Cheap flights from Santa Ana to Detroit from $80

The cheapest month to fly to Detroit Metropolitan Wayne County Airport from Santa Ana is in August. Flight prices, which tend to average around $302, are often lower during this time because this is during the off-season. If you aren’t able to travel during the month of August, then book flights to Detroit Metropolitan Wayne County Airport from Santa Ana during September instead. Flights to Detroit Metropolitan Wayne County Airport in September, while not as cheap as those in August, still average around $359.

The cheapest day to depart from Santa Ana to Detroit Metropolitan Wayne County Airport is on a Wednesday when prices can be found for as low as $346. Be sure to avoid booking your departure on a Sunday as prices are generally higher than usual. According to our data, the average ticket price to Detroit Metropolitan Wayne County Airport on Sunday is $426.

Flying to Detroit Metropolitan Wayne County Airport from Santa Ana at noon is the least expensive time of day to depart. momondo users have found prices as low as $331 when looking at flights departing at noon. Flights to Detroit Metropolitan Wayne County Airport are more costly in the morning, with an average ticket price of $397. Departure times in the morning fall within the peak daily travel times, which is why tickets can be more expensive.

Fly from Santa Ana J. Wayne/Orange Cnty to Detroit Metropolitan Wayne County for the best Santa Ana J. Wayne/Orange Cnty - Detroit Metropolitan Wayne County flight prices

You are more likely to see cheaper flights to Detroit Metropolitan Wayne County Airport from Santa Ana when booking weeks ahead of your departure date. In general, you can expect to find flights to Detroit Metropolitan Wayne County Airport for around $503 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Detroit Metropolitan Wayne County Airport from Santa Ana for as low as $289 on momondo.

There are 4 cabin classes available to choose from on Santa Ana J. Wayne/Orange Cnty to Detroit Metropolitan Wayne County flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

No. A direct flight is the cheapest option for a flight between Santa Ana to Detroit Metropolitan Wayne County Airport.

As of April 2026, prices for Santa Ana to Detroit Metropolitan Wayne County Airport flights are approximately 0% more expensive when compared to flights at the same time last year.

Alaska Airlines and Delta are the most popular carriers operating from Santa Ana J. Wayne/Orange Cnty to Detroit Metropolitan Wayne County

Spirit Airlines, Delta and Frontier are the top three most popular airlines that fly to Detroit Metropolitan Wayne County Airport from Santa Ana according to our data. Spirit Airlines is the first choice among our users, with 54% of people opting to fly with this airline when traveling to Detroit Metropolitan Wayne County Airport. Keep in mind that there are 6 different airlines that fly to Detroit Metropolitan Wayne County Airport on a routine basis, so you have a few additional options to choose from.

Las Vegas (LAS) was the most common stop: 67% of momondo users choosing 1-stop flights on this route connected there.

Flights via Las Vegas (LAS) offer the lowest average round-trip price of $216.

Flights connecting via Chicago (ORD) have the shortest average one-way travel time: 7h 17m.

Chicago (ORD) has the shortest average layover time for this route: 1h 24m.

As of April 2026, 1 flights take off from Santa Ana and land in Detroit Metropolitan Wayne County Airport each day. The most common flight departure time for this route is 12:00PM, with 100% of daily flights taking off in the afternoon.

The number of flights available between Santa Ana and Detroit Metropolitan Wayne County Airport is 12 per week as of April 2026. The most frequent departure day is Mon, with 17% of weekly flights leaving on this day.