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Flights to Sao Tome Is

$761 Cheap flights to São Tomé

1 adult
1 adult, Economy, 0 bags

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Find the cheapest flights from the United States to São Tomé

Cheap round-trip flights

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TAP AIR PORTUGAL Logo
5:15 pm - 5:45 pmEWR  Newark-TMS Sao Tome Is
20h 30m2 stops Lisbon Humberto Delgado Accra Kotoka
TAP AIR PORTUGAL Logo
7:40 pm - 9:00 pmTMS  Sao Tome Is-EWR Newark
29h 20m2 stops Accra Kotoka Lisbon Humberto Delgado
$1,566TAP AIR PORTUGAL
Thu, Apr 22 - Sun, Apr 25
TAP AIR PORTUGAL Logo
12:55 am - 5:45 pmEWR  Newark-TMS Sao Tome Is
36h 50m3 stops Porto Lisbon Humberto Delgado Accra Kotoka
TAP AIR PORTUGAL Logo
7:40 pm - 9:00 pmTMS  Sao Tome Is-EWR Newark
29h 20m2 stops Accra Kotoka Lisbon Humberto Delgado
$1,571TAP AIR PORTUGAL
Wed, Apr 21 - Sun, Apr 25
Multiple Airlines Logo
12:25 am - 5:45 pmEWR  Newark-TMS Sao Tome Is
37h 20m3 stops Istanbul Lisbon Humberto Delgado Accra Kotoka
Multiple Airlines Logo
7:40 pm - 10:30 pmTMS  Sao Tome Is-EWR Newark
30h 50m3 stops Accra Kotoka Lisbon Humberto Delgado Istanbul
$1,584Multiple Airlines
Wed, Apr 21 - Sun, Apr 25
Multiple Airlines Logo
5:15 pm - 5:45 pmEWR  Newark-TMS Sao Tome Is
20h 30m1 stop Lisbon Humberto Delgado
Multiple Airlines Logo
7:40 pm - 7:03 pmTMS  Sao Tome Is-EWR Newark
27h 23m2 stops Lisbon Humberto Delgado Toronto Pearson Intl
$1,939Multiple Airlines
Thu, Apr 22 - Sun, Apr 25
TAP AIR PORTUGAL Logo
5:15 pm - 5:45 pmEWR  Newark-TMS Sao Tome Is
20h 30m1 stop Lisbon Humberto Delgado
TAP AIR PORTUGAL Logo
7:40 pm - 3:30 pmTMS  Sao Tome Is-EWR Newark
23h 50m1 stop Lisbon Humberto Delgado
$1,974TAP AIR PORTUGAL
Thu, Apr 22 - Sun, Apr 25
Multiple Airlines Logo
2:50 pm - 6:15 pmSEA  Seattle/Tacoma Intl-TMS Sao Tome Is
43h 25m3 stops Munich Franz Josef Strauss Lisbon Humberto Delgado Accra Kotoka
Multiple Airlines Logo
8:00 pm - 8:59 pmTMS  Sao Tome Is-SEA Seattle/Tacoma Intl
32h 59m3 stops Accra Kotoka Lisbon Humberto Delgado Toronto Pearson Intl
$2,125Multiple Airlines
Fri, Dec 4 - Sun, Dec 13
Multiple Airlines Logo
1:50 pm - 5:30 pmSEA  Seattle/Tacoma Intl-TMS Sao Tome Is
43h 40m2 stops Frankfurt am Main Lisbon Humberto Delgado
Multiple Airlines Logo
8:00 pm - 8:59 pmTMS  Sao Tome Is-SEA Seattle/Tacoma Intl
32h 59m3 stops Accra Kotoka Lisbon Humberto Delgado Toronto Pearson Intl
$2,146Multiple Airlines
Thu, Dec 3 - Sun, Dec 13
Multiple Airlines Logo
7:05 pm - 6:15 pmSEA  Seattle/Tacoma Intl-TMS Sao Tome Is
63h 10m3 stops Istanbul Lisbon Humberto Delgado Accra Kotoka
Multiple Airlines Logo
8:00 pm - 5:10 pmTMS  Sao Tome Is-SEA Seattle/Tacoma Intl
53h 10m3 stops Accra Kotoka Lisbon Humberto Delgado Istanbul
$2,762Multiple Airlines
Thu, Dec 3 - Sun, Dec 13
Multiple Airlines Logo
7:00 am - 5:30 pmPDX  Portland-TMS Sao Tome Is
26h 30m3 stops Vancouver Intl Montreal Pierre Elliott Trudeau Intl Lisbon Humberto Delgado
Multiple Airlines Logo
8:00 pm - 8:46 pmTMS  Sao Tome Is-PDX Portland
32h 46m3 stops Lisbon Humberto Delgado London Gatwick Vancouver Intl
$3,246Multiple Airlines
Fri, Jan 15 - Sun, Jan 24
Multiple Airlines Logo
7:00 am - 5:30 pmPDX  Portland-TMS Sao Tome Is
26h 30m3 stops Vancouver Intl Montreal Pierre Elliott Trudeau Intl Lisbon Humberto Delgado
Multiple Airlines Logo
8:00 pm - 3:50 pmTMS  Sao Tome Is-PDX Portland
27h 50m2 stops Lisbon Humberto Delgado London Gatwick
$3,362Multiple Airlines
Fri, Jan 15 - Sun, Jan 24

momondo Fare Finder

 
Use the filters below to find and compare flights to São Tomé that are best for you.

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Route

Depart

Return

Price

Cheapest round-trip

NewarkSão Tomé

EWR Newark - TMS Sao Tome Is

EWRTMS

Newark

Thu 4/22

5:15 pm-5:45 pm

2 stops20h 30m

Sao Tome Is

Sun 4/25

7:40 pm-9:00 pm

2 stops29h 20m

$1,566

NewarkSão Tomé

EWR Newark - TMS Sao Tome Is

EWRTMS

Newark

Wed 4/21

12:55 am-5:45 pm

3 stops36h 50m

Sao Tome Is

Sun 4/25

7:40 pm-9:00 pm

2 stops29h 20m

$1,571

NewarkSão Tomé

EWR Newark - TMS Sao Tome Is

EWRTMS

Newark

Wed 4/21

12:25 am-5:45 pm

3 stops37h 20m

Sao Tome Is

Sun 4/25

7:40 pm-10:30 pm

3 stops30h 50m

$1,584

NewarkSão Tomé

EWR Newark - TMS Sao Tome Is

EWRTMS

Newark

Thu 4/22

5:15 pm-5:45 pm

1 stop20h 30m

Sao Tome Is

Sun 4/25

7:40 pm-7:03 pm

2 stops27h 23m

$1,939
Quickest round-trip

NewarkSão Tomé

EWR Newark - TMS Sao Tome Is

EWRTMS

Newark

Thu 4/22

5:15 pm-5:45 pm

1 stop20h 30m

Sao Tome Is

Sun 4/25

7:40 pm-3:30 pm

1 stop23h 50m

$1,974

SeattleSão Tomé

SEA Seattle/Tacoma Intl - TMS Sao Tome Is

SEATMS

Seattle/Tacoma Intl

Fri 12/4

2:50 pm-6:15 pm

3 stops43h 25m

Sao Tome Is

Sun 12/13

8:00 pm-8:59 pm

3 stops32h 59m

$2,125

SeattleSão Tomé

SEA Seattle/Tacoma Intl - TMS Sao Tome Is

SEATMS

Seattle/Tacoma Intl

Thu 12/3

1:50 pm-5:30 pm

2 stops43h 40m

Sao Tome Is

Sun 12/13

8:00 pm-8:59 pm

3 stops32h 59m

$2,146

SeattleSão Tomé

SEA Seattle/Tacoma Intl - TMS Sao Tome Is

SEATMS

Seattle/Tacoma Intl

Thu 12/3

7:05 pm-6:15 pm

3 stops63h 10m

Sao Tome Is

Sun 12/13

8:00 pm-5:10 pm

3 stops53h 10m

$2,762

PortlandSão Tomé

PDX Portland - TMS Sao Tome Is

PDXTMS

Portland

Fri 1/15

7:00 am-5:30 pm

3 stops26h 30m

Sao Tome Is

Sun 1/24

8:00 pm-8:46 pm

3 stops32h 46m

$3,246

PortlandSão Tomé

PDX Portland - TMS Sao Tome Is

PDXTMS

Portland

Fri 1/15

7:00 am-5:30 pm

3 stops26h 30m

Sao Tome Is

Sun 1/24

8:00 pm-3:50 pm

2 stops27h 50m

$3,362

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 15 resultsSorted by cheapest first
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See travel insights to São Tomé from

São Tomé flights insights and trends

Explore insights for your São Tomé flight to craft the best travel plan

How long does it take to fly to São Tomé?

Flight times vary depending on what airport in United States you fly out of and what airport in São Tomé you fly into. For example, flying from Los Angeles to Sao Tome Is takes 27h 45m on average. On the other hand, flying from Miami to Sao Tome Is takes 20h 40m on average. Keep in mind that it’s always quicker to opt for a non-stop flight, so be sure to check momondo if there are any available for your route.

Cheap São Tomé flight deals and tips

Summary info about São Tomé flight prices, duration and airlines

Best One-Way Price

$761

Best Round-Trip Price

$2,125

Fastest flight time

54h 25m
The best one-way flight price to São Tomé from United States in the last 5 days is $761 (Newark to Sao Tome Is).
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The best round-trip flight price to São Tomé from United States in the last 5 days is $2,125 (Seattle/Tacoma Intl to Sao Tome Is).
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The fastest flight to São Tomé from United States takes 54h 25m (Newark to Sao Tome Is).
Search Deals

Frequently asked questions about flying to São Tomé

When did momondo last update prices for flights to Sao Tome Is Airport?

Prices for flights to Sao Tome Is Airport are refreshed on a daily basis.

How many operators does momondo search for flights to Sao Tome Is Airport?

There are 3 operators available for flights to Sao Tome Is Airport as of November 2026.

How old do you have to be to fly to Sao Tome Is Airport?

Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel to Sao Tome Is Airport.

What documentation or ID do you need to fly to Sao Tome Is Airport?

The travel and health documents required for your trip to Sao Tome Is Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Sao Tome Is Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Why use momondo?

Why should I use momondo to find a flight deal to São Tomé?

We help find the flight that best suits your needs; momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight for you.

Can I find flights to São Tomé with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to São Tomé with this policy.

How can momondo help me find flights to São Tomé?

momondo provides multiple filters to help you find the best flight to São Tomé. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight to São Tomé right now. Can momondo alert me if prices change?

If you are simply researching potential flights to São Tomé, momondo offers a useful price alert feature which will track prices for flights to São Tomé and alert you when they change.

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Popular flights to São Tomé

Washington, D.C. to Sao Tome Is Flightsfrom $1,793
Miami to Sao Tome Is Flightsfrom $3,683
Los Angeles to Sao Tome Is Flightsfrom $2,967