Cheap flights from Raleigh to Panama from $181

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Raleigh to Panama departing on 2/15. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Raleigh to Panama

Cheap round-trip flights

Enter your travel dates to find the best prices.
Copa Airlines Logo
4:18 pm - 7:46 pm
RDU
-
PTY
4h 28mnonstop
Copa Airlines Logo
8:57 am - 2:29 pm
PTY
-
RDU
4h 32mnonstop
$462Copa Airlines
Wed, Apr 22 - Fri, Apr 24
United Airlines Logo
6:56 pm - 4:10 am
RDU
-
PTY
10h 14m
1 stop
United Airlines Logo
10:55 pm - 9:16 am
PTY
-
RDU
9h 21m
1 stop
$468United Airlines
Sat, Mar 14 - Sun, Mar 22
United Airlines Logo
6:15 am - 6:37 pm
RDU
-
PTY
13h 22m
2 stops
United Airlines Logo
9:45 am - 9:48 pm
PTY
-
RDU
11h 03m
1 stop
$477United Airlines
Mon, Apr 20 - Sun, Apr 26
Copa Airlines Logo
6:00 am - 7:31 pm
RDU
-
PTY
14h 31m
1 stop
Copa Airlines Logo
7:55 am - 10:06 pm
PTY
-
RDU
13h 11m
1 stop
$480Copa Airlines
Fri, May 22 - Tue, May 26
American Airlines Logo
8:19 pm - 2:20 pm
RDU
-
PTY
19h 01m
2 stops
American Airlines Logo
3:10 pm - 10:33 am
PTY
-
RDU
18h 23m
2 stops
$481American Airlines
Sun, Mar 8 - Tue, Mar 17
Copa Airlines Logo
4:19 pm - 7:46 pm
RDU
-
PTY
4h 27mnonstop
Copa Airlines Logo
8:57 am - 2:29 pm
PTY
-
RDU
4h 32mnonstop
$482Copa Airlines
Fri, May 22 - Mon, May 25
United Airlines Logo
6:29 am - 7:38 pm
RDU
-
PTY
13h 09m
2 stops
United Airlines Logo
4:41 pm - 3:40 pm
PTY
-
RDU
22h 59m
1 stop
$487United Airlines
Sun, Feb 15 - Tue, Feb 24
Multiple Airlines Logo
2:45 pm - 6:55 pm
RDU
-
PTY
28h 10m
3 stops
Multiple Airlines Logo
7:50 pm - 1:50 pm
PTY
-
RDU
18h 00m
2 stops
$488Multiple Airlines
Sat, Jan 31 - Wed, Feb 4
Copa Airlines Logo
6:05 am - 8:02 pm
RDU
-
PTY
13h 57m
1 stop
Copa Airlines Logo
3:41 pm - 11:49 am
PTY
-
RDU
19h 08m
1 stop
$490Copa Airlines
Fri, Mar 6 - Tue, Mar 10
Multiple Airlines Logo
8:04 pm - 4:06 pm
RDU
-
PTY
20h 02m
1 stop
Multiple Airlines Logo
9:45 am - 9:22 pm
PTY
-
RDU
35h 37m
2 stops
$491Multiple Airlines
Sat, Feb 14 - Thu, Feb 26

Copa Airlines flights from Raleigh to Panama

Our best Copa Airlines deals on Raleigh to Panama flight tickets
Copa Airlines
Apr 22
RDU4:18 pmRaleigh-Durham
4h 28m
PTY7:46 pmPanama City Tocumen Intl
Apr 24
PTY8:57 amPanama City Tocumen Intl
4h 32m
RDU2:29 pmRaleigh-Durham
$462
Copa Airlines
May 22
RDU6:00 amRaleigh-Durham
14h 31m
1 stop
PTY7:31 pmPanama City Tocumen Intl
May 26
PTY7:55 amPanama City Tocumen Intl
13h 11m
1 stop
RDU10:06 pmRaleigh-Durham
$480
Copa Airlines
Mar 6
RDU6:05 amRaleigh-Durham
13h 57m
1 stop
PTY8:02 pmPanama City Tocumen Intl
Mar 10
PTY3:41 pmPanama City Tocumen Intl
19h 08m
1 stop
RDU11:49 amRaleigh-Durham
$490

American Airlines flights from Raleigh to Panama

Our best American Airlines deals on Raleigh to Panama flight tickets
American Airlines
Mar 8
RDU8:19 pmRaleigh-Durham
19h 01m
2 stops
PTY2:20 pmPanama City Tocumen Intl
Mar 17
PTY3:10 pmPanama City Tocumen Intl
18h 23m
2 stops
RDU10:33 amRaleigh-Durham
$481
American Airlines
Mar 3
RDU5:41 pmRaleigh-Durham
19h 59m
2 stops
PTY1:40 pmPanama City Tocumen Intl
Mar 12
PTY1:40 pmPanama City Tocumen Intl
17h 23m
2 stops
RDU8:03 amRaleigh-Durham
$501
American Airlines
Mar 7
RDU6:33 pmRaleigh-Durham
19h 47m
2 stops
PTY2:20 pmPanama City Tocumen Intl
Mar 11
PTY3:10 pmPanama City Tocumen Intl
7h 49m
1 stop
RDU11:59 pmRaleigh-Durham
$505

momondo Fare Finder

 
Customize your flight search to find flights from Raleigh to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated January 21, 2026.
Use the filters below to find and compare flights from Raleigh to Panama that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

RaleighPanama City

RDU - PTY

RDUPTY

Raleigh-Durham

Wed 4/22

4:18 pm-7:46 pm

Nonstop4h 28m

Panama City Tocumen Intl

Fri 4/24

8:57 am-2:29 pm

Nonstop4h 32m

$462

RaleighPanama City

RDU - PTY

RDUPTY

Raleigh-Durham

Sat 3/14

6:56 pm-4:10 am

1 stop10h 14m

Panama City Tocumen Intl

Sun 3/22

10:55 pm-9:16 am

1 stop9h 21m

$468

RaleighPanama City

RDU - PTY

RDUPTY

Raleigh-Durham

Mon 4/20

6:15 am-6:37 pm

2 stops13h 22m

Panama City Tocumen Intl

Sun 4/26

9:45 am-9:48 pm

1 stop11h 03m

$477

RaleighPanama City

RDU - PTY

RDUPTY

Raleigh-Durham

Fri 5/22

6:00 am-7:31 pm

1 stop14h 31m

Panama City Tocumen Intl

Tue 5/26

7:55 am-10:06 pm

1 stop13h 11m

$480

RaleighPanama City

RDU - PTY

RDUPTY

Raleigh-Durham

Sun 3/8

8:19 pm-2:20 pm

2 stops19h 01m

Panama City Tocumen Intl

Tue 3/17

3:10 pm-10:33 am

2 stops18h 23m

$481

RaleighPanama City

RDU - PTY

RDUPTY

Raleigh-Durham

Fri 5/22

4:19 pm-7:46 pm

Nonstop4h 27m

Panama City Tocumen Intl

Mon 5/25

8:57 am-2:29 pm

Nonstop4h 32m

$482

RaleighPanama City

RDU - PTY

RDUPTY

Raleigh-Durham

Sun 2/15

6:29 am-7:38 pm

2 stops13h 09m

Panama City Tocumen Intl

Tue 2/24

4:41 pm-3:40 pm

1 stop22h 59m

$487

RaleighPanama City

RDU - PTY

RDUPTY

Raleigh-Durham

Sat 1/31

2:45 pm-6:55 pm

3 stops28h 10m

Panama City Tocumen Intl

Wed 2/4

7:50 pm-1:50 pm

2 stops18h 00m

$488

RaleighPanama City

RDU - PTY

RDUPTY

Raleigh-Durham

Fri 3/6

6:05 am-8:02 pm

1 stop13h 57m

Panama City Tocumen Intl

Tue 3/10

3:41 pm-11:49 am

1 stop19h 08m

$490

RaleighPanama City

RDU - PTY

RDUPTY

Raleigh-Durham

Sat 2/14

8:04 pm-4:06 pm

1 stop20h 02m

Panama City Tocumen Intl

Thu 2/26

9:45 am-9:22 pm

2 stops35h 37m

$491

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Panama from

How to get the cheapest flight ticket from Raleigh to Panama

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Panama?

The month of October is, on average, the cheapest month to fly to Panama from Raleigh, with most prices found around $402. If you don’t want to visit Panama in October, then you should wait until September to fly from Raleigh, when ticket prices are also cheap, with an average price of $417.

What is the cheapest day to depart on your flight to Panama?

According to our data, Tuesday is the cheapest day to fly to Panama from Raleigh. The lowest ticket price found for a Tuesday departure recently was $346. Keep in mind that prices can always vary depending on your route and whether or not you are flying domestic or international. When flying out on a Saturday, the most expensive travel day of the week, you can expect to see flight prices from Raleigh to Panama for around $738.

What is the cheapest Raleigh-Durham to Panama flight route?

Fly from Raleigh-Durham to Panama City Tocumen Intl for the best Raleigh-Durham - Panama flight prices

How far in advance should I book a flight to Panama?

You are more likely to see cheaper flights to Panama from Raleigh when booking weeks ahead of your departure date. In general, you can expect to find flights to Panama for around $513 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Panama from Raleigh for as low as $407 on momondo.

What cabin class options are available on Raleigh-Durham to Panama flights?

There are 3 cabin classes available to choose from on Raleigh-Durham to Panama flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Raleigh to Panama flights?

You could potentially save up to 51% on your flight if you consider stops on a Raleigh to Panama flight.

Cheap Raleigh to Panama flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Raleigh to Panama

Best Price Found

$183

Fastest flight time

4h 25m

Direct flights

Mon, Tue, Thu and Sat

Airports in Panama

21 airports
The best one-way flight to Panama from Raleigh in the past 72 hours is $183. The best round-trip flight deal from Raleigh to Panama found on momondo in the last 72 hours is $293.
The fastest flight from Raleigh to Panama takes 4h 25m
Direct flights go from Raleigh to Panama on Monday, Tuesday, Thursday and Saturday. There are no airlines offering direct flights.
There are 21 airports in Panama. From Raleigh there are direct flights to Panama City Tocumen Intl (PTY).
  • When did momondo last update prices for flights from Raleigh-Durham Airport to Panama?

    Prices for flights from Raleigh-Durham Airport to Panama are updated daily.

  • How many operators does momondo search for flights from Raleigh-Durham Airport to Panama?

  • How old do you have to be to fly from Raleigh-Durham Airport to Panama?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Raleigh-Durham Airport to Panama.

  • What documentation or ID do you need to fly to Panama?

    The required travel and health documents for your Panama trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Panama. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular plane model from Raleigh to Panama?

Best airlines flying from Raleigh to Panama

Compare and see reviews for airlines that fly from Raleigh to Panama with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $249Free CancellationRating
7.2
11,168 reviews
Search American Airlines flights
Copa AirlinesPriceFrom $352Free CancellationRating
7.6
1,559 reviews
Search Copa Airlines flights
DeltaPriceFrom $367Free CancellationRating
7.9
8,087 reviews
Search Delta flights
United AirlinesPriceFrom $409Free CancellationRating
7.4
9,189 reviews
Search United Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Raleigh to Panama?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Panama from Raleigh.

Can I find flights from Raleigh to Panama with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Raleigh to Panama flights to just show those with flexible booking policies.

How can momondo help me find flights from Raleigh to Panama?

momondo helps you find the best flight between Raleigh and Panama by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Raleigh to Panama right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Panama, momondo offers a useful price alert feature which will track prices for flights to Panama from Raleigh and alert you when they change.

An easier way to manage your Panama trip

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1 adult
Fri 2/20
Fri 2/27

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