Cheap flights from San Francisco to Sao Paulo from $426

The cheapest month to fly to Sao Paulo from San Francisco is in February. Flight prices, which tend to average around $747, are often lower during this time because this is during the off-season. If you don’t want to visit Sao Paulo in February, then you should wait until March to fly from San Francisco, when ticket prices are also cheap, with an average price of $802.

You are more likely to see cheaper flights to Sao Paulo from San Francisco when booking weeks ahead of your departure date. In general, you can expect to find flights to Sao Paulo for around $870 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Sao Paulo from San Francisco for as low as $782 on momondo.

You could potentially save up to 4% on your flight if you consider stops on a San Francisco to Sao Paulo flight.

As of September 2026, prices for San Francisco to Sao Paulo flights are approximately 19% more expensive when compared to flights at the same time last year.

Copa Airlines, Delta, and Azul are the most popular carriers operating from San Francisco to Sao Paulo

United Airlines, Copa Airlines and LATAM Airlines are the top three most popular airlines that fly to Sao Paulo from San Francisco according to our data. United Airlines is the first choice among our users, with 34% of people opting to fly with this airline when traveling to Sao Paulo. Keep in mind that there are 8 different airlines that fly to Sao Paulo on a routine basis, so you have a few additional options to choose from.

Panama City (PTY) was the most common stop: 34% of momondo users choosing 1-stop flights on this route connected there.

Flights via Montreal (YUL) offer the lowest average round-trip price of $715.

Flights connecting via Miami (MIA) have the shortest average one-way travel time: 14h 40m.

Houston (IAH) has the shortest average layover time for this route: 1h 19m.