Cheap flights from California to Panama from $197

The month of September is, on average, the cheapest month to fly to Panama from California, with most prices found around $519. If you don’t want to visit Panama in September, then you should wait until August to fly from California, when ticket prices are also cheap, with an average price of $521.

According to our data, Wednesday is the cheapest day to fly to Panama from California. The lowest ticket price found for a Wednesday departure recently was $606. Keep in mind that prices can always vary depending on your route and whether or not you are flying domestic or international. When flying out on a Saturday, the most expensive travel day of the week, you can expect to see flight prices from California to Panama for around $662.

In the morning is the cheapest time of day to fly from California to Panama when you can find flight prices for as low as $611. Flying to Panama in the morning is an ideal time because this is during off-peak travel hours. In the evening is when there is more demand to fly to Panama, so prices are often more expensive at around $629 per ticket.

Fly from San Diego to Panama City Tocumen Intl for the best California - Panama flight prices

You are more likely to see cheaper flights to Panama from California when booking weeks ahead of your departure date. In general, you can expect to find flights to Panama for around $618 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Panama from California for as low as $564 on momondo.

There are 3 cabin classes available to choose from on California to Panama flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Delta, United Airlines, and American Airlines are the most popular carriers operating from California to Panama

Copa Airlines, United Airlines and Avianca are the top three most popular airlines that fly to Panama from California according to our data. Copa Airlines is the first choice among our users, with 66% of people opting to fly with this airline when traveling to Panama. Keep in mind that there are 5 different airlines that fly to Panama on a routine basis, so you have a few additional options to choose from.

15 flights are operational daily from California to Panama as of March 2026. The most popular departure time for this route is 2:00AM, with 59% of flights per day taking off in the morning.

As of March 2026, there are 105 flights per week flying from California to Panama. The most common day of the week flights depart is Wed, with 16% of flights taking off on this day.