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Cheap flights from San Francisco to Santiago de los Caballeros from $318

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from San Francisco to Santiago de los Caballeros departing on 8/28. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from San Francisco to Santiago de los Caballeros

Cheap round-trip flights

Enter your travel dates to find the best prices.
JetBlue Logo
11:10 pm - 1:27 pm
SFO
-
STI
11h 17m
1 stop
JetBlue Logo
3:49 pm - 11:19 pm
STI
-
SFO
10h 30m
1 stop
$632JetBlue
Mon, Sep 28 - Thu, Oct 1
JetBlue Logo
11:59 pm - 8:25 pm
SFO
-
STI
17h 26m
1 stop
JetBlue Logo
3:49 pm - 11:19 pm
STI
-
SFO
10h 30m
1 stop
$651JetBlue
Mon, Sep 28 - Thu, Oct 1
JetBlue Logo
11:59 pm - 8:25 pm
SFO
-
STI
17h 26m
1 stop
JetBlue Logo
3:49 pm - 11:19 pm
STI
-
SFO
10h 30m
1 stop
$656JetBlue
Mon, Sep 28 - Thu, Oct 1
JetBlue Logo
10:40 pm - 7:03 am
SFO
-
STI
29h 23m
1 stop
JetBlue Logo
8:13 am - 11:51 pm
STI
-
SFO
18h 38m
1 stop
$663JetBlue
Thu, Aug 13 - Fri, Aug 21
JetBlue Logo
10:40 pm - 3:01 pm
SFO
-
STI
13h 21m
1 stop
JetBlue Logo
8:13 am - 11:51 pm
STI
-
SFO
18h 38m
1 stop
$677JetBlue
Sun, Aug 16 - Sun, Aug 23
JetBlue Logo
10:59 am - 7:03 am
SFO
-
STI
17h 04m
1 stop
JetBlue Logo
8:13 am - 11:51 pm
STI
-
SFO
18h 38m
1 stop
$682JetBlue
Thu, Aug 13 - Fri, Aug 21
JetBlue Logo
7:59 am - 1:21 am
SFO
-
STI
14h 22m
1 stop
JetBlue Logo
3:44 pm - 11:30 pm
STI
-
SFO
10h 46m
1 stop
$684JetBlue
Thu, Oct 22 - Tue, Oct 27
JetBlue Logo
10:40 pm - 3:01 pm
SFO
-
STI
13h 21m
1 stop
JetBlue Logo
4:54 pm - 11:51 pm
STI
-
SFO
9h 57m
1 stop
$705JetBlue
Tue, Aug 18 - Tue, Aug 25
JetBlue Logo
10:10 pm - 1:21 am
SFO
-
STI
24h 11m
1 stop
JetBlue Logo
5:01 am - 9:48 am
STI
-
SFO
31h 47m
1 stop
$715JetBlue
Sat, Oct 3 - Sun, Oct 25
American Airlines Logo
10:59 pm - 2:12 pm
SFO
-
STI
12h 13m
1 stop
American Airlines Logo
3:16 pm - 11:59 pm
STI
-
SFO
11h 43m
1 stop
$720American Airlines
Thu, Oct 22 - Tue, Oct 27

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JetBlue flights from San Francisco to Santiago de los Caballeros

Our best JetBlue deals on San Francisco to Santiago de los Caballeros flight tickets
JetBlue
Sep 28
SFO11:10 pmSan Francisco
11h 17m
1 stop
STI1:27 pmSantiago de los Caballeros
Oct 1
STI3:49 pmSantiago de los Caballeros
10h 30m
1 stop
SFO11:19 pmSan Francisco
$632
JetBlue
Sep 28
SFO11:59 pmSan Francisco
17h 26m
1 stop
STI8:25 pmSantiago de los Caballeros
Oct 1
STI3:49 pmSantiago de los Caballeros
10h 30m
1 stop
SFO11:19 pmSan Francisco
$651
JetBlue
Sep 28
SFO11:59 pmSan Francisco
17h 26m
1 stop
STI8:25 pmSantiago de los Caballeros
Oct 1
STI3:49 pmSantiago de los Caballeros
10h 30m
1 stop
SFO11:19 pmSan Francisco
$656

American Airlines flights from San Francisco to Santiago de los Caballeros

Our best American Airlines deals on San Francisco to Santiago de los Caballeros flight tickets
American Airlines
Oct 22
SFO10:59 pmSan Francisco
12h 13m
1 stop
STI2:12 pmSantiago de los Caballeros
Oct 27
STI3:16 pmSantiago de los Caballeros
11h 43m
1 stop
SFO11:59 pmSan Francisco
$720
American Airlines
Aug 13
SFO5:00 pmSan Francisco
18h 35m
2 stops
STI2:35 pmSantiago de los Caballeros
Aug 21
STI7:00 amSantiago de los Caballeros
15h 13m
2 stops
SFO7:13 pmSan Francisco
$725
American Airlines
Aug 16
SFO7:30 amSan Francisco
10h 37m
1 stop
STI9:07 pmSantiago de los Caballeros
Aug 23
STI7:00 amSantiago de los Caballeros
18h 30m
2 stops
SFO10:30 pmSan Francisco
$770

momondo Fare Finder

 
Customize your flight search to find flights from San Francisco to Santiago de los Caballeros that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated July 4, 2026.
Use the filters below to find and compare flights from San Francisco to Santiago de los Caballeros that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

San FranciscoSantiago de los Caballeros

SFO - STI

SFOSTI

San Francisco

Mon 9/28

11:10 pm-1:27 pm

1 stop11h 17m

Santiago de los Caballeros

Thu 10/1

3:49 pm-11:19 pm

1 stop10h 30m

$632

San FranciscoSantiago de los Caballeros

SFO - STI

SFOSTI

San Francisco

Mon 9/28

11:59 pm-8:25 pm

1 stop17h 26m

Santiago de los Caballeros

Thu 10/1

3:49 pm-11:19 pm

1 stop10h 30m

$651

San FranciscoSantiago de los Caballeros

SFO - STI

SFOSTI

San Francisco

Mon 9/28

11:59 pm-8:25 pm

1 stop17h 26m

Santiago de los Caballeros

Thu 10/1

3:49 pm-11:19 pm

1 stop10h 30m

$656

San FranciscoSantiago de los Caballeros

SFO - STI

SFOSTI

San Francisco

Thu 8/13

10:40 pm-7:03 am

1 stop29h 23m

Santiago de los Caballeros

Fri 8/21

8:13 am-11:51 pm

1 stop18h 38m

$663

San FranciscoSantiago de los Caballeros

SFO - STI

SFOSTI

San Francisco

Sun 8/16

10:40 pm-3:01 pm

1 stop13h 21m

Santiago de los Caballeros

Sun 8/23

8:13 am-11:51 pm

1 stop18h 38m

$677

San FranciscoSantiago de los Caballeros

SFO - STI

SFOSTI

San Francisco

Thu 8/13

10:59 am-7:03 am

1 stop17h 04m

Santiago de los Caballeros

Fri 8/21

8:13 am-11:51 pm

1 stop18h 38m

$682

San FranciscoSantiago de los Caballeros

SFO - STI

SFOSTI

San Francisco

Thu 10/22

7:59 am-1:21 am

1 stop14h 22m

Santiago de los Caballeros

Tue 10/27

3:44 pm-11:30 pm

1 stop10h 46m

$684

San FranciscoSantiago de los Caballeros

SFO - STI

SFOSTI

San Francisco

Tue 8/18

10:40 pm-3:01 pm

1 stop13h 21m

Santiago de los Caballeros

Tue 8/25

4:54 pm-11:51 pm

1 stop9h 57m

$705

San FranciscoSantiago de los Caballeros

SFO - STI

SFOSTI

San Francisco

Sat 10/3

10:10 pm-1:21 am

1 stop24h 11m

Santiago de los Caballeros

Sun 10/25

5:01 am-9:48 am

1 stop31h 47m

$715

San FranciscoSantiago de los Caballeros

SFO - STI

SFOSTI

San Francisco

Thu 10/22

10:59 pm-2:12 pm

1 stop12h 13m

Santiago de los Caballeros

Tue 10/27

3:16 pm-11:59 pm

1 stop11h 43m

$720

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 13 resultsSorted by cheapest first
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See travel insights to Santiago de los Caballeros from

How to get the cheapest flight ticket from San Francisco to Santiago de los Caballeros

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between San Francisco and Santiago de los Caballeros?

What is the cheapest month to fly to Santiago de los Caballeros?

The cheapest month to fly to Santiago de los Caballeros from San Francisco is in September. Flight prices, which tend to average around $0, are often lower during this time because this is during the off-season. If you aren’t able to travel to Santiago de los Caballeros during the month of September, then flying in February is also cheap. Prices for this month can be found on momondo for an average of $490.

When to book flights from San Francisco to Santiago de los Caballeros

Are you open to changing your travel dates? Check out the ideal times to fly from San Francisco to Santiago de los Caballeros according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap San Francisco to Santiago de los Caballeros (SFO to STI) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from San Francisco to Santiago de los Caballeros

Fastest flight time

11h 17m

Direct flights

None
The fastest flight from San Francisco to Santiago de los Caballeros takes 11h 17m
There are no direct flights from San Francisco to Santiago de los Caballeros. There are no popular flight routes from San Francisco to Santiago de los Caballeros.
Search flight deals

Frequently asked questions about flying from San Francisco to Santiago de los Caballeros

  • How far is San Francisco to Santiago de los Caballeros by plane?

    A flight from San Francisco to Santiago de los Caballeros will travel around 3331.5 mi. A reasonable flight in good conditions will take 11h 17m.

  • When did momondo last update prices for flights from San Francisco Airport to Santiago de los Caballeros Airport?

    Prices for flights from San Francisco Airport to Santiago de los Caballeros Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from San Francisco Airport to Santiago de los Caballeros Airport?

  • How old do you have to be to fly from San Francisco Airport to Santiago de los Caballeros Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from San Francisco Airport to Santiago de los Caballeros Airport.

  • What documentation or ID do you need to fly to Santiago de los Caballeros Airport?

    The travel and health documents you'll need for your trip to Santiago de los Caballeros Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Santiago de los Caballeros Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from San Francisco to Santiago de los Caballeros?

Best airlines flying from San Francisco to Santiago de los Caballeros

Compare and see reviews for airlines that fly from San Francisco to Santiago de los Caballeros with momondo
Airline
Rating
Free Cancellation
Price
JetBluePriceFrom $325Free CancellationRating
7.1
3,010 reviews
Search JetBlue flights
American AirlinesPriceFrom $617Free CancellationRating
7.1
11,765 reviews
Search American Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from San Francisco to Santiago de los Caballeros?

Finding the right flight to Santiago de los Caballeros from San Francisco is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Santiago de los Caballeros quick and easy, saving you time and money.

Can I find flights from San Francisco to Santiago de los Caballeros with flexible booking policies on momondo?

Flights from San Francisco to Santiago de los Caballeros with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from San Francisco to Santiago de los Caballeros?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from San Francisco to Santiago de los Caballeros.

I’m not ready to book a flight from San Francisco to Santiago de los Caballeros right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of San Francisco to Santiago de los Caballeros flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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