Latest deals
Insights
FAQs
Reviews
Price Alerts

Cheap flights from Cleveland to Panama from $248

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Cleveland to Panama departing on 4/22. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

Discover deals from 900+ travel sites with momondo.

Save money when you book flights with momondo

Big names and deals

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Price Alerts

Not ready to book? to track prices.
Search flight deals

Find the cheapest flights from Cleveland to Panama

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
5:35 pm - 1:05 am
CLE
-
PTY
32h 30m
2 stops
Multiple Airlines Logo
9:33 pm - 10:03 am
PTY
-
CLE
11h 30m
1 stop
$469Multiple Airlines
Wed, Apr 15 - Wed, Apr 22
Multiple Airlines Logo
8:35 pm - 8:06 am
CLE
-
PTY
12h 31m
1 stop
Multiple Airlines Logo
12:33 pm - 10:34 pm
PTY
-
CLE
9h 01m
1 stop
$482Multiple Airlines
Thu, Mar 12 - Thu, Mar 19
Multiple Airlines Logo
7:30 am - 8:19 pm
CLE
-
PTY
13h 49m
1 stop
Multiple Airlines Logo
12:03 pm - 11:28 pm
PTY
-
CLE
10h 25m
1 stop
$496Multiple Airlines
Wed, Mar 11 - Wed, Mar 18
Multiple Airlines Logo
1:38 pm - 8:34 pm
CLE
-
PTY
7h 56m
1 stop
Multiple Airlines Logo
10:26 am - 11:19 pm
PTY
-
CLE
11h 53m
1 stop
$506Multiple Airlines
Tue, Mar 31 - Tue, Apr 7
Multiple Airlines Logo
6:05 pm - 8:06 am
CLE
-
PTY
15h 01m
2 stops
Multiple Airlines Logo
9:33 pm - 12:26 pm
PTY
-
CLE
13h 53m
1 stop
$509Multiple Airlines
Wed, Apr 1 - Wed, Apr 8
Multiple Airlines Logo
11:13 am - 8:35 pm
CLE
-
PTY
10h 22m
1 stop
Multiple Airlines Logo
9:33 pm - 11:14 pm
PTY
-
CLE
24h 41m
2 stops
$512Multiple Airlines
Thu, Apr 23 - Mon, Apr 27
Multiple Airlines Logo
4:38 pm - 8:06 am
CLE
-
PTY
16h 28m
1 stop
Multiple Airlines Logo
3:10 pm - 10:03 am
PTY
-
CLE
17h 53m
2 stops
$516Multiple Airlines
Sun, Apr 12 - Sun, Apr 19
United Airlines Logo
6:00 am - 2:14 pm
CLE
-
PTY
9h 14m
1 stop
United Airlines Logo
7:55 am - 9:55 pm
PTY
-
CLE
13h 00m
1 stop
$521United Airlines
Mon, May 11 - Mon, May 18
American Airlines Logo
1:32 pm - 12:46 pm
CLE
-
PTY
24h 14m
2 stops
American Airlines Logo
1:14 pm - 11:49 pm
PTY
-
CLE
9h 35m
1 stop
$525American Airlines
Wed, Apr 29 - Wed, May 27
Multiple Airlines Logo
3:13 pm - 8:50 am
CLE
-
PTY
17h 37m
2 stops
Multiple Airlines Logo
10:25 am - 7:31 pm
PTY
-
CLE
8h 06m
1 stop
$527Multiple Airlines
Mon, Mar 2 - Thu, Mar 12

United Airlines flights from Cleveland to Panama

Our best United Airlines deals on Cleveland to Panama flight tickets
United Airlines
May 11
CLE6:00 amCleveland Hopkins Intl
9h 14m
1 stop
PTY2:14 pmPanama City Tocumen Intl
May 18
PTY7:55 amPanama City Tocumen Intl
13h 00m
1 stop
CLE9:55 pmCleveland Hopkins Intl
$521
United Airlines
Apr 24
CLE9:58 amCleveland Hopkins Intl
10h 33m
1 stop
PTY7:31 pmPanama City Tocumen Intl
Apr 27
PTY10:55 pmPanama City Tocumen Intl
10h 17m
1 stop
CLE10:12 amCleveland Hopkins Intl
$541
United Airlines
Apr 9
CLE9:58 amCleveland Hopkins Intl
10h 33m
1 stop
PTY7:31 pmPanama City Tocumen Intl
Apr 12
PTY3:30 pmPanama City Tocumen Intl
29h 25m
1 stop
CLE9:55 pmCleveland Hopkins Intl
$552

American Airlines flights from Cleveland to Panama

Our best American Airlines deals on Cleveland to Panama flight tickets
American Airlines
Apr 29
CLE6:49 pmCleveland Hopkins Intl
18h 57m
2 stops
PTY12:46 pmPanama City Tocumen Intl
May 27
PTY1:14 pmPanama City Tocumen Intl
23h 09m
2 stops
CLE1:23 pmCleveland Hopkins Intl
$525
American Airlines
May 11
CLE8:44 pmCleveland Hopkins Intl
17h 02m
2 stops
PTY12:46 pmPanama City Tocumen Intl
May 18
PTY1:49 pmPanama City Tocumen Intl
9h 10m
1 stop
CLE11:59 pmCleveland Hopkins Intl
$545
American Airlines
Apr 1
CLE5:35 amCleveland Hopkins Intl
10h 26m
2 stops
PTY3:01 pmPanama City Tocumen Intl
Apr 8
PTY1:49 pmPanama City Tocumen Intl
19h 33m
2 stops
CLE10:22 amCleveland Hopkins Intl
$550

momondo Fare Finder

 
Customize your flight search to find flights from Cleveland to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated February 16, 2026.
Use the filters below to find and compare flights from Cleveland to Panama that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

ClevelandPanama City

CLE - PTY

CLEPTY

Cleveland Hopkins Intl

Wed 4/15

5:35 pm-1:05 am

2 stops32h 30m

Panama City Tocumen Intl

Wed 4/22

9:33 pm-10:03 am

1 stop11h 30m

$469

ClevelandPanama City

CLE - PTY

CLEPTY

Cleveland Hopkins Intl

Thu 3/12

8:35 pm-8:06 am

1 stop12h 31m

Panama City Tocumen Intl

Thu 3/19

12:33 pm-10:34 pm

1 stop9h 01m

$482

ClevelandPanama City

CLE - PTY

CLEPTY

Cleveland Hopkins Intl

Wed 3/11

7:30 am-8:19 pm

1 stop13h 49m

Panama City Tocumen Intl

Wed 3/18

12:03 pm-11:28 pm

1 stop10h 25m

$496

ClevelandPanama City

CLE - PTY

CLEPTY

Cleveland Hopkins Intl

Tue 3/31

1:38 pm-8:34 pm

1 stop7h 56m

Panama City Tocumen Intl

Tue 4/7

10:26 am-11:19 pm

1 stop11h 53m

$506

ClevelandPanama City

CLE - PTY

CLEPTY

Cleveland Hopkins Intl

Wed 4/1

6:05 pm-8:06 am

2 stops15h 01m

Panama City Tocumen Intl

Wed 4/8

9:33 pm-12:26 pm

1 stop13h 53m

$509

ClevelandPanama City

CLE - PTY

CLEPTY

Cleveland Hopkins Intl

Thu 4/23

11:13 am-8:35 pm

1 stop10h 22m

Panama City Tocumen Intl

Mon 4/27

9:33 pm-11:14 pm

2 stops24h 41m

$512

ClevelandPanama City

CLE - PTY

CLEPTY

Cleveland Hopkins Intl

Sun 4/12

4:38 pm-8:06 am

1 stop16h 28m

Panama City Tocumen Intl

Sun 4/19

3:10 pm-10:03 am

2 stops17h 53m

$516

ClevelandPanama City

CLE - PTY

CLEPTY

Cleveland Hopkins Intl

Mon 5/11

6:00 am-2:14 pm

1 stop9h 14m

Panama City Tocumen Intl

Mon 5/18

7:55 am-9:55 pm

1 stop13h 00m

$521

ClevelandPanama City

CLE - PTY

CLEPTY

Cleveland Hopkins Intl

Wed 4/29

1:32 pm-12:46 pm

2 stops24h 14m

Panama City Tocumen Intl

Wed 5/27

1:14 pm-11:49 pm

1 stop9h 35m

$525

ClevelandPanama City

CLE - PTY

CLEPTY

Cleveland Hopkins Intl

Mon 3/2

3:13 pm-8:50 am

2 stops17h 37m

Panama City Tocumen Intl

Thu 3/12

10:25 am-7:31 pm

1 stop8h 06m

$527

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
1
2

See travel insights to Panama from

How to get the cheapest flight ticket from Cleveland to Panama

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Panama?

The month of November is, on average, the cheapest month to fly to Panama from Cleveland, with most prices found around $429. If you don’t want to visit Panama in November, then you should wait until September to fly from Cleveland, when ticket prices are also cheap, with an average price of $506.

Cheap Cleveland to Panama flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Cleveland to Panama

Fastest flight time

7h 50m

Direct flights

None
The fastest flight from Cleveland to Panama takes 7h 50m
There are no direct flights from Cleveland to Panama. There are no popular flight routes from Cleveland to Panama.
Search flight deals

  • When did momondo last update prices for flights from Cleveland Hopkins Intl Airport to Panama?

    Prices for flights from Cleveland Hopkins Intl Airport to Panama are refreshed on a daily basis.

  • How many operators does momondo search for flights from Cleveland Hopkins Intl Airport to Panama?

  • How old do you have to be to fly from Cleveland Hopkins Intl Airport to Panama?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Cleveland Hopkins Intl Airport to Panama.

  • What documentation or ID do you need to fly to Panama?

    The travel and health documents you'll need for your trip to Panama may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Panama. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

Best airlines flying from Cleveland to Panama

Compare and see reviews for airlines that fly from Cleveland to Panama with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $382Free CancellationRating
7.9
8,204 reviews
Search Delta flights
American AirlinesPriceFrom $390Free CancellationRating
7.2
11,292 reviews
Search American Airlines flights
United AirlinesPriceFrom $489Free CancellationRating
7.4
9,299 reviews
Search United Airlines flights
Copa AirlinesPriceFrom $701Free CancellationRating
7.5
1,555 reviews
Search Copa Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Cleveland to Panama?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Cleveland to Panama. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Cleveland to Panama with flexible booking policies on momondo?

All flight searches from Cleveland to Panama on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Cleveland to Panama?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Cleveland to Panama.

I’m not ready to book a flight from Cleveland to Panama right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Cleveland to Panama flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

An easier way to manage your Panama trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
Start using Trips
Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.
1 adult
Wed 3/18
Wed 3/25
By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to Panama

Popular cities in Panama

Popular flights according to clicks in the last 7 days on momondo
Flights to Panama Cityfrom $309
Flights to Bocas del Torofrom $737
Flights to Davidfrom $481
Flights to Changuinola