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Cheap flights from Cleveland to Panama from $170

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Cleveland to Panama departing on 10/20. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Cleveland to Panama

Cheap round-trip flights

Multiple Airlines Logo
7:00 am - 7:46 pmCLE-PTY
13h 46m1 stop
Multiple Airlines Logo
8:57 am - 10:37 pmPTY-CLE
13h 40m1 stop
$444Multiple Airlines
Find Deal
Fri, Oct 31 - Fri, Nov 7
United Airlines Logo
6:00 am - 5:07 pmCLE-PTY
11h 07m1 stop
United Airlines Logo
8:55 am - 9:58 pmPTY-CLE
13h 03m1 stop
$489United Airlines
Find Deal
Thu, Jan 29 - Mon, Feb 2
American Airlines Logo
6:07 am - 3:35 pmCLE-PTY
9h 28m1 stop
American Airlines Logo
4:40 pm - 9:59 amPTY-CLE
17h 19m2 stops
$494American Airlines
Find Deal
Thu, Jan 29 - Tue, Feb 3
Delta Logo
10:17 am - 2:12 pmCLE-PTY
27h 55m1 stop
Delta Logo
3:37 pm - 9:12 amPTY-CLE
17h 35m1 stop
$498Delta
Find Deal
Sun, Nov 16 - Thu, Nov 20
United Airlines Logo
6:00 pm - 2:45 pmCLE-PTY
20h 45m1 stop
United Airlines Logo
10:00 am - 8:20 pmPTY-CLE
10h 20m1 stop
$500United Airlines
Find Deal
Sun, Nov 16 - Thu, Nov 20
Delta Logo
7:05 am - 7:59 pmCLE-PTY
12h 54m1 stop
Delta Logo
3:37 pm - 12:44 amPTY-CLE
9h 07m1 stop
$509Delta
Find Deal
Sat, Nov 15 - Wed, Nov 19
American Airlines Logo
8:35 pm - 1:49 pmCLE-PTY
17h 14m2 stops
American Airlines Logo
2:43 pm - 8:47 amPTY-CLE
18h 04m2 stops
$514American Airlines
Find Deal
Sun, Nov 16 - Thu, Nov 20
United Airlines Logo
2:45 pm - 7:38 pmCLE-PTY
28h 53m1 stop
United Airlines Logo
4:41 pm - 11:08 amPTY-CLE
18h 27m1 stop
$520United Airlines
Find Deal
Sun, Jan 11 - Sat, Jan 17
Delta Logo
7:05 am - 12:56 pmCLE-PTY
6h 51m1 stop
Delta Logo
2:21 pm - 11:21 pmPTY-CLE
8h 00m1 stop
$529Delta
Find Deal
Wed, Oct 15 - Thu, Oct 16
Copa Airlines Logo
6:00 am - 8:27 pmCLE-PTY
14h 27m1 stop
Copa Airlines Logo
9:18 pm - 9:41 amPTY-CLE
12h 23m1 stop
$701Copa Airlines
Find Deal
Fri, Nov 28 - Sun, Nov 30

American Airlines flights from Cleveland to Panama

Our best American Airlines deals on Cleveland to Panama flight tickets
American Airlines
Jan 29
CLE6:07 amCleveland Hopkins Intl
9h 28m
1 stop
PTY3:35 pmPanama City Tocumen Intl
Feb 3
PTY4:40 pmPanama City Tocumen Intl
17h 19m
2 stops
CLE9:59 amCleveland Hopkins Intl
$494
Find similar
American Airlines
Nov 16
CLE8:35 pmCleveland Hopkins Intl
17h 14m
2 stops
PTY1:49 pmPanama City Tocumen Intl
Nov 20
PTY2:43 pmPanama City Tocumen Intl
18h 04m
2 stops
CLE8:47 amCleveland Hopkins Intl
$514
Find similar
American Airlines
Jan 11
CLE6:07 amCleveland Hopkins Intl
7h 03m
1 stop
PTY1:10 pmPanama City Tocumen Intl
Jan 17
PTY4:40 pmPanama City Tocumen Intl
16h 10m
2 stops
CLE8:50 amCleveland Hopkins Intl
$534
Find similar

United Airlines flights from Cleveland to Panama

Our best United Airlines deals on Cleveland to Panama flight tickets
United Airlines
Jan 29
CLE6:00 amCleveland Hopkins Intl
11h 07m
1 stop
PTY5:07 pmPanama City Tocumen Intl
Feb 2
PTY8:55 amPanama City Tocumen Intl
13h 03m
1 stop
CLE9:58 pmCleveland Hopkins Intl
$489
Find similar
United Airlines
Nov 16
CLE6:00 pmCleveland Hopkins Intl
20h 45m
1 stop
PTY2:45 pmPanama City Tocumen Intl
Nov 20
PTY10:00 amPanama City Tocumen Intl
10h 20m
1 stop
CLE8:20 pmCleveland Hopkins Intl
$500
Find similar
United Airlines
Jan 11
CLE2:45 pmCleveland Hopkins Intl
28h 53m
1 stop
PTY7:38 pmPanama City Tocumen Intl
Jan 17
PTY4:41 pmPanama City Tocumen Intl
18h 27m
1 stop
CLE11:08 amCleveland Hopkins Intl
$520
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Cleveland to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated September 17, 2025.
Use the filters below to find and compare flights from Cleveland to Panama that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

ClevelandPanama City

CLE - PTY

CLEPTY

Cleveland Hopkins Intl

Fri 10/31

7:00 am-7:46 pm

1 stop13h 46m

Panama City Tocumen Intl

Fri 11/7

8:57 am-10:37 pm

1 stop13h 40m

$444

ClevelandPanama City

CLE - PTY

CLEPTY

Cleveland Hopkins Intl

Thu 1/29

6:00 am-5:07 pm

1 stop11h 07m

Panama City Tocumen Intl

Mon 2/2

8:55 am-9:58 pm

1 stop13h 03m

$489

ClevelandPanama City

CLE - PTY

CLEPTY

Cleveland Hopkins Intl

Thu 1/29

6:07 am-3:35 pm

1 stop9h 28m

Panama City Tocumen Intl

Tue 2/3

4:40 pm-9:59 am

2 stops17h 19m

$494

ClevelandPanama City

CLE - PTY

CLEPTY

Cleveland Hopkins Intl

Sun 11/16

10:17 am-2:12 pm

1 stop27h 55m

Panama City Tocumen Intl

Thu 11/20

3:37 pm-9:12 am

1 stop17h 35m

$498

ClevelandPanama City

CLE - PTY

CLEPTY

Cleveland Hopkins Intl

Sun 11/16

6:00 pm-2:45 pm

1 stop20h 45m

Panama City Tocumen Intl

Thu 11/20

10:00 am-8:20 pm

1 stop10h 20m

$500

ClevelandPanama City

CLE - PTY

CLEPTY

Cleveland Hopkins Intl

Sat 11/15

7:05 am-7:59 pm

1 stop12h 54m

Panama City Tocumen Intl

Wed 11/19

3:37 pm-12:44 am

1 stop9h 07m

$509

ClevelandPanama City

CLE - PTY

CLEPTY

Cleveland Hopkins Intl

Sun 11/16

8:35 pm-1:49 pm

2 stops17h 14m

Panama City Tocumen Intl

Thu 11/20

2:43 pm-8:47 am

2 stops18h 04m

$514

ClevelandPanama City

CLE - PTY

CLEPTY

Cleveland Hopkins Intl

Sun 1/11

2:45 pm-7:38 pm

1 stop28h 53m

Panama City Tocumen Intl

Sat 1/17

4:41 pm-11:08 am

1 stop18h 27m

$520

ClevelandPanama City

CLE - PTY

CLEPTY

Cleveland Hopkins Intl

Wed 10/15

7:05 am-12:56 pm

1 stop6h 51m

Panama City Tocumen Intl

Thu 10/16

2:21 pm-11:21 pm

1 stop8h 00m

$529

ClevelandPanama City

CLE - PTY

CLEPTY

Cleveland Hopkins Intl

Fri 11/28

6:00 am-8:27 pm

1 stop14h 27m

Panama City Tocumen Intl

Sun 11/30

9:18 pm-9:41 am

1 stop12h 23m

$701

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Panama from

How to get the cheapest flight ticket from Cleveland to Panama

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Panama?

The month of November is, on average, the cheapest month to fly to Panama from Cleveland, with most prices found around $489. If you don’t want to visit Panama in November, then you should wait until September to fly from Cleveland, when ticket prices are also cheap, with an average price of $506.

What is the cheapest day to depart on your flight to Panama?

According to our data, Friday is the cheapest day to fly to Panama from Cleveland. The lowest ticket price found for a Friday departure recently was $513. Keep in mind that prices can always vary depending on your route and whether or not you are flying domestic or international. When flying out on a Sunday, the most expensive travel day of the week, you can expect to see flight prices from Cleveland to Panama for around $744.

What is the cheapest time of day to depart on your flight to Panama?

In the morning is the cheapest time of day to fly from Cleveland to Panama when you can find flight prices for as low as $598. Flying to Panama in the morning is an ideal time because this is during off-peak travel hours. In the afternoon is when there is more demand to fly to Panama, so prices are often more expensive at around $746 per ticket.

How far in advance should I book a flight to Panama?

You are more likely to see cheaper flights to Panama from Cleveland when booking weeks ahead of your departure date. In general, you can expect to find flights to Panama for around $602 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Panama from Cleveland for as low as $415 on momondo.

Cheap Cleveland to Panama flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Cleveland to Panama

Direct flights

None
There are no direct flights from Cleveland to Panama. There are no popular flight routes from Cleveland to Panama.
Search flight deals

  • When did momondo last update prices for flights from Cleveland Hopkins Intl Airport to Panama?

    Prices for flights from Cleveland Hopkins Intl Airport to Panama are refreshed on a daily basis.

  • How many operators does momondo search for flights from Cleveland Hopkins Intl Airport to Panama?

  • How old do you have to be to fly from Cleveland Hopkins Intl Airport to Panama?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Cleveland Hopkins Intl Airport to Panama.

  • What documentation or ID do you need to fly to Panama?

    The travel and health documents you'll need for your trip to Panama may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Panama. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

Best airlines flying from Cleveland to Panama

Compare and see reviews for airlines that fly from Cleveland to Panama with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $389Free CancellationRating
7.9
7,961 reviews
Search Delta flights
American AirlinesPriceFrom $469Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights
United AirlinesPriceFrom $469Free CancellationRating
7.4
8,926 reviews
Search United Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Cleveland to Panama?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Cleveland to Panama. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Cleveland to Panama with flexible booking policies on momondo?

All flight searches from Cleveland to Panama on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Cleveland to Panama?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Cleveland to Panama.

I’m not ready to book a flight from Cleveland to Panama right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Cleveland to Panama flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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