Cheap flights from Raleigh to Panama from $235

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Raleigh to Panama departing on 1/8. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Multiple Airlines Logo
6:00 am - 3:55 pmRDU-PTY
9h 55m2 stops
Multiple Airlines Logo
9:33 pm - 2:21 pmPTY-RDU
16h 48m1 stop
$431Multiple Airlines
Find Deal
Sun, Dec 7 - Thu, Dec 11
Copa Airlines Logo
3:09 pm - 7:46 pmRDU-PTY
4h 37mnonstop
Copa Airlines Logo
8:57 am - 1:15 pmPTY-RDU
4h 18mnonstop
$441Copa Airlines
Find Deal
Wed, Jan 14 - Mon, Jan 19
American Airlines Logo
6:00 am - 1:27 pmRDU-PTY
7h 27m1 stop
American Airlines Logo
4:04 pm - 8:02 amPTY-RDU
15h 58m2 stops
$446American Airlines
Find Deal
Wed, Feb 11 - Thu, Feb 19
United Airlines Logo
6:15 am - 5:07 pmRDU-PTY
34h 52m2 stops
United Airlines Logo
4:41 pm - 12:14 pmPTY-RDU
19h 33m1 stop
$447United Airlines
Find Deal
Sun, Jan 18 - Fri, Jan 23
United Airlines Logo
9:25 am - 8:02 pmRDU-PTY
10h 37m1 stop
United Airlines Logo
8:55 am - 10:43 pmPTY-RDU
13h 48m1 stop
$456United Airlines
Find Deal
Fri, Jan 30 - Sun, Feb 8
Multiple Airlines Logo
3:21 pm - 8:06 amRDU-PTY
16h 45m1 stop
Multiple Airlines Logo
10:25 am - 8:52 pmPTY-RDU
10h 27m2 stops
$457Multiple Airlines
Find Deal
Mon, Dec 8 - Thu, Dec 11
American Airlines Logo
7:57 pm - 1:27 pmRDU-PTY
17h 30m1 stop
American Airlines Logo
2:27 pm - 9:55 amPTY-RDU
19h 28m2 stops
$460American Airlines
Find Deal
Mon, Jan 5 - Mon, Jan 12
Copa Airlines Logo
3:09 pm - 7:46 pmRDU-PTY
4h 37mnonstop
Copa Airlines Logo
8:57 am - 1:15 pmPTY-RDU
4h 18mnonstop
$465Copa Airlines
Find Deal
Mon, Jan 5 - Mon, Jan 12
Copa Airlines Logo
3:14 pm - 7:46 pmRDU-PTY
4h 32mnonstop
Copa Airlines Logo
8:57 am - 2:23 pmPTY-RDU
4h 26mnonstop
$471Copa Airlines
Find Deal
Sun, Mar 1 - Sun, Mar 15
United Airlines Logo
4:47 pm - 7:38 pmRDU-PTY
26h 51m1 stop
United Airlines Logo
4:41 pm - 12:12 pmPTY-RDU
19h 31m1 stop
$475United Airlines
Find Deal
Fri, Feb 13 - Sat, Feb 21

Copa Airlines flights from Raleigh to Panama

Our best Copa Airlines deals on Raleigh to Panama flight tickets
Copa Airlines
Jan 14
RDU3:09 pmRaleigh-Durham
4h 37m
PTY7:46 pmPanama City Tocumen Intl
Jan 19
PTY8:57 amPanama City Tocumen Intl
4h 18m
RDU1:15 pmRaleigh-Durham
Copa Airlines
Jan 5
RDU3:09 pmRaleigh-Durham
4h 37m
PTY7:46 pmPanama City Tocumen Intl
Jan 12
PTY8:57 amPanama City Tocumen Intl
4h 18m
RDU1:15 pmRaleigh-Durham
Copa Airlines
Mar 1
RDU3:14 pmRaleigh-Durham
4h 32m
PTY7:46 pmPanama City Tocumen Intl
Mar 15
PTY8:57 amPanama City Tocumen Intl
4h 26m
RDU2:23 pmRaleigh-Durham

American Airlines flights from Raleigh to Panama

Our best American Airlines deals on Raleigh to Panama flight tickets
American Airlines
Feb 11
RDU6:00 amRaleigh-Durham
7h 27m
1 stop
PTY1:27 pmPanama City Tocumen Intl
Feb 19
PTY4:04 pmPanama City Tocumen Intl
15h 58m
2 stops
RDU8:02 amRaleigh-Durham
American Airlines
Jan 5
RDU7:57 pmRaleigh-Durham
17h 30m
1 stop
PTY1:27 pmPanama City Tocumen Intl
Jan 12
PTY2:27 pmPanama City Tocumen Intl
19h 28m
2 stops
RDU9:55 amRaleigh-Durham
American Airlines
Feb 27
RDU6:29 pmRaleigh-Durham
19h 11m
1 stop
PTY1:40 pmPanama City Tocumen Intl
Mar 2
PTY4:04 pmPanama City Tocumen Intl
21h 13m
2 stops
RDU1:17 pmRaleigh-Durham

momondo Fare Finder

 
Customize your flight search to find flights from Raleigh to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated November 21, 2025.
Use the filters below to find and compare flights from Raleigh to Panama that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

RaleighPanama City

RDU - PTY

RDUPTY

Raleigh-Durham

Sun 12/7

6:00 am-3:55 pm

2 stops9h 55m

Panama City Tocumen Intl

Thu 12/11

9:33 pm-2:21 pm

1 stop16h 48m

$431

RaleighPanama City

RDU - PTY

RDUPTY

Raleigh-Durham

Wed 1/14

3:09 pm-7:46 pm

Nonstop4h 37m

Panama City Tocumen Intl

Mon 1/19

8:57 am-1:15 pm

Nonstop4h 18m

$441

RaleighPanama City

RDU - PTY

RDUPTY

Raleigh-Durham

Wed 2/11

6:00 am-1:27 pm

1 stop7h 27m

Panama City Tocumen Intl

Thu 2/19

4:04 pm-8:02 am

2 stops15h 58m

$446

RaleighPanama City

RDU - PTY

RDUPTY

Raleigh-Durham

Sun 1/18

6:15 am-5:07 pm

2 stops34h 52m

Panama City Tocumen Intl

Fri 1/23

4:41 pm-12:14 pm

1 stop19h 33m

$447

RaleighPanama City

RDU - PTY

RDUPTY

Raleigh-Durham

Fri 1/30

9:25 am-8:02 pm

1 stop10h 37m

Panama City Tocumen Intl

Sun 2/8

8:55 am-10:43 pm

1 stop13h 48m

$456

RaleighPanama City

RDU - PTY

RDUPTY

Raleigh-Durham

Mon 12/8

3:21 pm-8:06 am

1 stop16h 45m

Panama City Tocumen Intl

Thu 12/11

10:25 am-8:52 pm

2 stops10h 27m

$457

RaleighPanama City

RDU - PTY

RDUPTY

Raleigh-Durham

Mon 1/5

7:57 pm-1:27 pm

1 stop17h 30m

Panama City Tocumen Intl

Mon 1/12

2:27 pm-9:55 am

2 stops19h 28m

$460

RaleighPanama City

RDU - PTY

RDUPTY

Raleigh-Durham

Mon 1/5

3:09 pm-7:46 pm

Nonstop4h 37m

Panama City Tocumen Intl

Mon 1/12

8:57 am-1:15 pm

Nonstop4h 18m

$465

RaleighPanama City

RDU - PTY

RDUPTY

Raleigh-Durham

Sun 3/1

3:14 pm-7:46 pm

Nonstop4h 32m

Panama City Tocumen Intl

Sun 3/15

8:57 am-2:23 pm

Nonstop4h 26m

$471

RaleighPanama City

RDU - PTY

RDUPTY

Raleigh-Durham

Fri 2/13

4:47 pm-7:38 pm

1 stop26h 51m

Panama City Tocumen Intl

Sat 2/21

4:41 pm-12:12 pm

1 stop19h 31m

$475

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Panama from

How to get the cheapest flight ticket from Raleigh to Panama

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Panama?

The month of October is, on average, the cheapest month to fly to Panama from Raleigh, with most prices found around $402. If you don’t want to visit Panama in October, then you should wait until September to fly from Raleigh, when ticket prices are also cheap, with an average price of $418.

What is the cheapest day to depart on your flight to Panama?

According to our data, Tuesday is the cheapest day to fly to Panama from Raleigh. The lowest ticket price found for a Tuesday departure recently was $317. Keep in mind that prices can always vary depending on your route and whether or not you are flying domestic or international. When flying out on a Saturday, the most expensive travel day of the week, you can expect to see flight prices from Raleigh to Panama for around $856.

What is the cheapest time of day to depart on your flight to Panama?

At noon is the cheapest time of day to fly from Raleigh to Panama when you can find flight prices for as low as $413. Flying to Panama at noon is an ideal time because this is during off-peak travel hours. In the morning is when there is more demand to fly to Panama, so prices are often more expensive at around $553 per ticket.

What is the cheapest Raleigh-Durham to Panama flight route?

Fly from Raleigh-Durham to Panama City Tocumen Intl for the best Raleigh-Durham - Panama flight prices

How far in advance should I book a flight to Panama?

You are more likely to see cheaper flights to Panama from Raleigh when booking weeks ahead of your departure date. In general, you can expect to find flights to Panama for around $491 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Panama from Raleigh for as low as $406 on momondo.

What cabin class options are available on Raleigh-Durham to Panama flights?

There are 3 cabin classes available to choose from on Raleigh-Durham to Panama flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Raleigh to Panama flights?

You could potentially save up to 73% on your flight if you consider stops on a Raleigh to Panama flight.

Cheap Raleigh to Panama flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Raleigh to Panama

Best Price Found

$200

Fastest flight time

4h 32m

Direct flights

Mon, Tue, Thu, Fri and Sat

Airports in Panama

1 airport
The best one-way flight to Panama from Raleigh in the past 72 hours is $200. The best round-trip flight deal from Raleigh to Panama found on momondo in the last 72 hours is $356.
The fastest flight from Raleigh to Panama takes 4h 32m
Direct flights go from Raleigh to Panama on Monday, Tuesday, Thursday, Friday and Saturday. There are no airlines offering direct flights.
There is 1 airport near Panama: Panama City Tocumen Intl (PTY)
  • When did momondo last update prices for flights from Raleigh-Durham Airport to Panama?

    Prices for flights from Raleigh-Durham Airport to Panama are updated daily.

  • How many operators does momondo search for flights from Raleigh-Durham Airport to Panama?

  • How old do you have to be to fly from Raleigh-Durham Airport to Panama?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Raleigh-Durham Airport to Panama.

  • What documentation or ID do you need to fly to Panama?

    The required travel and health documents for your Panama trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Panama. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular plane model from Raleigh to Panama?

Best airlines flying from Raleigh to Panama

Compare and see reviews for airlines that fly from Raleigh to Panama with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $249Free CancellationRating
7.2
11,047 reviews
Search American Airlines flights
Copa AirlinesPriceFrom $318Free CancellationRating
7.6
1,565 reviews
Search Copa Airlines flights
DeltaPriceFrom $367Free CancellationRating
7.9
8,002 reviews
Search Delta flights
United AirlinesPriceFrom $409Free CancellationRating
7.4
9,030 reviews
Search United Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Raleigh to Panama?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Panama from Raleigh.

Can I find flights from Raleigh to Panama with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Raleigh to Panama flights to just show those with flexible booking policies.

How can momondo help me find flights from Raleigh to Panama?

momondo helps you find the best flight between Raleigh and Panama by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Raleigh to Panama right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Panama, momondo offers a useful price alert feature which will track prices for flights to Panama from Raleigh and alert you when they change.

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1 adult
Sun 12/21
Sun 12/28

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