What is the cheapest airline that flies from Greenville to Panama?

United Airlines and Delta are the most popular carriers operating from Greenville to Panama

What airlines fly to Panama?

American Airlines, Delta and United Airlines are the top three most popular airlines that fly to Panama from Greenville according to our data. American Airlines is the first choice among our users, with 48% of people opting to fly with this airline when traveling to Panama. Keep in mind that there are 3 different airlines that fly to Panama on a routine basis, so you have a few additional options to choose from.

When did momondo last update prices for flights from Greenville Airport to Panama?

Prices for flights from Greenville Airport to Panama are refreshed on a daily basis.

How many operators does momondo search for flights from Greenville Airport to Panama?

There is 1 operator available for flights from Greenville Airport to Panama as of August 2026.

How old do you have to be to fly from Greenville Airport to Panama?

Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Greenville Airport to Panama.

What documentation or ID do you need to fly to Panama?

The travel and health documents you'll need for your trip to Panama may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Panama. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

$276 Cheap Flights from Greenville to Panama in 2026

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Greenville to Panama

Round-trip

One-way

Last minute

Cheap round-trip flights

Enter your travel dates to find the best prices.

5:30 am - 3:33 pmGSP Greenville-PTY Panama City Tocumen Intl

10h 03m1 stop Miami

2:27 pm - 11:57 pmPTY Panama City Tocumen Intl-GSP Greenville

9h 30m1 stop Miami

$627American Airlines

Tue, Jan 5 - Fri, Feb 5

5:00 am - 1:53 pmGSP Greenville-PTY Panama City Tocumen Intl

8h 53m1 stop Miami

2:27 pm - 11:57 pmPTY Panama City Tocumen Intl-GSP Greenville

9h 30m1 stop Miami

$627American Airlines

Tue, Jan 5 - Fri, Feb 5

7:00 am - 12:58 pmGSP Greenville-PTY Panama City Tocumen Intl

6h 58m1 stop Atlanta Hartsfield-Jackson

2:23 pm - 10:55 pmPTY Panama City Tocumen Intl-GSP Greenville

7h 32m1 stop Atlanta Hartsfield-Jackson

$627Delta

Wed, Sep 23 - Wed, Sep 30

7:00 am - 12:59 pmGSP Greenville-PTY Panama City Tocumen Intl

6h 59m1 stop Atlanta Hartsfield-Jackson

2:24 pm - 10:51 pmPTY Panama City Tocumen Intl-GSP Greenville

7h 27m1 stop Atlanta Hartsfield-Jackson

$627Delta

Tue, Oct 6 - Mon, Oct 12

7:00 am - 6:37 pmGSP Greenville-PTY Panama City Tocumen Intl

12h 37m1 stop Houston George Bush Intcntl

9:45 am - 11:13 pmPTY Panama City Tocumen Intl-GSP Greenville

12h 28m1 stop Newark

$627United Airlines

Tue, Oct 6 - Mon, Oct 12

6:00 am - 7:31 pmGSP Greenville-PTY Panama City Tocumen Intl

14h 31m1 stop Newark

3:30 pm - 1:33 pmPTY Panama City Tocumen Intl-GSP Greenville

21h 03m2 stops Houston George Bush Intcntl Chicago O'Hare Intl

$631United Airlines

Thu, Oct 1 - Mon, Oct 5

6:02 pm - 1:27 pmGSP Greenville-PTY Panama City Tocumen Intl

19h 25m2 stops Charlotte Douglas Miami

4:46 pm - 11:57 pmPTY Panama City Tocumen Intl-GSP Greenville

7h 11m1 stop Miami

$631American Airlines

Tue, Jan 5 - Fri, Feb 5

6:20 pm - 1:27 pmGSP Greenville-PTY Panama City Tocumen Intl

19h 07m2 stops Charlotte Douglas Miami

4:46 pm - 11:57 pmPTY Panama City Tocumen Intl-GSP Greenville

7h 11m1 stop Miami

$631American Airlines

Tue, Jan 5 - Fri, Feb 5

5:46 pm - 2:14 pmGSP Greenville-PTY Panama City Tocumen Intl

21h 28m2 stops Chicago O'Hare Intl Houston George Bush Intcntl

9:45 am - 11:13 pmPTY Panama City Tocumen Intl-GSP Greenville

12h 28m1 stop Newark

$631United Airlines

Tue, Oct 6 - Mon, Oct 12

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GOL flights from Greenville to Panama

Our best GOL deals on Greenville to Panama flight tickets

GOL

Jan 17

GSP7:00 amGreenville

8h 38m

1 stop

PTY3:38 pmPanama City Tocumen Intl

Jan 18

PTY4:46 pmPanama City Tocumen Intl

17h 47m

2 stops

GSP10:33 amGreenville

$799

GOL

Jan 17

GSP6:00 amGreenville

9h 38m

2 stops

PTY3:38 pmPanama City Tocumen Intl

Jan 18

PTY4:46 pmPanama City Tocumen Intl

17h 47m

2 stops

GSP10:33 amGreenville

$850

GOL

Aug 27

GSP7:05 pmGreenville

18h 34m

2 stops

PTY12:39 pmPanama City Tocumen Intl

Aug 31

PTY1:39 pmPanama City Tocumen Intl

20h 21m

2 stops

GSP11:00 amGreenville

$1,628

Delta flights from Greenville to Panama

Our best Delta deals on Greenville to Panama flight tickets

Delta

Sep 15

GSP7:00 amGreenville

6h 58m

1 stop

PTY12:58 pmPanama City Tocumen Intl

Oct 15

PTY2:24 pmPanama City Tocumen Intl

7h 27m

1 stop

GSP10:51 pmGreenville

$635

Delta

Aug 19

GSP6:55 amGreenville

7h 00m

1 stop

PTY12:55 pmPanama City Tocumen Intl

Aug 20

PTY2:20 pmPanama City Tocumen Intl

17h 58m

1 stop

GSP9:18 amGreenville

$752

Delta

Jan 17

GSP10:14 amGreenville

27h 41m

1 stop

PTY1:55 pmPanama City Tocumen Intl

Jan 20

PTY3:20 pmPanama City Tocumen Intl

8h 17m

1 stop

GSP11:37 pmGreenville

$763

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

GreenvillePanama City

GSP Greenville - PTY Panama City Tocumen Intl

GSPPTY

Greenville

Tue 1/5

5:30 am-3:33 pm

1 stop10h 03m

Panama City Tocumen Intl

Fri 2/5

2:27 pm-11:57 pm

1 stop9h 30m

$627

GreenvillePanama City

GSP Greenville - PTY Panama City Tocumen Intl

GSPPTY

Greenville

Tue 1/5

5:00 am-1:53 pm

1 stop8h 53m

Panama City Tocumen Intl

Fri 2/5

2:27 pm-11:57 pm

1 stop9h 30m

$627

GreenvillePanama City

GSP Greenville - PTY Panama City Tocumen Intl

GSPPTY

Greenville

Wed 9/23

7:00 am-12:58 pm

1 stop6h 58m

Panama City Tocumen Intl

Wed 9/30

2:23 pm-10:55 pm

1 stop7h 32m

$627

Quickest round-trip

GreenvillePanama City

GSP Greenville - PTY Panama City Tocumen Intl

GSPPTY

Greenville

Tue 10/6

7:00 am-12:59 pm

1 stop6h 59m

Panama City Tocumen Intl

Mon 10/12

2:24 pm-10:51 pm

1 stop7h 27m

$627

GreenvillePanama City

GSP Greenville - PTY Panama City Tocumen Intl

GSPPTY

Greenville

Tue 10/6

7:00 am-6:37 pm

1 stop12h 37m

Panama City Tocumen Intl

Mon 10/12

9:45 am-11:13 pm

1 stop12h 28m

$627

GreenvillePanama City

GSP Greenville - PTY Panama City Tocumen Intl

GSPPTY

Greenville

Thu 10/1

6:00 am-7:31 pm

1 stop14h 31m

Panama City Tocumen Intl

Mon 10/5

3:30 pm-1:33 pm

2 stops21h 03m

$631

GreenvillePanama City

GSP Greenville - PTY Panama City Tocumen Intl

GSPPTY

Greenville

Tue 1/5

6:02 pm-1:27 pm

2 stops19h 25m

Panama City Tocumen Intl

Fri 2/5

4:46 pm-11:57 pm

1 stop7h 11m

$631

GreenvillePanama City

GSP Greenville - PTY Panama City Tocumen Intl

GSPPTY

Greenville

Tue 1/5

6:20 pm-1:27 pm

2 stops19h 07m

Panama City Tocumen Intl

Fri 2/5

4:46 pm-11:57 pm

1 stop7h 11m

$631

GreenvillePanama City

GSP Greenville - PTY Panama City Tocumen Intl

GSPPTY

Greenville

Tue 10/6

5:46 pm-2:14 pm

2 stops21h 28m

Panama City Tocumen Intl

Mon 10/12

9:45 am-11:13 pm

1 stop12h 28m

$631

Cheapest one-way

GreenvillePanama City

GSP Greenville - PTY Panama City Tocumen Intl

GSPPTY

Greenville

Mon 9/28

6:00 am-7:31 pm

1 stop14h 31m

$276

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 19 resultsSorted by cheapest first

How to get the cheapest flight ticket from Greenville to Panama

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the cheapest month to fly to Panama?

The month of September is, on average, the cheapest month to fly to Panama from Greenville, with most prices found around $235. If you don’t want to visit Panama in September, then you should wait until February to fly from Greenville, when ticket prices are also cheap, with an average price of $485.

Cheap Greenville to Panama flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Greenville to Panama

Fastest flight time	8h 14m
Direct flights	None

The fastest flight from Greenville to Panama takes 8h 14m

There are no direct flights from Greenville to Panama. There are no popular flight routes from Greenville to Panama.

Search flight deals

Frequently asked questions about flying from Greenville to Panama

When did momondo last update prices for flights from Greenville Airport to Panama?
Prices for flights from Greenville Airport to Panama are refreshed on a daily basis.
How many operators does momondo search for flights from Greenville Airport to Panama?
There is 1 operator available for flights from Greenville Airport to Panama as of August 2026.
How old do you have to be to fly from Greenville Airport to Panama?
Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Greenville Airport to Panama.
What documentation or ID do you need to fly to Panama?
The travel and health documents you'll need for your trip to Panama may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Panama. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

Best airlines flying from Greenville to Panama

Compare and see reviews for airlines that fly from Greenville to Panama with momondo

Airline	Rating	Free Cancellation	Price
American Airlines	PriceFrom $495	Free Cancellation	Rating 7.1 11,893 reviews		Search American Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Greenville to Panama?

It is quick and easy to find Greenville to Panama flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Panama that suits you.

Can I find flights from Greenville to Panama with flexible booking policies on momondo?

Yes. All flights to Panama from Greenville on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Greenville to Panama?

Once all potential Greenville to Panama flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Greenville to Panama right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Greenville to Panama now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Panama and let you know when they change.

An easier way to manage your Panama trip

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Popular cities in Panama

Flights to Panama Cityfrom $453

Flights to Bocas del Torofrom $705

Flights to Davidfrom $406

Flights to Changuinola

Cheap flights from Greenville to Panama from $276

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Greenville to Panama departing on 9/28. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.

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GOL flights from Greenville to Panama

Our best GOL deals on Greenville to Panama flight tickets

Delta flights from Greenville to Panama

Our best Delta deals on Greenville to Panama flight tickets

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How to get the cheapest flight ticket from Greenville to Panama

What is the cheapest month to fly to Panama?

What is the cheapest airline that flies from Greenville to Panama?

What airlines fly to Panama?

Cheap Greenville to Panama flight deals and tips

Fastest flight time

Direct flights

Frequently asked questions about flying from Greenville to Panama

Best airlines flying from Greenville to Panama

Compare and see reviews for airlines that fly from Greenville to Panama with momondo

Why use momondo?

An easier way to manage your Panama trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

Find better results for your trip to Panama

Popular cities in Panama

Popular flights according to clicks in the last 7 days on momondo

Greenville flight routes

According to popular flight searches on momondo this year

Panama flight routes

According to popular flight searches on momondo this year

Fly your favorite airline to Panama

Airlines are sorted and displayed according to clicks in the past 7 days on momondo

Cabin classes currently available on flights to Panama

List of cabin classes available on flights landing in Panama. Availability may vary depending on flight origin and airline.

Complete your trip to Panama

Explore popular destinations other users love

According to popular flight searches on momondo this year