What airlines fly to Mexico?

American Airlines, United Airlines and Delta are the top three most popular airlines that fly to Mexico from Des Moines according to our data. American Airlines is the first choice among our users, with 46% of people opting to fly with this airline when traveling to Mexico. Keep in mind that there are 5 different airlines that fly to Mexico on a routine basis, so you have a few additional options to choose from.

What is the cheapest airline that flies from Des Moines to Mexico?

Frontier, American Airlines, and Aeromexico are the most popular carriers operating from Des Moines to Mexico

When did momondo last update prices for flights from Des Moines Airport to Mexico?

Prices for flights from Des Moines Airport to Mexico are refreshed on a daily basis.

How many operators does momondo search for flights from Des Moines Airport to Mexico?

As of August 2026, there are 5 operators available to choose from for flights from Des Moines Airport to Mexico.

How old do you have to be to fly from Des Moines Airport to Mexico?

The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Des Moines Airport to Mexico.

What documentation or ID do you need to fly to Mexico?

The travel and health documents you'll need for your trip to Mexico may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Mexico. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

$170 Cheap Flights from Des Moines to Mexico in 2026

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Des Moines to Mexico

Round-trip

One-way

Last minute

Cheap round-trip flights

Enter your travel dates to find the best prices.

2:31 pm - 4:25 pmDSM Des Moines-GDL Guadalajara Miguel Hidal

26h 54m1 stop Denver Intl

7:58 am - 1:18 pmGDL Guadalajara Miguel Hidal-DSM Des Moines

28h 20m1 stop Denver Intl

$392Frontier

Wed, Oct 14 - Tue, Oct 20

2:31 pm - 4:25 pmDSM Des Moines-GDL Guadalajara Miguel Hidal

26h 54m1 stop Denver Intl

8:46 am - 1:18 pmGDL Guadalajara Miguel Hidal-DSM Des Moines

27h 32m2 stops Las Vegas Harry Reid Intl Denver Intl

$418Frontier

Wed, Oct 14 - Tue, Oct 20

11:31 am - 7:50 pmDSM Des Moines-CUN Cancun

8h 19m1 stop Atlanta Hartsfield-Jackson

7:41 pm - 6:09 pmCUN Cancun-DSM Des Moines

22h 28m2 stops Mexico City Benito Juarez Atlanta Hartsfield-Jackson

$502Aeromexico

Mon, Sep 21 - Mon, Sep 28

11:31 am - 7:50 pmDSM Des Moines-CUN Cancun

8h 19m1 stop Atlanta Hartsfield-Jackson

7:41 pm - 6:09 pmCUN Cancun-DSM Des Moines

22h 28m2 stops Mexico City Benito Juarez Atlanta Hartsfield-Jackson

$515Aeromexico

Mon, Sep 21 - Mon, Sep 28

6:10 am - 12:10 pmDSM Des Moines-CUN Cancun

6h 00m1 stop Chicago Midway

3:20 pm - 9:55 pmCUN Cancun-DSM Des Moines

6h 35m1 stop Chicago Midway

$540Southwest

Tue, Sep 29 - Wed, Oct 7

6:45 am - 3:00 pmDSM Des Moines-CUN Cancun

8h 15m1 stop Denver Intl

11:00 am - 9:55 pmCUN Cancun-DSM Des Moines

10h 55m2 stops Houston Hobby Denver Intl

$540Southwest

Sun, Oct 25 - Fri, Oct 30

7:42 pm - 9:57 amDSM Des Moines-CUN Cancun

14h 15m1 stop Dallas/Fort Worth

7:20 am - 11:07 pmCUN Cancun-DSM Des Moines

15h 47m1 stop Dallas/Fort Worth

$560American Airlines

Sat, Oct 24 - Fri, Oct 30

6:00 am - 9:17 pmDSM Des Moines-CUN Cancun

14h 17m1 stop Dallas/Fort Worth

3:25 pm - 11:57 pmCUN Cancun-DSM Des Moines

9h 32m1 stop Charlotte Douglas

$560American Airlines

Sun, Nov 8 - Fri, Nov 13

5:45 am - 7:50 pmDSM Des Moines-CUN Cancun

14h 05m1 stop Atlanta Hartsfield-Jackson

2:08 pm - 9:02 pmCUN Cancun-DSM Des Moines

6h 54m1 stop Minneapolis St Paul

$564Delta

Tue, Sep 29 - Wed, Oct 7

6:00 am - 2:00 pmDSM Des Moines-CUN Cancun

7h 00m1 stop Detroit Metropolitan Wayne County

8:00 am - 6:05 pmCUN Cancun-DSM Des Moines

11h 05m1 stop Atlanta Hartsfield-Jackson

$564Delta

Sun, Nov 15 - Wed, Nov 25

Cheap last minute flights

Enter your travel dates to find the best prices.

4:11 pm - 8:36 amDSM Des Moines-GDL Guadalajara Miguel Hidal

17h 25m2 stops Atlanta Hartsfield-Jackson Mexico City Benito Juarez

12:50 pm - 10:37 pmGDL Guadalajara Miguel Hidal-DSM Des Moines

8h 47m1 stop Atlanta Hartsfield-Jackson

$643Multiple Airlines

Sat, Aug 15 - Sat, Aug 29

4:11 pm - 8:36 amDSM Des Moines-GDL Guadalajara Miguel Hidal

17h 25m2 stops Atlanta Hartsfield-Jackson Mexico City Benito Juarez

8:37 am - 10:37 pmGDL Guadalajara Miguel Hidal-DSM Des Moines

13h 00m2 stops Mexico City Benito Juarez Atlanta Hartsfield-Jackson

$643Multiple Airlines

Sat, Aug 15 - Sat, Aug 29

3:20 pm - 2:42 pmDSM Des Moines-CZM Cozumel Intl

23h 22m2 stops Chicago O'Hare Intl Houston George Bush Intcntl

3:52 pm - 12:20 pmCZM Cozumel Intl-DSM Des Moines

20h 28m2 stops Houston George Bush Intcntl Chicago O'Hare Intl

$811United Airlines

Sat, Aug 15 - Fri, Aug 21

9:32 am - 10:49 amDSM Des Moines-GDL Guadalajara Miguel Hidal

26h 17m1 stop Dallas/Fort Worth

3:54 pm - 11:16 pmGDL Guadalajara Miguel Hidal-DSM Des Moines

6h 22m1 stop Dallas/Fort Worth

$835American Airlines

Sat, Aug 15 - Sat, Aug 29

6:15 am - 2:37 pmDSM Des Moines-CUN Cancun

8h 22m1 stop Houston George Bush Intcntl

3:43 pm - 11:44 pmCUN Cancun-DSM Des Moines

8h 01m1 stop Denver Intl

$848United Airlines

Sat, Aug 15 - Sat, Aug 22

5:40 am - 10:34 pmDSM Des Moines-CUN Cancun

16h 54m2 stops Atlanta Hartsfield-Jackson Mexico City Benito Juarez

8:05 am - 10:37 pmCUN Cancun-DSM Des Moines

14h 32m1 stop Atlanta Hartsfield-Jackson

$848Aeromexico

Sat, Aug 15 - Sat, Aug 22

9:32 am - 10:49 amDSM Des Moines-GDL Guadalajara Miguel Hidal

26h 17m1 stop Dallas/Fort Worth

3:54 pm - 11:16 pmGDL Guadalajara Miguel Hidal-DSM Des Moines

6h 22m1 stop Dallas/Fort Worth

$849American Airlines

Sat, Aug 15 - Sat, Aug 29

5:40 am - 2:22 pmDSM Des Moines-CUN Cancun

8h 42m1 stop Atlanta Hartsfield-Jackson

8:05 am - 10:37 pmCUN Cancun-DSM Des Moines

14h 32m1 stop Atlanta Hartsfield-Jackson

$873Delta

Sat, Aug 15 - Fri, Aug 21

5:40 am - 12:28 pmDSM Des Moines-PVR Puerto Vallarta Ordaz

7h 48m1 stop Atlanta Hartsfield-Jackson

1:39 pm - 10:37 pmPVR Puerto Vallarta Ordaz-DSM Des Moines

7h 58m1 stop Atlanta Hartsfield-Jackson

$898Delta

Fri, Aug 14 - Fri, Aug 21

7:20 am - 2:40 pmDSM Des Moines-CUN Cancun

7h 20m1 stop Denver Intl

11:35 am - 10:10 pmCUN Cancun-DSM Des Moines

10h 35m2 stops Houston Hobby Chicago Midway

$955Southwest

Sat, Aug 15 - Fri, Aug 21

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American Airlines flights from Des Moines to Mexico

Our best American Airlines deals on Des Moines to Mexico flight tickets

American Airlines

Nov 8

DSM6:00 amDes Moines

14h 17m

1 stop

CUN9:17 pmCancun

Nov 13

CUN3:25 pmCancun

9h 32m

1 stop

DSM11:57 pmDes Moines

$560

American Airlines

Nov 8

DSM7:37 pmDes Moines

13h 59m

2 stops

CUN10:36 amCancun

Nov 13

CUN7:00 amCancun

8h 39m

1 stop

DSM2:39 pmDes Moines

$565

American Airlines

Sep 23

DSM4:14 pmDes Moines

5h 26m

1 stop

MTY8:40 pmMonterrey Gen Mariano Escobedo

Sep 30

MTY4:42 pmMonterrey Gen Mariano Escobedo

5h 30m

1 stop

DSM11:12 pmDes Moines

$567

United Airlines flights from Des Moines to Mexico

Our best United Airlines deals on Des Moines to Mexico flight tickets

United Airlines

Sep 16

DSM5:21 pmDes Moines

21h 21m

2 stops

CZM2:42 pmCozumel Intl

Sep 23

CZM3:52 pmCozumel Intl

6h 38m

1 stop

DSM10:30 pmDes Moines

$573

United Airlines

Jan 20

DSM8:00 amDes Moines

6h 42m

1 stop

CZM3:42 pmCozumel Intl

Jan 25

CZM4:50 pmCozumel Intl

6h 40m

1 stop

DSM10:30 pmDes Moines

$600

United Airlines

Dec 2

DSM8:00 amDes Moines

13h 07m

3 stops

BJX9:07 pmLeón Del Bajio

Dec 14

BJX3:50 pmLeón Del Bajio

6h 40m

1 stop

DSM10:30 pmDes Moines

$608

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Des MoinesGuadalajara

DSM Des Moines - GDL Guadalajara Miguel Hidal

DSMGDL

Des Moines

Wed 10/14

2:31 pm-4:25 pm

1 stop26h 54m

Guadalajara Miguel Hidal

Tue 10/20

7:58 am-1:18 pm

1 stop28h 20m

$392

Des MoinesGuadalajara

DSM Des Moines - GDL Guadalajara Miguel Hidal

DSMGDL

Des Moines

Wed 10/14

2:31 pm-4:25 pm

1 stop26h 54m

Guadalajara Miguel Hidal

Tue 10/20

8:46 am-1:18 pm

2 stops27h 32m

$418

Des MoinesCancún

DSM Des Moines - CUN Cancun

DSMCUN

Des Moines

Mon 9/21

11:31 am-7:50 pm

1 stop8h 19m

Cancun

Mon 9/28

7:41 pm-6:09 pm

2 stops22h 28m

$502

Des MoinesCancún

DSM Des Moines - CUN Cancun

DSMCUN

Des Moines

Mon 9/21

11:31 am-7:50 pm

1 stop8h 19m

Cancun

Mon 9/28

7:41 pm-6:09 pm

2 stops22h 28m

$515

Quickest round-trip

Des MoinesCancún

DSM Des Moines - CUN Cancun

DSMCUN

Des Moines

Tue 9/29

6:10 am-12:10 pm

1 stop6h 00m

Cancun

Wed 10/7

3:20 pm-9:55 pm

1 stop6h 35m

$540

Des MoinesCancún

DSM Des Moines - CUN Cancun

DSMCUN

Des Moines

Sun 10/25

6:45 am-3:00 pm

1 stop8h 15m

Cancun

Fri 10/30

11:00 am-9:55 pm

2 stops10h 55m

$540

Des MoinesCancún

DSM Des Moines - CUN Cancun

DSMCUN

Des Moines

Sat 10/24

7:42 pm-9:57 am

1 stop14h 15m

Cancun

Fri 10/30

7:20 am-11:07 pm

1 stop15h 47m

$560

Des MoinesCancún

DSM Des Moines - CUN Cancun

DSMCUN

Des Moines

Sun 11/8

6:00 am-9:17 pm

1 stop14h 17m

Cancun

Fri 11/13

3:25 pm-11:57 pm

1 stop9h 32m

$560

Des MoinesCancún

DSM Des Moines - CUN Cancun

DSMCUN

Des Moines

Tue 9/29

5:45 am-7:50 pm

1 stop14h 05m

Cancun

Wed 10/7

2:08 pm-9:02 pm

1 stop6h 54m

$564

Des MoinesCancún

DSM Des Moines - CUN Cancun

DSMCUN

Des Moines

Sun 11/15

6:00 am-2:00 pm

1 stop7h 00m

Cancun

Wed 11/25

8:00 am-6:05 pm

1 stop11h 05m

$564

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Des Moines to Mexico

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the cheapest month to fly to Mexico?

If you’re not able to fly to Mexico in September, then January is your next best option. Flight prices from Des Moines to Mexico during January average around $587.

Can stopping save me money on Des Moines to Mexico flights?

You could potentially save up to 7% on your flight if you consider stops on a Des Moines to Mexico flight.

Cheap Des Moines to Mexico flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to Mexico

Fastest flight time	5h 33m
Direct flights	None

The fastest flight from Des Moines to Mexico takes 5h 33m

There are no direct flights from Des Moines to Mexico. There are no popular flight routes from Des Moines to Mexico.

Search flight deals

Frequently asked questions about flying from Des Moines to Mexico

When did momondo last update prices for flights from Des Moines Airport to Mexico?
Prices for flights from Des Moines Airport to Mexico are refreshed on a daily basis.
How many operators does momondo search for flights from Des Moines Airport to Mexico?
As of August 2026, there are 5 operators available to choose from for flights from Des Moines Airport to Mexico.
How old do you have to be to fly from Des Moines Airport to Mexico?
The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Des Moines Airport to Mexico.
What documentation or ID do you need to fly to Mexico?
The travel and health documents you'll need for your trip to Mexico may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Mexico. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

Best airlines flying from Des Moines to Mexico

Compare and see reviews for airlines that fly from Des Moines to Mexico with momondo

Airline	Rating	Free Cancellation	Price
Aeromexico	PriceFrom $276	Free Cancellation	Rating 7.4 1,472 reviews	Search Aeromexico flights
United Airlines	PriceFrom $423	Free Cancellation	Rating 7.4 10,111 reviews	Search United Airlines flights
American Airlines	PriceFrom $441	Free Cancellation	Rating 7.1 11,910 reviews	Search American Airlines flights
Delta	PriceFrom $465	Free Cancellation	Rating 7.8 8,505 reviews	Search Delta flights
Southwest	PriceFrom $569	Free Cancellation	Rating 8.0 4,220 reviews	Search Southwest flights

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to Mexico?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Mexico from Des Moines.

Can I find flights from Des Moines to Mexico with flexible booking policies on momondo?

momondo does allow users to show only those flights to Mexico from Des Moines which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Des Moines to Mexico?

momondo helps you find the best flight between Des Moines and Mexico by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Des Moines to Mexico right now. Can momondo alert me if prices change?

Price alerts on flights to Mexico from Des Moines are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.