What airlines fly to Mexico?

American Airlines, United Airlines and Delta are the top three most popular airlines that fly to Mexico from Des Moines according to our data. American Airlines is the first choice among our users, with 51% of people opting to fly with this airline when traveling to Mexico. Keep in mind that there are 5 different airlines that fly to Mexico on a routine basis, so you have a few additional options to choose from.

What is the cheapest airline that flies from Des Moines to Mexico?

American Airlines, Delta, and Aeromexico are the most popular carriers operating from Des Moines to Mexico

When did momondo last update prices for flights from Des Moines Airport to Mexico?

Prices for flights from Des Moines Airport to Mexico are refreshed on a daily basis.

How many operators does momondo search for flights from Des Moines Airport to Mexico?

As of March 2026, there are 5 operators available to choose from for flights from Des Moines Airport to Mexico.

How old do you have to be to fly from Des Moines Airport to Mexico?

The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Des Moines Airport to Mexico.

What documentation or ID do you need to fly to Mexico?

The travel and health documents you'll need for your trip to Mexico may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Mexico. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

$208 Cheap Flights from Des Moines to Mexico in 2026

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Find the cheapest flights from Des Moines to Mexico

Round-trip

One-way

Last minute

Cheap round-trip flights

Enter your travel dates to find the best prices.

8:23 pm - 12:04 pm

DSM

CUN

15h 41m

1 stop

3:39 pm - 1:31 pm

CUN

DSM

21h 52m

1 stop

$261Frontier

Mon, May 4 - Tue, May 12

8:23 pm - 12:04 pm

DSM

CUN

15h 41m

1 stop

11:05 am - 1:31 pm

CUN

DSM

50h 26m

2 stops

$353Frontier

Mon, May 4 - Mon, May 11

2:44 pm - 8:15 pm

DSM

CUN

5h 31m

1 stop

3:02 pm - 10:32 pm

CUN

DSM

7h 30m

1 stop

$382Aeromexico

Tue, May 5 - Tue, May 12

5:44 am - 12:08 pm

DSM

CUN

6h 24m

1 stop

12:05 pm - 11:59 pm

CUN

DSM

11h 54m

1 stop

$395American Airlines

Wed, Apr 15 - Wed, Apr 22

2:44 pm - 8:15 pm

DSM

CUN

5h 31m

1 stop

6:58 am - 10:32 pm

CUN

DSM

15h 34m

2 stops

$401Aeromexico

Tue, May 5 - Tue, May 12

7:16 pm - 10:30 am

DSM

SJD

17h 14m

2 stops

1:44 pm - 10:43 pm

SJD

DSM

6h 59m

1 stop

$492United Airlines

Mon, Apr 13 - Thu, Apr 16

5:45 am - 11:31 am

DSM

SJD

7h 46m

1 stop

2:19 pm - 9:54 am

SJD

DSM

17h 35m

2 stops

$497Delta

Mon, Apr 27 - Tue, May 5

5:30 am - 1:43 pm

DSM

SJD

10h 13m

1 stop

11:52 am - 11:17 pm

SJD

DSM

9h 25m

1 stop

$502United Airlines

Wed, Apr 15 - Wed, Apr 22

7:05 pm - 10:22 am

DSM

PVR

16h 17m

1 stop

12:38 pm - 11:49 pm

PVR

DSM

10h 11m

1 stop

$512American Airlines

Sat, May 2 - Wed, May 6

7:00 am - 5:49 pm

DSM

SJD

12h 49m

2 stops

6:01 am - 10:34 pm

SJD

DSM

14h 33m

2 stops

$512Delta

Tue, Apr 14 - Fri, Apr 17

Aeromexico flights from Des Moines to Mexico

Our best Aeromexico deals on Des Moines to Mexico flight tickets

Aeromexico

May 5

DSM2:44 pmDes Moines

5h 31m

1 stop

CUN8:15 pmCancun

May 12

CUN3:02 pmCancun

7h 30m

1 stop

DSM10:32 pmDes Moines

$382

Aeromexico

May 5

DSM2:44 pmDes Moines

5h 31m

1 stop

CUN8:15 pmCancun

May 12

CUN6:58 amCancun

15h 34m

2 stops

DSM10:32 pmDes Moines

$401

Aeromexico

May 5

DSM2:44 pmDes Moines

19h 01m

2 stops

CUN9:45 amCancun

May 12

CUN8:08 amCancun

14h 24m

2 stops

DSM10:32 pmDes Moines

$417

American Airlines flights from Des Moines to Mexico

Our best American Airlines deals on Des Moines to Mexico flight tickets

American Airlines

Apr 15

DSM5:44 amDes Moines

6h 24m

1 stop

CUN12:08 pmCancun

Apr 22

CUN12:05 pmCancun

11h 54m

1 stop

DSM11:59 pmDes Moines

$395

American Airlines

May 16

DSM7:05 pmDes Moines

14h 55m

1 stop

CUN10:00 amCancun

May 20

CUN1:08 pmCancun

10h 41m

1 stop

DSM11:49 pmDes Moines

$423

American Airlines

May 16

DSM7:05 pmDes Moines

16h 52m

1 stop

CUN11:57 amCancun

May 20

CUN2:35 pmCancun

7h 43m

1 stop

DSM10:18 pmDes Moines

$443

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Des MoinesCancún

DSM - CUN

DSMCUN

Des Moines

Mon 5/4

8:23 pm-12:04 pm

1 stop15h 41m

Cancun

Tue 5/12

3:39 pm-1:31 pm

1 stop21h 52m

$261

Des MoinesCancún

DSM - CUN

DSMCUN

Des Moines

Mon 5/4

8:23 pm-12:04 pm

1 stop15h 41m

Cancun

Mon 5/11

11:05 am-1:31 pm

2 stops50h 26m

$353

Quickest round-trip

Des MoinesCancún

DSM - CUN

DSMCUN

Des Moines

Tue 5/5

2:44 pm-8:15 pm

1 stop5h 31m

Cancun

Tue 5/12

3:02 pm-10:32 pm

1 stop7h 30m

$382

Des MoinesCancún

DSM - CUN

DSMCUN

Des Moines

Wed 4/15

5:44 am-12:08 pm

1 stop6h 24m

Cancun

Wed 4/22

12:05 pm-11:59 pm

1 stop11h 54m

$395

Des MoinesCancún

DSM - CUN

DSMCUN

Des Moines

Tue 5/5

2:44 pm-8:15 pm

1 stop5h 31m

Cancun

Tue 5/12

6:58 am-10:32 pm

2 stops15h 34m

$401

Des MoinesSan José del Cabo

DSM - SJD

DSMSJD

Des Moines

Mon 4/13

7:16 pm-10:30 am

2 stops17h 14m

San José del Cabo Los Cabos

Thu 4/16

1:44 pm-10:43 pm

1 stop6h 59m

$492

Des MoinesSan José del Cabo

DSM - SJD

DSMSJD

Des Moines

Mon 4/27

5:45 am-11:31 am

1 stop7h 46m

San José del Cabo Los Cabos

Tue 5/5

2:19 pm-9:54 am

2 stops17h 35m

$497

Des MoinesSan José del Cabo

DSM - SJD

DSMSJD

Des Moines

Wed 4/15

5:30 am-1:43 pm

1 stop10h 13m

San José del Cabo Los Cabos

Wed 4/22

11:52 am-11:17 pm

1 stop9h 25m

$502

Des MoinesPuerto Vallarta

DSM - PVR

DSMPVR

Des Moines

Sat 5/2

7:05 pm-10:22 am

1 stop16h 17m

Puerto Vallarta Ordaz

Wed 5/6

12:38 pm-11:49 pm

1 stop10h 11m

$512

Des MoinesSan José del Cabo

DSM - SJD

DSMSJD

Des Moines

Tue 4/14

7:00 am-5:49 pm

2 stops12h 49m

San José del Cabo Los Cabos

Fri 4/17

6:01 am-10:34 pm

2 stops14h 33m

$512

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Des Moines to Mexico

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the cheapest month to fly to Mexico?

If you’re not able to fly to Mexico in September, then October is your next best option. Flight prices from Des Moines to Mexico during October average around $519.

How far in advance should I book a flight to Mexico?

You are more likely to see cheaper flights to Mexico from Des Moines when booking weeks ahead of your departure date. In general, you can expect to find flights to Mexico for around $597 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Mexico from Des Moines for as low as $494 on momondo.

Can stopping save me money on Des Moines to Mexico flights?

You could potentially save up to 26% on your flight if you consider stops on a Des Moines to Mexico flight.

Cheap Des Moines to Mexico flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to Mexico

Fastest flight time	5h 33m
Direct flights	None

The fastest flight from Des Moines to Mexico takes 5h 33m

There are no direct flights from Des Moines to Mexico. There are no popular flight routes from Des Moines to Mexico.

Search flight deals

When did momondo last update prices for flights from Des Moines Airport to Mexico?
Prices for flights from Des Moines Airport to Mexico are refreshed on a daily basis.
How many operators does momondo search for flights from Des Moines Airport to Mexico?
As of March 2026, there are 5 operators available to choose from for flights from Des Moines Airport to Mexico.
How old do you have to be to fly from Des Moines Airport to Mexico?
The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Des Moines Airport to Mexico.
What documentation or ID do you need to fly to Mexico?
The travel and health documents you'll need for your trip to Mexico may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Mexico. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

Best airlines flying from Des Moines to Mexico

Compare and see reviews for airlines that fly from Des Moines to Mexico with momondo

Airline	Rating	Free Cancellation	Price
Aeromexico	PriceFrom $233	Free Cancellation	Rating 7.4 1,563 reviews	Search Aeromexico flights
American Airlines	PriceFrom $366	Free Cancellation	Rating 7.1 11,488 reviews	Search American Airlines flights
United Airlines	PriceFrom $379	Free Cancellation	Rating 7.4 9,452 reviews	Search United Airlines flights
Delta	PriceFrom $397	Free Cancellation	Rating 7.9 8,313 reviews	Search Delta flights
Southwest	PriceFrom $569	Free Cancellation	Rating 8.0 4,325 reviews	Search Southwest flights

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to Mexico?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Mexico from Des Moines.

Can I find flights from Des Moines to Mexico with flexible booking policies on momondo?

momondo does allow users to show only those flights to Mexico from Des Moines which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Des Moines to Mexico?

momondo helps you find the best flight between Des Moines and Mexico by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Des Moines to Mexico right now. Can momondo alert me if prices change?

Price alerts on flights to Mexico from Des Moines are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.