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Cheap flights from Portland to Santiago de los Caballeros from $358

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Portland to Santiago de los Caballeros departing on 7/1. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Portland to Santiago de los Caballeros

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
1:52 pm - 12:23 pm
PDX
-
STI
19h 31m
2 stops
American Airlines Logo
1:32 pm - 10:20 am
STI
-
PDX
23h 48m
2 stops
$573American Airlines
Tue, May 12 - Fri, May 15
Delta Logo
11:03 pm - 12:23 pm
PDX
-
STI
10h 20m
1 stop
Delta Logo
8:59 pm - 11:46 am
STI
-
PDX
17h 47m
1 stop
$600Delta
Tue, May 12 - Fri, May 15
American Airlines Logo
1:52 pm - 12:23 pm
PDX
-
STI
19h 31m
2 stops
American Airlines Logo
1:32 pm - 10:20 am
STI
-
PDX
23h 48m
2 stops
$640American Airlines
Wed, May 6 - Sat, May 9
Delta Logo
7:00 am - 12:22 am
PDX
-
STI
14h 22m
1 stop
Delta Logo
8:59 pm - 11:46 am
STI
-
PDX
17h 47m
1 stop
$651Delta
Wed, May 6 - Fri, May 8
Delta Logo
5:30 am - 12:22 am
PDX
-
STI
15h 52m
2 stops
Delta Logo
8:59 pm - 11:46 am
STI
-
PDX
17h 47m
1 stop
$656Delta
Wed, May 6 - Fri, May 8
United Airlines Logo
5:30 am - 3:12 pm
PDX
-
STI
30h 42m
3 stops
United Airlines Logo
2:07 pm - 9:38 am
STI
-
PDX
22h 31m
2 stops
$721United Airlines
Tue, May 12 - Fri, May 15
American Airlines Logo
10:28 pm - 12:23 pm
PDX
-
STI
10h 55m
1 stop
American Airlines Logo
1:32 pm - 11:53 pm
STI
-
PDX
13h 21m
1 stop
$748American Airlines
Wed, May 6 - Sat, May 9
United Airlines Logo
7:05 pm - 12:57 pm
PDX
-
STI
14h 52m
2 stops
United Airlines Logo
6:00 am - 7:38 pm
STI
-
PDX
16h 38m
2 stops
$953United Airlines
Mon, May 11 - Fri, May 15
United Airlines Logo
10:52 pm - 12:57 pm
PDX
-
STI
11h 05m
1 stop
United Airlines Logo
2:07 pm - 9:39 am
STI
-
PDX
22h 32m
2 stops
$979United Airlines
Mon, Jun 1 - Mon, Jun 8
Delta Logo
10:05 pm - 12:03 pm
PDX
-
STI
10h 58m
1 stop
Delta Logo
8:05 pm - 11:50 am
STI
-
PDX
19h 45m
1 stop
$1,040Delta
Fri, Oct 16 - Fri, Feb 26

American Airlines flights from Portland to Santiago de los Caballeros

Our best American Airlines deals on Portland to Santiago de los Caballeros flight tickets
American Airlines
May 12
PDX1:52 pmPortland
19h 31m
2 stops
STI12:23 pmSantiago de los Caballeros
May 15
STI1:32 pmSantiago de los Caballeros
23h 48m
2 stops
PDX10:20 amPortland
$573
American Airlines
May 6
PDX1:52 pmPortland
19h 31m
2 stops
STI12:23 pmSantiago de los Caballeros
May 9
STI1:32 pmSantiago de los Caballeros
23h 48m
2 stops
PDX10:20 amPortland
$640
American Airlines
May 6
PDX10:28 pmPortland
10h 55m
1 stop
STI12:23 pmSantiago de los Caballeros
May 9
STI1:32 pmSantiago de los Caballeros
13h 21m
1 stop
PDX11:53 pmPortland
$748

Delta flights from Portland to Santiago de los Caballeros

Our best Delta deals on Portland to Santiago de los Caballeros flight tickets
Delta
May 12
PDX11:03 pmPortland
10h 20m
1 stop
STI12:23 pmSantiago de los Caballeros
May 15
STI8:59 pmSantiago de los Caballeros
17h 47m
1 stop
PDX11:46 amPortland
$600
Delta
May 6
PDX7:00 amPortland
14h 22m
1 stop
STI12:22 amSantiago de los Caballeros
May 8
STI8:59 pmSantiago de los Caballeros
17h 47m
1 stop
PDX11:46 amPortland
$651
Delta
May 6
PDX5:30 amPortland
15h 52m
2 stops
STI12:22 amSantiago de los Caballeros
May 8
STI8:59 pmSantiago de los Caballeros
18h 26m
2 stops
PDX12:25 pmPortland
$656

momondo Fare Finder

 
Customize your flight search to find flights from Portland to Santiago de los Caballeros that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated April 22, 2026.
Use the filters below to find and compare flights from Portland to Santiago de los Caballeros that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

PortlandSantiago de los Caballeros

PDX - STI

PDXSTI

Portland

Tue 5/12

1:52 pm-12:23 pm

2 stops19h 31m

Santiago de los Caballeros

Fri 5/15

1:32 pm-10:20 am

2 stops23h 48m

$573

PortlandSantiago de los Caballeros

PDX - STI

PDXSTI

Portland

Tue 5/12

11:03 pm-12:23 pm

1 stop10h 20m

Santiago de los Caballeros

Fri 5/15

8:59 pm-11:46 am

1 stop17h 47m

$600

PortlandSantiago de los Caballeros

PDX - STI

PDXSTI

Portland

Wed 5/6

1:52 pm-12:23 pm

2 stops19h 31m

Santiago de los Caballeros

Sat 5/9

1:32 pm-10:20 am

2 stops23h 48m

$640

PortlandSantiago de los Caballeros

PDX - STI

PDXSTI

Portland

Wed 5/6

7:00 am-12:22 am

1 stop14h 22m

Santiago de los Caballeros

Fri 5/8

8:59 pm-11:46 am

1 stop17h 47m

$651

PortlandSantiago de los Caballeros

PDX - STI

PDXSTI

Portland

Wed 5/6

5:30 am-12:22 am

2 stops15h 52m

Santiago de los Caballeros

Fri 5/8

8:59 pm-11:46 am

1 stop17h 47m

$656

PortlandSantiago de los Caballeros

PDX - STI

PDXSTI

Portland

Tue 5/12

5:30 am-3:12 pm

3 stops30h 42m

Santiago de los Caballeros

Fri 5/15

2:07 pm-9:38 am

2 stops22h 31m

$721
Quickest round-trip

PortlandSantiago de los Caballeros

PDX - STI

PDXSTI

Portland

Wed 5/6

10:28 pm-12:23 pm

1 stop10h 55m

Santiago de los Caballeros

Sat 5/9

1:32 pm-11:53 pm

1 stop13h 21m

$748

PortlandSantiago de los Caballeros

PDX - STI

PDXSTI

Portland

Mon 5/11

7:05 pm-12:57 pm

2 stops14h 52m

Santiago de los Caballeros

Fri 5/15

6:00 am-7:38 pm

2 stops16h 38m

$953

PortlandSantiago de los Caballeros

PDX - STI

PDXSTI

Portland

Mon 6/1

10:52 pm-12:57 pm

1 stop11h 05m

Santiago de los Caballeros

Mon 6/8

2:07 pm-9:39 am

2 stops22h 32m

$979

PortlandSantiago de los Caballeros

PDX - STI

PDXSTI

Portland

Fri 10/16

10:05 pm-12:03 pm

1 stop10h 58m

Santiago de los Caballeros

Fri 2/26

8:05 pm-11:50 am

1 stop19h 45m

$1,040

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 18 resultsSorted by cheapest first
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See travel insights to Santiago de los Caballeros from

How to get the cheapest flight ticket from Portland to Santiago de los Caballeros

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Can stopping save me money on Portland to Santiago de los Caballeros flights?

You could potentially save up to 42% on your flight if you consider stops on a Portland to Santiago de los Caballeros flight.

When to book flights from Portland to Santiago de los Caballeros

Are you open to changing your travel dates? Check out the ideal times to fly from Portland to Santiago de los Caballeros according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Portland to Santiago de los Caballeros (PDX to STI) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Portland to Santiago de los Caballeros

Fastest flight time

11h 05m

Direct flights

None
The fastest flight from Portland to Santiago de los Caballeros takes 11h 05m
There are no direct flights from Portland to Santiago de los Caballeros. There are no popular flight routes from Portland to Santiago de los Caballeros.
Search flight deals

Frequently asked questions about flying from Portland to Santiago de los Caballeros

  • How far is Portland to Santiago de los Caballeros by plane?

    Portland and Santiago de los Caballeros are 3443.3 mi apart from one another. Flights usually cover this in 11h 05m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Portland Airport to Santiago de los Caballeros Airport?

    Prices for flights from Portland Airport to Santiago de los Caballeros Airport are updated daily.

  • How many operators does momondo search for flights from Portland Airport to Santiago de los Caballeros Airport?

  • How old do you have to be to fly from Portland Airport to Santiago de los Caballeros Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Portland Airport to Santiago de los Caballeros Airport.

  • What documentation or ID do you need to fly to Santiago de los Caballeros Airport?

    The travel and health documents required for your trip to Santiago de los Caballeros Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Santiago de los Caballeros Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular airline from Portland to Santiago de los Caballeros?

Best airlines flying from Portland to Santiago de los Caballeros

Compare and see reviews for airlines that fly from Portland to Santiago de los Caballeros with momondo
Airline
Rating
Free Cancellation
Price
United AirlinesPriceFrom $467Free CancellationRating
7.4
9,625 reviews
Search United Airlines flights
American AirlinesPriceFrom $492Free CancellationRating
7.1
11,647 reviews
Search American Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Portland to Santiago de los Caballeros?

Finding the right flight to Santiago de los Caballeros from Portland is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Santiago de los Caballeros quick and easy, saving you time and money.

Can I find flights from Portland to Santiago de los Caballeros with flexible booking policies on momondo?

All flight searches from Portland to Santiago de los Caballeros on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Portland to Santiago de los Caballeros?

momondo provides multiple filters to help you find the best flight to Santiago de los Caballeros from Portland. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Portland to Santiago de los Caballeros right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Santiago de los Caballeros from Portland. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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