Cheap flights from South Carolina to Italy from $216

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from South Carolina to Italy departing on 4/15. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

Discover deals from 900+ travel sites with momondo.

Save money when you book flights with momondo

Big names and deals

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Price Alerts

Not ready to book? to track prices.

Find the cheapest flights from South Carolina to Italy

Cheap round-trip flights

Enter your travel dates to find the best prices.
Air Canada Logo
7:50 am - 8:55 am
CLT
-
MXP
20h 05m2 stops
Air Canada Logo
12:05 pm - 2:11 pm
MXP
-
CLT
31h 06m2 stops
$429Air Canada
Mon, Mar 9 - Tue, Mar 17
Lufthansa Logo
6:50 pm - 12:35 pm
CLT
-
MXP
11h 45m1 stop
Lufthansa Logo
6:05 am - 4:55 pm
MXP
-
CLT
16h 50m1 stop
$430Lufthansa
Mon, Feb 2 - Fri, Feb 13
American Airlines Logo
7:20 pm - 7:50 pm
CLT
-
MXP
19h 30m1 stop
American Airlines Logo
10:25 am - 9:00 pm
MXP
-
CLT
15h 35m1 stop
$434American Airlines
Mon, Mar 9 - Tue, Mar 17
British Airways Logo
7:03 pm - 7:45 pm
CLT
-
MXP
43h 42m2 stops
British Airways Logo
10:25 am - 9:00 pm
MXP
-
CLT
15h 35m1 stop
$435British Airways
Mon, Mar 9 - Tue, Mar 17
American Airlines Logo
11:40 pm - 8:50 pm
CLT
-
MXP
15h 10m1 stop
American Airlines Logo
11:05 am - 9:29 pm
MXP
-
CLT
16h 24m2 stops
$438American Airlines
Wed, Apr 15 - Wed, Apr 22
Multiple Airlines Logo
7:50 am - 9:55 am
CLT
-
MXP
20h 05m2 stops
Multiple Airlines Logo
6:05 am - 4:55 pm
MXP
-
CLT
16h 50m1 stop
$439Multiple Airlines
Mon, Feb 2 - Fri, Feb 13
Multiple Airlines Logo
8:25 pm - 4:55 pm
CLT
-
VCE
14h 30m1 stop
Multiple Airlines Logo
6:20 am - 4:05 pm
VCE
-
CLT
15h 45m1 stop
$440Multiple Airlines
Sun, Jan 18 - Tue, Feb 3
KLM Logo
12:43 pm - 8:05 am
CLT
-
MXP
14h 22m1 stop
KLM Logo
11:00 am - 10:38 pm
MXP
-
CLT
16h 38m1 stop
$442KLM
Mon, Mar 9 - Tue, Mar 17
KLM Logo
10:15 am - 10:20 am
CLT
-
VCE
19h 05m1 stop
KLM Logo
12:20 pm - 10:38 pm
VCE
-
CLT
15h 18m1 stop
$443KLM
Wed, Mar 18 - Wed, Mar 25
British Airways Logo
6:30 pm - 2:30 pm
CLT
-
LIN
14h 00m2 stops
British Airways Logo
7:25 am - 9:15 pm
LIN
-
CLT
19h 50m2 stops
$445British Airways
Wed, Feb 25 - Tue, Mar 3

Lufthansa flights from South Carolina to Italy

Our best Lufthansa deals on South Carolina to Italy flight tickets
Lufthansa
Feb 2
CLT6:50 pmCharlotte Douglas
11h 45m
1 stop
MXP12:35 pmMilan Malpensa
Feb 13
MXP6:05 amMilan Malpensa
16h 50m
1 stop
CLT4:55 pmCharlotte Douglas
$430
Lufthansa
Feb 20
CHS11:15 amCharleston
14h 40m
1 stop
FCO7:55 amRome Fiumicino
Feb 27
FCO9:45 amRome Fiumicino
17h 42m
1 stop
CHS9:27 pmCharleston
$433
Lufthansa
Feb 26
SAV2:15 pmSavannah/Hilton Head
23h 45m
2 stops
FCO8:00 pmRome Fiumicino
Mar 5
FCO10:30 amRome Fiumicino
19h 26m
1 stop
SAV11:56 pmSavannah/Hilton Head
$465

SWISS flights from South Carolina to Italy

Our best SWISS deals on South Carolina to Italy flight tickets
SWISS
Feb 12
CLT6:50 pmCharlotte Douglas
32h 55m
2 stops
VCE9:45 amVenice Marco Polo
Feb 18
VCE6:55 amVenice Marco Polo
39h 22m
2 stops
CLT4:17 pmCharlotte Douglas
$573
SWISS
Feb 12
CLT6:50 pmCharlotte Douglas
32h 55m
2 stops
VCE9:45 amVenice Marco Polo
Feb 18
VCE6:55 amVenice Marco Polo
15h 22m
2 stops
CLT4:17 pmCharlotte Douglas
$578

momondo Fare Finder

 
Customize your flight search to find flights from South Carolina to Italy that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated January 8, 2026.
Use the filters below to find and compare flights from South Carolina to Italy that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

CharlotteMilan

CLT - MXP

CLTMXP

Charlotte Douglas

Mon 3/9

7:50 am-8:55 am

2 stops20h 05m

Milan Malpensa

Tue 3/17

12:05 pm-2:11 pm

2 stops31h 06m

$429

CharlotteMilan

CLT - MXP

CLTMXP

Charlotte Douglas

Mon 2/2

6:50 pm-12:35 pm

1 stop11h 45m

Milan Malpensa

Fri 2/13

6:05 am-4:55 pm

1 stop16h 50m

$430

CharlotteMilan

CLT - MXP

CLTMXP

Charlotte Douglas

Mon 3/9

7:20 pm-7:50 pm

1 stop19h 30m

Milan Malpensa

Tue 3/17

10:25 am-9:00 pm

1 stop15h 35m

$434

CharlotteMilan

CLT - MXP

CLTMXP

Charlotte Douglas

Mon 3/9

7:03 pm-7:45 pm

2 stops43h 42m

Milan Malpensa

Tue 3/17

10:25 am-9:00 pm

1 stop15h 35m

$435

CharlotteMilan

CLT - MXP

CLTMXP

Charlotte Douglas

Wed 4/15

11:40 pm-8:50 pm

1 stop15h 10m

Milan Malpensa

Wed 4/22

11:05 am-9:29 pm

2 stops16h 24m

$438

CharlotteMilan

CLT - MXP

CLTMXP

Charlotte Douglas

Mon 2/2

7:50 am-9:55 am

2 stops20h 05m

Milan Malpensa

Fri 2/13

6:05 am-4:55 pm

1 stop16h 50m

$439

CharlotteVenice

CLT - VCE

CLTVCE

Charlotte Douglas

Sun 1/18

8:25 pm-4:55 pm

1 stop14h 30m

Venice Marco Polo

Tue 2/3

6:20 am-4:05 pm

1 stop15h 45m

$440

CharlotteMilan

CLT - MXP

CLTMXP

Charlotte Douglas

Mon 3/9

12:43 pm-8:05 am

1 stop14h 22m

Milan Malpensa

Tue 3/17

11:00 am-10:38 pm

1 stop16h 38m

$442

CharlotteVenice

CLT - VCE

CLTVCE

Charlotte Douglas

Wed 3/18

10:15 am-10:20 am

1 stop19h 05m

Venice Marco Polo

Wed 3/25

12:20 pm-10:38 pm

1 stop15h 18m

$443

CharlotteMilan

CLT - LIN

CLTLIN

Charlotte Douglas

Wed 2/25

6:30 pm-2:30 pm

2 stops14h 00m

Milan Linate

Tue 3/3

7:25 am-9:15 pm

2 stops19h 50m

$445

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
1
2

See travel insights to Italy from

How to get the cheapest flight ticket from South Carolina to Italy

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Italy?

The cheapest month to fly to Italy from South Carolina is in February. Flight prices, which tend to average around $682, are often lower during this time because this is during the off-season. If you aren’t able to travel during the month of February, then book flights to Italy from South Carolina during January instead. Flights to Italy in January, while not as cheap as those in February, still average around $703.

Can stopping save me money on South Carolina to Italy flights?

You could potentially save up to 12% on your flight if you consider stops on a South Carolina to Italy flight.

Cheap South Carolina to Italy flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from South Carolina to Italy

Fastest flight time

9h 05m

Direct flights

Every day

Airports in Italy

416 airports
The fastest flight from South Carolina to Italy takes 9h 05m
Direct flights go from South Carolina to Italy every day.
There are 416 airports in Italy. From South Carolina there are direct flights to Rome Fiumicino (FCO).
  • When did momondo last update prices for flights from South Carolina to Italy?

    Prices for flights from South Carolina to Italy refresh daily.

  • How many operators does momondo search for flights from South Carolina to Italy?

  • How old do you have to be to fly from South Carolina to Italy?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from South Carolina to Italy.

  • What documentation or ID do you need to fly to Italy?

    The required travel and health documents for your Italy trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Italy. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from South Carolina to Italy

Compare and see reviews for airlines that fly from South Carolina to Italy with momondo
Airline
Rating
Free Cancellation
Price
United AirlinesPriceFrom $307Free CancellationRating
7.4
9,141 reviews
Search United Airlines flights
DeltaPriceFrom $511Free CancellationRating
7.9
8,029 reviews
Search Delta flights
KLMPriceFrom $555Free CancellationRating
7.7
1,434 reviews
Search KLM flights
LufthansaPriceFrom $591Free CancellationRating
6.8
7,696 reviews
Search Lufthansa flights
British AirwaysPriceFrom $609Free CancellationRating
6.7
7,657 reviews
Search British Airways flights
American AirlinesPriceFrom $674Free CancellationRating
7.2
11,095 reviews
Search American Airlines flights
Air FrancePriceFrom $957Free CancellationRating
7.4
1,519 reviews
Search Air France flights

Why use momondo?

Why should I use momondo to find a flight deal from South Carolina to Italy?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from South Carolina to Italy. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from South Carolina to Italy with flexible booking policies on momondo?

Yes. All flights to Italy from South Carolina on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from South Carolina to Italy?

Once all potential South Carolina to Italy flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from South Carolina to Italy right now. Can momondo alert me if prices change?

Price alerts on flights to Italy from South Carolina are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

An easier way to manage your Italy trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.
1 adult
Sat 2/7
Sat 2/14

Find better results for your trip to Italy

Popular cities in Italy

Popular flights according to clicks in the last 7 days on momondo