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Cheap flights from Detroit Metropolitan Wayne County Airport to Des Moines from $100

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Detroit Metropolitan Wayne County Airport to Des Moines departing on 1/29. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Detroit Metropolitan Wayne County Airport to Des Moines

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
6:45 am - 11:12 pmDTW-DSM
17h 27m1 stop
Multiple Airlines Logo
6:35 am - 7:44 amDSM-DTW
24h 09m1 stop
$197Multiple Airlines
Find Deal
Fri, Dec 5 - Mon, Dec 8
Multiple Airlines Logo
5:45 am - 6:38 pmDTW-DSM
13h 53m1 stop
Multiple Airlines Logo
8:00 am - 1:08 amDSM-DTW
16h 08m1 stop
$206Multiple Airlines
Find Deal
Fri, Nov 21 - Mon, Nov 24
Multiple Airlines Logo
6:15 am - 12:55 pmDTW-DSM
7h 40m1 stop
Multiple Airlines Logo
8:00 am - 1:08 amDSM-DTW
16h 08m1 stop
$208Multiple Airlines
Find Deal
Fri, Nov 21 - Mon, Nov 24
Southwest Logo
6:45 pm - 9:35 pmDTW-DSM
3h 50m1 stop
Southwest Logo
6:25 am - 4:05 pmDSM-DTW
8h 40m1 stop
$360Southwest
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Thu, Dec 11 - Sat, Dec 13
Southwest Logo
6:45 pm - 9:35 pmDTW-DSM
3h 50m1 stop
Southwest Logo
5:25 am - 7:50 pmDSM-DTW
13h 25m2 stops
$366Southwest
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Thu, Dec 11 - Sat, Dec 13
American Airlines Logo
5:57 pm - 11:35 pmDTW-DSM
6h 38m1 stop
American Airlines Logo
5:40 am - 8:00 pmDSM-DTW
13h 20m1 stop
$377American Airlines
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Fri, Dec 5 - Mon, Dec 8
American Airlines Logo
9:40 am - 11:44 pmDTW-DSM
15h 04m1 stop
American Airlines Logo
5:40 am - 8:00 pmDSM-DTW
13h 20m1 stop
$379American Airlines
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Tue, Dec 2 - Mon, Dec 8
Delta Logo
7:47 pm - 8:46 pmDTW-DSM
1h 59mnonstop
Delta Logo
6:17 am - 9:09 amDSM-DTW
1h 52mnonstop
$399Delta
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Thu, Dec 11 - Sat, Dec 13
Delta Logo
7:47 pm - 8:46 pmDTW-DSM
1h 59mnonstop
Delta Logo
3:30 pm - 10:36 pmDSM-DTW
6h 06m1 stop
$409Delta
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Thu, Dec 11 - Sat, Dec 13
United Airlines Logo
5:49 am - 10:50 amDTW-DSM
6h 01m1 stop
United Airlines Logo
11:15 am - 10:30 pmDSM-DTW
10h 15m1 stop
$442United Airlines
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Fri, Dec 19 - Thu, Dec 25

Southwest flights from Detroit Metropolitan Wayne County Airport to Des Moines

Our best Southwest deals on Detroit Metropolitan Wayne County Airport to Des Moines flight tickets
Southwest
Dec 11
DTW6:45 pmDetroit Metropolitan Wayne County
3h 50m
1 stop
DSM9:35 pmDes Moines
Dec 13
DSM6:25 amDes Moines
8h 40m
1 stop
DTW4:05 pmDetroit Metropolitan Wayne County
$360
Find similar
Southwest
Dec 11
DTW6:45 pmDetroit Metropolitan Wayne County
3h 50m
1 stop
DSM9:35 pmDes Moines
Dec 13
DSM5:25 amDes Moines
13h 25m
2 stops
DTW7:50 pmDetroit Metropolitan Wayne County
$366
Find similar
Southwest
Dec 5
DTW6:45 pmDetroit Metropolitan Wayne County
3h 50m
1 stop
DSM9:35 pmDes Moines
Dec 8
DSM6:15 amDes Moines
7h 30m
2 stops
DTW2:45 pmDetroit Metropolitan Wayne County
$402
Find similar

American Airlines flights from Detroit Metropolitan Wayne County Airport to Des Moines

Our best American Airlines deals on Detroit Metropolitan Wayne County Airport to Des Moines flight tickets
American Airlines
Dec 5
DTW5:57 pmDetroit Metropolitan Wayne County
6h 38m
1 stop
DSM11:35 pmDes Moines
Dec 8
DSM5:40 amDes Moines
13h 20m
1 stop
DTW8:00 pmDetroit Metropolitan Wayne County
$377
Find similar
American Airlines
Dec 2
DTW9:40 amDetroit Metropolitan Wayne County
15h 04m
1 stop
DSM11:44 pmDes Moines
Dec 8
DSM5:40 amDes Moines
13h 20m
1 stop
DTW8:00 pmDetroit Metropolitan Wayne County
$379
Find similar
American Airlines
Dec 1
DTW5:33 amDetroit Metropolitan Wayne County
3h 48m
1 stop
DSM8:21 amDes Moines
Dec 8
DSM8:50 amDes Moines
10h 10m
1 stop
DTW8:00 pmDetroit Metropolitan Wayne County
$404
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momondo Fare Finder

 
Customize your flight search to find flights from Detroit Metropolitan Wayne County Airport to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated November 4, 2025.
Use the filters below to find and compare flights from Detroit Metropolitan Wayne County Airport to Des Moines that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

DetroitDes Moines

DTW - DSM

DTWDSM

Detroit Metropolitan Wayne County

Fri 12/5

6:45 am-11:12 pm

1 stop17h 27m

Des Moines

Mon 12/8

6:35 am-7:44 am

1 stop24h 09m

$197

DetroitDes Moines

DTW - DSM

DTWDSM

Detroit Metropolitan Wayne County

Fri 11/21

5:45 am-6:38 pm

1 stop13h 53m

Des Moines

Mon 11/24

8:00 am-1:08 am

1 stop16h 08m

$206

DetroitDes Moines

DTW - DSM

DTWDSM

Detroit Metropolitan Wayne County

Fri 11/21

6:15 am-12:55 pm

1 stop7h 40m

Des Moines

Mon 11/24

8:00 am-1:08 am

1 stop16h 08m

$208

DetroitDes Moines

DTW - DSM

DTWDSM

Detroit Metropolitan Wayne County

Thu 12/11

6:45 pm-9:35 pm

1 stop3h 50m

Des Moines

Sat 12/13

6:25 am-4:05 pm

1 stop8h 40m

$360

DetroitDes Moines

DTW - DSM

DTWDSM

Detroit Metropolitan Wayne County

Thu 12/11

6:45 pm-9:35 pm

1 stop3h 50m

Des Moines

Sat 12/13

5:25 am-7:50 pm

2 stops13h 25m

$366

DetroitDes Moines

DTW - DSM

DTWDSM

Detroit Metropolitan Wayne County

Fri 12/5

5:57 pm-11:35 pm

1 stop6h 38m

Des Moines

Mon 12/8

5:40 am-8:00 pm

1 stop13h 20m

$377

DetroitDes Moines

DTW - DSM

DTWDSM

Detroit Metropolitan Wayne County

Tue 12/2

9:40 am-11:44 pm

1 stop15h 04m

Des Moines

Mon 12/8

5:40 am-8:00 pm

1 stop13h 20m

$379

DetroitDes Moines

DTW - DSM

DTWDSM

Detroit Metropolitan Wayne County

Thu 12/11

7:47 pm-8:46 pm

Nonstop1h 59m

Des Moines

Sat 12/13

6:17 am-9:09 am

Nonstop1h 52m

$399

DetroitDes Moines

DTW - DSM

DTWDSM

Detroit Metropolitan Wayne County

Thu 12/11

7:47 pm-8:46 pm

Nonstop1h 59m

Des Moines

Sat 12/13

3:30 pm-10:36 pm

1 stop6h 06m

$409

DetroitDes Moines

DTW - DSM

DTWDSM

Detroit Metropolitan Wayne County

Fri 12/19

5:49 am-10:50 am

1 stop6h 01m

Des Moines

Thu 12/25

11:15 am-10:30 pm

1 stop10h 15m

$442

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Des Moines from

How to get the cheapest flight ticket from Detroit Metropolitan Wayne County Airport to Des Moines

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Des Moines?

If you’re not able to fly to Des Moines in July, then June is your next best option. Flight prices from Detroit Metropolitan Wayne County Airport to Des Moines during June average around $379.

What is the cheapest day to depart on your flight to Des Moines?

The cheapest day to depart from Detroit Metropolitan Wayne County Airport to Des Moines is on a Wednesday. Travelers who choose to depart for Des Moines on a Wednesday will often find tickets for as low as $409. Flights from Detroit Metropolitan Wayne County Airport to Des Moines on a Tuesday will generally be more expensive and average around $557. Keep in mind that these prices on both days could fluctuate depending on the season and the demand.

What is the cheapest time of day to depart on your flight to Des Moines?

According to our data, the cheapest time of day to fly to Des Moines is in the evening. momondo users have found flights departing from Detroit Metropolitan Wayne County Airport to Des Moines in the evening for as low as $409. Keep in mind that these prices may fluctuate based on what airline you choose and the time of year you plan to travel. Try not to purchase tickets in the afternoon because they tend to be around $557. Of course, these prices can vary depending on the time of year and what airport you fly to.

What is the cheapest Detroit Metropolitan Wayne County to Des Moines flight route?

Fly from Detroit Metropolitan Wayne County to Des Moines for the best Detroit Metropolitan Wayne County - Des Moines flight prices

What cabin class options are available on Detroit Metropolitan Wayne County to Des Moines flights?

There are 3 cabin classes available to choose from on Detroit Metropolitan Wayne County to Des Moines flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Detroit Metropolitan Wayne County Airport to Des Moines flights?

No. A direct flight is the cheapest option for a flight between Detroit Metropolitan Wayne County Airport to Des Moines.

How have Detroit Metropolitan Wayne County Airport to Des Moines flight prices changed over time?

When to book flights from Detroit Metropolitan Wayne County Airport to Des Moines

Are you open to changing your travel dates? Check out the ideal times to fly from Detroit Metropolitan Wayne County Airport to Des Moines according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Detroit Metropolitan Wayne County Airport to Des Moines (DTW to DSM) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Detroit Metropolitan Wayne County Airport to Des Moines

Best Price Found

$498

Fastest flight time

1h 58m

Direct flights

Mon, Tue, Wed, Thu, Fri and Sat

Airports in Des Moines

1 airport
The best flight deal from Detroit Metropolitan Wayne County Airport to Des Moines found on momondo in the last 72 hours is $498
The fastest flight from Detroit Metropolitan Wayne County Airport to Des Moines takes 1h 58m
Direct flights go from Detroit Metropolitan Wayne County Airport to Des Moines on Monday, Tuesday, Wednesday, Thursday, Friday and Saturday. The only airline offering direct flights is Delta.
There is 1 airport near Des Moines: Des Moines (DSM)
Search flight deals

  • How far is Detroit Metropolitan Wayne County to Des Moines by plane?

    A flight from Detroit Metropolitan Wayne County to Des Moines will travel around 529.6 mi. Typically, this will take 1h 59m by plane in normal conditions.

  • When did momondo last update prices for flights from Detroit Metropolitan Wayne County Airport to Des Moines Airport?

    Prices for flights from Detroit Metropolitan Wayne County Airport to Des Moines Airport are updated daily.

  • How many operators does momondo search for flights from Detroit Metropolitan Wayne County Airport to Des Moines Airport?

  • How old do you have to be to fly from Detroit Metropolitan Wayne County Airport to Des Moines Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Detroit Metropolitan Wayne County Airport to Des Moines Airport.

  • What documentation or ID do you need to fly to Des Moines Airport?

    The travel and health documents required for your trip to Des Moines Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Des Moines Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular plane model from Detroit Metropolitan Wayne County Airport to Des Moines?

  • What is the most popular airline from Detroit Metropolitan Wayne County Airport to Des Moines?

Best airlines flying from Detroit Metropolitan Wayne County Airport to Des Moines

Compare and see reviews for airlines that fly from Detroit Metropolitan Wayne County Airport to Des Moines with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $314Free CancellationRating
7.9
8,003 reviews
Search Delta flights

  • Delta Flights From Detroit Metropolitan Wayne County Airport to Des Moines

    Delta is one of the most popular airlines flying from Detroit Metropolitan Wayne County Airport to Des Moines, operating 16 flights/week on average for this route. A good Delta flight deal for Detroit Metropolitan Wayne County Airport to Des Moines starts from $314 round-trip, up to an average price of $435. Our users have rated Delta at 7.9/10.

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
West Des Moines
Ames
Ankeny
Altoona
Urbandale
Clive
Newton
Pella
Johnston
Osceola
Boone
Norwalk
Grinnell
Oskaloosa
Carlisle

Why use momondo?

Why should I use momondo to find a flight deal from Detroit to Des Moines?

It is quick and easy to find Detroit to Des Moines flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Des Moines that suits you.

Can I find flights from Detroit to Des Moines with flexible booking policies on momondo?

All flight searches from Detroit to Des Moines on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Detroit to Des Moines?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Des Moines from Detroit.

I’m not ready to book a flight from Detroit to Des Moines right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Detroit to Des Moines flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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