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Cheap flights from Roanoke to Panama from $271

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Roanoke to Panama departing on 4/13. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Find the cheapest flights from Roanoke to Panama

Cheap round-trip flights

Enter your travel dates to find the best prices.
United Airlines Logo
7:59 pm - 2:14 pm
ROA
-
PTY
19h 15m
2 stops
United Airlines Logo
7:55 am - 9:57 am
PTY
-
ROA
25h 02m
2 stops
$551United Airlines
Tue, May 5 - Tue, May 12
Avianca Logo
10:30 am - 7:31 pm
ROA
-
PTY
10h 01m
2 stops
Avianca Logo
10:55 pm - 11:44 pm
PTY
-
ROA
23h 49m
2 stops
$571Avianca
Thu, Jul 30 - Sun, Aug 2
Delta Logo
6:00 am - 1:02 pm
ROA
-
PTY
8h 02m
1 stop
Delta Logo
2:27 pm - 12:25 am
PTY
-
ROA
8h 58m
1 stop
$587Delta
Mon, Apr 13 - Tue, Apr 28
United Airlines Logo
8:37 am - 7:31 pm
ROA
-
PTY
11h 54m
2 stops
United Airlines Logo
10:00 am - 12:37 am
PTY
-
ROA
13h 37m
2 stops
$591United Airlines
Mon, Apr 13 - Tue, Apr 28
United Airlines Logo
8:37 am - 7:31 pm
ROA
-
PTY
11h 54m
2 stops
United Airlines Logo
3:30 pm - 9:44 am
PTY
-
ROA
17h 14m
2 stops
$611United Airlines
Mon, Apr 13 - Tue, Apr 28
Delta Logo
6:00 am - 1:02 pm
ROA
-
PTY
8h 02m
1 stop
Delta Logo
2:27 pm - 12:25 am
PTY
-
ROA
8h 58m
1 stop
$617Delta
Mon, Apr 13 - Tue, Apr 28
United Airlines Logo
7:59 pm - 2:14 pm
ROA
-
PTY
19h 15m
2 stops
United Airlines Logo
3:30 pm - 9:44 am
PTY
-
ROA
17h 14m
2 stops
$632United Airlines
Sat, Apr 11 - Sun, Apr 19
United Airlines Logo
2:55 pm - 2:14 pm
ROA
-
PTY
24h 19m
2 stops
United Airlines Logo
3:30 pm - 5:05 pm
PTY
-
ROA
24h 35m
2 stops
$679United Airlines
Thu, Apr 2 - Sat, Apr 4
Delta Logo
6:00 am - 12:50 pm
ROA
-
PTY
7h 50m
1 stop
Delta Logo
2:15 pm - 12:34 am
PTY
-
ROA
9h 19m
1 stop
$715Delta
Sat, May 9 - Sun, May 17
Delta Logo
6:00 am - 1:03 pm
ROA
-
PTY
8h 03m
1 stop
Delta Logo
2:27 pm - 12:25 am
PTY
-
ROA
8h 58m
1 stop
$850Delta
Sat, Apr 11 - Sun, Apr 19

Delta flights from Roanoke to Panama

Our best Delta deals on Roanoke to Panama flight tickets
Delta
Apr 13
ROA6:00 amRoanoke
8h 02m
1 stop
PTY1:02 pmPanama City Tocumen Intl
Apr 28
PTY2:27 pmPanama City Tocumen Intl
8h 58m
1 stop
ROA12:25 amRoanoke
$587
Delta
Apr 13
ROA6:00 amRoanoke
8h 02m
1 stop
PTY1:02 pmPanama City Tocumen Intl
Apr 28
PTY2:27 pmPanama City Tocumen Intl
8h 58m
1 stop
ROA12:25 amRoanoke
$617
Delta
May 9
ROA6:00 amRoanoke
7h 50m
1 stop
PTY12:50 pmPanama City Tocumen Intl
May 17
PTY2:15 pmPanama City Tocumen Intl
9h 19m
1 stop
ROA12:34 amRoanoke
$715

Avianca flights from Roanoke to Panama

Our best Avianca deals on Roanoke to Panama flight tickets
Avianca
Jul 30
ROA10:30 amRoanoke
10h 01m
2 stops
PTY7:31 pmPanama City Tocumen Intl
Aug 2
PTY10:55 pmPanama City Tocumen Intl
23h 49m
2 stops
ROA11:44 pmRoanoke
$571
Avianca
Apr 11
ROA7:59 pmRoanoke
19h 56m
3 stops
PTY2:55 pmPanama City Tocumen Intl
Apr 19
PTY3:10 pmPanama City Tocumen Intl
27h 00m
2 stops
ROA7:10 pmRoanoke
$1,303
Avianca
Apr 11
ROA7:59 pmRoanoke
19h 56m
3 stops
PTY2:55 pmPanama City Tocumen Intl
Apr 19
PTY5:55 pmPanama City Tocumen Intl
24h 15m
2 stops
ROA7:10 pmRoanoke
$1,538

momondo Fare Finder

 
Customize your flight search to find flights from Roanoke to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated March 22, 2026.
Use the filters below to find and compare flights from Roanoke to Panama that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

RoanokePanama City

ROA - PTY

ROAPTY

Roanoke

Tue 5/5

7:59 pm-2:14 pm

2 stops19h 15m

Panama City Tocumen Intl

Tue 5/12

7:55 am-9:57 am

2 stops25h 02m

$551

RoanokePanama City

ROA - PTY

ROAPTY

Roanoke

Thu 7/30

10:30 am-7:31 pm

2 stops10h 01m

Panama City Tocumen Intl

Sun 8/2

10:55 pm-11:44 pm

2 stops23h 49m

$571
Quickest round-trip

RoanokePanama City

ROA - PTY

ROAPTY

Roanoke

Mon 4/13

6:00 am-1:02 pm

1 stop8h 02m

Panama City Tocumen Intl

Tue 4/28

2:27 pm-12:25 am

1 stop8h 58m

$587

RoanokePanama City

ROA - PTY

ROAPTY

Roanoke

Mon 4/13

8:37 am-7:31 pm

2 stops11h 54m

Panama City Tocumen Intl

Tue 4/28

10:00 am-12:37 am

2 stops13h 37m

$591

RoanokePanama City

ROA - PTY

ROAPTY

Roanoke

Mon 4/13

8:37 am-7:31 pm

2 stops11h 54m

Panama City Tocumen Intl

Tue 4/28

3:30 pm-9:44 am

2 stops17h 14m

$611

RoanokePanama City

ROA - PTY

ROAPTY

Roanoke

Mon 4/13

6:00 am-1:02 pm

1 stop8h 02m

Panama City Tocumen Intl

Tue 4/28

2:27 pm-12:25 am

1 stop8h 58m

$617

RoanokePanama City

ROA - PTY

ROAPTY

Roanoke

Sat 4/11

7:59 pm-2:14 pm

2 stops19h 15m

Panama City Tocumen Intl

Sun 4/19

3:30 pm-9:44 am

2 stops17h 14m

$632

RoanokePanama City

ROA - PTY

ROAPTY

Roanoke

Thu 4/2

2:55 pm-2:14 pm

2 stops24h 19m

Panama City Tocumen Intl

Sat 4/4

3:30 pm-5:05 pm

2 stops24h 35m

$679

RoanokePanama City

ROA - PTY

ROAPTY

Roanoke

Sat 5/9

6:00 am-12:50 pm

1 stop7h 50m

Panama City Tocumen Intl

Sun 5/17

2:15 pm-12:34 am

1 stop9h 19m

$715

RoanokePanama City

ROA - PTY

ROAPTY

Roanoke

Sat 4/11

6:00 am-1:03 pm

1 stop8h 03m

Panama City Tocumen Intl

Sun 4/19

2:27 pm-12:25 am

1 stop8h 58m

$850

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 13 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Roanoke to Panama

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Can stopping save me money on Roanoke to Panama flights?

You could potentially save up to 59% on your flight if you consider stops on a Roanoke to Panama flight.

Cheap Roanoke to Panama flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Roanoke to Panama

Fastest flight time

8h 02m

Direct flights

None
The fastest flight from Roanoke to Panama takes 8h 02m
There are no direct flights from Roanoke to Panama. There are no popular flight routes from Roanoke to Panama.
Search flight deals

  • When did momondo last update prices for flights from Roanoke Airport to Panama?

    Prices for flights from Roanoke Airport to Panama refresh daily.

  • How old do you have to be to fly from Roanoke Airport to Panama?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Roanoke Airport to Panama.

  • What documentation or ID do you need to fly to Panama?

    The required travel and health documents for your Panama trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Panama. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Why use momondo?

Why should I use momondo to find a flight deal from Roanoke to Panama?

Finding the right flight to Panama from Roanoke is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Panama quick and easy, saving you time and money.

Can I find flights from Roanoke to Panama with flexible booking policies on momondo?

Yes. All flights to Panama from Roanoke on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Roanoke to Panama?

momondo helps you find the best flight between Roanoke and Panama by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Roanoke to Panama right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Roanoke to Panama now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Panama and let you know when they change.

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