Cheap flights from San Francisco to Prague from $359

In general, November is the cheapest month to fly from San Francisco to Prague. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $545. If you are unable to visit Prague during the month of November, then departing from San Francisco during the month February is also very affordable. Most momondo users find prices during this month for around $566.

You are more likely to see cheaper flights to Prague from San Francisco when booking weeks ahead of your departure date. In general, you can expect to find flights to Prague for around $724 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Prague from San Francisco for as low as $534 on momondo.

You could potentially save up to 3% on your flight if you consider stops on a San Francisco to Prague flight.

As of April 2026, prices for San Francisco to Prague flights are approximately 10% more expensive when compared to flights at the same time last year.

United Airlines is the most popular carrier operating from San Francisco to Václav Havel Prague

Scandinavian Airlines, Condor and United Airlines are the top three most popular airlines that fly to Prague from San Francisco according to our data. Scandinavian Airlines is the first choice among our users, with 46% of people opting to fly with this airline when traveling to Prague. Keep in mind that there are 11 different airlines that fly to Prague on a routine basis, so you have a few additional options to choose from.

Frankfurt am Main (FRA) was the most common stop: 53% of momondo users choosing 1-stop flights on this route connected there.

Flights via Paris (CDG) offer the lowest average round-trip price of $809.

Flights connecting via Frankfurt am Main (FRA) have the shortest average one-way travel time: 14h 22m.

Frankfurt am Main (FRA) has the shortest average layover time for this route: 2h 11m.