Cheap flights from San Francisco to Prague from $333

In general, February is the cheapest month to fly from San Francisco to Prague. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $606. If you are unable to visit Prague during the month of February, then departing from San Francisco during the month November is also very affordable. Most momondo users find prices during this month for around $626.

You are more likely to see cheaper flights to Prague from San Francisco when booking weeks ahead of your departure date. In general, you can expect to find flights to Prague for around $772 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Prague from San Francisco for as low as $649 on momondo.

You could potentially save up to 3% on your flight if you consider stops on a San Francisco to Prague flight.

As of October 2026, prices for San Francisco to Prague flights are approximately 13% cheaper when compared to flights at the same time last year.

SWISS, British Airways, and KLM are the most popular carriers operating from San Francisco to Václav Havel Prague

Scandinavian Airlines, Condor and United Airlines are the top three most popular airlines that fly to Prague from San Francisco according to our data. Scandinavian Airlines is the first choice among our users, with 55% of people opting to fly with this airline when traveling to Prague. Keep in mind that there are 11 different airlines that fly to Prague on a routine basis, so you have a few additional options to choose from.

Copenhagen (CPH) was the most common stop: 44% of momondo users choosing 1-stop flights on this route connected there.

Flights via London (LHR) offer the lowest average round-trip price of $718.

Flights connecting via Copenhagen (CPH) have the shortest average one-way travel time: 13h 55m.

Zurich (ZRH) has the shortest average layover time for this route: 2h 00m.