Latest deals
Insights
When to book
FAQs
Reviews
Price Alerts

Cheap flights from San Francisco to Santiago from $262

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from San Francisco to Santiago departing on 12/3. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

Discover deals from 900+ travel sites with momondo.

Save money when you book flights with momondo

Big names and deals

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Price Alerts

Not ready to book? to track prices.
Search flight deals

Find the cheapest flights from San Francisco to Santiago

Cheap round-trip flights

Enter your travel dates to find the best prices.
United Airlines Logo
1:00 pm - 8:50 amSFO-SCL
14h 50m1 stop
United Airlines Logo
10:45 pm - 4:46 pmSCL-SFO
23h 01m1 stop
$526United Airlines
Find Deal
Wed, Nov 19 - Fri, Dec 5
United Airlines Logo
1:00 pm - 8:50 amSFO-SCL
14h 50m1 stop
United Airlines Logo
10:45 pm - 7:26 pmSCL-SFO
25h 41m1 stop
$527United Airlines
Find Deal
Wed, Nov 19 - Fri, Dec 5
American Airlines Logo
8:20 am - 7:45 amSFO-SCL
18h 25m2 stops
American Airlines Logo
10:30 pm - 1:14 pmSCL-SFO
19h 44m2 stops
$539American Airlines
Find Deal
Wed, Dec 3 - Sat, Dec 13
Copa Airlines Logo
1:54 am - 3:58 amSFO-SCL
22h 04m1 stop
Copa Airlines Logo
12:16 am - 6:25 pmSCL-SFO
21h 09m1 stop
$542Copa Airlines
Find Deal
Tue, Mar 24 - Tue, Apr 7
American Airlines Logo
7:00 am - 8:15 amSFO-SCL
20h 15m2 stops
American Airlines Logo
10:35 pm - 1:50 pmSCL-SFO
20h 15m2 stops
$549American Airlines
Find Deal
Mon, Jan 12 - Tue, Feb 3
LATAM Airlines Logo
11:02 am - 5:35 amSFO-SCL
13h 33m1 stop
LATAM Airlines Logo
6:40 am - 11:16 pmSCL-SFO
21h 36m2 stops
$558LATAM Airlines
Find Deal
Wed, Feb 4 - Wed, Feb 18
Copa Airlines Logo
1:37 am - 8:20 pmSFO-SCL
14h 43m1 stop
Copa Airlines Logo
4:20 am - 6:25 pmSCL-SFO
17h 05m1 stop
$562Copa Airlines
Find Deal
Tue, Mar 31 - Thu, Apr 9
LATAM Airlines Logo
11:40 am - 7:40 amSFO-SCL
15h 00m1 stop
LATAM Airlines Logo
6:40 am - 11:16 pmSCL-SFO
21h 36m2 stops
$570LATAM Airlines
Find Deal
Tue, Jan 27 - Wed, Feb 4
Delta Logo
8:00 am - 7:40 amSFO-SCL
18h 40m1 stop
Delta Logo
11:10 pm - 7:45 pmSCL-SFO
25h 35m1 stop
$594Delta
Find Deal
Sun, Jan 11 - Wed, Jan 21
Delta Logo
7:00 am - 7:40 amSFO-SCL
19h 40m2 stops
Delta Logo
6:30 pm - 10:30 amSCL-SFO
21h 00m2 stops
$599Delta
Find Deal
Fri, Jan 9 - Mon, Feb 2

United Airlines flights from San Francisco to Santiago

Our best United Airlines deals on San Francisco to Santiago flight tickets
United Airlines
Nov 19
SFO1:00 pmSan Francisco
14h 50m
1 stop
SCL8:50 amSantiago Arturo Merino Benitez
Dec 5
SCL10:45 pmSantiago Arturo Merino Benitez
23h 01m
1 stop
SFO4:46 pmSan Francisco
$526
Find similar
United Airlines
Nov 19
SFO1:00 pmSan Francisco
14h 50m
1 stop
SCL8:50 amSantiago Arturo Merino Benitez
Dec 5
SCL10:45 pmSantiago Arturo Merino Benitez
25h 41m
1 stop
SFO7:26 pmSan Francisco
$527
Find similar
United Airlines
Feb 9
SFO5:00 amSan Francisco
22h 50m
1 stop
SCL8:50 amSantiago Arturo Merino Benitez
Feb 17
SCL10:45 pmSantiago Arturo Merino Benitez
24h 09m
1 stop
SFO5:54 pmSan Francisco
$530
Find similar

Copa Airlines flights from San Francisco to Santiago

Our best Copa Airlines deals on San Francisco to Santiago flight tickets
Copa Airlines
Mar 24
SFO1:54 amSan Francisco
22h 04m
1 stop
SCL3:58 amSantiago Arturo Merino Benitez
Apr 7
SCL12:16 amSantiago Arturo Merino Benitez
21h 09m
1 stop
SFO6:25 pmSan Francisco
$542
Find similar
Copa Airlines
Nov 12
SFO12:36 amSan Francisco
18h 30m
1 stop
SCL12:06 amSantiago Arturo Merino Benitez
Nov 17
SCL3:23 amSantiago Arturo Merino Benitez
24h 54m
1 stop
SFO11:17 pmSan Francisco
$557
Find similar
Copa Airlines
Mar 31
SFO1:37 amSan Francisco
14h 43m
1 stop
SCL8:20 pmSantiago Arturo Merino Benitez
Apr 9
SCL4:20 amSantiago Arturo Merino Benitez
17h 05m
1 stop
SFO6:25 pmSan Francisco
$562
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from San Francisco to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated November 5, 2025.
Use the filters below to find and compare flights from San Francisco to Santiago that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

San FranciscoSantiago

SFO - SCL

SFOSCL

San Francisco

Wed 11/19

1:00 pm-8:50 am

1 stop14h 50m

Santiago Arturo Merino Benitez

Fri 12/5

10:45 pm-4:46 pm

1 stop23h 01m

$526

San FranciscoSantiago

SFO - SCL

SFOSCL

San Francisco

Wed 11/19

1:00 pm-8:50 am

1 stop14h 50m

Santiago Arturo Merino Benitez

Fri 12/5

10:45 pm-7:26 pm

1 stop25h 41m

$527

San FranciscoSantiago

SFO - SCL

SFOSCL

San Francisco

Wed 12/3

8:20 am-7:45 am

2 stops18h 25m

Santiago Arturo Merino Benitez

Sat 12/13

10:30 pm-1:14 pm

2 stops19h 44m

$539

San FranciscoSantiago

SFO - SCL

SFOSCL

San Francisco

Tue 3/24

1:54 am-3:58 am

1 stop22h 04m

Santiago Arturo Merino Benitez

Tue 4/7

12:16 am-6:25 pm

1 stop21h 09m

$542

San FranciscoSantiago

SFO - SCL

SFOSCL

San Francisco

Mon 1/12

7:00 am-8:15 am

2 stops20h 15m

Santiago Arturo Merino Benitez

Tue 2/3

10:35 pm-1:50 pm

2 stops20h 15m

$549

San FranciscoSantiago

SFO - SCL

SFOSCL

San Francisco

Wed 2/4

11:02 am-5:35 am

1 stop13h 33m

Santiago Arturo Merino Benitez

Wed 2/18

6:40 am-11:16 pm

2 stops21h 36m

$558

San FranciscoSantiago

SFO - SCL

SFOSCL

San Francisco

Tue 3/31

1:37 am-8:20 pm

1 stop14h 43m

Santiago Arturo Merino Benitez

Thu 4/9

4:20 am-6:25 pm

1 stop17h 05m

$562

San FranciscoSantiago

SFO - SCL

SFOSCL

San Francisco

Tue 1/27

11:40 am-7:40 am

1 stop15h 00m

Santiago Arturo Merino Benitez

Wed 2/4

6:40 am-11:16 pm

2 stops21h 36m

$570

San FranciscoSantiago

SFO - SCL

SFOSCL

San Francisco

Sun 1/11

8:00 am-7:40 am

1 stop18h 40m

Santiago Arturo Merino Benitez

Wed 1/21

11:10 pm-7:45 pm

1 stop25h 35m

$594

San FranciscoSantiago

SFO - SCL

SFOSCL

San Francisco

Fri 1/9

7:00 am-7:40 am

2 stops19h 40m

Santiago Arturo Merino Benitez

Mon 2/2

6:30 pm-10:30 am

2 stops21h 00m

$599

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
1
2

See travel insights to Santiago from

How to get the cheapest flight ticket from San Francisco to Santiago

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Santiago?

In general, October is the cheapest month to fly from San Francisco to Santiago. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $683. If you don’t want to visit Santiago in October, then you should wait until May to fly from San Francisco, when ticket prices are also cheap, with an average price of $708.

What is the cheapest day to depart on your flight to Santiago?

The cheapest day to depart on your flight to Santiago is on a Wednesday when prices can be found for as low as $812. This is often the case because there is less demand to fly during this day of the week. Be sure to avoid booking your departure on a Saturday as prices are generally higher than usual. According to our data, the average ticket price to Santiago on Saturday is $1,066.

What is the cheapest time of day to depart on your flight to Santiago?

In the evening is the cheapest time of day to fly from San Francisco to Santiago when you can find flight prices for as low as $831. Flying to Santiago in the evening is an ideal time because this is during off-peak travel hours. At noon is when there is more demand to fly to Santiago, so prices are often more expensive at around $1,007 per ticket.

How far in advance should I book a flight to Santiago?

You are more likely to see cheaper flights to Santiago from San Francisco when booking weeks ahead of your departure date. In general, you can expect to find flights to Santiago for around $807 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Santiago from San Francisco for as low as $651 on momondo.

Can stopping save me money on San Francisco to Santiago flights?

You could potentially save up to 18% on your flight if you consider stops on a San Francisco to Santiago flight.

How have San Francisco to Santiago flight prices changed over time?

As of November 2025, prices for San Francisco to Santiago flights are approximately 3% cheaper when compared to flights at the same time last year.

When to book flights from San Francisco to Santiago

Are you open to changing your travel dates? Check out the ideal times to fly from San Francisco to Santiago according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap San Francisco to Santiago (SFO to SCL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from San Francisco to Santiago

Direct flights

None
There are no direct flights from San Francisco to Santiago. There are no popular flight routes from San Francisco to Santiago.
Search flight deals

  • How far is San Francisco to Santiago Arturo Merino Benitez by plane?

    A flight from San Francisco to Santiago Arturo Merino Benitez will travel around 5935.3 mi. In terms of flight time, this usually takes a little over 13h 33m.

  • When did momondo last update prices for flights from San Francisco Airport to Santiago Arturo Merino Benitez Airport?

    Prices for flights from San Francisco Airport to Santiago Arturo Merino Benitez Airport were last updated today.

  • How many operators does momondo search for flights from San Francisco Airport to Santiago Arturo Merino Benitez Airport?

  • How old do you have to be to fly from San Francisco Airport to Santiago Arturo Merino Benitez Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from San Francisco Airport to Santiago Arturo Merino Benitez Airport.

  • What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?

    The necessary travel and health documents for your Santiago Arturo Merino Benitez Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from San Francisco to Santiago?

Best airlines flying from San Francisco to Santiago

Compare and see reviews for airlines that fly from San Francisco to Santiago with momondo
Airline
Rating
Free Cancellation
Price
AviancaPriceFrom $492Free CancellationRating
6.6
2,469 reviews
Search Avianca flights
Copa AirlinesPriceFrom $510Free CancellationRating
7.6
1,561 reviews
Search Copa Airlines flights
United AirlinesPriceFrom $534Free CancellationRating
7.4
9,004 reviews
Search United Airlines flights
American AirlinesPriceFrom $542Free CancellationRating
7.2
11,042 reviews
Search American Airlines flights
DeltaPriceFrom $594Free CancellationRating
7.9
8,004 reviews
Search Delta flights
LATAM AirlinesPriceFrom $617Free CancellationRating
7.5
1,874 reviews
Search LATAM Airlines flights
AeromexicoPriceFrom $758Free CancellationRating
7.4
1,673 reviews
Search Aeromexico flights

Traveling to a place near Santiago?

Book flights to Santiago if you plan to visit one of these locations
Viña del Mar
Santa Cruz
Valparaíso
Valle Nevado
San Fernando
Pichilemu

Why use momondo?

Why should I use momondo to find a flight deal from San Francisco to Santiago?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Santiago from San Francisco.

Can I find flights from San Francisco to Santiago with flexible booking policies on momondo?

Flights from San Francisco to Santiago with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from San Francisco to Santiago?

Once all potential San Francisco to Santiago flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from San Francisco to Santiago right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Santiago from San Francisco. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

An easier way to manage your Santiago trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
Start using Trips
Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.
1 adult
Fri 12/5
Fri 12/12
By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to Chile