Greenville

Mon 8/17

7:47 pm-7:31 pm

2 stops24h 44m

Panama City Tocumen Intl

Thu 8/20

3:30 pm-9:58 pm

1 stop29h 28m

$572

GreenvillePanama City

GSP - PTY

GSPPTY

Greenville

Mon 8/17

7:05 pm-12:39 pm

2 stops18h 34m

Panama City Tocumen Intl

Tue 8/25

1:39 pm-11:00 am

2 stops20h 21m

$577

GreenvillePanama City

GSP - PTY

GSPPTY

Greenville

Mon 8/17

7:47 pm-7:31 pm

2 stops24h 44m

Panama City Tocumen Intl

Thu 8/20

3:30 pm-9:58 pm

1 stop29h 28m

$582

Quickest round-trip

GreenvillePanama City

GSP - PTY

GSPPTY

Greenville

Tue 9/15

7:00 am-12:24 pm

1 stop6h 24m

Panama City Tocumen Intl

Thu 10/15

3:35 pm-11:14 pm

1 stop6h 39m

$583

GreenvillePanama City

GSP - PTY

GSPPTY

Greenville

Mon 8/17

6:40 pm-12:39 pm

1 stop18h 59m

Panama City Tocumen Intl

Tue 8/25

1:39 pm-11:00 am

2 stops20h 21m

$588

GreenvillePanama City

GSP - PTY

GSPPTY

Greenville

Mon 7/13

11:18 am-4:04 am

1 stop17h 46m

Panama City Tocumen Intl

Sun 7/19

10:55 pm-10:37 am

1 stop10h 42m

$591

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Greenville to Panama

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the cheapest month to fly to Panama?

The month of September is, on average, the cheapest month to fly to Panama from Greenville, with most prices found around $0. If you don’t want to visit Panama in September, then you should wait until October to fly from Greenville, when ticket prices are also cheap, with an average price of $391.

Cheap Greenville to Panama flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Greenville to Panama

Fastest flight time	8h 09m
Direct flights	None

The fastest flight from Greenville to Panama takes 8h 09m

There are no direct flights from Greenville to Panama. There are no popular flight routes from Greenville to Panama.

Search flight deals

Frequently asked questions about flying from Greenville to Panama

When did momondo last update prices for flights from Greenville Airport to Panama?
Prices for flights from Greenville Airport to Panama are refreshed on a daily basis.
How many operators does momondo search for flights from Greenville Airport to Panama?
There is 1 operator available for flights from Greenville Airport to Panama as of June 2026.
How old do you have to be to fly from Greenville Airport to Panama?
Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Greenville Airport to Panama.
What documentation or ID do you need to fly to Panama?
The travel and health documents you'll need for your trip to Panama may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Panama. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

Best airlines flying from Greenville to Panama

Compare and see reviews for airlines that fly from Greenville to Panama with momondo

Airline	Rating	Free Cancellation	Price
American Airlines	PriceFrom $495	Free Cancellation	Rating 7.1 11,705 reviews		Search American Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Greenville to Panama?

It is quick and easy to find Greenville to Panama flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Panama that suits you.

Can I find flights from Greenville to Panama with flexible booking policies on momondo?

Yes. All flights to Panama from Greenville on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Greenville to Panama?

Once all potential Greenville to Panama flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Greenville to Panama right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Greenville to Panama now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Panama and let you know when they change.

An easier way to manage your Panama trip

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Popular cities in Panama

Flights to Panama Cityfrom $376

Flights to Bocas del Torofrom $678

Flights to Davidfrom $420

Flights to Changuinola

Cheap flights from Greenville to Panama from $285

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Greenville to Panama departing on 7/9. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.

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United Airlines flights from Greenville to Panama

Our best United Airlines deals on Greenville to Panama flight tickets

American Airlines flights from Greenville to Panama

Our best American Airlines deals on Greenville to Panama flight tickets

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How to get the cheapest flight ticket from Greenville to Panama

What is the cheapest month to fly to Panama?

What is the cheapest airline that flies from Greenville to Panama?

What airlines fly to Panama?

Cheap Greenville to Panama flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Greenville to Panama

Fastest flight time

Direct flights

Frequently asked questions about flying from Greenville to Panama

Best airlines flying from Greenville to Panama

Compare and see reviews for airlines that fly from Greenville to Panama with momondo

Why use momondo?

An easier way to manage your Panama trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

Find better results for your trip to Panama

Popular cities in Panama

Popular flights according to clicks in the last 7 days on momondo

Greenville flight routes

According to popular flight searches on momondo this year

Panama flight routes

According to popular flight searches on momondo this year

Fly your favorite airline to Panama

Airlines are sorted and displayed according to clicks in the past 7 days on momondo

Cabin classes currently available on flights to Panama

List of cabin classes available on flights landing in Panama. Availability may vary depending on flight origin and airline.

Complete your trip to Panama

Explore popular destinations other users love

According to popular flight searches on momondo this year