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Cheap flights from Des Moines to Central America from $153

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Des Moines to Central America departing on 12/7. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Des Moines to Central America

Cheap round-trip flights

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American Airlines Logo
7:00 am - 10:30 pmDSM-SJO
15h 30m1 stop
American Airlines Logo
7:00 am - 10:27 pmSJO-DSM
15h 27m1 stop
$350American Airlines
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Thu, Feb 5 - Fri, Feb 13
Delta Logo
10:21 am - 10:15 pmDSM-SJO
11h 54m2 stops
Delta Logo
7:00 am - 9:19 pmSJO-DSM
14h 19m2 stops
$354Delta
Find Deal
Thu, Feb 5 - Fri, Feb 13
United Airlines Logo
8:00 am - 8:39 pmDSM-SJO
12h 39m2 stops
United Airlines Logo
6:30 am - 9:50 pmSJO-DSM
15h 20m2 stops
$374United Airlines
Find Deal
Sun, Feb 1 - Sat, Feb 7
American Airlines Logo
11:42 am - 10:30 pmDSM-SJO
10h 48m1 stop
American Airlines Logo
7:00 am - 6:24 pmSJO-DSM
11h 24m1 stop
$390American Airlines
Find Deal
Fri, Feb 6 - Sat, Feb 14
American Airlines Logo
7:40 am - 10:30 pmDSM-SJO
14h 50m2 stops
American Airlines Logo
7:45 am - 10:05 pmSJO-DSM
14h 20m2 stops
$394American Airlines
Find Deal
Fri, Feb 6 - Sat, Feb 14
Multiple Airlines Logo
9:03 pm - 1:50 pmDSM-GUA
16h 47m2 stops
Multiple Airlines Logo
1:38 pm - 8:29 amGUA-DSM
18h 51m1 stop
$411Multiple Airlines
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Sun, Nov 16 - Sat, Nov 22
United Airlines Logo
8:10 am - 8:39 pmDSM-SJO
12h 29m1 stop
United Airlines Logo
8:45 am - 10:20 pmSJO-DSM
13h 35m1 stop
$448United Airlines
Find Deal
Wed, Feb 11 - Mon, Feb 16
Delta Logo
5:45 am - 12:35 pmDSM-SAL
7h 50m1 stop
Delta Logo
2:00 pm - 10:24 pmSAL-DSM
7h 24m1 stop
$531Delta
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Sun, May 3 - Wed, May 6
Southwest Logo
5:45 am - 8:30 pmDSM-SJO
14h 45m2 stops
Southwest Logo
9:00 am - 9:35 pmSJO-DSM
12h 35m2 stops
$540Southwest
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Fri, Dec 12 - Wed, Dec 17
Southwest Logo
6:10 am - 7:30 pmDSM-SJO
13h 20m2 stops
Southwest Logo
9:40 am - 10:35 pmSJO-DSM
12h 55m2 stops
$607Southwest
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Wed, Feb 11 - Mon, Feb 16

American Airlines flights from Des Moines to Central America

Our best American Airlines deals on Des Moines to Central America flight tickets
American Airlines
Feb 5
DSM7:00 amDes Moines
15h 30m
1 stop
SJO10:30 pmSan José Juan Santamaria Intl
Feb 13
SJO7:00 amSan José Juan Santamaria Intl
15h 27m
1 stop
DSM10:27 pmDes Moines
$350
Find similar
American Airlines
Feb 6
DSM11:42 amDes Moines
10h 48m
1 stop
SJO10:30 pmSan José Juan Santamaria Intl
Feb 14
SJO7:00 amSan José Juan Santamaria Intl
11h 24m
1 stop
DSM6:24 pmDes Moines
$390
Find similar
American Airlines
Feb 6
DSM7:40 amDes Moines
14h 50m
2 stops
SJO10:30 pmSan José Juan Santamaria Intl
Feb 14
SJO7:45 amSan José Juan Santamaria Intl
14h 20m
2 stops
DSM10:05 pmDes Moines
$394
Find similar

Copa Airlines flights from Des Moines to Central America

Our best Copa Airlines deals on Des Moines to Central America flight tickets
Copa Airlines
Nov 11
DSM8:02 amDes Moines
14h 45m
2 stops
GUA10:47 pmGuatemala City La Aurora
Nov 19
GUA4:28 pmGuatemala City La Aurora
24h 57m
2 stops
DSM5:25 pmDes Moines
$502
Find similar
Copa Airlines
Nov 8
DSM8:02 amDes Moines
24h 17m
2 stops
SJO8:19 amSan José Juan Santamaria Intl
Nov 17
SJO6:07 pmSan José Juan Santamaria Intl
23h 18m
2 stops
DSM5:25 pmDes Moines
$728
Find similar
Copa Airlines
Nov 8
DSM8:02 amDes Moines
23h 31m
2 stops
SJO7:33 amSan José Juan Santamaria Intl
Nov 10
SJO6:07 pmSan José Juan Santamaria Intl
23h 18m
2 stops
DSM5:25 pmDes Moines
$740
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Des Moines to Central America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated November 5, 2025.
Use the filters below to find and compare flights from Des Moines to Central America that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Des MoinesSan José

DSM - SJO

DSMSJO

Des Moines

Thu 2/5

7:00 am-10:30 pm

1 stop15h 30m

San José Juan Santamaria Intl

Fri 2/13

7:00 am-10:27 pm

1 stop15h 27m

$350

Des MoinesSan José

DSM - SJO

DSMSJO

Des Moines

Thu 2/5

10:21 am-10:15 pm

2 stops11h 54m

San José Juan Santamaria Intl

Fri 2/13

7:00 am-9:19 pm

2 stops14h 19m

$354

Des MoinesSan José

DSM - SJO

DSMSJO

Des Moines

Sun 2/1

8:00 am-8:39 pm

2 stops12h 39m

San José Juan Santamaria Intl

Sat 2/7

6:30 am-9:50 pm

2 stops15h 20m

$374

Des MoinesSan José

DSM - SJO

DSMSJO

Des Moines

Fri 2/6

11:42 am-10:30 pm

1 stop10h 48m

San José Juan Santamaria Intl

Sat 2/14

7:00 am-6:24 pm

1 stop11h 24m

$390

Des MoinesSan José

DSM - SJO

DSMSJO

Des Moines

Fri 2/6

7:40 am-10:30 pm

2 stops14h 50m

San José Juan Santamaria Intl

Sat 2/14

7:45 am-10:05 pm

2 stops14h 20m

$394

Des MoinesGuatemala City

DSM - GUA

DSMGUA

Des Moines

Sun 11/16

9:03 pm-1:50 pm

2 stops16h 47m

Guatemala City La Aurora

Sat 11/22

1:38 pm-8:29 am

1 stop18h 51m

$411

Des MoinesSan José

DSM - SJO

DSMSJO

Des Moines

Wed 2/11

8:10 am-8:39 pm

1 stop12h 29m

San José Juan Santamaria Intl

Mon 2/16

8:45 am-10:20 pm

1 stop13h 35m

$448

Des MoinesSan Salvador

DSM - SAL

DSMSAL

Des Moines

Sun 5/3

5:45 am-12:35 pm

1 stop7h 50m

San Salvador El Salvador Intl

Wed 5/6

2:00 pm-10:24 pm

1 stop7h 24m

$531

Des MoinesSan José

DSM - SJO

DSMSJO

Des Moines

Fri 12/12

5:45 am-8:30 pm

2 stops14h 45m

San José Juan Santamaria Intl

Wed 12/17

9:00 am-9:35 pm

2 stops12h 35m

$540

Des MoinesSan José

DSM - SJO

DSMSJO

Des Moines

Wed 2/11

6:10 am-7:30 pm

2 stops13h 20m

San José Juan Santamaria Intl

Mon 2/16

9:40 am-10:35 pm

2 stops12h 55m

$607

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Des Moines to Central America

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Central America?

In general, August is the cheapest month to fly from Des Moines to Central America. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $577. If you don’t want to visit Central America in August, then you should wait until November to fly from Des Moines, when ticket prices are also cheap, with an average price of $601.

What is the cheapest day to depart on your flight to Central America?

The cheapest day to depart from Des Moines to Central America is on a Tuesday. Travelers who choose to depart for Central America on a Tuesday will often find tickets for as low as $517. On the other hand, Saturday is the most expensive day to depart from Des Moines because it is more convenient for both business and leisure travelers. As a result, prices tend to be around $762.

What is the cheapest time of day to depart on your flight to Central America?

Our data shows that the cheapest Des Moines to Central America flights are usually those with departure times in the afternoon. Our users have found flights to Central America in the afternoon for as low as $589. Try not to purchase tickets at noon because they tend to be around $736. Of course, these prices can vary depending on the time of year and what airport you fly to.

How far in advance should I book a flight to Central America?

You are more likely to see cheaper flights to Central America from Des Moines when booking week ahead of your departure date. In general, you can expect to find flights to Central America for around $687 when searching week out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Central America from Des Moines for as low as $400 on momondo.

Can stopping save me money on Des Moines to Central America flights?

You could potentially save up to 13% on your flight if you consider stops on a Des Moines to Central America flight.

Cheap Des Moines to Central America flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to Central America

Direct flights

None
There are no direct flights from Des Moines to Central America. There are no popular flight routes from Des Moines to Central America.
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  • When did momondo last update prices for flights from Des Moines Airport to Central America?

    Prices for flights from Des Moines Airport to Central America are updated daily.

  • How many operators does momondo search for flights from Des Moines Airport to Central America?

  • How old do you have to be to fly from Des Moines Airport to Central America?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Des Moines Airport to Central America.

  • What documentation or ID do you need to fly to Central America?

    The travel and health documents you'll need for your trip to Central America may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Central America. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

Best airlines flying from Des Moines to Central America

Compare and see reviews for airlines that fly from Des Moines to Central America with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $289Free CancellationRating
7.9
8,004 reviews
Search Delta flights
United AirlinesPriceFrom $414Free CancellationRating
7.4
9,002 reviews
Search United Airlines flights
American AirlinesPriceFrom $488Free CancellationRating
7.2
11,042 reviews
Search American Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to Central America?

Finding the right flight to Central America from Des Moines is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Central America quick and easy, saving you time and money.

Can I find flights from Des Moines to Central America with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Central America from Des Moines with this policy.

How can momondo help me find flights from Des Moines to Central America?

momondo provides multiple filters to help you find the best flight to Central America from Des Moines. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Des Moines to Central America right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Des Moines to Central America flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

An easier way to manage your Central America trip

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Find better results for your trip to Central America

Popular cities in Central America

Popular flights according to clicks in the last 7 days on momondo
Flights to San Joséfrom $144
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