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Cheap flights from Des Moines to Central America from $145

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Des Moines to Central America departing on 9/15. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Des Moines to Central America

Cheap round-trip flights

Logo
6:15 am - 4:00 pmDSM-SAL
10h 45m1 stop
Logo
8:00 am - 10:28 pmSAL-DSM
13h 28m1 stop
$337
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Wed, Sep 17 - Wed, Sep 24
Logo
6:15 am - 4:00 pmDSM-SAL
10h 45m1 stop
Logo
8:00 am - 10:28 pmSAL-DSM
13h 28m1 stop
$344
Find Deal
Wed, Aug 27 - Tue, Sep 9
United Airlines Logo
6:15 am - 8:17 pmDSM-SAL
15h 02m1 stop
United Airlines Logo
1:25 pm - 10:22 pmSAL-DSM
7h 57m1 stop
$425United Airlines
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Thu, Sep 18 - Thu, Sep 25
United Airlines Logo
6:15 am - 12:06 pmDSM-SAL
6h 51m1 stop
United Airlines Logo
1:25 pm - 10:22 pmSAL-DSM
7h 57m1 stop
$435United Airlines
Find Deal
Thu, Sep 18 - Thu, Sep 25
American Airlines Logo
6:11 pm - 11:35 amDSM-SAL
18h 24m2 stops
American Airlines Logo
12:35 pm - 9:04 amSAL-DSM
19h 29m2 stops
$438American Airlines
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Thu, Sep 18 - Thu, Sep 25
American Airlines Logo
6:11 pm - 11:35 amDSM-SAL
18h 24m2 stops
American Airlines Logo
12:35 pm - 11:28 pmSAL-DSM
9h 53m2 stops
$448American Airlines
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Thu, Sep 18 - Thu, Sep 25
Delta Logo
5:40 am - 12:56 pmDSM-PTY
7h 16m1 stop
Delta Logo
2:21 pm - 10:43 pmPTY-DSM
8h 22m1 stop
$461Delta
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Sun, Oct 12 - Tue, Oct 21
Delta Logo
5:44 am - 11:30 amDSM-GUA
6h 46m1 stop
Delta Logo
12:56 pm - 10:43 pmGUA-DSM
8h 47m1 stop
$466Delta
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Thu, Oct 2 - Mon, Oct 6
Southwest Logo
8:25 am - 6:55 pmDSM-SJO
11h 30m2 stops
Southwest Logo
8:50 am - 9:25 pmSJO-DSM
11h 35m2 stops
$497Southwest
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Wed, Sep 10 - Tue, Sep 16
Southwest Logo
7:00 am - 6:55 pmDSM-SJO
12h 55m2 stops
Southwest Logo
8:50 am - 10:50 pmSJO-DSM
13h 00m2 stops
$512Southwest
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Thu, Sep 4 - Thu, Sep 11

American Airlines flights from Des Moines to Central America

Our best American Airlines deals on Des Moines to Central America flight tickets
American Airlines
Sep 18
DSM6:11 pmDes Moines
18h 24m
2 stops
SAL11:35 amSan Salvador El Salvador Intl
Sep 25
SAL12:35 pmSan Salvador El Salvador Intl
19h 29m
2 stops
DSM9:04 amDes Moines
$438
Find similar
American Airlines
Sep 18
DSM6:11 pmDes Moines
18h 24m
2 stops
SAL11:35 amSan Salvador El Salvador Intl
Sep 25
SAL12:35 pmSan Salvador El Salvador Intl
9h 53m
2 stops
DSM11:28 pmDes Moines
$448
Find similar
American Airlines
Nov 5
DSM5:04 pmDes Moines
21h 18m
2 stops
SAL2:22 pmSan Salvador El Salvador Intl
Nov 11
SAL3:22 pmSan Salvador El Salvador Intl
19h 22m
2 stops
DSM10:44 amDes Moines
$449
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Southwest flights from Des Moines to Central America

Our best Southwest deals on Des Moines to Central America flight tickets
Southwest
Sep 10
DSM8:25 amDes Moines
11h 30m
2 stops
SJO6:55 pmSan José Juan Santamaria Intl
Sep 16
SJO8:50 amSan José Juan Santamaria Intl
11h 35m
2 stops
DSM9:25 pmDes Moines
$497
Find similar
Southwest
Sep 4
DSM7:00 amDes Moines
12h 55m
2 stops
SJO6:55 pmSan José Juan Santamaria Intl
Sep 11
SJO8:50 amSan José Juan Santamaria Intl
13h 00m
2 stops
DSM10:50 pmDes Moines
$512
Find similar
Southwest
Aug 7
DSM7:00 amDes Moines
12h 55m
2 stops
SJO6:55 pmSan José Juan Santamaria Intl
Aug 15
SJO8:50 amSan José Juan Santamaria Intl
13h 00m
2 stops
DSM10:50 pmDes Moines
$808
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momondo Fare Finder

 
Customize your flight search to find flights from Des Moines to Central America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 5, 2025.
Use the filters below to find and compare flights from Des Moines to Central America that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Des MoinesSan Salvador

DSM - SAL

DSMSAL

Des Moines

Wed 9/17

6:15 am-4:00 pm

1 stop10h 45m

San Salvador El Salvador Intl

Wed 9/24

8:00 am-10:28 pm

1 stop13h 28m

$337

Des MoinesSan Salvador

DSM - SAL

DSMSAL

Des Moines

Wed 8/27

6:15 am-4:00 pm

1 stop10h 45m

San Salvador El Salvador Intl

Tue 9/9

8:00 am-10:28 pm

1 stop13h 28m

$344

Des MoinesSan Salvador

DSM - SAL

DSMSAL

Des Moines

Thu 9/18

6:15 am-8:17 pm

1 stop15h 02m

San Salvador El Salvador Intl

Thu 9/25

1:25 pm-10:22 pm

1 stop7h 57m

$425

Des MoinesSan Salvador

DSM - SAL

DSMSAL

Des Moines

Thu 9/18

6:15 am-12:06 pm

1 stop6h 51m

San Salvador El Salvador Intl

Thu 9/25

1:25 pm-10:22 pm

1 stop7h 57m

$435

Des MoinesSan Salvador

DSM - SAL

DSMSAL

Des Moines

Thu 9/18

6:11 pm-11:35 am

2 stops18h 24m

San Salvador El Salvador Intl

Thu 9/25

12:35 pm-9:04 am

2 stops19h 29m

$438

Des MoinesSan Salvador

DSM - SAL

DSMSAL

Des Moines

Thu 9/18

6:11 pm-11:35 am

2 stops18h 24m

San Salvador El Salvador Intl

Thu 9/25

12:35 pm-11:28 pm

2 stops9h 53m

$448

Des MoinesPanama City

DSM - PTY

DSMPTY

Des Moines

Sun 10/12

5:40 am-12:56 pm

1 stop7h 16m

Panama City Tocumen Intl

Tue 10/21

2:21 pm-10:43 pm

1 stop8h 22m

$461

Des MoinesGuatemala City

DSM - GUA

DSMGUA

Des Moines

Thu 10/2

5:44 am-11:30 am

1 stop6h 46m

Guatemala City La Aurora

Mon 10/6

12:56 pm-10:43 pm

1 stop8h 47m

$466

Des MoinesSan José

DSM - SJO

DSMSJO

Des Moines

Wed 9/10

8:25 am-6:55 pm

2 stops11h 30m

San José Juan Santamaria Intl

Tue 9/16

8:50 am-9:25 pm

2 stops11h 35m

$497

Des MoinesSan José

DSM - SJO

DSMSJO

Des Moines

Thu 9/4

7:00 am-6:55 pm

2 stops12h 55m

San José Juan Santamaria Intl

Thu 9/11

8:50 am-10:50 pm

2 stops13h 00m

$512

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Des Moines to Central America

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Central America?

In general, November is the cheapest month to fly from Des Moines to Central America. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $581. If you don’t want to visit Central America in November, then you should wait until August to fly from Des Moines, when ticket prices are also cheap, with an average price of $587.

What is the cheapest day to depart on your flight to Central America?

The cheapest day to depart from Des Moines to Central America is on a Tuesday. Travelers who choose to depart for Central America on a Tuesday will often find tickets for as low as $517. On the other hand, Saturday is the most expensive day to depart from Des Moines because it is more convenient for both business and leisure travelers. As a result, prices tend to be around $762.

What is the cheapest time of day to depart on your flight to Central America?

Our data shows that the cheapest Des Moines to Central America flights are usually those with departure times in the afternoon. Our users have found flights to Central America in the afternoon for as low as $589. Try not to purchase tickets at noon because they tend to be around $736. Of course, these prices can vary depending on the time of year and what airport you fly to.

How far in advance should I book a flight to Central America?

You are more likely to see cheaper flights to Central America from Des Moines when booking weeks ahead of your departure date. In general, you can expect to find flights to Central America for around $692 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Central America from Des Moines for as low as $498 on momondo.

Can stopping save me money on Des Moines to Central America flights?

You could potentially save up to 13% on your flight if you consider stops on a Des Moines to Central America flight.

Cheap Des Moines to Central America flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to Central America

Best Price Found

$145

Fastest flight time

6h 09m

Direct flights

None

Airports in Central America

7 airports
The best one-way flight to Central America from Des Moines in the past 72 hours is $145. The best round-trip flight deal from Des Moines to Central America found on momondo in the last 72 hours is $337.
The fastest flight from Des Moines to Central America takes 6h 09m
There are no direct flights from Des Moines to Central America. Popular non-direct routes for this connection are Des Moines Airport - San Salvador El Salvador Intl Airport, Des Moines Airport - Panama City Tocumen Intl Airport and Des Moines Airport - Guatemala City La Aurora Airport.
There are 7 airports near Central America: Guatemala City La Aurora (GUA), Panama City Tocumen Intl (PTY), Liberia (LIR), Managua Augusto C Sandino (MGA), San José Juan Santamaria Intl (SJO), Belize City Philip S.W.Goldson (BZE), San Salvador El Salvador Intl (SAL)
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  • When did momondo last update prices for flights from Des Moines Airport to Central America?

    Prices for flights from Des Moines Airport to Central America are updated daily.

  • How many operators does momondo search for flights from Des Moines Airport to Central America?

  • How old do you have to be to fly from Des Moines Airport to Central America?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Des Moines Airport to Central America.

  • What documentation or ID do you need to fly to Central America?

    The travel and health documents you'll need for your trip to Central America may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Central America. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

Best airlines flying from Des Moines to Central America

Compare and see reviews for airlines that fly from Des Moines to Central America with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $289Free CancellationRating
8.0
7,985 reviews
Search Delta flights
United AirlinesPriceFrom $369Free CancellationRating
7.4
8,916 reviews
Search United Airlines flights
American AirlinesPriceFrom $445Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to Central America?

Finding the right flight to Central America from Des Moines is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Central America quick and easy, saving you time and money.

Can I find flights from Des Moines to Central America with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Central America from Des Moines with this policy.

How can momondo help me find flights from Des Moines to Central America?

momondo provides multiple filters to help you find the best flight to Central America from Des Moines. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Des Moines to Central America right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Des Moines to Central America flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

An easier way to manage your Central America trip

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Find better results for your trip to Central America

Popular cities in Central America

Popular flights according to clicks in the last 7 days on momondo
Flights to San José, San José Provincefrom $119
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Flights to Panama Cityfrom $274
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Flights to Belize Cityfrom $274
Flights to Coxen Holefrom $330
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Flights to Davidfrom $359