What airlines fly to Spain?

American Airlines, British Airways and United Airlines are the top three most popular airlines that fly to Spain from South Carolina according to our data. American Airlines is the first choice among our users, with 47% of people opting to fly with this airline when traveling to Spain. Keep in mind that there are 7 different airlines that fly to Spain on a routine basis, so you have a few additional options to choose from.

How long is the flight from South Carolina to Spain?

Flight times from South Carolina to Spain vary, but if you’re flying out of Greenville and flying into Madrid (one of the most popular routes), then the duration is 10h 42m on average. Another popular route from South Carolina to Spain is flying from Charleston to Madrid, which will take roughly 11h 05m. Keep in mind that layovers or delays could extend your travel time.

What is the cheapest airline that flies from South Carolina to Spain?

British Airways, Lufthansa, and Air Canada are the most popular carriers operating from South Carolina to Spain

When did momondo last update prices for flights from South Carolina to Spain?

Prices for flights from South Carolina to Spain refresh daily.

How many operators does momondo search for flights from South Carolina to Spain?

There are 6 operators available for flights from South Carolina to Spain as of October 2026.

How old do you have to be to fly from South Carolina to Spain?

Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from South Carolina to Spain.

What documentation or ID do you need to fly to Spain?

The required travel and health documents for your Spain trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Spain. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

$341 Cheap Flights from South Carolina to Spain in 2026/27

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from South Carolina to Spain

Round-trip

One-way

Last minute

Cheap round-trip flights

Enter your travel dates to find the best prices.

10:52 am - 9:45 amMYR Myrtle Beach Intl-MAD Madrid Barajas

16h 53m1 stop Atlanta Hartsfield-Jackson

9:20 am - 6:01 pmMAD Madrid Barajas-MYR Myrtle Beach Intl

38h 41m2 stops New York John F Kennedy Intl Atlanta Hartsfield-Jackson

$677Virgin Atlantic

Tue, Nov 10 - Tue, Nov 17

10:52 am - 9:45 amMYR Myrtle Beach Intl-MAD Madrid Barajas

16h 53m1 stop Atlanta Hartsfield-Jackson

9:20 am - 10:54 pmMAD Madrid Barajas-MYR Myrtle Beach Intl

19h 34m2 stops New York John F Kennedy Intl Atlanta Hartsfield-Jackson

$677Virgin Atlantic

Wed, Nov 11 - Wed, Nov 18

5:34 pm - 11:05 pmGSP Greenville-BCN Barcelona-El Prat

23h 31m2 stops Chicago O'Hare Intl Munich Franz Josef Strauss

6:50 am - 11:40 pmBCN Barcelona-El Prat-GSP Greenville

22h 50m2 stops Frankfurt am Main Newark

$719Lufthansa

Wed, Dec 9 - Wed, Dec 16

3:03 pm - 9:00 amGSP Greenville-BCN Barcelona-El Prat

11h 57m1 stop Washington, D.C. Dulles Intl

1:35 pm - 10:35 pmBCN Barcelona-El Prat-GSP Greenville

39h 00m2 stops Montreal Pierre Elliott Trudeau Intl Newark

$720United Airlines

Wed, Dec 9 - Wed, Dec 16

7:42 pm - 5:35 pmGSP Greenville-BCN Barcelona-El Prat

15h 53m2 stops Washington, D.C. Dulles Intl Munich Franz Josef Strauss

5:45 am - 11:34 pmBCN Barcelona-El Prat-GSP Greenville

23h 49m2 stops Frankfurt am Main Newark

$722Lufthansa

Tue, Jan 5 - Thu, Jan 14

10:58 am - 9:10 amGSP Greenville-BCN Barcelona-El Prat

16h 12m1 stop Philadelphia

12:00 pm - 8:46 pmBCN Barcelona-El Prat-GSP Greenville

14h 46m1 stop Philadelphia

$722British Airways

Wed, Feb 3 - Tue, Feb 9

3:03 pm - 7:45 amGSP Greenville-MAD Madrid Barajas

10h 42m1 stop Washington, D.C. Dulles Intl

1:25 pm - 1:26 pmMAD Madrid Barajas-GSP Greenville

30h 01m2 stops Montreal Pierre Elliott Trudeau Intl Chicago O'Hare Intl

$724United Airlines

Tue, Dec 8 - Tue, Dec 15

12:57 pm - 9:35 amMYR Myrtle Beach Intl-MAD Madrid Barajas

14h 38m1 stop Philadelphia

3:25 pm - 9:56 pmMAD Madrid Barajas-MYR Myrtle Beach Intl

12h 31m1 stop Philadelphia

$724British Airways

Wed, Apr 14 - Wed, Apr 28

12:12 pm - 9:45 amGSP Greenville-MAD Madrid Barajas

15h 33m1 stop Atlanta Hartsfield-Jackson

9:20 am - 7:56 pmMAD Madrid Barajas-GSP Greenville

16h 36m2 stops New York John F Kennedy Intl Atlanta Hartsfield-Jackson

$725KLM

Mon, Nov 23 - Tue, Dec 8

8:11 am - 7:20 amGSP Greenville-MAD Madrid Barajas

17h 09m2 stops Atlanta Hartsfield-Jackson New York John F Kennedy Intl

9:20 am - 7:56 pmMAD Madrid Barajas-GSP Greenville

16h 36m2 stops New York John F Kennedy Intl Atlanta Hartsfield-Jackson

$725KLM

Mon, Nov 23 - Tue, Dec 8

Cheap last minute flights

Enter your travel dates to find the best prices.

7:43 pm - 7:45 amGSP Greenville-MAD Madrid Barajas

30h 02m1 stop Washington, D.C. Dulles Intl

6:05 am - 9:30 amMAD Madrid Barajas-GSP Greenville

33h 25m2 stops Frankfurt am Main Chicago O'Hare Intl

$799United Airlines

Sun, Nov 1 - Tue, Nov 10

6:49 am - 7:45 amGSP Greenville-MAD Madrid Barajas

42h 56m2 stops Houston George Bush Intcntl Washington, D.C. Dulles Intl

6:05 am - 9:30 amMAD Madrid Barajas-GSP Greenville

33h 25m2 stops Frankfurt am Main Chicago O'Hare Intl

$810United Airlines

Sun, Nov 1 - Tue, Nov 10

2:18 pm - 8:40 amCHS Charleston-BCN Barcelona-El Prat

12h 22m1 stop Atlanta Hartsfield-Jackson

10:50 am - 5:59 pmBCN Barcelona-El Prat-CHS Charleston

13h 09m1 stop Atlanta Hartsfield-Jackson

$820Multiple Airlines

Mon, Nov 2 - Mon, Nov 9

2:18 pm - 8:40 amCHS Charleston-BCN Barcelona-El Prat

12h 22m1 stop Atlanta Hartsfield-Jackson

1:10 pm - 11:59 pmBCN Barcelona-El Prat-CHS Charleston

16h 49m2 stops Amsterdam Schiphol Atlanta Hartsfield-Jackson

$820Multiple Airlines

Mon, Nov 2 - Mon, Nov 9

12:57 pm - 9:00 amCHS Charleston-BCN Barcelona-El Prat

14h 03m2 stops New York John F Kennedy Intl Paris Charles de Gaulle

1:10 pm - 11:59 pmBCN Barcelona-El Prat-CHS Charleston

16h 49m2 stops Amsterdam Schiphol Atlanta Hartsfield-Jackson

$838Multiple Airlines

Mon, Nov 2 - Mon, Nov 9

7:43 pm - 7:45 amGSP Greenville-MAD Madrid Barajas

30h 02m1 stop Washington, D.C. Dulles Intl

11:15 am - 11:00 pmMAD Madrid Barajas-GSP Greenville

17h 45m1 stop Newark

$942United Airlines

Sun, Nov 1 - Tue, Nov 10

7:55 am - 8:55 amGSP Greenville-MAD Madrid Barajas

19h 00m1 stop Philadelphia

12:05 pm - 10:17 amMAD Madrid Barajas-GSP Greenville

52h 12m2 stops London Heathrow Philadelphia

$1,069British Airways

Sun, Nov 1 - Sat, Nov 7

7:55 am - 8:55 amGSP Greenville-MAD Madrid Barajas

19h 00m1 stop Philadelphia

1:15 pm - 7:51 pmMAD Madrid Barajas-GSP Greenville

12h 36m1 stop Philadelphia

$1,193British Airways

Sun, Nov 1 - Sat, Nov 7

7:55 am - 8:55 amGSP Greenville-MAD Madrid Barajas

19h 00m1 stop Philadelphia

1:15 pm - 7:51 pmMAD Madrid Barajas-GSP Greenville

12h 36m1 stop Philadelphia

$1,203British Airways

Sun, Nov 1 - Sat, Nov 7

11:39 am - 8:50 amGSP Greenville-MAD Madrid Barajas

15h 11m1 stop Chicago O'Hare Intl

12:40 pm - 9:59 pmMAD Madrid Barajas-GSP Greenville

15h 19m1 stop Chicago O'Hare Intl

$1,237American Airlines

Sun, Nov 1 - Sat, Nov 7

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British Airways flights from South Carolina to Spain

Our best British Airways deals on South Carolina to Spain flight tickets

British Airways

Apr 14

MYR12:57 pmMyrtle Beach Intl

14h 38m

1 stop

MAD9:35 amMadrid Barajas

Apr 28

MAD3:25 pmMadrid Barajas

12h 31m

1 stop

MYR9:56 pmMyrtle Beach Intl

$724

British Airways

Feb 24

CHS10:56 amCharleston

16h 14m

1 stop

BCN9:10 amBarcelona-El Prat

Mar 10

BCN12:00 pmBarcelona-El Prat

17h 21m

1 stop

CHS11:21 pmCharleston

$739

British Airways

Dec 30

GSP4:02 pmGreenville

20h 28m

2 stops

BCN6:30 pmBarcelona-El Prat

Jan 14

BCN6:35 amBarcelona-El Prat

20h 11m

2 stops

GSP8:46 pmGreenville

$741

United Airlines flights from South Carolina to Spain

Our best United Airlines deals on South Carolina to Spain flight tickets

United Airlines

Dec 9

GSP3:03 pmGreenville

11h 57m

1 stop

BCN9:00 amBarcelona-El Prat

Dec 16

BCN1:35 pmBarcelona-El Prat

39h 00m

2 stops

GSP10:35 pmGreenville

$720

United Airlines

Dec 1

CAE12:30 pmColumbia Metropolitan

15h 00m

1 stop

MAD9:30 amMadrid Barajas

Dec 8

MAD1:25 pmMadrid Barajas

33h 44m

2 stops

CAE5:09 pmColumbia Metropolitan

$724

United Airlines

Jan 6

GSP2:57 pmGreenville

20h 38m

2 stops

BCN5:35 pmBarcelona-El Prat

Jan 21

BCN1:35 pmBarcelona-El Prat

39h 59m

2 stops

GSP11:34 pmGreenville

$726

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Myrtle BeachMadrid

MYR Myrtle Beach Intl - MAD Madrid Barajas

MYRMAD

Myrtle Beach Intl

Tue 11/10

10:52 am-9:45 am

1 stop16h 53m

Madrid Barajas

Tue 11/17

9:20 am-6:01 pm

2 stops38h 41m

$677

Myrtle BeachMadrid

MYR Myrtle Beach Intl - MAD Madrid Barajas

MYRMAD

Myrtle Beach Intl

Wed 11/11

10:52 am-9:45 am

1 stop16h 53m

Madrid Barajas

Wed 11/18

9:20 am-10:54 pm

2 stops19h 34m

$677

GreenvilleBarcelona

GSP Greenville - BCN Barcelona-El Prat

GSPBCN

Greenville

Wed 12/9

5:34 pm-11:05 pm

2 stops23h 31m

Barcelona-El Prat

Wed 12/16

6:50 am-11:40 pm

2 stops22h 50m

$719

GreenvilleBarcelona

GSP Greenville - BCN Barcelona-El Prat

GSPBCN

Greenville

Wed 12/9

3:03 pm-9:00 am

1 stop11h 57m

Barcelona-El Prat

Wed 12/16

1:35 pm-10:35 pm

2 stops39h 00m

$720

GreenvilleBarcelona

GSP Greenville - BCN Barcelona-El Prat

GSPBCN

Greenville

Tue 1/5

7:42 pm-5:35 pm

2 stops15h 53m

Barcelona-El Prat

Thu 1/14

5:45 am-11:34 pm

2 stops23h 49m

$722

GreenvilleBarcelona

GSP Greenville - BCN Barcelona-El Prat

GSPBCN

Greenville

Wed 2/3

10:58 am-9:10 am

1 stop16h 12m

Barcelona-El Prat

Tue 2/9

12:00 pm-8:46 pm

1 stop14h 46m

$722

GreenvilleMadrid

GSP Greenville - MAD Madrid Barajas

GSPMAD

Greenville

Tue 12/8

3:03 pm-7:45 am

1 stop10h 42m

Madrid Barajas

Tue 12/15

1:25 pm-1:26 pm

2 stops30h 01m

$724

Quickest round-trip

Myrtle BeachMadrid

MYR Myrtle Beach Intl - MAD Madrid Barajas

MYRMAD

Myrtle Beach Intl

Wed 4/14

12:57 pm-9:35 am

1 stop14h 38m

Madrid Barajas

Wed 4/28

3:25 pm-9:56 pm

1 stop12h 31m

$724

GreenvilleMadrid

GSP Greenville - MAD Madrid Barajas

GSPMAD

Greenville

Mon 11/23

12:12 pm-9:45 am

1 stop15h 33m

Madrid Barajas

Tue 12/8

9:20 am-7:56 pm

2 stops16h 36m

$725

GreenvilleMadrid

GSP Greenville - MAD Madrid Barajas

GSPMAD

Greenville

Mon 11/23

8:11 am-7:20 am

2 stops17h 09m

Madrid Barajas

Tue 12/8

9:20 am-7:56 pm

2 stops16h 36m

$725

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from South Carolina to Spain

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Other information

What is the cheapest month to fly to Spain?

If you don’t want to visit Spain in January, then you should wait until February to fly from South Carolina, when ticket prices are also cheap, with an average price of $577.

Can stopping save me money on South Carolina to Spain flights?

You could potentially save up to 33% on your flight if you consider stops on a South Carolina to Spain flight.

Cheap South Carolina to Spain flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from South Carolina to Spain

Best Price Found	$341
Fastest flight time	7h 40m
Direct flights	None

The best one-way flight to Spain from South Carolina in the past 72 hours is $341. The best round-trip flight deal from South Carolina to Spain found on momondo in the last 72 hours is $677.

The fastest flight from South Carolina to Spain takes 7h 40m

There are no direct flights from South Carolina to Spain. There are no popular flight routes from South Carolina to Spain.

Search flight deals

Frequently asked questions about flying from South Carolina to Spain

When did momondo last update prices for flights from South Carolina to Spain?
Prices for flights from South Carolina to Spain refresh daily.
How many operators does momondo search for flights from South Carolina to Spain?
There are 6 operators available for flights from South Carolina to Spain as of October 2026.
How old do you have to be to fly from South Carolina to Spain?
Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from South Carolina to Spain.
What documentation or ID do you need to fly to Spain?
The required travel and health documents for your Spain trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Spain. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from South Carolina to Spain

Compare and see reviews for airlines that fly from South Carolina to Spain with momondo

Airline	Rating	Free Cancellation	Price
Delta	PriceFrom $435	Free Cancellation	Rating 7.8 8,683 reviews	Search Delta flights
KLM	PriceFrom $439	Free Cancellation	Rating 7.8 1,597 reviews	Search KLM flights
British Airways	PriceFrom $481	Free Cancellation	Rating 6.7 8,274 reviews	Search British Airways flights
American Airlines	PriceFrom $499	Free Cancellation	Rating 7.0 12,191 reviews	Search American Airlines flights
United Airlines	PriceFrom $533	Free Cancellation	Rating 7.3 10,443 reviews	Search United Airlines flights
Virgin Atlantic	PriceFrom $1,241	Free Cancellation	Rating 7.5 697 reviews	Search Virgin Atlantic flights
Scandinavian Airlines	PriceFrom $1,601	Free Cancellation	Rating 7.4 2,028 reviews	Search Scandinavian Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from South Carolina to Spain?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from South Carolina to Spain for you.

Can I find flights from South Carolina to Spain with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Spain from South Carolina with this policy.

How can momondo help me find flights from South Carolina to Spain?

momondo provides multiple filters to help you find the best flight to Spain from South Carolina. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from South Carolina to Spain right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Spain, momondo offers a useful price alert feature which will track prices for flights to Spain from South Carolina and alert you when they change.