What airlines fly to South America?

American Airlines, Delta and LATAM Airlines are the top three most popular airlines that fly to South America from Charleston according to our data. American Airlines is the first choice among our users, with 53% of people opting to fly with this airline when traveling to South America. Keep in mind that there are 3 different airlines that fly to South America on a routine basis, so you have a few additional options to choose from.

What is the cheapest airline that flies from Charleston to South America?

American Airlines, JetBlue, and United Airlines are the most popular carriers operating from Charleston to South America

When did momondo last update prices for flights from Charleston Airport to South America?

Prices for flights from Charleston Airport to South America are refreshed on a daily basis.

How many operators does momondo search for flights from Charleston Airport to South America?

The number of operators available for flights from Charleston Airport to South America is 3 as of June 2026.

How old do you have to be to fly from Charleston Airport to South America?

The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Charleston Airport to South America.

What documentation or ID do you need to fly to South America?

The necessary travel and health documents for your South America trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

$220 Cheap Flights from Charleston to South America in 2026

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Charleston to South America

Round-trip

One-way

Last minute

Cheap round-trip flights

Enter your travel dates to find the best prices.

11:04 am - 2:17 pm

CHS

CTG

28h 13m

1 stop

3:17 pm - 12:29 pm

CTG

CHS

20h 12m

2 stops

$472American Airlines

Fri, Jul 24 - Tue, Jul 28

8:13 pm - 12:35 pm

CHS

CTG

17h 22m

1 stop

3:17 pm - 6:51 pm

CTG

CHS

26h 34m

1 stop

$477American Airlines

Fri, Jul 24 - Tue, Jul 28

6:40 pm - 11:35 am

CHS

CTG

17h 55m

1 stop

12:35 pm - 5:50 pm

CTG

CHS

28h 15m

1 stop

$498JetBlue

Sat, Jul 25 - Tue, Jul 28

11:05 am - 6:35 am

CHS

UIO

20h 30m

1 stop

5:20 pm - 9:59 am

UIO

CHS

15h 39m

1 stop

$502Multiple Airlines

Tue, Oct 13 - Fri, Oct 30

5:27 pm - 11:35 am

CHS

CTG

19h 08m

1 stop

12:35 pm - 4:31 pm

CTG

CHS

26h 56m

1 stop

$512JetBlue

Sat, Aug 22 - Sat, Aug 29

2:53 pm - 2:45 am

CHS

BOG

12h 52m

1 stop

4:05 pm - 8:38 am

BOG

CHS

15h 33m

1 stop

$524Multiple Airlines

Thu, Aug 6 - Mon, Aug 10

11:25 am - 7:15 pm

CHS

BOG

8h 50m

1 stop

2:55 pm - 11:59 pm

BOG

CHS

8h 04m

1 stop

$585LATAM Airlines

Mon, Aug 3 - Mon, Aug 10

11:25 am - 7:15 pm

CHS

BOG

8h 50m

1 stop

11:00 am - 11:59 pm

BOG

CHS

11h 59m

2 stops

$590LATAM Airlines

Mon, Aug 3 - Mon, Aug 10

5:10 am - 7:15 pm

CHS

BOG

15h 05m

1 stop

2:55 pm - 8:58 am

BOG

CHS

17h 03m

1 stop

$605Delta

Fri, Jul 31 - Mon, Aug 10

5:10 am - 1:40 pm

CHS

BOG

9h 30m

1 stop

2:55 pm - 11:59 pm

BOG

CHS

8h 04m

1 stop

$609Delta

Wed, Aug 5 - Mon, Aug 10

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LATAM Airlines flights from Charleston to South America

Our best LATAM Airlines deals on Charleston to South America flight tickets

LATAM Airlines

Nov 5

CHS6:30 amCharleston

7h 45m

1 stop

CTG2:15 pmCartagena Rafael Nunez

Nov 9

CTG3:25 pmCartagena Rafael Nunez

8h 31m

1 stop

CHS11:56 pmCharleston

$579

LATAM Airlines

Aug 3

CHS11:25 amCharleston

8h 50m

1 stop

BOG7:15 pmBogotá El Dorado

Aug 10

BOG2:55 pmBogotá El Dorado

8h 04m

1 stop

CHS11:59 pmCharleston

$585

LATAM Airlines

Aug 3

CHS11:25 amCharleston

8h 50m

1 stop

BOG7:15 pmBogotá El Dorado

Aug 10

BOG11:00 amBogotá El Dorado

11h 59m

2 stops

CHS11:59 pmCharleston

$590

American Airlines flights from Charleston to South America

Our best American Airlines deals on Charleston to South America flight tickets

American Airlines

Jul 24

CHS11:04 amCharleston

28h 13m

1 stop

CTG2:17 pmCartagena Rafael Nunez

Jul 28

CTG3:17 pmCartagena Rafael Nunez

20h 12m

2 stops

CHS12:29 pmCharleston

$472

American Airlines

Jul 24

CHS8:13 pmCharleston

17h 22m

1 stop

CTG12:35 pmCartagena Rafael Nunez

Jul 28

CTG3:17 pmCartagena Rafael Nunez

26h 34m

1 stop

CHS6:51 pmCharleston

$477

American Airlines

Jul 3

CHS8:13 pmCharleston

17h 22m

1 stop

CTG12:35 pmCartagena Rafael Nunez

Jul 9

CTG3:17 pmCartagena Rafael Nunez

27h 16m

1 stop

CHS7:33 pmCharleston

$521

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

CharlestonCartagena

CHS - CTG

CHSCTG

Charleston

Fri 7/24

11:04 am-2:17 pm

1 stop28h 13m

Cartagena Rafael Nunez

Tue 7/28

3:17 pm-12:29 pm

2 stops20h 12m

$472

CharlestonCartagena

CHS - CTG

CHSCTG

Charleston

Fri 7/24

8:13 pm-12:35 pm

1 stop17h 22m

Cartagena Rafael Nunez

Tue 7/28

3:17 pm-6:51 pm

1 stop26h 34m

$477

CharlestonCartagena

CHS - CTG

CHSCTG

Charleston

Sat 7/25

6:40 pm-11:35 am

1 stop17h 55m

Cartagena Rafael Nunez

Tue 7/28

12:35 pm-5:50 pm

1 stop28h 15m

$498

CharlestonQuito

CHS - UIO

CHSUIO

Charleston

Tue 10/13

11:05 am-6:35 am

1 stop20h 30m

Quito Mariscal Sucr

Fri 10/30

5:20 pm-9:59 am

1 stop15h 39m

$502

CharlestonCartagena

CHS - CTG

CHSCTG

Charleston

Sat 8/22

5:27 pm-11:35 am

1 stop19h 08m

Cartagena Rafael Nunez

Sat 8/29

12:35 pm-4:31 pm

1 stop26h 56m

$512

CharlestonBogotá

CHS - BOG

CHSBOG

Charleston

Thu 8/6

2:53 pm-2:45 am

1 stop12h 52m

Bogotá El Dorado

Mon 8/10

4:05 pm-8:38 am

1 stop15h 33m

$524

Quickest round-trip

CharlestonBogotá

CHS - BOG

CHSBOG

Charleston

Mon 8/3

11:25 am-7:15 pm

1 stop8h 50m

Bogotá El Dorado

Mon 8/10

2:55 pm-11:59 pm

1 stop8h 04m

$585

CharlestonBogotá

CHS - BOG

CHSBOG

Charleston

Mon 8/3

11:25 am-7:15 pm

1 stop8h 50m

Bogotá El Dorado

Mon 8/10

11:00 am-11:59 pm

2 stops11h 59m

$590

CharlestonBogotá

CHS - BOG

CHSBOG

Charleston

Fri 7/31

5:10 am-7:15 pm

1 stop15h 05m

Bogotá El Dorado

Mon 8/10

2:55 pm-8:58 am

1 stop17h 03m

$605

CharlestonBogotá

CHS - BOG

CHSBOG

Charleston

Wed 8/5

5:10 am-1:40 pm

1 stop9h 30m

Bogotá El Dorado

Mon 8/10

2:55 pm-11:59 pm

1 stop8h 04m

$609

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Charleston to South America

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the cheapest month to fly to South America?

In general, September is the cheapest month to fly from Charleston to South America. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $156. If you aren’t able to travel during the month of September, then book flights to South America from Charleston during April instead. Flights to South America in April, while not as cheap as those in September, still average around $275.

Can stopping save me money on Charleston to South America flights?

You could potentially save up to 9% on your flight if you consider stops on a Charleston to South America flight.

Cheap Charleston to South America flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Charleston to South America

Fastest flight time	7h 35m
Direct flights	None

The fastest flight from Charleston to South America takes 7h 35m

There are no direct flights from Charleston to South America. There are no popular flight routes from Charleston to South America.

Search flight deals

Frequently asked questions about flying from Charleston to South America

When did momondo last update prices for flights from Charleston Airport to South America?
Prices for flights from Charleston Airport to South America are refreshed on a daily basis.
How many operators does momondo search for flights from Charleston Airport to South America?
The number of operators available for flights from Charleston Airport to South America is 3 as of June 2026.
How old do you have to be to fly from Charleston Airport to South America?
The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Charleston Airport to South America.
What documentation or ID do you need to fly to South America?
The necessary travel and health documents for your South America trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Best airlines flying from Charleston to South America

Compare and see reviews for airlines that fly from Charleston to South America with momondo

Airline	Rating	Free Cancellation	Price
Delta	PriceFrom $301	Free Cancellation	Rating 7.9 8,396 reviews	Search Delta flights
American Airlines	PriceFrom $493	Free Cancellation	Rating 7.1 11,640 reviews	Search American Airlines flights
LATAM Airlines	PriceFrom $542	Free Cancellation	Rating 7.4 1,926 reviews	Search LATAM Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Charleston to South America?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to South America from Charleston.

Can I find flights from Charleston to South America with flexible booking policies on momondo?

Flights from Charleston to South America with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Charleston to South America?

Once all potential Charleston to South America flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Charleston to South America right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to South America from Charleston. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.