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Cheap flights from San Francisco to Santiago de los Caballeros from $268

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from San Francisco to Santiago de los Caballeros departing on 6/6. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from San Francisco to Santiago de los Caballeros

Cheap round-trip flights

Enter your travel dates to find the best prices.
JetBlue Logo
10:50 pm - 1:05 pm
SFO
-
STI
11h 15m
1 stop
JetBlue Logo
8:48 pm - 9:25 am
STI
-
SFO
15h 37m
1 stop
$525JetBlue
lun., may. 4 - jue., may. 7
JetBlue Logo
8:44 pm - 12:08 pm
SFO
-
STI
12h 24m
1 stop
JetBlue Logo
8:57 am - 11:51 pm
STI
-
SFO
17h 54m
1 stop
$539JetBlue
mié., may. 6 - mié., may. 13
JetBlue Logo
10:50 pm - 7:03 pm
SFO
-
STI
17h 13m
1 stop
JetBlue Logo
9:15 am - 11:55 pm
STI
-
SFO
17h 40m
1 stop
$592JetBlue
vie., abr. 17 - vie., abr. 24
JetBlue Logo
8:35 pm - 8:00 am
SFO
-
STI
8h 25m
1 stop
JetBlue Logo
6:38 pm - 9:11 am
STI
-
SFO
17h 33m
1 stop
$593JetBlue
mar., jun. 16 - mar., jun. 23
JetBlue Logo
10:29 pm - 1:05 pm
SFO
-
STI
11h 36m
1 stop
JetBlue Logo
7:00 am - 7:22 pm
STI
-
SFO
15h 22m
1 stop
$595JetBlue
lun., abr. 13 - jue., abr. 16
JetBlue Logo
8:35 pm - 8:00 am
SFO
-
STI
8h 25m
1 stop
JetBlue Logo
6:58 pm - 10:06 am
STI
-
SFO
18h 08m
1 stop
$629JetBlue
lun., jun. 15 - lun., ago. 31
JetBlue Logo
8:35 pm - 8:00 am
SFO
-
STI
8h 25m
1 stop
JetBlue Logo
9:10 am - 9:56 am
STI
-
SFO
27h 46m
1 stop
$642JetBlue
lun., jun. 15 - lun., ago. 31
JetBlue Logo
10:29 pm - 1:05 pm
SFO
-
STI
11h 36m
1 stop
JetBlue Logo
6:00 am - 7:22 pm
STI
-
SFO
16h 22m
1 stop
$664JetBlue
lun., abr. 13 - jue., abr. 16
JetBlue Logo
8:35 pm - 8:00 am
SFO
-
STI
8h 25m
1 stop
JetBlue Logo
9:10 am - 9:56 am
STI
-
SFO
27h 46m
1 stop
$675JetBlue
lun., jun. 15 - lun., ago. 31
JetBlue Logo
11:10 am - 8:02 am
SFO
-
STI
17h 52m
1 stop
JetBlue Logo
8:31 am - 11:56 pm
STI
-
SFO
18h 25m
1 stop
$698JetBlue
jue., abr. 9 - vie., abr. 17

JetBlue flights from San Francisco to Santiago de los Caballeros

Our best JetBlue deals on San Francisco to Santiago de los Caballeros flight tickets
JetBlue
May 4
SFO10:50 pmSan Francisco
11h 15m
1 stop
STI1:05 pmSantiago de los Caballeros
May 7
STI8:48 pmSantiago de los Caballeros
15h 37m
1 stop
SFO9:25 amSan Francisco
$525
JetBlue
May 6
SFO8:44 pmSan Francisco
12h 24m
1 stop
STI12:08 pmSantiago de los Caballeros
May 13
STI8:57 amSantiago de los Caballeros
17h 54m
1 stop
SFO11:51 pmSan Francisco
$539
JetBlue
Apr 17
SFO10:50 pmSan Francisco
17h 13m
1 stop
STI7:03 pmSantiago de los Caballeros
Apr 24
STI9:15 amSantiago de los Caballeros
17h 40m
1 stop
SFO11:55 pmSan Francisco
$592

American Airlines flights from San Francisco to Santiago de los Caballeros

Our best American Airlines deals on San Francisco to Santiago de los Caballeros flight tickets
American Airlines
Jun 15
SFO9:50 pmSan Francisco
13h 48m
1 stop
STI2:38 pmSantiago de los Caballeros
Aug 31
STI7:00 amSantiago de los Caballeros
18h 58m
1 stop
SFO10:58 pmSan Francisco
$729
American Airlines
Jun 15
SFO9:50 pmSan Francisco
13h 48m
1 stop
STI2:38 pmSantiago de los Caballeros
Aug 31
STI7:00 amSantiago de los Caballeros
17h 16m
2 stops
SFO9:16 pmSan Francisco
$733
American Airlines
Jun 16
SFO11:29 pmSan Francisco
18h 44m
2 stops
STI9:13 pmSantiago de los Caballeros
Jun 23
STI3:38 pmSantiago de los Caballeros
11h 21m
1 stop
SFO11:59 pmSan Francisco
$758

momondo Fare Finder

 
Customize your flight search to find flights from San Francisco to Santiago de los Caballeros that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated marzo 23, 2026.
Use the filters below to find and compare flights from San Francisco to Santiago de los Caballeros that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

San FranciscoSantiago de los Caballeros

SFO - STI

SFOSTI

San Francisco

lun. 5/4

10:50 pm-1:05 pm

1 stop11h 15m

Santiago de los Caballeros

jue. 5/7

8:48 pm-9:25 am

1 stop15h 37m

$525

San FranciscoSantiago de los Caballeros

SFO - STI

SFOSTI

San Francisco

mié. 5/6

8:44 pm-12:08 pm

1 stop12h 24m

Santiago de los Caballeros

mié. 5/13

8:57 am-11:51 pm

1 stop17h 54m

$539

San FranciscoSantiago de los Caballeros

SFO - STI

SFOSTI

San Francisco

vie. 4/17

10:50 pm-7:03 pm

1 stop17h 13m

Santiago de los Caballeros

vie. 4/24

9:15 am-11:55 pm

1 stop17h 40m

$592
Quickest round-trip

San FranciscoSantiago de los Caballeros

SFO - STI

SFOSTI

San Francisco

mar. 6/16

8:35 pm-8:00 am

1 stop8h 25m

Santiago de los Caballeros

mar. 6/23

6:38 pm-9:11 am

1 stop17h 33m

$593

San FranciscoSantiago de los Caballeros

SFO - STI

SFOSTI

San Francisco

lun. 4/13

10:29 pm-1:05 pm

1 stop11h 36m

Santiago de los Caballeros

jue. 4/16

7:00 am-7:22 pm

1 stop15h 22m

$595

San FranciscoSantiago de los Caballeros

SFO - STI

SFOSTI

San Francisco

lun. 6/15

8:35 pm-8:00 am

1 stop8h 25m

Santiago de los Caballeros

lun. 8/31

6:58 pm-10:06 am

1 stop18h 08m

$629

San FranciscoSantiago de los Caballeros

SFO - STI

SFOSTI

San Francisco

lun. 6/15

8:35 pm-8:00 am

1 stop8h 25m

Santiago de los Caballeros

lun. 8/31

9:10 am-9:56 am

1 stop27h 46m

$642

San FranciscoSantiago de los Caballeros

SFO - STI

SFOSTI

San Francisco

lun. 4/13

10:29 pm-1:05 pm

1 stop11h 36m

Santiago de los Caballeros

jue. 4/16

6:00 am-7:22 pm

1 stop16h 22m

$664

San FranciscoSantiago de los Caballeros

SFO - STI

SFOSTI

San Francisco

lun. 6/15

8:35 pm-8:00 am

1 stop8h 25m

Santiago de los Caballeros

lun. 8/31

9:10 am-9:56 am

1 stop27h 46m

$675

San FranciscoSantiago de los Caballeros

SFO - STI

SFOSTI

San Francisco

jue. 4/9

11:10 am-8:02 am

1 stop17h 52m

Santiago de los Caballeros

vie. 4/17

8:31 am-11:56 pm

1 stop18h 25m

$698

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Santiago de los Caballeros from

How to get the cheapest flight ticket from San Francisco to Santiago de los Caballeros

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Can stopping save me money on San Francisco to Santiago de los Caballeros flights?

You could potentially save up to 30% on your flight if you consider stops on a San Francisco to Santiago de los Caballeros flight.

When to book flights from San Francisco to Santiago de los Caballeros

Are you open to changing your travel dates? Check out the ideal times to fly from San Francisco to Santiago de los Caballeros according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap San Francisco to Santiago de los Caballeros (SFO to STI) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from San Francisco to Santiago de los Caballeros

Fastest flight time

8h 25m

Direct flights

None
The fastest flight from San Francisco to Santiago de los Caballeros takes 8h 25m
There are no direct flights from San Francisco to Santiago de los Caballeros. There are no popular flight routes from San Francisco to Santiago de los Caballeros.
Search flight deals

  • How far is San Francisco to Santiago de los Caballeros by plane?

    A flight from San Francisco to Santiago de los Caballeros will travel around 3332.2 mi. A reasonable flight in good conditions will take 8h 25m.

  • When did momondo last update prices for flights from San Francisco Airport to Santiago de los Caballeros Airport?

    Prices for flights from San Francisco Airport to Santiago de los Caballeros Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from San Francisco Airport to Santiago de los Caballeros Airport?

  • How old do you have to be to fly from San Francisco Airport to Santiago de los Caballeros Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from San Francisco Airport to Santiago de los Caballeros Airport.

  • What documentation or ID do you need to fly to Santiago de los Caballeros Airport?

    The travel and health documents you'll need for your trip to Santiago de los Caballeros Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Santiago de los Caballeros Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from San Francisco to Santiago de los Caballeros?

Best airlines flying from San Francisco to Santiago de los Caballeros

Compare and see reviews for airlines that fly from San Francisco to Santiago de los Caballeros with momondo
Airline
Rating
Free Cancellation
Price
JetBluePriceFrom $319Free CancellationRating
7.2
2,908 reviews
Search JetBlue flights
American AirlinesPriceFrom $614Free CancellationRating
7.1
11,486 reviews
Search American Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from San Francisco to Santiago de los Caballeros?

Finding the right flight to Santiago de los Caballeros from San Francisco is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Santiago de los Caballeros quick and easy, saving you time and money.

Can I find flights from San Francisco to Santiago de los Caballeros with flexible booking policies on momondo?

Flights from San Francisco to Santiago de los Caballeros with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from San Francisco to Santiago de los Caballeros?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from San Francisco to Santiago de los Caballeros.

I’m not ready to book a flight from San Francisco to Santiago de los Caballeros right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of San Francisco to Santiago de los Caballeros flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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