Latest deals
Insights
When to book
FAQs
Reviews
Price Alerts

Cheap flights from San Francisco to Santiago from $305

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from San Francisco to Santiago departing on 12/29. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

Discover deals from 900+ travel sites with momondo.

Save money when you book flights with momondo

Big names and deals

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Price Alerts

Not ready to book? to track prices.
Search flight deals

Find the cheapest flights from San Francisco to Santiago

Cheap round-trip flights

Enter your travel dates to find the best prices.
United Airlines Logo
5:00 am - 8:50 am
SFO
-
SCL
22h 50m1 stop
United Airlines Logo
10:45 pm - 7:00 pm
SCL
-
SFO
25h 15m1 stop
$494United Airlines
lun., ene. 12 - mar., feb. 3
American Airlines Logo
11:15 am - 9:00 am
SFO
-
SCL
16h 45m2 stops
American Airlines Logo
10:35 pm - 11:03 am
SCL
-
SFO
17h 28m1 stop
$499American Airlines
lun., ene. 19 - lun., feb. 9
Copa Airlines Logo
1:54 am - 12:34 am
SFO
-
SCL
18h 40m1 stop
Copa Airlines Logo
12:28 pm - 11:40 pm
SCL
-
SFO
15h 12m1 stop
$502Copa Airlines
mié., mar. 18 - mar., mar. 24
United Airlines Logo
4:10 pm - 8:50 am
SFO
-
SCL
35h 40m1 stop
United Airlines Logo
10:45 pm - 4:50 pm
SCL
-
SFO
23h 05m1 stop
$503United Airlines
dom., ene. 18 - jue., ene. 29
United Airlines Logo
5:00 am - 8:50 am
SFO
-
SCL
22h 50m1 stop
United Airlines Logo
10:45 pm - 5:50 pm
SCL
-
SFO
24h 05m1 stop
$504United Airlines
mar., ene. 13 - dom., feb. 1
United Airlines Logo
7:10 pm - 8:50 am
SFO
-
SCL
32h 40m1 stop
United Airlines Logo
10:45 pm - 12:20 pm
SCL
-
SFO
18h 35m1 stop
$513United Airlines
jue., ene. 15 - jue., ene. 29
United Airlines Logo
7:02 am - 8:50 am
SFO
-
SCL
20h 48m1 stop
United Airlines Logo
10:45 pm - 5:54 pm
SCL
-
SFO
24h 09m1 stop
$514United Airlines
dom., ene. 4 - mié., feb. 18
Copa Airlines Logo
1:23 am - 11:26 pm
SFO
-
SCL
19h 03m1 stop
Copa Airlines Logo
2:22 am - 11:40 pm
SCL
-
SFO
24h 18m1 stop
$522Copa Airlines
dom., abr. 19 - dom., may. 3
United Airlines Logo
11:59 pm - 8:50 am
SFO
-
SCL
27h 51m1 stop
United Airlines Logo
10:45 pm - 2:57 pm
SCL
-
SFO
21h 12m1 stop
$523United Airlines
sáb., ene. 3 - jue., feb. 19
United Airlines Logo
11:59 pm - 8:50 am
SFO
-
SCL
27h 51m1 stop
United Airlines Logo
10:45 pm - 7:31 am
SCL
-
SFO
37h 46m1 stop
$532United Airlines
sáb., ene. 3 - dom., feb. 15

American Airlines flights from San Francisco to Santiago

Our best American Airlines deals on San Francisco to Santiago flight tickets
American Airlines
Jan 19
SFO11:15 amSan Francisco
16h 45m
2 stops
SCL9:00 amSantiago Arturo Merino Benitez
Feb 9
SCL10:35 pmSantiago Arturo Merino Benitez
19h 05m
2 stops
SFO12:40 pmSan Francisco
$499
Find similar
American Airlines
Dec 7
SFO9:00 amSan Francisco
18h 10m
2 stops
SCL8:10 amSantiago Arturo Merino Benitez
Dec 11
SCL10:30 pmSantiago Arturo Merino Benitez
17h 36m
1 stop
SFO11:06 amSan Francisco
$519
Find similar
American Airlines
Jan 16
SFO7:00 amSan Francisco
20h 15m
1 stop
SCL8:15 amSantiago Arturo Merino Benitez
Jan 26
SCL10:30 pmSantiago Arturo Merino Benitez
20h 16m
1 stop
SFO1:46 pmSan Francisco
$534
Find similar

LATAM Airlines flights from San Francisco to Santiago

Our best LATAM Airlines deals on San Francisco to Santiago flight tickets
LATAM Airlines
Mar 19
SFO6:00 amSan Francisco
19h 35m
2 stops
SCL5:35 amSantiago Arturo Merino Benitez
Mar 24
SCL11:55 pmSantiago Arturo Merino Benitez
19h 08m
1 stop
SFO3:03 pmSan Francisco
$575
Find similar
LATAM Airlines
Apr 20
SFO6:00 amSan Francisco
22h 00m
1 stop
SCL7:00 amSantiago Arturo Merino Benitez
May 4
SCL11:00 pmSantiago Arturo Merino Benitez
21h 10m
2 stops
SFO5:10 pmSan Francisco
$587
Find similar
LATAM Airlines
Apr 20
SFO7:30 amSan Francisco
20h 25m
2 stops
SCL6:55 amSantiago Arturo Merino Benitez
May 4
SCL11:00 pmSantiago Arturo Merino Benitez
21h 10m
2 stops
SFO5:10 pmSan Francisco
$592
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from San Francisco to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated diciembre 4, 2025.
Use the filters below to find and compare flights from San Francisco to Santiago that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

San FranciscoSantiago

SFO - SCL

SFOSCL

San Francisco

lun. 1/12

5:00 am-8:50 am

1 stop22h 50m

Santiago Arturo Merino Benitez

mar. 2/3

10:45 pm-7:00 pm

1 stop25h 15m

$494

San FranciscoSantiago

SFO - SCL

SFOSCL

San Francisco

lun. 1/19

11:15 am-9:00 am

2 stops16h 45m

Santiago Arturo Merino Benitez

lun. 2/9

10:35 pm-11:03 am

1 stop17h 28m

$499

San FranciscoSantiago

SFO - SCL

SFOSCL

San Francisco

mié. 3/18

1:54 am-12:34 am

1 stop18h 40m

Santiago Arturo Merino Benitez

mar. 3/24

12:28 pm-11:40 pm

1 stop15h 12m

$502

San FranciscoSantiago

SFO - SCL

SFOSCL

San Francisco

dom. 1/18

4:10 pm-8:50 am

1 stop35h 40m

Santiago Arturo Merino Benitez

jue. 1/29

10:45 pm-4:50 pm

1 stop23h 05m

$503

San FranciscoSantiago

SFO - SCL

SFOSCL

San Francisco

mar. 1/13

5:00 am-8:50 am

1 stop22h 50m

Santiago Arturo Merino Benitez

dom. 2/1

10:45 pm-5:50 pm

1 stop24h 05m

$504

San FranciscoSantiago

SFO - SCL

SFOSCL

San Francisco

jue. 1/15

7:10 pm-8:50 am

1 stop32h 40m

Santiago Arturo Merino Benitez

jue. 1/29

10:45 pm-12:20 pm

1 stop18h 35m

$513

San FranciscoSantiago

SFO - SCL

SFOSCL

San Francisco

dom. 1/4

7:02 am-8:50 am

1 stop20h 48m

Santiago Arturo Merino Benitez

mié. 2/18

10:45 pm-5:54 pm

1 stop24h 09m

$514

San FranciscoSantiago

SFO - SCL

SFOSCL

San Francisco

dom. 4/19

1:23 am-11:26 pm

1 stop19h 03m

Santiago Arturo Merino Benitez

dom. 5/3

2:22 am-11:40 pm

1 stop24h 18m

$522

San FranciscoSantiago

SFO - SCL

SFOSCL

San Francisco

sáb. 1/3

11:59 pm-8:50 am

1 stop27h 51m

Santiago Arturo Merino Benitez

jue. 2/19

10:45 pm-2:57 pm

1 stop21h 12m

$523

San FranciscoSantiago

SFO - SCL

SFOSCL

San Francisco

sáb. 1/3

11:59 pm-8:50 am

1 stop27h 51m

Santiago Arturo Merino Benitez

dom. 2/15

10:45 pm-7:31 am

1 stop37h 46m

$532

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
1
2

See travel insights to Santiago from

How to get the cheapest flight ticket from San Francisco to Santiago

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Santiago?

In general, October is the cheapest month to fly from San Francisco to Santiago. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $683. If you don’t want to visit Santiago in October, then you should wait until May to fly from San Francisco, when ticket prices are also cheap, with an average price of $708.

What is the cheapest day to depart on your flight to Santiago?

The cheapest day to depart on your flight to Santiago is on a Wednesday when prices can be found for as low as $812. This is often the case because there is less demand to fly during this day of the week. Be sure to avoid booking your departure on a Saturday as prices are generally higher than usual. According to our data, the average ticket price to Santiago on Saturday is $1,066.

What is the cheapest time of day to depart on your flight to Santiago?

In the evening is the cheapest time of day to fly from San Francisco to Santiago when you can find flight prices for as low as $831. Flying to Santiago in the evening is an ideal time because this is during off-peak travel hours. At noon is when there is more demand to fly to Santiago, so prices are often more expensive at around $1,007 per ticket.

How far in advance should I book a flight to Santiago?

You are more likely to see cheaper flights to Santiago from San Francisco when booking weeks ahead of your departure date. In general, you can expect to find flights to Santiago for around $791 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Santiago from San Francisco for as low as $651 on momondo.

Can stopping save me money on San Francisco to Santiago flights?

You could potentially save up to 3% on your flight if you consider stops on a San Francisco to Santiago flight.

How have San Francisco to Santiago flight prices changed over time?

As of December 2025, prices for San Francisco to Santiago flights are approximately 2% cheaper when compared to flights at the same time last year.

When to book flights from San Francisco to Santiago

Are you open to changing your travel dates? Check out the ideal times to fly from San Francisco to Santiago according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap San Francisco to Santiago (SFO to SCL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from San Francisco to Santiago

Fastest flight time

17h 45m

Direct flights

None
The fastest flight from San Francisco to Santiago takes 17h 45m
There are no direct flights from San Francisco to Santiago. There are no popular flight routes from San Francisco to Santiago.
Search flight deals

  • How far is San Francisco to Santiago Arturo Merino Benitez by plane?

    A flight from San Francisco to Santiago Arturo Merino Benitez will travel around 5935.3 mi. In terms of flight time, this usually takes a little over 13h 33m.

  • When did momondo last update prices for flights from San Francisco Airport to Santiago Arturo Merino Benitez Airport?

    Prices for flights from San Francisco Airport to Santiago Arturo Merino Benitez Airport were last updated today.

  • How many operators does momondo search for flights from San Francisco Airport to Santiago Arturo Merino Benitez Airport?

  • How old do you have to be to fly from San Francisco Airport to Santiago Arturo Merino Benitez Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from San Francisco Airport to Santiago Arturo Merino Benitez Airport.

  • What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?

    The necessary travel and health documents for your Santiago Arturo Merino Benitez Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from San Francisco to Santiago?

Best airlines flying from San Francisco to Santiago

Compare and see reviews for airlines that fly from San Francisco to Santiago with momondo
Airline
Rating
Free Cancellation
Price
AviancaPriceFrom $492Free CancellationRating
6.6
2,476 reviews
Search Avianca flights
United AirlinesPriceFrom $494Free CancellationRating
7.4
9,063 reviews
Search United Airlines flights
American AirlinesPriceFrom $498Free CancellationRating
7.2
11,045 reviews
Search American Airlines flights
Copa AirlinesPriceFrom $592Free CancellationRating
7.6
1,558 reviews
Search Copa Airlines flights
DeltaPriceFrom $594Free CancellationRating
7.9
8,011 reviews
Search Delta flights
LATAM AirlinesPriceFrom $594Free CancellationRating
7.5
1,889 reviews
Search LATAM Airlines flights
AeromexicoPriceFrom $758Free CancellationRating
7.4
1,653 reviews
Search Aeromexico flights

Traveling to a place near Santiago?

Book flights to Santiago if you plan to visit one of these locations
Viña del Mar
Santa Cruz
Valparaíso
Valle Nevado
San Fernando
Pichilemu

Why use momondo?

Why should I use momondo to find a flight deal from San Francisco to Santiago?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Santiago from San Francisco.

Can I find flights from San Francisco to Santiago with flexible booking policies on momondo?

Flights from San Francisco to Santiago with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from San Francisco to Santiago?

Once all potential San Francisco to Santiago flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from San Francisco to Santiago right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Santiago from San Francisco. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

An easier way to manage your Santiago trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
Start using Trips
Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.
1 adult
sáb. 1/3
sáb. 1/10
By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to Chile