What is the cheapest airline that flies from Des Moines to Central America?

United Airlines, American Airlines, and Southwest are the most popular carriers operating from Des Moines to Central America

What airlines fly to Central America?

United Airlines, American Airlines and Delta are the top three most popular airlines that fly to Central America from Des Moines according to our data. United Airlines is the first choice among our users, with 54% of people opting to fly with this airline when traveling to Central America. Keep in mind that there are 3 different airlines that fly to Central America on a routine basis, so you have a few additional options to choose from.

When did momondo last update prices for flights from Des Moines Airport to Central America?

Prices for flights from Des Moines Airport to Central America are updated daily.

How many operators does momondo search for flights from Des Moines Airport to Central America?

As of October 2026, there are 3 operators available to choose from for flights from Des Moines Airport to Central America.

How old do you have to be to fly from Des Moines Airport to Central America?

Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Des Moines Airport to Central America.

What documentation or ID do you need to fly to Central America?

The travel and health documents you'll need for your trip to Central America may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Central America. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

$287 Cheap Flights from Des Moines to Central America in 2026/27

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Des Moines to Central America

Round-trip

One-way

Last minute

Cheap round-trip flights

Enter your travel dates to find the best prices.

8:00 am - 6:50 pmDSM Des Moines-GUA Guatemala City La Aurora

10h 50m1 stop Chicago O'Hare Intl

8:05 am - 11:14 pmGUA Guatemala City La Aurora-DSM Des Moines

15h 09m1 stop Chicago O'Hare Intl

$583Multiple Airlines

Fri, Jan 22 - Fri, Jan 29

8:00 am - 6:50 pmDSM Des Moines-GUA Guatemala City La Aurora

10h 50m1 stop Chicago O'Hare Intl

8:05 am - 9:23 pmGUA Guatemala City La Aurora-DSM Des Moines

13h 18m1 stop Chicago O'Hare Intl

$583Multiple Airlines

Fri, Jan 22 - Sun, Jan 31

6:15 am - 9:35 pmDSM Des Moines-SAL San Salvador El Salvador Intl

16h 20m2 stops Chicago O'Hare Intl Newark

1:50 pm - 10:30 pmSAL San Salvador El Salvador Intl-DSM Des Moines

7h 40m1 stop Houston George Bush Intcntl

$629United Airlines

Tue, Mar 30 - Thu, Apr 1

8:00 am - 2:30 pmDSM Des Moines-SAL San Salvador El Salvador Intl

7h 30m1 stop Houston George Bush Intcntl

1:50 pm - 10:30 pmSAL San Salvador El Salvador Intl-DSM Des Moines

7h 40m1 stop Houston George Bush Intcntl

$629United Airlines

Tue, Mar 30 - Thu, Apr 1

8:00 am - 3:24 pmDSM Des Moines-SAL San Salvador El Salvador Intl

7h 24m1 stop Houston George Bush Intcntl

1:50 pm - 10:33 pmSAL San Salvador El Salvador Intl-DSM Des Moines

7h 43m1 stop Houston George Bush Intcntl

$629United Airlines

Tue, Mar 9 - Tue, Mar 23

11:27 am - 6:50 pmDSM Des Moines-GUA Guatemala City La Aurora

7h 23m1 stop Chicago O'Hare Intl

8:05 am - 11:15 pmGUA Guatemala City La Aurora-DSM Des Moines

15h 10m1 stop Chicago O'Hare Intl

$632Multiple Airlines

Thu, Dec 3 - Thu, Dec 10

3:55 pm - 12:21 pmDSM Des Moines-SAL San Salvador El Salvador Intl

20h 26m2 stops Charlotte Douglas Miami

3:13 pm - 3:41 pmSAL San Salvador El Salvador Intl-DSM Des Moines

23h 28m2 stops Miami Charlotte Douglas

$634American Airlines

Tue, Mar 9 - Tue, Mar 23

7:31 pm - 2:54 pmDSM Des Moines-BZE Belize City Philip S.W.Goldson

19h 23m2 stops Chicago O'Hare Intl Dallas/Fort Worth

2:39 pm - 11:30 pmBZE Belize City Philip S.W.Goldson-DSM Des Moines

8h 51m1 stop Dallas/Fort Worth

$638American Airlines

Sat, Dec 12 - Wed, Dec 16

6:20 am - 1:55 pmDSM Des Moines-PTY Panama City Tocumen Intl

30h 35m2 stops Detroit Metropolitan Wayne County Atlanta Hartsfield-Jackson

3:20 pm - 10:29 pmPTY Panama City Tocumen Intl-DSM Des Moines

8h 09m1 stop Atlanta Hartsfield-Jackson

$652Delta

Sun, Jan 31 - Mon, Feb 8

6:20 am - 1:55 pmDSM Des Moines-PTY Panama City Tocumen Intl

30h 35m2 stops Detroit Metropolitan Wayne County Atlanta Hartsfield-Jackson

3:20 pm - 8:52 pmPTY Panama City Tocumen Intl-DSM Des Moines

30h 32m2 stops Atlanta Hartsfield-Jackson Detroit Metropolitan Wayne County

$652Delta

Mon, Feb 1 - Wed, Feb 10

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Avianca flights from Des Moines to Central America

Our best Avianca deals on Des Moines to Central America flight tickets

Avianca

Dec 6

DSM3:20 pmDes Moines

27h 30m

1 stop

GUA6:50 pmGuatemala City La Aurora

Dec 21

GUA8:05 amGuatemala City La Aurora

23h 50m

1 stop

DSM7:55 amDes Moines

$646

Avianca

Dec 6

DSM3:20 pmDes Moines

31h 55m

2 stops

SJO11:15 pmSan José Juan Santamaria Intl

Dec 13

SJO5:35 amSan José Juan Santamaria Intl

13h 44m

2 stops

DSM7:19 pmDes Moines

$704

Avianca

Dec 4

DSM3:20 pmDes Moines

27h 30m

1 stop

GUA6:50 pmGuatemala City La Aurora

Dec 11

GUA8:00 pmGuatemala City La Aurora

47h 19m

2 stops

DSM7:19 pmDes Moines

$738

Delta flights from Des Moines to Central America

Our best Delta deals on Des Moines to Central America flight tickets

Delta

Jan 30

DSM10:55 amDes Moines

50h 00m

2 stops

PTY1:55 pmPanama City Tocumen Intl

Feb 11

PTY3:20 pmPanama City Tocumen Intl

26h 30m

2 stops

DSM4:50 pmDes Moines

$670

Delta

Jan 30

DSM4:00 pmDes Moines

44h 55m

2 stops

PTY1:55 pmPanama City Tocumen Intl

Feb 9

PTY3:20 pmPanama City Tocumen Intl

26h 30m

2 stops

DSM4:50 pmDes Moines

$688

Delta

Jan 30

DSM10:55 amDes Moines

50h 00m

2 stops

PTY1:55 pmPanama City Tocumen Intl

Feb 6

PTY3:20 pmPanama City Tocumen Intl

26h 30m

2 stops

DSM4:50 pmDes Moines

$704

momondo Fare Finder

Use the filters below to find and compare flights from Des Moines to Central America that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Des MoinesGuatemala City

DSM Des Moines - GUA Guatemala City La Aurora

DSMGUA

Des Moines

Fri 1/22

8:00 am-6:50 pm

1 stop10h 50m

Guatemala City La Aurora

Fri 1/29

8:05 am-11:14 pm

1 stop15h 09m

$583

Des MoinesGuatemala City

DSM Des Moines - GUA Guatemala City La Aurora

DSMGUA

Des Moines

Fri 1/22

8:00 am-6:50 pm

1 stop10h 50m

Guatemala City La Aurora

Sun 1/31

8:05 am-9:23 pm

1 stop13h 18m

$583

Des MoinesSan Salvador

DSM Des Moines - SAL San Salvador El Salvador Intl

DSMSAL

Des Moines

Tue 3/30

6:15 am-9:35 pm

2 stops16h 20m

San Salvador El Salvador Intl

Thu 4/1

1:50 pm-10:30 pm

1 stop7h 40m

$629

Des MoinesSan Salvador

DSM Des Moines - SAL San Salvador El Salvador Intl

DSMSAL

Des Moines

Tue 3/30

8:00 am-2:30 pm

1 stop7h 30m

San Salvador El Salvador Intl

Thu 4/1

1:50 pm-10:30 pm

1 stop7h 40m

$629

Quickest round-trip

Des MoinesSan Salvador

DSM Des Moines - SAL San Salvador El Salvador Intl

DSMSAL

Des Moines

Tue 3/9

8:00 am-3:24 pm

1 stop7h 24m

San Salvador El Salvador Intl

Tue 3/23

1:50 pm-10:33 pm

1 stop7h 43m

$629

Des MoinesGuatemala City

DSM Des Moines - GUA Guatemala City La Aurora

DSMGUA

Des Moines

Thu 12/3

11:27 am-6:50 pm

1 stop7h 23m

Guatemala City La Aurora

Thu 12/10

8:05 am-11:15 pm

1 stop15h 10m

$632

Des MoinesSan Salvador

DSM Des Moines - SAL San Salvador El Salvador Intl

DSMSAL

Des Moines

Tue 3/9

3:55 pm-12:21 pm

2 stops20h 26m

San Salvador El Salvador Intl

Tue 3/23

3:13 pm-3:41 pm

2 stops23h 28m

$634

Des MoinesBelize City

DSM Des Moines - BZE Belize City Philip S.W.Goldson

DSMBZE

Des Moines

Sat 12/12

7:31 pm-2:54 pm

2 stops19h 23m

Belize City Philip S.W.Goldson

Wed 12/16

2:39 pm-11:30 pm

1 stop8h 51m

$638

Des MoinesPanama City

DSM Des Moines - PTY Panama City Tocumen Intl

DSMPTY

Des Moines

Sun 1/31

6:20 am-1:55 pm

2 stops30h 35m

Panama City Tocumen Intl

Mon 2/8

3:20 pm-10:29 pm

1 stop8h 09m

$652

Des MoinesPanama City

DSM Des Moines - PTY Panama City Tocumen Intl

DSMPTY

Des Moines

Mon 2/1

6:20 am-1:55 pm

2 stops30h 35m

Panama City Tocumen Intl

Wed 2/10

3:20 pm-8:52 pm

2 stops30h 32m

$652

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Des Moines to Central America

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the cheapest month to fly to Central America?

In general, February is the cheapest month to fly from Des Moines to Central America. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $549. If you don’t want to visit Central America in February, then you should wait until April to fly from Des Moines, when ticket prices are also cheap, with an average price of $690.

How far in advance should I book a flight from Des Moines to Central America?

You are more likely to see cheaper flights to Central America from Des Moines when booking weeks ahead of your departure date. In general, you can expect to find flights to Central America for around $764 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Central America from Des Moines for as low as $669 on momondo.

Can stopping save me money on Des Moines to Central America flights?

You could potentially save up to 17% on your flight if you consider stops on a Des Moines to Central America flight.

Cheap Des Moines to Central America flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to Central America

Best Price Found	$287
Fastest flight time	6h 14m
Direct flights	None

The best one-way flight to Central America from Des Moines in the past 72 hours is $287. The best round-trip flight deal from Des Moines to Central America found on momondo in the last 72 hours is $583.

The fastest flight from Des Moines to Central America takes 6h 14m

There are no direct flights from Des Moines to Central America. There are no popular flight routes from Des Moines to Central America.

Search flight deals

Frequently asked questions about flying from Des Moines to Central America

When did momondo last update prices for flights from Des Moines Airport to Central America?
Prices for flights from Des Moines Airport to Central America are updated daily.
How many operators does momondo search for flights from Des Moines Airport to Central America?
As of October 2026, there are 3 operators available to choose from for flights from Des Moines Airport to Central America.
How old do you have to be to fly from Des Moines Airport to Central America?
Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Des Moines Airport to Central America.
What documentation or ID do you need to fly to Central America?
The travel and health documents you'll need for your trip to Central America may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Central America. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

Best airlines flying from Des Moines to Central America

Compare and see reviews for airlines that fly from Des Moines to Central America with momondo

Airline	Rating	Free Cancellation	Price
Delta	PriceFrom $301	Free Cancellation	Rating 7.8 8,661 reviews	Search Delta flights
American Airlines	PriceFrom $417	Free Cancellation	Rating 7.0 12,186 reviews	Search American Airlines flights
United Airlines	PriceFrom $461	Free Cancellation	Rating 7.3 10,404 reviews	Search United Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to Central America?

Finding the right flight to Central America from Des Moines is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Central America quick and easy, saving you time and money.

Can I find flights from Des Moines to Central America with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Central America from Des Moines with this policy.

How can momondo help me find flights from Des Moines to Central America?

momondo provides multiple filters to help you find the best flight to Central America from Des Moines. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Des Moines to Central America right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Des Moines to Central America flights. All you need is a valid email address and we will do the rest; it is that quick and easy.