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Cheap flights from San Francisco to Santiago from $310

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from San Francisco to Santiago departing on 5/12. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from San Francisco to Santiago

Cheap round-trip flights

These are some of the best round-trip flight deals from San Francisco to Santiago that have been recently found on momondo from popular airlines, departing in the coming months.
Avianca Logo
2:30 am - 10:30 pmSFO-SCL
17h 00m2 stops
Avianca Logo
2:30 pm - 12:35 pmSCL-SFO
25h 05m2 stops
$602Avianca
Find Deal
Tue, May 27 - Wed, Jun 4
Avianca Logo
12:05 am - 12:50 amSFO-SCL
21h 45m3 stops
Avianca Logo
2:30 pm - 12:35 pmSCL-SFO
25h 05m2 stops
$604Avianca
Find Deal
Sat, May 31 - Mon, Jun 9
LATAM Airlines Logo
11:05 am - 6:00 amSFO-SCL
15h 55m1 stop
LATAM Airlines Logo
10:45 pm - 9:57 amSCL-SFO
14h 12m1 stop
$637LATAM Airlines
Find Deal
Tue, Aug 19 - Tue, Aug 26
LATAM Airlines Logo
10:55 am - 6:00 amSFO-SCL
16h 05m1 stop
LATAM Airlines Logo
8:40 pm - 10:12 amSCL-SFO
16h 32m1 stop
$642LATAM Airlines
Find Deal
Tue, Jun 17 - Mon, Jul 14
Copa Airlines Logo
1:37 am - 11:08 pmSFO-SCL
18h 31m1 stop
Copa Airlines Logo
4:11 am - 11:40 pmSCL-SFO
22h 29m1 stop
$652Copa Airlines
Find Deal
Tue, May 27 - Wed, Jun 4
Delta Logo
1:00 pm - 7:10 pmSFO-SCL
27h 10m2 stops
Delta Logo
8:20 am - 11:13 pmSCL-SFO
18h 53m2 stops
$664Delta
Find Deal
Mon, Aug 25 - Tue, Sep 9
Copa Airlines Logo
1:37 am - 11:08 pmSFO-SCL
18h 31m1 stop
Copa Airlines Logo
4:11 am - 11:40 pmSCL-SFO
22h 29m1 stop
$678Copa Airlines
Find Deal
Sun, Jun 22 - Thu, Jun 26
Delta Logo
1:00 pm - 6:00 amSFO-SCL
14h 00m1 stop
Delta Logo
8:20 am - 11:13 pmSCL-SFO
18h 53m2 stops
$689Delta
Find Deal
Fri, Aug 22 - Tue, Sep 9
American Airlines Logo
7:00 am - 7:00 amSFO-SCL
21h 00m2 stops
American Airlines Logo
9:55 pm - 7:00 pmSCL-SFO
24h 05m1 stop
$819American Airlines
Find Deal
Wed, Jun 11 - Wed, Jun 18
American Airlines Logo
7:20 am - 6:55 amSFO-SCL
20h 35m2 stops
American Airlines Logo
9:00 pm - 10:52 amSCL-SFO
16h 52m1 stop
$858American Airlines
Find Deal
Fri, May 9 - Sun, May 25

Avianca flights from San Francisco to Santiago

Our best Avianca deals on San Francisco to Santiago flight tickets
Avianca
May 27
SFO2:30 amSan Francisco
17h 00m
2 stops
SCL10:30 pmSantiago Arturo Merino Benitez
Jun 4
SCL2:30 pmSantiago Arturo Merino Benitez
25h 05m
2 stops
SFO12:35 pmSan Francisco
Avianca
May 31
SFO12:05 amSan Francisco
21h 45m
3 stops
SCL12:50 amSantiago Arturo Merino Benitez
Jun 9
SCL2:30 pmSantiago Arturo Merino Benitez
25h 05m
2 stops
SFO12:35 pmSan Francisco
Avianca
May 15
SFO2:30 amSan Francisco
17h 00m
2 stops
SCL10:30 pmSantiago Arturo Merino Benitez
May 23
SCL2:30 pmSantiago Arturo Merino Benitez
36h 25m
2 stops
SFO11:55 pmSan Francisco

LATAM Airlines flights from San Francisco to Santiago

Our best LATAM Airlines deals on San Francisco to Santiago flight tickets
LATAM Airlines
Aug 19
SFO11:05 amSan Francisco
15h 55m
1 stop
SCL6:00 amSantiago Arturo Merino Benitez
Aug 26
SCL10:45 pmSantiago Arturo Merino Benitez
14h 12m
1 stop
SFO9:57 amSan Francisco
LATAM Airlines
Jun 17
SFO10:55 amSan Francisco
16h 05m
1 stop
SCL6:00 amSantiago Arturo Merino Benitez
Jul 14
SCL8:40 pmSantiago Arturo Merino Benitez
16h 32m
1 stop
SFO10:12 amSan Francisco
LATAM Airlines
Aug 19
SFO6:00 amSan Francisco
18h 30m
2 stops
SCL3:30 amSantiago Arturo Merino Benitez
Aug 26
SCL10:45 pmSantiago Arturo Merino Benitez
16h 13m
1 stop
SFO11:58 amSan Francisco

See travel insights to Santiago from

How to get the cheapest flight ticket from San Francisco to Santiago

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between San Francisco and Santiago?

What is the cheapest month to fly to Santiago?

In general, May is the cheapest month to fly from San Francisco to Santiago. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $732. If you don’t want to visit Santiago in May, then you should wait until August to fly from San Francisco, when ticket prices are also cheap, with an average price of $785.

What is the cheapest day to depart on your flight to Santiago?

The cheapest day to depart on your flight to Santiago is on a Wednesday when prices can be found for as low as $812. This is often the case because there is less demand to fly during this day of the week. Be sure to avoid booking your departure on a Saturday as prices are generally higher than usual. According to our data, the average ticket price to Santiago on Saturday is $1,066.

What is the cheapest time of day to depart on your flight to Santiago?

In the evening is the cheapest time of day to fly from San Francisco to Santiago when you can find flight prices for as low as $831. Flying to Santiago in the evening is an ideal time because this is during off-peak travel hours. At noon is when there is more demand to fly to Santiago, so prices are often more expensive at around $1,007 per ticket.

How far in advance should I book a flight to Santiago?

You are more likely to see cheaper flights to Santiago from San Francisco when booking 8 weeks ahead of your departure date. In general, you can expect to find flights to Santiago for around $869 when searching 8 weeks out.However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Santiago from San Francisco for as low as $793 on momondo.

How have San Francisco to Santiago flight prices changed over time?

As of April 2025, prices for San Francisco to Santiago flights are approximately 4% more expensive when compared to flights at the same time last year.

When to book flights from San Francisco to Santiago

Are you open to changing your travel dates? Check out the ideal times to fly from San Francisco to Santiago according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap San Francisco to Santiago (SFO to SCL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from San Francisco to Santiago

Best Price Found

$310

Fastest flight time

14h 00m

Direct flights

None

Airports in Santiago

1 airport
The best one-way flight to Santiago from San Francisco in the past 72 hours is $310. The best round-trip flight deal from San Francisco to Santiago found on momondo in the last 72 hours is $602.
The fastest flight from San Francisco to Santiago takes 14h 00m
There are no direct flights from San Francisco to Santiago. Popular non-direct route for this connection is San Francisco Airport - Santiago Arturo Merino Benitez Airport.
There is 1 airport near Santiago: Santiago Arturo Merino Benitez (SCL)

  • How far is San Francisco to Santiago Arturo Merino Benitez by plane?

    A flight from San Francisco to Santiago Arturo Merino Benitez will travel around 5935.3 mi. In terms of flight time, this usually takes a little over 14h 00m.

  • When did momondo last update prices for flights from San Francisco Airport to Santiago Arturo Merino Benitez Airport?

    Prices for flights from San Francisco Airport to Santiago Arturo Merino Benitez Airport were last updated today.

  • How many operators does momondo search for flights from San Francisco Airport to Santiago Arturo Merino Benitez Airport?

  • How old do you have to be to fly from San Francisco Airport to Santiago Arturo Merino Benitez Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from San Francisco Airport to Santiago Arturo Merino Benitez Airport.

  • What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?

    The necessary travel and health documents for your Santiago Arturo Merino Benitez Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from San Francisco to Santiago?


Best airlines flying from San Francisco to Santiago

Compare and see reviews for airlines that fly from San Francisco to Santiago with momondo
Airline
Rating
Free Cancellation
Price
AviancaPriceFrom $473Free CancellationRating
6.7
2,317 reviews
Search Avianca flights
Copa AirlinesPriceFrom $534Free CancellationRating
7.5
1,411 reviews
Search Copa Airlines flights
United AirlinesPriceFrom $622Free CancellationRating
7.4
8,696 reviews
Search United Airlines flights
DeltaPriceFrom $642Free CancellationRating
8.0
7,936 reviews
Search Delta flights
American AirlinesPriceFrom $658Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights
LATAM AirlinesPriceFrom $660Free CancellationRating
7.5
1,767 reviews
Search LATAM Airlines flights
AeromexicoPriceFrom $765Free CancellationRating
7.5
1,698 reviews
Search Aeromexico flights

Traveling to a place near Santiago?

Book flights to Santiago if you plan to visit one of these locations
Viña del Mar
Valparaíso
Santa Cruz
San Fernando
Valle Nevado
Pichilemu

Why use momondo?

Why should I use momondo to find a flight deal from San Francisco to Santiago?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Santiago from San Francisco.

Can I find flights from San Francisco to Santiago with flexible booking policies on momondo?

Flights from San Francisco to Santiago with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from San Francisco to Santiago?

Once all potential San Francisco to Santiago flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from San Francisco to Santiago right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Santiago from San Francisco. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.


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