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Cheap flights from Cleveland to Panama from $232

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Cleveland to Panama departing on 3/3. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Cleveland to Panama

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
7:18 pm - 12:22 pm
CLE
-
PTY
18h 04m2 stops
American Airlines Logo
1:55 pm - 11:45 am
PTY
-
CLE
20h 50m2 stops
$494American Airlines
Thu, Apr 2 - Fri, Apr 10
American Airlines Logo
6:17 pm - 12:22 pm
CLE
-
PTY
19h 05m1 stop
American Airlines Logo
1:55 pm - 11:45 am
PTY
-
CLE
20h 50m2 stops
$506American Airlines
Thu, Apr 2 - Fri, Apr 10
United Airlines Logo
12:14 pm - 8:02 pm
CLE
-
PTY
7h 48m1 stop
United Airlines Logo
8:55 am - 9:58 pm
PTY
-
CLE
13h 03m1 stop
$510United Airlines
Fri, Feb 6 - Wed, Feb 11
American Airlines Logo
4:44 pm - 1:27 pm
CLE
-
PTY
20h 43m2 stops
American Airlines Logo
2:27 pm - 10:00 am
PTY
-
CLE
19h 33m2 stops
$514American Airlines
Fri, Feb 6 - Wed, Feb 11
United Airlines Logo
3:05 pm - 4:12 pm
CLE
-
PTY
26h 07m1 stop
United Airlines Logo
3:30 pm - 11:18 am
PTY
-
CLE
18h 48m1 stop
$520United Airlines
Sun, Apr 5 - Fri, Apr 10
United Airlines Logo
6:00 am - 7:38 pm
CLE
-
PTY
13h 38m1 stop
United Airlines Logo
4:41 pm - 11:08 am
PTY
-
CLE
18h 27m1 stop
$530United Airlines
Mon, Feb 2 - Sat, Feb 7
American Airlines Logo
4:44 pm - 1:27 pm
CLE
-
PTY
20h 43m2 stops
American Airlines Logo
5:00 pm - 10:38 am
PTY
-
CLE
17h 38m2 stops
$534American Airlines
Mon, Feb 2 - Sat, Feb 7
United Airlines Logo
6:09 pm - 4:12 pm
CLE
-
PTY
23h 03m1 stop
United Airlines Logo
3:30 pm - 11:18 am
PTY
-
CLE
18h 48m1 stop
$541United Airlines
Fri, Apr 3 - Fri, Apr 10
American Airlines Logo
6:26 pm - 1:27 pm
CLE
-
PTY
19h 01m1 stop
American Airlines Logo
2:50 pm - 10:30 am
PTY
-
CLE
19h 40m2 stops
$546American Airlines
Mon, Feb 2 - Sat, Feb 28
Multiple Airlines Logo
7:10 am - 8:34 pm
CLE
-
PTY
13h 24m1 stop
Multiple Airlines Logo
5:50 pm - 10:59 pm
PTY
-
CLE
29h 09m2 stops
$547Multiple Airlines
Tue, Jan 13 - Tue, Jan 20

American Airlines flights from Cleveland to Panama

Our best American Airlines deals on Cleveland to Panama flight tickets
American Airlines
Apr 2
CLE7:18 pmCleveland Hopkins Intl
20h 04m
2 stops
PTY2:22 pmPanama City Tocumen Intl
Apr 10
PTY1:55 pmPanama City Tocumen Intl
20h 50m
2 stops
CLE11:45 amCleveland Hopkins Intl
$494
Find similar
American Airlines
Apr 2
CLE12:52 pmCleveland Hopkins Intl
26h 30m
1 stop
PTY2:22 pmPanama City Tocumen Intl
Apr 10
PTY1:55 pmPanama City Tocumen Intl
20h 50m
2 stops
CLE11:45 amCleveland Hopkins Intl
$506
Find similar
American Airlines
Feb 6
CLE4:44 pmCleveland Hopkins Intl
20h 43m
2 stops
PTY1:27 pmPanama City Tocumen Intl
Feb 11
PTY2:27 pmPanama City Tocumen Intl
19h 33m
2 stops
CLE10:00 amCleveland Hopkins Intl
$514
Find similar

United Airlines flights from Cleveland to Panama

Our best United Airlines deals on Cleveland to Panama flight tickets
United Airlines
Mar 30
CLE7:12 pmCleveland Hopkins Intl
9h 52m
1 stop
PTY4:04 amPanama City Tocumen Intl
Apr 7
PTY10:55 pmPanama City Tocumen Intl
9h 41m
1 stop
CLE9:36 amCleveland Hopkins Intl
$490
Find similar
United Airlines
Apr 2
CLE9:59 amCleveland Hopkins Intl
10h 32m
1 stop
PTY7:31 pmPanama City Tocumen Intl
Apr 10
PTY3:30 pmPanama City Tocumen Intl
18h 48m
1 stop
CLE11:18 amCleveland Hopkins Intl
$510
Find similar
United Airlines
Mar 30
CLE7:12 pmCleveland Hopkins Intl
9h 52m
1 stop
PTY4:04 amPanama City Tocumen Intl
Apr 8
PTY7:55 amPanama City Tocumen Intl
12h 59m
1 stop
CLE9:54 pmCleveland Hopkins Intl
$515
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Cleveland to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated December 18, 2025.
Use the filters below to find and compare flights from Cleveland to Panama that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

ClevelandPanama City

CLE - PTY

CLEPTY

Cleveland Hopkins Intl

Thu 4/2

7:18 pm-12:22 pm

2 stops18h 04m

Panama City Tocumen Intl

Fri 4/10

1:55 pm-11:45 am

2 stops20h 50m

$494

ClevelandPanama City

CLE - PTY

CLEPTY

Cleveland Hopkins Intl

Thu 4/2

6:17 pm-12:22 pm

1 stop19h 05m

Panama City Tocumen Intl

Fri 4/10

1:55 pm-11:45 am

2 stops20h 50m

$506

ClevelandPanama City

CLE - PTY

CLEPTY

Cleveland Hopkins Intl

Fri 2/6

12:14 pm-8:02 pm

1 stop7h 48m

Panama City Tocumen Intl

Wed 2/11

8:55 am-9:58 pm

1 stop13h 03m

$510

ClevelandPanama City

CLE - PTY

CLEPTY

Cleveland Hopkins Intl

Fri 2/6

4:44 pm-1:27 pm

2 stops20h 43m

Panama City Tocumen Intl

Wed 2/11

2:27 pm-10:00 am

2 stops19h 33m

$514

ClevelandPanama City

CLE - PTY

CLEPTY

Cleveland Hopkins Intl

Sun 4/5

3:05 pm-4:12 pm

1 stop26h 07m

Panama City Tocumen Intl

Fri 4/10

3:30 pm-11:18 am

1 stop18h 48m

$520

ClevelandPanama City

CLE - PTY

CLEPTY

Cleveland Hopkins Intl

Mon 2/2

6:00 am-7:38 pm

1 stop13h 38m

Panama City Tocumen Intl

Sat 2/7

4:41 pm-11:08 am

1 stop18h 27m

$530

ClevelandPanama City

CLE - PTY

CLEPTY

Cleveland Hopkins Intl

Mon 2/2

4:44 pm-1:27 pm

2 stops20h 43m

Panama City Tocumen Intl

Sat 2/7

5:00 pm-10:38 am

2 stops17h 38m

$534

ClevelandPanama City

CLE - PTY

CLEPTY

Cleveland Hopkins Intl

Fri 4/3

6:09 pm-4:12 pm

1 stop23h 03m

Panama City Tocumen Intl

Fri 4/10

3:30 pm-11:18 am

1 stop18h 48m

$541

ClevelandPanama City

CLE - PTY

CLEPTY

Cleveland Hopkins Intl

Mon 2/2

6:26 pm-1:27 pm

1 stop19h 01m

Panama City Tocumen Intl

Sat 2/28

2:50 pm-10:30 am

2 stops19h 40m

$546

ClevelandPanama City

CLE - PTY

CLEPTY

Cleveland Hopkins Intl

Tue 1/13

7:10 am-8:34 pm

1 stop13h 24m

Panama City Tocumen Intl

Tue 1/20

5:50 pm-10:59 pm

2 stops29h 09m

$547

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 11 resultsSorted by cheapest first
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See travel insights to Panama from

How to get the cheapest flight ticket from Cleveland to Panama

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Panama?

The month of November is, on average, the cheapest month to fly to Panama from Cleveland, with most prices found around $429. If you don’t want to visit Panama in November, then you should wait until September to fly from Cleveland, when ticket prices are also cheap, with an average price of $506.

What is the cheapest day to depart on your flight to Panama?

According to our data, Friday is the cheapest day to fly to Panama from Cleveland. The lowest ticket price found for a Friday departure recently was $513. Keep in mind that prices can always vary depending on your route and whether or not you are flying domestic or international. When flying out on a Sunday, the most expensive travel day of the week, you can expect to see flight prices from Cleveland to Panama for around $744.

What is the cheapest time of day to depart on your flight to Panama?

In the morning is the cheapest time of day to fly from Cleveland to Panama when you can find flight prices for as low as $598. Flying to Panama in the morning is an ideal time because this is during off-peak travel hours. In the afternoon is when there is more demand to fly to Panama, so prices are often more expensive at around $746 per ticket.

Cheap Cleveland to Panama flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Cleveland to Panama

Fastest flight time

7h 48m

Direct flights

None
The fastest flight from Cleveland to Panama takes 7h 48m
There are no direct flights from Cleveland to Panama. There are no popular flight routes from Cleveland to Panama.
Search flight deals

  • When did momondo last update prices for flights from Cleveland Hopkins Intl Airport to Panama?

    Prices for flights from Cleveland Hopkins Intl Airport to Panama are refreshed on a daily basis.

  • How many operators does momondo search for flights from Cleveland Hopkins Intl Airport to Panama?

  • How old do you have to be to fly from Cleveland Hopkins Intl Airport to Panama?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Cleveland Hopkins Intl Airport to Panama.

  • What documentation or ID do you need to fly to Panama?

    The travel and health documents you'll need for your trip to Panama may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Panama. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

Best airlines flying from Cleveland to Panama

Compare and see reviews for airlines that fly from Cleveland to Panama with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $389Free CancellationRating
7.9
8,005 reviews
Search Delta flights
American AirlinesPriceFrom $390Free CancellationRating
7.2
11,054 reviews
Search American Airlines flights
United AirlinesPriceFrom $469Free CancellationRating
7.4
9,091 reviews
Search United Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Cleveland to Panama?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Cleveland to Panama. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Cleveland to Panama with flexible booking policies on momondo?

All flight searches from Cleveland to Panama on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Cleveland to Panama?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Cleveland to Panama.

I’m not ready to book a flight from Cleveland to Panama right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Cleveland to Panama flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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