Latest deals
Insights
FAQs
Reviews
Price Alerts

Cheap flights from Des Moines to Mexico from $137

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Des Moines to Mexico departing on 1/25. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

Discover deals from 900+ travel sites with momondo.

Save money when you book flights with momondo

Big names and deals

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Price Alerts

Not ready to book? to track prices.
Search flight deals

Find the cheapest flights from Des Moines to Mexico

Cheap round-trip flights

Enter your travel dates to find the best prices.
Frontier Logo
7:36 pm - 1:09 pm
DSM
-
CUN
16h 33m1 stop
Frontier Logo
8:24 am - 12:20 pm
CUN
-
DSM
27h 56m1 stop
$333Frontier
Thu, Mar 5 - Mon, Mar 9
Multiple Airlines Logo
2:58 pm - 10:00 am
DSM
-
CUN
18h 02m2 stops
Multiple Airlines Logo
1:21 pm - 10:46 pm
CUN
-
DSM
10h 25m1 stop
$359Multiple Airlines
Thu, Jan 22 - Thu, Jan 29
American Airlines Logo
4:00 pm - 2:24 pm
DSM
-
CZM
22h 24m1 stop
American Airlines Logo
3:25 pm - 11:29 pm
CZM
-
DSM
8h 04m1 stop
$381American Airlines
Thu, Jan 22 - Thu, Jan 29
American Airlines Logo
4:00 pm - 2:24 pm
DSM
-
CZM
22h 24m1 stop
American Airlines Logo
3:24 pm - 10:50 am
CZM
-
DSM
19h 26m1 stop
$386American Airlines
Sun, Jan 25 - Sun, Feb 1
Aeromexico Logo
6:54 am - 3:00 pm
DSM
-
CZM
8h 06m1 stop
Aeromexico Logo
3:05 pm - 10:29 pm
CZM
-
DSM
7h 24m1 stop
$409Aeromexico
Mon, Jan 12 - Thu, Jan 29
Delta Logo
5:35 am - 1:50 pm
DSM
-
CZM
8h 15m1 stop
Delta Logo
3:05 pm - 9:35 am
CZM
-
DSM
18h 30m2 stops
$414Delta
Tue, Jan 20 - Fri, Jan 23
Aeromexico Logo
5:35 am - 1:50 pm
DSM
-
CZM
8h 15m1 stop
Aeromexico Logo
3:05 pm - 10:29 pm
CZM
-
DSM
7h 24m1 stop
$425Aeromexico
Thu, Jan 22 - Thu, Jan 29
Delta Logo
5:35 am - 1:50 pm
DSM
-
CZM
8h 15m1 stop
Delta Logo
3:05 pm - 10:29 pm
CZM
-
DSM
7h 24m1 stop
$433Delta
Tue, Jan 20 - Sat, Jan 24
United Airlines Logo
8:10 am - 7:22 pm
DSM
-
MLM
11h 12m1 stop
United Airlines Logo
8:00 am - 10:30 pm
MLM
-
DSM
14h 30m1 stop
$539United Airlines
Mon, Jan 26 - Mon, Feb 2
United Airlines Logo
6:48 pm - 1:02 pm
DSM
-
PVR
18h 14m2 stops
United Airlines Logo
12:19 pm - 10:44 am
PVR
-
DSM
21h 25m2 stops
$551United Airlines
Sun, Jan 11 - Tue, Mar 31

American Airlines flights from Des Moines to Mexico

Our best American Airlines deals on Des Moines to Mexico flight tickets
American Airlines
Jan 22
DSM4:00 pmDes Moines
22h 24m
1 stop
CZM2:24 pmCozumel
Jan 29
CZM3:25 pmCozumel
8h 04m
1 stop
DSM11:29 pmDes Moines
$381
Find similar
American Airlines
Jan 25
DSM4:00 pmDes Moines
22h 24m
1 stop
CZM2:24 pmCozumel
Feb 1
CZM3:24 pmCozumel
19h 26m
1 stop
DSM10:50 amDes Moines
$386
Find similar
American Airlines
Jan 18
DSM4:00 pmDes Moines
22h 24m
1 stop
CZM2:24 pmCozumel
Jan 23
CZM3:24 pmCozumel
7h 59m
1 stop
DSM11:23 pmDes Moines
$417
Find similar

United Airlines flights from Des Moines to Mexico

Our best United Airlines deals on Des Moines to Mexico flight tickets
United Airlines
Jan 12
DSM3:04 pmDes Moines
22h 19m
1 stop
CZM1:23 pmCozumel
Jan 17
CZM3:21 pmCozumel
8h 23m
1 stop
DSM11:44 pmDes Moines
$442
Find similar
United Airlines
Feb 28
DSM6:49 pmDes Moines
18h 34m
2 stops
CZM1:23 pmCozumel
Mar 7
CZM4:42 pmCozumel
6h 02m
1 stop
DSM10:44 pmDes Moines
$454
Find similar
United Airlines
Feb 28
DSM3:24 pmDes Moines
21h 59m
2 stops
CZM1:23 pmCozumel
Mar 7
CZM4:42 pmCozumel
16h 48m
2 stops
DSM9:30 amDes Moines
$459
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Des Moines to Mexico that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated December 11, 2025.
Use the filters below to find and compare flights from Des Moines to Mexico that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Des MoinesCancún

DSM - CUN

DSMCUN

Des Moines

Thu 3/5

7:36 pm-1:09 pm

1 stop16h 33m

Cancun

Mon 3/9

8:24 am-12:20 pm

1 stop27h 56m

$333

Des MoinesCancún

DSM - CUN

DSMCUN

Des Moines

Thu 1/22

2:58 pm-10:00 am

2 stops18h 02m

Cancun

Thu 1/29

1:21 pm-10:46 pm

1 stop10h 25m

$359

Des MoinesCozumel

DSM - CZM

DSMCZM

Des Moines

Thu 1/22

4:00 pm-2:24 pm

1 stop22h 24m

Cozumel

Thu 1/29

3:25 pm-11:29 pm

1 stop8h 04m

$381

Des MoinesCozumel

DSM - CZM

DSMCZM

Des Moines

Sun 1/25

4:00 pm-2:24 pm

1 stop22h 24m

Cozumel

Sun 2/1

3:24 pm-10:50 am

1 stop19h 26m

$386

Des MoinesCozumel

DSM - CZM

DSMCZM

Des Moines

Mon 1/12

6:54 am-3:00 pm

1 stop8h 06m

Cozumel

Thu 1/29

3:05 pm-10:29 pm

1 stop7h 24m

$409

Des MoinesCozumel

DSM - CZM

DSMCZM

Des Moines

Tue 1/20

5:35 am-1:50 pm

1 stop8h 15m

Cozumel

Fri 1/23

3:05 pm-9:35 am

2 stops18h 30m

$414

Des MoinesCozumel

DSM - CZM

DSMCZM

Des Moines

Thu 1/22

5:35 am-1:50 pm

1 stop8h 15m

Cozumel

Thu 1/29

3:05 pm-10:29 pm

1 stop7h 24m

$425

Des MoinesCozumel

DSM - CZM

DSMCZM

Des Moines

Tue 1/20

5:35 am-1:50 pm

1 stop8h 15m

Cozumel

Sat 1/24

3:05 pm-10:29 pm

1 stop7h 24m

$433

Des MoinesMorelia

DSM - MLM

DSMMLM

Des Moines

Mon 1/26

8:10 am-7:22 pm

1 stop11h 12m

Morelia

Mon 2/2

8:00 am-10:30 pm

1 stop14h 30m

$539

Des MoinesPuerto Vallarta

DSM - PVR

DSMPVR

Des Moines

Sun 1/11

6:48 pm-1:02 pm

2 stops18h 14m

Puerto Vallarta Ordaz

Tue 3/31

12:19 pm-10:44 am

2 stops21h 25m

$551

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
1
2

See travel insights to Mexico from

How to get the cheapest flight ticket from Des Moines to Mexico

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Mexico?

If you’re not able to fly to Mexico in September, then October is your next best option. Flight prices from Des Moines to Mexico during October average around $519.

What is the cheapest day to depart on your flight to Mexico?

The cheapest day to depart on your flight to Mexico is on a Tuesday when prices can be found for as low as $514. This is often the case because there is less demand to fly during this day of the week. If your travel schedule is flexible, try to avoid departing on a Thursday because tickets tend to average around $631. These prices are subject to change though, so be sure to set up a Price Alert for flights to Mexico.

What is the cheapest time of day to depart on your flight to Mexico?

Our data shows that the cheapest Des Moines to Mexico flights are usually those with departure times in the evening. Our users have found flights to Mexico in the evening for as low as $535. If you have a flexible travel schedule, then try to avoid flying at noon when prices are $596 on average. Flights to Mexico from Des Moines at noon are generally more expensive because this time of day is more convenient for travelers’ schedules.

How far in advance should I book a flight to Mexico?

You are more likely to see cheaper flights to Mexico from Des Moines when booking weeks ahead of your departure date. In general, you can expect to find flights to Mexico for around $593 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Mexico from Des Moines for as low as $483 on momondo.

Can stopping save me money on Des Moines to Mexico flights?

You could potentially save up to 22% on your flight if you consider stops on a Des Moines to Mexico flight.

Cheap Des Moines to Mexico flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to Mexico

Fastest flight time

5h 49m

Direct flights

None
The fastest flight from Des Moines to Mexico takes 5h 49m
There are no direct flights from Des Moines to Mexico. There are no popular flight routes from Des Moines to Mexico.
Search flight deals

  • When did momondo last update prices for flights from Des Moines Airport to Mexico?

    Prices for flights from Des Moines Airport to Mexico are refreshed on a daily basis.

  • How many operators does momondo search for flights from Des Moines Airport to Mexico?

  • How old do you have to be to fly from Des Moines Airport to Mexico?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Des Moines Airport to Mexico.

  • What documentation or ID do you need to fly to Mexico?

    The travel and health documents you'll need for your trip to Mexico may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Mexico. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

Best airlines flying from Des Moines to Mexico

Compare and see reviews for airlines that fly from Des Moines to Mexico with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $250Free CancellationRating
7.9
8,005 reviews
Search Delta flights
United AirlinesPriceFrom $379Free CancellationRating
7.4
9,095 reviews
Search United Airlines flights
American AirlinesPriceFrom $389Free CancellationRating
7.2
11,050 reviews
Search American Airlines flights
AeromexicoPriceFrom $410Free CancellationRating
7.4
1,643 reviews
Search Aeromexico flights
SouthwestPriceFrom $547Free CancellationRating
7.9
4,253 reviews
Search Southwest flights

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to Mexico?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Mexico from Des Moines.

Can I find flights from Des Moines to Mexico with flexible booking policies on momondo?

momondo does allow users to show only those flights to Mexico from Des Moines which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Des Moines to Mexico?

momondo helps you find the best flight between Des Moines and Mexico by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Des Moines to Mexico right now. Can momondo alert me if prices change?

Price alerts on flights to Mexico from Des Moines are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

An easier way to manage your Mexico trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
Start using Trips
Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.
1 adult
Sat 1/10
Sat 1/17
By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to Mexico

Popular cities in Mexico

Popular flights according to clicks in the last 7 days on momondo
Flights to Cancúnfrom $196
Flights to Mexico Cityfrom $190
Flights to Guadalajarafrom $195
Flights to Puerto Vallartafrom $257
Flights to San José del Cabofrom $171
Flights to Tijuanafrom $244
Flights to León, Guanajuatofrom $195
Flights to Monterreyfrom $203
Flights to Oaxacafrom $216
Flights to Méridafrom $184
Flights to Santiago de Querétarofrom $138
Flights to Moreliafrom $168