What airlines fly to Santiago?

LATAM Airlines, American Airlines and United Airlines are the top three most popular airlines that fly to Santiago from San Francisco according to our data. LATAM Airlines is the first choice among our users, with 36% of people opting to fly with this airline when traveling to Santiago. Keep in mind that there are 7 different airlines that fly to Santiago on a routine basis, so you have a few additional options to choose from.

Which layover airport has the shortest connection time from San Francisco to Santiago?

Atlanta (ATL) has the shortest average layover time for this route: 1h 53m.

Which layover airport offers the lowest fares from San Francisco to Santiago?

Flights via Houston (IAH) offer the lowest average round-trip price of $668.

Which layover airport has the shortest travel time from San Francisco to Santiago?

Flights connecting via Panama City (PTY) have the shortest average one-way travel time: 14h 43m.

Which airport is the most popular layover for flights between San Francisco and Santiago?

Houston (IAH) was the most common stop: 34% of momondo users choosing 1-stop flights on this route connected there.

When did momondo last update prices for flights from San Francisco Airport to Santiago Arturo Merino Benitez Airport?

Prices for flights from San Francisco Airport to Santiago Arturo Merino Benitez Airport were last updated today.

How many operators does momondo search for flights from San Francisco Airport to Santiago Arturo Merino Benitez Airport?

As of June 2026, there are 7 operators available to choose from for flights from San Francisco Airport to Santiago Arturo Merino Benitez Airport.

How old do you have to be to fly from San Francisco Airport to Santiago Arturo Merino Benitez Airport?

The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from San Francisco Airport to Santiago Arturo Merino Benitez Airport.

What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?

The necessary travel and health documents for your Santiago Arturo Merino Benitez Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

$358 Cheap Flights from San Francisco to Santiago in 2026

Q: What is the typical price of a round-trip flight between San Francisco and Santiago?

Prices are currently low for flights on this route. Typical prices usually range from $953 to $774. The lowest price recently found on this route was $661.

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Find the cheapest flights from San Francisco to Santiago

Round-trip

One-way

Last minute

Cheap round-trip flights

Enter your travel dates to find the best prices.

1:12 am - 3:56 am

SFO

SCL

22h 44m

1 stop

5:07 am - 11:12 pm

SCL

SFO

23h 05m

1 stop

$661Copa Airlines

Sun, Oct 18 - Thu, Nov 5

6:00 am - 7:15 am

SFO

SCL

22h 15m

1 stop

8:40 pm - 2:46 pm

SCL

SFO

22h 06m

1 stop

$673Delta

Tue, Sep 1 - Wed, Sep 30

7:30 am - 7:05 am

SFO

SCL

20h 35m

1 stop

9:30 pm - 1:10 pm

SCL

SFO

19h 40m

2 stops

$678American Airlines

Wed, Sep 2 - Wed, Sep 30

11:35 pm - 1:35 pm

SFO

SCL

34h 00m

2 stops

11:25 pm - 1:25 pm

SCL

SFO

18h 00m

1 stop

$683LATAM Airlines

Mon, Sep 21 - Fri, Sep 25

7:36 pm - 3:38 am

SFO

SCL

27h 02m

1 stop

3:48 am - 11:12 pm

SCL

SFO

24h 24m

1 stop

$684Copa Airlines

Sun, Nov 1 - Fri, Nov 6

11:35 pm - 1:35 pm

SFO

SCL

34h 00m

2 stops

11:00 pm - 3:49 pm

SCL

SFO

20h 49m

2 stops

$688LATAM Airlines

Mon, Sep 21 - Fri, Sep 25

8:55 am - 5:35 am

SFO

SCL

16h 40m

1 stop

7:05 am - 11:11 pm

SCL

SFO

21h 06m

2 stops

$690LATAM Airlines

Sun, Oct 25 - Fri, Nov 6

7:30 am - 6:50 am

SFO

SCL

19h 20m

2 stops

7:05 am - 11:11 pm

SCL

SFO

21h 06m

2 stops

$694LATAM Airlines

Sun, Oct 25 - Fri, Nov 6

6:50 am - 4:50 am

SFO

SCL

18h 00m

2 stops

11:25 pm - 10:53 am

SCL

SFO

15h 28m

1 stop

$704LATAM Airlines

Tue, Sep 15 - Sat, Sep 26

10:10 pm - 1:35 pm

SFO

SCL

35h 25m

2 stops

11:25 pm - 10:53 am

SCL

SFO

15h 28m

1 stop

$705LATAM Airlines

Mon, Sep 21 - Fri, Sep 25

Avianca flights from San Francisco to Santiago

Our best Avianca deals on San Francisco to Santiago flight tickets

Avianca

Aug 7

SFO11:55 pmSan Francisco

25h 50m

2 stops

SCL4:45 amSantiago Arturo Merino Benitez

Aug 18

SCL3:20 pmSantiago Arturo Merino Benitez

34h 15m

2 stops

SFO10:35 pmSan Francisco

$766

Avianca

Jul 6

SFO2:15 pmSan Francisco

35h 30m

2 stops

SCL4:45 amSantiago Arturo Merino Benitez

Aug 4

SCL12:30 amSantiago Arturo Merino Benitez

25h 05m

2 stops

SFO10:35 pmSan Francisco

$776

Avianca

Jun 16

SFO2:30 amSan Francisco

32h 45m

2 stops

SCL2:15 pmSantiago Arturo Merino Benitez

Jun 28

SCL3:20 pmSantiago Arturo Merino Benitez

34h 15m

2 stops

SFO10:35 pmSan Francisco

$986

American Airlines flights from San Francisco to Santiago

Our best American Airlines deals on San Francisco to Santiago flight tickets

American Airlines

Sep 2

SFO7:30 amSan Francisco

20h 35m

1 stop

SCL7:05 amSantiago Arturo Merino Benitez

Sep 30

SCL9:30 pmSantiago Arturo Merino Benitez

19h 40m

2 stops

SFO1:10 pmSan Francisco

$678

American Airlines

Oct 10

SFO9:16 amSan Francisco

18h 34m

2 stops

SCL7:50 amSantiago Arturo Merino Benitez

Oct 27

SCL10:15 pmSantiago Arturo Merino Benitez

24h 24m

2 stops

SFO6:39 pmSan Francisco

$732

American Airlines

Sep 1

SFO10:50 amSan Francisco

16h 35m

1 stop

SCL6:25 amSantiago Arturo Merino Benitez

Sep 30

SCL9:30 pmSantiago Arturo Merino Benitez

16h 48m

1 stop

SFO10:18 amSan Francisco

$739

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

San FranciscoSantiago

SFO - SCL

SFOSCL

San Francisco

Sun 10/18

1:12 am-3:56 am

1 stop22h 44m

Santiago Arturo Merino Benitez

Thu 11/5

5:07 am-11:12 pm

1 stop23h 05m

$661

San FranciscoSantiago

SFO - SCL

SFOSCL

San Francisco

Tue 9/1

6:00 am-7:15 am

1 stop22h 15m

Santiago Arturo Merino Benitez

Wed 9/30

8:40 pm-2:46 pm

1 stop22h 06m

$673

San FranciscoSantiago

SFO - SCL

SFOSCL

San Francisco

Wed 9/2

7:30 am-7:05 am

1 stop20h 35m

Santiago Arturo Merino Benitez

Wed 9/30

9:30 pm-1:10 pm

2 stops19h 40m

$678

San FranciscoSantiago

SFO - SCL

SFOSCL

San Francisco

Mon 9/21

11:35 pm-1:35 pm

2 stops34h 00m

Santiago Arturo Merino Benitez

Fri 9/25

11:25 pm-1:25 pm

1 stop18h 00m

$683

San FranciscoSantiago

SFO - SCL

SFOSCL

San Francisco

Sun 11/1

7:36 pm-3:38 am

1 stop27h 02m

Santiago Arturo Merino Benitez

Fri 11/6

3:48 am-11:12 pm

1 stop24h 24m

$684

San FranciscoSantiago

SFO - SCL

SFOSCL

San Francisco

Mon 9/21

11:35 pm-1:35 pm

2 stops34h 00m

Santiago Arturo Merino Benitez

Fri 9/25

11:00 pm-3:49 pm

2 stops20h 49m

$688

San FranciscoSantiago

SFO - SCL

SFOSCL

San Francisco

Sun 10/25

8:55 am-5:35 am

1 stop16h 40m

Santiago Arturo Merino Benitez

Fri 11/6

7:05 am-11:11 pm

2 stops21h 06m

$690

San FranciscoSantiago

SFO - SCL

SFOSCL

San Francisco

Sun 10/25

7:30 am-6:50 am

2 stops19h 20m

Santiago Arturo Merino Benitez

Fri 11/6

7:05 am-11:11 pm

2 stops21h 06m

$694

Quickest round-trip

San FranciscoSantiago

SFO - SCL

SFOSCL

San Francisco

Tue 9/15

6:50 am-4:50 am

2 stops18h 00m

Santiago Arturo Merino Benitez

Sat 9/26

11:25 pm-10:53 am

1 stop15h 28m

$704

San FranciscoSantiago

SFO - SCL

SFOSCL

San Francisco

Mon 9/21

10:10 pm-1:35 pm

2 stops35h 25m

Santiago Arturo Merino Benitez

Fri 9/25

11:25 pm-10:53 am

1 stop15h 28m

$705

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from San Francisco to Santiago

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Layovers

What is the typical price of a round-trip flight between San Francisco and Santiago?

What is the cheapest month to fly to Santiago?

In general, January is the cheapest month to fly from San Francisco to Santiago. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $666. If you don’t want to visit Santiago in January, then you should wait until October to fly from San Francisco, when ticket prices are also cheap, with an average price of $683.

How far in advance should I book a flight from San Francisco to Santiago?

You are more likely to see cheaper flights to Santiago from San Francisco when booking weeks ahead of your departure date. In general, you can expect to find flights to Santiago for around $827 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Santiago from San Francisco for as low as $646 on momondo.

How have San Francisco to Santiago flight prices changed over time?

As of June 2026, prices for San Francisco to Santiago flights are approximately 6% cheaper when compared to flights at the same time last year.

When to book flights from San Francisco to Santiago

Are you open to changing your travel dates? Check out the ideal times to fly from San Francisco to Santiago according to our flight data. Find out which month and days have the cheapest flights.

Estimated round-trip price

Cheap San Francisco to Santiago (SFO to SCL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from San Francisco to Santiago

Fastest flight time	13h 12m
Direct flights	None

The fastest flight from San Francisco to Santiago takes 13h 12m

There are no direct flights from San Francisco to Santiago. There are no popular flight routes from San Francisco to Santiago.

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Frequently asked questions about flying from San Francisco to Santiago

How far is San Francisco to Santiago Arturo Merino Benitez by plane?
A flight from San Francisco to Santiago Arturo Merino Benitez will travel around 5934.4 mi. In terms of flight time, this usually takes a little over 13h 12m.
When did momondo last update prices for flights from San Francisco Airport to Santiago Arturo Merino Benitez Airport?
Prices for flights from San Francisco Airport to Santiago Arturo Merino Benitez Airport were last updated today.
How many operators does momondo search for flights from San Francisco Airport to Santiago Arturo Merino Benitez Airport?
As of June 2026, there are 7 operators available to choose from for flights from San Francisco Airport to Santiago Arturo Merino Benitez Airport.
How old do you have to be to fly from San Francisco Airport to Santiago Arturo Merino Benitez Airport?
The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from San Francisco Airport to Santiago Arturo Merino Benitez Airport.
What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?
The necessary travel and health documents for your Santiago Arturo Merino Benitez Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.
What is the most popular airline from San Francisco to Santiago?
Based on momondo bookings for this flight route, the most popular airline on flight routes from San Francisco to Santiago is LATAM Airlines (30% of total bookings). The next most popular airlines are United Airlines (19%), American Airlines (19%), and Delta (16%).

Best airlines flying from San Francisco to Santiago

Compare and see reviews for airlines that fly from San Francisco to Santiago with momondo

Airline	Rating	Free Cancellation	Price
Avianca	PriceFrom $290	Free Cancellation	Rating 6.5 2,531 reviews	Search Avianca flights
Copa Airlines	PriceFrom $470	Free Cancellation	Rating 7.5 1,568 reviews	Search Copa Airlines flights
American Airlines	PriceFrom $494	Free Cancellation	Rating 7.1 11,654 reviews	Search American Airlines flights
United Airlines	PriceFrom $494	Free Cancellation	Rating 7.4 9,777 reviews	Search United Airlines flights
Delta	PriceFrom $593	Free Cancellation	Rating 7.8 8,398 reviews	Search Delta flights
LATAM Airlines	PriceFrom $593	Free Cancellation	Rating 7.4 1,921 reviews	Search LATAM Airlines flights
Aeromexico	PriceFrom $782	Free Cancellation	Rating 7.4 1,492 reviews	Search Aeromexico flights

Viña del Mar

Valparaíso

Santa Cruz

Valle Nevado

San Fernando

Pichilemu

Zapallar

Why use momondo?

Why should I use momondo to find a flight deal from San Francisco to Santiago?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Santiago from San Francisco.

Can I find flights from San Francisco to Santiago with flexible booking policies on momondo?

Flights from San Francisco to Santiago with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from San Francisco to Santiago?

Once all potential San Francisco to Santiago flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from San Francisco to Santiago right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Santiago from San Francisco. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.