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Cheap flights from Des Moines to Mexico from $191

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Des Moines to Mexico departing on 11/14. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Des Moines to Mexico

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
2:56 pm - 1:13 pmDSM-CUN
21h 17m1 stop
Multiple Airlines Logo
6:02 pm - 7:03 pmCUN-DSM
26h 01m2 stops
$355Multiple Airlines
Find Deal
Sun, Dec 7 - Thu, Dec 11
Multiple Airlines Logo
2:56 pm - 1:13 pmDSM-CUN
21h 17m1 stop
Multiple Airlines Logo
2:36 pm - 10:21 pmCUN-DSM
8h 45m1 stop
$367Multiple Airlines
Find Deal
Sun, Dec 7 - Thu, Dec 11
United Airlines Logo
6:48 pm - 1:23 pmDSM-CZM
18h 35m2 stops
United Airlines Logo
2:25 pm - 10:30 pmCZM-DSM
8h 05m1 stop
$441United Airlines
Find Deal
Wed, Jan 7 - Wed, Jan 14
United Airlines Logo
6:48 pm - 1:23 pmDSM-CZM
18h 35m2 stops
United Airlines Logo
2:25 pm - 12:52 pmCZM-DSM
22h 27m2 stops
$445United Airlines
Find Deal
Wed, Jan 7 - Wed, Jan 14
American Airlines Logo
5:51 pm - 2:24 pmDSM-CZM
20h 33m1 stop
American Airlines Logo
3:24 pm - 11:23 pmCZM-DSM
7h 59m1 stop
$449American Airlines
Find Deal
Tue, Jan 6 - Tue, Jan 13
Delta Logo
5:45 am - 2:00 pmDSM-CZM
8h 15m1 stop
Delta Logo
3:15 pm - 10:28 pmCZM-DSM
7h 13m1 stop
$451Delta
Find Deal
Fri, Jan 9 - Wed, Jan 14
Delta Logo
5:45 am - 2:00 pmDSM-CZM
8h 15m1 stop
Delta Logo
3:15 pm - 10:22 amCZM-DSM
19h 07m2 stops
$455Delta
Find Deal
Fri, Jan 9 - Fri, Jan 16
American Airlines Logo
5:51 pm - 2:24 pmDSM-CZM
20h 33m1 stop
American Airlines Logo
5:30 pm - 10:50 amCZM-DSM
17h 20m1 stop
$457American Airlines
Find Deal
Sat, Jan 31 - Sat, Feb 7
Aeromexico Logo
11:04 am - 9:10 pmDSM-CUN
9h 06m1 stop
Aeromexico Logo
8:00 am - 4:30 pmCUN-DSM
9h 30m1 stop
$481Aeromexico
Find Deal
Wed, Jan 7 - Tue, Jan 13
Aeromexico Logo
7:00 am - 3:13 pmDSM-CZM
8h 13m1 stop
Aeromexico Logo
3:15 pm - 10:28 pmCZM-DSM
7h 13m1 stop
$515Aeromexico
Find Deal
Mon, Jan 12 - Thu, Jan 29

American Airlines flights from Des Moines to Mexico

Our best American Airlines deals on Des Moines to Mexico flight tickets
American Airlines
Jan 6
DSM5:51 pmDes Moines
20h 33m
1 stop
CZM2:24 pmCozumel
Jan 13
CZM3:24 pmCozumel
7h 59m
1 stop
DSM11:23 pmDes Moines
$449
Find similar
American Airlines
Jan 31
DSM5:51 pmDes Moines
20h 33m
1 stop
CZM2:24 pmCozumel
Feb 7
CZM5:30 pmCozumel
17h 20m
1 stop
DSM10:50 amDes Moines
$457
Find similar
American Airlines
Dec 6
DSM4:05 pmDes Moines
17h 27m
1 stop
CUN10:32 amCancun
Dec 13
CUN8:45 amCancun
7h 06m
1 stop
DSM2:51 pmDes Moines
$465
Find similar

Aeromexico flights from Des Moines to Mexico

Our best Aeromexico deals on Des Moines to Mexico flight tickets
Aeromexico
Jan 7
DSM11:04 amDes Moines
9h 06m
1 stop
CUN9:10 pmCancun
Jan 13
CUN8:00 amCancun
9h 30m
1 stop
DSM4:30 pmDes Moines
$481
Find similar
Aeromexico
Jan 12
DSM7:00 amDes Moines
8h 13m
1 stop
CZM3:13 pmCozumel
Jan 29
CZM3:15 pmCozumel
7h 13m
1 stop
DSM10:28 pmDes Moines
$515
Find similar
Aeromexico
Jan 13
DSM5:45 amDes Moines
10h 47m
1 stop
BJX4:32 pmLeón Del Bajio
Feb 3
BJX7:44 amLeón Del Bajio
14h 44m
2 stops
DSM10:28 pmDes Moines
$529
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Des Moines to Mexico that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated October 23, 2025.
Use the filters below to find and compare flights from Des Moines to Mexico that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Des MoinesCancún

DSM - CUN

DSMCUN

Des Moines

Sun 12/7

2:56 pm-1:13 pm

1 stop21h 17m

Cancun

Thu 12/11

6:02 pm-7:03 pm

2 stops26h 01m

$355

Des MoinesCancún

DSM - CUN

DSMCUN

Des Moines

Sun 12/7

2:56 pm-1:13 pm

1 stop21h 17m

Cancun

Thu 12/11

2:36 pm-10:21 pm

1 stop8h 45m

$367

Des MoinesCozumel

DSM - CZM

DSMCZM

Des Moines

Wed 1/7

6:48 pm-1:23 pm

2 stops18h 35m

Cozumel

Wed 1/14

2:25 pm-10:30 pm

1 stop8h 05m

$441

Des MoinesCozumel

DSM - CZM

DSMCZM

Des Moines

Wed 1/7

6:48 pm-1:23 pm

2 stops18h 35m

Cozumel

Wed 1/14

2:25 pm-12:52 pm

2 stops22h 27m

$445

Des MoinesCozumel

DSM - CZM

DSMCZM

Des Moines

Tue 1/6

5:51 pm-2:24 pm

1 stop20h 33m

Cozumel

Tue 1/13

3:24 pm-11:23 pm

1 stop7h 59m

$449

Des MoinesCozumel

DSM - CZM

DSMCZM

Des Moines

Fri 1/9

5:45 am-2:00 pm

1 stop8h 15m

Cozumel

Wed 1/14

3:15 pm-10:28 pm

1 stop7h 13m

$451

Des MoinesCozumel

DSM - CZM

DSMCZM

Des Moines

Fri 1/9

5:45 am-2:00 pm

1 stop8h 15m

Cozumel

Fri 1/16

3:15 pm-10:22 am

2 stops19h 07m

$455

Des MoinesCozumel

DSM - CZM

DSMCZM

Des Moines

Sat 1/31

5:51 pm-2:24 pm

1 stop20h 33m

Cozumel

Sat 2/7

5:30 pm-10:50 am

1 stop17h 20m

$457

Des MoinesCancún

DSM - CUN

DSMCUN

Des Moines

Wed 1/7

11:04 am-9:10 pm

1 stop9h 06m

Cancun

Tue 1/13

8:00 am-4:30 pm

1 stop9h 30m

$481

Des MoinesCozumel

DSM - CZM

DSMCZM

Des Moines

Mon 1/12

7:00 am-3:13 pm

1 stop8h 13m

Cozumel

Thu 1/29

3:15 pm-10:28 pm

1 stop7h 13m

$515

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Mexico from

How to get the cheapest flight ticket from Des Moines to Mexico

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Mexico?

If you’re not able to fly to Mexico in September, then October is your next best option. Flight prices from Des Moines to Mexico during October average around $519.

What is the cheapest day to depart on your flight to Mexico?

The cheapest day to depart on your flight to Mexico is on a Tuesday when prices can be found for as low as $514. This is often the case because there is less demand to fly during this day of the week. If your travel schedule is flexible, try to avoid departing on a Thursday because tickets tend to average around $631. These prices are subject to change though, so be sure to set up a Price Alert for flights to Mexico.

What is the cheapest time of day to depart on your flight to Mexico?

Our data shows that the cheapest Des Moines to Mexico flights are usually those with departure times in the evening. Our users have found flights to Mexico in the evening for as low as $535. If you have a flexible travel schedule, then try to avoid flying at noon when prices are $596 on average. Flights to Mexico from Des Moines at noon are generally more expensive because this time of day is more convenient for travelers’ schedules.

How far in advance should I book a flight to Mexico?

You are more likely to see cheaper flights to Mexico from Des Moines when booking weeks ahead of your departure date. In general, you can expect to find flights to Mexico for around $583 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Mexico from Des Moines for as low as $495 on momondo.

Can stopping save me money on Des Moines to Mexico flights?

You could potentially save up to 29% on your flight if you consider stops on a Des Moines to Mexico flight.

Cheap Des Moines to Mexico flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to Mexico

Direct flights

None
There are no direct flights from Des Moines to Mexico. There are no popular flight routes from Des Moines to Mexico.
Search flight deals

  • When did momondo last update prices for flights from Des Moines Airport to Mexico?

    Prices for flights from Des Moines Airport to Mexico are refreshed on a daily basis.

  • How many operators does momondo search for flights from Des Moines Airport to Mexico?

  • How old do you have to be to fly from Des Moines Airport to Mexico?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Des Moines Airport to Mexico.

  • What documentation or ID do you need to fly to Mexico?

    The travel and health documents you'll need for your trip to Mexico may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Mexico. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

Best airlines flying from Des Moines to Mexico

Compare and see reviews for airlines that fly from Des Moines to Mexico with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $250Free CancellationRating
7.9
7,981 reviews
Search Delta flights
AeromexicoPriceFrom $410Free CancellationRating
7.4
1,681 reviews
Search Aeromexico flights
American AirlinesPriceFrom $420Free CancellationRating
7.2
11,028 reviews
Search American Airlines flights
United AirlinesPriceFrom $423Free CancellationRating
7.4
8,991 reviews
Search United Airlines flights
SouthwestPriceFrom $547Free CancellationRating
8.0
4,237 reviews
Search Southwest flights

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to Mexico?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Mexico from Des Moines.

Can I find flights from Des Moines to Mexico with flexible booking policies on momondo?

momondo does allow users to show only those flights to Mexico from Des Moines which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Des Moines to Mexico?

momondo helps you find the best flight between Des Moines and Mexico by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Des Moines to Mexico right now. Can momondo alert me if prices change?

Price alerts on flights to Mexico from Des Moines are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

An easier way to manage your Mexico trip

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Sat 11/22
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Find better results for your trip to Mexico

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