What is the cheapest airline that flies from Des Moines to Mexico?

Frontier, Aeromexico, and Delta are the most popular carriers operating from Des Moines to Mexico

What airlines fly to Mexico?

American Airlines, United Airlines and Delta are the top three most popular airlines that fly to Mexico from Des Moines according to our data. American Airlines is the first choice among our users, with 49% of people opting to fly with this airline when traveling to Mexico. Keep in mind that there are 5 different airlines that fly to Mexico on a routine basis, so you have a few additional options to choose from.

When did momondo last update prices for flights from Des Moines Airport to Mexico?

Prices for flights from Des Moines Airport to Mexico are refreshed on a daily basis.

How many operators does momondo search for flights from Des Moines Airport to Mexico?

As of June 2026, there are 5 operators available to choose from for flights from Des Moines Airport to Mexico.

How old do you have to be to fly from Des Moines Airport to Mexico?

The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Des Moines Airport to Mexico.

What documentation or ID do you need to fly to Mexico?

The travel and health documents you'll need for your trip to Mexico may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Mexico. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

$180 Cheap Flights from Des Moines to Mexico in 2026

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Des Moines to Mexico

Round-trip

One-way

Last minute

Cheap round-trip flights

Enter your travel dates to find the best prices.

8:00 am - 6:47 pm

DSM

GDL

11h 47m

2 stops

10:37 am - 7:48 pm

GDL

DSM

8h 11m

1 stop

$436Multiple Airlines

Sun, Sep 6 - Fri, Sep 18

1:37 pm - 10:15 pm

DSM

MEX

9h 38m

1 stop

10:35 pm - 7:04 pm

MEX

DSM

19h 29m

2 stops

$441Multiple Airlines

Fri, Jul 17 - Thu, Jul 23

4:48 pm - 2:09 pm

DSM

CZM

21h 21m

1 stop

3:11 pm - 11:58 pm

CZM

DSM

8h 47m

1 stop

$492American Airlines

Tue, Jul 21 - Tue, Jul 28

6:33 am - 8:03 pm

DSM

CUN

13h 30m

1 stop

3:56 pm - 9:01 am

CUN

DSM

17h 05m

1 stop

$513American Airlines

Wed, Aug 5 - Wed, Aug 12

6:15 am - 2:42 pm

DSM

CZM

8h 27m

1 stop

3:52 pm - 10:30 pm

CZM

DSM

6h 38m

1 stop

$550United Airlines

Tue, Aug 11 - Tue, Aug 18

5:21 pm - 2:42 pm

DSM

CZM

21h 21m

2 stops

3:52 pm - 10:30 pm

CZM

DSM

6h 38m

1 stop

$554United Airlines

Tue, Aug 11 - Tue, Aug 18

2:15 pm - 8:15 am

DSM

BJX

19h 00m

2 stops

8:12 am - 10:29 pm

BJX

DSM

13h 17m

2 stops

$584Aeromexico

Tue, Oct 6 - Tue, Oct 13

2:15 pm - 9:01 am

DSM

PVR

18h 46m

2 stops

2:21 pm - 10:29 pm

PVR

DSM

8h 08m

1 stop

$593Aeromexico

Sat, Nov 7 - Wed, Nov 11

5:40 am - 11:56 pm

DSM

MID

19h 16m

2 stops

6:59 am - 10:37 pm

MID

DSM

14h 38m

2 stops

$619Delta

Tue, Aug 11 - Tue, Aug 18

4:11 pm - 9:35 am

DSM

MID

18h 24m

2 stops

5:46 am - 10:37 pm

MID

DSM

15h 51m

2 stops

$899Delta

Sat, Aug 8 - Sat, Aug 15

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American Airlines flights from Des Moines to Mexico

Our best American Airlines deals on Des Moines to Mexico flight tickets

American Airlines

Jul 21

DSM4:48 pmDes Moines

21h 21m

1 stop

CZM2:09 pmCozumel Intl

Jul 28

CZM3:11 pmCozumel Intl

8h 47m

1 stop

DSM11:58 pmDes Moines

$492

American Airlines

Aug 5

DSM6:33 amDes Moines

13h 30m

1 stop

CUN8:03 pmCancun

Aug 12

CUN3:56 pmCancun

17h 05m

1 stop

DSM9:01 amDes Moines

$513

American Airlines

Aug 8

DSM4:13 pmDes Moines

18h 54m

1 stop

CUN11:07 amCancun

Aug 15

CUN8:00 amCancun

15h 16m

1 stop

DSM11:16 pmDes Moines

$537

Aeromexico flights from Des Moines to Mexico

Our best Aeromexico deals on Des Moines to Mexico flight tickets

Aeromexico

Sep 23

DSM11:31 amDes Moines

22h 09m

2 stops

CUN9:40 amCancun

Sep 28

CUN7:38 pmCancun

22h 31m

2 stops

DSM6:09 pmDes Moines

$517

Aeromexico

Oct 6

DSM2:15 pmDes Moines

19h 00m

2 stops

BJX8:15 amLeón Del Bajio

Oct 13

BJX8:12 amLeón Del Bajio

13h 17m

2 stops

DSM10:29 pmDes Moines

$584

Aeromexico

Nov 7

DSM2:15 pmDes Moines

18h 46m

2 stops

PVR9:01 amPuerto Vallarta Ordaz

Nov 11

PVR2:21 pmPuerto Vallarta Ordaz

8h 08m

1 stop

DSM10:29 pmDes Moines

$593

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Des MoinesGuadalajara

DSM - GDL

DSMGDL

Des Moines

Sun 9/6

8:00 am-6:47 pm

2 stops11h 47m

Guadalajara Miguel Hidal

Fri 9/18

10:37 am-7:48 pm

1 stop8h 11m

$436

Des MoinesMexico City

DSM - MEX

DSMMEX

Des Moines

Fri 7/17

1:37 pm-10:15 pm

1 stop9h 38m

Mexico City Benito Juarez

Thu 7/23

10:35 pm-7:04 pm

2 stops19h 29m

$441

Des MoinesCozumel

DSM - CZM

DSMCZM

Des Moines

Tue 7/21

4:48 pm-2:09 pm

1 stop21h 21m

Cozumel Intl

Tue 7/28

3:11 pm-11:58 pm

1 stop8h 47m

$492

Des MoinesCancún

DSM - CUN

DSMCUN

Des Moines

Wed 8/5

6:33 am-8:03 pm

1 stop13h 30m

Cancun

Wed 8/12

3:56 pm-9:01 am

1 stop17h 05m

$513

Quickest round-trip

Des MoinesCozumel

DSM - CZM

DSMCZM

Des Moines

Tue 8/11

6:15 am-2:42 pm

1 stop8h 27m

Cozumel Intl

Tue 8/18

3:52 pm-10:30 pm

1 stop6h 38m

$550

Des MoinesCozumel

DSM - CZM

DSMCZM

Des Moines

Tue 8/11

5:21 pm-2:42 pm

2 stops21h 21m

Cozumel Intl

Tue 8/18

3:52 pm-10:30 pm

1 stop6h 38m

$554

Des MoinesLeón

DSM - BJX

DSMBJX

Des Moines

Tue 10/6

2:15 pm-8:15 am

2 stops19h 00m

León Del Bajio

Tue 10/13

8:12 am-10:29 pm

2 stops13h 17m

$584

Des MoinesPuerto Vallarta

DSM - PVR

DSMPVR

Des Moines

Sat 11/7

2:15 pm-9:01 am

2 stops18h 46m

Puerto Vallarta Ordaz

Wed 11/11

2:21 pm-10:29 pm

1 stop8h 08m

$593

Des MoinesMérida

DSM - MID

DSMMID

Des Moines

Tue 8/11

5:40 am-11:56 pm

2 stops19h 16m

Mérida Rejon

Tue 8/18

6:59 am-10:37 pm

2 stops14h 38m

$619

Des MoinesMérida

DSM - MID

DSMMID

Des Moines

Sat 8/8

4:11 pm-9:35 am

2 stops18h 24m

Mérida Rejon

Sat 8/15

5:46 am-10:37 pm

2 stops15h 51m

$899

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Des Moines to Mexico

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the cheapest month to fly to Mexico?

If you’re not able to fly to Mexico in June, then April is your next best option. Flight prices from Des Moines to Mexico during April average around $210.

How far in advance should I book a flight from Des Moines to Mexico?

You are more likely to see cheaper flights to Mexico from Des Moines when booking weeks ahead of your departure date. In general, you can expect to find flights to Mexico for around $643 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Mexico from Des Moines for as low as $539 on momondo.

Can stopping save me money on Des Moines to Mexico flights?

You could potentially save up to 7% on your flight if you consider stops on a Des Moines to Mexico flight.

Cheap Des Moines to Mexico flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to Mexico

Fastest flight time	5h 51m
Direct flights	None

The fastest flight from Des Moines to Mexico takes 5h 51m

There are no direct flights from Des Moines to Mexico. There are no popular flight routes from Des Moines to Mexico.

Search flight deals

Frequently asked questions about flying from Des Moines to Mexico

When did momondo last update prices for flights from Des Moines Airport to Mexico?
Prices for flights from Des Moines Airport to Mexico are refreshed on a daily basis.
How many operators does momondo search for flights from Des Moines Airport to Mexico?
As of June 2026, there are 5 operators available to choose from for flights from Des Moines Airport to Mexico.
How old do you have to be to fly from Des Moines Airport to Mexico?
The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Des Moines Airport to Mexico.
What documentation or ID do you need to fly to Mexico?
The travel and health documents you'll need for your trip to Mexico may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Mexico. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

Best airlines flying from Des Moines to Mexico

Compare and see reviews for airlines that fly from Des Moines to Mexico with momondo

Airline	Rating	Free Cancellation	Price
Aeromexico	PriceFrom $276	Free Cancellation	Rating 7.4 1,485 reviews	Search Aeromexico flights
American Airlines	PriceFrom $366	Free Cancellation	Rating 7.1 11,776 reviews	Search American Airlines flights
United Airlines	PriceFrom $379	Free Cancellation	Rating 7.4 9,899 reviews	Search United Airlines flights
Delta	PriceFrom $398	Free Cancellation	Rating 7.8 8,455 reviews	Search Delta flights
Southwest	PriceFrom $569	Free Cancellation	Rating 7.9 4,246 reviews	Search Southwest flights

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to Mexico?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Mexico from Des Moines.

Can I find flights from Des Moines to Mexico with flexible booking policies on momondo?

momondo does allow users to show only those flights to Mexico from Des Moines which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Des Moines to Mexico?

momondo helps you find the best flight between Des Moines and Mexico by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Des Moines to Mexico right now. Can momondo alert me if prices change?

Price alerts on flights to Mexico from Des Moines are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.