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Cheap flights from Des Moines to Mexico from $155

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Des Moines to Mexico departing on 2/26. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Des Moines to Mexico

Cheap round-trip flights

Enter your travel dates to find the best prices.
Frontier Logo
7:27 pm - 5:17 pm
DSM
-
CUN
20h 50m
1 stop
Frontier Logo
12:24 pm - 6:19 pm
CUN
-
DSM
30h 55m
1 stop
$367Frontier
Sun, Feb 15 - Thu, Feb 19
Delta Logo
12:04 pm - 9:11 pm
DSM
-
CUN
8h 07m
1 stop
Delta Logo
3:00 pm - 9:20 pm
CUN
-
DSM
7h 20m
1 stop
$412Delta
Wed, Feb 18 - Wed, Feb 25
Multiple Airlines Logo
7:27 pm - 5:17 pm
DSM
-
CUN
20h 50m
1 stop
Multiple Airlines Logo
10:13 am - 11:12 pm
CUN
-
DSM
13h 59m
2 stops
$419Multiple Airlines
Sun, Feb 15 - Thu, Feb 19
Multiple Airlines Logo
7:17 pm - 11:23 pm
DSM
-
CUN
27h 06m
2 stops
Multiple Airlines Logo
11:08 am - 7:16 pm
CUN
-
DSM
9h 08m
1 stop
$422Multiple Airlines
Mon, Mar 2 - Sat, Mar 7
United Airlines Logo
5:30 am - 5:50 pm
DSM
-
CUN
11h 20m
2 stops
United Airlines Logo
3:18 pm - 9:41 pm
CUN
-
DSM
7h 23m
1 stop
$438United Airlines
Wed, Feb 25 - Wed, Mar 4
American Airlines Logo
6:08 pm - 12:11 pm
DSM
-
CUN
17h 03m
1 stop
American Airlines Logo
6:59 pm - 10:34 am
CUN
-
DSM
16h 35m
1 stop
$449American Airlines
Sat, Feb 21 - Thu, Feb 26
Aeromexico Logo
6:50 am - 4:25 pm
DSM
-
CUN
8h 35m
1 stop
Aeromexico Logo
12:25 pm - 8:49 pm
CUN
-
DSM
9h 24m
1 stop
$464Aeromexico
Mon, Mar 2 - Wed, Mar 4
Aeromexico Logo
5:24 am - 2:09 pm
DSM
-
SJD
9h 45m
1 stop
Aeromexico Logo
1:45 pm - 10:28 pm
SJD
-
DSM
7h 43m
1 stop
$473Aeromexico
Tue, Feb 17 - Wed, Feb 18
United Airlines Logo
5:30 am - 2:42 pm
DSM
-
CZM
10h 12m
2 stops
United Airlines Logo
3:52 pm - 10:43 pm
CZM
-
DSM
5h 51m
1 stop
$503United Airlines
Tue, Mar 31 - Tue, Apr 7
American Airlines Logo
5:05 am - 3:28 pm
DSM
-
SJD
11h 23m
2 stops
American Airlines Logo
9:50 am - 11:59 pm
SJD
-
DSM
13h 09m
1 stop
$507American Airlines
Tue, Mar 3 - Fri, Mar 6

United Airlines flights from Des Moines to Mexico

Our best United Airlines deals on Des Moines to Mexico flight tickets
United Airlines
Feb 25
DSM7:52 amDes Moines
7h 07m
1 stop
CUN3:59 pmCancun
Mar 4
CUN1:37 pmCancun
7h 35m
1 stop
DSM8:12 pmDes Moines
$438
United Airlines
Mar 4
DSM5:30 amDes Moines
11h 20m
2 stops
CUN5:50 pmCancun
Mar 10
CUN3:51 pmCancun
6h 53m
1 stop
DSM10:44 pmDes Moines
$475
United Airlines
Feb 17
DSM7:52 amDes Moines
8h 58m
1 stop
CUN5:50 pmCancun
Feb 23
CUN3:18 pmCancun
7h 23m
1 stop
DSM9:41 pmDes Moines
$478

Aeromexico flights from Des Moines to Mexico

Our best Aeromexico deals on Des Moines to Mexico flight tickets
Aeromexico
Mar 2
DSM6:50 amDes Moines
8h 35m
1 stop
CUN4:25 pmCancun
Mar 4
CUN12:25 pmCancun
9h 24m
1 stop
DSM8:49 pmDes Moines
$464
Aeromexico
Feb 17
DSM5:24 amDes Moines
18h 03m
2 stops
SJD10:27 pmSan José del Cabo Los Cabos
Feb 18
SJD1:45 pmSan José del Cabo Los Cabos
7h 43m
1 stop
DSM10:28 pmDes Moines
$473
Aeromexico
Feb 7
DSM6:54 amDes Moines
17h 34m
2 stops
CUN1:28 amCancun
Feb 11
CUN6:01 amCancun
11h 27m
2 stops
DSM4:28 pmDes Moines
$497

momondo Fare Finder

 
Customize your flight search to find flights from Des Moines to Mexico that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated January 29, 2026.
Use the filters below to find and compare flights from Des Moines to Mexico that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Des MoinesCancún

DSM - CUN

DSMCUN

Des Moines

Sun 2/15

7:27 pm-5:17 pm

1 stop20h 50m

Cancun

Thu 2/19

12:24 pm-6:19 pm

1 stop30h 55m

$367

Des MoinesCancún

DSM - CUN

DSMCUN

Des Moines

Wed 2/18

12:04 pm-9:11 pm

1 stop8h 07m

Cancun

Wed 2/25

3:00 pm-9:20 pm

1 stop7h 20m

$412

Des MoinesCancún

DSM - CUN

DSMCUN

Des Moines

Sun 2/15

7:27 pm-5:17 pm

1 stop20h 50m

Cancun

Thu 2/19

10:13 am-11:12 pm

2 stops13h 59m

$419

Des MoinesCancún

DSM - CUN

DSMCUN

Des Moines

Mon 3/2

7:17 pm-11:23 pm

2 stops27h 06m

Cancun

Sat 3/7

11:08 am-7:16 pm

1 stop9h 08m

$422

Des MoinesCancún

DSM - CUN

DSMCUN

Des Moines

Wed 2/25

5:30 am-5:50 pm

2 stops11h 20m

Cancun

Wed 3/4

3:18 pm-9:41 pm

1 stop7h 23m

$438

Des MoinesCancún

DSM - CUN

DSMCUN

Des Moines

Sat 2/21

6:08 pm-12:11 pm

1 stop17h 03m

Cancun

Thu 2/26

6:59 pm-10:34 am

1 stop16h 35m

$449

Des MoinesCancún

DSM - CUN

DSMCUN

Des Moines

Mon 3/2

6:50 am-4:25 pm

1 stop8h 35m

Cancun

Wed 3/4

12:25 pm-8:49 pm

1 stop9h 24m

$464

Des MoinesSan José del Cabo

DSM - SJD

DSMSJD

Des Moines

Tue 2/17

5:24 am-2:09 pm

1 stop9h 45m

San José del Cabo Los Cabos

Wed 2/18

1:45 pm-10:28 pm

1 stop7h 43m

$473

Des MoinesCozumel

DSM - CZM

DSMCZM

Des Moines

Tue 3/31

5:30 am-2:42 pm

2 stops10h 12m

Cozumel

Tue 4/7

3:52 pm-10:43 pm

1 stop5h 51m

$503

Des MoinesSan José del Cabo

DSM - SJD

DSMSJD

Des Moines

Tue 3/3

5:05 am-3:28 pm

2 stops11h 23m

San José del Cabo Los Cabos

Fri 3/6

9:50 am-11:59 pm

1 stop13h 09m

$507

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Mexico from

How to get the cheapest flight ticket from Des Moines to Mexico

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Mexico?

If you’re not able to fly to Mexico in September, then October is your next best option. Flight prices from Des Moines to Mexico during October average around $519.

How far in advance should I book a flight to Mexico?

You are more likely to see cheaper flights to Mexico from Des Moines when booking weeks ahead of your departure date. In general, you can expect to find flights to Mexico for around $594 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Mexico from Des Moines for as low as $480 on momondo.

Can stopping save me money on Des Moines to Mexico flights?

You could potentially save up to 26% on your flight if you consider stops on a Des Moines to Mexico flight.

Cheap Des Moines to Mexico flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to Mexico

Fastest flight time

5h 48m

Direct flights

None
The fastest flight from Des Moines to Mexico takes 5h 48m
There are no direct flights from Des Moines to Mexico. There are no popular flight routes from Des Moines to Mexico.
Search flight deals

  • When did momondo last update prices for flights from Des Moines Airport to Mexico?

    Prices for flights from Des Moines Airport to Mexico are refreshed on a daily basis.

  • How many operators does momondo search for flights from Des Moines Airport to Mexico?

  • How old do you have to be to fly from Des Moines Airport to Mexico?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Des Moines Airport to Mexico.

  • What documentation or ID do you need to fly to Mexico?

    The travel and health documents you'll need for your trip to Mexico may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Mexico. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

Best airlines flying from Des Moines to Mexico

Compare and see reviews for airlines that fly from Des Moines to Mexico with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $220Free CancellationRating
7.9
8,127 reviews
Search Delta flights
AeromexicoPriceFrom $249Free CancellationRating
7.4
1,586 reviews
Search Aeromexico flights
United AirlinesPriceFrom $379Free CancellationRating
7.4
9,215 reviews
Search United Airlines flights
American AirlinesPriceFrom $382Free CancellationRating
7.2
11,206 reviews
Search American Airlines flights
SouthwestPriceFrom $547Free CancellationRating
8.0
4,267 reviews
Search Southwest flights

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to Mexico?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Mexico from Des Moines.

Can I find flights from Des Moines to Mexico with flexible booking policies on momondo?

momondo does allow users to show only those flights to Mexico from Des Moines which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Des Moines to Mexico?

momondo helps you find the best flight between Des Moines and Mexico by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Des Moines to Mexico right now. Can momondo alert me if prices change?

Price alerts on flights to Mexico from Des Moines are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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Find better results for your trip to Mexico

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Popular flights according to clicks in the last 7 days on momondo
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