What is the cheapest airline that flies from Cleveland Hopkins Intl to Panama?

American Airlines is the most popular carrier operating from Cleveland Hopkins Intl to Panama

What airlines fly to Panama?

American Airlines, Copa Airlines and Delta are the top three most popular airlines that fly to Panama from Cleveland according to our data. American Airlines is the first choice among our users, with 27% of people opting to fly with this airline when traveling to Panama. Keep in mind that there are 4 different airlines that fly to Panama on a routine basis, so you have a few additional options to choose from.

When did momondo last update prices for flights from Cleveland Hopkins Intl Airport to Panama?

Prices for flights from Cleveland Hopkins Intl Airport to Panama are refreshed on a daily basis.

How many operators does momondo search for flights from Cleveland Hopkins Intl Airport to Panama?

As of October 2026, there are 4 operators available to choose from for flights from Cleveland Hopkins Intl Airport to Panama.

How old do you have to be to fly from Cleveland Hopkins Intl Airport to Panama?

The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Cleveland Hopkins Intl Airport to Panama.

What documentation or ID do you need to fly to Panama?

The travel and health documents you'll need for your trip to Panama may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Panama. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

$348 Cheap Flights from Cleveland to Panama in 2026/27

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Cleveland to Panama

Round-trip

One-way

Last minute

Cheap round-trip flights

Enter your travel dates to find the best prices.

6:00 am - 5:12 pmCLE Cleveland Hopkins Intl-PTY Panama City Tocumen Intl

11h 12m1 stop Houston George Bush Intcntl

8:55 am - 6:23 pmPTY Panama City Tocumen Intl-CLE Cleveland Hopkins Intl

9h 28m1 stop Houston George Bush Intcntl

$607United Airlines

Wed, Feb 3 - Wed, Feb 17

8:25 am - 8:02 pmCLE Cleveland Hopkins Intl-PTY Panama City Tocumen Intl

11h 37m1 stop Newark

10:00 am - 10:08 pmPTY Panama City Tocumen Intl-CLE Cleveland Hopkins Intl

12h 08m1 stop Newark

$607United Airlines

Thu, Dec 10 - Tue, Dec 15

5:59 pm - 1:26 pmCLE Cleveland Hopkins Intl-PTY Panama City Tocumen Intl

19h 27m2 stops New York LaGuardia Miami

2:26 pm - 9:32 amPTY Panama City Tocumen Intl-CLE Cleveland Hopkins Intl

19h 06m2 stops Miami Chicago O'Hare Intl

$611American Airlines

Thu, Feb 4 - Tue, Feb 9

6:37 pm - 1:26 pmCLE Cleveland Hopkins Intl-PTY Panama City Tocumen Intl

18h 49m2 stops Charlotte Douglas Miami

2:26 pm - 11:59 pmPTY Panama City Tocumen Intl-CLE Cleveland Hopkins Intl

9h 33m1 stop Miami

$611American Airlines

Thu, Feb 4 - Tue, Feb 9

6:00 am - 1:00 pmCLE Cleveland Hopkins Intl-PTY Panama City Tocumen Intl

8h 00m1 stop Atlanta Hartsfield-Jackson

2:25 pm - 12:35 amPTY Panama City Tocumen Intl-CLE Cleveland Hopkins Intl

9h 10m1 stop Atlanta Hartsfield-Jackson

$654Delta

Tue, Mar 23 - Thu, Mar 25

6:00 am - 1:00 pmCLE Cleveland Hopkins Intl-PTY Panama City Tocumen Intl

8h 00m1 stop Atlanta Hartsfield-Jackson

2:25 pm - 12:35 amPTY Panama City Tocumen Intl-CLE Cleveland Hopkins Intl

9h 10m1 stop Atlanta Hartsfield-Jackson

$654Delta

Mon, Mar 22 - Thu, Mar 25

7:53 am - 8:02 pmCLE Cleveland Hopkins Intl-PTY Panama City Tocumen Intl

12h 09m1 stop Newark

4:41 pm - 11:18 amPTY Panama City Tocumen Intl-CLE Cleveland Hopkins Intl

18h 37m1 stop Houston George Bush Intcntl

$656Copa Airlines

Wed, Nov 25 - Mon, Nov 30

5:45 am - 8:02 pmCLE Cleveland Hopkins Intl-PTY Panama City Tocumen Intl

14h 17m1 stop Newark

10:00 am - 9:54 pmPTY Panama City Tocumen Intl-CLE Cleveland Hopkins Intl

11h 54m1 stop Newark

$691Copa Airlines

Thu, Dec 10 - Fri, Dec 18

12:57 pm - 6:35 amCLE Cleveland Hopkins Intl-PTY Panama City Tocumen Intl

17h 38m2 stops Atlanta Hartsfield-Jackson Miami

9:48 pm - 12:28 amPTY Panama City Tocumen Intl-CLE Cleveland Hopkins Intl

26h 40m1 stop Miami

$754Multiple Airlines

Sun, Dec 13 - Thu, Dec 17

7:00 am - 5:15 pmCLE Cleveland Hopkins Intl-PTY Panama City Tocumen Intl

34h 15m3 stops Atlanta Hartsfield-Jackson Miami Bogotá El Dorado

4:10 pm - 12:16 pmPTY Panama City Tocumen Intl-CLE Cleveland Hopkins Intl

20h 06m3 stops Bogotá El Dorado Miami Atlanta Hartsfield-Jackson

$761Multiple Airlines

Thu, Nov 5 - Tue, Nov 10

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American Airlines flights from Cleveland to Panama

Our best American Airlines deals on Cleveland to Panama flight tickets

American Airlines

Dec 1

CLE7:30 pmCleveland Hopkins Intl

18h 43m

2 stops

PTY2:13 pmPanama City Tocumen Intl

Dec 8

PTY3:13 pmPanama City Tocumen Intl

21h 08m

2 stops

CLE12:21 pmCleveland Hopkins Intl

$611

American Airlines

Feb 22

CLE6:46 pmCleveland Hopkins Intl

20h 28m

2 stops

PTY3:14 pmPanama City Tocumen Intl

Feb 26

PTY2:39 pmPanama City Tocumen Intl

9h 11m

1 stop

CLE11:50 pmCleveland Hopkins Intl

$612

American Airlines

Feb 3

CLE7:00 pmCleveland Hopkins Intl

18h 26m

1 stop

PTY1:26 pmPanama City Tocumen Intl

Feb 17

PTY2:39 pmPanama City Tocumen Intl

18h 23m

2 stops

CLE9:02 amCleveland Hopkins Intl

$617

United Airlines flights from Cleveland to Panama

Our best United Airlines deals on Cleveland to Panama flight tickets

United Airlines

Mar 17

CLE8:00 amCleveland Hopkins Intl

12h 02m

1 stop

PTY7:02 pmPanama City Tocumen Intl

Mar 23

PTY9:30 amPanama City Tocumen Intl

11h 27m

1 stop

CLE9:57 pmCleveland Hopkins Intl

$607

United Airlines

Nov 25

CLE7:53 amCleveland Hopkins Intl

12h 09m

1 stop

PTY8:02 pmPanama City Tocumen Intl

Nov 30

PTY8:55 amPanama City Tocumen Intl

26h 23m

1 stop

CLE11:18 amCleveland Hopkins Intl

$619

United Airlines

Mar 21

CLE4:00 pmCleveland Hopkins Intl

13h 10m

1 stop

PTY4:10 amPanama City Tocumen Intl

Mar 30

PTY10:55 pmPanama City Tocumen Intl

11h 03m

1 stop

CLE10:58 amCleveland Hopkins Intl

$641

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

ClevelandPanama City

CLE Cleveland Hopkins Intl - PTY Panama City Tocumen Intl

CLEPTY

Cleveland Hopkins Intl

Wed 2/3

6:00 am-5:12 pm

1 stop11h 12m

Panama City Tocumen Intl

Wed 2/17

8:55 am-6:23 pm

1 stop9h 28m

$607

ClevelandPanama City

CLE Cleveland Hopkins Intl - PTY Panama City Tocumen Intl

CLEPTY

Cleveland Hopkins Intl

Thu 12/10

8:25 am-8:02 pm

1 stop11h 37m

Panama City Tocumen Intl

Tue 12/15

10:00 am-10:08 pm

1 stop12h 08m

$607

ClevelandPanama City

CLE Cleveland Hopkins Intl - PTY Panama City Tocumen Intl

CLEPTY

Cleveland Hopkins Intl

Thu 2/4

5:59 pm-1:26 pm

2 stops19h 27m

Panama City Tocumen Intl

Tue 2/9

2:26 pm-9:32 am

2 stops19h 06m

$611

ClevelandPanama City

CLE Cleveland Hopkins Intl - PTY Panama City Tocumen Intl

CLEPTY

Cleveland Hopkins Intl

Thu 2/4

6:37 pm-1:26 pm

2 stops18h 49m

Panama City Tocumen Intl

Tue 2/9

2:26 pm-11:59 pm

1 stop9h 33m

$611

Quickest round-trip

ClevelandPanama City

CLE Cleveland Hopkins Intl - PTY Panama City Tocumen Intl

CLEPTY

Cleveland Hopkins Intl

Tue 3/23

6:00 am-1:00 pm

1 stop8h 00m

Panama City Tocumen Intl

Thu 3/25

2:25 pm-12:35 am

1 stop9h 10m

$654

ClevelandPanama City

CLE Cleveland Hopkins Intl - PTY Panama City Tocumen Intl

CLEPTY

Cleveland Hopkins Intl

Mon 3/22

6:00 am-1:00 pm

1 stop8h 00m

Panama City Tocumen Intl

Thu 3/25

2:25 pm-12:35 am

1 stop9h 10m

$654

ClevelandPanama City

CLE Cleveland Hopkins Intl - PTY Panama City Tocumen Intl

CLEPTY

Cleveland Hopkins Intl

Wed 11/25

7:53 am-8:02 pm

1 stop12h 09m

Panama City Tocumen Intl

Mon 11/30

4:41 pm-11:18 am

1 stop18h 37m

$656

ClevelandPanama City

CLE Cleveland Hopkins Intl - PTY Panama City Tocumen Intl

CLEPTY

Cleveland Hopkins Intl

Thu 12/10

5:45 am-8:02 pm

1 stop14h 17m

Panama City Tocumen Intl

Fri 12/18

10:00 am-9:54 pm

1 stop11h 54m

$691

ClevelandPanama City

CLE Cleveland Hopkins Intl - PTY Panama City Tocumen Intl

CLEPTY

Cleveland Hopkins Intl

Sun 12/13

12:57 pm-6:35 am

2 stops17h 38m

Panama City Tocumen Intl

Thu 12/17

9:48 pm-12:28 am

1 stop26h 40m

$754

ClevelandPanama City

CLE Cleveland Hopkins Intl - PTY Panama City Tocumen Intl

CLEPTY

Cleveland Hopkins Intl

Thu 11/5

7:00 am-5:15 pm

3 stops34h 15m

Panama City Tocumen Intl

Tue 11/10

4:10 pm-12:16 pm

3 stops20h 06m

$761

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 14 resultsSorted by cheapest first

How to get the cheapest flight ticket from Cleveland to Panama

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the cheapest month to fly to Panama?

The month of October is, on average, the cheapest month to fly to Panama from Cleveland, with most prices found around $570. If you don’t want to visit Panama in October, then you should wait until August to fly from Cleveland, when ticket prices are also cheap, with an average price of $600.

Can stopping save me money on Cleveland to Panama flights?

You could potentially save up to 59% on your flight if you consider stops on a Cleveland to Panama flight.

Cheap Cleveland to Panama flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Cleveland to Panama

Best Price Found	$348
Fastest flight time	8h 08m
Direct flights	None

The best one-way flight to Panama from Cleveland in the past 72 hours is $348. The best round-trip flight deal from Cleveland to Panama found on momondo in the last 72 hours is $607.

The fastest flight from Cleveland to Panama takes 8h 08m

There are no direct flights from Cleveland to Panama. There are no popular flight routes from Cleveland to Panama.

Search flight deals

Frequently asked questions about flying from Cleveland to Panama

When did momondo last update prices for flights from Cleveland Hopkins Intl Airport to Panama?
Prices for flights from Cleveland Hopkins Intl Airport to Panama are refreshed on a daily basis.
How many operators does momondo search for flights from Cleveland Hopkins Intl Airport to Panama?
As of October 2026, there are 4 operators available to choose from for flights from Cleveland Hopkins Intl Airport to Panama.
How old do you have to be to fly from Cleveland Hopkins Intl Airport to Panama?
The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Cleveland Hopkins Intl Airport to Panama.
What documentation or ID do you need to fly to Panama?
The travel and health documents you'll need for your trip to Panama may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Panama. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

Best airlines flying from Cleveland to Panama

Compare and see reviews for airlines that fly from Cleveland to Panama with momondo

Airline	Rating	Free Cancellation	Price
United Airlines	PriceFrom $489	Free Cancellation	Rating 7.4 10,276 reviews	Search United Airlines flights
American Airlines	PriceFrom $544	Free Cancellation	Rating 7.0 12,111 reviews	Search American Airlines flights
Delta	PriceFrom $570	Free Cancellation	Rating 7.8 8,621 reviews	Search Delta flights
Copa Airlines	PriceFrom $640	Free Cancellation	Rating 7.6 1,543 reviews	Search Copa Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Cleveland to Panama?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Cleveland to Panama. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Cleveland to Panama with flexible booking policies on momondo?

All flight searches from Cleveland to Panama on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Cleveland to Panama?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Cleveland to Panama.

I’m not ready to book a flight from Cleveland to Panama right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Cleveland to Panama flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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Flights to Panama Cityfrom $416

Flights to Bocas del Torofrom $1,035

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Cheap flights from Cleveland to Panama from $348

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Cleveland to Panama departing on 11/1. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.

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American Airlines flights from Cleveland to Panama

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How to get the cheapest flight ticket from Cleveland to Panama

What is the cheapest month to fly to Panama?

Can stopping save me money on Cleveland to Panama flights?

What is the cheapest airline that flies from Cleveland Hopkins Intl to Panama?

What airlines fly to Panama?

Cheap Cleveland to Panama flight deals and tips

Best Price Found

Fastest flight time

Direct flights

Frequently asked questions about flying from Cleveland to Panama

Best airlines flying from Cleveland to Panama

Compare and see reviews for airlines that fly from Cleveland to Panama with momondo

Why use momondo?

An easier way to manage your Panama trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

Find better results for your trip to Panama

Popular cities in Panama

Popular flights according to clicks in the last 7 days on momondo

Cleveland flight routes

According to popular flight searches on momondo this year

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According to popular flight searches on momondo this year

Fly your favorite airline to Panama

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Cabin classes currently available on flights to Panama

List of cabin classes available on flights landing in Panama. Availability may vary depending on flight origin and airline.

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According to popular flight searches on momondo this year