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Cheap flights from Des Moines to Rome from $395

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Des Moines to Rome departing on 10/15. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Des Moines to Rome

Cheap round-trip flights

Enter your travel dates to find the best prices.
Scandinavian Airlines Logo
2:34 pm - 6:35 pm
DSM
-
FCO
21h 01m
2 stops
Scandinavian Airlines Logo
11:55 am - 10:37 pm
FCO
-
DSM
41h 42m
2 stops
$780Scandinavian Airlines
Mon, Aug 24 - Thu, Sep 3
United Airlines Logo
6:00 am - 8:15 am
DSM
-
FCO
19h 15m
2 stops
United Airlines Logo
11:30 am - 2:16 pm
FCO
-
DSM
33h 46m
2 stops
$804United Airlines
Tue, Aug 11 - Thu, Aug 20
United Airlines Logo
6:15 am - 7:55 am
DSM
-
FCO
19h 40m
2 stops
United Airlines Logo
11:15 am - 2:11 pm
FCO
-
DSM
33h 56m
2 stops
$805United Airlines
Tue, Oct 27 - Tue, Nov 10
Air Canada Logo
5:45 am - 9:15 am
DSM
-
FCO
20h 30m
2 stops
Air Canada Logo
11:30 am - 2:16 pm
FCO
-
DSM
33h 46m
2 stops
$808Air Canada
Mon, Aug 17 - Thu, Aug 27
Lufthansa Logo
11:32 am - 7:55 am
DSM
-
FCO
13h 23m
1 stop
Lufthansa Logo
9:45 am - 10:53 pm
FCO
-
DSM
20h 08m
1 stop
$812Lufthansa
Tue, Aug 11 - Thu, Aug 20
Air Canada Logo
3:20 pm - 10:20 am
DSM
-
FCO
36h 00m
2 stops
Air Canada Logo
11:30 am - 10:26 am
FCO
-
DSM
29h 56m
2 stops
$813Air Canada
Sat, Aug 15 - Thu, Aug 27
Scandinavian Airlines Logo
2:34 pm - 6:35 pm
DSM
-
FCO
21h 01m
2 stops
Scandinavian Airlines Logo
7:25 pm - 10:26 pm
FCO
-
DSM
34h 01m
2 stops
$814Scandinavian Airlines
Mon, Aug 24 - Wed, Sep 9
Lufthansa Logo
8:00 am - 7:45 am
DSM
-
FCO
17h 45m
1 stop
Lufthansa Logo
1:30 pm - 11:01 pm
FCO
-
DSM
16h 31m
2 stops
$819Lufthansa
Sun, Oct 25 - Tue, Nov 10
Multiple Airlines Logo
11:32 am - 11:45 am
DSM
-
FCO
17h 13m
3 stops
Multiple Airlines Logo
2:20 pm - 10:26 am
FCO
-
DSM
27h 06m
2 stops
$821Multiple Airlines
Tue, Aug 11 - Thu, Aug 20
United Airlines Logo
9:13 am - 12:20 pm
DSM
-
FCO
20h 07m
1 stop
United Airlines Logo
1:20 pm - 10:53 pm
FCO
-
DSM
16h 33m
2 stops
$823United Airlines
Mon, Aug 17 - Fri, Aug 28

KLM flights from Des Moines to Rome

Our best KLM deals on Des Moines to Rome flight tickets
KLM
Aug 11
DSM5:40 amDes Moines
22h 10m
1 stop
FCO10:50 amRome Fiumicino
Aug 20
FCO9:00 amRome Fiumicino
18h 58m
1 stop
DSM8:58 pmDes Moines
$824
KLM
Aug 15
DSM6:06 pmDes Moines
33h 54m
1 stop
FCO11:00 amRome Fiumicino
Aug 25
FCO6:30 amRome Fiumicino
14h 34m
2 stops
DSM2:04 pmDes Moines
$830
KLM
Aug 15
DSM4:11 pmDes Moines
35h 39m
1 stop
FCO10:50 amRome Fiumicino
Aug 25
FCO9:45 amRome Fiumicino
15h 05m
1 stop
DSM5:50 pmDes Moines
$831

United Airlines flights from Des Moines to Rome

Our best United Airlines deals on Des Moines to Rome flight tickets
United Airlines
Aug 11
DSM6:00 amDes Moines
19h 15m
2 stops
FCO8:15 amRome Fiumicino
Aug 20
FCO11:30 amRome Fiumicino
33h 46m
2 stops
DSM2:16 pmDes Moines
$804
United Airlines
Oct 27
DSM6:15 amDes Moines
19h 40m
2 stops
FCO7:55 amRome Fiumicino
Nov 10
FCO11:15 amRome Fiumicino
33h 56m
2 stops
DSM2:11 pmDes Moines
$805
United Airlines
Aug 17
DSM9:13 amDes Moines
20h 07m
1 stop
FCO12:20 pmRome Fiumicino
Aug 28
FCO1:20 pmRome Fiumicino
16h 33m
2 stops
DSM10:53 pmDes Moines
$823

momondo Fare Finder

 
Customize your flight search to find flights from Des Moines to Rome that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated May 31, 2026.
Use the filters below to find and compare flights from Des Moines to Rome that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Des MoinesRome

DSM - FCO

DSMFCO

Des Moines

Mon 8/24

2:34 pm-6:35 pm

2 stops21h 01m

Rome Fiumicino

Thu 9/3

11:55 am-10:37 pm

2 stops41h 42m

$780

Des MoinesRome

DSM - FCO

DSMFCO

Des Moines

Tue 8/11

6:00 am-8:15 am

2 stops19h 15m

Rome Fiumicino

Thu 8/20

11:30 am-2:16 pm

2 stops33h 46m

$804

Des MoinesRome

DSM - FCO

DSMFCO

Des Moines

Tue 10/27

6:15 am-7:55 am

2 stops19h 40m

Rome Fiumicino

Tue 11/10

11:15 am-2:11 pm

2 stops33h 56m

$805

Des MoinesRome

DSM - FCO

DSMFCO

Des Moines

Mon 8/17

5:45 am-9:15 am

2 stops20h 30m

Rome Fiumicino

Thu 8/27

11:30 am-2:16 pm

2 stops33h 46m

$808
Quickest round-trip

Des MoinesRome

DSM - FCO

DSMFCO

Des Moines

Tue 8/11

11:32 am-7:55 am

1 stop13h 23m

Rome Fiumicino

Thu 8/20

9:45 am-10:53 pm

1 stop20h 08m

$812

Des MoinesRome

DSM - FCO

DSMFCO

Des Moines

Sat 8/15

3:20 pm-10:20 am

2 stops36h 00m

Rome Fiumicino

Thu 8/27

11:30 am-10:26 am

2 stops29h 56m

$813

Des MoinesRome

DSM - FCO

DSMFCO

Des Moines

Mon 8/24

2:34 pm-6:35 pm

2 stops21h 01m

Rome Fiumicino

Wed 9/9

7:25 pm-10:26 pm

2 stops34h 01m

$814

Des MoinesRome

DSM - FCO

DSMFCO

Des Moines

Sun 10/25

8:00 am-7:45 am

1 stop17h 45m

Rome Fiumicino

Tue 11/10

1:30 pm-11:01 pm

2 stops16h 31m

$819

Des MoinesRome

DSM - FCO

DSMFCO

Des Moines

Tue 8/11

11:32 am-11:45 am

3 stops17h 13m

Rome Fiumicino

Thu 8/20

2:20 pm-10:26 am

2 stops27h 06m

$821

Des MoinesRome

DSM - FCO

DSMFCO

Des Moines

Mon 8/17

9:13 am-12:20 pm

1 stop20h 07m

Rome Fiumicino

Fri 8/28

1:20 pm-10:53 pm

2 stops16h 33m

$823

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Rome from

How to get the cheapest flight ticket from Des Moines to Rome

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Des Moines and Rome?

What is the cheapest month to fly to Rome?

The cheapest month to fly to Rome from Des Moines is in January. Flight prices, which tend to average around $457, are often lower during this time because this is during the off-season. If you aren’t able to travel to Rome during the month of January, then flying in February is also cheap. Prices for this month can be found on momondo for an average of $510.

Can stopping save me money on Des Moines to Rome flights?

You could potentially save up to 15% on your flight if you consider stops on a Des Moines to Rome flight.

When to book flights from Des Moines to Rome

Are you open to changing your travel dates? Check out the ideal times to fly from Des Moines to Rome according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Des Moines to Rome (DSM to ROM) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to Rome

Fastest flight time

13h 29m

Direct flights

None
The fastest flight from Des Moines to Rome takes 13h 29m
There are no direct flights from Des Moines to Rome. There are no popular flight routes from Des Moines to Rome.
Search flight deals

Frequently asked questions about flying from Des Moines to Rome

  • How far is Des Moines to Rome by plane?

    The straight-line distance from Des Moines to Rome is 5055.2 mi. In terms of flight time, this usually takes a little over 13h 29m.

  • When did momondo last update prices for flights from Des Moines Airport to Rome?

    Prices for flights from Des Moines Airport to Rome are updated daily.

  • How many operators does momondo search for flights from Des Moines Airport to Rome?

  • How old do you have to be to fly from Des Moines Airport to Rome?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Des Moines Airport to Rome.

  • What documentation or ID do you need to fly to Rome?

    The necessary travel and health documents for your Rome trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Des Moines to Rome?

Best airlines flying from Des Moines to Rome

Compare and see reviews for airlines that fly from Des Moines to Rome with momondo
Airline
Rating
Free Cancellation
Price
United AirlinesPriceFrom $491Free CancellationRating
7.4
9,768 reviews
Search United Airlines flights
DeltaPriceFrom $655Free CancellationRating
7.9
8,412 reviews
Search Delta flights

Traveling to a place near Rome?

Book flights to Rome if you plan to visit one of these locations
Fiumicino
Civitavecchia
Cassino
Gaeta
Orvieto
Montepulciano
Ponza
Ladispoli
Pienza
Chianciano Terme
Tivoli
Sperlonga
Terracina
Ciampino
Saturnia
Santa Marinella
Anzio
Orbetello
Grosseto
Ascoli Piceno

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to Rome?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Des Moines to Rome. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Des Moines to Rome with flexible booking policies on momondo?

Flights from Des Moines to Rome with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Des Moines to Rome?

momondo helps you find the best flight between Des Moines and Rome by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Des Moines to Rome right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Des Moines to Rome flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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Find better results for your trip to Italy

Fly into one of these airports located in Rome

Airports listed have a maximum distance of 14.7 mi from Rome
Rome Ciampino Airport
Rome Fiumicino Airport