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Cheap flights from Portland to Santiago de los Caballeros from $241

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Portland to Santiago de los Caballeros departing on 9/25. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Portland to Santiago de los Caballeros (PDX-STI)

Cheap round-trip flights

Delta Logo
7:05 am - 12:59 amPDX-STI
13h 54m1 stop
Delta Logo
6:45 am - 9:39 pmSTI-PDX
18h 54m1 stop
$525Delta
Find Deal
Tue, Nov 25 - Tue, Dec 9
United Airlines Logo
10:32 pm - 12:57 pmPDX-STI
11h 25m1 stop
United Airlines Logo
6:00 am - 10:30 pmSTI-PDX
19h 30m2 stops
$527United Airlines
Find Deal
Sat, Oct 11 - Sat, Oct 18
United Airlines Logo
8:35 am - 1:46 amPDX-STI
14h 11m2 stops
United Airlines Logo
6:00 am - 6:40 pmSTI-PDX
16h 40m2 stops
$529United Airlines
Find Deal
Sat, Oct 25 - Sat, Nov 8
Delta Logo
7:05 am - 12:59 amPDX-STI
13h 54m1 stop
Delta Logo
6:45 am - 10:20 pmSTI-PDX
19h 35m2 stops
$530Delta
Find Deal
Tue, Nov 25 - Tue, Dec 9
Delta Logo
7:12 am - 12:24 amPDX-STI
14h 12m1 stop
Delta Logo
8:31 pm - 12:06 pmSTI-PDX
18h 35m1 stop
$533Delta
Find Deal
Sat, Oct 11 - Sat, Oct 18
Delta Logo
7:12 am - 12:24 amPDX-STI
14h 12m1 stop
Delta Logo
7:00 am - 9:10 pmSTI-PDX
18h 10m1 stop
$534Delta
Find Deal
Sat, Oct 25 - Sat, Nov 8
American Airlines Logo
10:45 pm - 3:32 pmPDX-STI
12h 47m1 stop
American Airlines Logo
4:32 pm - 11:52 pmSTI-PDX
11h 20m1 stop
$575American Airlines
Find Deal
Mon, Nov 24 - Mon, Dec 8
American Airlines Logo
2:16 pm - 12:55 pmPDX-STI
18h 39m2 stops
American Airlines Logo
7:00 am - 7:32 pmSTI-PDX
16h 32m2 stops
$626American Airlines
Find Deal
Sat, Jan 10 - Sat, Jan 17
American Airlines Logo
6:00 am - 10:56 pmPDX-STI
12h 56m2 stops
American Airlines Logo
6:04 am - 11:23 pmSTI-PDX
21h 19m2 stops
$630American Airlines
Find Deal
Sat, Nov 22 - Sat, Dec 6
American Airlines Logo
12:59 am - 10:56 pmPDX-STI
17h 57m2 stops
American Airlines Logo
6:04 am - 11:23 pmSTI-PDX
21h 19m2 stops
$726American Airlines
Find Deal
Fri, Nov 21 - Sat, Dec 6

Delta flights from Portland to Santiago de los Caballeros

Our best Delta deals on Portland to Santiago de los Caballeros flight tickets
Delta
Nov 25
PDX7:05 amPortland
13h 54m
1 stop
STI12:59 amSantiago de los Caballeros
Dec 9
STI6:45 amSantiago de los Caballeros
18h 54m
1 stop
PDX9:39 pmPortland
$525
Find similar
Delta
Nov 25
PDX7:05 amPortland
13h 54m
1 stop
STI12:59 amSantiago de los Caballeros
Dec 9
STI6:45 amSantiago de los Caballeros
19h 35m
2 stops
PDX10:20 pmPortland
$530
Find similar
Delta
Oct 11
PDX7:12 amPortland
14h 12m
1 stop
STI12:24 amSantiago de los Caballeros
Oct 18
STI8:31 pmSantiago de los Caballeros
18h 35m
1 stop
PDX12:06 pmPortland
$533
Find similar

American Airlines flights from Portland to Santiago de los Caballeros

Our best American Airlines deals on Portland to Santiago de los Caballeros flight tickets
American Airlines
Nov 24
PDX10:45 pmPortland
12h 47m
1 stop
STI3:32 pmSantiago de los Caballeros
Dec 8
STI4:32 pmSantiago de los Caballeros
11h 20m
1 stop
PDX11:52 pmPortland
$575
Find similar
American Airlines
Jan 10
PDX2:16 pmPortland
18h 39m
2 stops
STI12:55 pmSantiago de los Caballeros
Jan 17
STI7:00 amSantiago de los Caballeros
16h 32m
2 stops
PDX7:32 pmPortland
$626
Find similar
American Airlines
Nov 22
PDX6:00 amPortland
12h 56m
2 stops
STI10:56 pmSantiago de los Caballeros
Dec 6
STI6:04 amSantiago de los Caballeros
21h 19m
2 stops
PDX11:23 pmPortland
$630
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Portland to Santiago de los Caballeros that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 27, 2025.
Use the filters below to find and compare flights from Portland to Santiago de los Caballeros that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

PortlandSantiago de los Caballeros

PDX - STI

PDXSTI

Portland

Tue 11/25

7:05 am-12:59 am

1 stop13h 54m

Santiago de los Caballeros

Tue 12/9

6:45 am-9:39 pm

1 stop18h 54m

$525

PortlandSantiago de los Caballeros

PDX - STI

PDXSTI

Portland

Sat 10/11

10:32 pm-12:57 pm

1 stop11h 25m

Santiago de los Caballeros

Sat 10/18

6:00 am-10:30 pm

2 stops19h 30m

$527

PortlandSantiago de los Caballeros

PDX - STI

PDXSTI

Portland

Sat 10/25

8:35 am-1:46 am

2 stops14h 11m

Santiago de los Caballeros

Sat 11/8

6:00 am-6:40 pm

2 stops16h 40m

$529

PortlandSantiago de los Caballeros

PDX - STI

PDXSTI

Portland

Tue 11/25

7:05 am-12:59 am

1 stop13h 54m

Santiago de los Caballeros

Tue 12/9

6:45 am-10:20 pm

2 stops19h 35m

$530

PortlandSantiago de los Caballeros

PDX - STI

PDXSTI

Portland

Sat 10/11

7:12 am-12:24 am

1 stop14h 12m

Santiago de los Caballeros

Sat 10/18

8:31 pm-12:06 pm

1 stop18h 35m

$533

PortlandSantiago de los Caballeros

PDX - STI

PDXSTI

Portland

Sat 10/25

7:12 am-12:24 am

1 stop14h 12m

Santiago de los Caballeros

Sat 11/8

7:00 am-9:10 pm

1 stop18h 10m

$534

PortlandSantiago de los Caballeros

PDX - STI

PDXSTI

Portland

Mon 11/24

10:45 pm-3:32 pm

1 stop12h 47m

Santiago de los Caballeros

Mon 12/8

4:32 pm-11:52 pm

1 stop11h 20m

$575

PortlandSantiago de los Caballeros

PDX - STI

PDXSTI

Portland

Sat 1/10

2:16 pm-12:55 pm

2 stops18h 39m

Santiago de los Caballeros

Sat 1/17

7:00 am-7:32 pm

2 stops16h 32m

$626

PortlandSantiago de los Caballeros

PDX - STI

PDXSTI

Portland

Sat 11/22

6:00 am-10:56 pm

2 stops12h 56m

Santiago de los Caballeros

Sat 12/6

6:04 am-11:23 pm

2 stops21h 19m

$630

PortlandSantiago de los Caballeros

PDX - STI

PDXSTI

Portland

Fri 11/21

12:59 am-10:56 pm

2 stops17h 57m

Santiago de los Caballeros

Sat 12/6

6:04 am-11:23 pm

2 stops21h 19m

$726

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Santiago de los Caballeros from

How to get the cheapest flight ticket from Portland to Santiago de los Caballeros

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to Santiago de los Caballeros?

The cheapest day to depart from Portland to Santiago de los Caballeros is on a Saturday when prices can be found for as low as $609. When flying out on a Monday, the most expensive travel day of the week, you can expect to see flight prices from Portland to Santiago de los Caballeros for around $1,131.

What is the cheapest time of day to depart on your flight to Santiago de los Caballeros?

Our data shows that the cheapest Portland to Santiago de los Caballeros flights are usually those with departure times in the afternoon. Our users have found flights to Santiago de los Caballeros in the afternoon for as low as $558. In the morning is when there is more demand to fly to Santiago de los Caballeros, so prices are often more expensive at around $821 per ticket.

Can stopping save me money on Portland to Santiago de los Caballeros flights?

You could potentially save up to 38% on your flight if you consider stops on a Portland to Santiago de los Caballeros flight.

When to book flights from Portland to Santiago de los Caballeros

Are you open to changing your travel dates? Check out the ideal times to fly from Portland to Santiago de los Caballeros according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Portland to Santiago de los Caballeros (PDX to STI) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Portland to Santiago de los Caballeros

Direct flights

None
There are no direct flights from Portland to Santiago de los Caballeros. There are no popular flight routes from Portland to Santiago de los Caballeros.
Search flight deals

  • How far is Portland to Santiago de los Caballeros by plane?

    Portland and Santiago de los Caballeros are 3443.3 mi apart from one another. Flights usually cover this in 9h 59m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Portland Airport to Santiago de los Caballeros Airport?

    Prices for flights from Portland Airport to Santiago de los Caballeros Airport are updated daily.

  • How many operators does momondo search for flights from Portland Airport to Santiago de los Caballeros Airport?

  • How old do you have to be to fly from Portland Airport to Santiago de los Caballeros Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Portland Airport to Santiago de los Caballeros Airport.

  • What documentation or ID do you need to fly to Santiago de los Caballeros Airport?

    The travel and health documents required for your trip to Santiago de los Caballeros Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Santiago de los Caballeros Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular airline from Portland to Santiago de los Caballeros?

Best airlines flying from Portland to Santiago de los Caballeros

Compare and see reviews for airlines that fly from Portland to Santiago de los Caballeros with momondo
Airline
Rating
Free Cancellation
Price
United AirlinesPriceFrom $514Free CancellationRating
7.4
8,945 reviews
Search United Airlines flights
DeltaPriceFrom $536Free CancellationRating
7.9
7,977 reviews
Search Delta flights
American AirlinesPriceFrom $569Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Portland to Santiago de los Caballeros?

Finding the right flight to Santiago de los Caballeros from Portland is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Santiago de los Caballeros quick and easy, saving you time and money.

Can I find flights from Portland to Santiago de los Caballeros with flexible booking policies on momondo?

All flight searches from Portland to Santiago de los Caballeros on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Portland to Santiago de los Caballeros?

momondo provides multiple filters to help you find the best flight to Santiago de los Caballeros from Portland. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Portland to Santiago de los Caballeros right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Santiago de los Caballeros from Portland. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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