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Cheap flights from Cleveland to Panama from $217

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Cleveland to Panama departing on 12/4. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Cleveland to Panama

Cheap round-trip flights

Enter your travel dates to find the best prices.
United Airlines Logo
6:00 am - 2:45 pmCLE-PTY
8h 45m1 stop
United Airlines Logo
11:35 am - 9:58 pmPTY-CLE
10h 23m1 stop
$490United Airlines
Find Deal
Thu, Jan 29 - Mon, Feb 2
American Airlines Logo
6:00 am - 3:38 pmCLE-PTY
9h 38m2 stops
American Airlines Logo
2:52 pm - 9:52 amPTY-CLE
19h 00m2 stops
$494American Airlines
Find Deal
Thu, Jan 22 - Tue, Feb 24
United Airlines Logo
6:00 pm - 2:45 pmCLE-PTY
20h 45m1 stop
United Airlines Logo
4:41 pm - 11:08 amPTY-CLE
18h 27m1 stop
$500United Airlines
Find Deal
Wed, Jan 14 - Mon, Jan 19
United Airlines Logo
6:00 am - 7:38 pmCLE-PTY
13h 38m1 stop
United Airlines Logo
4:41 pm - 11:08 amPTY-CLE
18h 27m1 stop
$510United Airlines
Find Deal
Mon, Feb 2 - Sat, Feb 7
American Airlines Logo
7:47 pm - 3:38 pmCLE-PTY
19h 51m2 stops
American Airlines Logo
2:27 pm - 10:00 amPTY-CLE
19h 33m2 stops
$514American Airlines
Find Deal
Thu, Jan 29 - Mon, Feb 2
American Airlines Logo
6:00 am - 3:38 pmCLE-PTY
9h 38m2 stops
American Airlines Logo
2:27 pm - 10:17 amPTY-CLE
19h 50m2 stops
$519American Airlines
Find Deal
Fri, Jan 9 - Sun, Jan 25
Delta Logo
7:15 am - 2:21 pmCLE-PTY
7h 06m1 stop
Delta Logo
8:05 am - 9:13 pmPTY-CLE
13h 08m1 stop
$550Delta
Find Deal
Wed, Dec 3 - Sat, Dec 6
Delta Logo
7:15 am - 7:59 pmCLE-PTY
12h 44m1 stop
Delta Logo
8:05 am - 6:40 pmPTY-CLE
10h 35m1 stop
$570Delta
Find Deal
Fri, Dec 5 - Sun, Dec 7
Copa Airlines Logo
10:42 am - 8:35 pmCLE-PTY
9h 53m1 stop
Copa Airlines Logo
10:29 pm - 9:51 amPTY-CLE
11h 22m1 stop
$702Copa Airlines
Find Deal
Sun, Dec 21 - Mon, Jan 5
Copa Airlines Logo
7:49 pm - 6:13 amCLE-PTY
10h 24m1 stop
Copa Airlines Logo
10:29 pm - 9:51 amPTY-CLE
11h 22m1 stop
$783Copa Airlines
Find Deal
Sat, Dec 20 - Mon, Jan 5

United Airlines flights from Cleveland to Panama

Our best United Airlines deals on Cleveland to Panama flight tickets
United Airlines
Jan 29
CLE6:00 amCleveland Hopkins Intl
8h 45m
1 stop
PTY2:45 pmPanama City Tocumen Intl
Feb 2
PTY11:35 amPanama City Tocumen Intl
10h 23m
1 stop
CLE9:58 pmCleveland Hopkins Intl
$490
Find similar
United Airlines
Jan 14
CLE6:00 pmCleveland Hopkins Intl
20h 45m
1 stop
PTY2:45 pmPanama City Tocumen Intl
Jan 19
PTY4:41 pmPanama City Tocumen Intl
18h 27m
1 stop
CLE11:08 amCleveland Hopkins Intl
$500
Find similar
United Airlines
Feb 2
CLE6:00 amCleveland Hopkins Intl
13h 38m
1 stop
PTY7:38 pmPanama City Tocumen Intl
Feb 7
PTY4:41 pmPanama City Tocumen Intl
18h 27m
1 stop
CLE11:08 amCleveland Hopkins Intl
$510
Find similar

Copa Airlines flights from Cleveland to Panama

Our best Copa Airlines deals on Cleveland to Panama flight tickets
Copa Airlines
Dec 21
CLE10:42 amCleveland Hopkins Intl
9h 53m
1 stop
PTY8:35 pmPanama City Tocumen Intl
Jan 5
PTY10:29 pmPanama City Tocumen Intl
11h 22m
1 stop
CLE9:51 amCleveland Hopkins Intl
$702
Find similar
Copa Airlines
Dec 20
CLE7:49 pmCleveland Hopkins Intl
10h 24m
1 stop
PTY6:13 amPanama City Tocumen Intl
Jan 5
PTY10:29 pmPanama City Tocumen Intl
11h 22m
1 stop
CLE9:51 amCleveland Hopkins Intl
$783
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Cleveland to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated November 4, 2025.
Use the filters below to find and compare flights from Cleveland to Panama that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

ClevelandPanama City

CLE - PTY

CLEPTY

Cleveland Hopkins Intl

Thu 1/29

6:00 am-2:45 pm

1 stop8h 45m

Panama City Tocumen Intl

Mon 2/2

11:35 am-9:58 pm

1 stop10h 23m

$490

ClevelandPanama City

CLE - PTY

CLEPTY

Cleveland Hopkins Intl

Thu 1/22

6:00 am-3:38 pm

2 stops9h 38m

Panama City Tocumen Intl

Tue 2/24

2:52 pm-9:52 am

2 stops19h 00m

$494

ClevelandPanama City

CLE - PTY

CLEPTY

Cleveland Hopkins Intl

Wed 1/14

6:00 pm-2:45 pm

1 stop20h 45m

Panama City Tocumen Intl

Mon 1/19

4:41 pm-11:08 am

1 stop18h 27m

$500

ClevelandPanama City

CLE - PTY

CLEPTY

Cleveland Hopkins Intl

Mon 2/2

6:00 am-7:38 pm

1 stop13h 38m

Panama City Tocumen Intl

Sat 2/7

4:41 pm-11:08 am

1 stop18h 27m

$510

ClevelandPanama City

CLE - PTY

CLEPTY

Cleveland Hopkins Intl

Thu 1/29

7:47 pm-3:38 pm

2 stops19h 51m

Panama City Tocumen Intl

Mon 2/2

2:27 pm-10:00 am

2 stops19h 33m

$514

ClevelandPanama City

CLE - PTY

CLEPTY

Cleveland Hopkins Intl

Fri 1/9

6:00 am-3:38 pm

2 stops9h 38m

Panama City Tocumen Intl

Sun 1/25

2:27 pm-10:17 am

2 stops19h 50m

$519

ClevelandPanama City

CLE - PTY

CLEPTY

Cleveland Hopkins Intl

Wed 12/3

7:15 am-2:21 pm

1 stop7h 06m

Panama City Tocumen Intl

Sat 12/6

8:05 am-9:13 pm

1 stop13h 08m

$550

ClevelandPanama City

CLE - PTY

CLEPTY

Cleveland Hopkins Intl

Fri 12/5

7:15 am-7:59 pm

1 stop12h 44m

Panama City Tocumen Intl

Sun 12/7

8:05 am-6:40 pm

1 stop10h 35m

$570

ClevelandPanama City

CLE - PTY

CLEPTY

Cleveland Hopkins Intl

Sun 12/21

10:42 am-8:35 pm

1 stop9h 53m

Panama City Tocumen Intl

Mon 1/5

10:29 pm-9:51 am

1 stop11h 22m

$702

ClevelandPanama City

CLE - PTY

CLEPTY

Cleveland Hopkins Intl

Sat 12/20

7:49 pm-6:13 am

1 stop10h 24m

Panama City Tocumen Intl

Mon 1/5

10:29 pm-9:51 am

1 stop11h 22m

$783

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Panama from

How to get the cheapest flight ticket from Cleveland to Panama

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Panama?

The month of November is, on average, the cheapest month to fly to Panama from Cleveland, with most prices found around $489. If you don’t want to visit Panama in November, then you should wait until September to fly from Cleveland, when ticket prices are also cheap, with an average price of $506.

What is the cheapest day to depart on your flight to Panama?

According to our data, Friday is the cheapest day to fly to Panama from Cleveland. The lowest ticket price found for a Friday departure recently was $513. Keep in mind that prices can always vary depending on your route and whether or not you are flying domestic or international. When flying out on a Sunday, the most expensive travel day of the week, you can expect to see flight prices from Cleveland to Panama for around $744.

What is the cheapest time of day to depart on your flight to Panama?

In the morning is the cheapest time of day to fly from Cleveland to Panama when you can find flight prices for as low as $598. Flying to Panama in the morning is an ideal time because this is during off-peak travel hours. In the afternoon is when there is more demand to fly to Panama, so prices are often more expensive at around $746 per ticket.

Cheap Cleveland to Panama flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Cleveland to Panama

Direct flights

None
There are no direct flights from Cleveland to Panama. There are no popular flight routes from Cleveland to Panama.
Search flight deals

  • When did momondo last update prices for flights from Cleveland Hopkins Intl Airport to Panama?

    Prices for flights from Cleveland Hopkins Intl Airport to Panama are refreshed on a daily basis.

  • How many operators does momondo search for flights from Cleveland Hopkins Intl Airport to Panama?

  • How old do you have to be to fly from Cleveland Hopkins Intl Airport to Panama?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Cleveland Hopkins Intl Airport to Panama.

  • What documentation or ID do you need to fly to Panama?

    The travel and health documents you'll need for your trip to Panama may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Panama. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

Best airlines flying from Cleveland to Panama

Compare and see reviews for airlines that fly from Cleveland to Panama with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $389Free CancellationRating
7.9
8,003 reviews
Search Delta flights
American AirlinesPriceFrom $469Free CancellationRating
7.2
11,040 reviews
Search American Airlines flights
United AirlinesPriceFrom $469Free CancellationRating
7.4
9,002 reviews
Search United Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Cleveland to Panama?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Cleveland to Panama. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Cleveland to Panama with flexible booking policies on momondo?

All flight searches from Cleveland to Panama on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Cleveland to Panama?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Cleveland to Panama.

I’m not ready to book a flight from Cleveland to Panama right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Cleveland to Panama flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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