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Cheap flights from Roanoke to Panama from $269

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Roanoke to Panama departing on 6/16. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Roanoke to Panama

Cheap round-trip flights

Enter your travel dates to find the best prices.
United Airlines Logo
10:39 am - 7:31 pm
ROA
-
PTY
33h 52m
2 stops
United Airlines Logo
7:55 am - 9:46 am
PTY
-
ROA
24h 51m
2 stops
$564United Airlines
Tue, Jun 16 - Wed, Jul 29
United Airlines Logo
6:15 am - 7:31 pm
ROA
-
PTY
14h 16m
2 stops
United Airlines Logo
10:55 pm - 9:03 pm
PTY
-
ROA
21h 08m
2 stops
$611United Airlines
Mon, Jun 1 - Wed, Jul 1
United Airlines Logo
3:00 pm - 2:14 pm
ROA
-
PTY
24h 14m
2 stops
United Airlines Logo
9:45 am - 11:43 pm
PTY
-
ROA
12h 58m
2 stops
$612United Airlines
Sat, Oct 17 - Wed, Oct 21
United Airlines Logo
6:15 am - 7:31 pm
ROA
-
PTY
14h 16m
2 stops
United Airlines Logo
10:55 pm - 9:03 pm
PTY
-
ROA
21h 08m
2 stops
$691United Airlines
Mon, Jun 1 - Wed, Jul 1
Delta Logo
6:00 am - 12:50 pm
ROA
-
PTY
7h 50m
1 stop
Delta Logo
2:24 pm - 12:32 am
PTY
-
ROA
9h 08m
1 stop
$693Delta
Mon, Jun 1 - Wed, Jul 1
Delta Logo
6:00 am - 1:09 pm
ROA
-
PTY
8h 09m
1 stop
Delta Logo
2:24 pm - 12:25 am
PTY
-
ROA
9h 01m
1 stop
$1,086Delta
Tue, Jun 16 - Wed, Jul 29
American Airlines Logo
7:58 pm - 12:13 pm
ROA
-
PTY
17h 15m
3 stops
American Airlines Logo
1:14 pm - 11:59 pm
PTY
-
ROA
9h 45m
2 stops
$2,621American Airlines
Tue, Jun 16 - Wed, Jul 29
United Airlines Logo
10:39 am - 7:31 pm
ROA
-
PTY
9h 52m
2 stops
United Airlines Logo
10:29 pm - 1:55 pm
PTY
-
ROA
14h 26m
1 stop
$4,321United Airlines
Mon, Jun 1 - Wed, Jul 1
United Airlines Logo
6:15 am - 1:31 pm
ROA
-
PTY
8h 16m
1 stop
United Airlines Logo
9:13 am - 7:07 pm
PTY
-
ROA
8h 54m
1 stop
$4,725United Airlines
Sat, Oct 17 - Wed, Oct 21
United Airlines Logo
6:15 am - 5:10 pm
ROA
-
PTY
11h 55m
2 stops
United Airlines Logo
10:29 pm - 9:42 am
PTY
-
ROA
10h 13m
1 stop
$7,915United Airlines
Tue, Jun 16 - Wed, Jul 29

United Airlines flights from Roanoke to Panama

Our best United Airlines deals on Roanoke to Panama flight tickets
United Airlines
Jun 16
ROA10:39 amRoanoke
33h 52m
2 stops
PTY7:31 pmPanama City Tocumen Intl
Jul 29
PTY7:55 amPanama City Tocumen Intl
24h 51m
2 stops
ROA9:46 amRoanoke
$564
United Airlines
Jun 1
ROA6:15 amRoanoke
14h 16m
2 stops
PTY7:31 pmPanama City Tocumen Intl
Jul 1
PTY10:55 pmPanama City Tocumen Intl
21h 08m
2 stops
ROA9:03 pmRoanoke
$611
United Airlines
Oct 17
ROA3:00 pmRoanoke
24h 14m
2 stops
PTY2:14 pmPanama City Tocumen Intl
Oct 21
PTY9:45 amPanama City Tocumen Intl
12h 58m
2 stops
ROA11:43 pmRoanoke
$612

Delta flights from Roanoke to Panama

Our best Delta deals on Roanoke to Panama flight tickets
Delta
Jun 1
ROA6:00 amRoanoke
7h 50m
1 stop
PTY12:50 pmPanama City Tocumen Intl
Jul 1
PTY2:24 pmPanama City Tocumen Intl
9h 08m
1 stop
ROA12:32 amRoanoke
$693
Delta
Jun 16
ROA6:00 amRoanoke
8h 09m
1 stop
PTY1:09 pmPanama City Tocumen Intl
Jul 29
PTY2:24 pmPanama City Tocumen Intl
9h 01m
1 stop
ROA12:25 amRoanoke
$1,086

momondo Fare Finder

 
Customize your flight search to find flights from Roanoke to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated May 11, 2026.
Use the filters below to find and compare flights from Roanoke to Panama that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

RoanokePanama City

ROA - PTY

ROAPTY

Roanoke

Tue 6/16

10:39 am-7:31 pm

2 stops33h 52m

Panama City Tocumen Intl

Wed 7/29

7:55 am-9:46 am

2 stops24h 51m

$564

RoanokePanama City

ROA - PTY

ROAPTY

Roanoke

Mon 6/1

6:15 am-7:31 pm

2 stops14h 16m

Panama City Tocumen Intl

Wed 7/1

10:55 pm-9:03 pm

2 stops21h 08m

$611

RoanokePanama City

ROA - PTY

ROAPTY

Roanoke

Sat 10/17

3:00 pm-2:14 pm

2 stops24h 14m

Panama City Tocumen Intl

Wed 10/21

9:45 am-11:43 pm

2 stops12h 58m

$612

RoanokePanama City

ROA - PTY

ROAPTY

Roanoke

Mon 6/1

6:15 am-7:31 pm

2 stops14h 16m

Panama City Tocumen Intl

Wed 7/1

10:55 pm-9:03 pm

2 stops21h 08m

$691
Quickest round-trip

RoanokePanama City

ROA - PTY

ROAPTY

Roanoke

Mon 6/1

6:00 am-12:50 pm

1 stop7h 50m

Panama City Tocumen Intl

Wed 7/1

2:24 pm-12:32 am

1 stop9h 08m

$693

RoanokePanama City

ROA - PTY

ROAPTY

Roanoke

Tue 6/16

6:00 am-1:09 pm

1 stop8h 09m

Panama City Tocumen Intl

Wed 7/29

2:24 pm-12:25 am

1 stop9h 01m

$1,086

RoanokePanama City

ROA - PTY

ROAPTY

Roanoke

Tue 6/16

7:58 pm-12:13 pm

3 stops17h 15m

Panama City Tocumen Intl

Wed 7/29

1:14 pm-11:59 pm

2 stops9h 45m

$2,621

RoanokePanama City

ROA - PTY

ROAPTY

Roanoke

Mon 6/1

10:39 am-7:31 pm

2 stops9h 52m

Panama City Tocumen Intl

Wed 7/1

10:29 pm-1:55 pm

1 stop14h 26m

$4,321

RoanokePanama City

ROA - PTY

ROAPTY

Roanoke

Sat 10/17

6:15 am-1:31 pm

1 stop8h 16m

Panama City Tocumen Intl

Wed 10/21

9:13 am-7:07 pm

1 stop8h 54m

$4,725

RoanokePanama City

ROA - PTY

ROAPTY

Roanoke

Tue 6/16

6:15 am-5:10 pm

2 stops11h 55m

Panama City Tocumen Intl

Wed 7/29

10:29 pm-9:42 am

1 stop10h 13m

$7,915

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 13 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Roanoke to Panama

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Can stopping save me money on Roanoke to Panama flights?

You could potentially save up to 6% on your flight if you consider stops on a Roanoke to Panama flight.

Cheap Roanoke to Panama flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Roanoke to Panama

Fastest flight time

14h 16m

Direct flights

None
The fastest flight from Roanoke to Panama takes 14h 16m
There are no direct flights from Roanoke to Panama. There are no popular flight routes from Roanoke to Panama.
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Frequently asked questions about flying from Roanoke to Panama

  • When did momondo last update prices for flights from Roanoke Airport to Panama?

    Prices for flights from Roanoke Airport to Panama refresh daily.

  • How old do you have to be to fly from Roanoke Airport to Panama?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Roanoke Airport to Panama.

  • What documentation or ID do you need to fly to Panama?

    The required travel and health documents for your Panama trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Panama. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Why use momondo?

Why should I use momondo to find a flight deal from Roanoke to Panama?

Finding the right flight to Panama from Roanoke is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Panama quick and easy, saving you time and money.

Can I find flights from Roanoke to Panama with flexible booking policies on momondo?

Yes. All flights to Panama from Roanoke on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Roanoke to Panama?

momondo helps you find the best flight between Roanoke and Panama by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Roanoke to Panama right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Roanoke to Panama now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Panama and let you know when they change.

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