Cheap flights from Raleigh to Panama from $267

The month of January is, on average, the cheapest month to fly to Panama from Raleigh, with most prices found around $489. If you don’t want to visit Panama in January, then you should wait until April to fly from Raleigh, when ticket prices are also cheap, with an average price of $513.

According to our data, Tuesday is the cheapest day to fly to Panama from Raleigh. The lowest ticket price found for a Tuesday departure recently was $397. Keep in mind that prices can always vary depending on your route and whether or not you are flying domestic or international. When flying out on a Saturday, the most expensive travel day of the week, you can expect to see flight prices from Raleigh to Panama for around $817.

Fly from Raleigh-Durham to Panama City Tocumen Intl for the best Raleigh-Durham - Panama flight prices

You are more likely to see cheaper flights to Panama from Raleigh when booking weeks ahead of your departure date. In general, you can expect to find flights to Panama for around $615 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Panama from Raleigh for as low as $526 on momondo.

There are 3 cabin classes available to choose from on Raleigh to Panama flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

You could potentially save up to 11% on your flight if you consider stops on a Raleigh to Panama flight.

Avianca and Aeromexico are the most popular carriers operating from Raleigh-Durham to Panama

Copa Airlines, American Airlines and Delta are the top three most popular airlines that fly to Panama from Raleigh according to our data. Copa Airlines is the first choice among our users, with 69% of people opting to fly with this airline when traveling to Panama. Keep in mind that there are 4 different airlines that fly to Panama on a routine basis, so you have a few additional options to choose from.

Historically, on average around 8% of flights between Raleigh and Panama have experienced a delay on any given week. The average delay length over the past 12 months has been 154 minutes.

Generally, flights departing in the early afternoon tend to experience fewer delays. Flights in the early afternoon have, in the past, seen delays more frequently in comparison.

Tuesday is statistically the day of the week which experiences the fewest number of delays on this flight route. Saturday has historically seen more delays on average compared to the rest of the week.

According to our data, Copa Airlines have had the least number of delays on this route over the last 12 months; with about 8% of their flights experiencing any sort of delay.

1 flights are operational daily from Raleigh to Panama as of August 2026. The most popular departure time for this route is 4:00PM, with 100% of flights per day taking off in the afternoon.

8 flights are operational weekly from Raleigh to Panama as of August 2026. The most popular departure day for this route is Mon, with 25% of flights per week taking off on this day.