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Cheap flights from Cleveland to Panama from $232

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Cleveland to Panama departing on 9/26. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Cheap round-trip flights

Delta Logo
6:00 am - 12:56 pmCLE-PTY
7h 56m1 stop
Delta Logo
2:21 pm - 12:36 amPTY-CLE
9h 15m1 stop
$489Delta
Find Deal
Tue, Oct 14 - Mon, Oct 20
American Airlines Logo
5:24 am - 2:31 pmCLE-PTY
10h 07m2 stops
American Airlines Logo
3:31 pm - 11:48 amPTY-CLE
19h 17m2 stops
$494American Airlines
Find Deal
Fri, Sep 26 - Fri, Oct 3
Delta Logo
7:07 am - 12:55 pmCLE-PTY
6h 48m1 stop
Delta Logo
2:10 pm - 12:39 amPTY-CLE
9h 29m1 stop
$509Delta
Find Deal
Sat, Sep 27 - Tue, Sep 30
American Airlines Logo
6:00 am - 2:31 pmCLE-PTY
9h 31m2 stops
American Airlines Logo
3:31 pm - 12:28 pmPTY-CLE
19h 57m2 stops
$514American Airlines
Find Deal
Fri, Sep 12 - Fri, Sep 19
United Airlines Logo
3:17 pm - 6:37 pmCLE-PTY
28h 20m1 stop
United Airlines Logo
3:30 pm - 11:08 amPTY-CLE
18h 38m1 stop
$520United Airlines
Find Deal
Thu, Sep 25 - Mon, Sep 29
American Airlines Logo
6:00 am - 2:31 pmCLE-PTY
9h 31m1 stop
American Airlines Logo
3:31 pm - 1:38 pmPTY-CLE
21h 07m2 stops
$523American Airlines
Find Deal
Thu, Sep 25 - Mon, Sep 29
American Airlines Logo
5:30 am - 2:00 pmCLE-PTY
9h 30m2 stops
American Airlines Logo
3:15 pm - 12:14 amPTY-CLE
7h 59m1 stop
$525American Airlines
Find Deal
Wed, Oct 15 - Mon, Oct 20
United Airlines Logo
6:20 am - 2:14 pmCLE-PTY
8h 54m1 stop
United Airlines Logo
10:00 am - 10:12 pmPTY-CLE
11h 12m1 stop
$549United Airlines
Find Deal
Fri, Sep 12 - Fri, Sep 19
Avianca Logo
8:40 am - 8:55 amCLE-PTY
25h 15m2 stops
Avianca Logo
3:20 am - 7:02 pmPTY-CLE
14h 42m2 stops
$1,126Avianca
Find Deal
Fri, Sep 26 - Thu, Oct 2
Avianca Logo
9:00 am - 12:20 amCLE-PTY
15h 20m2 stops
Avianca Logo
3:19 am - 6:20 pmPTY-CLE
15h 01m2 stops
$1,180Avianca
Find Deal
Wed, Jan 14 - Sun, Jan 18

American Airlines flights from Cleveland to Panama

Our best American Airlines deals on Cleveland to Panama flight tickets
American Airlines
Sep 26
CLE5:24 amCleveland Hopkins Intl
10h 07m
2 stops
PTY2:31 pmPanama City Tocumen Intl
Oct 3
PTY3:31 pmPanama City Tocumen Intl
19h 17m
2 stops
CLE11:48 amCleveland Hopkins Intl
$494
Find similar
American Airlines
Sep 12
CLE6:00 amCleveland Hopkins Intl
9h 31m
2 stops
PTY2:31 pmPanama City Tocumen Intl
Sep 19
PTY3:31 pmPanama City Tocumen Intl
19h 57m
2 stops
CLE12:28 pmCleveland Hopkins Intl
$514
Find similar
American Airlines
Sep 25
CLE6:00 amCleveland Hopkins Intl
9h 31m
1 stop
PTY2:31 pmPanama City Tocumen Intl
Sep 29
PTY3:31 pmPanama City Tocumen Intl
21h 07m
2 stops
CLE1:38 pmCleveland Hopkins Intl
$523
Find similar

Delta flights from Cleveland to Panama

Our best Delta deals on Cleveland to Panama flight tickets
Delta
Oct 14
CLE6:00 amCleveland Hopkins Intl
7h 56m
1 stop
PTY12:56 pmPanama City Tocumen Intl
Oct 20
PTY2:21 pmPanama City Tocumen Intl
9h 15m
1 stop
CLE12:36 amCleveland Hopkins Intl
$489
Find similar
Delta
Sep 27
CLE7:07 amCleveland Hopkins Intl
6h 48m
1 stop
PTY12:55 pmPanama City Tocumen Intl
Sep 30
PTY2:10 pmPanama City Tocumen Intl
9h 29m
1 stop
CLE12:39 amCleveland Hopkins Intl
$509
Find similar
Delta
Nov 1
CLE7:05 amCleveland Hopkins Intl
6h 51m
1 stop
PTY12:56 pmPanama City Tocumen Intl
Nov 8
PTY3:21 pmPanama City Tocumen Intl
9h 15m
1 stop
CLE12:36 amCleveland Hopkins Intl
$529
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Cleveland to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated July 31, 2025.
Use the filters below to find and compare flights from Cleveland to Panama that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

ClevelandPanama City

CLE - PTY

CLEPTY

Cleveland Hopkins Intl

Tue 10/14

6:00 am-12:56 pm

1 stop7h 56m

Panama City Tocumen Intl

Mon 10/20

2:21 pm-12:36 am

1 stop9h 15m

$489

ClevelandPanama City

CLE - PTY

CLEPTY

Cleveland Hopkins Intl

Fri 9/26

5:24 am-2:31 pm

2 stops10h 07m

Panama City Tocumen Intl

Fri 10/3

3:31 pm-11:48 am

2 stops19h 17m

$494

ClevelandPanama City

CLE - PTY

CLEPTY

Cleveland Hopkins Intl

Sat 9/27

7:07 am-12:55 pm

1 stop6h 48m

Panama City Tocumen Intl

Tue 9/30

2:10 pm-12:39 am

1 stop9h 29m

$509

ClevelandPanama City

CLE - PTY

CLEPTY

Cleveland Hopkins Intl

Fri 9/12

6:00 am-2:31 pm

2 stops9h 31m

Panama City Tocumen Intl

Fri 9/19

3:31 pm-12:28 pm

2 stops19h 57m

$514

ClevelandPanama City

CLE - PTY

CLEPTY

Cleveland Hopkins Intl

Thu 9/25

3:17 pm-6:37 pm

1 stop28h 20m

Panama City Tocumen Intl

Mon 9/29

3:30 pm-11:08 am

1 stop18h 38m

$520

ClevelandPanama City

CLE - PTY

CLEPTY

Cleveland Hopkins Intl

Thu 9/25

6:00 am-2:31 pm

1 stop9h 31m

Panama City Tocumen Intl

Mon 9/29

3:31 pm-1:38 pm

2 stops21h 07m

$523

ClevelandPanama City

CLE - PTY

CLEPTY

Cleveland Hopkins Intl

Wed 10/15

5:30 am-2:00 pm

2 stops9h 30m

Panama City Tocumen Intl

Mon 10/20

3:15 pm-12:14 am

1 stop7h 59m

$525

ClevelandPanama City

CLE - PTY

CLEPTY

Cleveland Hopkins Intl

Fri 9/12

6:20 am-2:14 pm

1 stop8h 54m

Panama City Tocumen Intl

Fri 9/19

10:00 am-10:12 pm

1 stop11h 12m

$549

ClevelandPanama City

CLE - PTY

CLEPTY

Cleveland Hopkins Intl

Fri 9/26

8:40 am-8:55 am

2 stops25h 15m

Panama City Tocumen Intl

Thu 10/2

3:20 am-7:02 pm

2 stops14h 42m

$1,126

ClevelandPanama City

CLE - PTY

CLEPTY

Cleveland Hopkins Intl

Wed 1/14

9:00 am-12:20 am

2 stops15h 20m

Panama City Tocumen Intl

Sun 1/18

3:19 am-6:20 pm

2 stops15h 01m

$1,180

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 14 resultsSorted by cheapest first
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See travel insights to Panama from

How to get the cheapest flight ticket from Cleveland to Panama

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Panama?

The month of November is, on average, the cheapest month to fly to Panama from Cleveland, with most prices found around $469. If you don’t want to visit Panama in November, then you should wait until September to fly from Cleveland, when ticket prices are also cheap, with an average price of $489.

What is the cheapest day to depart on your flight to Panama?

According to our data, Friday is the cheapest day to fly to Panama from Cleveland. The lowest ticket price found for a Friday departure recently was $513. Keep in mind that prices can always vary depending on your route and whether or not you are flying domestic or international. When flying out on a Sunday, the most expensive travel day of the week, you can expect to see flight prices from Cleveland to Panama for around $744.

What is the cheapest time of day to depart on your flight to Panama?

In the morning is the cheapest time of day to fly from Cleveland to Panama when you can find flight prices for as low as $598. Flying to Panama in the morning is an ideal time because this is during off-peak travel hours. In the afternoon is when there is more demand to fly to Panama, so prices are often more expensive at around $746 per ticket.

Cheap Cleveland to Panama flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Cleveland to Panama

Best Price Found

$232

Fastest flight time

6h 48m

Direct flights

None

Airports in Panama

1 airport
The best one-way flight to Panama from Cleveland in the past 72 hours is $232. The best round-trip flight deal from Cleveland to Panama found on momondo in the last 72 hours is $489.
The fastest flight from Cleveland to Panama takes 6h 48m
There are no direct flights from Cleveland to Panama. Popular non-direct route for this connection is Cleveland Hopkins Intl Airport - Panama City Tocumen Intl Airport.
There is 1 airport near Panama: Panama City Tocumen Intl (PTY)
Search flight deals

  • When did momondo last update prices for flights from Cleveland Hopkins Intl Airport to Panama?

    Prices for flights from Cleveland Hopkins Intl Airport to Panama are refreshed on a daily basis.

  • How many operators does momondo search for flights from Cleveland Hopkins Intl Airport to Panama?

  • How old do you have to be to fly from Cleveland Hopkins Intl Airport to Panama?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Cleveland Hopkins Intl Airport to Panama.

  • What documentation or ID do you need to fly to Panama?

    The travel and health documents you'll need for your trip to Panama may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Panama. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

Best airlines flying from Cleveland to Panama

Compare and see reviews for airlines that fly from Cleveland to Panama with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $389Free CancellationRating
8.0
7,981 reviews
Search Delta flights
American AirlinesPriceFrom $390Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights
United AirlinesPriceFrom $469Free CancellationRating
7.4
8,900 reviews
Search United Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Cleveland to Panama?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Cleveland to Panama. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Cleveland to Panama with flexible booking policies on momondo?

All flight searches from Cleveland to Panama on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Cleveland to Panama?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Cleveland to Panama.

I’m not ready to book a flight from Cleveland to Panama right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Cleveland to Panama flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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